CN109107045B - Individualized non-uniform rotation irradiation method, system and terminal - Google Patents
Individualized non-uniform rotation irradiation method, system and terminal Download PDFInfo
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Abstract
The invention discloses an individual non-uniform rotation irradiation method, a system and a terminal, wherein the method comprises the following steps: controlling the rotation of a rotary motor by using the constructed non-uniform rotation control code and the preset number of rotation turns so as to enable the electronic wire to perform non-uniform rotation irradiation in the transverse circumferential direction of the human body; the electron beam is generated by the linear accelerator according to a preset hop count. The system includes a control unit. The terminal comprises a memory for storing a program and a processor for loading a program to perform the illumination method. By using the invention, the individual non-uniform electronic wire rotary irradiation can be carried out on the patient through constructing the non-uniform rotary control codes corresponding to different patients, so that the bodies of different patients can be subjected to very uniform dose, and reliable dose data basis can be provided for the later dose supplementing operation. The invention can be widely applied to the technical field of medical electronics.
Description
Technical Field
The invention relates to the technical field of medical electronics, in particular to an individual non-uniform-speed rotating irradiation method, system and terminal for electron beam whole body radiotherapy.
Background
Electron beam systemic radiotherapy (TSEI) is mainly used for treating systemic skin cancer of mycosis fungoides. Currently, two methods are mainly adopted for implementing the TSEI technology: fixed angle irradiation and uniform rotation irradiation. For the fixed-angle irradiation mode, the treatment period is long, the working efficiency is low, the time is consumed for positioning, the repeatability is poor, and more overlapped high-dose areas are easy to appear on a patient due to the positioning angle error, so that the curative effect is influenced; however, for the uniform-speed rotation irradiation mode, although there is no problem of the positioning angle, the working efficiency is greatly improved, and the treatment period is shortened by half, because the human body is not a standard cylinder, but is only similar to an elliptic cylinder, after the uniform-speed rotation irradiation, different irradiated doses can be obtained on different parts in the transverse direction of the patient body, that is, the whole body skin can not obtain uniform dose, which affects the curative effect of radiotherapy. Clinical studies show that the more uniform the dosage of the whole body skin, the better the curative effect and the fewer side effects of radiotherapy of patients. However, the body of different patients has great individual difference, and is fat or thin, the body curved surfaces of men and women are different, and even if a specific patient is irradiated by uniform rotation at a certain rotation speed, the patient cannot obtain uniform dosage. In addition, patients with systemic skin cancer have large subcutaneous lymph nodes, after the radiation of the systemic skin is completed, the dosage of the lymph nodes needs to be supplemented with the dosage in the later process, but the current measurement technology can only obtain the dosage of the lymph nodes corresponding to the surface of the skin, and the real dosage in the lymph nodes cannot be known, so that certain blindness exists in the dosage supplementing in the later process; also, current measurement techniques also fail to accurately obtain their exposure dose for vital organs in the patient, such as the lungs, heart, spinal cord, thyroid, crystal, etc., and thus fail to make a prognostic assessment.
Disclosure of Invention
In order to solve the above technical problems, an object of the present invention is to provide an individual non-uniform rotational irradiation method, system and terminal for electron beam whole body radiotherapy, which can achieve higher uniformity of dose obtained on the body of a patient.
The first technical scheme adopted by the invention is as follows: an individualized non-uniform speed rotation irradiation method comprises the following steps:
controlling the rotation of a rotary motor by using the constructed non-uniform rotation control code and the preset number of rotation turns so as to enable the electronic wire to perform non-uniform rotation irradiation in the transverse circumferential direction of the human body; the electron beam is generated by the linear accelerator according to a preset hop count.
Further, the non-uniform rotation control code is a control code constructed by the following code construction steps:
controlling the rotation of the rotary motor to obtain the irradiation dose received by the plurality of dose detectors under the constant-speed rotation of different rotating speeds at each equal-part angle; the equal-part angle is obtained by dividing equal parts of angles by taking the human body model as a center in the transverse circumferential direction of the human body model, the human body model is a 3D printed human body model with a plurality of dose monitoring holes in the body part, and the dose detectors are respectively arranged in the dose monitoring holes in a one-to-one correspondence manner;
calculating the optimal rotating speed of each equal angle corresponding to the target irradiation dose by using the irradiation doses received by the plurality of dose detectors under the constant-speed rotation of each equal angle at different rotating speeds;
and generating corresponding non-uniform rotation control codes according to the calculated optimal rotation speed of each equal angle.
Further, the step of calculating the optimal rotation speed of each equal angle corresponding to the target irradiation dose by using the irradiation doses received by the plurality of dose detectors under the uniform rotation of each equal angle at different rotation speeds specifically includes:
calculating the total irradiation dose received by each dose detector under the constant rotation at different rotation speeds according to the irradiation dose received by each dose detector under the constant rotation at different rotation speeds at each equal division angle;
obtaining the absolute difference between the total irradiation dose and the target irradiation dose received by each dose detector under constant-speed rotation at different rotating speeds according to the required target irradiation dose;
and finding out the minimum value of the sum of absolute differences between the total irradiation dose and the target irradiation dose received by the plurality of dose detectors, thereby obtaining the optimal rotating speed of the target irradiation dose corresponding to each equal-divided angle.
Further, the step of obtaining the optimal rotation speed of the target irradiation dose corresponding to each equal division angle by finding the minimum value of the sum of the absolute differences between the total irradiation dose and the target irradiation dose received by the plurality of dose detectors is specifically as follows:
and finding out the minimum value of the sum of absolute differences between the total irradiation dose and the target irradiation dose received by the plurality of dose detectors by adopting a simulated annealing algorithm, thereby obtaining the optimal rotating speed of the target irradiation dose corresponding to each equal-part angle.
Further, the 3D printing human body model is a 3D printing human body model constructed by the following model construction steps:
acquiring a CT scanning image of a human body;
constructing a corresponding 3D human body virtual model according to the CT scanning image of the human body; the position of a dose monitoring hole is marked on the 3D human body virtual model;
and printing the corresponding 3D printing human body model according to the STL file of the 3D human body virtual model.
Further, the step of constructing a corresponding 3D human body virtual model according to the CT scan image of the human body specifically includes:
and constructing a corresponding 3D human body virtual model according to the CT scanning image of the human body by using three-dimensional reconstruction software, and generating an STL file of the 3D human body virtual model.
The second technical scheme adopted by the invention is as follows: an individualized non-uniform rotational illumination system, comprising:
the control unit is used for controlling the rotation of the rotary motor by utilizing the constructed non-uniform rotation control code and the preset number of rotation turns so as to enable the electronic wire to perform non-uniform rotation irradiation in the transverse circumferential direction of the human body; the electron beam is generated by the linear accelerator according to a preset hop count.
Further, the method further comprises a first constructing unit for constructing the non-uniform rotation control code, wherein the first constructing unit comprises:
the first acquisition module is used for controlling the rotation of the rotary motor so as to acquire the irradiation dose received by the plurality of dose detectors under the uniform rotation of different rotating speeds at each equal-dividing angle; the equal-part angle is obtained by dividing equal parts of angles by taking the human body model as a center in the transverse circumferential direction of the human body model, the human body model is a 3D printed human body model with a plurality of dose monitoring holes in the body part, and the dose detectors are respectively arranged in the dose monitoring holes in a one-to-one correspondence manner;
the calculation module is used for calculating the optimal rotating speed of each equal angle corresponding to the target irradiation dose by utilizing the irradiation doses received by the plurality of dose detectors under the constant-speed rotation of each equal angle at different rotating speeds;
and the generating module is used for generating corresponding non-uniform rotation control codes according to the calculated optimal rotating speed of each equal part angle.
Further, a second construction unit for constructing the 3D printed manikin is included, the second construction unit comprising:
the second acquisition module is used for acquiring a CT scanning image of a human body;
the building module is used for building a corresponding 3D human body virtual model according to the CT scanning image of the human body; the position of a dose monitoring hole is marked on the 3D human body virtual model;
and the printing module is used for printing the corresponding 3D printing human body model according to the STL file of the 3D human body virtual model.
The third technical scheme adopted by the invention is as follows: a terminal, comprising:
at least one processor;
at least one memory for storing at least one program;
when executed by the at least one processor, cause the at least one processor to implement one of the individualized non-uniform rotational irradiation methods described above.
The method, the system and the terminal have the advantages that: the invention controls the rotation of the rotary motor by utilizing the constructed non-uniform rotation control code and the preset number of rotation turns so as to enable the electronic wire generated by the linear accelerator according to the preset hop number to carry out non-uniform rotation irradiation in the transverse circumferential direction of the human body, thus carrying out corresponding individualized non-uniform electronic wire rotation irradiation on patients by constructing the non-uniform rotation control code corresponding to different patients, enabling different patients to be subjected to very uniform dosage on the bodies, and having high operation flexibility and application compatibility.
In addition, due to the adoption of the code construction step, the irradiation dose of some interested organs (such as lung and lymph node) on the patient can be accurately acquired, so that a reliable dose data basis can be provided for the subsequent dose supplementing operation, and the dose supplementing precision is improved.
Drawings
FIG. 1 is a flow chart illustrating the steps of an embodiment of a method for individualized non-uniform rotational illumination according to the present invention;
FIG. 2 is a schematic layout diagram of a plurality of dosage monitoring holes on a 3D printed human body model;
FIG. 3 is a schematic illustration of a 3D printed mannequin on a rotating disk;
FIG. 4 is a schematic view of the lateral circumference of the human body;
FIG. 5 is a schematic view of the division of angular equal parts in the lateral circumferential direction of the human body;
fig. 6 is a schematic structural diagram of a terminal according to the present invention.
Detailed Description
In order to obtain more uniform dose on a patient in electron beam whole body radiotherapy and enhance the curative effect of radiotherapy, the invention adopts a 3D printing technology to construct a three-dimensional virtual human body model of the patient, prints out a 3D printing human body model, measures whole body subcutaneous dose and doses of some interested organs in the 3D printing human body model by using a multi-channel dose measuring device (namely a plurality of dose detectors), and reversely finds out the optimal rotating speed of different body parts (namely different equal parts of angles) of the patient under the irradiation of electron beams by a mathematical algorithm, thereby generating and obtaining a non-uniform rotating motor control code corresponding to the patient; the code is then preferably executed by a control computer to control the rotation of the rotary motor so that a more uniform dose is obtained on the patient after irradiation by the electron beam. The invention is described in further detail below with reference to the figures and the specific embodiments. The step numbers in the following embodiments are provided only for convenience of illustration, the order between the steps is not limited at all, and the execution order of each step in the embodiments can be adaptively adjusted according to the understanding of those skilled in the art.
The embodiment of the invention provides an individual non-uniform-speed rotating irradiation method, which comprises the following steps:
controlling the rotation of a rotary motor by using the constructed non-uniform rotation control code and the preset number of rotation turns so as to enable the electronic wire to perform non-uniform rotation irradiation in the transverse circumferential direction of the human body; the electron beam is generated by the linear accelerator according to a preset hop count.
The rotating motor is used for enabling the electronic wire to move relative to the human body in the transverse circumferential direction of the human body, so that the non-uniform-speed rotating irradiation of the electronic wire on the human body is realized, namely the rotating motor can control the linear accelerator to move around the human body in the transverse circumferential direction of the human body at a non-uniform speed, or the rotating motor can control the human body to rotate in a non-uniform speed manner; in the present embodiment, the latter is preferably selected, and specifically, the rotating motor drives the rotating disk to rotate at a non-uniform speed, so as to rotate the human body at a non-uniform speed.
Further as a preferred embodiment of the present invention, the non-uniform rotation control code is a control code constructed by the following code construction steps:
controlling the rotation of the rotary motor to obtain the irradiation dose received by the plurality of dose detectors under the constant-speed rotation of different rotating speeds at each equal-part angle; the equal-part angle is obtained by dividing equal parts of angles by taking the human body model as a center in the transverse circumferential direction of the human body model, the human body model is a 3D printed human body model with a plurality of dose monitoring holes in the body part, and the dose detectors are respectively arranged in the dose monitoring holes in a one-to-one correspondence manner;
calculating the optimal rotating speed of each equal angle corresponding to the target irradiation dose by using the irradiation doses received by the plurality of dose detectors under the constant-speed rotation of each equal angle at different rotating speeds;
and generating corresponding non-uniform rotation control codes according to the calculated optimal rotation speed of each equal angle.
Further, as a preferred embodiment of the present invention, the step of calculating the optimal rotation speed of each equal portion angle corresponding to the target irradiation dose by using the irradiation doses received by the plurality of dose detectors under the uniform rotation of each equal portion angle at different rotation speeds specifically includes:
calculating the total irradiation dose received by each dose detector under the constant rotation at different rotation speeds according to the irradiation dose received by each dose detector under the constant rotation at different rotation speeds at each equal division angle;
obtaining the absolute difference between the total irradiation dose and the target irradiation dose received by each dose detector under constant-speed rotation at different rotating speeds according to the required target irradiation dose;
and finding out the minimum value of the sum of absolute differences between the total irradiation dose and the target irradiation dose received by the plurality of dose detectors, thereby obtaining the optimal rotating speed of the target irradiation dose corresponding to each equal-divided angle.
Further, as a preferred embodiment of the present invention, the step of obtaining the optimal rotation speed of each equal-divided angle corresponding to the target irradiation dose by finding the minimum value of the sum of absolute differences between the total irradiation dose received by the plurality of dose detectors and the target irradiation dose is specifically:
and finding out the minimum value of the sum of absolute differences between the total irradiation dose and the target irradiation dose received by the plurality of dose detectors by adopting a simulated annealing algorithm, thereby obtaining the optimal rotating speed of the target irradiation dose corresponding to each equal-part angle.
Further as a preferred embodiment of the present invention, the 3D printing human body model is a 3D printing human body model constructed by the following model construction steps:
acquiring a CT scanning image of a human body;
constructing a corresponding 3D human body virtual model according to the CT scanning image of the human body; the position of a dose monitoring hole is marked on the 3D human body virtual model;
and printing the corresponding 3D printing human body model according to the STL file of the 3D human body virtual model.
Further, as a preferred embodiment of the present invention, the step of constructing a corresponding 3D human body virtual model according to the CT scan image of the human body specifically includes:
and constructing a corresponding 3D human body virtual model according to the CT scanning image of the human body by using three-dimensional reconstruction software, and generating an STL file of the 3D human body virtual model.
The process of the present invention is described in further detail below with reference to specific preferred embodiments.
As shown in FIG. 1, an individualized non-uniform rotation irradiation method for electron beam whole body radiotherapy specifically comprises the following steps.
Step one, constructing a non-uniform rotation control code.
S100, constructing a 3D printing human body model.
Specifically, the step S100 preferably includes:
s1001, acquiring a CT scanning image of a human body;
specifically, the whole body of the patient is scanned by using the CT, a whole body CT scanning image of the human body of the patient is obtained, and a doctor can determine the irradiation depth below the whole body skin of the patient and delineate some interested organs (such as lymph nodes) according to the tumor condition of the patient in the CT scanning image;
s1002, constructing a corresponding 3D human body virtual model according to the CT scanning image of the human body; the position of a dose monitoring hole is marked on the 3D human body virtual model;
specifically, a corresponding 3D human body virtual model is constructed according to a CT scanning image of a human body by utilizing three-dimensional reconstruction software, and an STL file of the 3D human body virtual model is generated; according to the determined subcutaneous irradiation depth and some drawn interesting organs, setting dose monitoring holes at corresponding positions for placing a multi-channel dose detector in the future, namely marking the positions of the determined subcutaneous irradiation depth and some drawn interesting organs on the 3D human body virtual model with the dose monitoring holes;
s1003, printing a corresponding 3D printing human body model according to the STL file of the 3D human body virtual model;
specifically, after the STL file of the generated 3D human body virtual model is sent to a 3D printer, the model is printed out by the 3D printer, and therefore the 3D printing human body model is obtained. Therefore, the printed 3D printing human body model is provided with a plurality of dosage monitoring holes as shown in figure 2;
s101, controlling the rotation of a rotary motor to obtain the irradiation dose of a plurality of dose detectors under the constant-speed rotation of different rotating speeds at each equal-part angle; the equal-part angle is obtained by dividing equal parts of angles by taking the human body model as a center in the transverse circumferential direction of the human body model, the human body model is a 3D printed human body model with a plurality of dose monitoring holes in the body part, and the dose detectors are respectively arranged in the dose monitoring holes in a one-to-one correspondence manner;
specifically, firstly, the printed 3D printed human body model is placed on a rotating disc (as shown in fig. 3), and a multichannel dose detector is placed in a plurality of dose monitoring holes on the 3D printed human body model, that is, one dose detector is arranged in one dose monitoring hole, and one dose detector is equivalent to one dose measuring point and used for measuring the irradiation dose received by the corresponding body part;
in this embodiment, there are n dose measurement points on the 3D printed human body model, and then the expression of the dose values measured by the n dose measurement points is as follows:
D_1，D_2，………，D_n
that is, D _ n represents the dose value measured for the nth dose measurement point;
then, equally angularly dividing the body of the 3D printed human body model into a plurality of parts in the transverse circumferential direction (namely, the transverse circumferential direction, as shown in fig. 4), namely equally dividing the angles of the human body model by taking the human body model as the center in the transverse circumferential direction of the human body model to obtain m equal-part angles; in the present embodiment, m is 14, as shown in fig. 5;
then, the linear accelerator for generating electron beams and the rotary motor work synchronously (in this embodiment, the rotary motor is used for driving the rotary disk to rotate); the rotating disc rotates at a constant speed at a plurality of different rotating speeds by controlling the rotation of the rotating motor, namely, the rotating speeds respectively have t1、t2、t3、……、tkK rotational speeds, then the rotating discs are respectively made to follow t1、t2、t3、……、tkCarrying out uniform rotation, and simultaneously recording the irradiation dose of the corresponding equal-part angle at different rotating speeds by the dose detector in each equal-part angle in the rotation process;
in the present embodiment, in the j-th rotation speed (j ═ 1, 2, 3, … …, k) tjWhen the rotation speed is constant, the rotation speed is equal to the ith equal-dividing angle (i is 1, 2, 3, … … and m), and the expression of the dose values measured by the n dose measuring points is as follows:
Dij_1，Dij_2，………，Dij_n
for example, control of the rotating disc to t1The rotation speed (i.e. 1 st rotation speed) is rotated at a constant speed, then every time the rotation speed is rotated by 1 equal part of angle, the n dose detectors record the received irradiation dose, for example, the 1 st dose detector records the irradiation dose at t1Under the uniform rotation of the rotating speed, the irradiation doses of each rotation at 1 equal part of angle are respectively as follows:
D11_1，D21_1，………，D141_1
similarly, under the uniform rotation of the jth rotating speed, the irradiation doses of the nth dose detector in each rotation through 1 equal division angle are respectively as follows:
D1j_n，D2j_n，………，D14j_n
therefore, the rotating disc rotates at a constant speed at different rotating speeds respectively by controlling the rotation of the rotating motor, and each rotation is carried out while the rotating disc rotatesWhen the irradiation dose is measured and collected once by the n dose detectors after passing through the 1 equal-part angle, the irradiation dose received by the dose detectors under the constant-speed rotation of each equal-part angle at different rotating speeds (namely under the constant-speed rotation of different rotating speeds and when the irradiation dose passes through each equal-part angle), namely D, can be obtainedij_1，Dij_2，………，Dij_n；
S102, calculating the optimal rotating speed of each equal angle corresponding to the target irradiation dose by using the irradiation doses received by the plurality of dose detectors under the constant-speed rotation of each equal angle at different rotating speeds;
specifically, the step S102 preferably includes:
s1021, calculating the total irradiation dose received by each dose detector under the constant-speed rotation at different rotating speeds according to the irradiation dose received by each dose detector under the constant-speed rotation at different rotating speeds at each equal-divided angle;
specifically, when the rotating disk rotates at a constant speed at different rotation speeds for 1 rotation, the expression of the total value of the irradiation dose (i.e., the total dose) received by the p-th dose measurement point (p ═ 1, 2, 3, … …, n) is as follows:
that is, for the 1 st dosimetry point, the total dose of radiation to which the disk is subjected during 1 revolution is:
similarly, for the nth dose measurement point, the total dose of radiation to which the disk is subjected during 1 rotation is:
wherein j belongs to {1, 2, 3, … …, k }, i.e. in the formula, each equal angle can correspond to different rotation speeds; it can be seen that in this step, it is necessary to first use the uniform rotation of each equal angle at different rotation speedsTurning off the irradiation dose received by a plurality of dose detectors, and calculating the total irradiation dose (total irradiation dose) received by each dose detector under the condition of 1-turn rotation and the uniform rotation of each equal-part angle at any rotation speed;
s1022, irradiating according to the required target dose D0Obtaining the absolute difference between the total irradiation dose received by each dose detector and the target irradiation dose under the constant-speed rotation at different rotating speeds;
specifically, let D be the clinically desirable uniform dose to be obtained on the patient0I.e. the dose at each measurement point of the body is D0(since the dose at each measurement point is completely made to be D0Dose uniformity in the inventive solution is only relatively uniform, not absolutely uniform), then the total dose D _1 and D of the 1 st dosimetry point are measured0The absolute difference between them is:
Δ_1＝|D0-D_1|
similarly, the total irradiation doses D _2 and D at the 2 nd dose measurement point0The absolute difference between them is:
Δ_2＝|D0-D_2|
by analogy, the total irradiation doses D _ n and D of the nth dose measurement point0The absolute difference between them is:
Δ_n＝|D0-D_n|
s1023, finding out the minimum value of the sum of absolute differences between the total irradiation dose and the target irradiation dose received by the plurality of dose detectors, and thus obtaining the optimal rotating speed of the target irradiation dose corresponding to each equal-divided angle;
specifically, the total irradiation dose and D based on the respective dose measurement points described in the above step S10220The absolute difference between the two to obtain the total irradiation dose and D of each dose measurement point0The sum of the absolute differences between them is:
then, the minimum Δ, i.e., the minimum value of Δ, is found by using a simulated annealing algorithm
Thereby determining the velocity corresponding to each of the aliquot angles, at which time the determined velocity corresponds to the target dose D for each of the aliquot angles0The optimum rotational speed of the motor;
s103, generating corresponding non-uniform rotation control codes according to the calculated optimal rotation speed of each equal-divided angle; at this time, the generated non-uniform rotation control code is a motor control code which is only suitable for the individualized non-uniform rotation of the patient;
specifically, in order to ensure quality, after the required non-uniform rotation control code is generated, the method also comprises the steps of acquiring the required rotation number and the beam-out hop number; wherein, the acquiring step preferably comprises:
and controlling the rotation of the rotary motor according to the generated non-uniform rotation control code so as to rotate the rotary disk, and simultaneously, generating an emitted electron beam by the linear accelerator until a clinically expected treatment dosage is obtained on the human body model, and recording the number of rotation turns of the rotary disk and the number of beam-out hops of the linear accelerator.
And step two, the constructed non-uniform rotation control code is applied on line.
S201, controlling the rotation of a rotating motor by using the constructed non-uniform rotation control code and the preset number of rotation turns (namely the number of rotation turns recorded) so as to enable the electronic wire to perform non-uniform rotation irradiation in the transverse circumferential direction of the human body; in this step, the electron beam is generated by the linear accelerator according to a preset number of hops (i.e. the number of outgoing beam hops recorded above);
specifically, a patient (a real human body) is placed on a rotating disc, the rotating motor is controlled to rotate according to an individualized non-uniform rotation control code, a preset number of rotation turns is rotated, meanwhile, a linear accelerator generates electronic wires according to a preset number of jumps, the electronic wires are enabled to carry out non-uniform rotation irradiation on the patient in the transverse circumferential direction of the human body, different equal-portion angles correspond to different rotating speeds, and finally, a relatively uniform irradiated dose is obtained on the patient.
From the above, by using the individual non-uniform rotation irradiation method of the present invention, the corresponding individual non-uniform rotation motor control code can be constructed according to the actual figure type of the patient, so as to perform non-uniform electron beam rotation irradiation on the patient, thereby effectively improving the uniformity of the irradiation dose received by the patient, and having great significance for improving the curative effect of electron beam whole body radiotherapy and reducing the toxic and side effects of radiotherapy. In addition, the method can accurately obtain the irradiated dose of some interested organs, is convenient for prognosis evaluation, and can be used for accurately guiding the later dose of certain lymph nodes and improving the treatment precision.
The embodiment of the invention also provides an individualized non-uniform-speed rotating irradiation system, which comprises:
the control unit is used for controlling the rotation of the rotary motor by utilizing the constructed non-uniform rotation control code and the preset number of rotation turns so as to enable the electronic wire to perform non-uniform rotation irradiation in the transverse circumferential direction of the human body; the electron beam is generated by the linear accelerator according to a preset hop count.
Further, as a preferred embodiment of the present invention, the present invention further includes a first constructing unit for constructing a non-uniform rotation control code, where the first constructing unit includes:
the first acquisition module is used for controlling the rotation of the rotary motor so as to acquire the irradiation dose received by the plurality of dose detectors under the uniform rotation of different rotating speeds at each equal-dividing angle; the equal-part angle is obtained by dividing equal parts of angles by taking the human body model as a center in the transverse circumferential direction of the human body model, the human body model is a 3D printed human body model with a plurality of dose monitoring holes in the body part, and the dose detectors are respectively arranged in the dose monitoring holes in a one-to-one correspondence manner;
the calculation module is used for calculating the optimal rotating speed of each equal angle corresponding to the target irradiation dose by utilizing the irradiation doses received by the plurality of dose detectors under the constant-speed rotation of each equal angle at different rotating speeds;
and the generating module is used for generating corresponding non-uniform rotation control codes according to the calculated optimal rotating speed of each equal part angle.
Further as a preferred embodiment of the present invention, the system further comprises a second construction unit for constructing the 3D printed human body model, the second construction unit comprising:
the second acquisition module is used for acquiring a CT scanning image of a human body;
the building module is used for building a corresponding 3D human body virtual model according to the CT scanning image of the human body; the position of a dose monitoring hole is marked on the 3D human body virtual model;
and the printing module is used for printing the corresponding 3D printing human body model according to the STL file of the 3D human body virtual model.
The contents in the above method embodiments are all applicable to the present system embodiment, the functions specifically implemented by the present system embodiment are the same as those in the above method embodiment, and the beneficial effects achieved by the present system embodiment are also the same as those achieved by the above method embodiment.
As shown in fig. 6, an embodiment of the present invention further provides a terminal, including:
at least one processor 301;
at least one memory 302 for storing at least one program;
when executed by the at least one processor 301, causes the at least one processor 301 to implement the one individualized non-uniform rotational irradiation method.
The contents in the foregoing method embodiments are all applicable to this terminal embodiment, the functions specifically implemented by this terminal embodiment are the same as those in the foregoing method embodiments, and the beneficial effects achieved by this terminal embodiment are also the same as those achieved by the foregoing method embodiments.
While the preferred embodiments of the present invention have been illustrated and described, it will be understood by those skilled in the art that various changes in form and details may be made therein without departing from the spirit and scope of the invention as defined by the appended claims.
Claims (2)
1. An individualized non-uniform rotational illumination system, comprising:
the control unit is used for controlling the rotation of the rotary motor by utilizing the constructed non-uniform rotation control code and the preset number of rotation turns so as to enable the electronic wire to perform non-uniform rotation irradiation in the transverse circumferential direction of the human body; the electron beam is generated by the linear accelerator according to a preset hop count;
the device further comprises a first construction unit used for constructing the non-uniform rotation control code, wherein the first construction unit comprises:
the first acquisition module is used for controlling the rotation of the rotary motor so as to acquire the irradiation dose received by the plurality of dose detectors under the uniform rotation of different rotating speeds at each equal-dividing angle; the equal-part angle is obtained by dividing equal parts of angles by taking the human body model as a center in the transverse circumferential direction of the human body model, the human body model is a 3D printed human body model with a plurality of dose monitoring holes in the body part, and the dose detectors are respectively arranged in the dose monitoring holes in a one-to-one correspondence manner;
the calculation module is used for calculating the optimal rotating speed of each equal angle corresponding to the target irradiation dose by utilizing the irradiation doses received by the plurality of dose detectors under the constant-speed rotation of each equal angle at different rotating speeds;
and the generating module is used for generating corresponding non-uniform rotation control codes according to the calculated optimal rotating speed of each equal part angle.
2. The individualized non-uniform velocity rotary illumination system according to claim 1, further comprising a second construction unit for constructing a 3D printed phantom, said second construction unit comprising:
the second acquisition module is used for acquiring a CT scanning image of a human body;
the building module is used for building a corresponding 3D human body virtual model according to the CT scanning image of the human body; the position of a dose monitoring hole is marked on the 3D human body virtual model;
and the printing module is used for printing the corresponding 3D printing human body model according to the STL file of the 3D human body virtual model.
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