CN109118555A - The metal artifacts reduction method and system of computer tomography - Google Patents

The metal artifacts reduction method and system of computer tomography Download PDF

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CN109118555A
CN109118555A CN201810925109.4A CN201810925109A CN109118555A CN 109118555 A CN109118555 A CN 109118555A CN 201810925109 A CN201810925109 A CN 201810925109A CN 109118555 A CN109118555 A CN 109118555A
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image
corrected
computer tomography
computer
metal
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CN109118555B (en
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陈宇思
齐宏亮
徐月晋
胡洁
李翰威
吴书裕
骆毅斌
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Guangzhou Huarui Technology Co Ltd
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Guangzhou Huarui Technology Co Ltd
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    • GPHYSICS
    • G06COMPUTING; CALCULATING OR COUNTING
    • G06TIMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T11/002D [Two Dimensional] image generation
    • G06T11/003Reconstruction from projections, e.g. tomography
    • G06T11/008Specific post-processing after tomographic reconstruction, e.g. voxelisation, metal artifact correction
    • GPHYSICS
    • G06COMPUTING; CALCULATING OR COUNTING
    • G06TIMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T7/00Image analysis
    • G06T7/10Segmentation; Edge detection
    • G06T7/11Region-based segmentation
    • GPHYSICS
    • G06COMPUTING; CALCULATING OR COUNTING
    • G06TIMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T7/00Image analysis
    • G06T7/10Segmentation; Edge detection
    • G06T7/136Segmentation; Edge detection involving thresholding
    • GPHYSICS
    • G06COMPUTING; CALCULATING OR COUNTING
    • G06TIMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00Indexing scheme for image analysis or image enhancement
    • G06T2207/30Subject of image; Context of image processing
    • G06T2207/30004Biomedical image processing
    • G06T2207/30008Bone

Abstract

This application involves a kind of metal artifacts reduction method and systems of computer tomography.The described method includes: obtaining computer tomography image to be corrected, it treats and belongs to the regions of bone tissue intensity value ranges in correcting computer tomographic imaging image and be split, obtain bone segmentation area image, initial prior image is obtained according to computer tomography image to be corrected, final prior image is obtained according to computer tomography image to be corrected, bone segmentation area image and initial prior image, correcting computer tomographic imaging image is obtained according to final prior image and computer tomography image to be corrected.In final prior image include bone tissue information in this method, obtains the higher final prior image of accuracy, the accuracy of metal artifacts reduction can be improved.

Description

The metal artifacts reduction method and system of computer tomography
Technical field
This application involves Computed tomography fields, pseudo- more particularly to a kind of metal of computer tomography Shadow bearing calibration, computer tomography metal artifacts reduction system, computer equipment and storage medium.
Background technique
In medical computer tomography (Computed Tomography, CT) imaging, since position implantation is imaged in patient Metal has very high Decay Rate to X-ray, and there are serious measurement errors for the data that detector receives, and causes computer disconnected Contain apparent metal artifacts in layer image, seriously affects the quality of computer tomography image.
The metal artifacts reduction method of computer tomography image mainly includes iterative method and projection interpolation method.Iterative method Due to iteration time-consuming, iterative parameter need to be adjusted, application is restricted.Interpolation method is projected, basic ideas are to data for projection figure Metal information as in carries out interpolation using the nonmetallic information at its both ends and rebuilds to obtain computer tomography image again, but not Can effective calibration metal artifact, or even new artifact can be brought into due to interpolation error.
Projection interpolation method is improved, preferable metal artifacts reduction effect is obtained based on the modified method of prior model Fruit, but still remain limitation.Such as in conventional methods where, using multi-threshold segmentation method, by specifying multiple threshold values manually, will scheme Other regions as removing metallic region are divided into air, muscle and bone, and every class loading is set to single pixel value;But it is existing not Foot is: specifying multiple threshold values to need to adjust repeatedly just and can find suitable threshold value and carry out tissue class division manually, due to metal The CT Distribution value range of artifact may in air, muscle and each region of bone, cause should be soft tissue region, by Metal artifacts, which seriously affect, is divided into other regions, causes building prior image accuracy low.
Summary of the invention
Based on this, it is necessary to be directed to above-mentioned prior image accuracy low technical problem, provide a kind of computer tomography Metal artifacts reduction method and system.
A kind of metal artifacts reduction method of computer tomography, comprising the following steps:
Obtain computer tomography image to be corrected;
It treats and belongs to the regions of bone tissue intensity value ranges in correcting computer tomographic imaging image and be split, obtain bone Tissue segmentation area image;
Initial prior image is obtained according to computer tomography image to be corrected;
It is obtained according to computer tomography image to be corrected, bone segmentation area image and initial prior image final Prior image;
Correcting computer tomographic imaging image is obtained according to final prior image and computer tomography image to be corrected.
In one embodiment, according to computer tomography image to be corrected, bone segmentation area image and initial Prior image obtains the step of final prior image, comprising the following steps:
Binary conversion treatment and filtering processing are successively carried out to bone segmentation area image, obtain bone tissue processing image;
It handles image according to bone tissue computer tomography image to be corrected and initial prior image are weighted and are melted It closes, obtains final prior image.
In one embodiment, binary conversion treatment and filtering processing are successively carried out to bone segmentation area image, obtained Bone tissue handles the step of image, comprising the following steps:
It sets the pixel value of pixel in the region for belonging to bone tissue intensity value ranges in bone segmentation area image to 1,0 is set by the pixel value of remaining pixel, obtains bone tissue binary image;
According toBone tissue binary image is filtered, is obtained at bone tissue Image is managed,
Wherein,
W2(i, j) is the pixel that bone tissue handles image the i-th row jth column, and F (i, j) is the judgement of the pixel of the i-th row jth column Condition, W1(i+a, j+b) is the pixel of bone tissue binary image the i-th+a row jth+b column, and g () is the filtering square of n × n size Battle array, n is odd number, and the numerical value of filtering matrix is made of 0 and 1,It is the of filtering matrixRow TheThe element of column, i and j are respectively positive integer, and a is the first increment, and b is the second increment.
In one embodiment, image is handled for computer tomography image to be corrected and initial priori according to bone tissue The step of image is weighted fusion, obtains final prior image, comprising the following steps:
According to I_prior2 (i, j)=I_original (i, j) × W2(i,j)+I_prior1(i,j)×(1-W2(i,j)) It is weighted fusion, obtains final prior image,
Wherein, I_prior2 (i, j) be final prior image the i-th row jth column pixel, I_original (i, j) be to The pixel of correcting computer tomographic imaging image the i-th row jth column, W2(i, j) is the picture that bone tissue handles image the i-th row jth column Element, I_prior1 (i, j) are the pixel of initial prior image the i-th row jth column, and i and j are respectively positive integer.
In one embodiment, the region for belonging to bone tissue intensity value ranges in correcting computer tomographic imaging image is treated The step of being split, obtaining bone segmentation area image, comprising the following steps:
According to Bone segmentation area image is obtained,
Wherein, I_bone_artifact (i, j) is the pixel of bone segmentation area image the i-th row jth column, I_ Original (i, j) is the pixel of computer tomography image the i-th row jth to be corrected column, T1For the judgement threshold of metal information Value, T2For the judgment threshold of bone tissue information, T2<T1, i and j are respectively positive integer.
In one embodiment, the step of initial prior image being obtained according to computer tomography image to be corrected, packet Include following steps:
It treats metallic region in correcting computer tomographic imaging image to be split, obtains the metal for containing only metal information Cut zone image;
Correcting computer tomographic imaging image is treated respectively and metal cut zone image carries out forward projection, and respectively To data for projection to be corrected and metal shadowing's data;
The metallic region that data for projection to be corrected is determined according to metal shadowing's data, according to the metal of data for projection to be corrected Data outside the both ends of region, the metallic region for treating corrected projection data carry out Interpolate estimation, obtain data for projection to be corrected Intermediate corrected projection data after removing metal information;
First is obtained according to intermediate corrected projection data and rebuilds computer tomography image, and it is disconnected to rebuild computer to first Layer image is filtered, and obtains initial prior image.
In one embodiment, correction is obtained according to final prior image and computer tomography image to be corrected to calculate The step of machine tomographic imaging image, comprising the following steps:
Forward projection is carried out to final prior image, prior image data for projection is obtained, according to prior image data for projection The metallic region for treating corrected projection data carries out interpolation correction, obtains corrected projection data;
According to corrected projection data obtain second rebuild computer tomography image, by second rebuild computerized tomography at As image and metal cut zone image co-registration, correcting computer tomographic imaging image is obtained.
A kind of metal artifacts reduction system of computer tomography, comprising:
Image collection module to be corrected, for obtaining computer tomography image to be corrected;
Bone segmentation area image obtains module, belongs to bone tissue for treating in correcting computer tomographic imaging image The region of intensity value ranges is split, and obtains bone segmentation area image;
Initial prior image obtains module, for obtaining initial priori figure according to computer tomography image to be corrected Picture;
Final prior image obtains module, for according to computer tomography image to be corrected, bone segmentation region Image and initial prior image obtain final prior image;
Image collection module is corrected, for obtaining school according to final prior image and computer tomography image to be corrected Positive computer tomography image.
A kind of computer equipment can be run on a memory and on a processor including memory, processor and storage Computer program, processor perform the steps of when executing computer program
Obtain computer tomography image to be corrected;
It treats and belongs to the regions of bone tissue intensity value ranges in correcting computer tomographic imaging image and be split, obtain bone Tissue segmentation area image;
Initial prior image is obtained according to computer tomography image to be corrected;
It is obtained according to computer tomography image to be corrected, bone segmentation area image and initial prior image final Prior image;
Correcting computer tomographic imaging image is obtained according to final prior image and computer tomography image to be corrected.
A kind of computer readable storage medium is stored thereon with computer program, when computer program is executed by processor It performs the steps of
Obtain computer tomography image to be corrected;
It treats and belongs to the regions of bone tissue intensity value ranges in correcting computer tomographic imaging image and be split, obtain bone Tissue segmentation area image;
Initial prior image is obtained according to computer tomography image to be corrected;
It is obtained according to computer tomography image to be corrected, bone segmentation area image and initial prior image final Prior image;
Correcting computer tomographic imaging image is obtained according to final prior image and computer tomography image to be corrected.
The metal artifacts reduction method and system of above-mentioned computer tomography includes bone tissue in final prior image Information obtains the higher final prior image of accuracy, the accuracy of metal artifacts reduction can be improved.
Detailed description of the invention
Fig. 1 is the internal structure chart of computer equipment in one embodiment;
Fig. 2 is the flow chart of the metal artifacts reduction method of computer tomography in one embodiment;
Fig. 3 is the flow chart that final prior image obtains in one embodiment;
Fig. 4 is the flow chart of the metal artifacts reduction method of computer tomography in another embodiment;
Fig. 5 is the structural schematic diagram of the metal artifacts reduction system of computer tomography in one embodiment.
Specific embodiment
It is with reference to the accompanying drawings and embodiments, right in order to which the objects, technical solutions and advantages of the application are more clearly understood The application is further elaborated.It should be appreciated that specific embodiment described herein is only used to explain the application, not For limiting the application.
The metal artifacts reduction method of computer tomography provided by the present application can be applied to as shown in Figure 1 answer With in environment, Fig. 1 is the internal structure chart of computer equipment in one embodiment.Wherein, the computer equipment can with but it is unlimited Then various personal computers, laptop, smart phone, tablet computer and independent server either multiple servers The server cluster of composition.
In one embodiment, as shown in Fig. 2, Fig. 2 is the metal artifacts school of computer tomography in one embodiment The flow chart of correction method provides a kind of metal artifacts reduction method of computer tomography in the present embodiment, in this way Applied to being illustrated for the computer equipment in Fig. 1, comprising the following steps:
Step S210: computer tomography image to be corrected is obtained.
Computer tomography image to be corrected can be include metal information and metal artifacts information CT image.
Step S220: it treats and belongs to the regions of bone tissue intensity value ranges in correcting computer tomographic imaging image and divided It cuts, obtains bone segmentation area image.
Include bone tissue information in computer tomography image to be corrected, but has the ash of part metals puppet shadow information Angle value is exactly in bone tissue intensity value ranges, by including bone group in the obtained bone segmentation area image of segmentation Information and gray value are knitted in the metal artifacts information of bone tissue intensity value ranges.
Step S230: initial prior image is obtained according to computer tomography image to be corrected.
Initial prior image can be used for treating correcting computer tomographic imaging image and be corrected, should but will affect This is soft tissue area, such as fat and musculature area, other regions are seriously affected and be divided by metal artifacts, The accuracy of initial prior image is low.
Step S240: according to computer tomography image to be corrected, bone segmentation area image and initial priori figure As obtaining final prior image.
It should be influence that soft tissue area is subject to reduce, according to bone segmentation area image to initial priori Image continues further to correct, and obtains final prior image, improves the accuracy of final prior image.
Step S250: correcting computer tomography is obtained according to final prior image and computer tomography image to be corrected Image.
Correcting computer tomographic imaging image is treated according to the high final prior image of accuracy to be corrected, it is available More accurate correcting computer tomographic imaging image.
The metal artifacts reduction method of above-mentioned computer tomography includes bone tissue information in final prior image, The higher final prior image of accuracy is obtained, the accuracy of metal artifacts reduction can be improved.
In one embodiment, as shown in figure 3, Fig. 3 is the flow chart that final prior image obtains in one embodiment, root Final prior image is obtained according to computer tomography image to be corrected, bone segmentation area image and initial prior image Step, comprising the following steps:
Step S241: binary conversion treatment and filtering processing are successively carried out to bone segmentation area image, obtain bone tissue Handle image.
It can be partitioned into bone segmentation region by binary conversion treatment, using filtering processing, optimize obtained bone Tissue treatment image.
Step S242: according to bone tissue handle image by computer tomography image to be corrected and initial prior image into Row Weighted Fusion obtains final prior image.
Initial prior image is corrected by way of Weighted Fusion, obtains the higher final priori figure of accuracy Picture.
The metal artifacts reduction method of above-mentioned computer tomography, by successively successively being carried out to bone segmentation region Binary conversion treatment, filtering processing and Weighted Fusion, the available higher final prior image of accuracy.
In one embodiment, binary conversion treatment and filtering processing are successively carried out to bone segmentation area image, obtained Bone tissue handles the step of image, comprising the following steps:
Step S243: by the pixel of pixel in the region for belonging to bone tissue intensity value ranges in bone segmentation area image Value is set as 1, sets 0 for the pixel value of remaining pixel, obtains bone tissue binary image.
Step S244: according toBone tissue binary image is filtered, is obtained Image is handled to bone tissue.
Wherein,
W2(i, j) is the pixel that bone tissue handles image the i-th row jth column, and F (i, j) is the judgement of the pixel of the i-th row jth column Condition, W1(i+a, j+b) is the pixel of bone tissue binary image the i-th+a row jth+b column, and g () is the filtering of n × n size Matrix, n are odd number, and the numerical value of filtering matrix is made of 0 and 1,It is the of filtering matrix RowThe element of column, i and j are respectively positive integer, and a is the first increment, and b is the second increment.With Respectively positive integer.
For example, n value is 3, filtering matrix can be chosen are as follows:
The metal artifacts reduction method of above-mentioned computer tomography obtains bone tissue binary picture in binary conversion treatment Picture is filtered bone tissue binary image by filtering matrix, obtains bone tissue processing image, filtered bone tissue area Domain is obvious, in order to improve the accuracy of subsequent final prior image.
In one embodiment, image is handled for computer tomography image to be corrected and initial priori according to bone tissue The step of image is weighted fusion, obtains final prior image, comprising the following steps:
Step S245:
According to I_prior2 (i, j)=I_original (i, j) × W2(i,j)+I_prior1(i,j)×(1-W2(i,j)) It is weighted fusion, obtains final prior image.
Wherein, I_prior2 (i, j) be final prior image the i-th row jth column pixel, I_original (i, j) be to The pixel of correcting computer tomographic imaging image the i-th row jth column, W2(i, j) is the picture that bone tissue handles image the i-th row jth column Element, I_prior1 (i, j) are the pixel of initial prior image the i-th row jth column, and i and j are respectively positive integer.
The metal artifacts reduction method of above-mentioned computer tomography handles image according to bone tissue and obtains Weighted Fusion Weight, treats correcting computer tomographic imaging image and initial prior image is merged, and obtains including bone tissue information Final prior image improves the accuracy of final prior image.
In one embodiment, the region for belonging to bone tissue intensity value ranges in correcting computer tomographic imaging image is treated The step of being split, obtaining bone segmentation area image, comprising the following steps:
Step S221:
According to Obtain bone segmentation area image.
Wherein, I_bone_artifact (i, j) is the pixel of bone segmentation area image the i-th row jth column, I_ Original (i, j) is the pixel of computer tomography image the i-th row jth to be corrected column, T1For the judgement threshold of metal information Value, T2For the judgment threshold of bone tissue information, T2<T1, i and j are respectively positive integer.
The metal artifacts reduction method of above-mentioned computer tomography, according to the threshold value of the pixel value range of bone tissue information Range, it can be determined that area of bone tissue obtains the bone segmentation area image containing bone tissue information, in order to by bone tissue Packet is contained in final prior image.
In one embodiment, the step of initial prior image being obtained according to computer tomography image to be corrected, packet Include following steps:
Step S231: it treats metallic region in correcting computer tomographic imaging image and is split, obtain containing only metal The metal cut zone image of information.
In this step, the metal cut zone image for containing only metal information is obtained, the region of metal is split.
For example, according toObtain metal cut section Area image, wherein I_metal (i, j) is the pixel of metal cut zone image the i-th row jth column, and I_original (i, j) is The pixel of computer tomography image the i-th row jth column to be corrected, T1For the judgment threshold of metal information, i and j are positive respectively Integer.
Step S232: treating correcting computer tomographic imaging image respectively and the progress of metal cut zone image is preceding to throwing Shadow, and respectively obtain data for projection to be corrected and metal shadowing's data.
It treats correcting computer tomographic imaging image and metal cut zone image does following change process respectively:
I_original_norm=(I_original+Q)/Q,
I_metal_norm=(I_metal+Q)/Q,
Wherein, I_original is computer tomography image to be corrected, and I_original_norm is calculating to be corrected Machine tomographic imaging limit value image, I_metal are metal cut zone image, and I_metal_norm is metal cut zone limit value figure Picture, Q are preset limit value coefficient.The value of Q is greater than or equal to 1000, is less than or equal to 5000.
It treats correcting computer tomographic imaging limit value image and carries out forward projection, obtain data for projection and metal to be corrected and throw Shadow data;Forward projection is carried out to metal cut zone limit value image, obtains metal shadowing's data.When carrying out forward projection, adopt With identical Ray Tracing Algorithm and parallel beam or fladellum geometric projection mode, data for projection and gold to be corrected are respectively obtained Belong to data for projection.Data for projection to be corrected and metal shadowing's data are respectively two-dimensional matrix, and size is M × N, wherein M expression pair Image throw the angle sum of photograph, and N is indicated in each direction for parallel beam used in data for projection or fan beam Item number, the information after image are received by N number of detection member.
Step S233: determining the metallic region of data for projection to be corrected according to metal shadowing's data, according to projection to be corrected Data outside the metallic region both ends of data, the metallic region for treating corrected projection data carry out Interpolate estimation, obtain to be corrected Intermediate corrected projection data after the removal metal information of data for projection.
Nonzero value is metal information in metal shadowing's data, can judge that metal throwing is oriented in operation with simple non-zero Metallic region in shadow data, so that it is determined that the metallic region in data for projection to be corrected out, remembers under i-th of projection (i.e. projection square The i-th row of battle array) the beginning and end of metallic region be divided into i_start and i_end, wherein i is greater than 1, and is less than M.
Every a line (the i-th row) in corrected projection data is treated, i-th _ start-1 to the 1st element data are utilized The value set and i-th _ end+1 data value sets to n-th element, to i-th _ start element to i-th _ end element it Between data carry out interpolation processing, the intermediate corrected projection data after obtaining interpolation.It is linear that interpolation process method, which can choose, Interpolation, polynomial interopolation, the methods of B-spline interpolation.
Step S234: first is obtained according to intermediate corrected projection data and rebuilds computer tomography image, to the first weight It builds computer tomography image to be filtered, obtains initial prior image.
To real projection data reconstruction, the first reconstruction computer tomography image is obtained, which have and is protected The filtering algorithm of shield picture structure limbic function obtains initial prior image such as based on the Mean Filtering Algorithm of threshold value.Reconstruction side Method is preferably filtered back-projection method.
The metal artifacts reduction method of above-mentioned computer tomography can rapidly obtain initial prior image, improve The efficiency of metal artifacts reduction.
In one embodiment, correction is obtained according to final prior image and computer tomography image to be corrected to calculate The step of machine tomographic imaging image, comprising the following steps:
Step S251: forward projection is carried out to final prior image, prior image data for projection is obtained, according to prior image The metallic region that data for projection treats corrected projection data carries out interpolation correction, obtains corrected projection data.
When carrying out forward projection to final prior image, using with Ray Tracing Algorithm same in step S232 and parallel Beam or fladellum geometric projection mode, obtain prior image data for projection.It is thrown using data for projection to be corrected and prior image The pixel value of the corresponding pixel points of shadow data does division operation, obtains normalized data for projection.In being divided by, if denominator encounter for 0 the case where, enabling denominator value is with lesser positive number.Metal area in normalized data for projection is oriented using metal shadowing's data Domain, using the data in the data interpolating estimation metallic region of metallic region two sides, process and the Interpolation Process in step S233 It is identical, to obtain the data for projection after interpolation.Utilize the data for projection and prior image data for projection respective pixel after interpolation The pixel value of point does multiplication operation, and realization goes to normalize, and obtains corrected projection data.
Step S252: second is obtained according to corrected projection data and rebuilds computer tomography image, second is rebuild and is counted Calculation machine tomographic imaging image and metal cut zone image co-registration, obtain correcting computer tomographic imaging image.
Corrected projection data is rebuild, it is preferred to use filter back-projection reconstruction algorithm obtains I_correct2, and right I_correct2 carries out limit value and handles, and obtains the second reconstruction computer tomography image.
I_correct=int (I_correct2 × Q-Q)
Wherein, I_correct is the second reconstruction computer tomography image, and int () indicates to carry out data four houses Five enter to be rounded, and Q is preset limit value coefficient, and Q is identical as the value of Q in step S232.Later, by second rebuild computerized tomography at As image and metal cut zone image co-registration, i.e., second rebuild the pixel value of the corresponding pixel points of computer tomography image It is added, the correcting computer tomographic imaging image after obtaining correction of a final proof.
I_final (i, j)=I_correct (i, j)+I_metal (i, j)
Wherein, I_final (i, j) is the pixel of correcting computer tomographic imaging image the i-th row jth column, I_correct (i, j) is the second pixel for rebuilding computer tomography image the i-th row jth column, and I_metal (i, j) is metal cut zone The pixel of image the i-th row jth column, i and j are respectively positive integer.
The metal artifacts reduction method of above-mentioned computer tomography is thrown according to the prior image that final prior image obtains Shadow data carry out interpolation correction, obtain corrected projection data, according to corrected projection data can further with metal cut section Area image is merged, and the correcting computer tomographic imaging image after obtaining correction of a final proof improves the accurate of metal artifacts reduction Property.
In another embodiment, as shown in figure 4, Fig. 4 is the metal puppet of computer tomography in another embodiment The flow chart of shadow bearing calibration, provides a kind of metal artifacts reduction method of computer tomography in the present embodiment, including with Lower step:
Import a width matrix size be 512 × 512 I_original, I_original be computerized tomography to be corrected at As image, computer tomography image to be corrected is the computer tomography image containing metal and its artifact.Wherein, it counts The minimum value of calculation machine tomographic imaging image pixel value is -1000, indicates air;Maximum value reaches+3500, indicates the maximum of metal Computer tomography pixel value.
T is obtained according to CT image grey level histogram or experience1, T1For the judgment threshold of metal information, T1=+3000.It is logical It crosses following formula and is partitioned into metal information from I_original, obtain I_metal, I_metal is metal cut zone image:
Wherein, I_metal (i, j) is the pixel of metal cut zone image the i-th row jth column, and I_original (i, j) is The pixel of computer tomography image the i-th row jth column to be corrected, T1For the judgment threshold of metal information, i and j are positive respectively Integer.
T is obtained according to CT image grey level histogram or experience2, T2For the judgment threshold of bone tissue information, T2=+800. Bone tissue information and metal artifacts identical with bone tissue intensity value ranges are partitioned into from I_original by following formula Information obtains I_bone_artifact, and I_bone_artifact is bone segmentation area image:
Wherein, I_bone_artifact (i, j) is the pixel of bone segmentation area image the i-th row jth column, I_ Original (i, j) is the pixel of computer tomography image the i-th row jth to be corrected column, T1For the judgement threshold of metal information Value, T2For the judgment threshold of bone tissue information, T2<T1, i and j are respectively positive integer.
It is excessive that there is a situation where data values in a series of subsequent processing in order to prevent, does to I_original and I_metal Following change process:
I_original_norm=(I_original+1000)/1000
I_metal_norm=(I_metal+1000)/1000
I_original_norm and I_metal_norm is respectively computer tomography limit value image and metal to be corrected Cut zone limit value image.Then I_original_norm and I_metal_norm minimum value is 0, maximum value 4.5.
When carrying out forward projection to I_original_norm and I_metal_norm, using identical Ray Tracing Algorithm With parallel beam geometry projection pattern, respectively obtain p_original and p_metal, p_original and p_metal be respectively to Corrected projection data and metal shadowing's data, above-mentioned data for projection are two-dimensional matrix, and size is 720 × 724, that is, surround image one The data for projection under 720 directions is uniformly acquired in all ranges, the data for projection number in each direction is 724.
Nonzero value is metal information in p_metal, judges that data for projection p_metal is oriented in operation with simple non-zero Middle metallic region, so that it is determined that the metallic region in p_original out, remembers (i.e. the i-th row of projection matrix) under i-th of projection The beginning and end of metallic region is divided into i_start and i_end, and wherein i is greater than 1, and less than 720.
To every a line (the i-th row) in p_original, i-th _ start-1 to the 1st element data value collection are utilized The data value set with i-th _ end+1 to the 724th element is closed, to i-th _ start element between i-th _ end element Data carry out interpolation processing, the p_line after obtaining interpolation, p_line be real projection data.Interpolation process method is selected as Linear interpolation.
Back projection method is filtered to p_line to rebuild, obtains I_correct1, and I_correct1 is the first reconstruction meter Calculation machine tomographic imaging image carries out I_correct1 to obtain I_ with the filtering algorithm of protection picture structure limbic function Prior1, I_prior1 are initial prior image, and in the present embodiment, filtering algorithm formula be can choose are as follows:
Wherein, I_prior1 (i, j) is the pixel of initial prior image the i-th row jth column, and I_correct1 (i', j') is The pixel of first reconstruction the i-th ' row of computer tomography image jth ' column, w is matrix, and v value is that 3, S value is 0.15, sum (w) for matrix w sum operation, i, j, i' and j ' it is respectively positive integer.
To the I_bone_artifact containing bone tissue information and metal artifacts identical with bone tissue intensity value ranges into The process of row binary conversion treatment are as follows: enable containing in bone tissue information and metal artifacts identical with bone tissue intensity value ranges region The pixel value of all pixels point be 1, the pixel value of all pixels point outside region is 0.Image after binaryzation is denoted as W1
To W1The process being filtered are as follows:
Wherein,
Wherein, W2(i, j) is the pixel that bone tissue handles image the i-th row jth column, and F (i, j) is the pixel of the i-th row jth column Rule of judgment, W1(i+a, j+b) is the pixel of bone tissue binary image the i-th+a row jth+b column, and g () is n × n size Filtering matrix, n is odd number, and the numerical value of filtering matrix is made of 0 and 1,It is the of filtering matrixRowThe element of column, a, b, i and j are respectively positive integer.N value is 3, g () selection in the present embodiment Are as follows:
Utilize W2Instruct the process of the Weighted Fusion of I_original and I_prior1 are as follows:
I_prior2 (i, j)=I_original (i, j) × W2(i,j)+I_prior1(i,j)×(1-W2(i,j))
Wherein, I_prior2 (i, j) be final prior image the i-th row jth column pixel, I_original (i, j) be to The pixel of correcting computer tomographic imaging image the i-th row jth column, W2(i, j) is the picture that bone tissue handles image the i-th row jth column Element, I_prior1 (i, j) are the pixel of initial prior image the i-th row jth column, and i and j are respectively positive integer.
When to prior image I_prior2 row forward projection, using with I_original_norm and I_metal_norm into Same Ray Tracing Algorithm and parallel beam geometry projection pattern when row forward projection, obtain p_prior, p_prior is priori Image projection data.
Division operation is done using the pixel value of the corresponding pixel points of p_original and p_prior, obtains normalized throwing Shadow data, are denoted as p_norm1.In being divided by, when denominator encounters the case where being 0, enabling denominator value is with lesser positive number, the present embodiment In be set as 0.0001.
Metallic region in p_norm1 is oriented using p_metal, estimates metal using the data interpolating of metallic region two sides Data in region, process is identical as above-mentioned interpolation method process, to obtain p_norm2, p_norm2 is the projection after interpolation Data.
Multiplication operation is done using the pixel value of p_norm2 and p_prior corresponding pixel points, realization goes to normalize, and obtains p_ Correct2, p_correct2 are corrected projection data.
Backprojection reconstruction is filtered to p_correct2, obtains I_correct2, and I_correct2 is carried out as follows Processing:
I_correct=int (I_correct2 × 1000-1000)
Wherein, I_correct is the second reconstruction computer tomography image, and int () indicates to carry out data four houses Five enter to be rounded.
I_correct is merged with I_metal, and the I_final after obtaining correction of a final proof, I_final are disconnected for correcting computer Layer image.
I_final (i, j)=I_correct (i, j)+I_metal (i, j)
Wherein, I_final (i, j) is the pixel of correcting computer tomographic imaging image the i-th row jth column, I_correct (i, j) is the second pixel for rebuilding computer tomography image the i-th row jth column, and I_metal (i, j) is metal cut zone The pixel of image the i-th row jth column, i and j are respectively positive integer.
The metal artifacts reduction method of above-mentioned computer tomography constructs good final prior image, improves correction As a result;And independent of hardware parameter, applicability and practical.
It should be understood that although each step in the flow chart of Fig. 2 to 4 is successively shown according to the instruction of arrow, It is these steps is not that the inevitable sequence according to arrow instruction successively executes.Unless expressly stating otherwise herein, these steps There is no stringent sequences to limit for rapid execution, these steps can execute in other order.Moreover, in Fig. 2 to 4 at least A part of step may include that perhaps these sub-steps of multiple stages or stage are not necessarily in same a period of time to multiple sub-steps Quarter executes completion, but can execute at different times, the execution in these sub-steps or stage be sequentially also not necessarily according to Secondary progress, but in turn or can replace at least part of the sub-step or stage of other steps or other steps Ground executes.
In one embodiment, as shown in figure 5, Fig. 5 is the metal artifacts school of computer tomography in one embodiment The structural schematic diagram of positive system provides a kind of metal artifacts reduction system of computer tomography, including image to be corrected Obtain module 310, bone segmentation area image obtains module 320, initial prior image obtains module 330, final priori figure As obtaining module 340 and correction image collection module 350, in which:
Image collection module 310 to be corrected, for obtaining computer tomography image to be corrected.
Computer tomography image to be corrected can be include metal information and metal artifacts information CT image.
Bone segmentation area image obtains module 320, belongs to bone for treating in correcting computer tomographic imaging image The region of tissue intensity value ranges is split, and obtains bone segmentation area image.
Include bone tissue information in computer tomography image to be corrected, but has the ash of part metals puppet shadow information Angle value is exactly in bone tissue intensity value ranges, by including bone group in the obtained bone segmentation area image of segmentation Information and gray value are knitted in the metal artifacts information of bone tissue intensity value ranges.Initial prior image obtains module 330, is used for Initial prior image is obtained according to computer tomography image to be corrected.
Initial prior image can be used for treating correcting computer tomographic imaging image and be corrected, should but will affect This is soft tissue area, such as bone and musculature area, other regions are seriously affected and be divided by metal artifacts, The accuracy of initial prior image is low.
Final prior image obtains module 340, for according to computer tomography image to be corrected, bone segmentation area Area image and initial prior image obtain final prior image.
It should be influence that soft tissue area is subject to reduce, according to bone segmentation area image to initial priori Image continues further to correct, and obtains final prior image, improves the accuracy of final prior image.
Image collection module 350 is corrected, for obtaining according to final prior image and computer tomography image to be corrected Take correcting computer tomographic imaging image.
Correcting computer tomographic imaging image is treated according to the high final prior image of accuracy to be corrected, it is available More accurate correcting computer tomographic imaging image.
The metal artifacts reduction system of above-mentioned computer tomography includes bone tissue information in final prior image, The higher final prior image of accuracy is obtained, the accuracy of metal artifacts reduction can be improved.
The specific restriction of metal artifacts reduction system about computer tomography may refer to above for calculating The restriction of the metal artifacts reduction method of machine tomographic imaging, details are not described herein.The metal artifacts of above-mentioned computer tomography Modules in correction system can be realized fully or partially through software, hardware and combinations thereof.Above-mentioned each module can be hard Part form is embedded in or independently of in the processor in computer equipment, can also be stored in computer equipment in a software form Memory in, execute the corresponding operation of above modules in order to which processor calls.
In one embodiment, a kind of computer equipment is provided, which can be server, internal junction Composition can as shown in FIG. 1, FIG. 1 is the internal structure charts of computer equipment in one embodiment.The computer equipment includes logical Cross processor, memory and the network interface of system bus connection.Wherein, the processor of the computer equipment is for providing calculating And control ability.The memory of the computer equipment includes non-volatile memory medium, built-in storage.The non-volatile memories are situated between Matter is stored with operating system and computer program.The built-in storage is operating system and computer in non-volatile memory medium The operation of program provides environment.The network interface of the computer equipment is used to communicate with external terminal by network connection.It should A kind of metal artifacts reduction method of computer tomography is realized when computer program is executed by processor.
It will be understood by those skilled in the art that structure shown in Fig. 1, only part relevant to application scheme is tied The block diagram of structure does not constitute the restriction for the computer equipment being applied thereon to application scheme, specific computer equipment It may include perhaps combining certain components or with different component layouts than more or fewer components as shown in the figure.
In one embodiment, a kind of computer equipment is provided, including memory, processor and storage are on a memory And the computer program that can be run on a processor, processor perform the steps of when executing computer program
Obtain computer tomography image to be corrected;
Initial prior image is obtained according to computer tomography image to be corrected;
It is obtained according to computer tomography image to be corrected, bone segmentation area image and initial prior image final Prior image;
Correcting computer tomographic imaging image is obtained according to final prior image and computer tomography image to be corrected.
In one embodiment, it is also performed the steps of when processor executes computer program
Binary conversion treatment and filtering processing are successively carried out to bone segmentation area image, obtain bone tissue processing image; Image is handled according to bone tissue, computer tomography image to be corrected and initial prior image are weighted fusion, obtain most Whole prior image.
In one embodiment, it is also performed the steps of when processor executes computer program
It sets the pixel value of pixel in the region for belonging to bone tissue intensity value ranges in bone segmentation area image to 1,0 is set by the pixel value of remaining pixel, obtains bone tissue binary image;According to Bone tissue binary image is filtered, bone tissue processing image is obtained,
Wherein,
W2(i, j) is the pixel that bone tissue handles image the i-th row jth column, and F (i, j) is sentencing for the pixel of the i-th row jth column Broken strip part, W1(i+a, j+b) is the pixel of bone tissue binary image the i-th+a row jth+b column, and g () is the filter of n × n size Wave matrix, n are odd number, and the numerical value of filtering matrix is made of 0 and 1,It is the of filtering matrix RowThe element of column, i and j are respectively positive integer, and a is the first increment, and b is the second increment.
In one embodiment, it is also performed the steps of when processor executes computer program
According to I_prior2 (i, j)=I_original (i, j) × W2(i,j)+I_prior1(i,j)×(1-W2(i,j)) It is weighted fusion, obtains final prior image,
Wherein, I_prior2 (i, j) be final prior image the i-th row jth column pixel, I_original (i, j) be to The pixel of correcting computer tomographic imaging image the i-th row jth column, W2(i, j) is the picture that bone tissue handles image the i-th row jth column Element, I_prior1 (i, j) are the pixel of initial prior image the i-th row jth column, and i and j are respectively positive integer.
In one embodiment, it is also performed the steps of when processor executes computer program
According to Bone segmentation area image is obtained,
Wherein, I_bone_artifact (i, j) is the pixel of bone segmentation area image the i-th row jth column, I_ Original (i, j) is the pixel of computer tomography image the i-th row jth to be corrected column, T1For the judgement threshold of metal information Value, T2For the judgment threshold of bone tissue information, T2<T1, i and j are respectively positive integer.
In one embodiment, it is also performed the steps of when processor executes computer program
It treats metallic region in correcting computer tomographic imaging image to be split, obtains the metal for containing only metal information Cut zone image;Correcting computer tomographic imaging image is treated respectively and metal cut zone image carries out forward projection, and Respectively obtain data for projection to be corrected and metal shadowing's data;The metal of data for projection to be corrected is determined according to metal shadowing's data Region, according to the data outside the metallic region both ends of data for projection to be corrected, the metallic region for treating corrected projection data is carried out Interpolate estimation, the intermediate corrected projection data after obtaining the removal metal information of data for projection to be corrected;It is thrown according to centre correction Shadow data acquisition first rebuilds computer tomography image, is filtered place to the first reconstruction computer tomography image Reason, obtains initial prior image.
In one embodiment, it is also performed the steps of when processor executes computer program
Forward projection is carried out to final prior image, prior image data for projection is obtained, according to prior image data for projection The metallic region for treating corrected projection data carries out interpolation correction, obtains corrected projection data;It is obtained according to corrected projection data Second rebuilds computer tomography image, and the second reconstruction computer tomography image is melted with metal cut zone image It closes, obtains correcting computer tomographic imaging image.
In one embodiment, a kind of computer readable storage medium is provided, computer program is stored thereon with, is calculated Machine program performs the steps of when being executed by processor
Obtain computer tomography image to be corrected;
Initial prior image is obtained according to computer tomography image to be corrected;
It is obtained according to computer tomography image to be corrected, bone segmentation area image and initial prior image final Prior image;
Correcting computer tomographic imaging image is obtained according to final prior image and computer tomography image to be corrected.
In one embodiment, it is also performed the steps of when computer program is executed by processor
Binary conversion treatment and filtering processing are successively carried out to bone segmentation area image, obtain bone tissue processing image; Image is handled according to bone tissue, computer tomography image to be corrected and initial prior image are weighted fusion, obtain most Whole prior image.
In one embodiment, it is also performed the steps of when computer program is executed by processor
It sets the pixel value of pixel in the region for belonging to bone tissue intensity value ranges in bone segmentation area image to 1,0 is set by the pixel value of remaining pixel, obtains bone tissue binary image;According to Bone tissue binary image is filtered, bone tissue processing image is obtained,
Wherein,
W2(i, j) is the pixel that bone tissue handles image the i-th row jth column, and F (i, j) is sentencing for the pixel of the i-th row jth column Broken strip part, W1(i+a, j+b) is the pixel of bone tissue binary image the i-th+a row jth+b column, and g () is the filter of n × n size Wave matrix, n are odd number, and the numerical value of filtering matrix is made of 0 and 1,It is the of filtering matrix RowThe element of column, i and j are respectively positive integer, and a is the first increment, and b is the second increment.
In one embodiment, it is also performed the steps of when computer program is executed by processor
According to I_prior2 (i, j)=I_original (i, j) × W2(i,j)+I_prior1(i,j)×(1-W2(i,j)) It is weighted fusion, obtains final prior image,
Wherein, I_prior2 (i, j) be final prior image the i-th row jth column pixel, I_original (i, j) be to The pixel of correcting computer tomographic imaging image the i-th row jth column, W2(i, j) is the picture that bone tissue handles image the i-th row jth column Element, I_prior1 (i, j) are the pixel of initial prior image the i-th row jth column, and i and j are respectively positive integer.
In one embodiment, it is also performed the steps of when computer program is executed by processor
According to Bone segmentation area image is obtained,
Wherein, I_bone_artifact (i, j) is the pixel of bone segmentation area image the i-th row jth column, I_ Original (i, j) is the pixel of computer tomography image the i-th row jth to be corrected column, T1For the judgement threshold of metal information Value, T2For the judgment threshold of bone tissue information, T2<T1, i and j are respectively positive integer.
In one embodiment, it is also performed the steps of when computer program is executed by processor
It treats metallic region in correcting computer tomographic imaging image to be split, obtains the metal for containing only metal information Cut zone image;Correcting computer tomographic imaging image is treated respectively and metal cut zone image carries out forward projection, and Respectively obtain data for projection to be corrected and metal shadowing's data;The metal of data for projection to be corrected is determined according to metal shadowing's data Region, according to the data outside the metallic region both ends of data for projection to be corrected, the metallic region for treating corrected projection data is carried out Interpolate estimation, the intermediate corrected projection data after obtaining the removal metal information of data for projection to be corrected;It is thrown according to centre correction Shadow data acquisition first rebuilds computer tomography image, is filtered place to the first reconstruction computer tomography image Reason, obtains initial prior image.
In one embodiment, it is also performed the steps of when computer program is executed by processor
Forward projection is carried out to final prior image, prior image data for projection is obtained, according to prior image data for projection The metallic region for treating corrected projection data carries out interpolation correction, obtains corrected projection data;It is obtained according to corrected projection data Second rebuilds computer tomography image, and the second reconstruction computer tomography image is melted with metal cut zone image It closes, obtains correcting computer tomographic imaging image.
Those of ordinary skill in the art will appreciate that realizing all or part of the process in above-described embodiment method, being can be with Relevant hardware is instructed to complete by computer program, the computer program can be stored in a non-volatile computer In read/write memory medium, the computer program is when being executed, it may include such as the process of the embodiment of above-mentioned each method.Wherein, To any reference of memory, storage, database or other media used in each embodiment provided herein, Including non-volatile and/or volatile memory.Nonvolatile memory may include read-only memory (ROM), programming ROM (PROM), electrically programmable ROM (EPROM), electrically erasable ROM (EEPROM) or flash memory.Volatile memory may include Random access memory (RAM) or external cache.By way of illustration and not limitation, RAM is available in many forms, Such as static state RAM (SRAM), dynamic ram (DRAM), synchronous dram (SDRAM), double data rate sdram (DDRSDRAM), enhancing Type SDRAM (ESDRAM), synchronization link (Synchlink) DRAM (SLDRAM), memory bus (Rambus) direct RAM (RDRAM), direct memory bus dynamic ram (DRDRAM) and memory bus dynamic ram (RDRAM) etc..
Each technical characteristic of above embodiments can be combined arbitrarily, for simplicity of description, not to above-described embodiment In each technical characteristic it is all possible combination be all described, as long as however, the combination of these technical characteristics be not present lance Shield all should be considered as described in this specification.
The several embodiments of the application above described embodiment only expresses, the description thereof is more specific and detailed, but simultaneously It cannot therefore be construed as limiting the scope of the patent.It should be pointed out that coming for those of ordinary skill in the art It says, without departing from the concept of this application, various modifications and improvements can be made, these belong to the protection of the application Range.Therefore, the scope of protection shall be subject to the appended claims for the application patent.

Claims (10)

1. a kind of metal artifacts reduction method of computer tomography, which comprises the following steps:
Obtain computer tomography image to be corrected;
The region for belonging to bone tissue intensity value ranges in the computer tomography image to be corrected is split, bone is obtained Tissue segmentation area image;
Initial prior image is obtained according to the computer tomography image to be corrected;
According to computer tomography image, the bone segmentation area image and the initial prior image to be corrected Obtain final prior image;
Correcting computer tomographic imaging is obtained according to the final prior image and the computer tomography image to be corrected Image.
2. the metal artifacts reduction method of computer tomography according to claim 1, which is characterized in that the basis The computer tomography image to be corrected, the bone segmentation area image and the initial prior image obtain final The step of prior image, comprising the following steps:
Binary conversion treatment and filtering processing are successively carried out to the bone segmentation area image, obtain bone tissue processing image;
According to the bone tissue handle image by the computer tomography image to be corrected and the initial prior image into Row Weighted Fusion obtains final prior image.
3. the metal artifacts reduction method of computer tomography according to claim 2, which is characterized in that described to institute The step of stating bone segmentation area image and successively carry out binary conversion treatment and filtering processing, obtaining bone tissue processing image, packet Include following steps:
It sets the pixel value of pixel in the region for belonging to bone tissue intensity value ranges in the bone segmentation area image to 1,0 is set by the pixel value of remaining pixel, obtains bone tissue binary image;
According toThe bone tissue binary image is filtered, the bone group is obtained Processing image is knitted,
Wherein,
W2(i, j) is the pixel that the bone tissue handles image the i-th row jth column, and F (i, j) is the judgement of the pixel of the i-th row jth column Condition, W1(i+a, j+b) is the pixel of bone tissue binary image the i-th+a row jth+b column, and g () is n × n size Filtering matrix, n are odd number, and the numerical value of the filtering matrix is made of 0 and 1,For the filtering matrix ?RowThe element of column, i and j are respectively positive integer, and a is the first increment, and b is the second increment.
4. the metal artifacts reduction method of computer tomography according to claim 2, which is characterized in that the basis The computer tomography image to be corrected and the initial prior image are weighted and are melted by the bone tissue processing image The step of closing, obtaining final prior image, comprising the following steps:
According to I_prior2 (i, j)=I_original (i, j) × W2(i,j)+I_prior1(i,j)×(1-W2(i, j)) it carries out Weighted Fusion obtains the final prior image,
Wherein, I_prior2 (i, j) is the pixel of final prior image the i-th row jth column, and I_original (i, j) is institute State the pixel of computer tomography image the i-th row jth column to be corrected, W2(i, j) is that the bone tissue handles the i-th row of image the The pixel of j column, I_prior1 (i, j) are the pixel of initial prior image the i-th row jth column, and i and j are respectively positive integer.
5. the metal artifacts reduction method of computer tomography according to claim 1, which is characterized in that described to institute It states and belongs to the regions of bone tissue intensity value ranges in computer tomography image to be corrected and be split, obtain bone segmentation The step of area image, comprising the following steps:
According to The bone segmentation area image is obtained,
Wherein, I_bone_artifact (i, j) is the pixel of bone segmentation area image the i-th row jth column, I_ Original (i, j) is the pixel of computer tomography image the i-th row jth column to be corrected, T1For sentencing for metal information Disconnected threshold value, T2For the judgment threshold of bone tissue information, T2<T1, i and j are respectively positive integer.
6. the metal artifacts reduction method of computer tomography according to claim 1, which is characterized in that the basis The step of computer tomography image to be corrected obtains initial prior image, comprising the following steps:
Metallic region in the computer tomography image to be corrected is split, the metal for containing only metal information is obtained Cut zone image;
Forward projection is carried out to the computer tomography image to be corrected and the metal cut zone image respectively, and is divided Data for projection to be corrected and metal shadowing's data are not obtained;
The metallic region that the data for projection to be corrected is determined according to metal shadowing's data, according to the projection number to be corrected According to metallic region both ends outside data, Interpolate estimation is carried out to the metallic region of the data for projection to be corrected, is obtained described Intermediate corrected projection data after the removal metal information of data for projection to be corrected;
First is obtained according to the intermediate corrected projection data and rebuilds computer tomography image, is rebuild and is calculated to described first Machine tomographic imaging image is filtered, and obtains initial prior image.
7. the metal artifacts reduction method of computer tomography according to claim 1, which is characterized in that the basis The final prior image and the computer tomography image to be corrected obtain the step of correcting computer tomographic imaging image Suddenly, comprising the following steps:
Forward projection is carried out to the final prior image, prior image data for projection is obtained, is projected according to the prior image Data carry out interpolation correction to the metallic region of the data for projection to be corrected, obtain corrected projection data;
Second is obtained according to the corrected projection data and rebuilds computer tomography image, and the second reconstruction computer is broken Layer image and the metal cut zone image co-registration, obtain the correcting computer tomographic imaging image.
8. a kind of metal artifacts reduction system of computer tomography, which is characterized in that the system comprises:
Image collection module to be corrected, for obtaining computer tomography image to be corrected;
Bone segmentation area image obtains module, for belonging to bone tissue in the computer tomography image to be corrected The region of intensity value ranges is split, and obtains bone segmentation area image;
Initial prior image obtains module, for obtaining initial priori figure according to the computer tomography image to be corrected Picture;
Final prior image obtains module, for according to the computer tomography image to be corrected, the bone segmentation Area image and the initial prior image obtain final prior image;
Image collection module is corrected, for obtaining according to the final prior image and the computer tomography image to be corrected Take correcting computer tomographic imaging image.
9. a kind of computer equipment including memory, processor and stores the meter that can be run on a memory and on a processor Calculation machine program, which is characterized in that the processor realizes any one of claims 1 to 7 institute when executing the computer program The step of metal artifacts reduction method for the computer tomography stated.
10. a kind of computer readable storage medium, is stored thereon with computer program, which is characterized in that the computer program The metal artifacts reduction method of computer tomography described in any one of claims 1 to 7 is realized when being executed by processor The step of.
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