CN109069036A - Pulse wave detection device, vital information measurement device, pulse wave detecting method and pulse wave detect program - Google Patents
Pulse wave detection device, vital information measurement device, pulse wave detecting method and pulse wave detect program Download PDFInfo
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- CN109069036A CN109069036A CN201780026138.0A CN201780026138A CN109069036A CN 109069036 A CN109069036 A CN 109069036A CN 201780026138 A CN201780026138 A CN 201780026138A CN 109069036 A CN109069036 A CN 109069036A
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- A—HUMAN NECESSITIES
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- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/02—Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
- A61B5/021—Measuring pressure in heart or blood vessels
- A61B5/022—Measuring pressure in heart or blood vessels by applying pressure to close blood vessels, e.g. against the skin; Ophthalmodynamometers
- A61B5/0225—Measuring pressure in heart or blood vessels by applying pressure to close blood vessels, e.g. against the skin; Ophthalmodynamometers the pressure being controlled by electric signals, e.g. derived from Korotkoff sounds
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- A—HUMAN NECESSITIES
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- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/02—Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
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- A—HUMAN NECESSITIES
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- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/02—Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
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- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/02—Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
- A61B5/021—Measuring pressure in heart or blood vessels
- A61B5/02108—Measuring pressure in heart or blood vessels from analysis of pulse wave characteristics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/02—Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
- A61B5/021—Measuring pressure in heart or blood vessels
- A61B5/022—Measuring pressure in heart or blood vessels by applying pressure to close blood vessels, e.g. against the skin; Ophthalmodynamometers
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/103—Detecting, measuring or recording devices for testing the shape, pattern, colour, size or movement of the body or parts thereof, for diagnostic purposes
- A61B5/11—Measuring movement of the entire body or parts thereof, e.g. head or hand tremor, mobility of a limb
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- A61B5/11—Measuring movement of the entire body or parts thereof, e.g. head or hand tremor, mobility of a limb
- A61B5/1126—Measuring movement of the entire body or parts thereof, e.g. head or hand tremor, mobility of a limb using a particular sensing technique
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/24—Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
- A61B5/316—Modalities, i.e. specific diagnostic methods
- A61B5/369—Electroencephalography [EEG]
- A61B5/377—Electroencephalography [EEG] using evoked responses
- A61B5/378—Visual stimuli
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- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/24—Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
- A61B5/316—Modalities, i.e. specific diagnostic methods
- A61B5/369—Electroencephalography [EEG]
- A61B5/377—Electroencephalography [EEG] using evoked responses
- A61B5/38—Acoustic or auditory stimuli
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
- A61B5/6801—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be attached to or worn on the body surface
- A61B5/6843—Monitoring or controlling sensor contact pressure
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
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- A61B5/6801—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be attached to or worn on the body surface
- A61B5/6813—Specially adapted to be attached to a specific body part
- A61B5/6824—Arm or wrist
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01L—MEASURING FORCE, STRESS, TORQUE, WORK, MECHANICAL POWER, MECHANICAL EFFICIENCY, OR FLUID PRESSURE
- G01L27/00—Testing or calibrating of apparatus for measuring fluid pressure
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01L—MEASURING FORCE, STRESS, TORQUE, WORK, MECHANICAL POWER, MECHANICAL EFFICIENCY, OR FLUID PRESSURE
- G01L27/00—Testing or calibrating of apparatus for measuring fluid pressure
- G01L27/002—Calibrating, i.e. establishing true relation between transducer output value and value to be measured, zeroing, linearising or span error determination
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01L—MEASURING FORCE, STRESS, TORQUE, WORK, MECHANICAL POWER, MECHANICAL EFFICIENCY, OR FLUID PRESSURE
- G01L27/00—Testing or calibrating of apparatus for measuring fluid pressure
- G01L27/002—Calibrating, i.e. establishing true relation between transducer output value and value to be measured, zeroing, linearising or span error determination
- G01L27/005—Apparatus for calibrating pressure sensors
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Abstract
The present invention provides pulse wave detection device, vital information measurement device, pulse wave detecting method and pulse wave and detects program, can accurately detect pressure pulse wave in the state that flexible sensor is pressed on body surface face.The pulse wave detection device includes: flexible strain transducer (4), has the multiple strain test elements (41) being arranged on substrate (40)；Air bag (3), fixed strain transducer (4)；And control unit (12), based on the strain detecting signal detected in the increased boost process of internal pressure for making air bag (3) by each strain test element (41), at the time of judging that the deformation of the detection faces (42) of strain transducer (4) stops, and reference level will be set as by the strain detecting signal that each strain test element (41) detects at the moment.Control unit (12) is based on the correction that said reference level carries out the strain detecting signal detected after the above-mentioned moment by each strain test element (41), and the strain detecting signal after correction is converted to pressure signal and is stored in memory (15).
Description
Technical field
The present invention relates to the detections of pulse wave detection device, vital information measurement device, pulse wave detecting method and pulse wave
Program.
Background technique
A kind of known vital information measurement device can be such that the arteries such as the Radial artery of sensor and wrist are passed through
In the state of the body surface face contact of organism part, information measurement pulse, heartbeat or the blood pressure detected by the sensor is utilized
Etc. biological informations (referring to patent document 1-3).
A kind of blood pressure sensor is described in patent document 1, is included multiple magneto-resistance effect elements, is matched in two dimension shape
It sets on flexible substrate, is used as resistance value to detect for that will strain；And pressing mechanism, by the flexible substrate to body surface face
Pressing.
As the method for using blood pressure sensor measurement blood pressure, patent document 1 discloses following method: using by preparatory
The related data of the resistance value of blood pressure and magneto-resistance effect element obtained from actual measurement, the resistance that will be detected by magneto-resistance effect element
Value is converted to pressure value.
A kind of pulse wave detection sensor is described in patent document 2, includes flexible strip, with band-like flexibility pressure
The state configuration that electric piece intersects；And elastic component, it is fixed on the back side of flexible strip.
A kind of device is described in patent document 3, is had using biological informations, the sensors such as sensor measurement blood pressures
Multiple magneto-resistance effect elements on flexible substrate are configured in two dimension shape.
Patent document 1: Japanese Patent Laid-Open Publication 2011-244938
Patent document 2: Japanese Patent Laid-Open Publication 2004-208711
Patent document 3: Japanese Patent Laid-Open Publication 2002-148132
Biology is measured according to flexible sensor and body surface face contact is made as documented by patent document 1-3
The structure of information can make the wearing feeling of sensor good.Further, since calculating life can be detected using more elements
Information needed for object information, so can be improved the computational accuracy of biological information.
The method of the pulse wave of one of the information calculated as detection for biological information, is generally known tensioned measurement side
Formula.Tonometry mode is such as under type: under the state (tonometry state) for moderately flattening artery, using sensor from
Artery detects pressure pulse wave (the pressure vibration wave transmitted with beating to body surface face).Therefore, it is necessary to by sensor to body
The pressing mechanism of surface pressing and the driving portion for driving the pressing mechanism.
A kind of vital information measurement device is described in patent document 1 comprising: blood pressure sensor；Pressing mechanism, will
Blood pressure sensor is pressed to body surface face；And driving portion, drive the pressing mechanism.The blood pressure sensor utilizes magneto-resistance effect element
The tensile stress generated in the sensor with beating is detected as resistance value, and the resistance value is converted into blood pressure.
Further, since the blood pressure sensor recorded in patent document 1 has flexibility, so pressing on by blood pressure sensor
In the state of body surface face, to the big of the strain of magneto-resistance effect element application due to multiple magneto-resistance effect element respective positions are different
Small difference.Therefore, if not considering the difference of this strain, pressure pulse wave can not accurately be detected.
Patent document 2 does not imagine the case where pressing flexible strip to body surface face, does not account for flexible strip pressing on body surface
The detection method of pressure pulse wave in the state of face.
Patent document 3 does not imagine the case where pressing flexible substrate to body surface face, does not account for pressing on flexible substrate
The detection method of pressure pulse wave in the state of body surface face.
Summary of the invention
The present invention is to complete in view of the above problems, and its purpose is to provide a kind of pulse wave detection devices, biology letter
Measurement device, the control program of the control method of pulse wave detection device and pulse wave detection device are ceased, can be scratched that will have
The sensor of property accurately detects pressure pulse wave in the state of pressing on body surface face.
Pulse wave detection device of the invention includes: flexible strain transducer, and there are be arranged on substrate multiple to answer
Become detecting element；Flexible pressing member presses the strain transducer, and the fixed strain sensing to the body surface face of biology
Device；Driving portion drives the pressing member；Control unit is pressed, the driving portion is controlled, the pressing member is controlled and is answered by described in
Become the pressing force that sensor is pressed to the body surface face；Stop timing judging part is deformed, based on making by the pressing control unit
The strain detecting signal detected respectively in the increased boost process of pressing force by the multiple strain test element, judgement
The deformation stop timing that the deformation of the detection faces of the strain transducer stops；Correction unit, will the deformation stop timing by
The strain detecting signal that the multiple strain test element detects respectively is set as reference level, based on the benchmark electricity
It is flat believed after the deformation stop timing by the first strain detecting that the multiple strain test element detects respectively
Number correction；And pressing creation portion, pressure signal is generated according to the first strain detecting signal after the correction.
Vital information measurement device of the invention includes: the pulse wave detection device；And biological information calculation part, base
Biological information is calculated in the pressure signal generated by the pressing creation portion.
The pressing member of pulse wave detecting method of the invention using flexible strain transducer and flexibility, the strain
Sensor has multiple strain test elements for being arranged on substrate, and the pressing member is by the strain transducer to biology
The pressing of body surface face, and the fixed strain transducer, the pulse wave detecting method include: to answer the pressing member by described in
Become the pressing force that sensor is pressed to the body surface face to increase；Based in the increased boost process of the pressing force by described more
The strain detecting signal that a strain test element detects respectively judges what the deformation of the detection faces of the strain transducer stopped
The step of deforming the stop timing；Described in being detected respectively in the deformation stop timing as the multiple strain test element
Strain detecting signal is set as reference level, is carried out after the deformation stop timing based on the reference level by described more
The step of correction for the first strain detecting signal that a strain test element detects respectively；And according to the institute after the correction
State the step of the first strain detecting signal generates pressure signal.
The pressing member of pulse wave detection program of the invention using flexible strain transducer and flexibility, the strain
Sensor has arrangement multiple strain test elements in the same plane, and the pressing member is by the strain transducer to life
The body surface face of object presses, and the fixed strain transducer, and the pulse wave detection program is for making computer execute following step
Rapid: the pressing force for pressing the pressing member strain transducer to the body surface face increases；Based in the pressing
The strain detecting signal detected respectively in the increased boost process of power by the multiple strain test element, judges the strain
The deformation stop timing that the deformation of the detection faces of sensor stops；It will be in the deformation stop timing by the multiple strain detecting
The strain detecting signal that element detects respectively is set as reference level, is carried out based on the reference level in the deformation
The step of correction of the first strain detecting signal detected respectively after stop timing by the multiple strain test element；With
And according to after the correction the first strain detecting signal generate pressure signal the step of.
In accordance with the invention it is possible to provide the control of pulse wave detection device, vital information measurement device, pulse wave detection device
The control program of method processed and pulse wave detection device, can be in the state that flexible sensor is pressed on to body surface face
Under, accurately detect pressure pulse wave.
Detailed description of the invention
Fig. 1 be indicate an embodiment of the present invention vital information measurement device included by pulse wave test section 100
The schematic diagram of surface structure.
Fig. 2 is the schematic diagram for indicating the brief configuration of strain transducer 4 shown in FIG. 1.
Fig. 3 is the figure for indicating the modular structure of vital information measurement device of present embodiment.
The process of movement when Fig. 4 is the METHOD FOR CONTINUOUS DETERMINATION mode for illustrating the vital information measurement device of present embodiment
Figure.
Fig. 5 is to indicate any element column as included by strain transducer 4 in the state of carrying out the step S1 processing of Fig. 4
The figure of an example of the strain detecting signal detected.
Fig. 6 is an example for the strain detecting signal for indicating that any element column detect as included by strain transducer 4
Figure.
Fig. 7 is to indicate to be detected after deforming the stop timing by arbitrary strain test element 41 and first after correcting answers
Become the figure of the relationship between the internal pressure of the air bag 3 when the detection for detecting signal and the first strain detecting signal.
Description of symbols:
100 pulse wave test sections
1 cabinet
2 supporting members
3 air bags
4 strain transducers
5 adhesive layers
40 substrates
41 strain test elements
42 detection faces
X, the direction Y
T Radial artery
Pressure sensor in 10
11 pumps
12 control units
13 display units
14 operation portions
15 memories
F1 pressure conversion curve
During T1, T2
Specific embodiment
Hereinafter, the embodiments of the present invention will be described with reference to the drawings.
Fig. 1 be indicate an embodiment of the present invention vital information measurement device included by pulse wave test section 100
The schematic diagram of surface structure.The vital information measurement device of present embodiment is worn on organism part using band (not shown)
(being the wrist of user's left hand in the example of Fig. 1) carries out using the organism part exists in inside as biological information
The artery (being Radial artery T in the example of Fig. 1) of measure object.
Pulse wave test section 100 includes: the viscous of strain transducer 4, air bag 3, fixed air bag 3 and strain transducer 4
Layer 5, the flat supporting member 2 of support air bag 3 and cabinet 1 are connect, which keeps supporting member 2,3 and of air bag
Strain transducer 4.
Air bag 3 controls internal air capacity (internal pressure) using pump (not shown) in the example in fig 1 to be hemispherical.
Air bag 3 is the flexure member for changing its shape deformation by internal pressure.The shape of air bag 3 is not limited to hemispherical.
As shown in Figure 1, air bag 3 is played as pressing member in the state that pulse wave test section 100 is fixed on wrist
Function, the pressing member press the detection faces 42 of strain transducer 4 to the body surface face of organism part (wrist).
Fig. 2 is the schematic diagram for indicating the brief configuration of strain transducer 4 shown in FIG. 1.
Strain transducer 4 includes flexible substrate 40 and the multiple strain detectings being arranged on the surface of substrate 40
Element 41.The surface of substrate 40 is plane.In the example in figure 2, multiple strain test elements 41 are arranged as by along direction X
The element that multiple strain test elements 41 of arrangement are constituted arranges (multiple along the structure of the direction Y arrangement multiple row orthogonal with direction X
Strain test element 41 is in the structure of two dimension shape arrangement).As long as strain transducer 4 is on the substrate 40 at least formed with a column element
Column.
Strain test element 41 is the element for the strain that any direction detected on the surface of substrate 40 generates, and uses benefit
The deformeter of strain is detected with the resistance variations of metal or semiconductor or utilizes magnetoresistance documented by patent document 1
To detect the element etc. of strain.
The face for being combined with the respective surface of multiple strain test elements 41 constitutes the detection faces 42 of strain transducer 4.
The formation of substrate 40 has the opposing face on the surface of strain test element 41 to utilize by the bonding structure such as bonding agent or adhesive tape
The adhesive layer 5 that part is constituted is fixed on air bag 3.Therefore, if air bag 3 deforms, strain transducer 4 is also deformed.
The vital information measurement device of present embodiment direction Y shown in Fig. 2 is along the measurement pair as biological information
In the state of the Radial artery T of elephant, the detection faces 42 of strain transducer 4 are pressed to body surface face to use.
Under installation condition shown in Fig. 1, the detection faces 42 of strain transducer 4 included by pulse wave test section 100
The skin contact of a part and the wrist of user.If the air capacity injected in this state to air bag 3 increases, empty
Airbag 3 expands and change in shape, and with the change in shape of air bag 3, strain transducer 4 is deformed and pressed to body surface face.Air
Pressing force when air bag 3 presses strain transducer 4 to body surface face is pressed in bag 3.
Fig. 3 is the figure for indicating the modular structure of vital information measurement device of present embodiment.
Vital information measurement device includes: pulse wave test section 100, interior pressure sensor 10, pump 11, integrally carries out to device
Control unit 12, display unit 13, operation portion 14 and the memory 15 of overall control.
Pump 11 controls the air capacity (internal pressure of air bag 3) injected to air bag 3 based on the instruction of control unit 12.Pump 11
Constitute the driving portion of driving air bag 3.
Interior pressure sensor 10 detects the internal pressure of air bag 3, and the internal pressure that will test is input to control unit 12.
Display unit 13 is used to show the various information such as biological information, such as is made of liquid crystal display device etc..
Operation portion 14 is for the interface to 12 input indicative signal of control unit, by being used to indicate various movements
Button etc. is constituted, and above-mentioned various movements include the measurement of biological information.
The storage of memory 15 includes the various information by the calculated biological information of control unit 12, such as by structures such as flash memories
At.Memory 15 can be the memory that can be dismounted.
Control unit 12 is constituted based on processor, and the ROM including program performed by storage processor etc. is (read-only to deposit
Reservoir: Read Only Memory) and as working storage RAM (random access memory: Random Access
Memory) etc..
The program includes that pulse wave detects program.ROM is the non-transitory (non-of computer-readable medium
Transitory) storage medium.The program for being stored in ROM can be downloaded and be stored from other equipment via network.
In the ROM of control unit 12, strain transducer 4 in the state that the detection faces 42 of strain transducer 4 are flat
The output signal of each strain test element 41 is by a reference value (hereinafter referred to as strain a reference value) as each strain test element 41
It is stored.Vital information measurement device manufacture when strain transducer 4 be fixed on air bag 3 before, the strain a reference value by
The strain transducer 4 surveys and is stored in ROM.
Each strain detecting member of strain a reference value pair of strain sensors 4 of the control unit 12 based on each strain test element 41
The output signal of part 41 is corrected and (is converted to the relative value relative to strain a reference value), and the output signal after correction is made
Strain detecting signal to be detected by each strain test element 41 is pocessed.
Control unit 12 executes the program that program is detected comprising pulse wave by processor, and as pressing control unit, deformation
Stop timing judging part, correction unit, pressing creation portion and biological information calculation part function.
Pulse wave detection device is made of pulse wave test section 100, pump 11 and control unit 12.
Hereinafter, being illustrated to the movement of the vital information measurement device of present embodiment.The biology letter of present embodiment
Measurement device is ceased with METHOD FOR CONTINUOUS DETERMINATION mode, which detects pressure pulse wave for beating every time, and being based on should
Pressure pulse wave calculates biological information and stores.
The process of movement when Fig. 4 is the METHOD FOR CONTINUOUS DETERMINATION mode for illustrating the vital information measurement device of present embodiment
Figure.
If vital information measurement device is worn on wrist and has carried out the instruction to start the measurement of biological information, control unit
12 control pumps 11, discharge the internal pressure of air bag 3 and make its (step S1) identical as atmospheric pressure.
After step S1, control unit 12 obtains the detection signal of interior pressure sensor 10, and acquired detection is believed
Number it is set as a reference value (internal pressure a reference value) (step S2) of the internal pressure of air bag 3.It is detected as a result, by interior pressure sensor 10
The internal pressure of air bag 3 is pocessed as the relative value relative to the internal pressure a reference value.
Fig. 5 is to indicate the arbitrary member as included by strain transducer 4 in the state of carrying out the processing of step S1 of Fig. 4
The figure of an example for the strain detecting signal that part column detect.The horizontal axis of Fig. 5 indicates to constitute each strain test element 41 of element column
Direction X on position, the longitudinal axis of Fig. 5 indicates the strain detecting signal detected by each strain test element 41.
In addition, detection signal shown in fig. 5 indicates the above-mentioned strain a reference value correction based on the ROM for being stored in control unit 12
Value afterwards.
Herein, by the state of opposite side warpage of the detection faces 42 of strain transducer 4 towards substrate 40 by each strain
The symbol for the strain detecting signal that detecting element 41 detects is set as just.In the state of carrying out the processing of step S1, such as Fig. 1 institute
Show, detection faces 42 become along air bag 3 surface shape towards 40 side warpage of substrate state.Therefore, as shown in figure 5, answering
The symbol for becoming detection signal is negative.Further, since strain transducer 4 has flexibility, so detection faces 42 are curved because of position difference
Qu Chengdu is different.Therefore, as shown in figure 5, obtaining the bending degree with the allocation position of the element from each strain test element 41
Corresponding output.
Upon step s 2, the control of control unit 12 pump 11, starts the boosting process for gradually increasing the internal pressure of air bag 3
(step S3).The information of the internal pressure of air bag 3 is established with the moment and is associated with and is stored in memory 15 by control unit 12.
After starting boosting process, when detecting strain using each strain test element 41 of strain transducer 4, control
Portion 12 processed by the strain detecting signal detected by each strain test element 41 of strain transducer 4 (strain detecting signal group) with
Detection moment, which is established, to be associated with and is temporarily stored in RAM (step S4).
After step s4, control unit 12 judges multiple strain detecting signal groups whether are stored in RAM, if storage
Multiple strain detecting signal groups (step S5: yes), then follow the steps the processing of S6, if not stored multiple strain detecting signals
Group (step S5: no), then make that processing returns to step S4.
If the internal pressure of air bag 3 is continuously increased, the entirety and body surface face contact of detection faces 42.In air bag 3
Force down and the spring rate of air bag 3 and strain transducer 4 it is sufficiently small compared with the spring rate in body surface face in the state of, detection faces 42
According to the shape distortion in body surface face.Hereafter, if the internal pressure of air bag 3 increases and the spring rate of air bag 3 and strain transducer 4
The spring rate in body surface face is become larger than, then the shape of detection faces 42 hardly changes.
In step s 6, control unit 12 is based on the strain detecting signal group for being stored in RAM, judge detection faces 42 as it is above-mentioned that
The substantially indeformable moment of sample (at the time of the deformation of detection faces 42 substantially stops).
In addition, the deformation of detection faces 42 substantially stops being not limited to deform complete stopping, it also include following situation: inspection
The deformation in survey face 42 is small to can ignore the degree that impacts to the detection accuracy of pressure pulse wave due to the deformation of detection faces 42.
In step s 6, specifically, the extraction of control unit 12 (is set as detecting with the newest detection moment for being stored in RAM
Moment tn) corresponding strain detecting signal group and be stored in the newest previous detection moment of RAM (when being set as detection
Carve tn-1) corresponding strain detecting signal group.Control unit 12 is calculated in the two strain detecting signal groups and is examined by identical strain
It surveys between the strain detecting signal that element 41 detects (when carving tn and detection when detecting by a strain test element 41
Carve two strain detecting signals detecting respectively of tn-1) difference, and by the summation of calculated difference divided by strain test element
41 sum come calculate difference average value.
The small change in shape for meaning detection faces 42 of the average value of the difference is small.Therefore, it is less than threshold value in the average value of the difference
In the case where, control unit 12 is judged as substantially to be stopped in the deformation of moment tn-1 detection faces 42.In addition, the threshold value is set to
The value that will detect that respectively the difference of pressing force at the time of two strain detecting signal groups is taken into account.
Above-mentioned difference also includes signal difference, and the signal difference is by the pressure that is subject to by the pressing force of detection moment tn from body surface face
Cause with the difference for the pressure being subject to by the pressing force of detection moment tn-1 from body surface face.Therefore, by advance setting the threshold value
For the value bigger than above-mentioned signal difference, at the time of capable of accurately judging that the deformation of detection faces 42 substantially stops.
Alternatively, it is also possible to replace above-mentioned difference, then use two detected at different times by strain test element 41
The ratio of a strain detecting signal.Or, or, the figure that the judgement of control unit 12 is indicated by two strain detecting signal groups respectively
The similar degree of the shape of curve shown in 5 is judged as in the case where similar degree is threshold value or more in moment tn-1 detection faces 42
Deformation substantially stop.
Each strain detecting signal of two strain detecting signal groups for above-mentioned judgement can be the DC component of signal,
It is also possible to the absolute value of signal.In the strain detecting signal detected before deforming the stop timing, hardly comprising adjoint
The AC compounent of beating and generation.Therefore, detection faces 42 can be judged using the either side in DC component and absolute value
Deformation stop at the time of.
If step S6's is judged as YES, control unit 12 by the time of the deformation of detection faces 42 substantially stops that is,
Each strain detecting signal for the strain detecting signal group that deformation stop timing (above-mentioned moment tn-1) is detected by strain transducer 4
It is set as the reference level (step S7) of the strain test element 41 of the output source of above-mentioned each strain detecting signal.
In addition, the variation of the strain generated with beating not yet becomes larger in the deformation stop timing.Therefore, in the deformation
It is substantially only direct current point that each strain detecting signal for the strain detecting signal group that stop timing is detected by strain transducer 4, which becomes,
The signal of amount.
After setting reference level, for first by each strain detecting of strain transducer 4 after deforming the stop timing
The strain detecting signal (hereinafter referred to as the first strain detecting signal) that part 41 detects, control unit 12 are based on to each strain detecting
The reference level that element 41 is set corrects the first strain detecting signal, by after correction the first strain detecting signal and detection
Moment, which establishes, to be associated with and is stored in memory 15 (step S8).
Fig. 6 is an example for the strain detecting signal for indicating that arbitrary element column detect as included by strain transducer 4
Figure.The horizontal axis of (a) of Fig. 6 indicates to constitute the position on the direction X of each strain test element 41 of element column, the longitudinal axis of Fig. 6
Indicate that the strain detecting signal detected by each strain test element 41 (answers variable reference based on the ROM for being stored in control unit 12
Value after value correction).
(a) of Fig. 6 indicates that the arbitrary element column as included by strain transducer 4 detect in the above-mentioned deformation stop timing
The first strain detecting signal an example.
(b) of Fig. 6 indicates the signal after the first strain detecting signal correction shown in (a) of Fig. 6.Pass through step S7 and step
The processing of rapid S8 is all used as zero to be pocessed in the first strain detecting signal that the deformation stop timing obtains.
It by the processing of step S8, is stored in memory 15: by each of strain transducer 4 after deforming the stop timing
Strain test element 41 detects and the inspection of the first strain detecting signal after correcting, the first strain detecting signal after above-mentioned correction
Survey the internal pressure of the air bag 3 of moment and above-mentioned detection moment.
Fig. 7 is to indicate to be detected after deforming the stop timing by arbitrary strain test element 41 and first after correcting answers
Become the figure of the relationship between the internal pressure of the air bag 3 when the detection for detecting signal and the first strain detecting signal.
As described above, detection faces 42 hardly deform after deforming the stop timing.Therefore, until due to strain
Sensor 4 to the pressing in body surface face and Radial artery T starts the pressing initial stage (T1 during in Fig. 7) until conquassation, by
The DC component of the first strain detecting signal after each strain test element 41 is detected and corrected increases phase with the internal pressure of air bag 3
Answer linear variation.
In addition, the Radial artery T after by this period T1 is moderately crushed and becomes close to tonometry state
Period T2, the variation with the DC component of the first strain detecting signal after the increased correction of internal pressure of air bag 3 become smaller.
After step s8, control unit 12 with the multiple detection moments for belonging to period T1 shown in Fig. 7 based on respectively corresponding
Correction after the first strain detecting signal DC component and above-mentioned multiple detection moments each moment air bag 3
Internal pressure, a letter of the relationship between the first strain detecting signal (x) after finding out the internal pressure (y) for indicating air bag 3 and correction
Coefficient a, b of number y=ax+b, and it is stored in RAM (step S9).
For each of the whole strain test element 41 of strain transducer 4, by data horizontally and vertically shown in Fig. 7
It is stored in memory 15.Data of the control unit 12 based on each storage for whole strain test elements 41, for each
Strain test element 41 generates above-mentioned linear function, and associatedly stores with the foundation of strain test element 41.
As an example, straight line F1 shown in Fig. 7 indicates straight shown in the linear function y=ax+b generated as control unit 12
Line.Linear function y=ax+b is change type, for that will be converted based on the first strain detecting signal after the correction of reference level
For pressure signal.
After exporting linear function in step s 9, control unit 12 is based on the output source with the first strain detecting signal
The corresponding linear function of strain test element 41 is converted to the first strain detecting signal after the correction for being stored in memory 15
Pressure signal, and the pressure signal after conversion is stored in memory 15 (step S10).
Be stored with as a result, in memory 15: with after deforming the stop timing by strain transducer 4 each strain detecting member
Part 41 detects and the corresponding pressure signal of the first strain detecting signal after correcting, the pressure signal detection moment and should
The internal pressure of the air bag 3 of detection moment.The pressure signal for being stored in memory 15 is detected by each strain test element 41
Pressure pulse wave.
Pulse wave detection program is transferred to after step S10.
In pulse wave detection program, control unit 12 is based on the boosting in 3 internal pressure of air bag for being stored in memory 15
The pressure signal detected in journey, such as the AC compounent of pressure signal is selected as most preferably for maximum strain test element 41
Element, and the internal pressure that will test the air bag 3 of the detection moment of the pressure signal of the maximum AC compounent is determined as realizing and open
The best pressing force of power measuring state.
Then, the internal pressure of air bag 3 is remained best pressing force by control unit 12, in this state, is based on above-mentioned base
Quasi- level is corrected each strain detecting signal successively detected by best element.Control unit 12 is based on and best element pair
Strain detecting signal after the correction is converted to pressure signal by the above-mentioned linear function answered and generated, and by the pressure after conversion
Force signal is stored in memory 15.
Control unit 12 calculates maximal blood pressure and minimal blood pressure based on the pressure signal for being stored in memory 15 in the above described manner
The biological informations such as equal blood pressure informations, heart rate or Pulse Rate, and calculated biological information is stored in memory 15.
In addition, control unit 12 may not possess biological information computing function.In this case, as long as being formed as follows
Structure: the pressure signal for the memory 15 for being stored in vital information measurement device is sent to electronic equipment, in the electronics
It is calculated in equipment and stores biological information.
As described above, the vital information measurement device of present embodiment judges strain transducer 4 in boost process
At the time of the deformation of detection faces 42 stops, it being set at the moment by the strain detecting signal that each strain test element 41 detects
For benchmark level.I.e. it is capable to by the strain generated in each strain test element 41 is deformed by strain transducer 4
Substantially fixed state detects strain detecting signal as benchmark.Therefore, after the above-mentioned moment, due to strain detecting signal
As the synthesis of the strain detected with pressing force and the strain detected with beating, so can be only to pressure arteries and veins
Wave of fighting is accurately proceed detection.
Turn in addition, the vital information measurement device of present embodiment is generated based on the first strain detecting signal after correction
Formula is changed, which is used to strain detecting signal being converted to pressure signal.In this way, detected due to utilization from the measured
Bio signal generates change type, so can be improved the reliability of the pressure signal after conversion, so as to accurately examining
Measuring pressure pulse wave.
Alternatively, it is also possible to be previously stored be based on during fabrication in the ROM of the control unit 12 of vital information measurement device
From multiple the measured survey and correct after the first strain detecting signal generate for each strain test element 41 turn
Formula is changed, the first strain detecting signal after correction is converted to pressure signal using the change type by control unit 12.According to this knot
Structure, due to the operation for not needing to carry out change type in vital information measurement device, so beginning biological information can be shortened to
Time until measurement, and can be realized the power saving of vital information measurement device.
In addition, vital information measurement device according to the present embodiment, strains for whole included by strain transducer 4
Each generation change type of detecting element 41, will be by arbitrary based on the change type generated to the arbitrary strain test element 41
The first strain detecting signal after strain test element 41 is detected and corrected is converted to pressure signal.In this way, being directed to by application
Each strain test element 41 and different change types carry out the conversion of pressure signal, can be improved the detection of pressure pulse wave
Precision.
In addition, control unit 12 can select (an example from whole strain test elements 41 included by strain transducer 4
Strain test element 41 such as near the center of detection faces 42), based on being belonged to by selected strain test element 41
Multiple detection moments of above-mentioned period T1 detect and correct respectively after the first strain detecting signal and when above-mentioned multiple detections
The internal pressure of the air bag 3 at each moment carved generates the change type converted from strain detecting signal to pressure signal.According to above-mentioned knot
Structure, the operation of the change type of total part as not needing to carry out strain test element 41 included by strain transducer 4, so
The time until starting biological information measurement can be shortened to, and can be realized the power saving of vital information measurement device.
In this case, control unit 12 is based on common in the whole strain test elements 41 generated in the above described manner
One change type, the first strain detecting after each strain test element 41 as included by strain transducer 4 is detected and corrected
Signal is converted to pressure signal.According to this structure, since operand required for the generation of change type can be cut down, so energy
Enough realize the power saving of vital information measurement device.
In the vital information measurement device of present embodiment, air bag 3 and pump 11 can be replaced, then uses internal pressure permanent
It is fixed and can deform air bag, by pressing mechanism that the air bag is pressed to body surface face and the driving for driving the pressing mechanism
Portion.
In this configuration, strain transducer 4 is fixed on the air bag that internal pressure is constant and can deform.Control unit 12 is controlled
Driving portion processed and keep pressing mechanism mobile to body surface surface side.Strain transducer 4 is pressed to body surface face if pressing mechanism is mobile
Pressure, then air bag due to pressing mechanism movement and temporary deformity, the detection faces 42 of strain transducer 4 also deform.Then,
When pressing force increases to a certain extent, the deformation of air bag stops, therefore the deformation of detection faces 42 also stops therefrom.Control
The strain detecting signal detected at the time of the deformation of the detection faces 42 stops being set as reference level by portion 12, is carried out hereafter
Correction.In this configuration, the constant air bag of internal pressure is flexible pressing member.
As described above, following item is disclosed in the present specification.
Disclosed pulse wave detection device includes: flexible strain transducer, has the multiple strains being arranged on substrate
Detecting element；Flexible pressing member presses the strain transducer, and the fixed strain sensing to the body surface face of biology
Device；Driving portion drives the pressing member；Control unit is pressed, the driving portion is controlled, the pressing member is controlled and is answered by described in
Become the pressing force that sensor is pressed to the body surface face；Stop timing judging part is deformed, based on making by the pressing control unit
The strain detecting signal detected respectively in the increased boost process of pressing force by the multiple strain test element, judgement
The deformation stop timing that the deformation of the detection faces of the strain transducer stops；Correction unit, will the deformation stop timing by
The strain detecting signal that the multiple strain test element detects respectively is set as reference level, based on the benchmark electricity
It is flat believed after the deformation stop timing by the first strain detecting that the multiple strain test element detects respectively
Number correction；And pressing creation portion, pressure signal is generated according to the first strain detecting signal after the correction.
In disclosed pulse wave detection device, the pressing creation portion is based on the deformation in the boost process
Multiple moment during between stop timing and the time point that have passed through the predetermined time from the deformation stop timing
Each moment detected by the strain test element and carried out the first strain detecting signal after the correction and the multiple
The pressing force at each moment at moment is generated for the first strain detecting signal after the correction to be converted to pressure
The change type of signal, and it is based on the change type, pressure letter is generated according to the first strain detecting signal after the correction
Number.
In disclosed pulse wave detection device, the multiple strain test element is set to by the pressing creation portion
Pay close attention to element, for each concern element carry out for based on each moment at the multiple moment by the concern element
It detects and carries out the first strain detecting signal after the correction and the pressing force at each moment at the multiple moment will
The first strain detecting signal after carrying out the correction is converted to the processing of the change type of pressure signal, and based on by any
The strain test element detect and carry out the first strain detecting signal after the correction and for described any
Strain test element generate the change type generate pressure signal.
It further include storage medium in disclosed pulse wave detection device, the storage medium will be in the strain sensing
The detection faces of device be it is flat in the state of the respective output signal of the multiple strain test element deposited as a reference value
Storage, the strain detecting signal detected by the strain test element is the signal after being corrected based on a reference value.
In disclosed pulse wave detection device, the multiple strain test element of the strain transducer is arranged in two
Tie up shape.
Disclosed vital information measurement device includes: the pulse wave detection device；And biological information calculation part, it is based on
Biological information is calculated by the pressure signal that the pressing creation portion generates.
Disclosed pulse wave detecting method uses: described using the pressing member of flexible strain transducer and flexibility
Strain transducer has multiple strain test elements for being arranged on substrate, and the pressing member is by the strain transducer to life
The body surface face of object presses, and the fixed strain transducer, and the pulse wave detecting method includes: to make the pressing member by institute
State the step of pressing force increase that strain transducer is pressed to the body surface face；Based in the increased boost process of the pressing force
In the strain detecting signal that is detected respectively by the multiple strain test element, judge the detection faces of the strain transducer
The step of deforming the deformation stop timing stopped；It will be examined respectively in the deformation stop timing by the multiple strain test element
The strain detecting signal measured is set as reference level, based on the reference level carry out the deformation stop timing with
The step of correction of the first strain detecting signal detected respectively by the multiple strain test element afterwards；And according to described
The step of the first strain detecting signal after correction generates pressure signal.
Pressing member of the disclosed pulse wave detection program using flexible strain transducer and flexibility, the strain biography
Sensor has arrangement multiple strain test elements in the same plane, and the pressing member is by the strain transducer to biology
The pressing of body surface face, and the fixed strain transducer, the pulse wave detection program is for making computer execute following steps:
The step of pressing force increase that press the pressing member strain transducer to the body surface face；Based on being pressed described
The strain detecting signal detected respectively in the boost process of pressure increase by the multiple strain test element is answered described in judgement
The step of becoming the deformation stop timing of deformation stopping of the detection faces of sensor；It will be in the deformation stop timing by the multiple
The strain detecting signal that strain test element detects respectively is set as reference level, is carried out based on the reference level
The correction of the first strain detecting signal detected respectively after the deformation stop timing by the multiple strain test element
The step of；And according to after the correction the first strain detecting signal generate pressure signal the step of.
Industrial applicibility
The present invention is especially suitable for sphygmomanometer etc., convenience is high and effective.
More than, using specific embodiment, the present invention is described, but the present invention is not limited to above-mentioned realities
Mode is applied, can be made various changes in the range of not departing from the technical idea of invention disclosed.
The Japanese patent application (Patent 2016-089791) that the application was submitted based on April 27th, 2016, and by its content
It is incorporated herein.
Claims (8)
1. a kind of pulse wave detection device characterized by comprising
Flexible strain transducer has the multiple strain test elements being arranged on substrate；
Flexible pressing member presses the strain transducer, and the fixed strain transducer to the body surface face of biology；
Driving portion drives the pressing member；
Control unit is pressed, the driving portion is controlled, to control the pressing member for the strain transducer to the body surface
The pressing force of face pressing；
Stop timing judging part is deformed, based on making in the increased boost process of the pressing force by the pressing control unit by institute
The strain detecting signal that multiple strain test elements detect respectively is stated, judges that the deformation of the detection faces of the strain transducer stops
The deformation stop timing only；
Correction unit, the strain detecting that will be detected respectively in the deformation stop timing by the multiple strain test element
Signal is set as reference level, examined after the deformation stop timing by the multiple strain based on the reference level
Survey the correction for the first strain detecting signal that element detects respectively；And
Pressing creation portion generates pressure signal according to the first strain detecting signal after the correction.
2. pulse wave detection device according to claim 1, which is characterized in that
The pressing creation portion based in the boost process the deformation stop timing with from the deformation stop timing
Each moment at multiple moment during rising between the time point that have passed through the predetermined time is examined by the strain test element
The first strain detecting signal and the pressing force at each moment at the multiple moment after the correction are surveyed and carry out, it is raw
At the change type for the first strain detecting signal after the correction to be converted to pressure signal, and it is based on the conversion
Formula generates pressure signal according to the first strain detecting signal after the correction.
3. pulse wave detection device according to claim 2, which is characterized in that
The multiple strain test element is set to concern element by the pressing creation portion, based at the multiple moment
Each moment is by the concern element testing and carries out the first strain detecting signal after the correction and the multiple moment
The pressing force at each moment is carried out for each concern element for that will carry out first strain after the correction
Detection signal is converted to the processing of the change type of pressure signal, and is based on being detected and being carried out by the arbitrary strain test element
The first strain detecting signal after the correction and the conversion for the arbitrary strain test element generation
Formula generates pressure signal.
4. pulse wave detection device according to any one of claim 1 to 3, which is characterized in that
Further include storage medium, the storage medium by the detection faces of the strain transducer be it is flat in the state of described in
Multiple respective output signals of strain test element are stored as a reference value,
The strain detecting signal detected by the strain test element is the signal after being corrected based on a reference value.
5. pulse wave detection device according to any one of claim 1 to 4, which is characterized in that
The multiple strain test element of the strain transducer is arranged in two dimension shape.
6. a kind of vital information measurement device characterized by comprising
Pulse wave detection device described in any one of claims 1 to 5；And
Biological information calculation part calculates biological information based on the pressure signal generated by the pressing creation portion.
7. a kind of pulse wave detecting method uses the pressing member of flexible strain transducer and flexibility, the strain sensing
Device has multiple strain test elements for being arranged on substrate, and the pressing member is by the strain transducer to the body surface of biology
Face pressing, and the fixed strain transducer,
The pulse wave detecting method is characterised by comprising:
The step of pressing force increase that press the pressing member strain transducer to the body surface face；
Based on the strain inspection detected respectively in the increased boost process of the pressing force by the multiple strain test element
The step of surveying signal, judging the deformation stop timing that the deformation of the detection faces of the strain transducer stops；
It will be set in the deformation stop timing by the strain detecting signal that the multiple strain test element detects respectively
It is set to reference level, is carried out after the deformation stop timing based on the reference level by the multiple strain test element
The step of correction of the first strain detecting signal detected respectively；And
The step of generating pressure signal according to the first strain detecting signal after the correction.
8. a kind of pulse wave detects program, the pressing member of flexible strain transducer and flexibility, the strain sensing are used
Device has arrangement multiple strain test elements in the same plane, and the pressing member is by the strain transducer to biology
The pressing of body surface face, and the fixed strain transducer,
The pulse wave detection program is characterized in that, for making computer execute following steps:
The step of pressing force increase that press the pressing member strain transducer to the body surface face；
Based on the strain inspection detected respectively in the increased boost process of the pressing force by the multiple strain test element
The step of surveying signal, judging the deformation stop timing that the deformation of the detection faces of the strain transducer stops；
It will be set in the deformation stop timing by the strain detecting signal that the multiple strain test element detects respectively
It is set to reference level, is carried out after the deformation stop timing based on the reference level by the multiple strain test element
The step of correction of the first strain detecting signal detected respectively；And
The step of generating pressure signal according to the first strain detecting signal after the correction.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2016-089791 | 2016-04-27 | ||
| JP2016089791A JP6651971B2 (en) | 2016-04-27 | 2016-04-27 | Pulse wave detecting device, biological information measuring device, pulse wave detecting method, and pulse wave detecting program |
| PCT/JP2017/015751 WO2017188092A1 (en) | 2016-04-27 | 2017-04-19 | Pulse wave detection device, biological information measurement device, pulse wave detection method, and pulse wave detection program |
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| CN109069036A true CN109069036A (en) | 2018-12-21 |
| CN109069036B CN109069036B (en) | 2021-08-10 |
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| CN201780026138.0A Active CN109069036B (en) | 2016-04-27 | 2017-04-19 | Pulse wave detection device, biological information measurement device, pulse wave detection method, and storage medium |
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| US (1) | US11141074B2 (en) |
| EP (1) | EP3449819B1 (en) |
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| KR20200005445A (en) * | 2018-07-06 | 2020-01-15 | 삼성전자주식회사 | Apparatus and method for measuring bio-information |
| KR102655675B1 (en) * | 2018-09-21 | 2024-04-05 | 삼성전자주식회사 | Apparatus and method for estimating bio-information |
| JP6472153B1 (en) * | 2018-11-08 | 2019-02-20 | 兆奇 胡 | Health condition evaluation system by pulse measurement and its operation method |
| WO2020231559A1 (en) * | 2019-05-10 | 2020-11-19 | Massachusetts Institute Of Technology | Dry double-sided material for adhesion of wet tissues and devices |
| CN110897616A (en) * | 2019-12-05 | 2020-03-24 | 中国科学院微电子研究所 | Customia pulse position detection device and method |
| WO2022249717A1 (en) * | 2021-05-26 | 2022-12-01 | ミネベアミツミ株式会社 | Vital sensor |
| CN114190909A (en) * | 2021-12-01 | 2022-03-18 | 上海平脉科技有限公司 | Pulse wave detection device and control method thereof |
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| EP3449819B1 (en) | 2021-08-25 |
| US20190046050A1 (en) | 2019-02-14 |
| JP6651971B2 (en) | 2020-02-19 |
| US11141074B2 (en) | 2021-10-12 |
| WO2017188092A1 (en) | 2017-11-02 |
| CN109069036B (en) | 2021-08-10 |
| JP2017196192A (en) | 2017-11-02 |
| EP3449819A4 (en) | 2019-12-04 |
| EP3449819A1 (en) | 2019-03-06 |
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