CN109044382B - Bladder urine volume monitoring system and monitoring method thereof - Google Patents
Bladder urine volume monitoring system and monitoring method thereof Download PDFInfo
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- CN109044382B CN109044382B CN201810668429.6A CN201810668429A CN109044382B CN 109044382 B CN109044382 B CN 109044382B CN 201810668429 A CN201810668429 A CN 201810668429A CN 109044382 B CN109044382 B CN 109044382B
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Abstract
The invention relates to the technical field of medical instruments, in particular to a bladder urine volume monitoring system and a monitoring method thereof. When urine in the bladder slowly increases, the force monitoring device detects the force acting on the bladder at a certain moment and generates a corresponding analog voltage signal, and the analog voltage signal is transmitted to the controller; the controller carries out noise reduction, filtering and analog-to-digital conversion processing on the analog voltage signal, the obtained digital voltage signal is sent to a data receiving device outside the body from the inside of the body through the wireless transmitting device, the data receiving device transmits the received digital voltage signal to a terminal, and the urine volume value of the bladder is obtained through calculation of the terminal. The invention adopts the distribution arrangement of a plurality of force sensors, overcomes the defect of inaccurate measurement caused by the change of urine position due to the change of human body posture when a single sensor is implanted; and the charging device arranged in the body and the electric energy transmitting device arranged outside the body form a power supply system of the monitoring system, so that the problem of frequently replacing the built-in battery in the body is avoided.
Description
Technical Field
The invention relates to the technical field of medical instruments, in particular to a bladder urine volume monitoring system and a monitoring method thereof.
Background
Clinically, the weakness and paralysis of detrusor muscle of bladder caused by urethra stenosis, tumor and other diseases, congenital malformation, injury pathological changes, tumor and inflammation pathological changes and the like can cause bladder over-expansion, internal pressure is increased, urine flow is forced to overflow, and therefore complications such as urinary system infection and the like are induced, the life quality of a patient is seriously affected, and even the life health of the patient is damaged. If the patient can sense the change of the bladder urine by himself, corresponding auxiliary urination measures are taken before the bladder urine volume reaches the bearable maximum volume, such as intermittent catheterization or bladder urination stimulation, the pain of the patient can be relieved, and the life quality of the patient can be improved.
The monitoring research on bladder urine capacity at home and abroad is numerous, and mainly comprises: (1) a bladder capacity measuring system using an electrical impedance method. The system mainly comprises three parts, namely an electrode, a transmitter and a receiver. The resistance between two electrodes fixed on the opposite position on the bladder wall is increased along with the increase of urine volume in the bladder, the transmitter transmits the signal of the resistance change to a receiver outside the body, and the receiver detects the urine volume of the bladder; (2) bladder pressure detection system: the in vivo pressure detection module is composed of a voltage stabilizing circuit, a pressure sensor and the like, and the in vivo pressure detection is powered wirelessly by the in vitro controller. However, the former detection results are affected by various factors such as urine conductivity, ambient temperature, electrode placement, bladder blood flow, fibrosis around the electrode, sustained current damage to tissue, and electrode dislocation; the latter is because not adopting built-in rechargeable battery power supply, can't make pressure detection module break away from external power supply real-time detection bladder urine volume and the pressure sensor who uses need implant bladder inside and carry out pressure detection, contacts with urine, easily causes the infection.
Disclosure of Invention
The invention aims to overcome the defects of the prior art, provides a bladder urine volume monitoring system and a monitoring method thereof, can overcome the defect of inaccurate measurement caused by urine position change caused by human posture change of a single sensor, and can avoid urinary system infection caused by direct contact of an in-vivo device and urine in a bladder.
In order to solve the technical problems, the invention adopts the technical scheme that:
the bladder urine volume monitoring system comprises an in-vivo device and an in-vitro device which are connected through signals, wherein the in-vivo device is arranged in the outer abdominal wall, and the in-vitro device is arranged outside the outer abdominal wall; a bladder support is encircled outside the bladder and is fixed on the pubis, and the bladder support is provided with a through hole which can accommodate the urethra and the ureter to pass through; the in-vivo device comprises a charging device arranged in a waterproof sealed container and a force monitoring device arranged on the inner side of the bladder support, a wireless transmitting device and a controller for realizing analog voltage signal noise reduction, filtering and analog-to-digital conversion are also arranged in the waterproof sealed container, the wireless transmitting device is connected to the output end of the controller, and the force monitoring device and the charging device are both connected to the input end of the controller; the in-vitro device comprises an electric energy transmitting device and a data receiving device, the electric energy transmitting device is wirelessly connected with the charging device, the data receiving device is wirelessly connected with the wireless transmitting device, and the data receiving device is connected with a terminal used for calculating the urine volume value of the bladder.
According to the bladder urine volume monitoring system, when urine in the bladder slowly increases, the force monitoring device detects force acting on the bladder at a certain moment and generates a corresponding analog voltage signal, and the analog voltage signal is transmitted to the controller; the controller carries out noise reduction, filtering and analog-to-digital conversion processing on the analog voltage signal, the obtained digital voltage signal is sent to a data receiving device outside the body from the inside of the body through the wireless transmitting device, the data receiving device transmits the received digital voltage signal to a terminal, and the urine volume value of the bladder is obtained through calculation of the terminal. The charging device arranged in the body and the electric energy transmitting device arranged outside the body form a power supply system, so that electric energy is provided for the whole monitoring system, and the problem of frequently replacing a built-in battery in the body is avoided; and the in-vivo device is mostly arranged in the sealed waterproof container, thereby avoiding direct contact with body fluid and avoiding the risk of liquid leakage.
Furthermore, the force monitoring device comprises a fixing strip and a plurality of force sensors surrounding the fixing strip, the fixing strip surrounds the inner side of the bladder support, and the force sensors are connected in parallel. The plurality of force sensors are distributed, so that the defect that the measurement is inaccurate due to the change of urine positions caused by the change of human postures of the implanted single force sensor can be overcome.
Furthermore, the electric energy transmitting device comprises a high-frequency power supply, a transmitting chip and a transmitting coil which are connected in sequence, wherein the transmitting coil is of a disc-shaped structure formed by winding a plurality of turns of conductive metal coils. The high-frequency power supply, the transmitting chip and the transmitting coil form an external transmitting circuit to charge the internal rechargeable battery.
Further, charging device is including the receiving coil, charging chip and the rechargeable battery who passes through wire series connection in order, receiving coil is the disk structure that is formed by the winding of multiturn conductive metal coil, receiving coil and transmitting coil magnetism are connected. The receiving coil, the charging chip and the charging battery form an internal chargeable power supply and provide electric energy for the monitoring circuit in the body.
Further, the distance between the receiving coil and the transmitting coil is not more than 90 cm. Because the magnetic field between the receiving coil and the transmitting coil has distance limitation, the distance between the receiving coil and the transmitting coil is limited to be less than 90 cm. It should be noted that this is only preferred as the present invention, and the distance between the two can be increased correspondingly as the technical problem is overcome.
Further, the transmitting chip is provided with an indicator light for indicating whether the rechargeable battery is fully charged. When the electric energy transmitting device is close to the charging device to charge the charging device, the indicator lamp displays red to indicate that the charging battery is in a charging state; when the rechargeable battery is fully charged, the indicator light turns green; whether the rechargeable battery is in a power-off state or a power-full state can be observed through the indicating lamp, and the operation is visual and clear.
Further, the bladder support is a bowl-shaped net structure made of medical alloy materials, and the sealed waterproof container is a closed structure made of medical alloy materials. The bladder support and the sealed waterproof container are made of alloy which is compatible with the human body biology, so that the weight is light, and no rejection reaction exists.
Further, a neural network model is established on the terminal, the neural network model comprises an input layer, a hidden layer and an output layer which are connected in sequence, the input of the input layer is a digital voltage signal generated by the force sensor, and the output of the output layer is a bladder urine volume value. The neural network is adopted to calculate the bladder urine volume value, the calculation is accurate, and the calculation speed is high.
The invention also provides a monitoring method of the bladder urine capacity monitoring system, which comprises the following steps:
s1, creating a neural network model and performing offline training on the neural network model;
s2, when urine in bladder increases slowly, each force sensor detects the force acted on it at a certain moment and generates corresponding analog voltage signal, the analog voltage signal is transmitted to the controller;
s3, the controller makes noise reduction, filtering and A/D conversion processing to the analog voltage signal in step S2, and sends the obtained digital voltage signal from the inside of the body to the data receiving device outside the body by the wireless transmitting device;
s4, the data receiving device transmits the received digital voltage signals to the terminal, and the terminal converts the acquired voltage signals output by each force sensor into input values;
and S5, inputting the input value in the step S4 into the neural network model trained offline in the step S1, and calculating to obtain the bladder urine volume value.
According to the bladder urine capacity monitoring method, when urine in the bladder slowly increases, the force sensors respectively detect the force acting on the bladder at a certain moment and generate corresponding analog voltage signals, the controller performs noise reduction, filtering and analog-to-digital conversion on the analog voltage signals, then the obtained digital voltage signals are sent to a data receiving device outside the body from the inside of the body through the wireless transmitting device, and the wireless transmitting device transmits the signals to the terminal. And the terminal converts the acquired voltage signals output by each force sensor into input values, and inputs the input values into the neural network model to obtain the volume value of the urine in the bladder. The invention has simple structure, can monitor the bladder urine capacity of the patient in real time through the terminal, and brings life convenience for the patient with the dysuresia perception function.
Preferably, the offline training of the neural network model in step S1 includes the following steps:
s11, initializing the weight and bias value of the neural network model;
s12, normalizing the digital voltage signal value output by each force sensor at a certain moment to be used as a training sample, and inputting the training sample to an input layer of the neural network model;
s13, carrying out neural network training, and calculating the output of neural units of the hidden layer and the output layer;
s14, calculating the deviation between the output value of the output layer and the measured value of the urine volume of the bladder in the step S13, and if the deviation meets the set deviation requirement, ending the training; if the deviation requirement is not satisfied, the weight and the offset value are corrected and the training is continued by returning to step S13.
Compared with the prior art, the invention has the beneficial effects that:
(1) the invention enables the patient to monitor the volume value of the bladder urine in real time through the terminal, and brings life convenience to the patient with the dysuresia perception function.
(2) The distribution of a plurality of force sensors is adopted, and the defect that the measurement is inaccurate due to the change of urine position caused by the change of human body posture when a single sensor is implanted is overcome.
(3) The external electric energy transmitting device and the internal charging device form a power supply system of the whole monitoring system, and the power supply system can be charged repeatedly to supply power to the monitoring circuit, so that the problem of frequently replacing an internal battery is avoided.
(4) The charging device, the controller and the wireless transmitting device in the body are arranged in the waterproof sealed container and are not in contact with bladder urine, urinary system infection can be avoided, and the risk of leakage is also avoided.
(5) The bladder support and the sealed waterproof container are made of alloy which is compatible with the human body biology, so that the weight is light, and no rejection reaction exists.
Drawings
Fig. 1 is a schematic structural diagram of a bladder urine volume monitoring system.
Fig. 2 is a schematic diagram of bladder urine volume monitoring.
Fig. 3 is a schematic structural diagram of a neural network model.
FIG. 4 is a flow chart of training of a neural network model.
In the drawings: 1-bladder; 2-pubic bone; 3-waterproof sealed container; 4-a receiving coil; 5-a charging chip; 6-a rechargeable battery; 7-a controller; 8-a wireless transmitting device; 9-a wire; 10-a force sensor; 11-the urethra; 12-a fixing strip; 13-ureter; 14-bladder stents; 15-a transmitting coil; 16-an indicator light; 17-an emitting chip; 18-a high frequency power supply; 19-a data receiving device; 20-a terminal; 21-external abdominal wall.
Detailed Description
The present invention will be further described with reference to the following embodiments. Wherein the showings are for the purpose of illustration only and are shown by way of illustration only and not in actual form, and are not to be construed as limiting the present patent; to better illustrate the embodiments of the present invention, some parts of the drawings may be omitted, enlarged or reduced, and do not represent the size of an actual product; it will be understood by those skilled in the art that certain well-known structures in the drawings and descriptions thereof may be omitted.
The same or similar reference numerals in the drawings of the embodiments of the present invention correspond to the same or similar components; in the description of the present invention, it should be understood that if there is an orientation or positional relationship indicated by the terms "upper", "lower", "left", "right", etc. based on the orientation or positional relationship shown in the drawings, it is only for convenience of describing the present invention and simplifying the description, but it is not intended to indicate or imply that the referred device or element must have a specific orientation, be constructed in a specific orientation, and be operated, and therefore, the terms describing the positional relationship in the drawings are only used for illustrative purposes and are not to be construed as limiting the present patent, and the specific meaning of the terms may be understood by those skilled in the art according to specific circumstances.
Example 1
Fig. 1 to 3 show an embodiment of the bladder urine volume monitoring system according to the present invention, which includes an in-vivo device and an in-vitro device connected by signals, wherein the in-vivo device is disposed inside the external abdominal wall 21, and the in-vitro device is disposed outside the external abdominal wall 21; a bladder support 14 is encircled outside the bladder 1, the bladder support 14 is fixed on the pubis 2, and the bladder support 14 is provided with a through hole which can accommodate the urethra 11 and the ureter 13 to pass through; the in-vivo device comprises a charging device arranged in the waterproof sealed container 3 and a force monitoring device arranged on the inner side of the bladder support 14, a wireless transmitting device 8 and a controller 7 used for realizing noise reduction, filtering and analog-to-digital conversion of an analog voltage signal are also arranged in the waterproof sealed container 3, the wireless transmitting device 8 is connected to the output end of the controller 7, and the force monitoring device and the charging device are both connected to the input end of the controller 7; the in vitro device comprises an electric energy transmitting device and a data receiving device, the electric energy transmitting device is wirelessly connected with the charging device, the data receiving device is wirelessly connected with the wireless transmitting device, and the data receiving device is connected with a terminal 20 used for calculating the urine volume value of the bladder. The force monitoring device of the embodiment comprises a fixing strip 12 and N (N is more than or equal to 3) force sensors 10 which are arranged on the fixing strip 12 in a surrounding mode, wherein the fixing strip 12 is arranged on the inner side of a bladder support 14 in a surrounding mode, the N force sensors 10 are connected in parallel, and a lead 9 is connected between the force sensors 10 and a controller 7. The N force sensors 10 are distributed, so that the defect that the measurement is inaccurate due to the change of urine positions caused by the change of human postures of the implanted single force sensor can be overcome.
As shown in fig. 2, in this embodiment, when the urine in the bladder slowly increases, the force monitoring device detects the force acting on it at a certain moment and generates a corresponding analog voltage signal, and the analog voltage signal is transmitted to the controller 7; the controller 7 performs noise reduction, filtering and analog-to-digital conversion processing on the analog voltage signal, sends the obtained digital voltage signal to a data receiving device 19 outside the body from the inside of the body through a wireless transmitting device 8, the data receiving device 19 transmits the received digital voltage signal to a terminal 20, and the urine volume value of the bladder is obtained through calculation through the terminal 20.
Specifically, the electric energy transmitting device comprises a high-frequency power supply 18, a transmitting chip 17 and a transmitting coil 15 which are connected in sequence, wherein the transmitting coil 15 is a disc-shaped structure formed by winding a plurality of turns of conductive metal coils. The charging device comprises a receiving coil 4, a charging chip 5 and a charging battery 6 which are connected in series through a conducting wire in sequence, wherein the receiving coil 4 is of a disc-shaped structure formed by winding a plurality of turns of conductive metal coils, and the receiving coil 4 is magnetically connected with a transmitting coil 15. The distance between the receiving coil 4 and the transmitting coil 15 is not more than 90 cm. Wherein, the high-frequency power supply 18, the transmitting chip 17 and the transmitting coil 15 form an external transmitting circuit to charge the internal rechargeable battery; the receiving coil 4, the charging chip 5 and the charging battery 6 form an in-vivo chargeable power supply for providing electric energy for an in-vivo monitoring circuit. In addition, the transmitting chip 17 is provided with an indicator lamp for indicating whether the rechargeable battery is fully charged. When the electric energy emitting device is close to the charging device to charge the charging device, the indicator light 16 displays red color, which indicates that the rechargeable battery 6 is in a charging state; when the rechargeable battery 6 is fully charged, the indicator lamp turns green.
The bladder support 14 in this embodiment is a bowl-shaped net structure made of medical alloy material, and the sealed waterproof container is a closed structure made of medical alloy material, and has good biocompatibility with human body, light weight and no rejection reaction.
In addition, as shown in fig. 3, the terminal 20 in this embodiment creates a neural network model, the neural network model includes an input layer, a hidden layer and an output layer, which are connected in sequence, the input of the input layer is a digital voltage signal generated by the force sensor, and the output of the output layer is a bladder urine capacity value.
Example two
The embodiment is an embodiment of a method for monitoring bladder urine capacity, and the method comprises the following steps:
s1, creating a neural network model and performing offline training on the neural network model;
s2, when urine in bladder slowly increases, each force sensor 10 respectively detects the force acted on it at a certain moment and generates corresponding analog voltage signal, and the analog voltage signal is transmitted to the controller 7;
s3, the controller 7 carries out noise reduction, filtering and analog-to-digital conversion processing on the analog voltage signal in the step S2, and sends the obtained digital voltage signal from the inside of the body to the data receiving device 19 outside the body through the wireless transmitting device 8;
s4, the data receiving device 19 transmits the received digital voltage signals to the terminal 20, and the terminal 20 converts the acquired voltage signals output by the force sensors 10 into input values;
and S5, inputting the input value in the step S4 into the neural network model trained offline in the step S1, and calculating to obtain the volume value of the urine in the bladder.
As shown in fig. 4, the offline training of the neural network model in step S1 includes the following steps:
s11, initializing the weight and bias value of the neural network model;
s12, normalizing the digital voltage signal value output by each force sensor at a certain moment to be used as a training sample, and inputting the training sample to an input layer of the neural network model;
s13, carrying out neural network training, and calculating the output of neural units of the hidden layer and the output layer;
s14, calculating the deviation between the output value of the output layer and the measured value of the urine volume of the bladder in the step S13, and if the deviation meets the set deviation requirement, ending the training; if the deviation requirement is not satisfied, the weight and the offset value are corrected and the training is continued by returning to step S13.
In step S5, the method for calculating the bladder urine volume value includes: the digital voltage signals obtained by noise reduction, filtering and analog-to-digital conversion of N voltage values 1, 2 and 3 … … N acquired by N sensors at a certain moment are used as input values of a neural network model trained offline, and the volume value of urine in the bladder is calculated and output by the neural network model trained offline.
It should be understood that the above-described embodiments of the present invention are merely examples for clearly illustrating the present invention, and are not intended to limit the embodiments of the present invention. Other variations and modifications will be apparent to persons skilled in the art in light of the above description. And are neither required nor exhaustive of all embodiments. Any modification, equivalent replacement, and improvement made within the spirit and principle of the present invention should be included in the protection scope of the claims of the present invention.
Claims (8)
1. The bladder urine volume monitoring system is characterized by comprising an in-vivo device and an in-vitro device which are connected through signals, wherein the in-vivo device is arranged in the external abdominal wall, and the in-vitro device is arranged outside the external abdominal wall; a bladder support is encircled outside the bladder and is fixed on the pubis, and the bladder support is provided with a through hole which can accommodate the urethra and the ureter to pass through; the in-vivo device comprises a charging device arranged in a waterproof sealed container and a force monitoring device arranged on the inner side of the bladder support, a wireless transmitting device and a controller for realizing analog voltage signal noise reduction, filtering and analog-to-digital conversion are also arranged in the waterproof sealed container, the wireless transmitting device is connected to the output end of the controller, and the force monitoring device and the charging device are both connected to the input end of the controller; the force monitoring device comprises a fixing strip and a plurality of force sensors which surround the fixing strip, the fixing strip surrounds the inner side of the bladder support, and the force sensors are connected in parallel; the in-vitro device comprises an electric energy transmitting device and a data receiving device, the electric energy transmitting device is wirelessly connected with the charging device, the data receiving device is wirelessly connected with the wireless transmitting device, and the data receiving device is connected with a terminal used for calculating the urine volume value of the bladder.
2. The bladder urine volume monitoring system of claim 1, wherein the power transmitter comprises a high frequency power source, a transmitter chip and a transmitter coil connected in sequence, and the transmitter coil is a disc-shaped structure formed by winding a plurality of turns of conductive metal coils.
3. The bladder urine volume monitoring system of claim 2, wherein the charging device comprises a receiving coil, a charging chip and a charging battery which are connected in series by a conducting wire in sequence, the receiving coil is a disc-shaped structure formed by winding a plurality of turns of conductive metal coils, and the receiving coil is magnetically connected with the transmitting coil.
4. The bladder urine volume monitoring system according to claim 3, wherein the distance between the receiving coil and the transmitting coil is no more than 90 cm.
5. The bladder urine volume monitoring system according to claim 4, wherein the transmitting chip is provided with an indicator light for indicating whether the rechargeable battery is fully charged.
6. The bladder urine volume monitoring system according to claim 1, wherein the bladder support is a bowl-shaped mesh structure made of medical alloy material, and the sealed waterproof container is a closed structure made of medical alloy material.
7. The bladder urine volume monitoring system according to claim 1, wherein the terminal is created with a neural network model, the neural network model comprises an input layer, a hidden layer and an output layer which are connected in sequence, the input of the input layer is a digital voltage signal generated by the force sensor, and the output of the output layer is a bladder urine volume value.
8. A monitoring method of a bladder urine volume monitoring system according to any one of claims 1 to 7, comprising the steps of:
s1, creating a neural network model and performing offline training on the neural network model;
s2, when urine in the bladder slowly increases, each force sensor respectively detects force acting on the force sensor at a certain moment and generates a corresponding analog voltage signal, and the analog voltage signals are transmitted to the controller;
s3, the controller performs noise reduction, filtering and analog-to-digital conversion processing on the analog voltage signal in the step S2, and sends the obtained digital voltage signal to a data receiving device outside the body from the inside of the body through a wireless transmitting device;
s4, the data receiving device transmits the received digital voltage signals to a terminal, and the terminal converts the acquired voltage signals output by each force sensor into input values;
s5, inputting the input value in the step S4 into the neural network model trained offline in the step S1 to calculate to obtain the bladder urine volume value;
wherein, the offline training of the neural network model in the step S1 includes the following steps:
s11, initializing a weight value and a bias value of the neural network model;
s12, normalizing the digital voltage signal value output by each force sensor at a certain moment to be used as a training sample, and inputting the training sample to an input layer of a neural network model;
s13, carrying out neural network training, and calculating the output of neural units of a hidden layer and an output layer;
s14, calculating the deviation between the output value of the output layer in the step S13 and the measured value of the urine capacity of the bladder, and finishing training if the deviation meets the set deviation requirement; if the deviation requirement is not satisfied, the weight and the offset value are corrected and the training is continued by returning to step S13.
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| US9750591B1 (en) * | 2016-07-29 | 2017-09-05 | Sam Sultan | Systems and methods for assisting patients in emptying their bladder efficiently |
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| CN1874048A (en) * | 2006-04-28 | 2006-12-06 | 清华大学 | Wireless charging device through skin in use for implantation type medical treatment instrument |
| CN103892820A (en) * | 2014-03-05 | 2014-07-02 | 首都医科大学 | Implantable wireless passive bladder pressure detection system |
| CN108024769A (en) * | 2015-07-27 | 2018-05-11 | 中央兰开夏大学 | Method and apparatus for estimating bladder condition |
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