CN109072306A - 分离的核酸及应用 - Google Patents

分离的核酸及应用 Download PDF

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Publication number
CN109072306A
CN109072306A CN201680083629.4A CN201680083629A CN109072306A CN 109072306 A CN109072306 A CN 109072306A CN 201680083629 A CN201680083629 A CN 201680083629A CN 109072306 A CN109072306 A CN 109072306A
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China
Prior art keywords
nucleic acid
acid sequence
abundance
sequence
sequences
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Pending
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CN201680083629.4A
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English (en)
Inventor
仲文迪
张林爽
郑智俊
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Shanghai Realbio Technology Co ltd
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Shanghai Realbio Technology Co ltd
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Publication of CN109072306A publication Critical patent/CN109072306A/zh
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids

Abstract

一组分离的核酸，其包括以下两个核酸序列簇中的至少一个：第一核酸序列簇，该簇中的核酸序列与SEQ ID NO：1‑151所示的序列一一对应，每条该簇中的核酸序列与其对应的SEQ ID NO：1‑151中的序列的序列相似性不小于90％；第二核酸序列簇，该簇中的核酸序列与SEQ ID NO：152‑233所示的序列一一对应，每条该簇中的核酸序列与其对应的SEQ ID NO：152‑233中的序列的序列相似性不小于90％。相较于大肠癌患者群体，所称的分离的核酸在健康群体中显著富集，能够作为健康群体和大肠癌患者群体的区分标志。

Description

PCT国内申请，说明书已公开。

Claims (28)

  1. PCT国内申请，权利要求书已公开。
CN201680083629.4A 2016-03-17 2016-03-17 分离的核酸及应用 Pending CN109072306A (zh)

Applications Claiming Priority (1)

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PCT/CN2016/076577 WO2017156739A1 (zh) 2016-03-17 2016-03-17 分离的核酸及应用

Publications (1)

Publication Number Publication Date
CN109072306A true CN109072306A (zh) 2018-12-21

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CN201680083629.4A Pending CN109072306A (zh) 2016-03-17 2016-03-17 分离的核酸及应用

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CN (1) CN109072306A (zh)
WO (1) WO2017156739A1 (zh)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113637660A (zh) * 2021-08-05 2021-11-12 云南师范大学 一种β-半乳糖苷酶GalNC3-89及其制备方法和应用
CN113969290A (zh) * 2021-11-16 2022-01-25 中南大学 一种深海细菌来源的α-葡萄糖苷酶QsGH97a及其编码基因与应用
CN114317716A (zh) * 2021-12-31 2022-04-12 上海锐翌生物科技有限公司 痛风症标志基因及其应用

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114317718A (zh) * 2021-12-31 2022-04-12 上海锐翌生物科技有限公司 类风湿性关节炎标志ko及其应用

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WO2015018307A1 (en) * 2013-08-06 2015-02-12 Bgi Shenzhen Co., Limited Biomarkers for colorectal cancer
CN105132518A (zh) * 2015-09-30 2015-12-09 上海锐翌生物科技有限公司 大肠癌标志物及其应用
EP2955232A1 (en) * 2014-06-12 2015-12-16 Peer Bork Method for diagnosing adenomas and/or colorectal cancer (CRC) based on analyzing the gut microbiome
CN105296590A (zh) * 2015-09-30 2016-02-03 上海锐翌生物科技有限公司 大肠癌标志物及其应用

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CN104039982A (zh) * 2012-08-01 2014-09-10 深圳华大基因研究院 一种分析微生物群落组成的方法和装置
WO2015018307A1 (en) * 2013-08-06 2015-02-12 Bgi Shenzhen Co., Limited Biomarkers for colorectal cancer
WO2015018308A1 (en) * 2013-08-06 2015-02-12 BGI Shenzhen Co.,Limited Biomarkers for colorectal cancer
EP2955232A1 (en) * 2014-06-12 2015-12-16 Peer Bork Method for diagnosing adenomas and/or colorectal cancer (CRC) based on analyzing the gut microbiome
CN105132518A (zh) * 2015-09-30 2015-12-09 上海锐翌生物科技有限公司 大肠癌标志物及其应用
CN105296590A (zh) * 2015-09-30 2016-02-03 上海锐翌生物科技有限公司 大肠癌标志物及其应用

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Title
陈伟光: ""结直肠癌相关微生态菌群及其与宿主相互作用机制研究"", 《中国学位论文全文数据库》 *

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113637660A (zh) * 2021-08-05 2021-11-12 云南师范大学 一种β-半乳糖苷酶GalNC3-89及其制备方法和应用
CN113637660B (zh) * 2021-08-05 2023-09-08 云南师范大学 一种β-半乳糖苷酶GalNC3-89及其制备方法和应用
CN113969290A (zh) * 2021-11-16 2022-01-25 中南大学 一种深海细菌来源的α-葡萄糖苷酶QsGH97a及其编码基因与应用
CN113969290B (zh) * 2021-11-16 2023-06-30 中南大学 一种深海细菌来源的α-葡萄糖苷酶QsGH97a及其编码基因与应用
CN114317716A (zh) * 2021-12-31 2022-04-12 上海锐翌生物科技有限公司 痛风症标志基因及其应用

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Address after: Room 202-3 and 302, Building No. 138, Xinjunhuan Road, Minhang District, Shanghai, 20114

Applicant after: SHANGHAI REALBIO TECHNOLOGY Co.,Ltd.

Address before: Room 119, 1st floor, 3058 Pusan Road, Pudong New Area, Shanghai 200050

Applicant before: SHANGHAI REALBIO TECHNOLOGY Co.,Ltd.

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Application publication date: 20181221