CN109132219B - Stem cell injection transportation keeps device - Google Patents
Stem cell injection transportation keeps device Download PDFInfo
- Publication number
- CN109132219B CN109132219B CN201810807519.9A CN201810807519A CN109132219B CN 109132219 B CN109132219 B CN 109132219B CN 201810807519 A CN201810807519 A CN 201810807519A CN 109132219 B CN109132219 B CN 109132219B
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- Prior art keywords
- cabinet body
- transportation
- transportation cabinet
- pipe
- stem cell
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- 238000002347 injection Methods 0.000 title claims abstract description 48
- 239000007924 injection Substances 0.000 title claims abstract description 48
- 210000000130 stem cell Anatomy 0.000 title claims abstract description 45
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 claims abstract description 201
- 229910052757 nitrogen Inorganic materials 0.000 claims abstract description 99
- 238000004321 preservation Methods 0.000 claims abstract description 40
- 239000007788 liquid Substances 0.000 claims abstract description 39
- 238000005507 spraying Methods 0.000 claims abstract description 28
- 239000007789 gas Substances 0.000 claims abstract description 20
- 238000013519 translation Methods 0.000 claims abstract description 17
- 230000000712 assembly Effects 0.000 claims abstract description 4
- 238000000429 assembly Methods 0.000 claims abstract description 4
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 10
- 238000009413 insulation Methods 0.000 claims description 8
- 230000037452 priming Effects 0.000 claims description 6
- 230000005540 biological transmission Effects 0.000 claims description 3
- 239000007769 metal material Substances 0.000 claims description 3
- 238000004804 winding Methods 0.000 claims description 3
- 238000000034 method Methods 0.000 claims description 2
- 238000007599 discharging Methods 0.000 description 9
- 210000004027 cell Anatomy 0.000 description 6
- 230000000694 effects Effects 0.000 description 6
- 239000000243 solution Substances 0.000 description 5
- 238000005057 refrigeration Methods 0.000 description 4
- 230000002457 bidirectional effect Effects 0.000 description 3
- 230000006835 compression Effects 0.000 description 3
- 238000007906 compression Methods 0.000 description 3
- 239000012141 concentrate Substances 0.000 description 3
- 229910001873 dinitrogen Inorganic materials 0.000 description 3
- 238000001816 cooling Methods 0.000 description 2
- 238000013461 design Methods 0.000 description 2
- 238000001514 detection method Methods 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 230000008859 change Effects 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 230000005611 electricity Effects 0.000 description 1
- 238000005265 energy consumption Methods 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 238000004904 shortening Methods 0.000 description 1
- 238000002791 soaking Methods 0.000 description 1
- 230000003068 static effect Effects 0.000 description 1
- 230000004083 survival effect Effects 0.000 description 1
- 238000012546 transfer Methods 0.000 description 1
Classifications
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
- B65D81/00—Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents
- B65D81/18—Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents providing specific environment for contents, e.g. temperature above or below ambient
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
- B65D25/00—Details of other kinds or types of rigid or semi-rigid containers
- B65D25/02—Internal fittings
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
- B65D25/00—Details of other kinds or types of rigid or semi-rigid containers
- B65D25/20—External fittings
- B65D25/24—External fittings for spacing bases of containers from supporting surfaces, e.g. legs
Landscapes
- Engineering & Computer Science (AREA)
- Mechanical Engineering (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
The invention relates to the field of medical transportation, in particular to a stem cell injection transportation and preservation device, which comprises a transportation cabinet body, a nitrogen spraying device arranged on the back side of the transportation cabinet body, and a liquid nitrogen tank and a gas storage tank which are respectively arranged on the left side and the right side of the transportation cabinet body; a plurality of preservation assemblies are arranged in the transportation cabinet body; a control panel is arranged on the outer side of the transportation cabinet body; the liquid nitrogen tank is communicated with the nitrogen spraying device; each preservation component is respectively communicated with a liquid nitrogen tank and a gas storage tank; the top end of the transportation cabinet body is provided with a pressure discharge device which is respectively communicated with the transportation cabinet body and the air storage tank; the nitrogen spraying device can be vertically and movably arranged in the transportation cabinet body in a translation way through a power device; the pressure detector and the temperature detector are arranged in the transport cabinet body and are electrically connected with the control panel, the multi-layer stem cell injection can be refrigerated layer by layer, the temperature of a refrigerating space is effectively guaranteed by matching with other measures such as a cold guide pipe and the like, and the stability of all stem cell injections is further effectively guaranteed in transportation.
Description
Technical Field
The invention relates to the field of medical transportation, in particular to a stem cell injection transportation and preservation device.
Background
The stem cells can be differentiated into cells with multiple functions under certain conditions, and the cells are called as universal cells in medicine, so that very strict requirements are imposed on transportation and storage of stem cell injection, the activity of the stem cells must be guaranteed during transportation and storage, the existing storage method of the stem cell injection is to put the stem cells in a bearing box and put the stem cells into liquid nitrogen for soaking or adopt a liquid nitrogen spraying cooling method, and the temperature and pressure required by the survival of the stem cells are difficult to accurately control in the prior art, so that the activity of the stem cells is reduced and even the stem cells die.
through retrieval, the Chinese patent number: CN201721406183, which comprises a box body, a heat insulation board, a header pipe, a solenoid valve, an exhaust pipe, a temperature control switch, a movable plate, a preservation box, a bidirectional screw rod and a honeycomb rubber clamping board, wherein the header pipe is arranged inside the box body, the solenoid valve is arranged at the right end of the header pipe, the exhaust pipe is arranged at the right end of the solenoid valve, the temperature control switch is arranged inside the exhaust pipe, the heat insulation board is arranged at the right end of the exhaust pipe, the design can accurately refrigerate different preservation boxes, the preservation box is arranged at the upper end of the movable plate, the bidirectional screw rod is arranged inside the preservation box, the honeycomb rubber clamping board is arranged on the bidirectional screw rod, the honeycomb rubber clamping board is arranged at the bottom inside the preservation box, the design can clamp different specifications of stem cell injections, and realize that the same device can place different stem cell injections, the energy consumption is reduced, the application range is improved, and the reliability is high.
The disadvantage of the above scheme is that the scheme aims at only limiting clamping of stem cell injection solutions with different specifications, and the description of timely refrigeration is ambiguous, so that how to effectively refrigerate all stem cell injection solutions in time cannot be obtained, so that the refrigeration temperatures of the stem cell injection solutions at the upper part and the lower part are different, the whole refrigeration effect is not ideal, and even the activity of part of the stem cell injection solutions is reduced.
disclosure of Invention
The invention aims to provide a stem cell injection transportation and preservation device aiming at the defects of the prior art.
In order to solve the above problems, the present invention provides the following technical solutions: a stem cell injection transportation and preservation device comprises a transportation cabinet body, a nitrogen spraying device arranged on the back side of the transportation cabinet body, and a liquid nitrogen tank and a gas storage tank which are respectively arranged on the left side and the right side of the transportation cabinet body; a plurality of preservation assemblies with the same structure are arranged in the transportation cabinet body from top to bottom; the outer side of the transportation cabinet body is also provided with a control panel; the liquid nitrogen tank is communicated with the nitrogen spraying device; each preservation component is respectively communicated with a liquid nitrogen tank and a gas storage tank; the top end of the transportation cabinet body is provided with a pressure discharge device which is respectively communicated with the transportation cabinet body and the gas storage tank; the nitrogen spraying device can be vertically and movably arranged in the transportation cabinet body in a translation way through a power device; the internal pressure detector and the thermodetector that are used for detecting its inside pressure value and temperature value of installing of transport cabinet to both all with control panel electric connection.
Further, the preservation assembly comprises a bearing plate, a placing frame and a cooling guide pipe which is arranged at the bottom of the placing frame in a winding manner; the left side and the right side of the bearing plate are respectively fixedly connected with the left side and the right side in the transportation cabinet body, and the two sides of the bearing plate are both provided with notches for the nitrogen spraying device to vertically move; the back side of the bearing plate is spaced from the back side in the conveying cabinet body, a groove which is sunken downwards is formed in the center of the bearing plate, two sliding rails are symmetrically arranged in the groove, and two sides of the bottom of the placing frame are movably matched with the sliding rails respectively.
Furthermore, four side edges of the placing frame are all of a grid structure; the bottoms of the cold guide pipe and the placing frame are made of metal materials; a first main pipe and a second main pipe are respectively arranged outside the left side and the right side of the transportation cabinet body and are close to the front side of the transportation cabinet body; one end of the cold guide pipe close to the front side of the transportation cabinet body is communicated with the first main pipe through a first hose, and the other end of the cold guide pipe is communicated with the second main pipe through a second hose; the liquid nitrogen tank is communicated with the first main pipe through an input pump; the air storage tank is communicated with the second main pipe through the output pump.
further, the power device comprises a lifting electric cylinder arranged outside the transport cabinet body and a translation electric cylinder arranged in the transport cabinet body through a support plate; the support plate is vertically and movably matched with the back side in the transportation cabinet body; the output end of the lifting electric cylinder is connected with the support plate; the nitrogen spraying device comprises an extension main board and a rectification bin, wherein one side of the rectification bin is hinged to the front side of the extension main board through a rotating shaft; the other side of the rectifying bin is open; one end of the extension main board is fixedly connected with the output end of the translation electric cylinder; the top of the extension main board is provided with a flow guide assembly communicated with the interior of the rectification bin, the output end of the translation electric cylinder is further provided with a heat preservation box, a driving motor is arranged in the heat preservation box, and a main shaft of the driving motor is in transmission connection with the rotating shaft.
Furthermore, the flow guide assembly comprises a third main pipe and a plurality of branch pipes arranged on the third main pipe, and each branch pipe is communicated with the interior of the rectifying bin through a third hose; the self priming pump is installed in the outside of the transportation cabinet body, and the input of self priming pump passes through fourth hose and liquid nitrogen container intercommunication, and the output of self priming pump passes through fifth hose and third house steward intercommunication.
Furthermore, a plurality of openable cabinet doors are arranged on the front side of the transportation cabinet body, and each cabinet door corresponds to one placing frame; the inboard of every cabinet door all is provided with a hollow post, and when the cabinet door was in the closed condition, hollow post was just to the frame of placing of its position, and hollow post is close to can be movable insert in the one end of placing the frame and is equipped with the conflict pole, and the conflict pole passes through the hole bottom elastic connection of spring and hollow post.
Further, all set up the heat-insulating groove of circuitous setting in the left and right sides of the transportation cabinet body, the top symmetry of the transportation cabinet body is seted up two water injection holes that are used for respectively and communicate in the heat-insulating groove.
Further, the pressure discharging device comprises a pressure discharging pump, a pressure discharging pipe and a pressure discharging pipe, the input end of the pressure discharging pump is communicated with the interior of the transportation cabinet through the pressure discharging pipe, an air valve is arranged on the pressure discharging pipe, and the output end of the pressure discharging pump is communicated with an air storage tank through the pressure discharging pipe.
Furthermore, a plurality of self-locking universal wheels are arranged at the bottom of the transportation cabinet body.
Has the advantages that: the invention relates to a cell injection transportation and preservation device, wherein a placing frame is used for placing bagged stem cell injection; the cabinet door is manually opened, the placing frame is pulled to move out by means of the sliding rail, and stem cell injection liquid is conveniently placed in the placing frame; considering the jolt in transportation, after the cabinet door is closed, the contact rod contacts the placing frame, the contact force of the contact rod and the contact rod is applied, and the contact rod is in a compression state and contacts with the placing frame by compressing the spring to shrink; further ensuring that the placing frame cannot shake randomly in the transportation cabinet body, thereby influencing the internal structure of the transportation cabinet or spraying nitrogen; then, considering that the left side and the right side are both provided with the air storage tank and the liquid nitrogen tank, high temperature is easy to generate during work, and the external temperature during transportation is considered, so that cold water is injected into the heat insulation tank from the water injection hole in advance, and heat energy generated by external work or external heat energy cannot be led into the transportation cabinet body, thereby further ensuring that the temperature in the transportation cabinet body can be within a controllable range; after the placing frames are filled with the stem cell injection liquid and the cabinet door is also closed, the driving motor is used for driving the rectifying bin to rotate around the rotating shaft to an inclined posture, the power transfer cylinder is used for driving the rectifying bin to move above a certain placing frame, namely, nitrogen is sprayed on the placing frame, after the horizontal movement reaches an extreme position, the placing frame descends from the position through the lifting electric cylinder, and after the placing frame descends to the other layer, the horizontal movement is continued through the translation electric cylinder, namely, the nitrogen is sprayed on the placing frame; the step in the spraying is that the self-priming pump transmits the nitrogen in the liquid nitrogen tank to the third main pipe, then the nitrogen is sent into the rectifying bin by the branch pipes and the third hose, and finally the nitrogen is sprayed out from the opening of the rectifying bin, the length of the rectifying bin is the same as the specification of the placing frame, so that the rectifying bin can concentrate the nitrogen to be sprayed between certain specifications, and the nitrogen is forced to directly contact the stem cell injection liquid in the placing frame after being sprayed, so that the nitrogen is directly and fully contacted with the dry cell injection liquid; then the input pump inputs the nitrogen in the liquid nitrogen tank into each cold guide pipe, and the nitrogen fully contacts with the cold guide pipes through the roundabout cold guide pipes, so that the cold guide pipes are cooled, and the placing frame is convenient to guide the cold; the nitrogen passing through the cold guide pipe can be sucked into the gas storage tank by the output pump, so that the air pressure value in the cold guide pipe is ensured to be in a stable state and the cold guide pipe is ensured to be in a low-temperature range value capable of bearing; the pressure detector and the temperature detector detect the air pressure value and the temperature value in the transport cabinet body constantly, when the temperature is high, the temperature detector transmits a detection signal to the control panel, the control panel starts to enable the nitrogen spraying device to convey nitrogen into the transport cabinet body, and the nitrogen spraying device stops conveying nitrogen once in the cold guide pipe, so that the stability of the cold guide pipe is ensured; when the air pressure value in the transportation cabinet is overlarge, the pressure detector transmits a signal to the control panel; the control panel is internally provided with modules such as a control chip and the like, then the control panel controls the air valve to be opened, and then partial air pressure in the transport cabinet is pumped out to the air storage tank through the exhaust and pressure pump.
Drawings
FIG. 1 is a first perspective view of the present invention;
FIG. 2 is a schematic perspective view of the present invention;
FIG. 3 is a plan sectional view of the present invention;
FIG. 4 is a first perspective view of the present invention;
FIG. 5 is an enlarged view taken at A in FIG. 4;
FIG. 6 is a second perspective sectional view of the present invention;
FIG. 7 is an enlarged view at B in FIG. 6;
FIG. 8 is a schematic view of the split structure of the present invention;
FIG. 9 is a third perspective sectional view of the present invention;
Description of reference numerals: the transportation cabinet body 1, cabinet door 1a, hollow post 1b, support feeler lever 1c, spring 1d, heat-insulating groove 1k, water injection hole 1m, from locking-type universal wheel 1 q.
Pressure discharge device 2, pressure discharge pump 2a, pressure suction pipe 2b, pneumatic valve 2c, pressure discharge pipe 2 d.
a liquid nitrogen tank 3 and an input pump 3 a.
An air storage tank 4 and an output pump 4 a.
Preserve subassembly 5, bearing board 5a, breach 5b, recess 5c, slide rail 5d, place frame 5e, lead cold pipe 5g, first hose 5q, second hose 5 m.
a first manifold 6, a second manifold 6 a.
The device comprises a power device 7, a lifting electric cylinder 7a, a support plate 7b, a translation electric cylinder 7v, a heat preservation box 7c and a driving motor 7 d.
Spout nitrogen device 8, extend mainboard 8a, pivot 8b, rectification storehouse 8 c.
a third manifold 9, a branch 9a, a self-priming pump 9b, and a fourth hose 9 c.
A pressure detector 10 and a temperature detector 11.
Detailed Description
The following detailed description of specific embodiments of the present invention is made with reference to the accompanying drawings and examples:
Referring to fig. 1 to 9, the transportation and preservation device for stem cell injection comprises a transportation cabinet body 1, a nitrogen spraying device 8 arranged at the back side of the transportation cabinet body 1, and a liquid nitrogen tank 3 and a gas storage tank 4 respectively arranged at the left side and the right side of the transportation cabinet body 1; a plurality of preservation assemblies 5 with the same structure are arranged in the transportation cabinet body 1 from top to bottom; a control panel is also arranged on the outer side of the transportation cabinet body 1; the liquid nitrogen tank 3 is communicated with a nitrogen spraying device 8; each preservation component 5 is respectively communicated with the liquid nitrogen tank 3 and the gas storage tank 4; the top end of the transportation cabinet body 1 is provided with a pressure discharge device 2, and the pressure discharge device 2 is respectively communicated with the transportation cabinet body 1 and the gas storage tank 4; the nitrogen spraying device 8 can be vertically and movably arranged in the transportation cabinet body 1 in a translation way through the power device 7; the transportation cabinet body 1 is internally provided with a pressure detector 10 and a temperature detector 11 which are used for detecting the internal pressure value and the internal temperature value of the transportation cabinet body, and the two are electrically connected with the control panel.
The preservation assembly 5 comprises a bearing plate 5a, a placing frame 5e and a cold guide pipe 5g which is arranged at the bottom of the placing frame 5e and is arranged in a winding way; the left side and the right side of the bearing plate 5a are respectively and fixedly connected with the left side and the right side in the transportation cabinet body 1, and the two sides of the bearing plate 5a are both provided with notches 5b for the nitrogen spraying device 8 to vertically move; a space is reserved between the back side of the bearing plate 5a and the back side in the transportation cabinet body 1, a groove 5c which is sunken downwards is formed in the center of the bearing plate 5a, two sliding rails 5d are symmetrically arranged in the groove 5c, and two sides of the bottom of the placing frame 5e are respectively in movable fit with one sliding rail 5 d; the placing frame 5e is used for placing the bagged stem cell injection; a distance is reserved between the back side of the bearing plate 5a and the back side in the transportation cabinet body 1, and the distance can be used for enabling the power device 7 to vertically move synchronously along with the nitrogen spraying device 8 in the transportation cabinet body 1; lead the effect of cold pipe 5g and lie in making to lead cold pipe 5g self to become cold through the nitrogen gas in liquid nitrogen container 3, through leading cold pipe 5g with place the contact of frame 5e bottom, leading-in placing frame 5e of giving of cold medium for place the stem cell injection in frame 5e and be in the low temperature state, slide rail 5d is used in and can will place frame 5e and take out from the freezer is internal, is convenient for put into stem cell injection.
Four side edges of the placing frame 5e are all of a grid structure; the bottoms of the cold guide pipe 5g and the placing frame 5e are both made of metal materials; a first main pipe 6 and a second main pipe 6a are respectively arranged outside the left side and the right side of the transportation cabinet body 1 and are both close to the front side of the transportation cabinet body 1; one end of the cold guide pipe 5g close to the front side of the transportation cabinet body 1 is communicated with the first main pipe 6 through a first hose 5q, and the other end of the cold guide pipe 5g is communicated with the second main pipe 6a through a second hose 5 m; the liquid nitrogen tank 3 is communicated with a first main pipe 6 through an input pump 3 a; the air storage tank 4 is communicated with a second manifold 6a through an output pump 4 a; the material of the cold guide pipe 5g ensures that the cold guide effect is better; the four side edges of the placing frame 5e are of a grid structure, so that nitrogen can smoothly flow in the transportation cabinet body 1 through the grid structure, and the placing frame 5e of the grid structure can fully move vertically in the transportation cabinet body 1 through the gaps 5b and the spaces; the input pump 3a is mainly used for inputting nitrogen in the liquid nitrogen tank 3 into each cold guide pipe 5g through the first header pipe 6, and the nitrogen fully contacts with the cold guide pipes 5g through the roundabout cold guide pipes 5g, so that the cold guide pipes 5g are cooled, and the placing frame 5e is convenient to conduct cold; the nitrogen passing through the cold guide pipe 5g is sucked into the gas storage tank 4 by the output pump 4a, so that the gas pressure value in the cold guide pipe 5g is in a stable state and the cold guide pipe 5g is in a low-temperature range value capable of bearing; electromagnetic valves are respectively arranged between the input pump 3a and the output pump 4a, and between the liquid nitrogen tank 3 and the gas storage pipe, and the electromagnetic valves are mainly used for cutting off the mutual on-off and properly adjusting the flow.
The power device 7 comprises a lifting electric cylinder 7a arranged outside the transport cabinet body 1 and a translation electric cylinder 7v arranged in the transport cabinet body 1 through a support plate 7 b; the support plate 7b is vertically and movably matched with the back side in the transportation cabinet body 1; the output end of the lifting electric cylinder 7a is connected with the support plate 7 b; the nitrogen spraying device 8 comprises an extension main board 8a and a rectification bin 8c, wherein one side of the rectification bin is hinged to the front side of the extension main board 8a through a rotating shaft 8 b; the other side of the rectifying bin 8c is open; one end of the extension main plate 8a is fixedly connected with the output end of the translation electric cylinder 7 v; a flow guide assembly communicated with the interior of the rectification bin 8c is installed at the top of the extension main board 8a, a heat preservation box 7c is further arranged at the output end of the translation electric cylinder 7v, a driving motor 7d is arranged in the heat preservation box 7c, and a main shaft of the driving motor 7d is in transmission connection with the rotating shaft 8 b; the driving motor 7d is used for driving the rectifying bin 8c to rotate around the rotating shaft 8b, and the purpose is as follows: the rectifying bin 8c is in a working state; namely, when the nitrogen is sprayed, the nitrogen is obliquely matched with the extension main board 8a, and the inclination angle is in an interval of 125-145 degrees; the rectifying bin 8c is in a normal state; namely, when the power device 7 is in a static state or moves along with the power device, the power device is matched with the extension main board 8a at a right angle; the right-angle fit aims at shortening the length between the two, can adapt to the distance between the gaps 5b, and is convenient for vertically moving in the transport cabinet body 1 through the lifting electric cylinder 7a, the translation electric cylinder 7v is used for driving the rectifying bin 8c to move above a certain preservation assembly 5, namely nitrogen is sprayed in a placing frame 5e in the preservation assembly 5, so that the rectifying bin 8c is circuitous in the transport cabinet body 1 in phase change; it is guaranteed to correspond to each placement frame 5 e.
The flow guide assembly comprises a third main pipe 9 and a plurality of branch pipes 9a arranged on the third main pipe 9, and each branch pipe 9a is communicated with the interior of the rectifying bin 8c through a third hose; a self-sucking pump 9b is installed on the outer side of the transportation cabinet body 1, the input end of the self-sucking pump 9b is communicated with the liquid nitrogen tank 3 through a fourth hose 9c, and the output end of the self-sucking pump 9b is communicated with a third main pipe 9 through a fifth hose; the self-priming pump 9b transmits nitrogen in the liquid nitrogen tank 3 to the third header pipe 9 through a fifth hose, the nitrogen is sent into the rectifying bin 8c through a plurality of branch pipes 9a and the third hose, and finally is sprayed out from an opening of the rectifying bin 8c, the length of the rectifying bin 8c is the same as the specification of the placing frame 5e, so that the rectifying bin 8c can concentrate the nitrogen to be sprayed between certain specifications, and the nitrogen is forced to be sprayed and then directly contacted with the stem cell injection liquid in the placing frame 5e, so that the nitrogen is directly and fully contacted with the nitrogen; an electromagnetic valve is arranged on the fourth hose 9c for controlling the flow.
a plurality of openable cabinet doors 1a are arranged on the front side of the transportation cabinet body 1, and each cabinet door 1a corresponds to one placing frame 5 e; the inner side of each cabinet door 1a is provided with a hollow column 1b, when the cabinet door 1a is in a closed state, the hollow column 1b is over against a placing frame 5e at the position of the hollow column 1b, a contact rod 1c is movably inserted into one end, close to the placing frame 5e, of the hollow column 1b, and the contact rod 1c is elastically connected with the hole bottom of the hollow column 1b through a spring 1 d; considering the bumping in transportation, after the cabinet door 1a is closed, the contact rod 1c contacts the placing frame 5e, the contact force between the contact rod 1c and the placing frame 1 e is applied, the compression spring 1d is contracted, the placing frame 5e is ensured not to shake randomly in the transportation cabinet body 1 to influence the internal structure or the nitrogen spraying work,
The left side and the right side of the transportation cabinet body 1 are both internally provided with circuitous heat insulation grooves 1k, and the top of the transportation cabinet body 1 is symmetrically provided with two water injection holes 1m which are respectively communicated with the inside of one heat insulation groove 1 k; the left and right sides all has gas holder 4 and liquid nitrogen container 3, and the during operation easily produces high temperature to outside temperature when considering the transportation is injected cold water to heat-insulating tank 1k in following water injection hole 1m in advance, guarantees in heat energy or the outside heat energy that outside work produced can not lead to the transportation cabinet body 1, has further ensured that the temperature in the transportation cabinet body 1 can be in a steerable within range.
The pressure discharge device 2 comprises a pressure discharge pump 2a, a pressure discharge pipe 2b and a pressure discharge pipe 2d, the input end of the pressure discharge pump 2a is communicated with the inside of the transportation cabinet body 1 through the pressure discharge pipe 2b, an air valve 2c is arranged on the pressure discharge pipe 2b, and the output end of the pressure discharge pump 2a is communicated with an air storage tank 4 through the pressure discharge pipe 2 d; when the density of nitrogen gas is too big in the transportation cabinet body 1, atmospheric pressure increases, stops to input nitrogen gas this moment to the transportation cabinet body 1 in, and pneumatic valve 2c work, draws away to the gas holder 4 in with the partial atmospheric pressure of the transportation cabinet body 1 through the exhaust pump 2 a.
A plurality of self-locking universal wheels 1q are arranged at the bottom of the transportation cabinet body 1; the universal wheels are convenient for manual massage operation. The working principle is as follows: the placing frame 5e is used for placing the bagged stem cell injection; the cabinet door 1a is opened manually, the placing frame 5e is pulled to move out by means of the sliding rail 5d, and stem cell injection liquid is conveniently placed in the placing frame; considering the jolt in transportation, after the cabinet door 1a is closed, the contact rod 1c contacts the placing frame 5e, the contact rod 1c is contacted with the contact force, and the contact rod 1c is in a compression state and is contacted with the placing frame 5e by compressing the spring 1d to contract; further ensuring that the placing frame 5e cannot shake randomly in the transportation cabinet body 1, thereby influencing the internal structure or spraying nitrogen; then, considering that the left side and the right side are both provided with the gas storage tank 4 and the liquid nitrogen tank 3, high temperature is easy to generate during work, and the external temperature during transportation is considered, cold water is injected into the heat insulation groove 1k from the water injection hole 1m in advance, so that heat energy generated by external work or external heat energy cannot be led into the transportation cabinet body 1, and the temperature in the transportation cabinet body 1 is further ensured to be within a controllable range; after the placing frame 5e is filled with the stem cell injection liquid and the cabinet door 1a is also closed, the driving motor 7d is used for driving the rectifying bin 8c to rotate around the rotating shaft 8b to an inclined posture, the electricity moving cylinder is used for driving the rectifying bin 8c to move above a certain placing frame 5e, namely nitrogen is sprayed on the placing frame 5e, after the horizontal movement is carried out to an extreme position, the placing frame is descended from the position through the lifting electric cylinder 7a to another layer of placing frame 5e, the horizontal movement is continued through the translation electric cylinder 7v, namely the nitrogen is sprayed on the placing frame 5 e; the step in the spraying is that the self-priming pump 9b transmits the nitrogen in the liquid nitrogen tank 3 to the third main pipe 9, then the nitrogen is sent into the rectifying bin 8c through the branch pipes 9a and the third hose, and finally the nitrogen is sprayed out from the opening of the rectifying bin 8c, the length of the rectifying bin 8c is the same as the specification of the placing frame 5e, so that the rectifying bin 8c can concentrate the nitrogen to be sprayed between certain specifications, and the nitrogen is forced to directly contact with the dry cell injection in the placing frame 5e after being sprayed, so that the nitrogen is directly and fully contacted with the nitrogen; then the input pump 3a inputs the nitrogen in the liquid nitrogen tank 3 into each cold guide pipe 5g, and the nitrogen fully contacts with the cold guide pipes 5g through the roundabout cold guide pipes 5g, so that the cold guide pipes 5g are cooled, and the placing frame 5e is convenient to conduct cold; the nitrogen passing through the cold guide pipe 5g is sucked into the gas storage tank 4 by the output pump 4a, so that the gas pressure value in the cold guide pipe 5g is in a stable state and the cold guide pipe 5g is in a low-temperature range value capable of bearing; the pressure detector 10 and the temperature detector 11 detect the air pressure value and the temperature value in the transportation cabinet body 1 at any time, when the temperature is high, the temperature detector 11 transmits a detection signal to the control panel, the control panel starts to enable the nitrogen spraying device 8 to convey nitrogen into the transportation cabinet body 1, and the nitrogen conveying device stops after the nitrogen is conveyed into the cold guide pipe 5g for one time, so that the stability of the cold guide pipe 5g is ensured; when the air pressure value in the transportation cabinet body 1 is overlarge, the pressure detector 10 transmits a signal to the control panel; the control panel is internally provided with modules such as a control chip and the like, then the control panel controls the air valve 2c to be opened, then partial air pressure in the transportation cabinet body 1 is pumped out to the air storage tank 4 through the pressure exhaust pump 2a, the stem cell injection can be put into the cabinet door 1a layer by layer in a matching mode, after each layer is put into the cabinet door, the cabinet door 1a on the corresponding layer is closed, and the internal device performs refrigeration work immediately.
The above description is only a preferred embodiment of the present invention, and is not intended to limit the technical scope of the present invention, so that any minor modifications, equivalent changes and modifications made to the above embodiment according to the technical spirit of the present invention are within the technical scope of the present invention.
Claims (9)
1. A stem cell injection transportation and preservation device comprises a transportation cabinet body (1), and a liquid nitrogen tank (3) and a gas storage tank (4) which are respectively arranged on the left side and the right side of the transportation cabinet body (1); a plurality of preservation assemblies (5) with the same structure are arranged in the transportation cabinet body (1) from top to bottom; a control panel is also arranged on the outer side of the transportation cabinet body (1); each preservation component (5) is respectively communicated with the liquid nitrogen tank (3) and the gas storage tank (4); a pressure detector (10) and a temperature detector (11) for detecting the internal pressure value and temperature value of the transportation cabinet body (1) are arranged in the transportation cabinet body, and the two are electrically connected with the control panel; the method is characterized in that: the nitrogen spraying device (8) is arranged on the back side of the transportation cabinet body (1), and the liquid nitrogen tank (3) is communicated with the nitrogen spraying device (8); the top end of the transportation cabinet body (1) is provided with a pressure discharge device (2), and the pressure discharge device (2) is respectively communicated with the transportation cabinet body (1) and the air storage tank (4); the nitrogen spraying device (8) can be vertically and movably arranged in the transportation cabinet body (1) in a translation mode through the power device (7).
2. The transportation and preservation device for stem cell injection according to claim 1, wherein: the preservation component (5) comprises a bearing plate (5a), a placing frame (5e) and a cold guide pipe (5g) which is arranged at the bottom of the placing frame (5e) and is arranged in a winding way; the left side and the right side of the bearing plate (5a) are respectively fixedly connected with the left side and the right side in the transportation cabinet body (1), and gaps (5b) which can allow the nitrogen spraying device (8) to vertically move are formed in the two sides of the bearing plate (5 a); the back side of the bearing plate (5a) and the back side in the transportation cabinet body (1) are spaced, a groove (5c) which is sunken downwards is formed in the center of the bearing plate (5a), two sliding rails (5d) are symmetrically arranged in the groove (5c), and two sides of the bottom of the placement frame (5e) are respectively in movable fit with one sliding rail (5 d).
3. The transportation and preservation device for stem cell injection according to claim 2, wherein: four side edges of the placing frame (5e) are all of a grid structure; the bottoms of the cold guide pipe (5g) and the placing frame (5e) are made of metal materials; a first header pipe (6) and a second header pipe (6a) are respectively arranged outside the left side and the right side of the transportation cabinet body (1) and are close to the front side of the transportation cabinet body (1); one end of the cold guide pipe (5g) close to the front side of the transportation cabinet body (1) is communicated with the first main pipe (6) through a first hose (5q), and the other end of the cold guide pipe (5g) is communicated with the second main pipe (6a) through a second hose (5 m); the liquid nitrogen tank (3) is communicated with the first main pipe (6) through an input pump (3 a); the air storage tank (4) is communicated with the second main pipe (6a) through an output pump (4 a).
4. The transportation and preservation device for stem cell injection according to claim 1, wherein: the power device (7) comprises a lifting electric cylinder (7a) arranged outside the transportation cabinet body (1) and a translation electric cylinder (7v) arranged in the transportation cabinet body (1) through a support plate (7 b); the support plate (7b) is vertically and movably matched with the back side in the transportation cabinet body (1); the output end of the lifting electric cylinder (7a) is connected with the support plate (7 b); the nitrogen spraying device (8) comprises an extension main board (8a) and a rectification bin (8c) with one side hinged to the front side of the extension main board (8a) through a rotating shaft (8 b); the other side of the rectifying bin (8c) is open; one end of the extension main plate (8a) is fixedly connected with the output end of the translation electric cylinder (7 v); the top of the extension main board (8a) is provided with a flow guide assembly communicated with the interior of the rectification bin (8c), the output end of the translation electric cylinder (7v) is further provided with a heat preservation box (7c), the heat preservation box (7c) is internally provided with a driving motor (7d), and a main shaft of the driving motor (7d) is in transmission connection with the rotating shaft (8 b).
5. The transportation and preservation device for stem cell injection according to claim 4, wherein: the flow guide assembly comprises a third main pipe (9) and a plurality of branch pipes (9a) arranged on the third main pipe (9), and each branch pipe (9a) is communicated with the interior of the rectifying bin (8c) through a third hose; self priming pump (9b) is installed in the outside of the transportation cabinet body (1), and the input of self priming pump (9b) passes through fourth hose (9c) and liquid nitrogen container (3) intercommunication, and the output of self priming pump (9b) passes through fifth hose and third house steward (9) intercommunication.
6. The transportation and preservation device for stem cell injection according to claim 3, wherein: a plurality of openable cabinet doors (1a) are arranged on the front side of the transportation cabinet body (1), and each cabinet door (1a) corresponds to one placing frame (5 e); the inboard of every cabinet door (1a) all is provided with one hollow post (1b), and when cabinet door (1a) was in the closed condition, hollow post (1b) was just to placing frame (5e) of its position, and hollow post (1b) is close to can be movable to insert in the one end of placing frame (5e) and is equipped with to feeler lever (1c), and feeler lever (1c) passes through the hole bottom elastic connection of spring (1d) and hollow post (1 b).
7. the transportation and preservation device for stem cell injection according to claim 1, wherein: all set up circuitous heat insulation tank (1k) that sets up in the left and right sides of the transportation cabinet body (1), the top symmetry of the transportation cabinet body (1) is seted up two and is used for water injection hole (1m) with a heat insulation tank (1k) in-connection respectively.
8. the transportation and preservation device for stem cell injection according to claim 1, wherein: pressure discharge device (2) are including pressure discharge pump (2a), pressure pipe (2b) and pressure discharge pipe (2d), and the input of pressure discharge pump (2a) is through pressing pipe (2b) and transport cabinet body (1) interior intercommunication, is provided with pneumatic valve (2c) on this pressure discharge pipe (2b), and the output of pressure discharge pump (2a) is through pressing pipe (2d) and gas holder (4) intercommunication.
9. The transportation and preservation device for stem cell injection according to claim 1, wherein: the bottom of the transportation cabinet body (1) is provided with a plurality of self-locking universal wheels (1 q).
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| CN201810807519.9A CN109132219B (en) | 2018-07-21 | 2018-07-21 | Stem cell injection transportation keeps device |
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| CN201810807519.9A CN109132219B (en) | 2018-07-21 | 2018-07-21 | Stem cell injection transportation keeps device |
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| CN109132219A CN109132219A (en) | 2019-01-04 |
| CN109132219B true CN109132219B (en) | 2019-12-13 |
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| CN110550327B (en) * | 2019-10-08 | 2021-11-23 | 苏州贝康医疗器械有限公司 | Biological sample transfer container |
| CN113353456B (en) * | 2021-04-30 | 2022-12-06 | 威海见生生物技术有限公司 | Cell refrigerating box for long-distance transportation |
| CN113581616B (en) * | 2021-09-27 | 2021-12-10 | 江苏辰安泰生物医药研究院有限公司 | Energy-saving ultralow-temperature storage box for long-distance transportation of bone marrow |
| CN115416978B (en) * | 2022-10-12 | 2023-03-17 | 青岛奥克生物开发有限公司 | Biological tissue suspension type low temperature storage equipment |
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| NL6812500A (en) * | 1968-09-03 | 1970-03-05 | Freezing tunnel for freezing food products | |
| US9837293B2 (en) * | 2013-10-30 | 2017-12-05 | Taiwan Semiconductor Manufacturing Co., Ltd. | Mechanisms for charging gas into cassette pod |
| CN205027034U (en) * | 2015-09-09 | 2016-02-10 | 衢州市江氏电子科技有限公司 | Intelligent control liquid nitrogen refrigeration beer device |
| CN105857941B (en) * | 2016-04-28 | 2018-06-29 | 上海原能健康管理有限公司 | Cryopreservation tube access device |
| CN107228518A (en) * | 2017-06-04 | 2017-10-03 | 王玉杰 | Stem cell injecta transporting preservation device |
| CN207197024U (en) * | 2017-07-15 | 2018-04-06 | 科威嘉尼（江苏）制冷设备有限公司 | A kind of liquid nitrogen control system of liquid nitrogen frozen equipment |
| CN207360970U (en) * | 2017-09-28 | 2018-05-15 | 新疆维吾尔自治区人民医院 | A kind of Blood piece cryopreservation device |
| CN207476789U (en) * | 2017-10-26 | 2018-06-12 | 天津百恩生物科技有限公司 | A kind of stem cell injecta transporting preservation device |
| CN207450580U (en) * | 2017-11-15 | 2018-06-05 | 云南农业大学 | A kind of stem cell injecta transporting preservation device |
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Effective date of registration: 20210820 Address after: 241200 room 912a, comprehensive service center, Fanchang Economic Development Zone, Wuhu City, Anhui Province Patentee after: Wuhu cell star Bioengineering Research Co.,Ltd. Address before: Room 210-d8, A3 / F, Hefei Innovation Industrial Park, 800 Wangjiang West Road, high tech Zone, Hefei City, Anhui Province, 230088 Patentee before: ANHUI XIBAOZHIXING BIO-TECH Co.,Ltd. |
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