Disclosure of Invention
In view of the above technical problems in the prior art, embodiments of the present invention provide an aerosol physical therapy device with continuous drug delivery.
In order to solve the technical problem, the embodiment of the invention adopts the following technical scheme:
an aerosol physical therapy device having a continuous drug delivery function, comprising:
a medicine source container in which a liquid medicine is contained;
a power pump connected with the medicine source container through a first conduit for sucking the medicine in the medicine source container;
the atomization mechanism is connected with the power pump through a second conduit to receive the medicine supplied by the power pump and atomize the medicine;
a reservoir mechanism including a housing having a variable chamber formed therein, the variable chamber communicating with the second conduit through a branch, such that when the powered pump is operating, drug passing through the second conduit enters the variable chamber via the branch for storage, such that when the powered pump is stopped, the variable chamber forces drug into the aerosolizing mechanism via the branch, the second conduit, by reducing volume.
Preferably, the second conduit between the branch and the power pump is further provided with a switch valve, and when the power pump is operated, the switch valve is opened, and when the power pump is stopped, the switch valve is closed.
Preferably, the liquid storage mechanism further comprises an elastic dividing film and a first spring; the elastic dividing membrane is used for dividing the interior of the shell into an upper chamber and a lower chamber, and the lower chamber forms the variable chamber; the middle part of membrane is cut apart to elasticity is formed with the push block, first spring set up in the upper chamber, its both ends are used for the butt respectively the casing with the push block, wherein:
the upper part of the shell is provided with a through hole, and the through hole is used for communicating the upper cavity with the outside air.
Preferably, a partition plate is further arranged in the lower chamber and used for dividing the lower chamber into a first sub-chamber and a second sub-chamber; wherein:
the dividing plate is provided with a first one-way valve and a second one-way valve; an inlet and an outlet of the first one-way valve are respectively communicated with the first sub-chamber and the second sub-chamber correspondingly; and the inlet and the outlet of the second one-way valve are respectively communicated with the second sub-chamber and the first sub-chamber correspondingly.
Preferably, a flow limiting body is arranged on the second conduit between the branch and the atomization mechanism; the flow limiting body is provided with a flow guide hole, and the flow guide hole is used for limiting the flow of the medicine which enters the atomizing mechanism through the second conduit.
Preferably, a constant current mechanism is further arranged on the branch; the constant flow mechanism controls the flow of the medicine flowing into the atomization mechanism from the liquid storage mechanism according to the pressure of the medicine in a second conduit between the flow limiting body and the atomization mechanism, so that the flow of the medicine flowing into the atomization mechanism is kept constant.
Preferably, the constant current mechanism includes:
the holding body is internally provided with a sliding cavity;
the sliding core is arranged in the sliding cavity and can slide along the sliding cavity, and the sliding core divides the sliding cavity into a first closed cavity and a second closed cavity;
a liquid inlet bend which penetrates from the outside of the holding body to the sliding cavity, and is communicated with the variable cavity through a branch;
a liquid outlet bend which penetrates from the outside of the holding body to the sliding cavity so that the medicine in the variable cavity can enter the liquid outlet bend through the sliding cavity, and the liquid outlet bend is communicated with the second conduit through the branch;
the second spring is arranged in the second closed cavity and used for pushing the sliding core;
the first control channel is used for communicating the first closed cavity with the liquid outlet bend;
a second control passage extending from the exterior of the retention body through to the second enclosed cavity;
a control line for communicating a second conduit between the atomizing mechanism and the flow restrictor to the second control passage.
Preferably, an area of the inner wall of the flow guide hole is covered with an elastic bag, a plug penetrates through the flow limiting body, and the plug pushes against the elastic bag to enable the elastic bag to protrude out of the inner wall of the flow guide hole so as to reduce the through-flow section of the medicine flowing through the flow guide hole; wherein:
the outer part of the flow limiting body is also provided with a rotating nut which is coaxially opposite to the plug;
the opposite ends of the rotating nut and the plug are respectively provided with a magnet;
the two magnets are respectively formed into a ring shape by butting two arc-shaped magnetic sections, and the opposite magnetic poles of the two arc-shaped magnetic sections of each magnet face the same direction, so that the magnetic repulsion force between the two magnets is changed by rotating the rotating nut.
Compared with the prior art, the atomization physical therapy instrument with the continuous drug delivery function disclosed by the invention has the beneficial effects that: after the medicine in the medicine source container is used up, the liquid storage mechanism replaces the medicine source container and the power pump and provides liquid medicine for the atomizing mechanism, so that the medicine can be continuously provided for the atomizing mechanism, and time is gained for the whole replacement of the medicine source container or the refilling of the medicine.
Detailed Description
In order to make the technical solutions of the present invention better understood, the present invention will be described in detail below with reference to the accompanying drawings and specific embodiments.
As shown in fig. 1, an embodiment of the present invention discloses an aerosol physical therapy device with a continuous drug delivery function, which can be used to provide an aerosol drug to a patient with a respiratory disease, so that the drug can directly act on a focus, thereby alleviating or curing the disease. The atomization physical therapy instrument with the continuous drug delivery function comprises: a drug source container, a power pump 20, an atomizing mechanism 30 and a liquid storage mechanism 40. The medicine source container 10 may be made of plastic, glass, etc. and is used for containing liquid medicine; the power mechanism is connected to the medicine source container 10 through the first conduit 51, the first conduit 51 extends to a position below the liquid level of the medicine in the medicine source container 10, and the power pump 20 operates to suck the medicine in the medicine source container 10 through the first conduit 51. The atomizing mechanism 30 is capable of atomizing the medicine supplied therein, the atomizing mechanism 30 is further provided with a cover for being fastened to the face of the patient to supply the atomized medicine to the patient, so as to facilitate the patient to inhale the atomized medicine, the atomizing mechanism 30 is connected to the power pump 20 through the second conduit 52, and the power pump 20 supplies the sucked liquid medicine to the atomizing mechanism 30 through the second conduit 52 to atomize the medicine. The liquid storage mechanism 40 includes a housing 41, and a variable chamber is defined in the housing 41, and is characterized in that: the volume of the variable chamber can be increased by the medicine entering the variable chamber, and meanwhile, the medicine entering the variable chamber is extruded to have certain pressure; the variable chamber communicates with the second conduit 52 through a branch 53. Thus, during the initial phase of operation of the power pump 20, a portion of the drug drawn by the power pump 20 enters the aerosolization mechanism 30 via the second conduit 52 for aerosolization, and another portion of the drug enters the variable chamber of the housing 41 via the branch 53, such that the portion of the drug is stored in the variable chamber, and at the same time the variable chamber is continuously forced to increase in volume to accommodate more drug; when the volume of the variable chamber increases to a limit, all of the drug drawn by the powered pump 20 enters the aerosolization mechanism 30 through the second conduit 52. After the medicine in the medicine source container 10 is used up, the power pump 20 cannot supply the medicine to the atomizing mechanism 30, and at this time, the medicine in the variable chamber enters the atomizing mechanism 30 through the branch 53 and the second conduit 52 under a certain pressure.
The advantages of the above embodiment are: after the drug in the drug source container 10 is used up, the liquid storage mechanism 40 supplies the liquid drug to the atomizing mechanism 30 instead of the drug source container 10 and the power pump 20, so that the drug can be continuously supplied to the atomizing mechanism 30 to gain time for the entire replacement of the drug source container 10 or the refilling of the drug.
To prevent the liquid storage mechanism 40 from flowing back into the power pump 20 (or even back through the power pump 20 to the first conduit 51) when providing the nebulizing mechanism 30 with the drug, in a preferred embodiment of the present invention, as shown in fig. 1, the second conduit 52 between the branch 53 and the power pump 20 is further provided with an on-off valve 70, which is opened when the power pump 20 is running and closed when the power pump 20 is stopped. In this way, when the powered pump 20 is sucking the medicine from the medicine source container 10, the sucked medicine can smoothly enter the atomizing mechanism 30 through the second conduit 52, and when the medicine in the medicine source container 10 is used up and the powered pump 20 stops operating, the on-off valve 70 is closed so that the medicine flowing out of the liquid storage mechanism 40 does not flow back to the powered pump 20 or the first conduit 51. Preferably, the switching valve 70 is a solenoid valve controlled by an electric signal.
While there are various ways of forming the variable volume chamber that enables the above-described features to be formed in the housing 41, in a preferred embodiment of the present invention, as shown in fig. 3, the liquid storage mechanism 40 further includes an elastic dividing membrane 42, a first spring 44; the elastic dividing film 42 is used to divide the interior of the housing 41 into an upper chamber 461 and a lower chamber 462, the lower chamber 462 being formed as the above-described variable chamber; the middle of the elastic dividing film 42 is formed with a pushing block 43, the first spring 44 is disposed in the upper chamber 461, and two ends thereof are respectively used for abutting against the housing 41 and the pushing block 43, wherein: a through hole 411 is formed at an upper portion of the housing 41, and the through hole 411 is used to communicate the upper chamber 461 with the outside air.
The working process of the liquid storage mechanism 40 provided by the above embodiment is as follows:
in the initial stage of the operation of the power pump 20, as shown in fig. 4, a portion of the medicine sucked by the power pump 20 directly enters the atomizing mechanism 30 through the second conduit 52 for atomization, another portion enters the lower chamber 462 of the housing 41 through the branch 53, the medicine entering the lower chamber 462 forces the elastic dividing membrane 42 to stretch and deform in the direction of the upper chamber 461 due to the increasing volume, meanwhile, the pushing block 43 synchronously moves toward the upper chamber 461, the first spring 44 compresses correspondingly, the reaction force of the first spring 44 on the pushing block 43 causes the medicine in the lower chamber 462 to have a certain pressure, the container in the upper chamber 461 decreases with the increase of the container in the lower chamber 462, and the gas in the upper chamber 461 is discharged through the through hole 411, so as to facilitate the volume increase of the lower chamber 462.
When the volume of lower chamber 462 increases to the limit, i.e., lower chamber 462 cannot hold any more medical fluid, all of the medication drawn by powered pump 20 enters aerosolization mechanism 30 via second conduit 52.
When the medicine in the medicine source container 10 is completely sucked (the medicine is exhausted), the power pump 20 cannot suck the medicine from the medicine source container 10, at this time, the second conduit 52 is stopped by the on-off valve 70, as shown in fig. 5, the medicine in the lower chamber 462 with a certain pressure is supplied to the second conduit 52 and enters the atomizing mechanism 30 via the second conduit 52, the elastic dividing membrane 42 is continuously elastically retracted, the first spring 44 is continuously reset and extended, and the volume in the lower chamber 462 is reduced in the process that the medicine is continuously discharged from the lower chamber 462.
In order to reduce the pressure difference between the initial stage and the final stage of the medicine supply pressure in the lower chamber 462, that is, to make the supply pressure as stable as possible, the elastic modulus of the first spring 44 is made as small as possible, the compression degree is made as large as possible, and the elastic modulus of the elastic dividing membrane 42 is made as small as possible, so that the expansion and contraction process of the elastic dividing membrane 42 has a small influence on the medicine pressure, and the reaction force of the first spring 44 to the abutting block 43 changes little when expanding and contracting, so that the pressure change of the medicine in the lower chamber 462 is made small. In this way, when the variation in the supply pressure of the drug is small, the variation in the flow rate supplied to the atomizing mechanism 30 is also small, and the liquid drug having a stable flow rate can be supplied to the atomizing mechanism 30.
The advantages of the above embodiment are:
1. the supply pressure of the drug can be kept relatively constant throughout the supply process, i.e. the supply pressure is relatively constant, by setting the elastic coefficient of the first spring 44 and the elastic modulus of the elastic dividing membrane 42.
2. The resilient dividing membrane 42 is a flexible member that can be relaxed by the resilient dividing membrane 42 contracting on its own when there is a large fluctuation in the pressure of the drug entering the lower chamber 462 (which may be caused by a fluctuation in the operating power of the power pump 20).
In a preferred embodiment of the present invention, as shown in fig. 3, a dividing plate 45 is further disposed within lower chamber 462 for dividing lower chamber 462 into a first subchamber 4621 and a second subchamber 4622; wherein: the dividing plate 45 is provided with a first one-way valve 451 and a second one-way valve 452; an inlet and an outlet of the first one-way valve 451 are respectively communicated with the first sub-chamber 4621 and the second sub-chamber 4622; the inlet and outlet of second one-way valve 452 are in communication with second subchamber 4622 and first subchamber 4621, respectively. In this embodiment, when the power pump 20 is running, a portion of the drug first enters the first subchamber 4621 and then enters the second subchamber 4622 through the first one-way valve 451 for storage; when the power pump 20 is stopped, the drug stored in the second sub-chamber 4622 will be under pressure to open the second one-way valve 452, so that the drug enters the first sub-chamber 4621 and passes through the branch 53 and the second conduit 52 to the aerosolization mechanism 30.
In a preferred embodiment of the present invention, as shown in fig. 2 in combination with fig. 7, a flow rate limiting body 60 is disposed on the second conduit 52 between the branch 53 and the atomizing mechanism 30; the flow limiting body 60 is provided with a guiding hole 61, and the guiding hole 61 is used for limiting the flow of the medicine entering the atomizing mechanism 30 through the second conduit 52. That is, after the medicine flowing through the second conduit 52 passes through the diversion hole 61, the flow rate of the medicine is restricted by the diversion hole 61, and the flow rate of the medicine flowing out of the diversion hole 61 becomes small so that the supply amount of the medicine approximately corresponds to the required amount of the atomizing mechanism 30.
As already discussed, the reservoir mechanism 40 provided in the above embodiment can keep the supply pressure of the drug relatively stable by properly setting the elastic modulus of the first spring 44 and the elastic modulus of the elastic dividing membrane 42, however, the accuracy of the reservoir mechanism 40 in controlling the administration pressure is not so high because the pressure control manner of the reservoir mechanism 40 is open-loop control, i.e., control is not performed according to the actual pressure of the drug in the second conduit 52. So that it is difficult to supply the medicine to the atomizing mechanism 30 at a constant flow rate.
In order to solve the above problem, in a preferred embodiment of the present invention, as shown in fig. 2 and fig. 6, the supply branch 53 is further provided with a constant flow mechanism 80; the constant flow mechanism 80 controls the flow rate of the medicine flowing from the reservoir mechanism into the atomizing mechanism 30 according to the pressure of the medicine in the second conduit 52 between the flow rate limiting body 60 and the atomizing mechanism 30 so as to keep the flow rate of the medicine flowing into the atomizing mechanism 30 constant. Specifically, the constant current mechanism 80 includes: the holding body 81, the sliding core 82, the inlet bend 85, the outlet bend 86, the second spring 84, the first control channel 87, the second control channel 88 and the control line 54. Wherein, a sliding cavity is arranged in the holding body 81; the sliding core 82 is arranged in the sliding cavity and can slide along the sliding cavity, and the sliding core 82 divides the sliding cavity into a first closed cavity 831, a second closed cavity 832 and a diversion cavity 833 which is isolated from the first closed cavity 831 and the second closed cavity 832; the liquid inlet bend 85 penetrates from the outside of the holding body 81 to the diversion cavity 833, and the liquid inlet bend 85 is communicated with the lower cavity 462 (or called variable cavity) through the branch 53; the liquid outlet bend 86 penetrates from the outside of the holding body 81 to the flow guide cavity 833 to enable the medicine in the lower chamber 462 (or called variable chamber) to enter the liquid outlet bend 86 through the sliding cavity, the liquid outlet bend 86 is communicated with the second conduit 52 through the branch 53, thus, the liquid outlet bend 86 is communicated with the liquid inlet bend 85 through the flow guide cavity 833, and the second spring 84 is arranged in the second closed cavity 832 and used for pushing against the sliding core 82; the first control channel 87 is used for communicating the first closing cavity 831 with the outlet bend 86; a second control channel 88 passes from the outside of the retaining body 81 to the second closing chamber 832; the control line 54 is used to communicate the second conduit 52 between the atomizing mechanism 30 and the flow restrictor 60 to the second control passage 88. And: when the sliding core 82 slides towards the second closed cavity 832, the flow cross section of the liquid inlet bend 85 and the liquid outlet bend 86 can be reduced, and when the sliding core 82 slides towards the first closed cavity 831, the flow cross section of the liquid inlet bend 85 and the liquid outlet bend 86 can be increased. The relationship between the sliding direction of the sliding core 82 and the size of the flow cross section can be realized by the following structure: the sliding core 82 controls the opening 861 of the liquid outlet bend 86 penetrating to the wall of the diversion cavity 833 through sliding, when the sliding core 82 slides towards the second closed cavity 832, the opening 861 is reduced, and when the sliding core 82 slides towards the first closed cavity 831, the opening 861 is increased, so that the opening degree of the opening 861 forms a through-flow section through which the medicine flows through the diversion cavity.
The working process of the constant-current mechanism 80 when the liquid storage mechanism 40 supplies the medicine to the atomization mechanism 30 is as follows:
when the medicine in the medicine source container is used up, the power pump 20 stops running, and the liquid storage mechanism 40 supplies the medicine to the atomizing mechanism 30, the medicine in the lower chamber 462 flows out and enters the inlet bend 85, the medicine flows into the guide cavity 833 through the inlet bend 85 and flows through the guide cavity 833 into the outlet bend 86, and enters the second conduit 52 through the outlet bend 86, and after flowing through the guide hole 61 of the flow limiting body 60 in the second conduit 52, the medicine enters the atomizing mechanism 30, meanwhile, a part of the medicine flowing through the guide hole 61 enters the second closed cavity 832 through the control pipeline 54 as control liquid, and the medicine in the outlet bend 86 enters the first closed cavity 831 through the control channel. As such, when the pressure of the drug in the lower chamber 462 is unchanged, the sliding core 82 maintains a static state, and the second spring 84 and the drug in the second closed cavity 832 push the sliding core 82 equally to the drug in the first closed cavity 831.
When the pressure of the medicine in the lower chamber 462 increases due to some reason (for example, the housing 41 is acted and then suddenly moves upwards in an accelerated manner), the pressure of the medicine flowing through the liquid outlet curve 86 correspondingly increases, so that the pressure in the first closed cavity 831 increases, the balance of the sliding core 82 is broken, the sliding core 82 moves towards the second closed cavity 832, the opening 861 is reduced, the pressure of the medicine in the liquid outlet curve 86 can be reduced, the sudden increase of the flow rate caused by the sudden increase of the pressure is overcome, the pressure flowing through the liquid outlet curve 86, the second conduit 52 and the flow guide hole 61 cannot generate large rising fluctuation, and the flow rate flowing into the atomizing mechanism 30 cannot have large rising fluctuation.
Accordingly, when the pressure of the medicine in the lower chamber 462 is reduced due to some reason (for example, the housing 41 is acted to move suddenly and quickly downward), the sliding core 82 slides toward the first closing cavity 831, so that the pressure flowing through the liquid outlet bend 86, the second conduit 52 and the diversion hole 61 does not fluctuate greatly.
The above is directed at the working process of the constant flow mechanism 80 when the pressure is suddenly changed, and as can be seen from the above analysis, the constant flow mechanism 80 can effectively reduce the flow fluctuation caused by the pressure fluctuation to the medicine.
As can be seen from the above, the pressure of the drug supplied to the reservoir mechanism 40 is continuously reduced with the supply time, and the reduction range can be reduced by providing the elastic coefficient of the first spring 44, but since the reservoir mechanism 40 is not directly used to control the flow rate of the drug solution, but indirectly controls the pressure to stabilize the flow rate as much as possible, the reservoir mechanism 40 is difficult to satisfy the requirement when the requirement for the constant flow rate is high.
The constant flow mechanism 80 can meet the situation of high requirement on the drug flow, and from the overall analysis, when the sliding core 82 is stressed in a balanced manner, no matter where the sliding core 82 is located, the thrust of the drug in the first closed cavity 831 to the sliding core 82 is always equal to the thrust of the drug in the second closed cavity 832 to the sliding core 82 and the thrust of the second spring 84 to the sliding core 82. The pressure of the drug in the first closed cavity 831 is equal to the pressure of the drug before entering the diversion hole 61, and the pressure of the drug in the second closed cavity 832 is equal to the pressure of the drug flowing out of the diversion hole 61, so the difference between the two pressures is equal to the pressure difference between the two ends of the diversion hole 61, if the second spring 84 is selected as the spring with the elasticity coefficient as small as possible, so when the sliding core 82 is at different positions, the thrust of the second spring 84 to the sliding core 82 hardly changes, and thus the pressure difference between the two ends of the diversion hole 61 hardly changes. So that the flow through the baffle holes 61 is relatively constant and a relatively constant medicament can be provided to the nebulizer.
In a preferred embodiment of the present invention, as shown in fig. 2 in combination with fig. 7, an area of the inner wall of the diversion hole 61 is covered with an elastic bag 62, a plug 63 is arranged on the flow rate limiting body 60 in a penetrating way, and the plug 63 reduces the flow-through section of the medicine flowing through the diversion hole 61 by pushing against the elastic bag 62 to make the elastic bag 62 protrude out of the inner wall of the diversion hole; wherein: the flow rate limiting body 60 is also provided with a nut 65 coaxially opposite to the plug 63 on the outside; the opposite ends of the rotating nut 65 and the plug 63 are respectively provided with a magnet 64; the two magnets 64 are formed into a ring by butting two arc-shaped magnetic sections, the opposite magnetic poles of the two arc-shaped magnetic sections of each magnet 64 face the same direction, so that the relative overlapping degree of the same magnetic poles of the two magnets 64 is changed by rotating the rotating nut 65, the magnetic repulsion between the two magnets is changed, the degree of the plug 63 extending out of the flow guide hole 61 is changed, the degree of the elastic bag 62 protruding out of the flow guide hole 61 is changed, and finally the through-flow section limiting the flow of the medicine flowing through the flow guide hole 61 can be changed.
The advantages of the above embodiment are:
1. the flow cross-section of the flow directing holes 61 is variable, thereby regulating the flow of the drug entering the aerosolization mechanism 30 by varying the flow cross-section of the flow directing holes 61.
2. The two magnets 64 in this embodiment can change the magnetic repulsion between the two magnets only by relative rotation, while the magnets 64 on the left and right sides in the prior art can change the magnetic repulsion between the two magnets by changing the relative distance between the two magnets, so the way of changing the magnetic repulsion in this embodiment can save the installation space.
The above embodiments are only exemplary embodiments of the present invention, and are not intended to limit the present invention, and the scope of the present invention is defined by the claims. Various modifications and equivalents may be made by those skilled in the art within the spirit and scope of the present invention, and such modifications and equivalents should also be considered as falling within the scope of the present invention.