CN109187609A - A kind of anti-microbial effectiveness evaluation method of antibiotic glass - Google Patents
A kind of anti-microbial effectiveness evaluation method of antibiotic glass Download PDFInfo
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- CN109187609A CN109187609A CN201811032673.XA CN201811032673A CN109187609A CN 109187609 A CN109187609 A CN 109187609A CN 201811032673 A CN201811032673 A CN 201811032673A CN 109187609 A CN109187609 A CN 109187609A
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- Prior art keywords
- antibiotic glass
- antibacterial
- glass
- antibiotic
- antibacterial oxide
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N23/00—Investigating or analysing materials by the use of wave or particle radiation, e.g. X-rays or neutrons, not covered by groups G01N3/00 – G01N17/00, G01N21/00 or G01N22/00
- G01N23/22—Investigating or analysing materials by the use of wave or particle radiation, e.g. X-rays or neutrons, not covered by groups G01N3/00 – G01N17/00, G01N21/00 or G01N22/00 by measuring secondary emission from the material
- G01N23/223—Investigating or analysing materials by the use of wave or particle radiation, e.g. X-rays or neutrons, not covered by groups G01N3/00 – G01N17/00, G01N21/00 or G01N22/00 by measuring secondary emission from the material by irradiating the sample with X-rays or gamma-rays and by measuring X-ray fluorescence
Abstract
The invention discloses a kind of anti-microbial effectiveness evaluation method of antibiotic glass, this method be by establishing antibacterial oxide XRF standard curve, the uniformity datas of the antibacterial oxide components content in measurement antibiotic glass and computational representation antibiotic glass antibacterial characteristics determine the anti-microbial effectiveness of antibiotic glass.Method of the invention is calculated by using the content detection and its uniformity that hand-held XRF carries out antibacterial oxide at multiple positions to antibiotic glass, can accurate and effectively evaluating antibiotic glass anti-microbial property, provide effective means for antibiotic glass product of production line quality testing.
Description
Technical field
The invention belongs to antibiotic glass fields, and in particular to a kind of anti-microbial effectiveness evaluation method of antibiotic glass.
Background technique
Enhancing with people to quality of life and environmental consciousness, antibiotic glass have gradually been big well known and hot
It holds in both hands.Antibiotic glass refers to built-in anti-microbial property, and bacterium (Escherichia coli, staphylococcus aureus) can be inhibited to grow,
And a kind of functional glass that service life is lasting.Antibiotic glass on the market is broadly divided into plated film antibiotic glass and tempering at present
Two kinds of antibiotic glass, wherein tempering antibiotic glass is salt (such as AgNO that will have antibacterial characteristics3、CuSO4、ZnSO4Deng) be placed in
In tempering fused salt, at a certain temperature, by regular hour, Ag+、Cu2+Deng by with ion (such as Na certain in glass+、
K+) ion exchange is carried out to be implanted to glass surface, and then realize the anti-microbial property of glass, and it compares plated film antibiotic glass
With more Durability of antimicrobial effect.
The ability that antibiotic glass inhibits or kill pathogenic microorganism is referred to as antibacterium rate or antibacterial activity, test method
For observation viable count after glass product progress microbionation culture is calculated antibacterial activity value (R value).It is evaluated by R value anti-
The anti-microbial property of bacterium glass, R value is bigger, and the antibacterial higher grade that represents, and R value is generally required to be greater than 2(i.e. antibiotic rate > 99%) more than,
It is JIS Z2801:2000 etc. with reference to testing standard.R value test period is long (usually one week or more), and to the special of tester
Industry technical level requires height, so kind anti-microbial property evaluation method is difficult to meet the requirement that production product quality quickly detects, shadow
Ring product turnout etc..Therefore, in order to solve this problem, it is necessary to which a kind of antibiotic glass anti-microbial effectiveness of efficiently and accurately is provided
Evaluation method.
Summary of the invention
The purpose of the present invention is to provide a kind of anti-microbial effectiveness evaluation method of antibiotic glass, this method is based on antibacterial
The principle of glass is set out, and has the oxide content of anti-microbial property by detection glass surface, accurate and efficient.
To achieve the above object, the present invention adopts the following technical scheme:
A kind of anti-microbial effectiveness evaluation method of antibiotic glass, the described method comprises the following steps:
1) it establishes XRF standard curve: using the serial antibiotic glass sample containing known antibacterial oxide concentration, establish its antibacterial
The corresponding XRF standard curve of oxide；
2) the antibacterial oxide components in antibiotic glass are measured: antibiotic glass to be measured is subjected to the division of n lattice, are detected each in every lattice
The fluorescence X transmitted intensity of antibacterial oxide, and calculated in every lattice antibiotic glass according to XRF standard curve obtained by step (1)
The content of each antibacterial oxide；
3) it characterizes the uniformity of antibiotic glass antibacterial characteristics: the n group antibacterial oxide content of test calculate by formula
With the average value of the n group antibacterial oxide content of a piece of antibiotic glassWith uniformity H, then according to its numerical value determine antibiotic glass
Anti-microbial property, specific formula is as follows:
In above formula:For the average value of the antibacterial oxide content at the multiple positions of same sheet glass, n is test position points,
Xi is the antibacterial oxide content detected value at i-th of position, and S is mean square deviation, and H is the uniformity；
Antibacterial oxide includes Ag in the step (1)2O, one or more of in CuO and ZnO.
The fluorescence X transmitted intensity instrument of each antibacterial oxide is hand-held X-ray in the every lattice of detection in the step (2)
Fluorescence Spectrometer.
In the anti-microbial property evaluation of step (3) antibiotic glass, whenWhen >=0.01%, H >=95%, the antibacterial glass
Glass has anti-microbial property.
Beneficial effects of the present invention: the antibiotic glass detecting instrument that the present invention uses is preferably hand-held x-ray fluorescence light
Spectrometer (XRF), compares the composition detections instrument such as table type X ray Fluorescence Spectrometer, XPS, and hand-held XRF has not by sample size
Limitation, the advantages such as easy to detect, detection speed is fast, and antibiotic glass resist at multiple positions by using hand-held XRF
The content detection and its uniformity of bacterium oxide calculate, can accurate and effectively evaluating antibiotic glass anti-microbial property, be anti-
The detection of bacterium glass production line product quality provides effective means.
Detailed description of the invention
Fig. 1 is Ag2The XRF standard curve of O.
Specific embodiment
In order to make content of the present invention easily facilitate understanding, With reference to embodiment to of the present invention
Technical solution is described further, but the present invention is not limited only to this.
Embodiment 1
(1) XRF standard curve is established: using containing Ag2The serial antibiotic glass sample of O concentration, establishes Ag in antibiotic glass2O pairs
The XRF standard curve (such as Fig. 1) answered；
(2) Ag in antibiotic glass is measured2O ingredient: antibiotic glass to be measured is subjected to 9 lattice divisions, detects each Ag in every lattice2O's is glimmering
Light X transmitted intensity, and according to each Ag2The corresponding XRF standard curve of O calculates each Ag in every lattice antibiotic glass2The content of O；
(3) uniformity of antibiotic glass antibacterial characteristics is characterized: by 9 groups of Ag of test2O content is carried out calculating with a piece of by formula
9 groups of Ag of antibiotic glass2The average value of O contentWith uniformity H, then according to its numerical value determine antibiotic glass anti-microbial property,
Specific formula is as follows:
In above formula:For the average value of the antibacterial oxide content at the n position with a piece of antibiotic glass, n is test position
Points, xi are the antibacterial oxide content detected value at i-th of position, and S is mean square deviation, and H is the uniformity；
It tests 10 groups of antibiotic glass samples respectively by above method, while 10 groups of antibiotic glass samples is subjected to microbionation training
Viable count is observed after supporting to calculate antibacterial activity value (R value), evaluates the anti-microbial property of antibiotic glass, test result is as follows:
By chart it is found that anti-microbial effectiveness evaluation method of the invention is consistent with antibacterial activity R value evaluation method result, when
When >=0.01%, H >=95%, the antibiotic glass has anti-microbial property, and works asWhen >=0.02%, H >=97%, the antibacterial glass
Glass has excellent anti-microbial property.
The foregoing is merely presently preferred embodiments of the present invention, all equivalent changes done according to scope of the present invention patent with
Modification, is all covered by the present invention.
Claims (4)
1. a kind of anti-microbial effectiveness evaluation method of antibiotic glass, it is characterised in that: the described method comprises the following steps:
(1) it establishes XRF standard curve: antibiotic glass is established using the serial antibiotic glass sample containing known antibacterial oxide concentration
The corresponding XRF standard curve of middle antibacterial oxide；
(2) it measures antibacterial oxide components content in antibiotic glass: antibiotic glass to be measured being subjected to the division of n lattice, is detected in every lattice
The fluorescence X transmitted intensity of each antibacterial oxide, and every lattice antibiotic glass is calculated according to XRF standard curve obtained by step (1)
In each antibacterial oxide content；
(3) the anti-microbial property evaluation of antibiotic glass: the n group antibacterial oxide content of test is calculated by formula, is obtained same
The average value of the n group antibacterial oxide content of piece antibiotic glassWith uniformity H, then resisting according to its numerical value judgement antibiotic glass
Bacterium performance, specific formula is as follows:
In above formula:For the average value of the antibacterial oxide content at the n position with a piece of antibiotic glass, n is test position
Points, xi are the antibacterial oxide content detected value at i-th of position, and S is mean square deviation, and H is the uniformity.
2. a kind of anti-microbial effectiveness evaluation method of antibiotic glass according to claim 1, it is characterised in that: the step
Suddenly antibacterial oxide includes Ag in (1)2O, one or more of in CuO and ZnO.
3. a kind of anti-microbial effectiveness evaluation method of antibiotic glass according to claim 1, it is characterised in that: the step
Suddenly the fluorescence X transmitted intensity instrument of each antibacterial oxide is hand-held Xray fluorescence spectrometer in the every lattice of detection in (2).
4. a kind of anti-microbial effectiveness evaluation method of antibiotic glass according to claim 1, it is characterised in that: the step
Suddenly in the anti-microbial property evaluation of (3) antibiotic glass, whenWhen >=0.01%, H >=95%, the antibiotic glass has anti-microbial property.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201811032673.XA CN109187609A (en) | 2018-09-05 | 2018-09-05 | A kind of anti-microbial effectiveness evaluation method of antibiotic glass |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201811032673.XA CN109187609A (en) | 2018-09-05 | 2018-09-05 | A kind of anti-microbial effectiveness evaluation method of antibiotic glass |
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| CN109187609A true CN109187609A (en) | 2019-01-11 |
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| CN201811032673.XA Pending CN109187609A (en) | 2018-09-05 | 2018-09-05 | A kind of anti-microbial effectiveness evaluation method of antibiotic glass |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112198130A (en) * | 2020-10-22 | 2021-01-08 | 北方华锦化学工业股份有限公司 | Method for rapidly detecting antibacterial performance of antibacterial ABS product in production |
| CN112209634A (en) * | 2020-09-11 | 2021-01-12 | 科立视材料科技有限公司 | Antibacterial molten salt, glass and preparation method |
Citations (4)
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|---|---|---|---|---|
| CN102928451A (en) * | 2012-11-01 | 2013-02-13 | 白雪冰 | Method for testing uniformity of glass fusion piece |
| CN103323479A (en) * | 2013-06-18 | 2013-09-25 | 芜湖东旭光电科技有限公司 | Glass mixed batch uniformity determination method |
| CN107614448A (en) * | 2015-05-29 | 2018-01-19 | 旭硝子株式会社 | Ultraviolet (uv) transmission glass |
| CN107843610A (en) * | 2017-10-31 | 2018-03-27 | 巨石集团九江有限公司 | A kind of method of testing of cell furnace batch uniformity |
-
2018
- 2018-09-05 CN CN201811032673.XA patent/CN109187609A/en active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102928451A (en) * | 2012-11-01 | 2013-02-13 | 白雪冰 | Method for testing uniformity of glass fusion piece |
| CN103323479A (en) * | 2013-06-18 | 2013-09-25 | 芜湖东旭光电科技有限公司 | Glass mixed batch uniformity determination method |
| CN107614448A (en) * | 2015-05-29 | 2018-01-19 | 旭硝子株式会社 | Ultraviolet (uv) transmission glass |
| CN107843610A (en) * | 2017-10-31 | 2018-03-27 | 巨石集团九江有限公司 | A kind of method of testing of cell furnace batch uniformity |
Non-Patent Citations (1)
| Title |
|---|
| 梁金生 等: ""无机非金属材料的抗菌性能"", 《豆丁网 HTTPS://WWW.DOCIN.COM/P-787336427.HTML》 * |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112209634A (en) * | 2020-09-11 | 2021-01-12 | 科立视材料科技有限公司 | Antibacterial molten salt, glass and preparation method |
| CN112198130A (en) * | 2020-10-22 | 2021-01-08 | 北方华锦化学工业股份有限公司 | Method for rapidly detecting antibacterial performance of antibacterial ABS product in production |
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Application publication date: 20190111 |
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