CN109044248A - Three-dimensional Photoacoustic endoscope and its imaging method in bending cavity based on snake bone deflecting - Google Patents
Three-dimensional Photoacoustic endoscope and its imaging method in bending cavity based on snake bone deflecting Download PDFInfo
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- CN109044248A CN109044248A CN201810695072.0A CN201810695072A CN109044248A CN 109044248 A CN109044248 A CN 109044248A CN 201810695072 A CN201810695072 A CN 201810695072A CN 109044248 A CN109044248 A CN 109044248A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B1/00—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
- A61B1/06—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor with illuminating arrangements
- A61B1/0661—Endoscope light sources
- A61B1/0684—Endoscope light sources using light emitting diodes [LED]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B1/00—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
- A61B1/005—Flexible endoscopes
- A61B1/0051—Flexible endoscopes with controlled bending of insertion part
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B1/00—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
- A61B1/04—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor combined with photographic or television appliances
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B1/00—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
- A61B1/06—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor with illuminating arrangements
- A61B1/07—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor with illuminating arrangements using light-conductive means, e.g. optical fibres
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/0093—Detecting, measuring or recording by applying one single type of energy and measuring its conversion into another type of energy
- A61B5/0095—Detecting, measuring or recording by applying one single type of energy and measuring its conversion into another type of energy by applying light and detecting acoustic waves, i.e. photoacoustic measurements
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
- A61B8/12—Diagnosis using ultrasonic, sonic or infrasonic waves in body cavities or body tracts, e.g. by using catheters
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Abstract
The invention discloses Photoacoustic endoscope three-dimensional in a kind of bending cavity based on snake bone deflecting and imaging methods.The endoscope includes integral scanning head, snake cyrtosis portion, insertion hose, 3-D scanning part, control handle and junction portion.Optical acoustic scanning probe and optical camera are integrated in integral scanning head, optoacoustic probe realizes that mechanical ring is swept and withdrawn by 3-D scanning part, snake cyrtosis portion connecting integration probe and insertion hose, the four-way bending of integral scanning head is realized under the adjusting of control handle, junction portion connects pulse laser and host.This method realizes the three-dimensional photoacoustic imaging in the bending cavity under video image guidance using the deflecting of snake bone.The present invention is based on three-dimensional photoacoustic imaging methods in the bending cavity of snake bone deflecting and its endoscope to combine high-res photoacoustic imaging and fine definition optical imagery, and three-dimensional structure, function and the molecular image of bending cavity inner surface high clear video image and cavity tissue are obtained using snake bone deflecting.
Description
Technical field
The invention belongs to medical endoscope technical field, it is related to three-dimensional optoacoustic in a kind of bending cavity based on snake bone deflecting
Endoscope and its imaging method.
Background technique
Medical endoscope be to body cavity tissue check, the instrument of diagnosing and treating.Existing endoscope is main
There are optical video endoscope, ultrasonic endoscopic and optical coherence tomography endoscope.Optical video endoscope can provide cavity group
The high-definition camera on surface is knitted, but can not observe the fault structure of cavity tissue, limits its medical diagnosis on disease to a certain extent
Ability；The depth structure information of the available cavity tissue of ultrasonic endoscopic, but its image contrast is lower, can not reflect early stage
Lesion；Optical coherence tomography endoscope can be imaged cavity cross-section by focus on light beam, and have very high resolution ratio,
But its imaging depth is only 1 millimeter or so, cannot fully meet clinical diagnosis demand, and is unable to get blood oxygen saturation, oxo
The physiological parameters such as thank.
Photoacoustic imaging is the new bio medical imaging procedure of a kind of non-invasive and unionized formula that developed recently gets up,
The advantages of optical imagery and ultrasonic imaging, is combined.It on the one hand, is super for the signal of reconstruction image in photoacoustic imaging
Acoustical signal, biological tissue will compare low 2~3 orders of magnitude of scattering of optical signal to the scattering of ultrasonic signal, therefore it can be mentioned
For deeper imaging depth and higher spatial resolution；On the other hand, photoacoustic imaging is according to different tissues to visible light, close red
Outer the light even selective absorbing of microwave band electromagnetic wave are irradiated tissue using the laser pulse of specific wavelength, to arteries and veins
Rush energy in biological tissues absorption distribution be imaged, imaging is the luminous energy being " absorbed ", thus compared to it is pure ultrasound at
Picture, photoacoustic imaging have high organism optical contrast.
Optoacoustic endoscopy imaging technology is the knot of photoacoustic imaging technology and Endoscopy as a kind of novel imaging method
It closes, for the detection of cavity tissue, provides the imaging technique of high spatial resolution and high contrast in tissue, merged and interior peeped sound
Learn the advantage with optical imagery.Optical fiber, ultrasonic transducer, reflecting mirror and lenticule are integrated into the spy of scope front end by Photoacoustic endoscope
In head, by rotating optoacoustic endoscopy scanning probe, realizes circumference or spiral excitation and acquisition, reconstruct cavity by inversion algorithm
The optical absorption distributed image of tissue.
102078179 A of patent No. CN proposes a kind of three-dimensional electronic colonoscope system, passes through more ccd array
Module carries out the 3 D stereo scanning shoot of straight line and rotation to colon, shows panorama three-dimensional image, and carry out to colon
Stereopsis reconstruct, but the invention can only obtain colon road dimensional surface information, can not obtain the fault information of intestinal tissue；Specially
103462644 A of benefit CN proposes a kind of Photoacoustic endoscope, which absorbs pulse by detection destination organization and swash
The ultrasonic signal generated after light, is analyzed and processed imaging, the photoacoustic image of available higher contrast, but the invention
It is not bound with reversible bending section, and without optical camera, therefore cannot can not intuitively observe chamber individually by bending cavity
The high-definition image in body surface face, is unfavorable for diagnosis.
In conclusion needing to design a kind of integrated optical acousto-optics endoscope system applied to human body bending cavity tissue
System.The present invention by high definition optical camera and the endoscope of high parsing being integrated in one of photoacoustic imaging, is become for the first time using snake bone
To three-dimensional structure, function and the molecular image for obtaining bending cavity inner surface high clear video image and cavity tissue.
Summary of the invention
The shortcomings that it is a primary object of the present invention to overcome the prior art and deficiency, provide a kind of based on the curved of snake bone deflecting
Three-dimensional Photoacoustic endoscope in bent cavity, the present invention by optical acoustic scanning probe in the epitheca of being integrated in one of optical camera,
More conducively detect；Based on bending snake bone deflecting cephalic par, three-dimensional optical acoustic scanning is realized using rotating electric machine and linear motor, can be obtained
The high-res three-dimensional light sound shadow picture and the full sight field video picture of fine definition of cavity tissue must be bent.
Another object of the present invention is to provide a kind of to be bent three-dimensional Photoacoustic endoscope in cavity based on snake bone deflecting
Imaging method.
In order to reach above-mentioned first purpose, the invention adopts the following technical scheme:
Three-dimensional Photoacoustic endoscope in bending cavity based on snake bone deflecting, comprising: integral scanning head, snake cyrtosis portion,
It is inserted into hose, 3-D scanning part, control handle and junction portion；
The integral scanning head includes optical acoustic scanning probe, micro-optical camera, integrated epitheca, and the optoacoustic is swept
It retouches probe to do rotation in integrated epitheca and withdraw movement, the micro-optical camera is fixed in integrated epitheca；
Snake cyrtosis portion connecting integration probe and insertion hose, are realized by operating control handle to integration
Probe upper and lower, left and right four-way is adjusted, and snake cyrtosis portion is constituted by being bent snake bone, is bent snake bone one end connecting integration
The rear end of scanning head, the front end of other end connection insertion hose；
The front end of the 3-D scanning part is connected with insertion hose, and rear end is connected with control handle, the 3-D scanning
Part includes rotating electric machine, linear motor, conducting slip ring, the first synchronizing wheel, the second synchronizing wheel, synchronous belt, connection structure and outer
Shell, the linear motor control rotating electric machine generate linear motion, rotating electric machine fuselage and conducting slip ring shell and pass through connection knot
Structure is fixed together, and conducting slip ring inner hollow, spin motor shaft is connected and fixed with the first synchronizing wheel, and the second synchronizing wheel is from conduction
Slip ring hollow hole passes through, and fixes with rotor-end, and the first synchronizing wheel and the second synchronizing wheel are by toothed belt transmission, thus by electric rotating
The torque transfer of arbor gives conductive sliding ring rotor end, and the second synchronizing wheel is popped one's head in optical acoustic scanning and connect by torsion coil, passed through
Torsion coil transmits torque to optical acoustic scanning probe, so that optical acoustic scanning probe is rotated movement, while moving along a straight line,
Three-dimensional optoacoustic ring is realized to sweep.
The optical acoustic scanning is popped one's head in outer diameter 5-6mm as a preferred technical solution, internal light channel structure it is axially distributed from
Rising at head end is respectively metallic-membrane plating reflector, lenticule/lenticule group and optical fiber, and the metallic-membrane plating reflector plates high-reflecting film, reflectivity
Greater than 99%, reflection surface inclination is 35 degree；The lenticule/lenticule group diameter 1-3mm has to from the laser beam of fiber exit
There are collimation or focussing force；The optical fiber is fixed with micro- bearing inner wall, and micro- bearing outer wall is fixed with optical acoustic scanning inner probe wall, when
Optical fiber can be kept not rotate when optical acoustic scanning probe rotation；The front end of the metallic-membrane plating reflector is additionally provided with ultrasonic transducer, from
The laser beam of fiber exit successively through lenticule/lenticule group and metallic-membrane plating reflector be radiated at the ultrasonic transducer just on
Side.
The micro-optical camera head diameter 2-4mm as a preferred technical solution, depth of field 3-100mm, field angle
120 degree, built-in LED illumination, illumination intensity can be adjusted by host panel.
The integrated epitheca diameter 11-13mm as a preferred technical solution, there are the first circular through hole, second in inside
Circular through hole and two fan-shaped pylones, the first circular through hole are that optoacoustic ring sweeps probe channel, and the second circular through hole micro-optical is taken the photograph
As head channel, two fan-shaped pylones are located at the two sides of the first circular through hole, and for filling the water and being vented, fan-shaped pylone end is
Hollow circuit cylinder connector, for connecting water injection pipe；The integration epitheca end is equipped with the first cylindrical piece, difference in the first cylindrical piece
Torsion coil housing hose fixation hole, water filling pipe through-hole and video line three-way hole, the torsion coil housing hose is provided with to fix
Hole internal diameter is less than optoacoustic ring and sweeps probe outer diameter, can prevent optoacoustic ring from sweeping probe and exit integrated epitheca during withdrawing.
Housing inner diameter is slightly larger than torsion coil outer diameter as a preferred technical solution, and housing hose one end is solid
It is scheduled in the first cylindrical piece, the front end of 3-D scanning part is equipped with the second cylindrical piece, and crossing in the second cylindrical piece has video line three-way hole
Be fixed in the second cylindrical piece with the other end of housing hose fixation hole, the housing hose, second synchronizing wheel it is hollow
Shaft rotates in the second cylindrical piece, and outside is cased with sealing ring, can prevent the water overflowed into from scanning head from entering 3-D scanning
In structure.
The water injection pipe is passed through from snake cyrtosis portion and insertion hose as a preferred technical solution, end and three
The front end connection of sweep test is tieed up, and is located at the second cylindrical piece front end.
The junction portion includes fibre-optical splice and electrical connector as a preferred technical solution, and fibre-optical splice is located at rotation
In rotatable buckle structure, by the fibre-optical splice inside buckle structure protection, it is hardly damaged it；Electrical connector connects for contact pin type
Head is connected with photoacoustic signal line, motor control line, video line respectively, and wherein photoacoustic signal line connects coaxial connector, remaining connects
Metal ferrule is connect, electrical connector shell is Metal shielding shell.
The optical fiber is the optical fiber with glass lock pin as a preferred technical solution,.
The bending snake bone is that four-way is bent snake bone as a preferred technical solution, controls its side by four wirerope
To adjusting, wirerope one end is fixed on bending snake bone front end, and wears from bending snake bone, insertion hose and 3-D scanning partial interior
It crosses, the other end is fixed in control handle.
In order to reach above-mentioned second purpose, the invention adopts the following technical scheme:
The present invention is based on the imaging methods of three-dimensional Photoacoustic endoscope in the bending cavity of snake bone deflecting, include the following steps:
The bending of snake bone upper and lower, left and right four-way is adjusted by operating control handle, and is passed through under the guidance of video image
It is bent cavity, while driving optoacoustic probe in 3-D scanning part is rotated, withdraws scanning, and the three-dimensional optoacoustic of cavity is bent
Image.
Compared with the prior art, the invention has the following advantages and beneficial effects:
The present invention can obtain human body in high definition optical camera and the endoscope of high parsing being integrated in one of photoacoustic imaging
The high clear video image being bent in cavity tissue such as colon road, by based on snake bone head deflecting technology and three-dimensional optoacoustic endoscopy at
As combining, and it is bent the intracorporal Multi-parameter three-dimensional optoacoustic image of chamber under the guidance of video image, increases tradition
The imaging pattern of endoscope optical, and be more easily detected.By photoacoustic signal transmission line and motor control line, video signal cable, LED
Power supply line is connected in the same contact pin type connector, more integrated, and photoacoustic signal line uses coaxial connector, can be effectively
Prevent faint photoacoustic signal by noise jamming, Metal shielding shell further plays the role of electromagnetic shielding.
Detailed description of the invention
Fig. 1 is that the present embodiment is a kind of for realizing in three-dimensional photoacoustic imaging method in the bending cavity based on snake bone deflecting
Sight glass structural schematic diagram.
Fig. 2 is the schematic illustration of the present embodiment.
Fig. 3 is the schematic diagram of internal structure that optical acoustic scanning is popped one's head in the present embodiment.
Fig. 4, Fig. 5, Fig. 6 are integrated epitheca and the structural schematic diagram in first three kinds of directions of cylindrical piece in the present embodiment.
Fig. 7 is the schematic diagram of integral scanning head bending deflecting in the present embodiment.
Fig. 8, Fig. 9 are the structural schematic diagrams of 3-D scanning part and second two kinds of directions of cylindrical piece in the present embodiment.
Figure 10 is the structural schematic diagram of electrical connector in the present embodiment.
Wherein, 1- integral scanning head, 2- snake cyrtosis portion, 3- are inserted into hose, 4- 3-D scanning part, and 5- controls hand
Handle, the junction portion 6-, 7- are bent cavity, 8- rotary scanning, and 9- withdraws scanning, 10- ultrasonic transducer, 11- metallic-membrane plating reflector,
12- lenticule, the micro- bearing of 13-, 14- optical fiber, the first circular through hole of 15-, the second circular through hole of 16-, 17- fan-shaped pylone, in 18-
Hollow round column connector, the first cylindrical piece of 19-, 20- the first cylindrical piece torsion coil housing hose fixation hole, the first cylindrical piece of 21- view
Frequency line three-way hole, 22- fill the water pipe through-hole, 23- rotating electric machine, 24- linear motor, 25- conducting slip ring, the first synchronizing wheel of 26-, 27-
Second synchronizing wheel, 28- synchronous belt, 29- sealing ring, 30- connection structure, the second cylindrical piece of 31-, 32- the second cylindrical piece torsion line
Circle housing hose fixation hole, 33- the second cylindrical piece video line three-way hole, 34- wirerope through-hole, 35- metal ferrule, 36- coaxially connect
Connector, 37- Metal shielding shell.
Specific embodiment
Present invention will now be described in further detail with reference to the embodiments and the accompanying drawings, but embodiments of the present invention are unlimited
In this.
Embodiment
As shown in Figure 1, the present embodiment is a kind of for realizing three-dimensional photoacoustic imaging side in the bending cavity based on snake bone deflecting
The endoscope of method, comprising: integral scanning head 1, snake cyrtosis portion 2, insertion hose 3,3-D scanning part 4, control 5 and of handle
Junction portion 6.
As shown in Fig. 2, three-dimensional photoacoustic imaging method in bending cavity of the present embodiment based on snake bone deflecting, is controlled by operation
Handle processed adjusts the bending of snake bone upper and lower, left and right four-way, so that endoscope head end is done corresponding bending, and image in micro-optical
Pass through bending cavity 7, while rotating electric machine and linear motor in 3-D scanning part under the guidance for the video image that head obtains
Driving optoacoustic probe carries out rotary scanning 8 and withdraws scanning 9, is bent the three-dimensional light sound shadow picture of cavity.With reference to the accompanying drawing
The specific structure of each part is described in detail.
In the present embodiment, the integral scanning head includes that optical acoustic scanning probe, micro-optical camera, integration are outer
Sheath, the optical acoustic scanning probe do rotation in integrated epitheca and withdraw movement, and the micro-optical camera is fixed on one
In outside the pale of civilization sheath.
The outer diameter 5-6mm as shown in figure 3, the optical acoustic scanning is popped one's head in, internal light channel structure are axially distributed from head end
Respectively metallic-membrane plating reflector 11, lenticule 12, optical fiber, the metallic-membrane plating reflector plate high-reflecting film, and reflectivity is greater than 99%, reflecting surface
Inclination angle is 35 degree, and the high-reflecting film is silverskin；The lenslet diameter 1mm to from the laser beam of fiber exit there is collimation to make
With the lenticule is C Lens；The optical fiber is fixed with micro- 13 inner wall of bearing, micro- bearing outer wall and optical acoustic scanning inner probe wall
Fixed, micro- bearing outside diameter 3mm can keep optical fiber not rotate when optical acoustic scanning, which is popped one's head in, to be rotated；The optical fiber 14 is band
The optical fiber of glass core；Ultrasonic transducer 10 is located at the front end of metallic-membrane plating reflector, from the laser beam of fiber exit successively through lenticule
The surface of the ultrasonic transducer is radiated at metallic-membrane plating reflector.
The micro-optical camera head diameter 2-4mm, depth of field 3-100mm, 120 degree of field angle, the micro-optical
Camera is CMOS optical camera, and LED illumination built in the micro-optical camera, illumination intensity can pass through host panel tune
Section.
As shown in Fig. 4, Fig. 5, Fig. 6, the integration epitheca diameter 11-13mm, there is the first circular through hole 15, second in inside
Circular through hole 16 and two fan-shaped pylones 17, the first circular through hole 15 are that optoacoustic ring sweeps probe channel, and the second circular through hole 16 is
Micro-optical camera channel, two fan-shaped pylones are located at the two sides of the first circular through hole 15, for filling the water and being vented, fan
Shape through-hole end is hollow circuit cylinder connector 18, for connecting water injection pipe.Integrated epitheca end be equipped with the first cylindrical piece 19, first
Be respectively arranged in cylindrical piece the first cylindrical piece torsion coil housing hose fixation hole 20, the first cylindrical piece video line three-way hole 21,
Through-hole 22 is filled the water, the first cylindrical piece torsion coil housing hose fixation hole internal diameter is less than optoacoustic ring and sweeps probe outer diameter, can prevent
Only optoacoustic ring sweeps probe and exits integrated epitheca during withdrawing.
The optical acoustic scanning probe outer wall does polishing treatment with the round duct inner wall of the integrated epitheca, to reduce
Frictional resistance when rotation is withdrawn is easy to optoacoustic probe three-dimensional ring and sweeps.The integration epitheca is medical stainless steel material, surface
Chromium plating is easier to enter in bending cavity to increase corrosion-resistant rate and smoothness.
As shown in fig. 7, snake cyrtosis portion connecting integration probe and insertion hose, pass through operating control handle reality
Now integral scanning head upper and lower, left and right four-way is adjusted, snake cyrtosis portion is constituted by being bent snake bone, to outer difference Zi in
To be bent snake bone, mesh grid, rubber tube, bending snake bone one end connects above-mentioned cylindrical piece 1, before hose is inserted into other end connection
End, the bending snake bone are that four-way is bent snake bone, control its direction by four wirerope and adjust, wirerope one end is fixed on curved
Bent snake bone front end, and passed through from bending snake bone, insertion hose and 3-D scanning partial interior, the other end is fixed on control handle
In.
As shown in figure 8, the 3-D scanning part includes rotating electric machine 23, linear motor 24, conducting slip ring 25, synchronizes
Wheel, synchronous belt 28, connection structure 30 and shell, the linear motor control rotating electric machine generate linear motion, rotating electric machine machine
Body is fixed together with conducting slip ring shell (stator terminal) by connection structure, conducting slip ring inner hollow, spin motor shaft with
First synchronizing wheel 26 is connected and fixed, and the second synchronizing wheel 27 is passed through from conducting slip ring hollow hole, is fixed with rotor-end, the first synchronizing wheel
With the second synchronizing wheel by toothed belt transmission, to give the torque transfer of spin motor shaft to conductive sliding ring rotor end, second is same
Step wheel is connect with optical acoustic scanning probe by torsion coil, the torsion coil outer diameter 3mm, by torsion coil by torque transfer
It pops one's head in optical acoustic scanning, so that optical acoustic scanning probe is rotated movement, while moving along a straight line, realize three-dimensional optoacoustic ring
It sweeps.
As shown in figure 9, the torsion coil is passed through from housing hose, housing inner diameter is slightly larger than outside torsion coil
Diameter, housing hose one end are fixed in the first above-mentioned cylindrical piece, and the front end of 3-D scanning part is equipped with the second cylindrical piece
31, interior cross of the second cylindrical piece has outside the second cylindrical piece video line three-way hole 33, wirerope through-hole 34 and the second cylindrical piece torsion coil
Hose fixation hole 32 is covered, the other end of the housing hose is fixed in the second cylindrical piece, the middle idle running of second synchronizing wheel
Axis rotates in the second cylindrical piece, and outside is cased with sealing ring 29, can prevent the water overflowed into from scanning head from entering 3-D scanning
In structure.
The front end of the 3-D scanning part is connected with insertion hose, and rear end is connected with control handle；Above-mentioned water injection pipe
It is passed through from snake cyrtosis portion and insertion hose, end is connect with the front end of 3-D scanning part, and is located at above-mentioned second circle
Column block front end.
In the present embodiment, the junction portion includes fibre-optical splice and electrical connector, and fibre-optical splice is located at rotary buckle
In structure, by the fibre-optical splice inside buckle structure protection, it is hardly damaged it；As shown in Figure 10, electrical connector is contact pin
Formula connector is connected with photoacoustic signal line, motor control line, video line (including built-in LED power line), wherein photoacoustic signal line respectively
Coaxial connector 36 is connected, remaining is all connected with metal ferrule 35, and electrical connector shell is Metal shielding shell 37, and the optical fiber connects
Head connection pulse laser, the electrical connector connect host.
The above embodiment is a preferred embodiment of the present invention, but embodiments of the present invention are not by above-described embodiment
Limitation, other any changes, modifications, substitutions, combinations, simplifications made without departing from the spirit and principles of the present invention,
It should be equivalent substitute mode, be included within the scope of the present invention.
Claims (10)
1. three-dimensional Photoacoustic endoscope in the bending cavity based on snake bone deflecting characterized by comprising integral scanning head, snake
Cyrtosis portion, insertion hose, 3-D scanning part, control handle and junction portion；
The integral scanning head includes optical acoustic scanning probe, micro-optical camera, integrated epitheca, and the optical acoustic scanning is visited
Head does rotation in integrated epitheca and withdraws movement, and the micro-optical camera is fixed in integrated epitheca；
Snake cyrtosis portion connecting integration probe and insertion hose, are realized by operating control handle to integral scanning
Head upper and lower, left and right four-way is adjusted, and snake cyrtosis portion is constituted by being bent snake bone, bending snake bone one end connecting integration scanning
The rear end of probe, the front end of other end connection insertion hose；
The front end of the 3-D scanning part is connected with insertion hose, and rear end is connected with control handle, the 3-D scanning part
Including rotating electric machine, linear motor, conducting slip ring, the first synchronizing wheel, the second synchronizing wheel, synchronous belt, connection structure and shell, institute
It states linear motor control rotating electric machine and generates linear motion, rotating electric machine fuselage is fixed with conducting slip ring shell by connection structure
Together, conducting slip ring inner hollow, spin motor shaft are connected and fixed with the first synchronizing wheel, and the second synchronizing wheel is from conducting slip ring
Emptying aperture passes through, and fixes with rotor-end, and the first synchronizing wheel and the second synchronizing wheel are by toothed belt transmission, thus by spin motor shaft
Torque transfer gives conductive sliding ring rotor end, and the second synchronizing wheel is popped one's head in optical acoustic scanning and connect by torsion coil, passes through torsion line
Circle transmits torque to optical acoustic scanning probe, so that optical acoustic scanning probe is rotated movement, while moving along a straight line, realizes
Three-dimensional optoacoustic ring is swept.
2. three-dimensional Photoacoustic endoscope in the bending cavity according to claim 1 based on snake bone deflecting, which is characterized in that described
Optical acoustic scanning is popped one's head in outer diameter 5-6mm, the axially distributed respectively metallic-membrane plating reflector, micro- from head end of internal light channel structure
Mirror/lenticule group and optical fiber, the metallic-membrane plating reflector plate high-reflecting film, and reflectivity is greater than 99%, and reflection surface inclination is 35 degree；It is described
Lenticule/lenticule group diameter 1-3mm has collimation or focussing force to from the laser beam of fiber exit；The optical fiber with it is micro-
Bearing inner wall is fixed, and micro- bearing outer wall is fixed with optical acoustic scanning inner probe wall, can keep light when optical acoustic scanning, which is popped one's head in, to be rotated
Fibre does not rotate；The front end of the metallic-membrane plating reflector is additionally provided with ultrasonic transducer, from the laser beam of fiber exit successively through lenticule/
Lenticule group and metallic-membrane plating reflector are radiated at the surface of the ultrasonic transducer.
3. three-dimensional Photoacoustic endoscope in the bending cavity according to claim 1 based on snake bone deflecting, which is characterized in that described
Micro-optical camera head diameter 2-4mm, depth of field 3-100mm, 120 degree of field angle, built-in LED illumination, illumination intensity can lead to
Cross host panel adjusting.
4. three-dimensional Photoacoustic endoscope in the bending cavity according to claim 1 based on snake bone deflecting, which is characterized in that described
There are the first circular through hole, the second circular through hole and two fan-shaped pylones in integrated epitheca diameter 11-13mm, inside, and first is round
Through-hole is that optoacoustic ring sweeps probe channel, the second circular through hole micro-optical camera channel, and two fan-shaped pylones are located at the
The two sides of one circular through hole, for filling the water and being vented, fan-shaped pylone end is hollow circuit cylinder connector, for connecting water injection pipe；Institute
Integrated epitheca end is stated equipped with the first cylindrical piece, be respectively arranged in the first cylindrical piece torsion coil housing hose fixation hole,
Pipe through-hole and video line three-way hole are filled the water, the torsion coil housing hose fixation hole internal diameter is less than optoacoustic ring and sweeps probe outer diameter, can
It prevents optoacoustic ring from sweeping probe and exits integrated epitheca during withdrawing.
5. three-dimensional Photoacoustic endoscope in the bending cavity according to claim 4 based on snake bone deflecting, which is characterized in that housing
Inner diameter is slightly larger than torsion coil outer diameter, and housing hose one end is fixed in the first cylindrical piece, 3-D scanning part
Front end is equipped with the second cylindrical piece, and crossing in the second cylindrical piece has video line three-way hole and housing hose fixation hole, the housing hose
The other end is fixed in the second cylindrical piece, and the hollow axle of second synchronizing wheel rotates in the second cylindrical piece, outer sheath
There is sealing ring, can prevent from entering in 3-D scanning structure from the water that scanning head overflows into.
6. three-dimensional Photoacoustic endoscope in the bending cavity according to claim 5 based on snake bone deflecting, which is characterized in that described
Water injection pipe is passed through from snake cyrtosis portion and insertion hose, and end is connect with the front end of 3-D scanning part, and is located at second
Cylindrical piece front end.
7. three-dimensional Photoacoustic endoscope in the bending cavity according to claim 1 based on snake bone deflecting, which is characterized in that described
Junction portion includes fibre-optical splice and electrical connector, and fibre-optical splice is located in rotary buckle structure, is protected by buckle structure
Internal fibre-optical splice, is hardly damaged it；Electrical connector is contact pin type connector, is connected with photoacoustic signal line, motor control respectively
Line, video line, wherein photoacoustic signal line connects coaxial connector, remaining is all connected with metal ferrule, and electrical connector shell is metal
Shield shell.
8. three-dimensional Photoacoustic endoscope in the bending cavity according to claim 1 based on snake bone deflecting, which is characterized in that described
Optical fiber is the optical fiber with glass lock pin.
9. three-dimensional Photoacoustic endoscope in the bending cavity according to claim 1 based on snake bone deflecting, which is characterized in that described
Being bent snake bone is that four-way is bent snake bone, controls its direction by four wirerope and adjusts, and wirerope one end is fixed on bending snake bone
Front end, and passed through from bending snake bone, insertion hose and 3-D scanning partial interior, the other end is fixed in control handle.
10. using in the bending cavity described in any one of claim 1-9 based on snake bone deflecting three-dimensional Photoacoustic endoscope at
Image space method, which is characterized in that include the following steps:
The bending of snake bone upper and lower, left and right four-way is adjusted by operating control handle, and passes through bending under the guidance of video image
Cavity, while driving optoacoustic probe in 3-D scanning part is rotated, withdraws scanning, and the three-dimensional light sound shadow of cavity is bent
Picture.
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Cited By (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109528147A (en) * | 2019-01-14 | 2019-03-29 | 聚品(上海)生物科技有限公司 | Rod-shaped photoelectricity plug and photoelectricity connection seat for superfine electric endoscopic system |
| CN109998455A (en) * | 2019-05-06 | 2019-07-12 | 河南科技大学第一附属医院 | A kind of endoscope |
| CN110811707A (en) * | 2019-11-15 | 2020-02-21 | 温州市中医院 | Improved water needle knife and implementation steps for treating knee joint diseases |
| CN111588334A (en) * | 2020-06-22 | 2020-08-28 | 妙思医疗科技(上海)有限公司 | Operating handle for endoscope |
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Citations (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20110275890A1 (en) * | 2009-01-09 | 2011-11-10 | Washington University In St. Louis | Miniaturized photoacoustic imaging apparatus including a rotatable reflector |
| CN102499719A (en) * | 2011-09-30 | 2012-06-20 | 汕头市超声仪器研究所有限公司 | Ultrasonic probe for endoscope |
| CN103690141A (en) * | 2013-12-26 | 2014-04-02 | 广州佰奥廷电子科技有限公司 | Internal rectal optical, optoacoustic and ultrasonic multimode imaging endoscope and imaging method thereof |
| CN105769128A (en) * | 2016-05-06 | 2016-07-20 | 华南师范大学 | Integrated opto-acoustic, ultrasonic and opto-acoustic elastic endoscopic imaging device and method thereof |
| CN106821282A (en) * | 2017-01-18 | 2017-06-13 | 张波 | A kind of disposable electric medical endoscope device |
| CN107106135A (en) * | 2015-06-18 | 2017-08-29 | 奥林巴斯株式会社 | Endoscope |
| CN107638168A (en) * | 2017-09-19 | 2018-01-30 | 华南师范大学 | A kind of Photoacoustic endoscope and implementation method adaptively focused based on printing opacity entrant sound water pocket |
| US20180055343A1 (en) * | 2016-08-24 | 2018-03-01 | Unist(Ulsan National Institute Of Science And Tech Nology) | Photoacoustic and ultrasonic endoscopy system including a coaxially configured optical and electromagnetic rotary waveguide assembly and implementation method thereof |
-
2018
- 2018-06-29 CN CN201810695072.0A patent/CN109044248B/en active Active
Patent Citations (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20110275890A1 (en) * | 2009-01-09 | 2011-11-10 | Washington University In St. Louis | Miniaturized photoacoustic imaging apparatus including a rotatable reflector |
| CN102499719A (en) * | 2011-09-30 | 2012-06-20 | 汕头市超声仪器研究所有限公司 | Ultrasonic probe for endoscope |
| CN103690141A (en) * | 2013-12-26 | 2014-04-02 | 广州佰奥廷电子科技有限公司 | Internal rectal optical, optoacoustic and ultrasonic multimode imaging endoscope and imaging method thereof |
| CN107106135A (en) * | 2015-06-18 | 2017-08-29 | 奥林巴斯株式会社 | Endoscope |
| CN105769128A (en) * | 2016-05-06 | 2016-07-20 | 华南师范大学 | Integrated opto-acoustic, ultrasonic and opto-acoustic elastic endoscopic imaging device and method thereof |
| US20180055343A1 (en) * | 2016-08-24 | 2018-03-01 | Unist(Ulsan National Institute Of Science And Tech Nology) | Photoacoustic and ultrasonic endoscopy system including a coaxially configured optical and electromagnetic rotary waveguide assembly and implementation method thereof |
| CN106821282A (en) * | 2017-01-18 | 2017-06-13 | 张波 | A kind of disposable electric medical endoscope device |
| CN107638168A (en) * | 2017-09-19 | 2018-01-30 | 华南师范大学 | A kind of Photoacoustic endoscope and implementation method adaptively focused based on printing opacity entrant sound water pocket |
Cited By (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109528147A (en) * | 2019-01-14 | 2019-03-29 | 聚品(上海)生物科技有限公司 | Rod-shaped photoelectricity plug and photoelectricity connection seat for superfine electric endoscopic system |
| CN109528147B (en) * | 2019-01-14 | 2023-11-21 | 爱尔博微视(上海)医疗科技有限公司 | Rod-shaped photoelectric plug and photoelectric connecting seat for superfine electronic endoscope system |
| CN109998455A (en) * | 2019-05-06 | 2019-07-12 | 河南科技大学第一附属医院 | A kind of endoscope |
| CN110811707A (en) * | 2019-11-15 | 2020-02-21 | 温州市中医院 | Improved water needle knife and implementation steps for treating knee joint diseases |
| CN110811707B (en) * | 2019-11-15 | 2021-05-11 | 温州市中医院 | Improved generation water needle sword |
| CN111588334A (en) * | 2020-06-22 | 2020-08-28 | 妙思医疗科技(上海)有限公司 | Operating handle for endoscope |
| CN112315502A (en) * | 2020-11-26 | 2021-02-05 | 深圳开立生物医疗科技股份有限公司 | Drive control device of intravascular ultrasonic probe and intravascular ultrasonic imaging system |
| CN113996961B (en) * | 2021-11-18 | 2023-01-13 | 潍坊新松机器人自动化有限公司 | Welding robot in limited operation space |
| CN113996961A (en) * | 2021-11-18 | 2022-02-01 | 潍坊新松机器人自动化有限公司 | Welding robot in limited operation space |
| CN113925443A (en) * | 2021-12-15 | 2022-01-14 | 深圳市海瑞洋科技有限公司 | 3D holographic artificial intelligence minimally invasive endoscope system |
| CN114847866A (en) * | 2022-03-30 | 2022-08-05 | 图湃(北京)医疗科技有限公司 | Side OCT imaging miniature optical fiber endoscope probe and manufacturing method thereof |
| CN117796852A (en) * | 2024-02-28 | 2024-04-02 | 中国科学院深圳先进技术研究院 | Rotation retracting system for three-dimensional imaging and data analysis method thereof |
| CN117796852B (en) * | 2024-02-28 | 2024-08-16 | 中国科学院深圳先进技术研究院 | Rotation retracting system for three-dimensional imaging and data analysis method thereof |
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