CN109077770A - Lung therapeutic device with treatment channel - Google Patents
Lung therapeutic device with treatment channel Download PDFInfo
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- CN109077770A CN109077770A CN201710454466.2A CN201710454466A CN109077770A CN 109077770 A CN109077770 A CN 109077770A CN 201710454466 A CN201710454466 A CN 201710454466A CN 109077770 A CN109077770 A CN 109077770A
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- plug members
- therapeutic device
- passage component
- lung therapeutic
- treatment channel
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/12—Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
- A61B17/12022—Occluding by internal devices, e.g. balloons or releasable wires
- A61B17/12027—Type of occlusion
- A61B17/1204—Type of occlusion temporary occlusion
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/12—Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
- A61B17/12022—Occluding by internal devices, e.g. balloons or releasable wires
- A61B17/12131—Occluding by internal devices, e.g. balloons or releasable wires characterised by the type of occluding device
- A61B17/1214—Coils or wires
- A61B17/12145—Coils or wires having a pre-set deployed three-dimensional shape
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/12—Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
- A61B17/12022—Occluding by internal devices, e.g. balloons or releasable wires
- A61B17/12131—Occluding by internal devices, e.g. balloons or releasable wires characterised by the type of occluding device
- A61B17/12181—Occluding by internal devices, e.g. balloons or releasable wires characterised by the type of occluding device formed by fluidized, gelatinous or cellular remodelable materials, e.g. embolic liquids, foams or extracellular matrices
- A61B17/12195—Occluding by internal devices, e.g. balloons or releasable wires characterised by the type of occluding device formed by fluidized, gelatinous or cellular remodelable materials, e.g. embolic liquids, foams or extracellular matrices comprising a curable material
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M31/00—Devices for introducing or retaining media, e.g. remedies, in cavities of the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B2017/00831—Material properties
- A61B2017/00862—Material properties elastic or resilient
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B2017/00831—Material properties
- A61B2017/00867—Material properties shape memory effect
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B2017/00831—Material properties
- A61B2017/00889—Material properties antimicrobial, disinfectant
Abstract
The invention discloses a kind of lung therapeutic devices in band treatment channel, are mainly made of plug members, passage component and one or two switch block；Wherein, the side fitting of the plug members is located in inner bronchial wall；The passage component runs through the plug members；Part of the plug members in addition to the passage component is airtight on the direction along bronchus length；The one or both ends of the passage component are arranged in one or two switch blocks；Wherein, the end of the passage component is closed under normal conditions and closed to the switch block, and after the switch block is opened by external force, the passage component perforation, the lung therapeutic device is formed along bronchus length direction and is connected to.Lung therapeutic device of the invention, which is placed in the bronchus of pulmonary tuberculosis target hole region proximal end, can completely cut off outside air, and provides channel and aspirated or conveyed drug therapy to the remaining mycobacterium tuberculosis in pulmonary tuberculosis target cavity.
Description
Technical field
The present invention relates to a kind of interventional therapy device, especially one kind pulmonary tuberculosis target hole region can be carried out blocking to
The lung therapeutic device with treatment channel of starvation.
Background technique
Pulmonary tuberculosis is a kind of disease for seriously endangering human health, it is the pneumonia infection caused by mycobacterium tuberculosis
Disease.Mycobacterium tuberculosis is in latence or persistent infection state after infecting human body mostly, it can be in infection host
The intracellular defense reaction for escaping host to mass propagation and and host reach the delicate balance of one kind, the infected is in life
Whenever it is likely to fall ill.Under normal circumstances, 10% the infected would develop into active tuberculosis.One untreated
Active tuberculosis patient, 10-15 people can be infected within 1 year.
After antibiotic is invented and control theory lungy and technology, clinical conditions level and grind
The progress studied carefully, it is commonly used due to effective chemotherapeutics (isoniazid, rifampin, pyrazinamide, streptomysin, ethambutol etc.)
With BCG vaccine in worldwide popularization, so that disease incidence lungy was once once reducing, so that people optimistically think, knot
Core disease the same with smallpox will be utterly destroyed by the mankind.However global tuberculosis gets damp again comprehensively since the 1990s, disease incidence
Go up again in worldwide, WHO in 1993 announces that tuberculosis is in " global emergency state ", and appeals " to take rapidly
Action is waged a struggle with tuberculosis crisis ", drug resistance and multi-drug resistance tuberculosis are the significant threats in current Tuberculosis control work.
Resistant tuberculosis refers to the intracorporal mycobacterium tuberculosis of tuberculosis patient to a kind of a line antituberculotic --- isoniazid, benefit
Good fortune is put down, drug resistance occurs for ethambutol, pyrazinamide and streptomysin.And multi-drug resistance tuberculosis then refers at least to isoniazid and benefit
The flat drug resistance simultaneously of good fortune.Since the lethal effect of isoniazid and rifampicin against Mycobacterium mycobacteria is most strong, multi-drug resistance tuberculosis
It is a kind of even more serious drug resistance of tuberculosis type.
According to the statistics of the World Health Organization, tuberculosis is only after AIDS virus/AIDS, in the whole world by single biography
Maximum killer caused by metachromia pathogen.For 2013, the whole world has 9,000,000 people to suffer from tuberculosis in 1 year, and 1,500,000 people are dead
In the disease.It is counted according to another Chinese sick control centre's Tubercufosis control center, current China has more than 500,000,000 people and infected tuberculosis point
Branch bacillus, there is 1,000,000 new cases every year, more than 54000 people because of tuberculosis death.China is in 2007~2008 in the whole nation
The drug resistance of tuberculosis Baseline that range is carried out shows that multi-drug resistant rate is 8.32% in Chinese pulmonary tuberculosis patient.Accordingly
Estimation, annual new hair more than 10 ten thousand people of Drug resistant pulmonary tubeculosis patient of China.
One of tuberculotherapy key points and difficulties be control again, refractory and Drug resistant pulmonary tubeculosis, thus to prevention lungy
More acute challenge and higher requirement are proposed with treatment.Using conventional administration route (oral, intramuscular injection, intravenous) to resistance to
Multiple medicine tuberculosis patient carries out chemotherapy and has the following deficiencies: that 1. treatment cycle is long: a common tuberculosis patient, treatment cycle are general
It is 6 months；Multi-drug resistance tuberculosis people treatment cycle 18~24 months or even 36 months is 3~6 times of common tuberculosis patient；Make
For one of most important Second line Drug, injection (such as kanamycins, capreomycin etc.) is using time at least six more than the moon.②
Therapeutic agent is more, and adverse reaction rate is high: the first-line drug for treating common tuberculosis patient is about 4~5 kinds, and adverse reaction rate is not
It is high；And at least 5~6 kinds of multi-drug resistance tuberculosis people therapeutic agent, and be the higher two wires antituberculotic of adverse reaction rate, such as roll up
Aspergillin, seromycin, protionamide etc..3. cure rate is low: currently, common tuberculosis patient cure rate is mostly 85% or more,
China is more than 90%；And the highest cure rate of multi-drug resistance tuberculosis people only has 50~60% or so；This means that existing item
The multi-drug resistance tuberculosis people for having half is unable to get healing under part.
It is local fiber hyperblastosis, blood because most course of disease of multi-drug resistance tuberculosis patient is longer there are disadvantages described above
For reduction, the osmotic absorption of drug is influenced, lesion is locally extremely difficult to kill the effective blood drug concentration of mycobacterium tuberculosis, so
Conventional administration route (oral, intramuscular injection, intravenous) chemotherapy effect is poor, many years protracted course of disease, lung function progressive detraction, tuberculosis point
Branch bacillus lasting masculin becomes lifelong excreter.Interventional therapeutic technique is the emerging therapeutic means that developed recently gets up, and is to control
The multi-drug resistant phthisical effective means in cavity is treated, be applied to clinical and obtains certain curative effect.
The interventional therapy of pulmonary tuberculosis transtracheal bronchus approach, through Bronchofiberscope guide perfusion antituberculotic, method be
After conventional Fibro-bronchoscopy test, insertion bronchoscope to target segmenta bronchopulmonalia is open, and seal wire, conduit are introduced under radioscopy and is inserted
Enter in cavity, exit seal wire, keep the catheter injects a small amount of contrast agent, it was demonstrated that for target cavity, injects antituberculotic, have net
Change cavity, promotes mycobacterium tuberculosis to turn out cloudy, the effect of void closing.However antituberculosis therapy is proved effective slowly, and tuberculous cavity is normal
Often there are multiple fistula mouths to communicate with bronchus, the mycobacterium tuberculosis that do not turn out cloudy be easy through fistula mouth by bronchogenic spread to lung its
Its region.
The interventional therapy of pulmonary tuberculosis percutaneous puncture, method are chest CT scans, determine the position in cavity, local infiltration anesthesia
After puncture inserting needle, CT is swept again, determine puncture needle in cavity, suction cavity in sputum, then by antituberculotic injection cavity in.
The current Major Clinical of this method is applied to be not suitable for the cavity that fiberbronchoscope or branchofiberoscope can not reach, but
There are the risks of the complication after puncture such as pneumothorax.
There are still following problems for current pulmonary tuberculosis interventional therapy:
The interventional therapy of pulmonary tuberculosis transtracheal bronchus approach carries out pulmonary tuberculosis target cavity just with the mode of intervention
Drug therapy is conveyed, is practically without and achievees the effect that kill mycobacterium tuberculosis completely, there is the tuberculosis branches that do not turn out cloudy
The risk that bacillus is further sent out.
The interventional therapy of pulmonary tuberculosis percutaneous puncture, although having aspirated the mycobacterium tuberculosis in pulmonary tuberculosis target cavity in art,
But the risk of mycobacterium tuberculosis bacterium remnants is remained, the wind of the complication such as pneumothorax is had existed while in addition puncture
Danger occurs.
Summary of the invention
The present invention provides a kind of lung therapeutic devices, place the lung in the bronchus of pulmonary tuberculosis target hole region proximal end and control
Device is treated, pulmonary tuberculosis target hole region, the extraneous air circulation with pulmonary tuberculosis target cavity of isolation, so that pulmonary tuberculosis target can be blocked
Mycobacterium tuberculosis in cavity is because anoxic is irreproducible, so as to effectively limit or reduce the quantity of mycobacterium tuberculosis.Together
When, which also provides the channel of an alternative opening and closing, to provide to the remaining tuberculosis in pulmonary tuberculosis target cavity
The physical channel of drug therapy is aspirated or conveyed to mycobacteria；The phlegm in target cavity can be pumped out by this channel
Liquid further cooperates operative treatment, so that remaining mycobacterium tuberculosis is destroyed completely, promotes pulmonary tuberculosis target cavity final
Closure；Or drug therapy is carried out by the cooperation of this channel, the drug concentration in pulmonary tuberculosis target hole region can be improved, so that
Remaining mycobacterium tuberculosis is turned out cloudy, and the final closure in pulmonary tuberculosis target cavity is promoted.
In the present invention, proximal end refers to that the lung therapeutic device with treatment channel close to one end of performer, distally refers to band treatment
The lung therapeutic device in channel is far from one end of performer.
Technical scheme is as follows:
The lung therapeutic device in a kind of band treatment channel, mainly by plug members, passage component and one or two switch portion
Part composition；Wherein, the plug members have side and end face, and the side fitting of the plug members is located in inner bronchial wall
On；The passage component runs through the plug members, and the passage component forms at the both ends of the plug members and runs through
The connection of the plug members；Part of the plug members in addition to the passage component is on the direction along bronchus length
It is airtight；The one or both ends of the passage component are arranged in one or two switch blocks；Wherein, the switch portion
The end of the passage component is closed under normal conditions and closed to part, the lung therapeutic device formed along bronchus length direction it is airtight,
After the switch block is opened by external force, the passage component perforation, which forms along bronchus length direction connects
It is logical.
In one embodiment, there is cavity, the center point of the both ends of the surface of the plug members inside the plug members
Not She You hole, the passage component is connected to the cavity by described two holes and formed.
In another embodiment, the passage component is the tube body being arranged in the plug members, the choking portion
The center of the both ends of the surface of part is respectively equipped with hole, and the both ends of the tube body and the edge in described two holes are respectively fixedly connected with, and
The tube body can stretch with the shape of the plug members.
In a preferred embodiment, switch block described in wherein at least one is bell shape, and using with shape note
The elastic material for recalling function is made.
In a preferred embodiment, the plug members include frame and cover film layer on frame surface.
In another preferred embodiment, the plug members are using balloon structure made from elastic polymer material.
In a further preferred embodiment, the plug members are made using swollen material.
In some embodiments, the switch block and the plug members use the tubing one with shape memory function
Body cutting is made, or is made using the silk material integrated woven with shape memory function；Or, the switch block, which uses, to be had
The macromolecule tubing of shape memory function is made, and is attached using technique for sticking and the plug members.
When the plug members use elastic polymer or swell material, the passage component uses high molecular material
Tubing obtained and plug members welding are made.
In some embodiments, the frame facet is cylindrical side, one or two end face of the plug members
There is certain length and reduced diameter on the direction coaxial with the cylindrical side until forming the end, such as
For circular cone end face, the cylindrical side and two circular cone end faces are integrally formed.The advantages of both ends are cone shape is by pressing
Contracting state become expansion state process can than more gentle, be because the conical surface can slow boot state variation, be not in
Product discharges the situation of process " front jumping ".In general, the overall framework shape of plugging device product is cylinder, the end of cylindrical frame in the industry
Portion is plane, due to being retracted to the control unit of a small diameter by the expansion state of major diameter suddenly, can make this
Diameter change is excessive, the phenomenon that product often said in the industry release process " front jumping " occurs.That is product " spring " once
It jumps out.
Preferably, the frame is hollow cylinder, has the end face of side peace, and passage component setting exists
The edge of the frame.
Preferably, the frictional force for increasing the lung therapeutic device and inner bronchial wall is provided on the side of the plug members
Fixed structure.
It preferably, further include control unit, the control unit is integrated on the switch block, the control unit energy
Enough grasped by instrument is fixed, and the edge of the plug members is arranged in the switch block for being integrated with the control unit.
Compared with prior art, beneficial effects of the present invention are as follows:
Lung therapeutic device of the invention, which is placed in the bronchus of pulmonary tuberculosis target hole region proximal end, can block pulmonary tuberculosis
Target hole region, the extraneous air circulation with pulmonary tuberculosis target cavity of isolation, so that the mycobacterium tuberculosis in pulmonary tuberculosis target cavity
Because anoxic is irreproducible, so as to effectively limit or reduce the quantity of mycobacterium tuberculosis；Meanwhile the lung therapeutic device also provides
The channel of one alternative opening and closing being made of passage component and switch block, to provide to the remnants in pulmonary tuberculosis target cavity
Mycobacterium tuberculosis is aspirated or is conveyed the physical channel of drug therapy.
Certainly, it implements any of the products of the present invention and does not necessarily require achieving all the advantages described above at the same time.
Detailed description of the invention
Fig. 1 is the structural schematic diagram of the lung therapeutic device of the embodiment of the present invention one；
Fig. 2 is placed in the bronchus of pulmonary tuberculosis target hole region for the lung therapeutic device of the embodiment of the present invention one and switch portion
Part is the schematic diagram closed；
Fig. 3 is placed in the bronchus of pulmonary tuberculosis target hole region for the lung therapeutic device of the embodiment of the present invention one and switch portion
Part is the schematic diagram opened；
Fig. 4 is the structural schematic diagram of the lung therapeutic device of the embodiment of the present invention two；
Fig. 5 is the structural schematic diagram of the lung therapeutic device of the embodiment of the present invention three；
Fig. 6 is the structural schematic diagram of the lung therapeutic device of the embodiment of the present invention four；
Fig. 7 is the structural schematic diagram of the lung therapeutic device of the embodiment of the present invention five.
Specific embodiment
The present invention provides one kind pulmonary tuberculosis target hole region can be blocked band treat channel lung therapeutic device,
Can starvation so that mycobacterium tuberculosis in pulmonary tuberculosis target cavity because anoxic is irreproducible, so as to effectively limit
Or reduce the quantity of mycobacterium tuberculosis.Meanwhile the lung therapeutic device can also provide the channel of an alternative opening and closing, logical
Drug therapy is aspirated or is conveyed to the sputum in pulmonary tuberculosis target cavity when road is opened, pumps out the sputum in target cavity,
So that remaining mycobacterium tuberculosis is destroyed completely, promote the final closure in pulmonary tuberculosis target cavity；And cooperation carries out drug
Treatment improves the drug concentration in pulmonary tuberculosis target hole region, so that remaining mycobacterium tuberculosis is turned out cloudy, promotes pulmonary tuberculosis target empty
Hole is finally closed.When channel is closed, entire lung therapeutic device realizes the air-tightness along bronchus length direction.
Below with specific embodiment, the present invention will be further described.
Embodiment one
Fig. 1 is the structural schematic diagram of the lung therapeutic device of the embodiment of the present invention one.The lung with treatment channel of the present embodiment
Therapeutic device 10 is made of plug members 11, passage component 12 and switch block 13, and plug members 11 have the circle positioned at middle part
Column side and the two circular cone end faces coaxial positioned at the cylindrical side both ends and with the cylindrical side, the cylindrical side and
Two circular cone end faces are integrally formed, and passage component 12 is through plug members 11 and positioned at the center of cylindrical side and circular cone end face
At axis, the both ends of passage component 12 are flushed with plug members 11；One end of passage component 12, switch portion is arranged in switch block 13
The end of the closed channel component 12 under normal conditions of part 13, the plug members 11 are on the length direction along passage component 12 at this time
Be it is airtight, after 13 stress of switch block can passive open, after switch block 13 is opened, passage component 12 penetrate through.
In the present embodiment, plug members 11 include frame 111 and cover film layer 112 on 111 surface of frame.Its
In,
Frame 111 is hollow grid framework in the present embodiment, can be using the superlastic with shape memory function
Tubing made of property material, is laser-cut into the tubing with certain lines, and strut through mold and heat treatment shaping and
At；Alternatively, frame 111 can also be woven at network management using silk material made of the elastic material with shape memory function,
And it is loaded into mold and heat treatment shaping and is made；In addition, frame 111 can also be using the super-elasticity with shape memory function
Silk material made of material works out forming directly on mold, and thermally treated sizing is made.Such moulding process be it is existing at
Cooking technique, details are not described herein again.
Film layer 112 can be made using high molecular materials such as silicon rubber, polyurethane, terylene, polyester, polytetrafluoroethylene (PTFE).?
After frame 111 completes, the techniques such as suture, bonding, dipping, spraying, thermal-adhering is taken to be covered with a tunic on 111 surface of frame
Plug members 11 can be made in layer 112.Such coating technique is existing mature technology, and details are not described herein again.
Can be used in plug members 11 two of the production of passage component 12 are open-ended, in conjunction with the hollow of plug members
Structure forms a channel；More preferably, in order to enable passage component 12 more has guiding performance, passage component can also be included in
One section of metal elastic reed pipe of laser welding between the opening of two ends of plug members 11, metal elastic reed pipe can be with plug members
11 shape is stretched, and such setting may make passage component 12 can be with 11 longitudinal contraction of plug members, so as to by band
The lung therapeutic device 10 for treating channel is accommodated into bronchoscope or visual catheter lumen, realizes the operation of intervention operation.
The shape of switch block 13 is the shape convenient for opening after by external force, is preferably in bell shape, thus has one
Fixed guiding performance.Switch block 13 can be used the elastic material with shape memory function and be made, after switch block 13 is made
It is welded again with plug members 11 or be bonded；More preferably, switch block 13 can also be by the superlastic with shape memory function
Property material made of tubing pass through and be made with the one cutting of plug members 11.
As shown in Fig. 2, the lung therapeutic device 10 in band treatment channel is placed in pulmonary tuberculosis through bronchoscope or visual conduit
After in the bronchus 70 of target hole region, since switch block 13 is initially in off state, which can form lung
The blocking of tuberculosis target hole region, air 80 enter less than in the pulmonary tuberculosis target hole region of 10 distal end of lung therapeutic device, completely cut off
The extraneous air circulation with pulmonary tuberculosis target cavity, so that mycobacterium tuberculosis in pulmonary tuberculosis target is empty is because anoxic is irreproducible,
So as to effectively limit or reduce the quantity of mycobacterium tuberculosis.
In order to further cooperate the operative treatment to pulmonary tuberculosis target cavity, treatment conduit 90 can pass through the lung with treatment channel
The switch block 13 of therapeutic device 10 enters in the lung therapeutic device 10 with treatment channel, as shown in Figure 3.Pass through switch block 13
Bell shape guiding role, make switch block 13 by treatment conduit 90 squeezing action, so that switch block 13 is beaten
It opens, and treatment conduit 90 is guided to enter in passage component 12, by the guidance of passage component 12, treating conduit 90 can control into band
In the pulmonary tuberculosis target hole region for treating 10 distal end of lung therapeutic device in channel.Conduit 90 is treated to enter in pulmonary tuberculosis target hole region
Afterwards, the sputum in pulmonary tuberculosis target cavity can be aspirated by treatment conduit 90, so that remaining mycobacterium tuberculosis quilt
It wipes up, promotes the final closure in pulmonary tuberculosis target cavity；Or drug is conveyed by treatment conduit 90 and is treated, it can be improved
Drug concentration in pulmonary tuberculosis target hole region promotes pulmonary tuberculosis target cavity finally to close so that remaining mycobacterium tuberculosis is turned out cloudy
It closes.After treatment, after the lung therapeutic device extraction with treatment channel, switch block 13 can restore initially to close treatment conduit 90
Closed state forms blocking of the lung therapeutic device 10 with treatment channel to pulmonary tuberculosis target hole region, avoids pulmonary tuberculosis target empty
Interior remaining mycobacterium tuberculosis regains oxygen and breeds again.Further conveying drug or suction are controlled several times for cooperation
It treats, mycobacterium tuberculosis may make to turn out cloudy, the process for accelerating pulmonary tuberculosis target cavity to be finally closed.
Embodiment two
Refer to Fig. 4, the lung therapeutic device 20 with treatment channel of the present embodiment by plug members 21, passage component 22,
First switch component 23 and second switch component 24 form, and the plug members 21 of the embodiment include frame 211 and cover
The film layer 212 on 211 surface of frame.The main distinction of the present embodiment and embodiment one is to be respectively provided at the both ends of passage component 22
Switch block.Also, as shown in figure 4, second switch component 24 does not use horn mouth, and it is the flat mouth shape structure shunk.
At the beginning of the first switch component 23 and second switch component 24 of the lung therapeutic device 20 with treatment channel of the present embodiment
Beginning is in off state, therefore the both ends of passage component 22 are closed, and such setting can be to avoid sputum in pulmonary tuberculosis target hole region
Storage stays in passage component 22, to prevent the obstruction of passage component 22 and treatment failure.
In order to further cooperate the operative treatment to pulmonary tuberculosis target cavity, a treatment conduit can pass through the lung with treatment channel
The first switch component 23 of therapeutic device 10 enters in passage component 22, and passes through the guiding role of second switch component 24, controls
Treating conduit can enter in the pulmonary tuberculosis target hole region of 20 distal end of lung therapeutic device with treatment channel.Treatment conduit enters lung knot
After in core target hole region, the sputum in pulmonary tuberculosis target cavity can be aspirated by treatment conduit, so that remaining knot
Core mycobacteria is destroyed completely, promotes the final closure in pulmonary tuberculosis target cavity；Or conveying drug carry out treatment lung can be improved
Drug concentration in tuberculosis target hole region promotes the final closure in pulmonary tuberculosis target cavity so that remaining mycobacterium tuberculosis is turned out cloudy.
After treatment, treatment conduit is after the lung therapeutic device extraction with treatment channel, first switch component 23 and second switch portion
Part 24 can restore initial closed state, form the lung therapeutic device 20 with treatment channel and block up to pulmonary tuberculosis target hole region
Plug, while but also the both ends of passage component 22 are closed.Cooperation further conveys drug or suction therapy several times, may make knot
Core mycobacteria is turned out cloudy, the process for accelerating pulmonary tuberculosis target cavity to be finally closed.
Embodiment three
The lung therapeutic device 30 with treatment channel of the present embodiment is by plug members 31, passage component 32, switch block 33
It is formed with control unit 35, the plug members 31 of the embodiment include frame 311 and cover film layer on 311 surface of frame
312, as shown in Figure 5.
The present embodiment and embodiment one the difference is that, the shape of plug members 31 is hollow cylinder, also, is switched
Control unit 35, switch block 33 and 35 eccentric setting of control unit and the side that plug members 31 are set are integrated on component 33
Edge, control unit 35 act also as the attachment device of grasping part and removal process.The shape of control unit 35 is e.g. as shown in Figure 5
Hook shape.
In order to further cooperate to the further treatment of pulmonary tuberculosis target cavity, catching device or biopsy commonly used in the trade can be used
The instruments such as pincers carry out grasping fixation to control unit 35, while treating conduit can be by the lung therapeutic device 30 with treatment channel
Gap between switch block 33 and control unit 35 enters in passage component 32, and treatment conduit enters pulmonary tuberculosis target hole region
After interior, the sputum in pulmonary tuberculosis target cavity can be aspirated by treatment conduit, so that remaining mycobacterium tuberculosis quilt
It wipes up, promotes the final closure in pulmonary tuberculosis target cavity；Or conveying drug carry out treatment pulmonary tuberculosis target hole area can be improved
Drug concentration in domain promotes the final closure in pulmonary tuberculosis target cavity so that remaining mycobacterium tuberculosis is turned out cloudy.After treatment,
Conduit is treated after the lung therapeutic device extraction with treatment channel, can restore initially to close between switch block 33 and control unit 35
Closed state forms blocking of the lung therapeutic device 30 with treatment channel to pulmonary tuberculosis target hole region, avoids pulmonary tuberculosis target empty
Interior remaining mycobacterium tuberculosis regains oxygen and breeds again.Further conveying drug or suction are controlled several times for cooperation
It treats, mycobacterium tuberculosis may make to turn out cloudy, the process for accelerating pulmonary tuberculosis target cavity to be finally closed.
Meanwhile if the lung therapeutic device 30 that need to treat channel to the band recycles, which be can function as
The attachment device of removal process is right after carrying out grasping connection to control unit with catching device or biopsy forceps etc. commonly used in the trade
Lung therapeutic device 30 with treatment channel is recycled.
The control unit 35 of the present embodiment is hook shape, is grabbed in addition, the shape of control unit 35 can also be with common
The structures such as ball head, Elastic buckle, magnetic connector, the lasso trick shape that device or biopsy forceps etc. match are caught, so set, can
Instrument caused by prevent from treating conduit during turning on the switch component 33 shifts.
Example IV
As shown in fig. 6, the present embodiment with treatment channel lung therapeutic device 40 by plug members 41, passage component 42,
Switch block 43 forms.
It is different from embodiment one, the plug members 41 of the embodiment using silicon rubber, polyurethane, PEBAX, polyimides,
The elastic polymer materials such as nylon, PET or PTFE are made, and the pipe of such elastic polymer material is placed on to the mould of correspondingly-shaped
In tool, mold is placed in the heat-conducting medium heated, and pipe is stretched while inflation sacculus and then forms balloon structure, sacculus
Manufacture craft be existing mature technology, be no longer described in detail herein.
Passage component 42 is made using tubing made from high molecular material and with 41 ultrasonic bonding of plug members, switch portion
Part 43 generallys use the macromolecule tubing with shape memory function and is made, and is connected using technique for sticking with plug members 41
It connects.
Embodiment five
The lung therapeutic device 50 with treatment channel of the present embodiment is by plug members 51, passage component 52, switch block 53
Composition, the cylindrical side of the plug members 51 of the embodiment includes fixed structure 513, as shown in Figure 7.
The plug members 51 of the present embodiment are handed over using polycaprolactone-polyethylene glycol block copolymer or polycaprolactone-poly- third
Ester-polyethers ternary atactic copolymer etc. is swollen high molecular material and is made；Passage component 52 uses tubing made from high molecular material,
Passage component 52 and plug members 51 are connected with each other using adhesion process.Switch block 53 is using the height with shape memory function
Molecule tubing is made, and switch block 53 is attached using adhesion process with plug members 51.
The lung therapeutic device 50 with treatment channel is delivered to suitable position by bronchoscope or visual conduit, is blocked
Component 51 meets liquid expansion, may make that the lung therapeutic device 50 with treatment channel is tightly attached to inner bronchial wall, fixed structure 513 can
Increase the frictional force of instrument and inner bronchial wall, so that the lung therapeutic device 50 in anti-stop-band treatment channel shifts.The embodiment
The form of fixed structure 513 is dot spinous process structure, in addition, the form of fixed structure 513 can also be other in the industry for anchor thorn etc.
Common fixed form.
Present invention disclosed above preferred embodiment is only intended to help to illustrate the present invention.There is no detailed for preferred embodiment
All details are described, are not limited the invention to the specific embodiments described.Obviously, according to the content of this specification,
It can make many modifications and variations.These embodiments are chosen and specifically described to this specification, is in order to better explain the present invention
Principle and practical application, so that skilled artisan be enable to better understand and utilize the present invention.The present invention is only
It is limited by claims and its full scope and equivalent.
Claims (11)
1. a kind of lung therapeutic device in band treatment channel, which is characterized in that mainly by plug members, passage component and one or two
A switch block composition；Wherein, the plug members have side and end face, and the side fitting of the plug members is located in branch
On inner surface of trachea；The passage component runs through the plug members, and the passage component is at the both ends of the plug members
Form the connection for running through the plug members；Part of the plug members in addition to the passage component is along bronchus length
Direction on be airtight；The one or both ends of the passage component are arranged in one or two switch blocks；Wherein, institute
The end that switch block closes under normal conditions and closes the passage component is stated, the lung therapeutic device is along bronchus length direction shape
At airtight, after the switch block is opened by external force, the passage component perforation, the lung therapeutic device is along bronchus length direction
Form connection.
2. the lung therapeutic device as described in claim 1 with treatment channel, which is characterized in that have inside the plug members
Cavity, the center of the both ends of the surface of the plug members are respectively equipped with hole, and the passage component is by described two holes and the cavity
Connection is formed.
3. the lung therapeutic device as described in claim 1 with treatment channel, which is characterized in that the passage component is that setting exists
Tube body in the plug members, the center of the both ends of the surface of the plug members are respectively equipped with hole, the both ends of the tube body and institute
The edge for stating two holes is respectively fixedly connected with, and the tube body can stretch with the shape of the plug members.
4. the lung therapeutic device as described in claim 1 with treatment channel, which is characterized in that switched described in wherein at least one
Component is bell shape, and is made using the elastic material with shape memory function.
5. the lung therapeutic device as described in claim 1 with treatment channel, which is characterized in that the plug members include frame
And cover film layer on frame surface.
6. the lung therapeutic device as described in claim 1 with treatment channel, which is characterized in that the plug members are using bullet
Balloon structure made from property high molecular material.
7. the lung therapeutic device as described in claim 1 with treatment channel, which is characterized in that the plug members are using swelling
Material is made.
8. the lung therapeutic device as described in claim 1 with treatment channel, which is characterized in that the switch block is blocked up with described
Plunger member uses the tubing with shape memory function integrally to cut and is made, or using the silk material one with shape memory function
Body braiding is made；Or, the switch block use with shape memory function macromolecule tubing be made, using technique for sticking with
The plug members are attached.
9. the lung therapeutic device with treatment channel as claimed in claims 6 or 7, which is characterized in that the passage component uses
Tubing made from high molecular material and plug members welding are made.
10. the lung therapeutic device as described in claim 1 with treatment channel, which is characterized in that the side of the plug members
On be provided with the fixed structure for increasing the frictional force of the lung therapeutic device and inner bronchial wall.
11. the lung therapeutic device as described in claim 1 with treatment channel, which is characterized in that it further include control unit, it is described
Control unit is integrated on the switch block, and the control unit can be grasped by instrument and be fixed, and is integrated with the control unit
The edge of the plug members is arranged in the switch block of part.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710454466.2A CN109077770A (en) | 2017-06-14 | 2017-06-14 | Lung therapeutic device with treatment channel |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710454466.2A CN109077770A (en) | 2017-06-14 | 2017-06-14 | Lung therapeutic device with treatment channel |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN109077770A true CN109077770A (en) | 2018-12-25 |
Family
ID=64839018
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201710454466.2A Withdrawn CN109077770A (en) | 2017-06-14 | 2017-06-14 | Lung therapeutic device with treatment channel |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN109077770A (en) |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20040060563A1 (en) * | 2001-03-02 | 2004-04-01 | Alan Rapacki | Bronchial flow control devices and methods of use |
| US20070225747A1 (en) * | 2006-03-08 | 2007-09-27 | Pulmonx | Methods and devices to induce controlled atelectasis and hypoxic pulmonary vasoconstriction |
| CN207693625U (en) * | 2017-06-14 | 2018-08-07 | 朔健医疗器械（上海）有限公司 | Lung therapeutic device with treatment channel |
-
2017
- 2017-06-14 CN CN201710454466.2A patent/CN109077770A/en not_active Withdrawn
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20040060563A1 (en) * | 2001-03-02 | 2004-04-01 | Alan Rapacki | Bronchial flow control devices and methods of use |
| US20070225747A1 (en) * | 2006-03-08 | 2007-09-27 | Pulmonx | Methods and devices to induce controlled atelectasis and hypoxic pulmonary vasoconstriction |
| CN207693625U (en) * | 2017-06-14 | 2018-08-07 | 朔健医疗器械（上海）有限公司 | Lung therapeutic device with treatment channel |
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| TA01 | Transfer of patent application right |
Effective date of registration: 20191114 Address after: 101300 501, building 8, yard 12, Juyuan Middle Road, Mapo Town, Shunyi District, Beijing Applicant after: Beijing saishute Medical Equipment Co.,Ltd. Address before: 201815 Shanghai City, Jiading District Xing Xian Lu No. 1180 Building 5 room 225 two Applicant before: SHUOJIAN MEDICAL DEVICES (SHANGHAI) CO.,LTD. |
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