CN109171675A - A kind of wearable device and the hemodynamic parameter measurement method based on the equipment - Google Patents
A kind of wearable device and the hemodynamic parameter measurement method based on the equipment Download PDFInfo
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- 230000000004 hemodynamic effect Effects 0.000 title claims abstract description 66
- 238000000691 measurement method Methods 0.000 title claims abstract description 24
- 238000002847 impedance measurement Methods 0.000 claims abstract description 27
- 238000005259 measurement Methods 0.000 claims abstract description 27
- 238000013507 mapping Methods 0.000 claims abstract description 18
- 230000005284 excitation Effects 0.000 claims abstract description 7
- 238000004891 communication Methods 0.000 claims description 18
- 230000001133 acceleration Effects 0.000 claims description 12
- 238000003062 neural network model Methods 0.000 claims description 10
- 230000000747 cardiac effect Effects 0.000 claims description 9
- 230000017531 blood circulation Effects 0.000 claims description 8
- 230000002861 ventricular Effects 0.000 claims description 8
- 210000000577 adipose tissue Anatomy 0.000 claims description 6
- 230000003862 health status Effects 0.000 claims description 6
- 239000008280 blood Substances 0.000 claims description 4
- 210000004369 blood Anatomy 0.000 claims description 4
- 230000005611 electricity Effects 0.000 claims description 4
- 230000036541 health Effects 0.000 claims description 4
- 238000013528 artificial neural network Methods 0.000 claims 1
- 210000004218 nerve net Anatomy 0.000 claims 1
- 238000000034 method Methods 0.000 description 10
- 230000001435 haemodynamic effect Effects 0.000 description 8
- 230000008569 process Effects 0.000 description 8
- 238000010586 diagram Methods 0.000 description 6
- 208000012788 shakes Diseases 0.000 description 6
- 210000001367 artery Anatomy 0.000 description 5
- 230000036996 cardiovascular health Effects 0.000 description 5
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- 238000000605 extraction Methods 0.000 description 3
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- 238000012937 correction Methods 0.000 description 1
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- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 230000002526 effect on cardiovascular system Effects 0.000 description 1
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/02—Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/0002—Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network
- A61B5/0004—Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network characterised by the type of physiological signal transmitted
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/02—Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
- A61B5/02028—Determining haemodynamic parameters not otherwise provided for, e.g. cardiac contractility or left ventricular ejection fraction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/05—Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves
- A61B5/053—Measuring electrical impedance or conductance of a portion of the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
- A61B5/6801—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be attached to or worn on the body surface
- A61B5/6802—Sensor mounted on worn items
- A61B5/681—Wristwatch-type devices
Abstract
The present invention provides a kind of wearable device and the hemodynamic parameter measurement method based on the equipment, the wearable device includes ontology, the microprocessor for being additionally provided with impedance measurement device on ontology and being electrically connected with impedance measurement device, impedance measurement device includes a pair of electrodes and the second pair of electrode set on the body, each includes an excitation electrode and a measuring electrode to electrode；And the microprocessor being electrically connected with impedance measurement device, microprocessor are used to according to the human body impedance pulse wave for each obtaining electrode measurement, obtain the hemodynamic parameter of human body；To accurately measure the impedance pulse wave of human body by setting a pair of electrodes on the body and second pair of electrode, and then the pulse Impedance characteristics of user are extracted from human body impedance pulse wave by microprocessor, according to pulse Impedance characteristics and default mapping relations, the hemodynamic parameter of user is obtained；Realize the diversity and accuracy of measurement data.
Description
Technical field
The invention belongs to a kind of intelligence wearing technical field more particularly to wearable device and based on the blood flow of the equipment
Mechanics parameter measurement method.
Background technique
It moves and the facilitation of health is widely accepted, and as wearable device is risen, filled using various electronics
It is set to oneself plan and statistics movement, and assesses movement effects, including the variation such as weight, heart rate, body ingredient, is used to form one
The feedback of closed loop improves movement effects；But movement is also far not limited to several points as above to the facilitation of human body；For example,
Long-term motion can bring the improvement of cardiac pumping ability, to show as the improvement of human bloodstream kinetically, including often fight defeated
Output, cardiac output etc..
Hemodynamic parameter measurement at present is still confined to hospital and clinical application, and there has been no preferable wearable sides
Formula can be convenient in the hemodynamic parameter information for measuring human body；For example, existing wrist-watch carries out blood flow using PPG mode
The pressure by outside capillary, tightness degree, the colour of skin of sensor and skin etc. are tended to when kinetic measurement to be influenced
The consistency and repeatability of measurement are difficult to ensure；And for wearable device, longitudinal comparison of continuous measurement result is sometimes compared
Absolute accuracy on some breakpoint is even more important, because user is concerned with variation tendency, rather than absolute numerical value, therefore
The pursuit emphasis for performance of wearable haemodynamics device will be different with the related device for being used for hospital and clinic
, former concerns are consistency that is easy to use, being convenient for continuous measurement and measurement result and repeatability in order to which longitudinal direction is right
Than, and the latter pays close attention to absolute accuracy.
Therefore, the measurement of wearable hemodynamic parameter must can effectively eliminate above-mentioned shadow using a kind of mode
It rings, just can guarantee the repeatability and consistency of measurement.The measurement of hemodynamic parameter is influenced by the other parameters of body, as can
It carries out effectively combining the accuracy for being then conducive to improve index of correlation measurement.
Summary of the invention
The purpose of the present invention is to provide a kind of wearable device and the hemodynamic parameter measurement side based on the equipment
Method, it is intended to the hemodynamic parameter for being difficult to continue by wearable device accurately to obtain human body due to the prior art is solved,
Lead to the problem of the hemodynamic parameter inaccuracy of wearable device measurement human body.
On the one hand, the present invention provides a kind of wearable devices, including ontology；
Impedance measurement device is additionally provided on the ontology, the impedance measurement device includes first set on the body
To electrode and second pair of electrode, it is each it is described include an excitation electrode and a measuring electrode to electrode；
And the microprocessor being electrically connected with the impedance measurement device, the microprocessor are set on the body；
The microprocessor is used for the impedance pulse wave according to each human body obtained to electrode measurement, from institute
The pulse Impedance characteristics for extracting the user in human body impedance pulse wave are stated, are reflected according to the pulse Impedance characteristics with default
Relationship is penetrated, the hemodynamic parameter of the user is obtained.
Preferably, the pulse Impedance characteristics include: the wave amplitude of human body impedance pulse wave, human body impedance pulse wave it is micro-
Divide the differential forward direction maximum value of negative sense maximum value, human body impedance pulse wave, human body impedance pulse wave differential map is most
The time span of the vertex absolute value of maximum forward wave of the predetermined point to impedance pulse wave differential map on the left of big negative wave vertex.
It is further preferred that the pulse Impedance characteristics further include: waveform area of often fighting, impedance pulse wave cycle.
It is further preferred that predetermined point is maximum on the left of the maximum negative wave vertex of the human body impedance pulse wave differential map
15% amplitude point of negative wave.
Preferably, a pair of electrodes of the impedance measurement device and second pair of electrode are arranged at the back of the ontology
Face, with contact the position of human body it is corresponding.
Preferably, the wearable device, further includes:
The acceleration transducer being electrically connected with the microprocessor, the acceleration transducer is for measuring the human body
Data are shaken, the acceleration transducer is set on the body.
Preferably, the wearable device, further includes:
The wireless communication module being electrically connected with the microprocessor, the wireless communication module are used for the resistance of the human body
Module is uploaded to remote server and/or end by wireless communication for the Wave data of anti-pulse wave and/or the stroke output
End equipment；
The microprocessor can also by the wireless communication module and the remote server and/or terminal device into
Row communication, default and more new data, preset data include weight, age, gender, the height information of the human body.
Preferably, microprocessor described in the wearable device is also used to be determined according to the hemodynamic parameter and wear
The human body health status；
The wearable device further includes the display being electrically connected with the microprocessor, and the display is mounted on described
The front of ontology, the Wave data for showing the human body impedance pulse wave, the stroke output and/or the human body
Health status.
On the other hand, the present invention also provides a kind of hemodynamic parameter measurement method based on above-mentioned wearable device,
It is characterised by comprising:
The impedance pulse wave for the human body worn simultaneously using described a pair of electrodes and second pair of electrode measurement；
The pulse Impedance characteristics that the user is extracted from the human body impedance pulse wave, according to the pulse wave impedance
Feature and default mapping relations, obtain the hemodynamic parameter of the user.
Preferably, the pulse Impedance characteristics include: the wave amplitude of human body impedance pulse wave, human body impedance pulse wave it is micro-
Divide the differential forward direction maximum value of negative sense maximum value, human body impedance pulse wave, human body impedance pulse wave differential map is most
The time span of the vertex absolute value of maximum forward wave of the predetermined point to impedance pulse wave differential map on the left of big negative wave vertex.
It is further preferred that the pulse Impedance characteristics further include: waveform area of often fighting, impedance pulse wave cycle.
It is further preferred that extracting the step of the pulse Impedance characteristics of the user from the human body impedance pulse wave
Suddenly, comprising:
Period, the wave amplitude, waveform area of often fighting of the human body impedance pulse wave are extracted from the human body impedance pulse wave
Parameter.
It is further preferred that predetermined point is maximum on the left of the maximum negative wave vertex of the human body impedance pulse wave differential map
15% amplitude point of negative wave.
It is further preferred that obtaining the blood flow of the user according to the pulse Impedance characteristics and default mapping relations
The step of kinetic parameter, comprising:
Using the human body impedance pulse wave and user's height, stroke output is calculated according to default mapping relations.
Preferably, from the pulse Impedance characteristics for extracting the user in the human body impedance pulse wave before the step of,
Further include:
Corresponding distortion impedance pulse wave when user shake is removed from the human body impedance pulse wave measured,
To obtain removing the human body impedance pulse wave after the distortion impedance pulse wave.
Preferably, according to the pulse Impedance characteristics and default mapping relations, the haemodynamics of the user is obtained
The step of parameter, comprising:
According to formulaObtain the stroke output, wherein SV is indicated
The stroke output, ρ are blood conductivity, and value is 130~150 Ω cm, L is equivalent length and user's height at just
Than Z0For basic impedance, (dZ/dt)nmaxIndicate maximum negative wave in the corresponding impedance differential map of impedance pulse wave of the human body
Vertex absolute value, LVET indicates left ventricular ejection time, and the LVET takes the maximum negative sense of human body impedance pulse wave differential map
On the left of wave crest point 15% amplitude point to human body impedance pulse wave differential map maximum forward wave vertex absolute value time span.
It is further preferred that obtaining the blood flow of the user according to the pulse Impedance characteristics and default mapping relations
The step of kinetic parameter, comprising:
By height H, the basal impedance Z in the pulse Impedance characteristics0, the corresponding impedance of the human body impedance pulse wave
The vertex absolute value (dZ/dt) of maximum negative wave in differentialnmax, left ventricular ejection time LVET, human body impedance pulse wave wave amplitude,
Waveform area, periodical input to preset neural network model obtain often fighting for the user by the neural network model
Output quantity.
It is further preferred that the parameter for being input to preset neural network model further include the weight of the user, the age,
Gender.
It is further preferred that the hemodynamic parameter measurement method further include:
Human body component parameter, the people are calculated according to the height of the user, weight, age, gender and human body impedance
Body composition parameter includes at least body fat rate.
It is further preferred that after the step of obtaining the stroke output of the user by the neural network model,
Further include:
Using one of weight, age, gender, body fat rate parameter or a variety of, and in conjunction with the pulse Impedance characteristics
Stroke output described in parameters revision.
It is further preferred that obtaining the blood flow of the user according to the pulse Impedance characteristics and default mapping relations
The step of kinetic parameter, further includes:
The weight, height and heart rate for obtaining the user calculate every according to the weight, height and the stroke output
It fights output index, cardiac output and heart output index.
The present invention can realize that the non-invasive of hemodynamic parameter is measured by wearable device, including ontology, on ontology
The microprocessor for being additionally provided with impedance measurement device and connecting with impedance measurement device, impedance measurement device include being located at ontology
On a pair of electrodes and second pair of electrode, each include an excitation electrode and a measuring electrode to electrode；To logical
It crosses setting a pair of electrodes on the body and second pair of electrode accurately measures the impedance pulse wave of human body, and then pass through micro- place
Manage hemodynamic parameter including stroke output that device obtains human body；Realize measurement data diversity and performance it is same
Step is promoted.
Detailed description of the invention
Fig. 1 is the structural schematic diagram for the wearable device that the embodiment of the present invention one provides；
Fig. 2 is the topology example figure for the wearable device that the embodiment of the present invention one provides；
Fig. 3 and Fig. 4 respectively illustrates wearable device front and the preferred structure at the back side of the offer of the embodiment of the present invention one
Schematic diagram；
Fig. 5 is the circuit structure signal of wearable device provided by Embodiment 2 of the present invention；
Fig. 6 is the implementation flow chart for the hemodynamic parameter measurement method that the embodiment of the present invention three provides；
Fig. 7 is the waveform diagram of the human body impedance pulse wave for the haemodynamics measurement method that the embodiment of the present invention three provides；
Fig. 8 is the corresponding human body impedance pulse wave of human body impedance pulse wave shown in Fig. 7 of the offer of the embodiment of the present invention three
Differential map；
Fig. 9 is the preferred implementation flow chart for the hemodynamic parameter measurement method that the embodiment of the present invention four provides.
Specific embodiment
In order to make the objectives, technical solutions, and advantages of the present invention clearer, with reference to the accompanying drawings and embodiments, right
The present invention is further elaborated.It should be appreciated that the specific embodiments described herein are merely illustrative of the present invention, and
It is not used in the restriction present invention.
Specific implementation of the invention is described in detail below in conjunction with specific embodiment:
Embodiment one:
Fig. 1 show the embodiment of the present invention one offer wearable device structure, for ease of description, illustrate only with
The relevant part of the embodiment of the present invention.
Wearable device 100 provided in an embodiment of the present invention is described with bracelet, which wears 100 at wrist,
Including ontology 101, the impedance measurement device being arranged on ontology 101 102 and the micro- place being connect with impedance measurement device 102
Manage device 103.
Ontology 101 includes impedance measurement device 102, and a pair of electrodes of impedance measurement device 102 and second pair of electrode are equal
It is arranged on ontology 101, for measuring the human-body biological electrical impedance letter worn in the wearable device 100 between user's both hands
Breath obtains the human body impedance pulse wave of user in wearable device to pass through the human-body biological electrical impedance information of user, this
Sample dresses particular device without user, accurate, the automatic acquisition to the human body impedance pulse wave of user can be realized.
Preferably, in embodiments of the present invention, a pair of electrodes and second pair of electrode be arranged at ontology 101 the back side,
It is corresponding with position at the wrist of contact human body, it, will not be to user while facilitating the human-body biological electrical impedance information for obtaining user
Bring the restriction on more limbs.
Microprocessor 103 is used for the human body impedance pulse obtained according to measuring electrode in impedance measurement device 102 to measurement
Wave extracts the pulse Impedance characteristics of user from human body impedance pulse wave, is closed according to pulse Impedance characteristics and default mapping
System, obtains the hemodynamic parameter of user, and hemodynamic parameter includes stroke output, further, haemodynamics
Parameter can also include often fight output index, cardiac output, heart output index etc., thus the haemodynamics of Overall Acquisition user
Parameter, convenient for understanding the health status of the cardiovascular aspect of user.Preferably, pulse Impedance characteristics include human body impedance pulse wave
Wave amplitude, the differential negative sense maximum value of human body impedance pulse wave, human body impedance pulse wave differential forward direction maximum value,
Maximum forward wave of the predetermined point to impedance pulse wave differential map on the left of the maximum negative wave vertex of human body impedance pulse wave differential map
Vertex absolute value time span, to improve the acquisition accuracy of hemodynamic parameter.It is further preferred that pulse wave
Impedance characteristic further includes often fight waveform area, impedance pulse wave cycle, the maximum negative sense wave crest of human body impedance pulse wave differential map
Point left side predetermined point is 15% amplitude point of maximum negative wave, so that the acquisition for further increasing hemodynamic parameter is accurate
Degree.
Preferably, microprocessor 103 passes through the measurement electricity of a pair of electrodes when obtaining the hemodynamic parameter of human body
Extremely to and second pair of electrode measuring electrode to measurement wearable device on user human body impedance pulse wave, from human body impedance arteries and veins
It fights and extracts the pulse Impedance characteristics of user in wave waveform, according to pulse Impedance characteristics and default mapping relations, obtain user
Hemodynamic parameter, without dress particular device, can be realized to the accurate, automatic of user's human body impedance pulse wave
It obtains, and then obtains the hemodynamic parameter of user.Wherein, microprocessor 103 is arranged on ontology 101.
As shown in Figure 2, it is preferable that wearable device 100 further includes the acceleration transducer connecting with microprocessor 103
104, acceleration transducer 104 is installed on the body, with the shake data for measuring human body.
Preferably, wearable device 100 further includes the wireless communication module 105 connecting with microprocessor 103, wireless communication
Module 105 is mounted on ontology 101, the human body impedance arteries and veins for obtaining microprocessor 103 under the control of microprocessor 103
Mode is uploaded to remote server and/or mobile terminal to waveform data and/or the stroke output of fighting by wireless communication.Its
In, remote server can be the big data platform or server of management user health, with the painstaking effort for continuing to monitor user
Pipe health status, mobile terminal then can be used for terminal for user in wearable device 100, such user can pass through it is mobile eventually
End easily understands the cardiovascular health state of oneself.It is further preferred that mobile terminal is the prison of user in wearable device
People or lineal relative's user terminal are protected, so that guardian or lineal relative can understand user in wearable device whenever and wherever possible
Cardiovascular health state, when in wearable device user occur corresponding disease when, guardian or lineal relative can have found in time
And remind, improve the intelligence degree of wearable device.
Preferably, microprocessor 103 is also used to determine the health of user in wearable device according to hemodynamic parameter
State, to directly obtain the health status of user by wearable device, user can be by wearable device (for example, wearable
The voice-output unit etc. of equipment) intuitively know itself cardiovascular health state.It is further preferred that wearable device 100
It further include the display 106 being connect with microprocessor 103, display 106 is mounted on ontology 101, in this way, in microprocessor
User in 103 acquisition human body impedance pulse waveform data, hemodynamic parameter, stroke output and/or wearable device
Cardiovascular health state after, can directly be shown by display 106, user is facilitated timely, intuitively to understand angiocarpy
State.
As illustratively, Fig. 3 and Fig. 4 respectively illustrate the schematic structure at wearable device front and the back side.As schemed
Show, wearable device includes ontology 10, microprocessor 2, wearable device further include display 3, impedance measurement device first
To electrode 4 with second pair of electrode 5, display 3 is located at the front of ontology 10, and a pair of electrodes 4 and second pair of electrode 5 are equipped with more
A excitation electrode and measuring electrode and the back side for being respectively positioned on ontology 10, wireless communication module 9 are mounted on ontology 10, for
Human body impedance pulse waveform data and/or stroke output that microprocessor 2 obtains are passed through into nothing under the control of microprocessor 2
Line communication mode is uploaded to remote server and/or mobile terminal.
Wearable device provided in an embodiment of the present invention, including ontology are additionally provided with impedance measurement device, Yi Jiyu on ontology
The microprocessor of impedance measurement device connection, impedance measurement device includes a pair of electrodes and the second pair of electricity set on the body
Pole each includes an excitation electrode and a measuring electrode to electrode；To first pair of electricity by setting on the body
Pole and second pair of electrode accurately measure the impedance pulse wave of human body, and then the haemodynamics of human body is obtained by microprocessor
Parameter including stroke output；Realize the diversity of measurement data and the Synchronous lifting of performance.
Embodiment two:
Fig. 5 shows the electrical block diagram of wearable device provided by Embodiment 2 of the present invention, for ease of description,
Only parts related to embodiments of the present invention are shown, and wherein the inside of ontology 10, which is equipped with, carries out operation to the physiological parameter of human body
The microcontroller 91 of processing, microcontroller 91 are electrically connected with the acceleration transducer 8 for reading human motion state, microcontroller 91
Electrical connection is there are also the impedance measurement device 93 for measuring human body impedance, and there are also display human body physiological parameter letters for the electrical connection of microcontroller 91
The display 3 of breath；
Preferably, device further includes wireless communication module 92, and wireless communication module 92 is electrically connected with microcontroller 91, wirelessly
The human body physiological parameter information that 91 calculation process of microcontroller obtains is uploaded to Cloud Server or terminal device by communication module 92,
It is convenient to control.
Further, it can also be communicated with Cloud Server or terminal device by wireless communications chips 92；
Further, impedance measurement device 93 includes a pair of electrodes 4 and second pair of electrode 5, a pair of electrodes 4 and second pair
Electrode 5 is equipped with multiple excitation electrodes and measuring electrode；So that measurement is more acurrate.
Embodiment three:
Fig. 6 shows the implementation process of the hemodynamic parameter measurement method of the offer of the embodiment of the present invention three, in order to just
In explanation, only parts related to embodiments of the present invention are shown, and details are as follows:
In step s 201, wearable device is worn on the limbs of human body through a pair of electrodes and second pair of electrode
Measure the impedance pulse wave of human body.
In step S202, the wave character of impedance pulse wave is extracted from the waveform of the impedance pulse wave of human body, according to
The wave character of impedance pulse wave and default mapping relations, the hemodynamic parameter for obtaining human body.
The embodiment of the present invention is suitable for intelligent wearable equipment, can get by the wearable device and wears this and wearable set
The hemodynamic parameter of standby human body.
Better pulse Impedance characteristics in order to obtain, in embodiments of the present invention, it is preferable that from human body impedance pulse wave
Before the middle impedance pulse wave characteristic for extracting user, removes and use from the human body impedance pulse waveform that step S201 measurement obtains
Family corresponding distortion impedance pulse wave when shaking, to obtain the human body impedance pulse wave after removal distortion impedance pulse wave, thus
Stablized, the true human body impedance pulse wave of human body, improves the accuracy of hemodynamic parameter.It is further preferred that
When removing user's shake from human body impedance pulse wave when corresponding distortion pulse wave, human body is detected by acceleration transducer and is trembled
Wobble variation period corresponding pulse wave is rejected, to obtain accurate human body impedance pulse wave, and then is avoided by dynamic variation
The pulse Impedance characteristics of mistake extract, and guarantee the accuracy of hemodynamic parameter.
When human body carries out biological impedance using wearable device, slightly trembling for body may be inevitably present
It is dynamic, to cause the variation of the contact condition of human skin and measuring electrode, to influence human body impedance measuring value, and then influence
The waveform of impedance pulse wave causes impedance pulse wave feature extraction difficulty or mistake therefore to detect people by acceleration transducer
The movement (shake) of body, the corresponding Impedance Wave of run duration section is filtered out, and then avoids the feature extraction of mistake, guarantees blood flow
Mechanics parameter calculates correct.
Fig. 7 schematically shows human body impedance pulse wave, is as shown in the figure two complete pulse (heartbeat) periods,
The middle period is T0, first Wave crest and wave trough of diagram of impedance pulse wave is Zamp to wave amplitude0, the diagram second week of impedance pulse wave
The area of phase waveform is Zarea0, it is integral of the impedance pulse wave to baseline BaseLine (line of two neighboring trough)；Z00
It is basal impedance.It is defined in periodic waveform although the wave amplitude of impedance pulse wave, period, area etc. are all based in the figure,
But generally take in actual use the analog value of several periodic waveforms do average treatment come using.
It is further preferred that pulse Impedance characteristics further include often fight waveform area and impedance pulse wave cycle, in this way,
When extracting the pulse Impedance characteristics of user from human body impedance pulse wave, human body impedance arteries and veins is extracted from human body impedance pulse wave
It fights period of wave, wave amplitude, waveform area parameter of often fighting.
When obtaining the stroke output in hemodynamic parameter, using human body impedance pulse wave and user's height, press
Stroke output is calculated according to default mapping relations, to improve the accuracy of stroke output acquisition.
When obtaining the hemodynamic parameter of user, it is preferable that according to formula 1:
The stroke output in hemodynamic parameter is obtained, to simplify blood flow while guaranteeing the accuracy of stroke output
The acquisition process of kinetic parameter, SV indicates stroke output in the formula, and ρ is blood conductivity, and value is 130~150
Ω cm, L are equivalent length, directly proportional to user's height, Z0For basic impedance, (dZ/dt)nmaxIndicate human body impedance pulse wave
The vertex absolute value of maximum negative wave in corresponding derivative of impedance, LVET indicate that left ventricular ejection time, LVET take human body impedance
Maximum forward wave of 15% amplitude point to human body impedance pulse wave differential map on the left of the maximum negative wave vertex of pulse wave differential map
Vertex absolute value time span.
It is another preferably, obtain user hemodynamic parameter when, by height H, the base in pulse Impedance characteristics
Plinth impedance Z0, in the corresponding derivative of impedance of human body impedance pulse wave maximum negative wave vertex absolute value (dZ/dt)nmax, left ventricle
Ejection time LVET, human body impedance pulse wave wave amplitude, waveform area, periodical input pass through mind to preset neural network model
The stroke output that user is obtained through network model, to improve the acquisition accuracy of stroke output.
After the stroke output for obtaining user, one in weight, age, gender, body fat rate parameter can also be utilized
Kind is a variety of, and combines pulse Impedance characteristics parameters revision stroke output, to further increase obtaining for stroke output
Take accuracy.
Preferably, pulse Impedance characteristics include that the wave amplitude of human body impedance pulse wave, the differential of human body impedance pulse wave are negative
To maximum value, the differential forward direction maximum value of human body impedance pulse wave, the maximum of human body impedance pulse wave differential map is negative
To wave crest point left side predetermined point to the time span of the vertex absolute value of the maximum forward wave of impedance pulse wave differential map.
As illustratively, human body impedance pulse wave differential map as shown in Figure 8, wherein C0Point is the vertex of negative wave,
Amplitude takes absolute value as dZamp_C0, i.e. dZamp_C0=(dZ/dt)nmax；B0Point is C0The preset in point left side, can represent ventricle
The starting point for penetrating blood, generally takes dZamp_B0=15%*dZamp_C0Corresponding point is used as B0Point；X0Point is the vertex of forward wave, can
Represent the end of ventricular ejection, therefore B0Point arrives X0The time interval LVET of point0Ventricular ejection time can be represented.But due to
The difference of measuring point, LVET0It is not precisely equal to ventricular ejection time, but can be used as one of a ventricular ejection time
Positive correlation amount.In addition, L is an amount relevant with height in SV formula, in embodiments of the present invention, between the both hands of measurement
Impedance pulse wave (impedance rheogram), therefore more precisely L is amount relevant with double upper limb length+shoulder breadths, but because upper
Limb length and height have proportionate relationship, it can thus be assumed that be it is related to height H, be denoted as L0；The relationship L of itself and height0=F (H)
It can be obtained by the experiment of limited times, generally take L0=H*0.9*0.5；Z00For basic impedance, human body impedance value between two hands is taken
A quarter.
Further, output index of often fighting, the heart that can be obtained in hemodynamic parameter according to the stroke output of acquisition are defeated
Output and heart output index.When obtaining these parameters, it is preferable that weight, the height for obtaining user, according to the weight of acquisition,
Height and stroke output calculate often fight output index, cardiac output and heart output index, thus quick based on stroke output
Haemodynamics other parameters are obtained, while being further simplified hemodynamic parameter acquisition process, comprehensively obtains and uses
The hemodynamic parameter at family improves user's cardiovascular health state and fixes exactness really.When obtaining these parameters, often fight
Output index S I=SV/BSA, cardiac output CO=HR*SV, heart output index CI=CO/BSA.Wherein BSA indicates body
Surface area, BSA=0.0061* height (cm)+0.0128* weight (kg) -0.1529, HR indicate arteries and veins (heart) rate, HR=60/T0, T0
Indicate pulse (heartbeat) period.
Example IV:
Fig. 9 shows the implementation process of the hemodynamic parameter measurement method of the offer of the embodiment of the present invention four, in order to just
In explanation, only parts related to embodiments of the present invention are shown, and details are as follows:
Preferably, which can be wearable with further increasing in wearable device
The precision of the hemodynamic parameter of device measuring human body.
In step s 701, while the shake data and people of acceleration transducer and impedance measurement device measurement human body being utilized
The impedance pulse wave of body；
In step S702, human body impedance pulse wave is handled, removes the waveform in human body shake stage, retains and stablizes
Waveform；
In step S703, the processing such as baseline drift are filtered to human body impedance pulse wave and obtain being suitble to feature extraction
Processing after human body impedance pulse wave (as shown in Figure 7), and to human body impedance pulse wave carry out differential process, with obtain human body resistance
Anti- pulse wave differential map (as depicted in figure 8)；
In step S704, human body impedance pulse is obtained from human body impedance pulse wave and human body impedance pulse wave differential map
Wave characteristic.
In embodiments of the present invention, human body impedance pulse wave characteristic include dZamp_C0, LVET0, Z00, T0, Zamp0,
Zarea0, T0 and the average value for taking 8 pulse wave cycles.Wherein, dZamp_C0=8.7 Ω/s, LVET0=0.201s, Z00=
150 Ω, Zamp0=0.6 Ω, Zarea0=0.26 Ω s, T0=0.86s；
In step S705, by H=170 centimetres of the step S704 parameter obtained and the height prestored, it is sent to micro- place
Device is managed, stroke output basic value SV0 is calculated according to formula 1 or preparatory trained neural network model, when use formula 1
When, SV=61.4mL/beat can be calculated.
In step S706, microprocessor is sent by weight and the age prestored, gender information, calculating is often fought defeated
Output correction amount k0, SV1, stroke output SV=k0*SV0+SV1；
In embodiments of the present invention, according to neural network model, then step S705 and step S706 may be incorporated in one
In a neural network model, and then k0=1, SV1=0 when use formula 1.
In step S707, microprocessor, arteries and veins (heart) rate HR=60/T0, by micro- are sent by weight, height, heart rate
Processor calculates often fight output index SI=SV/BSA, cardiac output CO=HR*SV, heart output index CI=CO/BSA.
In embodiments of the present invention, BSA is body surface area, BSA (m2)=0.0061* height (cm)+0.0128* weight
(kg)-0.1529。
Further, human body component can also be calculated according to the height of user, weight, age, gender and human body impedance
Parameter, wherein human body component parameter includes at least body fat rate, to obtain the same of hemodynamic parameter by wearable device
When, human body component parameter is obtained, the acquisition process of human body component parameter is simplified, improves the intelligent journey of wearable device
Degree.
In embodiments of the present invention, by obtaining weight, height and the heart rate of user, and then according to the weight of acquisition, body
Height, heart rate and stroke output obtain often fight output index, cardiac output and heart output index by wearable device, thus base
In stroke output quick obtaining haemodynamics other parameters, it is being further simplified the same of hemodynamic parameter acquisition process
When, it can comprehensively obtain the hemodynamic parameter of user.
The foregoing is merely illustrative of the preferred embodiments of the present invention, is not intended to limit the invention, all in essence of the invention
Made any modifications, equivalent replacements, and improvements etc., should all be included in the protection scope of the present invention within mind and principle.
Claims (21)
1. a kind of wearable device, which is characterized in that including ontology；
Impedance measurement device is additionally provided on the ontology, the impedance measurement device includes the first pair of electricity set on the body
Pole and second pair of electrode, it is each it is described include an excitation electrode and a measuring electrode to electrode；
And the microprocessor being electrically connected with the impedance measurement device, the microprocessor are set on the body；
The microprocessor is used for the impedance pulse wave according to each human body obtained to electrode measurement, from the people
The pulse Impedance characteristics that the user is extracted in body impedance pulse wave are closed according to the pulse Impedance characteristics and default mapping
System, obtains the hemodynamic parameter of the user.
2. wearable device as described in claim 1, which is characterized in that the pulse Impedance characteristics include: human body impedance
The wave amplitude of pulse wave, the differential negative sense maximum value of human body impedance pulse wave, the differential of human body impedance pulse wave are positive maximum
Absolute value, maximum of the predetermined point to impedance pulse wave differential map on the left of the maximum negative wave vertex of human body impedance pulse wave differential map
The time span of the vertex absolute value of forward wave.
3. wearable device as claimed in claim 2, which is characterized in that the pulse Impedance characteristics further include: wave of often fighting
Shape area, impedance pulse wave cycle.
4. wearable device as claimed in claim 2, which is characterized in that the maximum of the human body impedance pulse wave differential map is negative
Predetermined point is 15% amplitude point of maximum negative wave on the left of to wave crest point.
5. wearable device as described in claim 1, which is characterized in that a pair of electrodes of the impedance measurement device and
Two pairs of electrodes be arranged at the ontology the back side, with contact the position of human body it is corresponding.
6. wearable device as described in claim 1, which is characterized in that further include:
The acceleration transducer being electrically connected with the microprocessor, the acceleration transducer are used to measure the shake of the human body
Data, the acceleration transducer are set on the body.
7. wearable device as described in claim 1, which is characterized in that further include be electrically connected with the microprocessor it is wireless
Communication module, the wireless communication module be used for by the Wave data of the impedance pulse wave of the human body and/or it is described often fight it is defeated
Module is uploaded to remote server and/or terminal device to output by wireless communication；
The microprocessor can also be led to by the wireless communication module and the remote server and/or terminal device
Letter, default and more new data, preset data include weight, age, gender, the height information of the human body.
8. wearable device as described in claim 1, which is characterized in that the microprocessor is also used to according to the blood flow
Mechanics parameter determines the health status for the human body worn；
The wearable device further includes the display being electrically connected with the microprocessor, and the display is mounted on the ontology
Front, the Wave data for showing the human body impedance pulse wave, the stroke output and/or the human body health
State.
9. a kind of hemodynamic parameter measurement method based on wearable device described in claim 1, which is characterized in that packet
It includes:
The impedance pulse wave for the human body worn simultaneously using described a pair of electrodes and second pair of electrode measurement；
The pulse Impedance characteristics that the user is extracted from the human body impedance pulse wave, according to the pulse Impedance characteristics
With default mapping relations, the hemodynamic parameter of the user is obtained.
10. hemodynamic parameter measurement method as claimed in claim 9, which is characterized in that the pulse Impedance characteristics
It include: differential negative sense maximum value, the human body impedance pulse wave of the wave amplitude of human body impedance pulse wave, human body impedance pulse wave
Differential forward direction maximum value, predetermined point is to impedance pulse wave on the left of the maximum negative wave vertex of human body impedance pulse wave differential map
The time span of the vertex absolute value of the maximum forward wave of differential map.
11. hemodynamic parameter measurement method as claimed in claim 10, which is characterized in that the pulse Impedance characteristics
Further include: waveform area of often fighting, impedance pulse wave cycle.
12. hemodynamic parameter measurement method as claimed in claim 11, which is characterized in that from the human body impedance pulse
The step of pulse Impedance characteristics of the user are extracted in wave, comprising:
Period, the wave amplitude, waveform area parameter of often fighting of the human body impedance pulse wave are extracted from the human body impedance pulse wave.
13. hemodynamic parameter measurement method as claimed in claim 11, which is characterized in that the human body impedance pulse wave
Predetermined point is 15% amplitude point of maximum negative wave on the left of the maximum negative wave vertex of differential map.
14. hemodynamic parameter measurement method as claimed in claim 11, which is characterized in that according to the pulse wave impedance
Feature and default mapping relations, the step of obtaining the hemodynamic parameter of the user, comprising:
Using the human body impedance pulse wave and user's height, stroke output is calculated according to default mapping relations.
15. hemodynamic parameter measurement method as claimed in claim 11, which is characterized in that from the human body impedance pulse
Before the step of extracting the pulse Impedance characteristics of the user in wave, further includes:
Corresponding distortion impedance pulse wave when user shake is removed from the human body impedance pulse wave measured, with
Human body impedance pulse wave to after the removal distortion impedance pulse wave.
16. hemodynamic parameter measurement method as claimed in claim 11, which is characterized in that according to the pulse wave impedance
Feature and default mapping relations, the step of obtaining the hemodynamic parameter of the user, comprising:
According to formulaObtain the stroke output, wherein described in SV expression
Stroke output, ρ are blood conductivity, and value is 130~150 Ω cm, L is equivalent length, directly proportional to user's height,
Z0For basic impedance, (dZ/dt)nmaxIndicate maximum negative wave in the corresponding impedance differential map of impedance pulse wave of the human body
Vertex absolute value, LVET indicate that left ventricular ejection time, the LVET take the maximum negative wave of human body impedance pulse wave differential map
On the left of vertex 15% amplitude point to human body impedance pulse wave differential map maximum forward wave vertex absolute value time span.
17. hemodynamic parameter measurement method as claimed in claim 11, which is characterized in that according to the pulse wave impedance
Feature and default mapping relations, the step of obtaining the hemodynamic parameter of the user, comprising:
By height H, the basal impedance Z in the pulse Impedance characteristics0, the corresponding derivative of impedance of the human body impedance pulse wave
The vertex absolute value (dZ/dt) of middle maximum negative wavenmax, left ventricular ejection time LVET, human body impedance pulse wave wave amplitude, waveform
Area, periodical input to preset neural network model obtain the output of often fighting of the user by the neural network model
Amount.
18. hemodynamic parameter measurement method as claimed in claim 17, which is characterized in that be input to preset nerve net
The parameter of network model further includes weight, age, the gender of the user.
19. hemodynamic parameter measurement method as claimed in claim 17, which is characterized in that further include:
Calculate human body component parameter according to the height of the user, weight, age, gender and human body impedance, the human body at
Parameter is divided to include at least body fat rate.
20. hemodynamic parameter measurement method as claimed in claim 19, which is characterized in that pass through the neural network mould
Type obtained after the step of stroke output of the user, further includes:
Using one of weight, age, gender, body fat rate parameter or a variety of, and in conjunction with the pulse Impedance characteristics parameter
Correct the stroke output.
21. hemodynamic parameter measurement method as claimed in claim 11, which is characterized in that according to the pulse wave impedance
Feature and default mapping relations, the step of obtaining the hemodynamic parameter of the user, further includes:
The weight, height and heart rate for obtaining the user are often fought defeated according to the calculating of the weight, height and the stroke output
Index, cardiac output and heart output index out.
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| PCT/CN2019/105793 WO2020057448A1 (en) | 2018-09-20 | 2019-09-12 | Hemodynamics parameter measurement apparatus and measurement method |
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