CN109171811A - The passive cavitation imaging of frequency domain and frequency multiplexed imaging method based on the synthesis of feature space adaptive beam - Google Patents

The passive cavitation imaging of frequency domain and frequency multiplexed imaging method based on the synthesis of feature space adaptive beam Download PDF

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CN109171811A
CN109171811A CN201811115045.8A CN201811115045A CN109171811A CN 109171811 A CN109171811 A CN 109171811A CN 201811115045 A CN201811115045 A CN 201811115045A CN 109171811 A CN109171811 A CN 109171811A
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cavitation
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万明习
路舒宽
李任晏
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Xian Jiaotong University
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Abstract

The present invention provides a kind of passive cavitation imaging of frequency domain based on the synthesis of feature space adaptive beam and frequency multiplexed imaging methods, make Fourier transformation to time domain cavitation signal and carry out phase offset and array element apodization processing;Covariance matrix is constructed, the weight vectors of adaptive beam synthesis are obtained according to normalization steering vector and covariance matrix;Feature Space Decomposing is carried out to covariance matrix, weight vectors are projected to after signal subspace to the passive cavitation imaging for carrying out full frequency-domain;It constructs the passive cavitation imaging results of full frequency-domain that cavitation artifact is not known than index and according to different steering vectors under collection parameter and selects the uncertain collection parameter of optimal steering vector, to realize that the passive cavitation of different sub- frequency domains is imaged and frequency multiplexed is imaged.The present invention can significantly inhibit imaging artefacts, to improve the spatial discrimination performance of the passive cavitation imaging of frequency domain, can any number of frequency contents be carried out with comprehensive fixed sign, suitable for the real time monitoring of a variety of focused ultrasound therapies application.

Description

The passive cavitation imaging of frequency domain and frequency based on the synthesis of feature space adaptive beam are multiple Synthesized image method
Technical field
The invention belongs to ultrasound detections and ultrasonic imaging technique field, and in particular to one kind is based on the adaptive wave of feature space The passive cavitation imaging of the frequency domain of Shu Hecheng and frequency multiplexed imaging method.
Background technique
In ultrasound in medicine and biology field, ultrasonic cavitation is had been a hot spot of research, and in tumour heating ablation, external stone crushing, is surpassed The focused ultrasound therapies such as sound thrombolysis and drug release cavitation has all served vital.It is empty in tumour heating ablation Focused ultrasound beams formation can be blocked to influence focusing performance by changing microvesicle, caused damage field unpredictable, reduced treatment Accuracy;And the sound thermal conversion efficiency of tissue can be improved in another aspect cavitation, thus when reducing treatment energy and shortening treatment Between.In rubble, the energy that discharges generates in regional area when cavitation microvesicle moment collapses high temperature, high pressure, shock wave and The physical phenomenons such as jet stream accelerate the broken of calculus.In ultrasound thrombolysis, the high rapid fire of cavitation vibrating microbubbles and rupture generation Stream and shock wave etc. can effectively decompose thrombus, to improve thrombolysis efficiency.However due to the uncontrollability of cavitation and at random Property, may normal tissue form irreversible damage, therapeutic purposes are not achieved.Even in addition, studies have shown that examining Under disconnected ultrasound acoustic pressure, the shearing force and jet stream that cavitation microvesicle is formed can also generate biological effect to peripheral cell or tissue, thus Generate the risk of injury of blood vessel and rupture.Therefore efficiently control and using cavitation for focused ultrasound therapy scheme regulation with Optimize important in inhibiting, and to realize this point and then have to the development dependent on cavitation detection technique.
In recent years, cavitation detection technique has developed to two dimension from one-dimensional, utilization clinically common linear array and phased array etc. Ultrasonic diagnostic transducer, which can be realized, determines sign to cavitation spatial distribution.Traditional B-mode ultrasonic imaging, plane wave have been developed at present Supper-fast ultrasonic imaging and the ultrasound gradually actives such as scanning imagery cavitation imaging method based on timing control, pass through and adjust hair Emission mode improves imaging algorithm performance simultaneously can realize high contrast and the imaging of high-resolution cavitation.However, due to focusing Active cavitation can be imaged during ultrasonic therapy and generate strong interference, therefore can only select to stop making completely in focusing ultrasound With being imaged later or before focusing ultrasonic pulse next time and not arriving also, and just due to this point, the imaging of active cavitation The cavitation microvesicle for focusing and generating when ultrasound does not act on can only be detected, and cannot detect and focus what ultrasonication generated in the process Cavitation behavior cannot also realize the real time monitoring imaging of focused ultrasound therapy.In order to make up the deficiency of active cavitation imaging, closely There is scholar to propose a kind of passive cavitation imaging method over year, this method only passively receives cavitation signal due to not emitting, Not by the interference of focus ultrasound signals, so as to realize that the effective of focused ultrasound therapy process cavitation determines sign.Passive cavitation Imaging has been used for monitoring tissue heating ablation, tissue ablation, drug release and Blood Brain Barrier (BBB) opening etc..It is most popular at present And most common passive cavitation imaging method is to carry out in the time domain, have later scholar propose the passive cavitation of frequency domain at Picture.Compared to time domain passive cavitation imaging, the passive cavitation imaging of frequency domain can directly frequency domain selection imaging object be stable cavitation or It is inertial cavitation, the band information only selected does Beam synthesis, therefore can reduce calculation amount compared to time domain approach;In addition, The imaging of frequency domain passive cavitation directly by the time delays of Fourier transformation realization signal, can to avoid due to low sampling rate from Dissipate delay time error caused by time sampling.However the passive cavitation imaging method of traditional frequency domain is that one kind is disobeyed intrinsically Rely the blind beam synthesizing method in data self character, will cause extremely serious imaging artefacts, image quality is bad, Bu Nengti Altitude sterically defined precision, therefore it is unfavorable for the real time monitoring of focused ultrasound therapy process.Therefore how high score is realized The passive cavitation imaging of the frequency domain of resolution is a major challenge of this field, and needs overcome difficult point.
Summary of the invention
The purpose of the present invention is to provide a kind of passive cavitation imagings of frequency domain based on the synthesis of feature space adaptive beam And frequency multiplexed imaging method.
To achieve the goals above, the invention adopts the following technical scheme:
A kind of passive cavitation imaging method of frequency domain based on the synthesis of feature space adaptive beam, comprising the following steps:
Step 1: passively receiving cavitation radiofrequency signal by ultrasonic imaging energy converter, carries out Fourier to cavitation radiofrequency signal Transformation obtains frequency domain cavitation signal, utilizes normalization cosine apodization function progress after making phase offset processing to frequency domain cavitation signal Apodization processing obtains the frequency domain cavitation letter after phase offset and array element apodization processing of all array elements of ultrasonic imaging energy converter Number;
Step 2: empty according to the frequency domain after phase offset and array element apodization processing of the resulting all array elements of step 1 Change signal and construct covariance matrix, is synthesized using the covariance matrix and the uncertain collection parameter building adaptive beam of steering vector Cost function, Lagrange's multiplier is introduced by constraint condition to the cost function and constructs Ge Lang constraint function, it is right Lagrangian constraint function derivation and to enable derived function be zero, obtains steering vector expression formula, steering vector expression formula is substituted into institute It states in the constraint condition of cost function and solves to obtain Lagrange's multiplier using Newton iteration method, the glug obtained according to solution Bright day multiplier calculates steering vector and steering vector is simultaneously made normalized, according to steering vector after normalized and described Covariance matrix obtains the weight vectors of adaptive beam synthesis;
Step 3: carrying out Feature Space Decomposing to the covariance matrix, obtain signal subspace, and step 2 is resulting The weight vectors of adaptive beam synthesis project on signal subspace, resulting to step 1 using the weight vectors after projection The frequency domain cavitation signal after phase offset and array element apodization processing of all array elements is weighted summation, then removes direct current Component obtains the output signal of feature space adaptive beam synthesis;To the output signal of feature space adaptive beam synthesis Progress square is simultaneously overlapped on entire frequency domain, obtains the passive cavitation imaging results of full frequency-domain;
Step 4: it according to cavitation artifact than selecting optimal steering vector is uncertain to collect parameter, is sweared according to optimal guiding The optimal output signal of the uncertain collection parameter determining features spatially adaptive Beam synthesis of amount;Exist respectively to the optimal output signal It is overlapped on the sub- frequency domain of difference in entire frequency domain, obtains the passive cavitation imaging results of different sub- frequency domains.
A kind of passive cavitation frequency multiplexed imaging method based on the synthesis of feature space adaptive beam, including following step It is rapid:
Step 1: Step 2: step 3 and step 4 are identical as the passive cavitation imaging method of above-mentioned frequency domain;
Step 5: standardization is done to the passive cavitation imaging results of the sub- frequency domain of difference, then by two of them The above sub- frequency domain is overlapped by the passive cavitation imaging results of standardization, obtains passive cavitation frequency multiplexed imaging As a result.
Above-mentioned steps one, specifically includes the following steps:
1.1) time domain cavitation signal is passively received using ultrasonic imaging energy converter, the time domain cavitation signal refers to that focusing is super The cavitation radiofrequency signal scattered at sonic transducer focal regions;
1.2) Fourier transformation is carried out to the time domain cavitation signal that i-th of array element of ultrasonic imaging energy converter receives, obtained Frequency domain cavitation signal:
Wherein, i=1,2 ..., N, N are ultrasonic imaging transducer array element number, t1It is the beginning for acquiring time domain cavitation signal Moment, t2It is the stop timing for acquiring time domain cavitation signal, j is imaginary unit, pi(t, x, z) be i-th of array element receive when Domain cavitation signal, f indicate frequency;
1.3) phase offset processing is carried out to frequency domain cavitation signal obtained by step 1.2):
Wherein, pofi(f, x, z) is the phase offset of i-th of array element;
1.4) array element apodization processing is carried out to the resulting phase offset of step 1.3) treated frequency domain cavitation signal:
Wherein, Apodi(f, x, z) is the normalization cosine apodization function of i-th of array element;
1.5) step 1.2)~1.4 are repeated), the process phase offset of N number of array element until obtaining ultrasonic imaging energy converter With the frequency domain cavitation signal after array element apodization processing.
Above-mentioned steps two, specifically includes the following steps:
2.1) the frequency domain cavitation after phase offset and array element apodization processing of the resulting all array elements of step 1 is utilized Signal constructs covariance matrix R:
Wherein, S (f, x, z)=[S1(f,x,z);S2(f,x,z);...;SN(f, x, z)] be ultrasonic imaging energy converter N The frequency domain cavitation signal matrix after phase offset and array element apodization processing of a array element,It indicates for arbitrary frequency f;
2.2) cost function of the building adaptive beam synthesis of covariance matrix obtained by step 2.1) is utilized:
Wherein, a is the steering vector to be solved,For the steering vector of hypothesis, | | | | Euclid norm is represented,For constraint condition, ε is the uncertain collection parameter of steering vector;
2.3) it after step 2.2), introduces Lagrange's multiplier and constructs Lagrangian constraint function:
Wherein, λ is Lagrange's multiplier;
2.4) the resulting Lagrangian constraint function of step 2.3) to steering vector a derivation and is enabled into derived function obtained by derivation It is zero, then utilizes matrix inversion lemma, obtain steering vector expression formula:
Wherein, I is unit matrix;
2.5) the resulting steering vector expression formula of step 2.4) is substituted into the constraint item of the resulting cost function of step 2.2) In part, then constraint condition is rewritten are as follows:
2.6) by the Feature Space Decomposing of the resulting covariance matrix R of step 2.1) to the resulting constraint item of step 2.5) Part is converted, then the lagrangian multiplier in constraint condition after conversion is then solved using Newton iteration method is passed through The resulting steering vector expression formula of step 2.4) calculates steering vector, and does normalized, obtains normalization steering vector
2.7) it is calculated certainly according to the resulting normalization steering vector of step 2.6) and the resulting covariance matrix R of step 2.1) Adapt to the weight vectors w of Beam synthesis:
Above-mentioned steps three, specifically includes the following steps:
3.1) empty to the frequency domain after phase offset and array element apodization processing of all array elements obtained according to step 1 Change covariance matrix constructed by signal and carry out Feature Space Decomposing:
R=U Λ UH=RS+RI
Wherein, U=[u1,u2,...,uN] it is characterized vector matrix, Λ=diag [γ12,...,γN] it is to angular moment Battle array, the matrix diagonals element are characterized value, and γ1≥γ2≥...≥γN, RSFor the covariance matrix of signal subspace, RIFor The covariance matrix of noise subspace;
3.2) weight vectors that adaptive beam synthesizes are projected into signal subspace, the weight vectors after being projected
Wherein, To normalize steering vector, US=[u1,u2,...,uL] it is preceding L larger characteristic values The signal subspace that corresponding feature vector is constituted, ΛS=diag [γ12,...,γL] be signal subspace characteristic value Matrix, diag [] indicate the diagonalization of vector;L is characterized the number of all characteristic values in value greater than δ times of maximum eigenvalue, δ is 0.2~0.5;
3.3) empty using the frequency domain after phase offset and array element apodization processing of each array element of ultrasonic imaging energy converter Weight vectors after changing signal and the resulting projection of step 3.2) calculate the weighted frequency domain cavitation signal of each array element:
Wherein,For the weight vectors after the resulting projection of step 3.2)I-th of element, Si(f, x, z) is ultrasound The frequency domain cavitation signal after phase offset and array element apodization processing of i-th of array element of imaging transducer, wherein i=1, 2 ..., N, N are ultrasonic imaging transducer array element number;
3.4) the weighted frequency domain cavitation signal of the N number of array element of ultrasonic imaging energy converter is overlapped, obtain signal Q (f, x, Z):
3.5) DC component is got rid of from signal Q (f, x, z) obtained by step 3.4), then obtains the adaptive wave of feature space The output signal of Shu HechengIt is rightCarry out square simultaneously be overlapped on entire frequency domain, obtain it is each at The energy of image position (x, z):
Wherein,It indicates for arbitrary frequency f.
Above-mentioned steps four, specifically includes the following steps:
4.1) cavitation artifact of the construction based on average energy is than index CAR:
CAR=20log10(ImeanCav/ImeanArt)
Wherein, ImeanCavFor cavitation zone or the average energy of cavitation zone selected part, ImeanArtFor artifact region or puppet The average energy of shadow zone domain selected part, the unit of CAR are dB;
4.2) portion is difference selected with artifact region according to cavitation zone and the cavitation artifact ratio or cavitation zone of artifact region The mean value of the cavitation artifact ratio divided, evaluates the passive cavitation image quality of full frequency-domain under different ε, and ε is the uncertain collection of steering vector Parameter, and choose the corresponding ε when CAR or CAR mean value highest and do not know to collect parameter as optimal steering vector, according to optimal The uncertain collection parameter of steering vector obtain the optimal output signal of feature space adaptive beam synthesisIts In, the traversal range of ε is 0.01~N, and traversal step-length is 0.01~1;
4.3) different sub- frequency domains is selected, the optimal output to the synthesis of step 4.2) resulting feature space adaptive beam Signal is overlapped respectively in different sub- frequency domains, then obtains the passive cavitation imaging of different sub- frequency domains:
Wherein, FR indicates given a certain sub- frequency domain, f1For the lower-frequency limit of the sub- frequency domain, f2For the frequency of the sub- frequency domain The upper limit.
Above-mentioned steps five, specifically includes the following steps:
5.1) the passive cavitation imaging results of the sub- frequency domain of difference resulting to step 4 are standardized, and are then carried out Superposition, obtains passive cavitation frequency multiplexed imaging results:
Wherein, NFR is the sub- frequency domain number for participating in frequency multiplexed imaging,To participate in frequency multiplexed imaging The passive cavitation imaging results of i-th of sub- frequency domain after standardization.
A kind of passive cavitation imaging system of frequency domain based on the synthesis of feature space adaptive beam, including phase offset and battle array First apodization processing module, adaptive beam synthesize the passive cavitation image-forming module and son of weight vectors computing module, full frequency-domain The passive cavitation image-forming module of frequency domain;The phase offset and array element apodization processing module are for executing above-mentioned steps one;It is described Adaptive beam synthesis weight vectors computing module is for executing above-mentioned steps two;The passive cavitation image-forming module of the full frequency-domain For executing above-mentioned steps three;The passive cavitation image-forming module of the sub- frequency domain is for executing above-mentioned steps four.
A kind of passive cavitation frequency multiplexed imaging system based on the synthesis of feature space adaptive beam, including above-mentioned phase Offset and array element apodization processing module, above-mentioned adaptive beam synthesize the passive sky of weight vectors computing module, above-mentioned full frequency-domain Change the passive cavitation image-forming module and passive cavitation frequency multiplexed image-forming module of image-forming module, above-mentioned sub- frequency domain;It is described passive Cavitation frequency multiplexed image-forming module is for executing above-mentioned steps five.
The beneficial effects of the present invention are embodied in:
The present invention is directed to the passive cavitation imaging method of traditional frequency domain existing defect in terms of monitoring focused ultrasound therapy, leads to It crosses and phase offset and array element apodization processing is carried out to frequency domain cavitation signal and construct the covariance matrix of frequency domain, building frequency domain is certainly The cost function for adapting to Beam synthesis acquires the weight vectors of adaptive beam synthesis on this basis;Then by weight vectors The covariance matrix of frequency domain is projected to through the weight vectors on the resulting signal subspace of Feature Space Decomposing, and after use projection Beam synthesis is carried out, effective inhibition has been carried out to imaging artefacts, improves the space point of the different passive cavitation imagings of sub- frequency domain It distinguishes performance, has great significance for the real time monitoring of focused ultrasound therapy process cavitation.
The present invention is based on the passive cavitation imagings of the sub- frequency domain of high-resolution performance, by the passive cavitation imaging results of sub- frequency domain It is standardized and superposition realizes passive cavitation frequency multiplexed imaging, further improve image quality.
Detailed description of the invention
Fig. 1 is that time domain cavitation signal is transformed into frequency domain and carries out phase offset to frequency domain cavitation signal in the embodiment of the present invention With the flow chart of array element apodization;
Fig. 2 is the time domain cavitation signal that certain ultrasonic linear-array energy converter is got and process phase offset and array element apodization processing Frequency domain cavitation signal afterwards;
Fig. 3 is the calculation flow chart of the weight vectors of adaptive beam synthesis in the embodiment of the present invention;
Fig. 4 is covariance matrix, Lagrange's multiplier iterative value, steering vector and weight vectors in adaptive beam synthesis Result;
Fig. 5 is the passive cavitation Irnaging procedures of full frequency-domain based on the synthesis of feature space adaptive beam in the embodiment of the present invention Figure;
Fig. 6 is characterized the covariance matrix of signal and noise subspace in spatially adaptive Beam synthesis, adding after projection The result of weight vector and the passive cavitation imaging of full frequency-domain;
Fig. 7 is the stream of the imaging of passive cavitation and the passive cavitation frequency multiplexed imaging of different sub- frequency domains in the embodiment of the present invention Cheng Tu;
Fig. 8 is the imaging of passive cavitation and passive cavitation frequency multiplexed imaging results of different sub- frequency domains.
Specific embodiment
The present invention is described in further detail with reference to the accompanying drawings and examples.
The present invention provides a kind of imaging of frequency domain passive cavitation and frequency multiplexed based on the synthesis of feature space adaptive beam Imaging method, comprising the following steps:
Step 1: ultrasonic imaging energy converter passively receives time domain cavitation signal, carries out Fourier's change to time domain cavitation signal It gets frequency domain cavitation signal in return, and phase offset processing is made to frequency domain cavitation signal, then utilize normalization cosine apodization function Obtain the frequency domain cavitation signal after phase offset and array element apodization processing.Specific step is as follows (Fig. 1):
(1.1) the only passive mode for receiving signal is set by supersonic imaging apparatus, is write by arbitrary waveform generator Waveform triggers focused transducer and supersonic imaging apparatus to synchronize, passive by the ultrasonic imaging energy converter of supersonic imaging apparatus The cavitation radiofrequency signal scattered at focal regions in collectiong focusing ultrasonic transducer mechanism, is known as time domain for the cavitation radiofrequency signal Cavitation signal, the time domain cavitation signal are acquired by the parallel channel data acquisition of supersonic imaging apparatus and memory module;
(1.2) assume that ultrasonic imaging energy converter (for example, ultrasonic linear-array energy converter) has N number of array element, i-th of array element is acquired The time domain cavitation signal arrived carries out Fourier transformation, obtains frequency domain cavitation signal Pi(f, x, z):
Wherein i=1,2 ..., N, t1At the beginning of being acquisition time domain cavitation signal, t2It is acquisition time domain cavitation signal Stop timing, j are imaginary unit, pi(t, x, z) is the collected time domain cavitation signal of i-th of array element, and t indicates the time;
(1.3) it calculates from imaging position (x, z) to i-th of array element (xi, 0) ultrasonic transmission time, i.e. i-th array element when Between be delayed:
Wherein, c is the acoustic propagation velocity of ultrasonic wave;
(1.4) phase offset of i-th of array element is calculated according to the resulting time delays of step (1.3):
Wherein, τiFor τiThe abbreviation of (x, z);
(1.5) to obtain phase according to frequency domain cavitation signal obtained by step (1.2) and step (1.4) resulting phase offset inclined Move treated frequency domain cavitation signal
(1.6) normalization apodizing function is calculated according to frequency domain cavitation signal obtained by step (1.2):
Wherein,It indicates for arbitrary frequency f;
(1.7) according to the position (x of imaging position (x, z) and i-th of array elementi, 0) and calculate cosine apodization function:
(1.8) returned according to cosine apodization function calculating obtained by normalization apodizing function obtained by step (1.6) and step (1.7) One changes cosine apodization function:
Apodi(f, x, z)=Apod1i(f,x,z)·Apod2i(f,x,z)
(1.9) using normalization cosine apodization function obtained by step (1.8) to the processing of step (1.5) resulting phase offset Frequency domain cavitation signal afterwards carries out array element apodization processing:
(1.10) next array element is jumped to, step (1.2)~(1.9) are repeated, until obtaining the process phase of N number of array element Frequency domain cavitation signal after offset and array element apodization processing.
Referring to fig. 2, wherein (a) is ultrasonic imaging transducer array schematic diagram, array element sum is 128, and pore size is 38mm, (b) is the 64th collected time domain cavitation signal of array element, (c) is the process phase offset and array element of the 64th array element Frequency domain cavitation signal after apodization processing.
Step 2: empty according to the frequency domain after phase offset and array element apodization processing of the resulting all array elements of step 1 Change signal to construct covariance matrix, is closed using the covariance matrix and the uncertain collection parameter building adaptive beam of steering vector At cost function, Lagrange's multiplier is introduced to the constraint condition of cost function and obtains steering vector expression formula, utilizes ox Iterative method of pausing acquires the Lagrange's multiplier in constraint condition, calculates steering vector on this basis and makees at normalization to it Reason finally obtains the weight vectors of adaptive beam synthesis.Specific step is as follows (Fig. 3):
(2.1) the frequency domain cavitation after phase offset and array element apodization processing of the resulting N number of array element of step 1 is utilized Signal constructs covariance matrix:
Wherein, S (f, x, z)=[S1(f,x,z);S2(f,x,z);...;SN(f, x, z)] be N number of array element process phase Frequency domain cavitation signal matrix after offset and array element apodization processing, []HRepresent the conjugate transposition of matrix;
(2.2) cost function of the building adaptive beam synthesis of covariance matrix obtained by step (2.1) is utilized:
Wherein, a is the steering vector to be solved,For the steering vector of hypothesis, | | | | Euclid norm is represented,For constraint condition, ε is the parameter for describing the uncertain collection of steering vector, referred to as uncertain collection parameter, []-1Generation Table matrix is inverted;
(2.3) it for cost function described in solution procedure (2.2), introduces Lagrange's multiplier and constructs Lagrange about Beam function:
Wherein, λ is Lagrange's multiplier;
(2.4) to steering vector a derivation and enable derivation is resulting to lead Lagrangian constraint function described in step (2.3) Function is zero, then obtains steering vector expression formula:
Wherein, R is step (2.1) resulting covariance matrix R (f, x, z), and hereinafter abbreviated as R, I are unit matrix;
(2.5) steering vector expression formula described in step (2.4) is rewritten according to matrix inversion lemma are as follows:
(2.6) the resulting steering vector expression formula of step (2.5) is substituted into the constraint condition of step (2.2) In, then constraint condition is rewritten are as follows:
(2.7) it calculates for convenience, Feature Space Decomposing R=U Λ U is done to covariance matrix RH, wherein U is feature vector Matrix, Λ is characterized value matrix, and enablesThen step (2.6) resulting constraint condition can convert are as follows:
Wherein, biFor i-th of element of b, γiIt is characterized i-th of diagonal element of value matrix Λ;
(2.8) Lagrange's multiplier in the constraint condition after step (2.7) conversion is solved using Newton iteration method λ will solve obtained λ and substitute into step (2.5) resulting steering vector expression formula, then steering vector can be calculated, to meter The steering vector calculated does normalized:
In Newton iteration method described in step (2.8), the condition of convergence and iteration initial value are set first, when the condition of convergence is full When sufficient, iteration stopping obtains Lagrange's multiplier.The iterative relation formula of Newton iteration method are as follows:
Wherein k=1,2 ..., λkFor the kth time iterative value of Lagrange's multiplier, λk+1For the kth+1 of Lagrange's multiplier Secondary iterative value, f (λk) be kth time iteration function, f'(λk) it is f (λk) derivative;Lagrange's multiplier iteration initial value λ1If It is set toWherein γ1For the 1st diagonal element of step (2.7) the eigenvalue matrix Λ;
(2.9) it is calculated according to the resulting normalization steering vector of step (2.8) and the resulting covariance matrix of step (2.1) The weight vectors of adaptive beam synthesis:
Referring to fig. 4, wherein (a) is empty according to the frequency domain after phase offset and array element apodization processing of 128 array elements Change the covariance matrix that signal obtains;(b) change curve that Lagrange's multiplier increases with the number of iterations, it can be seen that the 6th time Start to restrain when iteration;(c) it is normalized steering vector, is (d) weight vectors of adaptive beam synthesis.
Step 3: carrying out Feature Space Decomposing to covariance matrix obtained by step 2, obtains signal subspace, and by step The weight vectors of two resulting adaptive beam synthesis project on signal subspace, using the weight vectors after projection to step The frequency domain cavitation signal after phase offset and array element apodization processing of one resulting all array elements is weighted summation, then goes DC component is removed, the output signal of feature space adaptive beam synthesis is obtained;To the synthesis of feature space adaptive beam Output signal progress square is simultaneously overlapped on entire frequency domain, obtains the passive cavitation imaging results of full frequency-domain.Specific steps As follows (Fig. 5):
(3.1) performance of adaptive beam composition algorithm declines mainly due to caused by the disturbance of noise subspace, Middle signal subspace includes useful cavitation information, and noise subspace then includes the pseudo- shadow information for influencing image quality.For Artifact is effectively inhibited, covariance matrix R resulting to step (2.1) carries out Feature Space Decomposing:
R=U Λ UH=RS+RI
Wherein, U=[u1,u2,...,uN] it is characterized vector matrix, Λ=diag [γ12,...,γN] it is to angular moment Battle array, diagonal element are characterized value, γ1≥γ2≥...≥γN, RSFor the covariance matrix of signal subspace, RIIt is empty for noise Between covariance matrix;
The covariance matrix of step (3.1) resulting signal subspace specifically:
Wherein, US=[u1,u2,...,uL] it is the feature vector square that the corresponding feature vector of the larger characteristic value of preceding L is constituted Battle array, ΛS=diag [γ12,...,γL] be signal subspace eigenvalue matrix, diag [] indicate vector it is diagonal Change;
The covariance matrix of step (3.1) resulting noise subspace specifically:
Wherein, UI=[uL+1,uL+2,...,uN] be the feature that constitutes of the corresponding feature vector of remaining smaller characteristic value to Moment matrix, ΛI=diag [γL+1L+2,...,γN] be noise subspace eigenvalue matrix;
Parameter L is characterized value γ12,...,γNIn be greater than maximum eigenvalue (γ1) δ times all characteristic values number Mesh, δ are typically chosen in 0.2~0.5;
(3.2) it enablesThen the weight vectors of the resulting adaptive beam synthesis of step (2.9) may be expressed as:
Wherein,For the resulting normalization steering vector of step (2.8);
Since ideally, signal subspace is orthogonal to noise subspace, therefore the weighting that adaptive beam is synthesized Weight vectors of the vector project to signal subspace, after can must being projected according to step (3.5) are as follows:
(3.3) the frequency domain cavitation after phase offset and array element apodization processing of the resulting each array element of step 1 is utilized Weight vectors after signal and step (3.2) resulting projection calculate the weighted frequency domain cavitation signal of each array element:
Wherein,For the weight vectors after projection obtained by step (3.2)I-th of element, Si(f, x, z) is step 1 The frequency domain cavitation signal after phase offset and array element apodization processing of resulting i-th of array element;
(3.4) the weighted frequency domain cavitation signal of the N number of array element of ultrasonic imaging energy converter is overlapped, then can be obtained:
(3.5) DC component is got rid of from signal Q (f, x, z) obtained by step (3.4), then it is adaptive obtains feature space The output signal of Beam synthesis:
(3.6) to the output signal progress square of step (3.5) resulting feature space adaptive beam synthesis and whole It is overlapped on a frequency domain, obtains the energy of each imaging position (x, z), the i.e. passive cavitation imaging results of full frequency-domain:
Referring to Fig. 6, wherein (a) is covariance matrix of signal subspace, (b) covariance matrix of noise subspace, (c) Weight vectors for adaptive beam synthesis project to the weight vectors obtained after signal subspace, (d) passively empty for full frequency-domain It is melted into the result of picture.
Step 4: construction cavitation artifact selects optimal steering vector according to cavitation artifact than index than calculated result Uncertain collection parameter, so that it is determined that the optimal output signal of feature space adaptive beam synthesis;Son frequency is obtained on this basis The passive cavitation imaging results in domain are done standardization to the passive cavitation imaging results of different sub- frequency domains and are overlapped, obtain To passive cavitation frequency multiplexed imaging results.Specific step is as follows (Fig. 7):
(4.1) cavitation artifact of the construction based on average energy is than index:
CAR=20log10(ImeanCav/ImeanArt)
Wherein ImeanCavFor the average energy of cavitation zone, ImeanArtUnit for the average energy of artifact region, CAR is dB;
(4.2) traversal 0.01~N of range of the uncertain collection parameter ε of setting, traversal step-length generally may be configured as 0.01~1, According to Step 1: method described in two and three, obtains the passive cavitation imaging knot of full frequency-domain under different uncertain collection parameter ε Fruit;
(4.3) it is calculated under different uncertain collection parameter ε according to cavitation artifact described in step (4.1) than index CAR The CAR of the passive cavitation imaging results of full frequency-domain is imaged with this to evaluate the passive cavitation of full frequency-domain under different uncertain collection parameter ε Quality, and choose when CAR highest corresponding ε as optimal uncertain collection parameter;
The boundary of cavitation zone and artifact region is according to Energy maximum value in the passive cavitation imaging results of full frequency-domain in transverse direction It is determined with lateral coordinates and axial coordinate corresponding when axially dropping to Energy maximum value half, is cavitation area in boundary Domain is artifact region outside boundary;
(4.4) it carries out on the basis of optimal uncertain collection parameter ε Step 1: step (3.1) in step 2 and step 3 Processing described in~(3.5) obtains the optimal output signal of feature space adaptive beam synthesis
(4.5) different sub- frequency domains is selected in entire frequency domain, obtains different frequency contents, such as subharmonic (f0/2± f0/ 8), harmonic wave (nf0±f0/ 4, n=2,3 ..., 10), ultraharmonics [(2n+1) f0/2±f0/ 8, n=1,2 ..., 10] and it is wide Band noise [nf0/2+f0/ 8~(n+1) f0/2-f0/ 8, n=1,2 ..., 20] etc., wherein f0It is changed to generate the aggregation ultrasound of cavitation The tranmitting frequency of energy device;
(4.6) to the optimal output signal of the synthesis of feature space adaptive beam described in step (4.4) in step (4.5) The sub- frequency domain of difference is overlapped, then the passive cavitation imaging of different sub- frequency domains can be obtained:
Wherein, f1For the lower-frequency limit of sub- frequency domain, f2For the upper frequency limit of sub- frequency domain, FR indicates a given sub- frequency domain;
(4.7) following standardization is carried out to the passive cavitation imaging results of the resulting sub- frequency domain of difference of step (4.6):
Wherein, Indicate that, for arbitrary imaging position (x, z), M is the total number of imaging position;
(4.8) the passive cavitation imaging results of the sub- frequency domain of difference after step (4.7) resulting standardization are carried out Superposition, then can be obtained passive cavitation frequency multiplexed imaging results:
Wherein, NFR is the sub- frequency domain number for participating in frequency multiplexed imaging;
Referring to Fig. 8, wherein (a), (b), (c), (d) is according to the passive obtained differences of cavitation imaging method of traditional frequency domain The imaging results of sub- frequency domain (subharmonic, harmonic wave, ultraharmonics, broadband noise);(e), (f), (g), (h) are to be proposed according to the present invention Based on feature space adaptive beam synthesis the obtained sub- frequency domain of difference of the passive cavitation imaging method of frequency domain (subharmonic, Harmonic wave, ultraharmonics, broadband noise) imaging results;Compare (a)~(d) and (e)~(h) it is found that method proposed by the present invention can Effectively inhibit the artifact of the passive cavitation imaging of traditional frequency domain, thus improves the spatial positioning accuracy of cavitation.In addition, Fig. 8 (i) is Passive cavitation frequency multiplexed imaging results, through overfrequency (above-mentioned subharmonic, harmonic wave, ultraharmonics, four kinds of frequencies of broadband noise at Point) it is compound after, it can be seen that relative to the imaging results of each sub- frequency domain, image quality is further increased.
For Fig. 8's (i) as a result, the present invention proposes following analysis: during focusing ultrasonication, preceding cavitation scattering Multiple frequency contents between interfere with each other, and then influence subsequent cavitation behavior, and a needle is imaged in the passive cavitation of traditional frequency domain A certain sub- frequency domain is imaged, cavitation activity is cannot achieve in the effective of multiple sub- frequency domains and determines sign, while this is also to cause One reason of image quality decline.
The invention has the following advantages that
(1) collected cavitation scattered signal is carried out Beam synthesis in frequency domain by the present invention, directly can select frequency in frequency domain Rate ingredient, effectively improves computational efficiency;Beam synthesis uses the phase offset of frequency domain in the process and the time of non-temporal prolongs When, thus reduce as practical supersonic imaging apparatus sample rate is limited generate delay time error and caused by imaging artefacts;
(2) method proposed by the present invention is to carry out adaptive beam synthesis in frequency domain, solves the passive cavitation of traditional frequency domain The problem of imaging method is independent of data self character, and weight vectors are projected on signal subspace, to side Valve artifact remains cavitation information while significantly inhibition, thus realize the passive cavitation of high-resolution frequency domain at Picture;
(3) present invention has selected optimal uncertain collection parameter than this index using cavitation artifact, on this basis The high-resolution for having obtained the corresponding sub- frequency domain of the different frequencies ingredient such as subharmonic, harmonic wave, ultraharmonics and broadband noise is passively empty It is melted into picture, so that the real-time detection and quantitative analysis for stable cavitation and inertial cavitation during focusing ultrasonication have established base Plinth;
(4) present invention carries out the passive cavitation imaging of different sub- frequency domains compound, has obtained high-resolution frequency multiplexed Imaging, image quality further increase, and the frequency multiplexed imaging method proposed can be to different sub- frequency domain width and different son frequency Multiple frequency contents under the number of domain carry out comprehensive fixed sign;
(5) the passive cavitation imaging of frequency domain proposed by the present invention and frequency multiplexed imaging method can be to different focusing ultrasonic transductions Device, different ultrasonic imaging energy converters, the different cavitations generated under ultrasound emission parameter and different experiments setting that focus are imaged, It is suitable for different therapentic parts and different focused ultrasound therapy applications simultaneously, furthermore can also be used for ultrasonic cavitation transient state physics mistake The analysis and research of journey.

Claims (9)

1. it is a kind of based on feature space adaptive beam synthesis the passive cavitation imaging method of frequency domain, it is characterised in that: including with Lower step:
Step 1: passively receiving cavitation radiofrequency signal by ultrasonic imaging energy converter, carries out Fourier transformation to cavitation radiofrequency signal Frequency domain cavitation signal is obtained, utilizes normalization cosine apodization function progress apodization after making phase offset processing to frequency domain cavitation signal Processing, obtains the frequency domain cavitation signal after phase offset and array element apodization processing of all array elements of ultrasonic imaging energy converter;
Step 2: believed according to the frequency domain cavitation after phase offset and array element apodization processing of the resulting all array elements of step 1 Number construction covariance matrix, utilizes the generation of the uncertain collection parameter building adaptive beam synthesis of the covariance matrix and steering vector Valence function introduces Lagrange's multiplier by the constraint condition to the cost function and constructs Ge Lang constraint function, to glug Bright day constraint function derivation and to enable derived function be zero, obtains steering vector expression formula, steering vector expression formula is substituted into the generation It solves in the constraint condition of valence function and using Newton iteration method to obtain Lagrange's multiplier, the Lagrange obtained according to solution Multiplier calculate steering vector simultaneously steering vector is made into normalized, according to after normalized steering vector and the association side Poor matrix obtains the weight vectors of adaptive beam synthesis;
Step 3: carrying out Feature Space Decomposing to the covariance matrix, obtain signal subspace, and step 2 is resulting adaptive The weight vectors of Beam synthesis are answered to project on signal subspace, it is resulting to step 1 all using the weight vectors after projection The frequency domain cavitation signal after phase offset and array element apodization processing of array element is weighted summation, then removes direct current point Amount obtains the output signal of feature space adaptive beam synthesis;To feature space adaptive beam synthesis output signal into Row square is simultaneously overlapped on entire frequency domain, obtains the passive cavitation imaging results of full frequency-domain;
Step 4: according to cavitation artifact than selecting optimal steering vector is uncertain to collect parameter, not according to optimal steering vector Determine the optimal output signal of collection parameter determining features spatially adaptive Beam synthesis;To the optimal output signal respectively entire It is overlapped on the sub- frequency domain of difference in frequency domain, obtains the passive cavitation imaging results of different sub- frequency domains.
2. a kind of passive cavitation frequency multiplexed imaging method based on the synthesis of feature space adaptive beam, it is characterised in that: packet Include following steps:
Step 1: passively receiving cavitation radiofrequency signal by ultrasonic imaging energy converter, carries out Fourier transformation to cavitation radiofrequency signal Frequency domain cavitation signal is obtained, utilizes normalization cosine apodization function progress apodization after making phase offset processing to frequency domain cavitation signal Processing, obtains the frequency domain cavitation signal after phase offset and array element apodization processing of all array elements of ultrasonic imaging energy converter;
Step 2: believed according to the frequency domain cavitation after phase offset and array element apodization processing of the resulting all array elements of step 1 Number construction covariance matrix, utilizes the generation of the uncertain collection parameter building adaptive beam synthesis of the covariance matrix and steering vector Valence function introduces Lagrange's multiplier by the constraint condition to the cost function and constructs Ge Lang constraint function, to glug Bright day constraint function derivation and to enable derived function be zero, obtains steering vector expression formula, steering vector expression formula is substituted into the generation It solves in the constraint condition of valence function and using Newton iteration method to obtain Lagrange's multiplier, the Lagrange obtained according to solution Multiplier calculate steering vector simultaneously steering vector is made into normalized, according to after normalized steering vector and the association side Poor matrix obtains the weight vectors of adaptive beam synthesis;
Step 3: carrying out Feature Space Decomposing to the covariance matrix, obtain signal subspace, and step 2 is resulting adaptive The weight vectors of Beam synthesis are answered to project on signal subspace, it is resulting to step 1 all using the weight vectors after projection The frequency domain cavitation signal after phase offset and array element apodization processing of array element is weighted summation, then removes direct current point Amount obtains the output signal of feature space adaptive beam synthesis;To feature space adaptive beam synthesis output signal into Row square is simultaneously overlapped on entire frequency domain, obtains the passive cavitation imaging results of full frequency-domain;
Step 4: according to cavitation artifact than selecting optimal steering vector is uncertain to collect parameter, not according to optimal steering vector Determine the optimal output signal of collection parameter determining features spatially adaptive Beam synthesis;To the optimal output signal respectively entire It is overlapped on the sub- frequency domain of difference in frequency domain, obtains the passive cavitation imaging results of different sub- frequency domains;
Step 5: doing standardization to the passive cavitation imaging results of the sub- frequency domain of difference, then will be more than two of them Sub- frequency domain is overlapped by the passive cavitation imaging results of standardization, obtains passive cavitation frequency multiplexed imaging knot Fruit.
3. imaging method according to claim 1 or 2, it is characterised in that: the step 1 specifically includes the following steps:
1.1) time domain cavitation signal is passively received using ultrasonic imaging energy converter, the time domain cavitation signal refers to that focusing ultrasound changes The cavitation radiofrequency signal scattered at energy device focal regions;
1.2) Fourier transformation is carried out to the time domain cavitation signal that i-th of array element of ultrasonic imaging energy converter receives, obtains frequency domain Cavitation signal:
Wherein, i=1,2 ..., N, N are ultrasonic imaging transducer array element number, t1At the beginning of being acquisition time domain cavitation signal, t2It is the stop timing for acquiring time domain cavitation signal, j is imaginary unit, pi(t, x, z) is that the time domain that i-th of array element receives is empty Change signal, f indicates frequency;
1.3) phase offset processing is carried out to frequency domain cavitation signal obtained by step 1.2):
Wherein, pofi(f, x, z) is the phase offset of i-th of array element;
1.4) array element apodization processing is carried out to the resulting phase offset of step 1.3) treated frequency domain cavitation signal:
Wherein, Apodi(f, x, z) is the normalization cosine apodization function of i-th of array element;
1.5) step 1.2)~1.4 are repeated), until obtaining the process phase offset and battle array of N number of array element of ultrasonic imaging energy converter Frequency domain cavitation signal after first apodization processing.
4. imaging method according to claim 1 or 2, it is characterised in that: the step 2 specifically includes the following steps:
2.1) the frequency domain cavitation signal after phase offset and array element apodization processing of the resulting all array elements of step 1 is utilized Construct covariance matrix R:
Wherein, S (f, x, z)=[S1(f,x,z);S2(f,x,z);...;SN(f, x, z)] be ultrasonic imaging energy converter N number of battle array The frequency domain cavitation signal matrix after phase offset and array element apodization processing of member,It indicates for arbitrary frequency f;
2.2) cost function of the building adaptive beam synthesis of covariance matrix obtained by step 2.1) is utilized:
Wherein, a is the steering vector to be solved,For the steering vector of hypothesis, | | | | Euclid norm is represented, For constraint condition, ε is the uncertain collection parameter of steering vector;
2.3) it after step 2.2), introduces Lagrange's multiplier and constructs Lagrangian constraint function:
Wherein, λ is Lagrange's multiplier;
2.4) to steering vector a derivation and the derived function obtained by derivation is enabled to be the resulting Lagrangian constraint function of step 2.3) Zero, matrix inversion lemma is then utilized, steering vector expression formula is obtained:
Wherein, I is unit matrix;
2.5) the resulting steering vector expression formula of step 2.4) is substituted into the constraint condition of the resulting cost function of step 2.2), Then constraint condition is rewritten are as follows:
2.6) by the Feature Space Decomposing of the resulting covariance matrix R of step 2.1) to the resulting constraint condition of step 2.5) into Then row conversion is solved the lagrangian multiplier in the constraint condition after conversion using Newton iteration method, then passes through step 2.4) resulting steering vector expression formula calculates steering vector, and does normalized, obtains normalization steering vector
2.7) according to the resulting normalization steering vector of step 2.6)It is calculated with the resulting covariance matrix R of step 2.1) adaptive Answer the weight vectors w of Beam synthesis:
5. imaging method according to claim 1 or 2, it is characterised in that: the step 3 specifically includes the following steps:
3.1) the frequency domain cavitation after phase offset and array element apodization processing of all array elements obtained according to step 1 is believed Covariance matrix constructed by number carries out Feature Space Decomposing:
R=U Λ UH=RS+RI
Wherein, U=[u1,u2,...,uN] it is characterized vector matrix, Λ=diag [γ12,...,γN] it is diagonal matrix, it should Matrix diagonals element is characterized value, and γ1≥γ2≥...≥γN, RSFor the covariance matrix of signal subspace, RIFor noise The covariance matrix in space;
3.2) weight vectors that adaptive beam synthesizes are projected into signal subspace, the weight vectors after being projected
Wherein, To normalize steering vector, US=[u1,u2,...,uL] it is that preceding L larger characteristic values are corresponding Feature vector constitute signal subspace, ΛS=diag [γ12,...,γL] be signal subspace eigenvalue matrix, The diagonalization of diag [] expression vector;L is characterized the number of all characteristic values in value greater than δ times of maximum eigenvalue, and δ is 0.2~0.5;
3.3) believed using the frequency domain cavitation after phase offset and array element apodization processing of each array element of ultrasonic imaging energy converter Number and the resulting projection of step 3.2) after weight vectors calculate the weighted frequency domain cavitation signal of each array element:
Wherein,For the weight vectors after the resulting projection of step 3.2)I-th of element, Si(f, x, z) changes for ultrasonic imaging The frequency domain cavitation signal after phase offset and array element apodization processing of energy i-th of array element of device, wherein i=1,2 ..., N, N For ultrasonic imaging transducer array element number;
3.4) the weighted frequency domain cavitation signal of the N number of array element of ultrasonic imaging energy converter is overlapped, obtains signal Q (f, x, z):
3.5) DC component is got rid of from signal Q (f, x, z) obtained by step 3.4), then obtains the conjunction of feature space adaptive beam At output signalIt is rightProgress square is simultaneously overlapped on entire frequency domain, is obtained each at image position Set the energy of (x, z):
Wherein,It indicates for arbitrary frequency f.
6. imaging method according to claim 1 or 2, it is characterised in that: the step 4 specifically includes the following steps:
4.1) cavitation artifact of the construction based on average energy is than index CAR:
CAR=20log10(ImeanCav/ImeanArt)
Wherein, ImeanCavFor cavitation zone or the average energy of cavitation zone selected part, ImeanArtFor artifact region or pseudo- shadow zone The average energy of domain selected part;
4.2) according to the cavitation artifact ratio or cavitation zone and artifact region difference selected part of cavitation zone and artifact region The mean value of cavitation artifact ratio evaluates the passive cavitation image quality of full frequency-domain under different ε, and ε is the uncertain collection parameter of steering vector, And it chooses the corresponding ε when CAR or CAR mean value highest and is led as the uncertain collection parameter of optimal steering vector according to optimal The optimal output signal that feature space adaptive beam synthesizes is obtained to the uncertain collection parameter of vectorWherein, ε Traversal range is 0.01~N, and traversal step-length is 0.01~1;
4.3) different sub- frequency domains is selected, to the optimal output signal of step 4.2) resulting feature space adaptive beam synthesis It is overlapped respectively in different sub- frequency domains, then obtains the passive cavitation imaging of different sub- frequency domains:
Wherein, FR indicates given a certain sub- frequency domain, f1For the lower-frequency limit of the sub- frequency domain, f2For the upper frequency limit of the sub- frequency domain.
7. imaging method according to claim 2, it is characterised in that: the step 5 specifically includes the following steps:
5.1) the passive cavitation imaging results of the sub- frequency domain of difference resulting to step 4 are standardized, and are then folded Add, obtain passive cavitation frequency multiplexed imaging results:
Wherein, NFR is the sub- frequency domain number for participating in frequency multiplexed imaging,For the process for participating in frequency multiplexed imaging The passive cavitation imaging results of the sub- frequency domain of i-th of standardization.
8. a kind of passive cavitation imaging system of frequency domain based on the synthesis of feature space adaptive beam, it is characterised in that: including phase The passive cavitation imaging of position offset and array element apodization processing module, adaptive beam synthesis weight vectors computing module, full frequency-domain The passive cavitation image-forming module of module and sub- frequency domain;The phase offset and array element apodization processing module are used for ultrasonic imaging Passively received cavitation radiofrequency signal is fourier transformed and is converted to frequency domain cavitation signal energy converter, and to frequency domain cavitation signal Make to carry out apodization processing using normalization cosine apodization function after phase offset processing, so that it is all to obtain ultrasonic imaging energy converter The frequency domain cavitation signal after phase offset and array element apodization processing of array element;The adaptive beam synthesizes weight vectors meter It calculates the frequency domain cavitation signal that module is used for according to all array elements after phase offset and array element apodization and constructs covariance square Battle array, using the uncertain collection parameter building adaptive beam synthesis of the covariance matrix and steering vector cost function, by pair The constraint condition of the cost function introduces Lagrange's multiplier construction Ge Lang constraint function, will be by constraining Lagrange Function derivation and to enable derived function be that zero resulting steering vector expression formula is substituted into the constraint condition of the cost function and utilized Newton iteration method solves Lagrange's multiplier, calculates steering vector and by steering vector according to solving obtained Lagrange's multiplier Make normalized, and according to through normalized steering vector and the covariance matrix obtain adaptive beam synthesis Weight vectors;The weight vectors that the passive cavitation image-forming module of the full frequency-domain is used to synthesize the adaptive beam project To institute on using the resulting signal subspace of Feature Space Decomposing of the covariance matrix, using the weight vectors after projection The frequency domain cavitation signal after phase offset and array element apodization processing for stating all array elements is weighted summation, removal direct current point It is overlapped on entire frequency domain after amount, and square processing, to obtain the passive cavitation imaging results of full frequency-domain;The son The passive cavitation image-forming module of frequency domain is used for according to cavitation artifact than selecting optimal steering vector is uncertain to collect parameter, Yi Jigen According to the optimal output signal of the uncertain collection parameter determining features spatially adaptive Beam synthesis of optimal steering vector, and to this Optimal output signal is overlapped on the sub- frequency domains of difference in entire frequency domain respectively, to obtain the passive sky of different sub- frequency domains Change imaging results.
9. a kind of passive cavitation frequency multiplexed imaging system based on the synthesis of feature space adaptive beam, it is characterised in that: packet It includes phase offset and array element apodization processing module, adaptive beam synthesizes the passive cavitation of weight vectors computing module, full frequency-domain The passive cavitation image-forming module and passive cavitation frequency multiplexed image-forming module of image-forming module, sub- frequency domain;The phase offset and Array element apodization processing module is used for that passively received cavitation radiofrequency signal to be fourier transformed and is converted to ultrasonic imaging energy converter Frequency domain cavitation signal, and normalization cosine apodization function progress apodization is utilized after making phase offset processing to frequency domain cavitation signal Processing, to obtain the frequency domain cavitation letter after phase offset and array element apodization processing of all array elements of ultrasonic imaging energy converter Number;The adaptive beam synthesis weight vectors computing module is used to be become according to all array elements by phase offset and array element Frequency domain cavitation signal after mark is constructed covariance matrix, is constructed certainly using the covariance matrix and the uncertain collection parameter of steering vector It adapts to the cost function of Beam synthesis, introduce Lagrange's multiplier construction Ge Lang by the constraint condition to the cost function Constraint function, will be by Lagrangian constraint function derivation and to enable derived function be that zero resulting steering vector expression formula substitutes into institute The Lagrange for stating in the constraint condition of cost function and solving Lagrange's multiplier using Newton iteration method, being obtained according to solution Multiplier calculates steering vector and steering vector is made normalized, and according to steering vector through normalized and described Covariance matrix obtains the weight vectors of adaptive beam synthesis;The passive cavitation image-forming module of the full frequency-domain is used for will be described The weight vectors of adaptive beam synthesis project to empty using the resulting signal subspace of Feature Space Decomposing of the covariance matrix Between it is upper, empty using frequency domain by phase offset and array element apodization processing after of the weight vectors after projection to all array elements Change after signal is weighted summation, removal DC component, and square processing and be overlapped on entire frequency domain, to obtain complete The passive cavitation imaging results of frequency domain;The passive cavitation image-forming module of the sub- frequency domain is used for more optimal than selecting according to cavitation artifact The uncertain collection parameter of steering vector, and according to the uncertain collection parameter determining features spatially adaptive wave of optimal steering vector The optimal output signal of Shu Hecheng, and to being folded in the optimal the output signal respectively sub- frequency domains of difference in entire frequency domain Add, to obtain the passive cavitation imaging results of different sub- frequency domains;The passive cavitation frequency multiplexed image-forming module is used for institute The passive cavitation imaging results for stating different sub- frequency domains do standardization, and by the process standard of more than two of them sub- frequency domain The passive cavitation imaging results for changing processing are overlapped, to obtain passive cavitation frequency multiplexed imaging results.
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