CN108970521A - Excipient substance is gelatinized equipment and excipient substance gelatinizing method - Google Patents
Excipient substance is gelatinized equipment and excipient substance gelatinizing method Download PDFInfo
- Publication number
- CN108970521A CN108970521A CN201811117830.7A CN201811117830A CN108970521A CN 108970521 A CN108970521 A CN 108970521A CN 201811117830 A CN201811117830 A CN 201811117830A CN 108970521 A CN108970521 A CN 108970521A
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- Prior art keywords
- gelatinization
- gelatinization pot
- pot
- thickener
- gelatinized
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- 239000000546 pharmaceutical excipient Substances 0.000 title claims abstract description 33
- 239000000126 substance Substances 0.000 title claims abstract description 33
- 238000000034 method Methods 0.000 title claims abstract description 26
- 239000000463 material Substances 0.000 claims abstract description 77
- 239000002562 thickening agent Substances 0.000 claims abstract description 45
- 238000003756 stirring Methods 0.000 claims abstract description 34
- 239000007788 liquid Substances 0.000 claims abstract description 30
- 239000002994 raw material Substances 0.000 claims abstract description 28
- 238000003860 storage Methods 0.000 claims abstract description 25
- 230000007246 mechanism Effects 0.000 claims abstract description 20
- 238000010438 heat treatment Methods 0.000 claims abstract description 10
- 239000002253 acid Substances 0.000 claims description 36
- 238000007790 scraping Methods 0.000 claims description 17
- 239000012530 fluid Substances 0.000 claims description 11
- 230000000694 effects Effects 0.000 claims description 9
- 238000007599 discharging Methods 0.000 claims description 8
- 230000009514 concussion Effects 0.000 claims description 5
- 238000009826 distribution Methods 0.000 claims description 3
- 238000009434 installation Methods 0.000 claims description 3
- 238000004382 potting Methods 0.000 claims 1
- 238000005516 engineering process Methods 0.000 abstract description 5
- 238000004519 manufacturing process Methods 0.000 abstract description 2
- 239000002002 slurry Substances 0.000 abstract 1
- 239000000243 solution Substances 0.000 description 33
- 230000008569 process Effects 0.000 description 14
- 108010066057 cabin-1 Proteins 0.000 description 7
- 230000008859 change Effects 0.000 description 4
- 238000010586 diagram Methods 0.000 description 4
- 238000013019 agitation Methods 0.000 description 3
- 239000000203 mixture Substances 0.000 description 3
- 230000004308 accommodation Effects 0.000 description 2
- 230000005484 gravity Effects 0.000 description 2
- 239000000843 powder Substances 0.000 description 2
- 206010068150 Acoustic shock Diseases 0.000 description 1
- 238000009825 accumulation Methods 0.000 description 1
- 150000007513 acids Chemical class 0.000 description 1
- 230000009471 action Effects 0.000 description 1
- 230000008901 benefit Effects 0.000 description 1
- 230000001351 cycling effect Effects 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- -1 easier to operate Substances 0.000 description 1
- 230000002708 enhancing effect Effects 0.000 description 1
- 239000004744 fabric Substances 0.000 description 1
- 238000002347 injection Methods 0.000 description 1
- 239000007924 injection Substances 0.000 description 1
- 230000003252 repetitive effect Effects 0.000 description 1
- 238000005096 rolling process Methods 0.000 description 1
- 238000003466 welding Methods 0.000 description 1
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F33/00—Other mixers; Mixing plants; Combinations of mixers
- B01F33/80—Mixing plants; Combinations of mixers
- B01F33/82—Combinations of dissimilar mixers
- B01F33/822—Combinations of dissimilar mixers with moving and non-moving stirring devices in the same receptacle
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F27/00—Mixers with rotary stirring devices in fixed receptacles; Kneaders
- B01F27/80—Mixers with rotary stirring devices in fixed receptacles; Kneaders with stirrers rotating about a substantially vertical axis
- B01F27/90—Mixers with rotary stirring devices in fixed receptacles; Kneaders with stirrers rotating about a substantially vertical axis with paddles or arms
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F31/00—Mixers with shaking, oscillating, or vibrating mechanisms
- B01F31/80—Mixing by means of high-frequency vibrations above one kHz, e.g. ultrasonic vibrations
- B01F31/83—Mixing by means of high-frequency vibrations above one kHz, e.g. ultrasonic vibrations comprising a supplementary stirring element
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F31/00—Mixers with shaking, oscillating, or vibrating mechanisms
- B01F31/80—Mixing by means of high-frequency vibrations above one kHz, e.g. ultrasonic vibrations
- B01F31/85—Mixing by means of high-frequency vibrations above one kHz, e.g. ultrasonic vibrations with a vibrating element inside the receptacle
Landscapes
- Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Accessories For Mixers (AREA)
Abstract
The present invention relates to medical production equipment technologies, are gelatinized equipment and excipient substance gelatinizing method more particularly, to a kind of excipient substance.It includes raw material cabin, feed pipe, gelatinization pot and thickener storehouse that excipient substance, which is gelatinized equipment,；Feeding mechanism will be in the feedstock transportation to gelatinization pot in raw material cabin.Agitating paddle, folding flitch and Vibration Box are provided in gelatinization pot；Agitating paddle is placed in the intracorporal thickener of tank for stirring；One end of folding flitch is connected with the interior sidewall surface of tank body, for keeping the thickener close to gelatinization pot inner wall mobile towards agitating paddle；Vibration Box is located at gelatinization pot bottom, uniform for shaking the thickener of bottom in gelatinization pot；Gelatinization pot is double-layer structure, forms storage space between the double-layer structure of gelatinization pot, for storing heating liquid.The gelatinization pot of the application passes through the cooperation of folding flitch, stirring slurry and Vibration Box, so that material comes into full contact with agitating paddle, so that material is gelatinized more evenly；And by heating of the gelatinization pot to material, the gelatinization speed of material can be accelerated.
Description
Technical field
The present invention relates to medical production equipment technologies, are gelatinized equipment more particularly, to a kind of excipient substance and drug is auxiliary
Expect gelatinizing method.
Background technique
It is mostly used gelatinization pot in material gelatinization process, and stirring rod is installed in gelatinization pot, for stirring inside gelatinization pot
Material so that material and acids are sufficiently mixed gelatinization；However material can be constantly to the inner wall of gelatinization pot in whipping process
It moves and accumulates, so that material stirring is uneven, gelatinization process is uneven, in addition, only relying on room temperature, hence it is evident that be not achieved expected
Pasting effect reduces gelatinization efficiency, extends gelatinization time.
Summary of the invention
The application's is designed to provide a kind of excipient substance gelatinization equipment and excipient substance gelatinizing method, existing to solve
Thickener stirring is uneven in gelatinization pot present in technology, and cannot achieve and heat to thickener, leads to the technology of pasting effect difference
Problem.
This application provides a kind of excipient substances to be gelatinized equipment, comprising: raw material cabin, feeding mechanism, gelatinization pot and thickener storehouse；
One end of the feeding mechanism is connected with the raw material cabin, the other end of the feeding mechanism and the gelatinization pot
Feed inlet is connected；The gelatinization pot discharge port is connected with the thickener storehouse；
Agitating paddle, folding flitch and Vibration Box are provided in the gelatinization pot；The agitating paddle is placed in the gelatinization for stirring
Thickener in tank；One end of the folding flitch is connected with the interior sidewall surface of the gelatinization pot, for making close to the gelatinization pot
The thickener of inner wall is mobile towards the agitating paddle；The Vibration Box is located at the gelatinization pot bottom, for making in the gelatinization pot
The thickener concussion of bottom is uniform；
The gelatinization pot is double-layer structure, forms storage space between the double-layer structure of the gelatinization pot, is added for storing
Hot liquid.
Further, the gelatinization pot upper end is additionally provided with acid solution filling opening, the acid solution filling opening by fluid filling pump with
Acid solution tank is connected, for acid solution to be added into the gelatinization pot.
Further, the folding flitch includes connecting rod and scraping wings；One end of the connecting rod and the gelatinization pot
Interior sidewall surface be connected, the other end of the connecting rod is connected with the scraping wings；The scraping wings and the gelatinization pot
Axis in angle be arranged.
Further, the agitating paddle includes stirring rod and paddle；The first driving dress is provided with outside the gelatinization pot
It sets, the first driving device is connected with the stirring rod, for driving the stirring rod to rotate；The paddle setting exists
On the stirring rod；The quantity of the paddle be it is multiple, multiple paddles are along circumferentially staggered point of the stirring rod
Cloth.
Further, the Vibration Box is connected with supersonic generator；The quantity of the Vibration Box is multiple, multiple vibrations
Box is uniformly distributed in bottom in the gelatinization pot.
Further, humidity discharging mouth, oil inlet and oil outlet are provided on the gelatinization pot；Wherein, humidity discharging mouth position
Moisture in the top of the tank, for being discharged in the gelatinization pot；The oil inlet is located at gelatinization pot outside wall surface lower part,
The oil outlet is located at gelatinization pot outside wall surface top, the oil inlet and the oil outlet respectively with the storage space phase
Connection；The oil inlet is for conveying in liquid to the storage space, and the oil outlet is for being discharged in the storage space
Liquid.
Further, the feeding mechanism includes feed pipe, the second driving device, spiral flood dragon and support frame；
One end of the feed pipe is provided with first charging aperture, and the other end of the feed pipe is provided with the first discharge port；
The spiral flood dragon is located in the feed pipe, and the spiral flood dragon is arranged along the extending direction of the feed pipe；Described
For two driving devices for driving the spiral flood dragon to rotate, the spiral flood dragon rotation is able to drive material from first charging
Mouth enters the feed pipe and is discharged from first discharge port；The feed pipe is set on support frame as described above.
Further, observation window and end cap are additionally provided on the gelatinization pot；Wherein, the observation window is located at the paste
Change tank top, is gelatinized situation for observing the thickener inside the gelatinization pot；The end cap can be located on the observation window,
For covering the observation window.
Further, mounting plate and temperature measuring gauge are additionally provided on the outer wall of the gelatinization pot；The mounting plate and the paste
The outside wall surface for changing tank is connected；Mounting groove is offered on the mounting plate, the temperature measuring gauge is embedded in the mounting groove.
Present invention also provides a kind of excipient substance gelatinizing methods, comprising the following steps:
Raw material is entered by feeding mechanism and is delivered in gelatinization pot in step 100, raw material cabin；
Heating liquid is added into the storage space of the gelatinization pot for step 200；
Step 300 opens fluid filling pump, and acid solution is added into the gelatinization pot by acid solution filling opening；
Step 400 closes fluid filling pump, starting agitating paddle, is uniformly mixed material and acid solution in the gelatinization pot, and
It heats and obtains thickener under the heat effect of liquid；
Step 500, thickener obtained enter thickener storehouse；Agitating paddle is closed, being passed through for heating liquid is stopped, completing material paste
Change process.
Compared with prior art, the invention has the benefit that
Excipient substance gelatinization equipment provided by the present application includes raw material cabin, feed pipe, gelatinization pot and thickener storehouse；Raw material cabin is used
In storage raw material, feeding mechanism is used to realize the process of automatic charging in the feedstock transportation to gelatinization pot in raw material cabin.Raw material
Into after gelatinization pot, be added acid solution thereto, gelatinization pot can in it raw material and acid solution uniformly mix and be gelatinized, thus
To thickener, thickener is able to enter in thickener storehouse and keeps in.
In gelatinization process, the agitating paddle in gelatinization pot can stir the material in tank；And due to object in agitation
Material can be mobile to the inner wall of gelatinization pot, rolls over flitch at this time and then stops the movement of material, so that will be close to gelatinization pot inner wall
The direction of material to close agitating paddle is mobile, and then increases the contact probability of agitating paddle and material, so that agitating paddle and object
Material comes into full contact with, so that material is stirred more evenly, so that material is gelatinized more evenly, improves gelatinization efficiency, and keep away
Exempt to be mingled with dry powder in thickener；In addition, material can lodge in bottom in gelatinization pot under the effect of gravity, it is difficult for agitating paddle to bottom
Material carry out uniform stirring, therefore Vibration Box is arranged in the gelatinization equipment of the embodiment of the present application bottom in tank body, and Vibration Box can send out
Raw concussion is gelatinized the material in tank uniform so that bottoms material in tank be avoided to accumulate.
Also, the gelatinization pot of the embodiment of the present application be double-layer structure, inside can be used for storing liquid, particularly with storage
The liquid of heat, can heat the intracorporal material of tank, improve gelatinization efficiency, reduce gelatinization time.
Detailed description of the invention
It, below will be to specific in order to illustrate more clearly of the specific embodiment of the invention or technical solution in the prior art
Embodiment or attached drawing needed to be used in the description of the prior art be briefly described, it should be apparent that, it is described below
Attached drawing is some embodiments of the present invention, for those of ordinary skill in the art, before not making the creative labor
It puts, is also possible to obtain other drawings based on these drawings.
Fig. 1 is the structural schematic diagram that excipient substance provided in an embodiment of the present invention is gelatinized equipment；
Fig. 2 is the overall structure diagram of gelatinization pot provided in an embodiment of the present invention；
Fig. 3 is the schematic diagram of internal structure of gelatinization pot provided in an embodiment of the present invention；
Fig. 4 is the structural schematic diagram of feeding mechanism provided in an embodiment of the present invention.
Appended drawing reference:
1- raw material cabin, 2- feeding mechanism, 201- feed pipe, the second driving device of 202-, 203- spiral flood dragon, 204- first
Feed inlet, the first discharge port of 205-, 3- gelatinization pot, 301- stirring rod, 302- paddle, 303- connecting rod, 304- scraping wings,
305- Vibration Box, 306- acid solution filling opening, 307- humidity discharging mouth, 308- oil inlet, 309- oil outlet, the storage space 310-, 311-
One driving device, 312- observation window, 313- end cap, 314- mounting plate, 315- temperature measuring gauge, 316- gelatinization pot feed inlet, 317- paste
Change tank discharge port, 4- thickener storehouse.
Specific embodiment
Technical solution of the present invention is clearly and completely described below in conjunction with attached drawing, it is clear that described implementation
Example is a part of the embodiment of the present invention, instead of all the embodiments.
The component for the embodiment of the present invention for usually describing and showing in attached drawing here can be with a variety of different configurations
To arrange and design.Therefore, the detailed description of the embodiment of the present invention provided in the accompanying drawings is not intended to limit below and is wanted
The scope of the present invention of protection is sought, but is merely representative of selected embodiment of the invention.
Based on the embodiments of the present invention, those of ordinary skill in the art are obtained without making creative work
The every other embodiment obtained, shall fall within the protection scope of the present invention.
In the description of the present invention, it should be noted that term " center ", "upper", "lower", "left", "right", "vertical",
The orientation or positional relationship of the instructions such as "horizontal", "inner", "outside" be based on the orientation or positional relationship shown in the drawings, merely to
Convenient for description the present invention and simplify description, rather than the device or element of indication or suggestion meaning must have a particular orientation,
It is constructed and operated in a specific orientation, therefore is not considered as limiting the invention.In addition, term " first ", " second ",
" third " is used for descriptive purposes only and cannot be understood as indicating or suggesting relative importance.
In the description of the present invention, it should be noted that unless otherwise clearly defined and limited, term " installation ", " phase
Even ", " connection " shall be understood in a broad sense, for example, it may be being fixedly connected, may be a detachable connection, or be integrally connected；It can
To be mechanical connection, it is also possible to be electrically connected；It can be directly connected, can also can be indirectly connected through an intermediary
Connection inside two elements.For the ordinary skill in the art, above-mentioned term can be understood at this with concrete condition
Concrete meaning in invention.
Equipment and excipient substance are gelatinized referring to the excipient substance of Fig. 1 to Fig. 4 description according to some embodiments of the invention
Gelatinizing method.
Referring to FIG. 1 to FIG. 4, this application provides a kind of excipient substances to be gelatinized equipment, comprising: raw material cabin 1, feeder
Structure 2, gelatinization pot 3 and thickener storehouse 4；One end of feeding mechanism 2 is connected with raw material cabin 1, the other end and gelatinization pot of feeding mechanism 2
Feed inlet 316 is connected；Gelatinization pot discharge port 317 is connected with thickener storehouse 4；Be provided in gelatinization pot 3 agitating paddle, folding flitch and
Vibration Box 305；Agitating paddle is placed in the intracorporal thickener of tank for stirring；One end of folding flitch is connected with the interior sidewall surface of tank body, uses
In keeping the thickener close to 3 inner wall of gelatinization pot mobile towards agitating paddle；Vibration Box 305 is located at 3 bottom of gelatinization pot, for making gelatinization pot
The thickener concussion of bottom is uniform in 3；Gelatinization pot 3 is double-layer structure, forms storage space 310 between the double-layer structure of gelatinization pot 3,
Liquid is heated for storing.
It is shown in Figure 1, excipient substance provided by the embodiments of the present application gelatinization equipment include raw material cabin 1, feed pipe 201,
Gelatinization pot 3 and thickener storehouse 4；Raw material cabin 1 is used for for storing raw material, feeding mechanism 2 by the feedstock transportation in raw material cabin 1 to gelatinization
In tank 3, the process of automatic charging is realized.After raw material enters gelatinization pot 3, acid solution is added thereto, gelatinization pot 3 can be in it
Raw material and acid solution are uniformly mixed and are gelatinized, to obtain thickener, thickener is able to enter in thickener storehouse 4 and keeps in.
Shown in Figure 3, in gelatinization process, the agitating paddle in gelatinization pot 3 can stir the material in tank；And due to
Material can be mobile to the inner wall of gelatinization pot 3 in agitation, rolls over flitch at this time and then stops the movement of material, so that will be close to paste
The direction for changing material to the close agitating paddle of 3 inner wall of tank is mobile, and then increases the contact probability of agitating paddle and material, and then make
It obtains agitating paddle to come into full contact with material, so that material is stirred more evenly, so that material is gelatinized more evenly, improves paste
Change efficiency, and avoids being mingled with dry powder in thickener；In addition, material can lodge in bottom in gelatinization pot 3 under the effect of gravity, for stirring
Paddle is difficult to carry out the material of bottom uniform stirring, therefore Vibration Box is arranged in the gelatinization equipment of the embodiment of the present application bottom in tank body
305, Vibration Box 305 can shake, so that bottoms material in tank be avoided to accumulate, be gelatinized the material in tank uniform.
Also, shown in Figure 3, the gelatinization pot 3 of the embodiment of the present application is double-layer structure, inside can be used for storing liquid
Body can heat the intracorporal material of tank particularly with the liquid of storage heat, improve gelatinization efficiency, reduce gelatinization time.
When the excipient substance of specifically used the application is gelatinized equipment, material is delivered to by gelatinization pot 3 by feed pipe 201
Interior, material sprinkling or injection acid solution into gelatinization pot 3, the rotation of driving agitating paddle and Vibration Box 305 shake, and keep material and acid solution mixed
It closes uniformly, meanwhile, then the liquid such as hot oil are passed into the storage space 310 formed between the double-layer structure of tank body, in tank body
Material heated, and then realize the gelatinization to material, in the process, folding flitch constantly will be close in gelatinization pot 3
The material of wall surface is constantly to push at agitating paddle, so that all materials are uniformly stirred, improves gelatinization efficiency.When
So, hot oil can also be first passed into storage space 310, preheat tank body, then material is added into tank body, operation order can be according to reality
Border needs to be configured.
As it can be seen that the folding flitch in gelatinization pot 3 provided by the invention can make the thickener in close inner tank wall face to agitating paddle
It is mobile, so that material comes into full contact with agitating paddle, so that material is gelatinized more evenly；And it is formed and is held between the double-layer structure of tank body
Receive space, accommodation space can store hot oil, and then heat to the intracorporal material of tank, accelerate the gelatinization speed of material.
Wherein, optionally, gelatinization pot 3 include be sequentially connected the coniform head shell connect, cylindric central enclosure with
And the tail portion shell of inverted conical shape, and the center line of three coincides；Agitating paddle is located at the centerline of cylindrical shell, folding
The material that flitch can be pushed closer to inner tank wall face is mobile to the agitating paddle of the centerline of tank body.Certainly, the shape of gelatinization pot 3
Shape is not limited only to this.
Wherein, optionally, the quantity for rolling over flitch is not limited only to one, can also be configured according to actual needs to be multiple.
It is shown in Figure 2, in one embodiment of the application, it is preferable that 3 upper end of gelatinization pot is additionally provided with acid solution liquid feeding
Mouth 306, acid solution filling opening 306 is connected by fluid filling pump with acid solution tank, for acid solution to be added into gelatinization pot 3.
In this embodiment, 3 upper end of gelatinization pot also sets up acid solution filling opening 306, for acid solution to be added into gelatinization pot 3；
And the controllability being added for enhancing acid solution, acid solution filling opening 306 are connected by fluid filling pump with acid solution tank, and fluid filling pump control is passed through
The addition of relieving haperacidity liquid, easier to operate, liquid feeding process and liquid volume added are more controllable.
It is shown in Figure 3, in one embodiment of the application, it is preferable that folding flitch includes connecting rod 303 and pusher
Plate 304；One end of connecting rod 303 is connected with the interior sidewall surface of gelatinization pot 3, the other end and 304 phase of scraping wings of connecting rod 303
Connection；The axis of scraping wings 304 and gelatinization pot 3 is arranged in angle.
In this embodiment, folding flitch includes connecting rod 303 and scraping wings 304, wherein scraping wings 304 passes through connection
Bar 303 is connected with the inner wall of gelatinization pot 3, and it is mobile to the inner wall of tank body in agitation that scraping wings 304 can keep out material
Path, to force material mobile towards agitating paddle.And the axis of scraping wings 304 and gelatinization pot 3 is arranged in angle, scraping wings
Close to 3 inner wall of gelatinization pot, the lower end of scraping wings 304 is relatively distant from 3 inner wall of gelatinization pot for 304 upper end, i.e. scraping wings 304 is to updip
Tiltedly, so that scraping wings 304 can not only push material to movement at agitating paddle, and material can be pushed up, avoids object
Material accumulation downwards, so that material be enable preferably uniformly to be gelatinized.
It is shown in Figure 3, in one embodiment of the application, it is preferable that agitating paddle includes stirring rod 301 and stirring
Leaf 302；It is provided with first driving device 311 outside gelatinization pot 3, first driving device 311 is connected with stirring rod 301, for driving
Dynamic stirring rod 301 rotates；Paddle 302 is arranged on stirring rod 301；The quantity of paddle 302 is multiple, multiple paddles
302 along stirring rod 301 circumferentially staggered distribution.
In this embodiment, it is provided with first driving device 311 outside gelatinization pot 3, is stirred by the driving of first driving device 311
Mix the start and stop of paddle；Agitating paddle includes stirring rod 301 and paddle 302, and multiple paddles 302 are provided on stirring rod 301, more
A paddle 302 along stirring rod 301 circumferentially staggered distribution, to comprehensively be stirred to the material in gelatinization pot 3.
It is shown in Figure 3, in one embodiment of the application, it is preferable that Vibration Box 305 is connected with supersonic generator
It connects；The quantity of Vibration Box 305 be it is multiple, multiple Vibration Boxes 305 are uniformly distributed in bottom in gelatinization pot 3.
In this embodiment, Vibration Box 305 is connected by cable with supersonic generator, to realize the super of Vibration Box 305
The acoustic shock effect of swinging, concussion effect is more preferable, reacts material preferably with acid solution.And supersonic generator is located at outside gelatinization pot 3, vibration
Box 305 is located in gelatinization pot 3, can open up on gelatinization pot 3 and hole occurs Vibration Box 305 is made to be connected with supersonic generator.This
Outside, the quantity of Vibration Box 305 is multiple, and multiple Vibration Boxes 305 are uniformly distributed in bottom in gelatinization pot 3, so as to in gelatinization pot 3
The material of bottom is comprehensively shaken, and prevents the material of 3 edge of gelatinization pot from can not mix with acid solution.
It should be noted that supersonic generator used in the embodiment of the present application and Vibration Box 305 are in the prior art
Common ultrasonic equipment.
Shown in referring to figs. 2 and 3, in one embodiment of the application, it is preferable that be provided with humidity discharging mouth on gelatinization pot 3
307, oil inlet 308 and oil outlet 309；Wherein, humidity discharging mouth 307 is located at top of the tank, the tide for being discharged in gelatinization pot 3
Gas；Oil inlet 308 is located at 3 outside wall surface lower part of gelatinization pot, and oil outlet 309 is located at 3 outside wall surface top of gelatinization pot, 308 He of oil inlet
Oil outlet 309 is connected with storage space 310 respectively；Oil inlet 308 is for conveying in liquid to storage space 310, oil outlet
309 liquid for being discharged in storage space 310.
In this embodiment, humidity discharging mouth 307, oil inlet 308 and oil outlet 309 are provided on gelatinization pot 3, wherein row
Tide port 307 is for being discharged the steam that material generates in gelatinization process；And hot oil or other liquid can enter from oil inlet 308
Into the storage space of gelatinization pot 3 310, hot oil is sealed in storage space 310, and using heat transfer principle, hot oil passes through tank
Body passes to the material in gelatinization pot 3, and then carries out Heat Gelatinization to material；It, can be from oil outlet when the temperature of hot oil reduces
309 release hot oil, then are passed through new hot oil into accommodation space again from feed inlet, to keep temperature required for material gelatinization
Degree.
Wherein, optionally, the hot oil released from oil outlet 309 can also come back to boiler room by exterior line and be added
Heat, repetitive cycling use, and save the energy.
It is shown in Figure 4, in one embodiment of the application, it is preferable that feeding mechanism 2 includes feed pipe 201, second
Driving device 202, spiral flood dragon 203 and support frame；
One end of feed pipe 201 is provided with first charging aperture 204, and the other end of feed pipe 201 is provided with the first discharge port
205；Spiral flood dragon 203 is located in feed pipe 201, and spiral flood dragon 203 is arranged along the extending direction of feed pipe 201；Second drives
Dynamic device 202 for driving spiral flood dragon 203 to rotate, the rotation of spiral flood dragon 203 be able to drive material from first charging aperture 204 into
Enter feed pipe 201 and is discharged from the first discharge port 205；Feed pipe 201 is set on support frame.
In this embodiment, feeding mechanism 2 includes feed pipe 201, the second driving device 202, spiral flood dragon 203 and support
Frame；One end of feed pipe 201 is provided with first charging aperture 204, and the other end of feed pipe 201 is provided with the first discharge port 205；Spiral shell
Rotation flood dragon 203 is located in feed pipe 201, and spiral flood dragon 203 extends along the axis direction of feed pipe 201；Second driving device 202
It is disposed in proximity at the first discharge port 205 of feed pipe 201, first driving device 311 can drive spiral flood dragon 203 to rotate；
Material is entered in feed pipe 201 by first charging aperture 204, under the rotary action of 201 inside spin flood dragon 203 of feed pipe, energy
Enough material is driven to move to the first discharge port 205, and is discharged from the first discharge port 205；First discharge port 205 and 3 phase of gelatinization pot
Connection, therefore be able to enter in gelatinization pot 3 by the material that the first discharge port 205 is discharged and carry out mixing gelatinization process.
Wherein, optionally, the second driving device 202 is driving motor, output shaft and the rotation axis of spiral flood dragon 203
One end is connected, and drives the rotation axis rotation of spiral flood dragon 203, so that the flood dragon piece of spiral flood dragon 203 be driven to rotate, and then pushes away
Dynamic material movement.
Wherein, optionally, the raw material cabin 1 of the application is set to underground, and the first charging aperture 204 of feed pipe 201 protrudes into original
In feed bin 1,205 end of the first discharge port of feed pipe 201 is set on support frame, keeps feed pipe 201 and ground angled,
And it is connected with gelatinization pot 3.
It is shown in Figure 2, in one embodiment of the application, it is preferable that be additionally provided with observation window 312 on gelatinization pot 3
And end cap 313；Wherein, observation window 312 is located at 3 top of gelatinization pot, is gelatinized situation for observing the thickener inside gelatinization pot 3；
End cap 313 can be located on observation window 312, for covering observation window 312.
In this embodiment, observation window 312 is additionally provided on gelatinization pot 3, the lid of end cap 313 is located on observation window 312, worker
End cap 313 can be opened at any time to observing in gelatinization pot 3, especially the concrete condition of observable material gelatinization process.Wherein, may be used
Selection of land, observation window 312 are annular structure.
Wherein, optionally, the quantity of observation window 312 can be multiple, and gelatinization pot 3 is comprehensively observed so as to all directions
The gelatinization situation of interior material.
Wherein, optionally, observation window 312 can weld together with gelatinization pot 3.
It is shown in Figure 2, in one embodiment of the application, it is preferable that be additionally provided with installation on the outer wall of gelatinization pot 3
Plate 314 and temperature measuring gauge 315；Mounting plate 314 is connected with the outside wall surface of gelatinization pot 3；Mounting groove is offered on mounting plate 314, is surveyed
Warm table 315 is embedded in mounting groove.
In this embodiment, mounting plate 314 and temperature measuring gauge 315 are additionally provided on the outer wall of gelatinization pot 3, wherein mounting plate
314 one end is connected with the outer surface of gelatinization pot 3, specifically, mounting plate 314 can with gelatinization pot 3 using welding by the way of phase
The other end of connection, mounting plate 314 extends to the direction far from gelatinization pot 3；Mounting groove, temperature measuring gauge are offered on mounting plate 314
315 are embedded in this mounting groove, when being full of hot oil in the storage space of gelatinization pot 3 310, heat can be passed sequentially through gelatinization pot
3 and mounting plate 314 pass to temperature measuring gauge 315, temperature measuring gauge 315 is used to sense the temperature of hot oil, so that staff can be at any time
The temperature for observing hot oil can release hot oil from oil outlet 309, then pour again from oil inlet 308 when temperature is lower than standard
New hot oil.
Embodiments herein additionally provides a kind of excipient substance gelatinizing method, comprising the following steps:
Raw material is entered by feeding mechanism 2 and is delivered in gelatinization pot 3 in step 100, raw material cabin 1；
Heating liquid is added into the storage space of gelatinization pot 3 310 for step 200；
Step 300 opens fluid filling pump, and acid solution is added into gelatinization pot 3 by acid solution filling opening 306；
Step 400 closes fluid filling pump, starting agitating paddle, is uniformly mixed material and acid solution in gelatinization pot 3, and adding
Thickener is obtained under the heat effect of hot liquid；
Step 500, thickener obtained enter thickener storehouse 4；Agitating paddle is closed, being passed through for heating liquid is stopped, completing material
Gelatinization process.
The excipient substance gelatinizing method of the application can be gelatinized equipment by the excipient substance of any of the above-described embodiment and realize.And
High-efficient by above-mentioned gelatinizing method gelatinization, gelatinization uniformly, significantly improves the quality of excipient substance.
Finally, it should be noted that the above embodiments are only used to illustrate the technical solution of the present invention., rather than its limitations；To the greatest extent
Pipe present invention has been described in detail with reference to the aforementioned embodiments, those skilled in the art should understand that: its according to
So be possible to modify the technical solutions described in the foregoing embodiments, or to some or all of the technical features into
Row equivalent replacement；And these are modified or replaceed, various embodiments of the present invention technology that it does not separate the essence of the corresponding technical solution
The range of scheme.
Claims (10)
1. a kind of excipient substance is gelatinized equipment characterized by comprising raw material cabin, feeding mechanism, gelatinization pot and thickener storehouse；
One end of the feeding mechanism is connected with the raw material cabin, and the other end of the feeding mechanism and the gelatinization pot are fed
Mouth is connected；The gelatinization pot discharge port is connected with the thickener storehouse；
Agitating paddle, folding flitch and Vibration Box are provided in the gelatinization pot；The agitating paddle is placed in the gelatinization pot for stirring
Thickener；One end of the folding flitch is connected with the inner sidewall of the gelatinization pot, for making close to the gelatinization pot inner wall
Thickener it is mobile towards the agitating paddle；The Vibration Box is located at the gelatinization pot bottom, for making bottom in the gelatinization pot
Thickener concussion is uniform；
The gelatinization pot is double-layer structure, forms storage space between the double-layer structure of the gelatinization pot, for storing heating liquid
Body.
2. excipient substance according to claim 1 is gelatinized equipment, which is characterized in that the gelatinization pot upper end is additionally provided with acid
Liquid filling opening, the acid solution filling opening are connected by fluid filling pump with acid solution tank, for acid solution to be added into the gelatinization pot.
3. excipient substance according to claim 1 is gelatinized equipment, which is characterized in that the folding flitch include connecting rod and
Scraping wings；One end of the connecting rod is connected with the interior sidewall surface of the gelatinization pot, the other end of the connecting rod with it is described
Scraping wings is connected；The axis of the scraping wings and the gelatinization pot is arranged in angle.
4. excipient substance according to claim 1 is gelatinized equipment, which is characterized in that the agitating paddle include stirring rod and
Paddle；It is provided with first driving device outside the gelatinization pot, the first driving device is connected with the stirring rod, is used for
The stirring rod is driven to rotate；The paddle is arranged on the stirring rod；The quantity of the paddle is multiple, Duo Gesuo
Paddle is stated along the circumferentially staggered distribution of the stirring rod.
5. excipient substance according to claim 1 is gelatinized equipment, which is characterized in that the Vibration Box and supersonic generator phase
Connection；The quantity of the Vibration Box be it is multiple, multiple Vibration Boxes are uniformly distributed in bottom in the gelatinization pot.
6. excipient substance according to claim 1 is gelatinized equipment, which is characterized in that be provided with humidity discharging on the gelatinization pot
Mouth, oil inlet and oil outlet；Wherein, the humidity discharging mouth is located at the top of the gelatinization pot, for being discharged in the gelatinization pot
Moisture；The oil inlet is located at gelatinization pot outside wall surface lower part, and the oil outlet is located at gelatinization pot outside wall surface top, institute
It states oil inlet and the oil outlet is connected with the storage space respectively；The oil inlet is for conveying liquid to the storage
In space, the oil outlet is used for the liquid being discharged in the storage space.
7. excipient substance according to claim 1 is gelatinized equipment, which is characterized in that the feeding mechanism includes feeding
Pipe, the second driving device, spiral flood dragon and support frame；
One end of the feed pipe is provided with first charging aperture, and the other end of the feed pipe is provided with the first discharge port；It is described
Spiral flood dragon is located in the feed pipe, and the spiral flood dragon is arranged along the extending direction of the feed pipe；Described second drives
Dynamic device for driving the spiral flood dragon to rotate, the spiral flood dragon rotation be able to drive material from the first charging aperture into
Enter the feed pipe and is discharged from first discharge port；The feed pipe is set on support frame as described above.
8. excipient substance according to claim 1 is gelatinized equipment, which is characterized in that be additionally provided with observation on the gelatinization pot
Window and end cap；Wherein, the observation window is located at the top of the gelatinization pot, for observing the thickener gelatinization inside the gelatinization pot
Situation；The end cap can be located on the observation window, for covering the observation window.
9. excipient substance according to claim 1 is gelatinized equipment, which is characterized in that also set up on the outer wall of the gelatinization pot
There are mounting plate and temperature measuring gauge；The mounting plate is connected with the outside wall surface of the gelatinization pot；Installation is offered on the mounting plate
Slot, the temperature measuring gauge are embedded in the mounting groove.
10. a kind of excipient substance gelatinizing method, which comprises the following steps:
Raw material is entered by feeding mechanism and is delivered in gelatinization pot in step 100, raw material cabin；
Heating liquid is added into the storage space of the gelatinization pot for step 200；
Step 300 opens fluid filling pump, and acid solution is added into the gelatinization pot by acid solution filling opening；
Step 400 closes fluid filling pump, starting agitating paddle, is uniformly mixed material and acid solution in the gelatinization pot, and heating
Thickener is obtained under the heat effect of liquid；
Step 500, thickener obtained enter thickener storehouse；Agitating paddle is closed, being passed through for heating liquid is stopped, material is completed and was gelatinized
Journey.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201811117830.7A CN108970521A (en) | 2018-09-25 | 2018-09-25 | Excipient substance is gelatinized equipment and excipient substance gelatinizing method |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201811117830.7A CN108970521A (en) | 2018-09-25 | 2018-09-25 | Excipient substance is gelatinized equipment and excipient substance gelatinizing method |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN108970521A true CN108970521A (en) | 2018-12-11 |
Family
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201811117830.7A Pending CN108970521A (en) | 2018-09-25 | 2018-09-25 | Excipient substance is gelatinized equipment and excipient substance gelatinizing method |
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| Country | Link |
|---|---|
| CN (1) | CN108970521A (en) |
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| WO2020199716A1 (en) * | 2019-04-02 | 2020-10-08 | 浙江迦南科技股份有限公司 | Pulp mixing device |
| CN113744924A (en) * | 2021-08-24 | 2021-12-03 | 深圳市宏技欣塑胶电子有限公司 | Electric wire and preparation method thereof |
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