CN109134288A - A kind of device and method of synthesizing betaine - Google Patents
A kind of device and method of synthesizing betaine Download PDFInfo
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- CN109134288A CN109134288A CN201810992134.4A CN201810992134A CN109134288A CN 109134288 A CN109134288 A CN 109134288A CN 201810992134 A CN201810992134 A CN 201810992134A CN 109134288 A CN109134288 A CN 109134288A
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- persimmon
- monoxone
- reaction
- trimethylamine
- reaction tube
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C227/14—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof
- C07C227/18—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof by reactions involving amino or carboxyl groups, e.g. hydrolysis of esters or amides, by formation of halides, salts or esters
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- C—CHEMISTRY; METALLURGY
- C01—INORGANIC CHEMISTRY
- C01F—COMPOUNDS OF THE METALS BERYLLIUM, MAGNESIUM, ALUMINIUM, CALCIUM, STRONTIUM, BARIUM, RADIUM, THORIUM, OR OF THE RARE-EARTH METALS
- C01F17/00—Compounds of rare earth metals
- C01F17/20—Compounds containing only rare earth metals as the metal element
- C01F17/253—Halides
- C01F17/271—Chlorides
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C227/38—Separation; Purification; Stabilisation; Use of additives
Abstract
The invention discloses a kind of device and methods of synthesizing betaine, it is related to the preparation method of additive product, apparatus of the present invention are by reaction tube, quaternary ammoniated kettle, amination liquid circulating pump, alkali solution of beet storage tank is successively connected to pipeline, the feed pipe of monoxone persimmon and trimethylamine is respectively arranged on reaction tube, quaternary ammoniated liquid circulating pump accesses reaction kettle after connecting condenser by circulating line, PH meter is installed on circulating line, continuous detection is carried out by PH meter to control the doses of disengaging system, material reacts in reaction kettle and reaction tube, forced circulation is carried out by circulating pump to be cooled down, the reaction heat of removal system；Utilization rate of equipment and installations of the invention is high, and byproduct chlorination persimmon is widely used, can be used as feed addictive, can also be in fields such as medicine, military project, fireworks as raw material, and added value of product is high；The by-product for solving hydroxyacetic acid in production process simultaneously is formed, and the yield and purity of product synthesis process are improved.
Description
Technical field
The invention belongs to the fields such as medicine, cosmetics, food, feed, plant growth regulator, are related to additive product
Preparation method, in particular to a kind of device and method of synthesizing betaine.
Background technique
Glycine betaine is the trimethyl derivative of glycine, different universally present in a kind of intracorporal alkaloid of animals and plants
Degree it is present in nearly all animal and plant body.It is widely used in medicine, cosmetics, food, feed, plant growth regulator
Equal fields.There is moisture-keeping function in terms of cosmetics；Medical aspect has liver protection function, and U.S. FDA ratifies sweet tea in terms of food
Dish alkali is as safety food additive and diet nutritional hardening agent (GRAS number 4223)；Glycine betaine can be improved energy in food
Utilization rate, improve the effective absorption and utilization rate of amino acid, while having protective effect to liver；It is answered in livestock and poultry and aquatic livestock
With more extensive, dietary digestibility of energy can be improved using horizontal, stablize vitamin quality in feed, have protection to make liposoluble vitamin
With, be adjusted osmotic pressure, glycine betaine facilitate maintain cell water and ionic equilibrium, animal generate stress when, maintain enteron aisle
Integrality and intestinal health effect are significant, reduce aquatic livestock in fishing, transportational process death, reduce feed cost.
The glycine betaine that the production technology of glycine betaine mainly uses soda ash, monoxone, trimethylamine to be synthesized for raw material at present,
Monoxone and soda ash first react in water phase first, generate sodium chloroacetate, and then trimethylamine is added in the aqueous solution of sodium chloroacetate, instead
It should be the aqueous solution of glycine betaine and sodium chloride, process flow chart is as shown in Figure 1.The technique exists following insufficient: 1) synthesis process
The byproduct sodium chloride of middle generation, various chemical reactions all generate byproduct sodium chloride at present, and added value is low, comprehensively utilize difficulty
Greatly, the wasting of resources；2) in synthesis process, because monoxone hydrolyzes to form hydroxyacetic acid in alkaline condition generation, sodium carbonate is being added
PH is excessively high in topical solutions in the process, by-product hydroxyacetic acid easy to form, to the impurities affect of final products；3) prior art
Middle synthesizing betaine uses intermittent reaction, and product yield is low, conversion ratio 98.5% or so.
Summary of the invention
The present invention aiming at the problems existing in the prior art, discloses a kind of device and method of synthesizing betaine,
Using continuous production processes, and devises and the device of the continuous production processes is suitble to carry out synthesizing betaine, it is of the invention
Device uses continuous feed, and can adjust control, while chlorination with the input and output material that PH meter carries out reaction process with continuous discharge
Persimmon is the catalyst of Isosorbide-5-Nitrae addition reaction, and bootable react carries out to product direction, reaction product purity is high.Solves existing skill
The problem of art.
The present invention is implemented as follows:
The device of synthesizing betaine disclosed by the invention includes: to be connected with reaction tube, quaternary ammoniated kettle, amination liquid in turn by pipeline
Circulating pump, alkali solution of beet storage tank, material react in reaction kettle and reaction tube, since reaction tube is circulating line, in chloroethene
When pipeline is added simultaneously in sour persimmon and trimethylamine, reaction is had begun, and the Fluid pressure in pipeline can promote reaction to accelerate speed；Institute
The quaternary ammoniated liquid circulating pump stated by circulating line connect condenser after access quaternary ammoniated kettle, by circulating pump carry out forced circulation into
Row cooling, removes the reaction heat of system, obtains reliable conversion ratio；The reaction tube front end also passes through feed pipe parallel connection and connects
It is connected to trimethylamine measuring tank and monoxone persimmon neutralization chamber, flow is equipped between the trimethylamine measuring tank and reaction tube
Meter is equipped with monoxone persimmon and pumps between the monoxone persimmon neutralization chamber and reaction tube；The quaternary ammoniated circulating line is pumping
It is counted on the pipeline of import equipped with PH, continuous detection is carried out by PH meter to control the doses of disengaging system；The beet alkali soluble
Enrichment facility is arranged in liquid storage tank rear end；The water that the enrichment facility generates enters monoxone persimmon neutralization chamber.
The invention also discloses the methods of the synthesizing betaine using above-mentioned apparatus, the method is as follows:
Step 1: monoxone, water are placed in monoxone persimmon neutralization chamber first, water is 1.6 times of quality of chloroacetic acid, then to chlorine
It is slowly added to carbonic acid persimmon in acetic acid persimmon neutralization chamber, time control is added at 2.5-3.0 hours, control molar ratio is (1.01-
1.02): 0.167 monoxone and carbonic acid persimmon generates monoxone persimmon in aqueous phase reactions, and temperature is controlled at 25-40 DEG C, when PH reaches
Reaction terminates when 7.0-7.5 is required；Monoxone persimmon is to carry out neutralization reaction by carbonic acid persimmon, with monoxone to form monoxone persimmon, temperature
At 25-40 DEG C, monoxone persimmon solution purity is high for degree control, and by-product is few.Secondly, energy consumption reduces in production process, chlorination persimmon
There are 7 hydrates, separation process steam consumption reduces, and cost-saved because reducing reduced vapor, the technique three wastes are reduced.
Step 2: the monoxone persimmon being prepared will be reacted in step 1 and is pumped into reaction tube by monoxone persimmon, together
When the trimethylamine in trimethylamine measuring tank is added into reaction tube；Wherein molar ratio be 1.0:(0.33-0.34) monoxone
Persimmon carries out quaternary amine with trimethylamine and is combined to, and synthesis reaction temperature control is at 40-60 DEG C, and PH control is 8.6-9.5, and generated time is
2.5-3 hour；Monoxone persimmon reacts in quaternary ammoniated kettle and reaction tube with trimethylamine；Since reaction tube is circulating line, in chlorine
When pipeline is added simultaneously in acetic acid persimmon and trimethylamine, reaction is had begun, and the Fluid pressure in pipeline can promote reaction to accelerate speed.
Step 3: forced circulation is carried out by quaternary ammoniated liquid circulating pump and is cooled down, material passes through condensation in cyclic process
Device, material walk tube side, and cooling water walks shell side, are exchanged by heat and remove reaction heat.
Step 4: during the reaction, when the material PH in kettle reaches 8.6-9.5, pass through the outlet conduit of circulating pump
Completely reacted material is conveyed to alkali solution of beet storage tank, when the quaternary ammoniated solution in alkali solution of beet storage tank reaches greater than 10 cubes
When, alkali solution of beet is subjected to negative pressure concentration in concentration kettle, be concentrated to beet alkali content be 55-57% when, concentration terminates, dense
Chlorination persimmon is centrifuged out in solution after contracting, and the distilled water of concentration process separation carries out being back to use monoxone persimmon neutralization chamber,
Chlorination persimmon is sold as byproduct.Water reuse after treatment after alkali solution of beet concentration, reduces the wave of freshwater resources
Take.
Further, the optimal reaction temperature that the monoxone persimmon and trimethylamine carry out quaternary ammonium reaction is controlled in 50-53
℃。
Further, the chlorination persimmon chlorination persimmon is both the by-product of synthesizing betaine, while urging as synthesis process
Agent.Byproduct chlorination persimmon is widely used, and added value is high, reduces the energy consumption of beet alkali production process.
The beneficial effect of the present invention compared with prior art is:
The present invention uses continuous production processes, and monoxone persimmon of the invention is to carry out neutralization reaction shape by carbonic acid persimmon, with monoxone
At monoxone persimmon, monoxone persimmon solution purity is high, and hydroxyacetic acid by-product is few；Reaction is completed the solution after concentration and is carried out
It is centrifugated out chlorination persimmon, the distilled water of concentration process separation carries out being back to use neutralized system, and chlorination persimmon is carried out as byproduct
Sale；The byproduct for producing glycine betaine process becomes the high chlorination persimmon of added value, improves the product profit and competitiveness of enterprise,
Product can be improved 1000 yuan/ton of profit；Belong to green circulatory reaction；
The present invention uses continuous feed and continuous discharge, adjusts control, while chlorination with the input and output material that PH meter carries out reaction process
Persimmon is the catalyst of Isosorbide-5-Nitrae addition reaction, and bootable react carries out to product direction, reaction product purity is high；
Raw materials technology utilization rate of the invention improves, and impurity is reduced, and the hydroxyacetic acid of synthesis process reduces 0.3%, and conversion ratio is reachable
To 99.5%, product purity improves 1%, and cost-saved 100 yuan/ton of product；Solves original process byproduct sodium chloride simultaneously
It is difficult to handle problem, byproduct chlorination persimmon application range is more extensive；Energy consumption reduces in production process, and chlorination persimmon has 7 hydrates,
Separation process steam consumption reduces, cost-saved because reducing reduced vapor, and the technique three wastes are reduced；
The present invention realizes continuous production, utilization rate of equipment and installations using monoxone persimmon, trimethylamine as the method for Material synthesis glycine betaine
Height, utilization rate of equipment and installations improve 20%；And byproduct chlorination persimmon is widely used, can be used as feed addictive, it can also be in medicine, army
As raw material, added value of product is high in the fields such as work, fireworks；The by-product for solving hydroxyacetic acid in production process simultaneously is formed,
Improve the yield and purity of product synthesis process.
Detailed description of the invention
The process flow chart for the glycine betaine that the prior art synthesizes in Fig. 1 background of invention；
The process flow chart for the glycine betaine that Fig. 2 present invention synthesizes.
Specific embodiment
It is clear to keep the purpose of the present invention, technical solution and effect clearer, example is exemplified below to the present invention into one
Step is described in detail.It should be understood that specific implementation described herein is not intended to limit the present invention only to explain the present invention.
The device of glycine betaine synthesized in the present invention first successively include reaction tube, quaternary ammoniated kettle, amination liquid circulating pump,
Alkali solution of beet storage tank, quaternary ammoniated liquid circulating pump (solution circulation pump) access quaternary ammoniated kettle after connecting condenser by circulating line.
Reaction tube front end also passes through feed pipe and is connected separately with trimethylamine measuring tank and monoxone persimmon neutralization chamber, trimethylamine measuring tank
And flowmeter is equipped between reaction tube, it is equipped with monoxone persimmon between monoxone persimmon neutralization chamber and reaction tube and pumps；Quaternary ammoniated liquid
Circulating pump accesses quaternary ammoniated kettle after connecting condenser by circulating line, and quaternary ammoniated circulating line is equipped with PH on the pipeline of pump inlet
Meter.Enrichment facility is arranged in alkali solution of beet storage tank rear end；The water that enrichment facility generates enters monoxone persimmon neutralization chamber.
As shown in Fig. 2, Fig. 2 is the process flow chart for the glycine betaine that the present invention synthesizes, specific technique are as follows:
Step 1: monoxone, water are placed in monoxone persimmon neutralization chamber first, water is 1.6 times of quality of chloroacetic acid, then to chlorine
It is slowly added to carbonic acid persimmon in acetic acid persimmon neutralization chamber, time control is added at 2.5-3 hours, control molar ratio is (1.01-1.02):
0.167 monoxone and carbonic acid persimmon generates monoxone persimmon in aqueous phase reactions, and PH control is 7.0-7.5, and temperature is controlled in 25-40
℃；
Step 2: the monoxone persimmon being prepared will be reacted in step 1 and is pumped into reaction tube by monoxone persimmon, simultaneously will
Trimethylamine in trimethylamine measuring tank is added into reaction tube；Wherein molar ratio be 1.0:(0.33-0.34) monoxone persimmon with
Trimethylamine carries out quaternary amine and is combined to, and at 40-60 DEG C, monoxone persimmon and trimethylamine carry out quaternary ammonium reaction for synthesis reaction temperature control
Optimal reaction temperature control at 50-53 DEG C, PH control is 8.6-9.5, and generated time is 2.5-3 hours；
Step 3: forced circulation is carried out by quaternary ammoniated liquid circulating pump and is cooled down；
Step 4: during the reaction, when the material PH in kettle reaches 8.6-9.5, by the outlet conduit of circulating pump to sweet tea
Dish aqueous slkali storage tank conveys completely reacted material, when the quaternary ammoniated solution in alkali solution of beet storage tank reaches greater than 10 cubic inches,
Alkali solution of beet is subjected to negative pressure concentration in concentration kettle, be concentrated to beet alkali content be 55-57% when, concentration terminates, after concentration
Solution be centrifuged out chlorination persimmon, the distilled water of concentration process separation carries out being back to use monoxone persimmon neutralization chamber, chlorination
Persimmon is sold as byproduct.
The present invention use continuous production processes, by reaction tube, quaternary ammoniated kettle, solution circulation pump, alkali solution of beet storage tank according to
It is secondary to be connected to pipeline, the feed pipe of monoxone persimmon and trimethylamine is respectively arranged on reaction tube, quaternary ammoniated liquid circulating pump is by following
Reaction tube is accessed after endless tube road connection pipe bundle condenser, PH meter is installed on above-mentioned circulating line, is continuously examined by PH meter
It surveys to control the doses of disengaging system, material reacts in reaction kettle and reaction tube, carries out forced circulation progress by circulating pump
It is cooling, the reaction heat of system is removed, reliable conversion ratio is obtained.
Specific embodiment is as follows:
Embodiment 1
First in monoxone persimmon neutralization chamber put into solid monoxone, then plus data water, be then slowly added into carbonic acid persimmon.Water is
1.6 times of quality of chloroacetic acid, the monoxone and carbonic acid persimmon that control molar ratio is 1.01:0.167 generate monoxone in aqueous phase reactions
Persimmon, reaction end PH control are 7.0, and at 25 DEG C, reaction time control is 3 hours for temperature control.Monoxone is used after reaction
Monoxone persimmon control flow is transported to the reaction tube of quaternary ammonium reaction system by persimmon pump, while being in molar ratio the chlorine of 1.0:0.33
The amount of acetic acid persimmon, which is passed through trimethylamine and carries out quaternary amine, to be combined to, and at 40 DEG C, PH control is 8.6 for synthesis reaction temperature control, when synthesis
Between control be 2.5 hours, completely reacted material pump is transported in alkali solution of beet slot, reaches PH by control input and output material flow
It is required for 8.6.When the quaternary ammoniated solution in alkali solution of beet storage tank reaches greater than 10 cubic inches, by alkali solution of beet pump conveying
To enrichment process, aqueous solutions of betaine is concentrated to beet alkali content in concentration kettle when being 55-57%, and concentration terminates, after concentration
Chlorination persimmon is centrifuged out in solution, and the distilled water of concentration process separation carries out being back to use monoxone persimmon neutralization chamber, chlorination persimmon
It is sold as byproduct.
Embodiment 2
The specific steps and embodiment 1 of the present embodiment are consistent, the difference is that the present embodiment uses molar ratio for 1.015:
0.167 monoxone and carbonic acid persimmon generates monoxone persimmon in aqueous phase reactions, and PH control is 7.1, and temperature is controlled at 30 DEG C;Molar ratio
It is combined to for the monoxone persimmon and trimethylamine progress quaternary amine of 1.0:0.335, synthesis reaction temperature control is in 51 DEG C, PH control
9.5, generated time is 3 hours.
Embodiment 3
The specific steps and embodiment 1 of the present embodiment are consistent, the difference is that the present embodiment 3 uses molar ratio for 1.02:
0.167 monoxone and carbonic acid persimmon generates monoxone persimmon in aqueous phase reactions, and PH control is 7.2, and temperature is controlled at 35 DEG C;Molar ratio
It is combined to for the monoxone persimmon and trimethylamine progress quaternary amine of 1.0:0.34, synthesis reaction temperature control is in 51 DEG C, PH control
9.0, generated time is 2.8 hours.
Embodiment 4
The specific steps and embodiment 1 of the present embodiment are consistent, the difference is that the present embodiment 3 uses molar ratio for 1.02:
0.167 monoxone and carbonic acid persimmon generates monoxone persimmon in aqueous phase reactions, and PH control is 7.3, and temperature is controlled at 40 DEG C;Molar ratio
It is combined to for the monoxone persimmon and trimethylamine progress quaternary amine of 1.0:0.34, synthesis reaction temperature control is in 55 DEG C, PH control
9.3, generated time is 3 hours.
Embodiment 5
The specific steps and embodiment 1 of the present embodiment are consistent, the difference is that the present embodiment 3 uses molar ratio for 1.02:
0.167 monoxone and carbonic acid persimmon generates monoxone persimmon in aqueous phase reactions, and PH control is 7.5, and temperature is controlled at 40 DEG C;Molar ratio
It is combined to for the monoxone persimmon and trimethylamine progress quaternary amine of 1.0:0.34, synthesis reaction temperature control is in 60 DEG C, PH control
9.5, generated time is 3 hours.
Monoxone persimmon is generated in aqueous phase reactions according to monoxone in above embodiments 1 ~ 4 and carbonic acid persimmon.As a comparison, this hair
The bright glycine betaine synthesized using soda ash in the prior art, monoxone, trimethylamine for raw material, other conditions are implemented with more than
1 ~ 4 reaction process of example and state modulator are consistent.Comparison monoxone hydrolyzes to form hydroxyacetic acid in alkaline condition generation and contains
Utilize monoxone and carbonic acid persimmon in the variation of the hydroxyacetic acid of aqueous phase reactions generation monoxone persimmon generation in amount and the present invention.Chlorine
Acetic acid hydrolyzes to form hydroxyacetic acid in alkaline condition generation, and PH is excessively high in topical solutions during the addition process for sodium carbonate, is easy shape
At by-product hydroxyacetic acid, when temperature control is 25 DEG C -40 DEG C in synthesis, with soda ash N-process by-product hydroxyacetic acid
Content compares the embodiment of the present invention 1 ~ 4 in 0.4-0.5%, and temperature control is 25 DEG C -40 DEG C in synthesis, with carbonic acid persimmon in
Content with byproduct in process object hydroxyacetic acid is respectively 0.1-0.18%, and the hydroxyacetic acid of synthesis process of the present invention is reduced
0.3%, conversion ratio can reach 99.5%, and product purity improves 1%.Since purity of the by-product hydroxyacetic acid to final products has shadow
It rings, therefore, monoxone persimmon of the present invention is to carry out neutralization reaction by carbonic acid persimmon, with monoxone to form monoxone persimmon, and monoxone persimmon is molten
Liquid purity is high, by-product is few, and chlorination persimmon is sold as byproduct, while chlorination persimmon is the catalyst of Isosorbide-5-Nitrae addition reaction,
Bootable react carries out to product direction, reaction product purity is high.
The above is only a preferred embodiment of the present invention, it is noted that for the ordinary skill people of the art
For member, without departing from the principle of the present invention, several improvement can also be made, these improvement also should be regarded as of the invention
Protection scope.
Claims (4)
1. a kind of device of synthesizing betaine, which is characterized in that the device is connected with reaction tube, quaternary amine in turn by pipeline
Change kettle, amination liquid circulating pump, alkali solution of beet storage tank；The quaternary ammoniated liquid circulating pump is followed by by circulating line connection condenser
Enter quaternary ammoniated kettle；The reaction tube front end also passes through feed pipe and is connected in parallel in trimethylamine measuring tank and monoxone persimmon
And slot, flowmeter, the monoxone persimmon neutralization chamber and reaction are equipped between the trimethylamine measuring tank and reaction tube
Monoxone persimmon is equipped between pipe to pump；The quaternary ammoniated circulating line is counted on the pipeline of pump inlet equipped with PH；The beet
Enrichment facility is arranged in aqueous slkali storage tank rear end；The water that the enrichment facility generates enters monoxone persimmon neutralization chamber.
2. a kind of method of the synthesizing betaine using claim 1 described device, which is characterized in that method is as follows:
Step 1: monoxone, water are placed in monoxone persimmon neutralization chamber first, water is 1.6 times of quality of chloroacetic acid, then to chlorine
It is slowly added to carbonic acid persimmon in acetic acid persimmon neutralization chamber, time control is added at 2.5-3 hours, control molar ratio is (1.01-1.02):
0.167 monoxone and carbonic acid persimmon generates monoxone persimmon in aqueous phase reactions, and temperature is controlled at 25-40 DEG C, when PH reaches 7.0-7.5
It is required that when reaction terminate；
Step 2: the monoxone persimmon being prepared will be reacted in step 1 and is pumped into reaction tube by monoxone persimmon, simultaneously will
Trimethylamine in trimethylamine measuring tank is added into reaction tube；Wherein molar ratio be 1.0:(0.33-0.34) monoxone persimmon with
Trimethylamine carries out quaternary amine and is combined to, and at 40-60 DEG C, PH control is 8.6-9.5, generated time 2.5- for synthesis reaction temperature control
3 hours；Material reacts in quaternary ammoniated kettle and reaction tube；Reaction tube is circulating line, is added simultaneously in monoxone persimmon and trimethylamine
When entering pipeline, reaction is had begun；
Step 3: forced circulation is carried out by quaternary ammoniated liquid circulating pump and is cooled down, material passes through condenser, object in cyclic process
Material walks tube side, and cooling water walks shell side, is exchanged by heat and removes reaction heat；
Step 4: during the reaction, when the material PH in kettle, which reaches 8.6-9.5 technique, to be required, pass through the outlet of circulating pump
Pipeline conveys completely reacted material to alkali solution of beet storage tank, when the quaternary ammoniated solution in alkali solution of beet storage tank reaches greater than 10
Alkali solution of beet is carried out negative pressure concentration by cubic inch in concentration kettle, be concentrated to beet alkali content be 55-57% when, concentration knot
Chlorination persimmon is centrifuged out in beam, the solution after concentration, and the distilled water of concentration process separation be back to use in monoxone persimmon
And slot, chlorination persimmon is as byproduct.
3. the method for synthesizing betaine according to claim 2, which is characterized in that the monoxone persimmon and trimethylamine into
The optimal reaction temperature of row quaternary ammonium reaction is controlled at 50-53 DEG C.
4. the method for synthesizing betaine according to claim 2, which is characterized in that the chlorination persimmon chlorination persimmon is both to close
At the by-product of glycine betaine, while the catalyst as synthesis process.
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Cited By (2)
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| CN110235998A (en) * | 2019-06-21 | 2019-09-17 | 宜兴市天石饲料有限公司 | A kind of preparation method for the compound betaine mixing Cortex Eucommiae element bionic acid agent |
| CN110981747A (en) * | 2019-12-27 | 2020-04-10 | 赞宇科技集团股份有限公司 | Production process and device of high-quality betaine surfactant |
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| CN106938975A (en) * | 2017-01-20 | 2017-07-11 | 农安旺泉饲料科技有限公司 | A kind of method for preparing glycine betaine and beet alkali hydrochlorate |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN110235998A (en) * | 2019-06-21 | 2019-09-17 | 宜兴市天石饲料有限公司 | A kind of preparation method for the compound betaine mixing Cortex Eucommiae element bionic acid agent |
| CN110981747A (en) * | 2019-12-27 | 2020-04-10 | 赞宇科技集团股份有限公司 | Production process and device of high-quality betaine surfactant |
| CN110981747B (en) * | 2019-12-27 | 2024-02-20 | 赞宇科技集团股份有限公司 | Production process and device of high-quality betaine surfactant |
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Application publication date: 20190104 |