CN109172050A - The titanium plate and preparation method thereof of compound can be filled in a kind of Bioexperiment inside - Google Patents
The titanium plate and preparation method thereof of compound can be filled in a kind of Bioexperiment inside Download PDFInfo
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- CN109172050A CN109172050A CN201811113260.4A CN201811113260A CN109172050A CN 109172050 A CN109172050 A CN 109172050A CN 201811113260 A CN201811113260 A CN 201811113260A CN 109172050 A CN109172050 A CN 109172050A
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- titanium plate
- hole
- filling
- bioexperiment
- compound
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- RTAQQCXQSZGOHL-UHFFFAOYSA-N Titanium Chemical compound [Ti] RTAQQCXQSZGOHL-UHFFFAOYSA-N 0.000 title claims abstract description 123
- 239000010936 titanium Substances 0.000 title claims abstract description 123
- 229910052719 titanium Inorganic materials 0.000 title claims abstract description 123
- 150000001875 compounds Chemical class 0.000 title claims abstract description 22
- 238000002360 preparation method Methods 0.000 title claims abstract description 16
- 238000003754 machining Methods 0.000 claims abstract description 6
- 238000010146 3D printing Methods 0.000 claims abstract description 5
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 claims description 12
- 238000001514 detection method Methods 0.000 claims description 6
- 238000000227 grinding Methods 0.000 claims description 6
- 230000008676 import Effects 0.000 claims description 6
- 238000000034 method Methods 0.000 claims description 6
- 229910052757 nitrogen Inorganic materials 0.000 claims description 6
- 230000008569 process Effects 0.000 claims description 4
- 230000009471 action Effects 0.000 claims description 3
- 238000002347 injection Methods 0.000 claims description 3
- 239000007924 injection Substances 0.000 claims description 3
- 238000009700 powder processing Methods 0.000 claims description 3
- 238000012545 processing Methods 0.000 claims description 3
- 230000008439 repair process Effects 0.000 claims description 3
- 230000007547 defect Effects 0.000 claims description 2
- 239000000463 material Substances 0.000 abstract description 11
- 238000002513 implantation Methods 0.000 abstract description 9
- 239000007943 implant Substances 0.000 abstract description 5
- 241001465754 Metazoa Species 0.000 abstract description 3
- 239000004053 dental implant Substances 0.000 abstract description 2
- 238000007493 shaping process Methods 0.000 abstract description 2
- 239000000945 filler Substances 0.000 description 7
- 238000002474 experimental method Methods 0.000 description 5
- 238000004088 simulation Methods 0.000 description 3
- 239000002131 composite material Substances 0.000 description 2
- 238000013461 design Methods 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 239000002905 metal composite material Substances 0.000 description 2
- 239000012783 reinforcing fiber Substances 0.000 description 2
- 239000000523 sample Substances 0.000 description 2
- 238000007789 sealing Methods 0.000 description 2
- 238000004381 surface treatment Methods 0.000 description 2
- 229920001651 Cyanoacrylate Polymers 0.000 description 1
- 230000008901 benefit Effects 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 238000010276 construction Methods 0.000 description 1
- 230000008878 coupling Effects 0.000 description 1
- 238000010168 coupling process Methods 0.000 description 1
- 238000005859 coupling reaction Methods 0.000 description 1
- 230000003993 interaction Effects 0.000 description 1
- 239000006101 laboratory sample Substances 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000007639 printing Methods 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 230000001954 sterilising effect Effects 0.000 description 1
- 238000004659 sterilization and disinfection Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/28—Bones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61C—DENTISTRY; APPARATUS OR METHODS FOR ORAL OR DENTAL HYGIENE
- A61C8/00—Means to be fixed to the jaw-bone for consolidating natural teeth or for fixing dental prostheses thereon; Dental implants; Implanting tools
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B33—ADDITIVE MANUFACTURING TECHNOLOGY
- B33Y—ADDITIVE MANUFACTURING, i.e. MANUFACTURING OF THREE-DIMENSIONAL [3-D] OBJECTS BY ADDITIVE DEPOSITION, ADDITIVE AGGLOMERATION OR ADDITIVE LAYERING, e.g. BY 3-D PRINTING, STEREOLITHOGRAPHY OR SELECTIVE LASER SINTERING
- B33Y10/00—Processes of additive manufacturing
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B33—ADDITIVE MANUFACTURING TECHNOLOGY
- B33Y—ADDITIVE MANUFACTURING, i.e. MANUFACTURING OF THREE-DIMENSIONAL [3-D] OBJECTS BY ADDITIVE DEPOSITION, ADDITIVE AGGLOMERATION OR ADDITIVE LAYERING, e.g. BY 3-D PRINTING, STEREOLITHOGRAPHY OR SELECTIVE LASER SINTERING
- B33Y50/00—Data acquisition or data processing for additive manufacturing
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/28—Bones
- A61F2002/2835—Bone graft implants for filling a bony defect or an endoprosthesis cavity, e.g. by synthetic material or biological material
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2/30767—Special external or bone-contacting surface, e.g. coating for improving bone ingrowth
- A61F2/30771—Special external or bone-contacting surface, e.g. coating for improving bone ingrowth applied in original prostheses, e.g. holes or grooves
- A61F2002/30772—Apertures or holes, e.g. of circular cross section
- A61F2002/30784—Plurality of holes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2/3094—Designing or manufacturing processes
- A61F2002/30985—Designing or manufacturing processes using three dimensional printing [3DP]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2310/00—Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
- A61F2310/00005—The prosthesis being constructed from a particular material
- A61F2310/00011—Metals or alloys
- A61F2310/00023—Titanium or titanium-based alloys, e.g. Ti-Ni alloys
Abstract
The invention discloses the titanium plates and preparation method thereof that compound can be filled inside a kind of Bioexperiment, the titanium plate is cylindrical structure, the titanium plate is equipped with the first porous structure, first porous structure includes multiple vertical holes, the vertical hole is deep into inside titanium plate from a side end face of titanium plate, the titanium plate is equipped with the second porous structure, second porous structure includes multiple filling through-holes, the filling through-hole runs through titanium plate side wall, and the filling through-hole is parallel to titanium plate end face.It is equipped with filling through-hole in heretofore described titanium plate, the compound of various dose, unlike material can be filled in filling through-hole, therefore heretofore described titanium plate is able to carry out the implantation material Bioexperiment of polymorphic type.Heretofore described titanium plate 3D printing rapid shaping improves the preparation rate and machining accuracy of titanium plate.The present invention is for Bioexperiment such as cell, the animals of orthopaedics implant or dental implant.
Description
Technical field
The invention belongs to the field of medical instrument technology, more particularly to it is a kind of for orthopaedics implant or dental implant materials,
The titanium plate of the Bioexperiment such as cell, the animal of the properties such as structure, configuration of surface.
Background technique
At present in dentistry and field of orthopaedics, obtained by the composite implant of granulated filler or reinforcing fiber and metal composite
It must popularize.But the implantation material currently used for implantation material Bioexperiment generallys use pure titanium plate, using pure titanium plate into
Row experiment can effectively simple flow and reduce laboratory sample cost of manufacture, but pure titanium plate be solid construction, only
It can be carried out surface treatment, therefore pure titanium plate can only pass through the surface of surface treatment simulation implantation material.It carries out by graininess
The implantation Bioexperiment of filler or the composite implant of reinforcing fiber and metal composite then needs to carry out a large amount of implantation material sample
Preparation, this can greatly increase experimental cost and experimental period.
Summary of the invention
The present invention provides the titanium plate and preparation method thereof that compound can be filled inside a kind of Bioexperiment, in the present invention
It is equipped with filling through-hole in the titanium plate, the compound of various dose, unlike material can be filled in filling through-hole, therefore
Heretofore described titanium plate is able to carry out the implantation material Bioexperiment of polymorphic type, and heretofore described porous using 3D
The preparation method of printing improves its preparation efficiency and machining accuracy.
To achieve the above object, the present invention uses following technological means.
The titanium plate of compound can be filled in a kind of Bioexperiment inside, and the titanium plate is cylindrical structure, described more
Hole titanium sheet is equipped with the first porous structure, and first porous structure includes multiple vertical holes, and the vertical hole is from titanium plate
A side end face be deep into inside titanium plate, the second porous structure, the second porous knot are additionally provided on the titanium plate
Structure includes multiple filling through-holes, and the filling through-hole runs through titanium plate side wall, and the filling through-hole is parallel to POROUS TITANIUM bit end
Face.
Further, the filling through-hole is connected to vertical hole, filling through-hole be connected to vertical hole can with Fast Filling, and
So that filler is distributed in the end face of titanium plate, change the configuration of surface of titanium plate.
Further, the vertical hole is radially distributed.
Further, the filling through-hole passes through the central axes of titanium plate, and the angle between adjacent filling through-hole is
60°。
Further, the diameter of the titanium plate is 5~15mm, with a thickness of 1~5mm, the spacing of adjacent two vertical hole
For 0.5~1.5mm, the diameter of the vertical hole is 0.3~0.9mm, and the diameter of the filling through-hole is 1~2mm.
A kind of preparation method of the titanium plate of the fillable compound in Bioexperiment inside, comprising the following steps:
(1) by three-dimensional drawing software design titanium plate structure, saving output is STL formatted file, action when output
It is set as minimum；
(2) the resulting STL formatted file of step (1) is imported in Magics software and carries out error detection and repairs；
(3) file after repairing step (2) imports in the dedicated Slice Software of SLM 3D printer, by need to print
Titanium plate model carries out the adjustment of position, so that each titanium plate model is vertically arranged, i.e. the disc of titanium plate model
It is vertical with the real estate for entering SLM 3D printer, then titanium plate model is increased, and by two neighboring filling through-hole it
Between entity part covering, then by titanium plate model carry out slicing treatment, finally save output；
(4) file by step (3) output imports in 3D printer, processing stations is adjusted, so that each titanium plate mould
Type is arranged along the direction of powdering, and nitrogen protection is needed during 3D printing, and
Machining accuracy≤0.025mm；
(5) the resulting titanium plate of step (4) is subjected to clear powder processing, the nitrogen injection of pressurization is filled in through-hole, it will
Fill the titanium valve blowout in through-hole；
(6) part that will be completed between two filling through-holes of the titanium plate of step (5) carries out grinding process, removes coarse lack
It falls into；
(7) the filling through-hole for the titanium plate for completing step (6) is surface-treated.
Further, the preparation method of the titanium plate of compound can be filled inside a kind of Bioexperiment, step (7) is gone back afterwards
Comprising steps of
(8) the unobstructed of filling through-hole detection filling through-hole is irradiated by light.
Further, the preparation method of the titanium plate of compound can be filled in a kind of Bioexperiment inside, further includes, to system
The titanium plate obtained is cleaned by ultrasonic and is sterilized.
The invention has the benefit that filling through-hole is equipped in heretofore described titanium plate, it can in filling through-hole
To fill the compound of various dose, unlike material, therefore heretofore described titanium plate is able to carry out the implantation of polymorphic type
Object Bioexperiment；The end face of heretofore described titanium plate is also equipped with the first porous structure, the first porous structure packet
Multiple vertical holes are included, the vertical hole is deep into inside titanium plate from a side end face of titanium plate, and such design can
Effective simulation porous implant porous surface form；And it is equipped with filling through-hole, a variety of fill out can be filled into filling through-hole
Object is filled, the Bioexperiment of the implantation material of different volumes compound is inlayed in simulation, therefore expands heretofore described titanium plate
Use scope；Heretofore described titanium plate can quickly and easily manufacture this by SLM technology 3D printing rapid shaping
Titanium plate described in invention, and heretofore described preparation method advantageously ensure that the machining accuracy of titanium plate with
And guarantee the titanium plate various structures hole in titanium valve removing.
Detailed description of the invention
Fig. 1 is the top view of heretofore described titanium plate.
Fig. 2 is the front view of heretofore described titanium plate.
Fig. 3 is the sectional view in the direction A-A in the present invention.
Specific embodiment
It is carried out below with reference to technical effect of the embodiment and attached drawing to design of the invention, specific structure and generation clear
Chu is fully described by, to be completely understood by the purpose of the present invention, feature and effect.Obviously, described embodiment is this hair
Bright a part of the embodiment, rather than whole embodiments, based on the embodiment of the present invention, those skilled in the art are not being paid
Other embodiments obtained, belong to the scope of protection of the invention under the premise of creative work.In addition, be previously mentioned in text
All connection/connection relationships not singly refer to that component directly connects, and referring to can be added deduct according to specific implementation situation by adding
Few couple auxiliary, to form more preferably coupling structure.Each technical characteristic in the invention, in not conflicting conflict
Under the premise of can be with combination of interactions.
Referring to Fig.1~3, the titanium plate of compound can be filled inside a kind of Bioexperiment, the titanium plate is cylinder
Structure, the titanium plate are equipped with the first porous structure, and first porous structure includes multiple vertical holes 11, described vertical
Hole 11 is deep into inside titanium plate from a side end face of titanium plate, and the second porous structure is additionally provided on the titanium plate,
Second porous structure includes multiple filling through-holes 21, and the filling through-hole 21 runs through titanium plate side wall, and the filling is logical
Hole 21 is parallel to titanium plate end face.
Further, the filling through-hole 21 is connected to vertical hole 11.
Further, the vertical hole 11 is radially distributed.
Further, the filling through-hole 21 passes through the central axes of hole titanium sheet, and the angle between adjacent filling through-hole 21
It is 60 °.
Further, the diameter of the titanium plate is 10mm, and with a thickness of 2mm, the spacing of adjacent two vertical hole 11 is
1mm, the diameter of the vertical hole 11 are 0.6mm, and the diameter of the filling through-hole 21 is 1.5mm.
A kind of preparation method of the titanium plate of the fillable compound in Bioexperiment inside, comprising the following steps:
(1) by three-dimensional drawing software design titanium plate structure, saving output is STL formatted file, action when output
It is set as minimum；
(2) the resulting STL formatted file of step (1) is imported in Magics software and carries out error detection and repairs；
(3) file after repairing step (2) imports in the dedicated Slice Software of SLM 3D printer, by need to print
Titanium plate model carries out the adjustment of position, so that each titanium plate model is vertically arranged, i.e. the disc of titanium plate model
It is vertical with the real estate for entering SLM 3D printer, then titanium plate model is increased, and by two neighboring filling through-hole 21
Between entity part covering, then by titanium plate model carry out slicing treatment, finally save output；
(4) file by step (3) output imports in 3D printer, processing stations is adjusted, so that each titanium plate mould
Type is arranged along the direction of powdering, and nitrogen protection, and machining accuracy≤0.025mm are needed during 3D printing；
(5) the resulting titanium plate of step (4) is subjected to clear powder processing, the nitrogen injection of pressurization is filled in through-hole 21,
The blowout of the titanium valve in through-hole 21 will be filled；
(6) part that will be completed between two filling through-holes 21 of the titanium plate of step (5) carries out grinding process, removes coarse
Defect；
(7) the filling through-hole 21 for the titanium plate for completing step (6) is surface-treated；
(8) the unobstructed of the filling detection filling through-hole 21 of through-hole 21 is irradiated by light；
(9) titanium plate for completing step (8) is cleaned by ultrasonic and is sterilized, POROUS TITANIUM of the present invention is made
Piece.
The specific operation process that heretofore described titanium plate is filled are as follows: be ready to that sterilization treatment crosses fills out
Fill object, guarantee the partial size of filler in 1.5mm hereinafter, simultaneously at the same guarantee filler be molten condition or powdered, pay attention to filling out
Filling object cannot be liquid.Ready filler is filled into the filling through-hole of the titanium plate, filler is exposed at
The part of outside is filled with by the method that machinery taps into filling through-hole.Then titanium plate is clamped by tweezers
At disc center, and titanium plate is erect and is placed, drawn a-cyanoacrylate using syringe and dripped in filling cavity knot
At structure, rotation titanium plate carries out the sealing of next cavity after it air-dries sealing.Prepare the titanium plate sample of experiment
After product, require to be tested according to specific experiments, such as: it needs the titanium plate prepared being put into hole if it is cell experiment
Cell experiment is carried out in plate, then needs for titanium plate to be implanted into animal body if it is zoopery.
Better embodiment of the invention is illustrated above, but the invention is not limited to the implementation
Example, those skilled in the art can also make various equivalent modifications on the premise of without prejudice to spirit of the invention or replace
It changes, these equivalent variation or replacement are all included in the scope defined by the claims of the present application.
Claims (8)
1. the titanium plate of compound can be filled inside a kind of Bioexperiment, which is characterized in that the titanium plate is cylinder knot
Structure, the titanium plate are equipped with the first porous structure, and first porous structure includes multiple vertical holes, the vertical hole from
One side end face of titanium plate is deep into inside titanium plate, is additionally provided with the second porous structure on the titanium plate, and described
Two porous structures include multiple filling through-holes, and the filling through-hole runs through titanium plate side wall, and the filling through-hole is parallel to more
Hole titanium sheet end face.
2. the titanium plate of compound can be filled inside a kind of Bioexperiment according to claim 1, which is characterized in that institute
Filling through-hole is stated to be connected to vertical hole.
3. the titanium plate of compound can be filled inside a kind of Bioexperiment according to claim 1, which is characterized in that institute
Vertical hole is stated radially to be distributed.
4. the titanium plate of compound can be filled inside a kind of Bioexperiment according to claim 1, which is characterized in that institute
The central axes that filling through-hole passes through titanium plate are stated, and the angle between adjacent filling through-hole is 60 °.
5. the titanium plate of compound can be filled inside a kind of Bioexperiment according to claim 1, which is characterized in that institute
The diameter for stating titanium plate is 5~15mm, and with a thickness of 1~5mm, the spacing of adjacent two vertical hole is 0.5~1.5mm, described to hang down
The diameter of straight hole is 0.3~0.9mm, and the diameter of the filling through-hole is 1~2mm.
6. the preparation method of the titanium plate of compound can be filled inside a kind of Bioexperiment, which is characterized in that including following step
It is rapid:
(1) by three-dimensional drawing software design titanium plate structure, saving output is STL formatted file, and action is set as when output
Minimum；
(2) the resulting STL formatted file of step (1) is imported in Magics software and carries out error detection and repairs；
(3) file after repairing step (2) imports in the dedicated Slice Software of SLM 3D printer, will need to print porous
Titanium sheet model carries out the adjustment of position so that each titanium plate model is vertically arranged, i.e., the disc of titanium plate model with enter
The real estate of SLM 3D printer is vertical, then increases titanium plate model, and will be between two neighboring filling through-hole
Entity part covering, then carries out slicing treatment for titanium plate model, finally saves output；
(4) file by step (3) output imports in 3D printer, processing stations is adjusted, so that each titanium plate model edge
Powdering direction arrangement, nitrogen protection, and machining accuracy≤0.025mm are needed during 3D printing；
(5) the resulting titanium plate of step (4) is subjected to clear powder processing, by the nitrogen injection filling through-hole of pressurization, will filled
Titanium valve blowout in through-hole；
(6) part that will be completed between two filling through-holes of the titanium plate of step (5) carries out grinding process, removes coarse defect；
(7) the filling through-hole for the titanium plate for completing step (6) is surface-treated.
7. the preparation method of the titanium plate of compound can be filled inside a kind of Bioexperiment according to claim 6,
It is characterized in that, step further comprises the steps of: after (7)
(8) the unobstructed of filling through-hole detection filling through-hole is irradiated by light.
8. the preparation method of the titanium plate of compound can be filled inside a kind of Bioexperiment of according to claim 6 or 7, it is special
Sign is, titanium plate obtained is cleaned by ultrasonic and is sterilized.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201811113260.4A CN109172050A (en) | 2018-09-21 | 2018-09-21 | The titanium plate and preparation method thereof of compound can be filled in a kind of Bioexperiment inside |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201811113260.4A CN109172050A (en) | 2018-09-21 | 2018-09-21 | The titanium plate and preparation method thereof of compound can be filled in a kind of Bioexperiment inside |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN109172050A true CN109172050A (en) | 2019-01-11 |
Family
ID=64909574
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201811113260.4A Pending CN109172050A (en) | 2018-09-21 | 2018-09-21 | The titanium plate and preparation method thereof of compound can be filled in a kind of Bioexperiment inside |
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| Country | Link |
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| CN (1) | CN109172050A (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111085667A (en) * | 2019-12-30 | 2020-05-01 | 清华大学 | Design method of smooth inner cavity of hollow casting mold or hollow sand core |
| CN113081396A (en) * | 2019-12-23 | 2021-07-09 | 宝山钢铁股份有限公司 | Skull repairing material and preparation method thereof |
| WO2021169062A1 (en) * | 2020-02-27 | 2021-09-02 | 广州市健齿生物科技有限公司 | Repairing titanium mesh for use in alveolar bone grafting and manufacturing method for the mesh |
Citations (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1850293A (en) * | 2006-04-26 | 2006-10-25 | 卢建熙 | Medical reinforced porous biological ceramic, its preparing method and use |
| CN104212993A (en) * | 2014-07-24 | 2014-12-17 | 昆明理工大学 | Preparation method of porous titanium alloy material |
| CN104334092A (en) * | 2012-05-04 | 2015-02-04 | 西-博恩公司 | Fenestrated implant |
| CN104928517A (en) * | 2015-06-24 | 2015-09-23 | 南华大学 | Preparing method of porous magnesium-based hydroxyapatite composite and material prepared thereby |
| CN105147423A (en) * | 2015-08-04 | 2015-12-16 | 天津理工大学 | Preparation method of tissue engineering scaffold with three-dimensional composite porous structure |
| CN107303207A (en) * | 2016-04-20 | 2017-10-31 | 重庆润泽医药有限公司 | A kind of porous metals rod |
| CN107349472A (en) * | 2017-06-30 | 2017-11-17 | 浙江德康医疗器械有限公司 | A kind of preparation method of the gradient porous titanium alloy of repetition of promotion bone fusion |
| CN209316151U (en) * | 2018-09-21 | 2019-08-30 | 广州市健齿生物科技有限公司 | The titanium plate of compound can be filled in a kind of Bioexperiment inside |
-
2018
- 2018-09-21 CN CN201811113260.4A patent/CN109172050A/en active Pending
Patent Citations (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1850293A (en) * | 2006-04-26 | 2006-10-25 | 卢建熙 | Medical reinforced porous biological ceramic, its preparing method and use |
| CN104334092A (en) * | 2012-05-04 | 2015-02-04 | 西-博恩公司 | Fenestrated implant |
| CN104212993A (en) * | 2014-07-24 | 2014-12-17 | 昆明理工大学 | Preparation method of porous titanium alloy material |
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