CN108956721A - A kind of stool occult blood detector chemicals - Google Patents
A kind of stool occult blood detector chemicals Download PDFInfo
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- CN108956721A CN108956721A CN201710352229.5A CN201710352229A CN108956721A CN 108956721 A CN108956721 A CN 108956721A CN 201710352229 A CN201710352229 A CN 201710352229A CN 108956721 A CN108956721 A CN 108956721A
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- occult blood
- blood detector
- stool
- stool occult
- carbon electrode
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
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- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
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- Molecular Biology (AREA)
- Analytical Chemistry (AREA)
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- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
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- Investigating Or Analysing Biological Materials (AREA)
Abstract
The present invention relates to a kind of stool occult blood detector chemicals.The invention belongs to stool occult blood detection technique fields.It is characterized in that: stool occult blood detector chemicals includes the buffer solution for mixing stool sample, and the carbon electrode component reacted methyl biphenyl amine occurs for a kind of stool occult blood detector chemicals；Buffer solution group becomes the Proclin (electrode preservative) of 0.08-0.12M citric acid, 0.8-1.2M potassium chloride, 0.006-0.012M saponin, 0.17-0.25M disodium hydrogen phosphate and 0.045-0.052% volume ratio；Carbon electrode constituent mass percentage is 3,3 ', 5,5 '-to methyl biphenyl amine 7-9.2%, monohydrate sodium stannate 5-7%, graphite powder 54-57% and paraffin oil 28-32%.The present invention has detection quick, and data are accurate, and sensibility is high, and component is simple, and quality is stablized, securely and reliably, the advantages that having a wide range of application.
Description
Technical field
The invention belongs to stool occult blood detection technique fields, more particularly to a kind of stool occult blood detector chemicals.
Background technique
Stool occult blood detection is colorectal cancer census method international at present, is that American Cancer Society (ACS) is recommended extensively
" the routine inspection project of healthy population physical examination ".Stool occult blood inspection can be used as detection a variety of causes caused by hemorrhage of digestive tract and
The important detection of malignant tumor of digestive tract early screening is tested.
Currently, digestive system tumor morbidity account for malignant tumour always fall ill number more than half.Wherein colorectal cancer is in malignant tumour
It is number three in disease incidence.Portable and quick diagnosis purpose may be implemented using detector, can effectively help to monitor enteron aisle
Health.Existing stool occult blood detector product, it is convenient to have -- and compact, easy to use, completely ,-sample collection process is clear
The features such as clean health, easily operated secret.But that there is also the sensibility of buffer solution and carbon electrode component is poor, specificity is bad,
Detection accuracy is low, cannot be applicable in the technical problems such as more stool occult blood detector.
Summary of the invention
The present invention is to solve technical problem present in well-known technique and provide a kind of stool occult blood detector chemicals.
The object of the present invention is to provide one kind to have detection quick, and data are accurate, and sensibility is high, and component is simple, and quality is steady
Calmly, securely and reliably, the stool occult blood detector chemicals for the features such as having a wide range of application.
Working principle of the present invention: if containing hemorrhage of digestive tract in fecal specimens, after it is inserted into kit, hemoglobin
It will be released in buffer.Electrochemical signals sensor in kit can pass through methyl in hemoglobin and sensor
Hemoglobin in benzidine and perborate reaction detection buffer exists, and realizes stool occult blood testing goal.
Stool occult blood detector chemicals of the present invention is adopted the technical scheme that:
A kind of stool occult blood detector chemicals, its main feature is that: stool occult blood detector chemicals includes mixing stool sample
The buffer solution of product, and the carbon electrode component reacted methyl biphenyl amine occurs；Buffer solution group becomes 0.08-0.12M lemon
Lemon acid, 0.8-1.2M potassium chloride, 0.006-0.012M saponin, 0.17-0.25M disodium hydrogen phosphate and 0.045-0.052% body
The Proclin (electrode preservative) of product ratio；Carbon electrode constituent mass percentage is 3,3 ', 5,5 '-to methyl biphenyl amine 7-
9.2%, monohydrate sodium stannate 5-7%, graphite powder 54-57% and paraffin oil 28-32%.
Stool occult blood detector chemicals of the present invention can also adopt the following technical scheme that
The stool occult blood detector chemicals, its main feature is that: stool occult blood detector is attached separately to reagent with chemicals
In box, the volume of buffer is 1.5-2ml in each kit, and carbon electrode group is divided into 200-300 μ g in each kit.
The stool occult blood detector chemicals, its main feature is that: the graphite powder diameter of carbon electrode is less than 20 μm.
The advantages and positive effects of the present invention are:
Stool occult blood detector chemicals is due to using the completely new technical solution of the present invention, compared with prior art, this
Invention detection is quick, and data are accurate, and sensibility is high, and component is simple, and quality is stablized, securely and reliably, the advantages that having a wide range of application.
Specific embodiment
In order to further understand the content, features and effects of the present invention, the following examples are hereby given, it is described in detail such as
Under:
Embodiment 1
A kind of stool occult blood detector chemicals, the buffer solution including mixing stool sample, and occur to join methyl
The carbon electrode component of aniline reaction；Buffer solution group becomes 0.1M citric acid, 1M potassium chloride, 0.01M saponin, 0.2M phosphoric acid hydrogen
The electrode corrosion-resistant agent Proclin300 of disodium and 0.049% volume ratio；Carbon electrode constituent mass percentage is 3,3 ', 5,5 '-right
Methyl biphenyl amine 8.5%, monohydrate sodium stannate 6%, graphite powder 55.5% (diameter is less than 20 μm) and paraffin oil 30%.
Stool occult blood detector is attached separately in kit with chemicals, and the volume of buffer is 1.6ml in each kit,
Carbon electrode group is divided into 250 μ g in each kit.
The test process of the present embodiment:
When the present embodiment stool occult blood detector is tested, the carbon electrode containing chemical component is housed on each sampler barrel.It is testing
During stool sample mixed with buffer solution after react with carbon electrode to methyl biphenyl amine.
When test, if containing hemorrhage of digestive tract in fecal specimens, after it is inserted into kit, hemoglobin will be released
It is put into buffer.Electrochemical signals sensor in kit can by methyl biphenyl amine in hemoglobin and sensor and
Hemoglobin in perborate reaction detection buffer exists, and reaches stool occult blood testing goal of the present invention.
The present embodiment has the detection quick, and data are accurate, and sensibility is high, and component is simple, and quality is stablized, and safely may be used
It leans on, have a wide range of application equal good effects.
Claims (3)
1. a kind of stool occult blood detector chemicals, it is characterized in that: stool occult blood detector chemicals includes mixing stool sample
Buffer solution, and the carbon electrode component reacted methyl biphenyl amine occurs；Buffer solution group becomes 0.08-0.12M lemon
Acid, 0.8-1.2M potassium chloride, 0.006-0.012M saponin, 0.17-0.25M disodium hydrogen phosphate and 0.045-0.052% volume
The Proclin of ratio；Carbon electrode constituent mass percentage is 3,3 ', 5,5 '-to methyl biphenyl amine 7-9.2%, monohydrate sodium stannate
5-7%, graphite powder 54-57% and paraffin oil 28-32%.
2. stool occult blood detector chemicals according to claim 1, it is characterized in that: stool occult blood detector chemicals point
Zhuan not be in kit, the volume of buffer is 1.5-2ml in each kit, and carbon electrode group is divided into each kit
200-300 μ g.
3. stool occult blood detector chemicals according to claim 1 or 2, it is characterized in that: the graphite powder diameter of carbon electrode
Less than 20 μm.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710352229.5A CN108956721A (en) | 2017-05-18 | 2017-05-18 | A kind of stool occult blood detector chemicals |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710352229.5A CN108956721A (en) | 2017-05-18 | 2017-05-18 | A kind of stool occult blood detector chemicals |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN108956721A true CN108956721A (en) | 2018-12-07 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201710352229.5A Pending CN108956721A (en) | 2017-05-18 | 2017-05-18 | A kind of stool occult blood detector chemicals |
Country Status (1)
| Country | Link |
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| CN (1) | CN108956721A (en) |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4673654A (en) * | 1985-10-31 | 1987-06-16 | Warner-Lambert Company | Composition for determining peroxidase-like activity of hemoglobin |
| US20090240130A1 (en) * | 2008-03-18 | 2009-09-24 | Barnes Sr Albert T | Examination Device for Blood Detection |
| CN102282468A (en) * | 2008-11-13 | 2011-12-14 | 模式诊断有限公司 | Electrode, electrochemical sensor and apparatus, and methods for operating the same |
| CN104854456A (en) * | 2012-10-16 | 2015-08-19 | 模式诊断有限公司 | Immunoassay using electrochemical detection |
| US20160047824A1 (en) * | 2012-11-12 | 2016-02-18 | Mode Diagnostics Limited | Personal test device |
-
2017
- 2017-05-18 CN CN201710352229.5A patent/CN108956721A/en active Pending
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4673654A (en) * | 1985-10-31 | 1987-06-16 | Warner-Lambert Company | Composition for determining peroxidase-like activity of hemoglobin |
| US20090240130A1 (en) * | 2008-03-18 | 2009-09-24 | Barnes Sr Albert T | Examination Device for Blood Detection |
| CN102282468A (en) * | 2008-11-13 | 2011-12-14 | 模式诊断有限公司 | Electrode, electrochemical sensor and apparatus, and methods for operating the same |
| CN104854456A (en) * | 2012-10-16 | 2015-08-19 | 模式诊断有限公司 | Immunoassay using electrochemical detection |
| US20160047824A1 (en) * | 2012-11-12 | 2016-02-18 | Mode Diagnostics Limited | Personal test device |
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| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20181207 |