CN108938611A - New humans and animals antibiotic Tris Nitro and trishydroxymethylaminomethane and its esters - Google Patents

New humans and animals antibiotic Tris Nitro and trishydroxymethylaminomethane and its esters Download PDF

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Publication number
CN108938611A
CN108938611A CN201710365996.XA CN201710365996A CN108938611A CN 108938611 A CN108938611 A CN 108938611A CN 201710365996 A CN201710365996 A CN 201710365996A CN 108938611 A CN108938611 A CN 108938611A
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CN
China
Prior art keywords
trishydroxymethylaminomethane
esters
animals
humans
tris nitro
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Pending
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CN201710365996.XA
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Chinese (zh)
Inventor
邹小中
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Individual
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Individual
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Publication date
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Priority to CN201710365996.XA priority Critical patent/CN108938611A/en
Publication of CN108938611A publication Critical patent/CN108938611A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/133Amines having hydroxy groups, e.g. sphingosine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/045Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/047Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates having two or more hydroxy groups, e.g. sorbitol
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

The invention belongs to new humans and animals antibiotic; Tris Nitro and trishydroxymethylaminomethane and its esters have simple carbon symmetrical structure and three high response hydroxyls; it can infiltrate through intracellular; there is protective effect to multicellular organism cell under a certain concentration, there is extremely strong killing and inhibiting effect to unicellular organism and microorganism.Tris Nitro and trishydroxymethylaminomethane and its esters can replace existing antibiotic for treating the humans and animals of Infective helminth pathogenic microorganisms.With easy to implement.

Description

New humans and animals antibiotic Tris Nitro and trihydroxy methyl amino Methane and its esters
Technical field: the invention belongs to antibiotic medicine, especially new broad-spectrum high efficacy safely and fast antibiotic.Belong to doctor Treatment and pharmaceutical field.
Background technique: usual Tris Nitro is as lifeless object disinfectant.It is mainly used for following Industrial water system is cut in disappear oil, non-protein glue and slurry, to inhibit bacterial reproduction;Trishydroxymethylaminomethane is as alkalinity Drug is served only for the correction of acid poisoning, and the salt of trishydroxymethylaminomethane also only cooks buffer, they are not yet as anti- Raw element is used for humans and animals.For humans and animals infection helminth, pathogenic microorganisms be all at present using different antibiotic and Other medicines are treated, for AIDS, hepatopathy virus etc. not yet specific drug, acute appendicitis based on operative treatment, The common drugs such as epididymis, prostate are difficult to reach, and mycoplasma, Chlamydia common drug curative effect are also bad.
Simple carbon symmetrical structure that Tris Nitro and trishydroxymethylaminomethane and its esters have and Three high response hydroxyls can infiltrate through into the cell, have protective effect to multicellular organism cell under a certain concentration, to slender Born of the same parents' biology and microorganism have extremely strong tag and inhibiting effect.It is especially former to superbacteria, comma bacillus, mycoplasma, clothing Body, AIDS virus, hepatopathy virus have special efficacy.The therapeutic effects such as the epididymitis reached, prostatitis are difficult to for common drug Well.Ecphyaditis is even more that As the medicine took effect, the symptoms lessened, does not have to operation.
Summary of the invention: with Tris Nitro and trishydroxymethylaminomethane and its esters, humans and animals are treated Infect helminth, pathogenic microorganisms.Superbacteria, comma bacillus, mycoplasma, Chlamydia, AIDS disease are infected for treating people Poison, hepatopathy virus, unicellular parasite.For treating epididymitis, prostatitis, ecphyaditis.
Tris Nitro molecular formula: C4H9NO5
Tris Nitro relative molecular weight: 151.12
Tris Nitro structural formula:
Trishydroxymethylaminomethane molecular formula: C4H11NO3
Trishydroxymethylaminomethane relative molecular weight: 121.14
Trishydroxymethylaminomethane structural formula:
Specific embodiment: dosage, direct mouth are determined by the helminth and microbe species of humans and animals weight and infection Clothes or injection, immersion etc..

Claims (1)

1. new humans and animals antibiotic Tris Nitro and trishydroxymethylaminomethane and its esters, for controlling It treats humans and animals and infects helminth, pathogenic microorganisms.Superbacteria, comma bacillus, mycoplasma, clothing original are infected for treating people Body, AIDS virus, hepatopathy virus, unicellular parasite.For treating epididymitis, prostatitis, ecphyaditis.
CN201710365996.XA 2017-05-17 2017-05-17 New humans and animals antibiotic Tris Nitro and trishydroxymethylaminomethane and its esters Pending CN108938611A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201710365996.XA CN108938611A (en) 2017-05-17 2017-05-17 New humans and animals antibiotic Tris Nitro and trishydroxymethylaminomethane and its esters

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201710365996.XA CN108938611A (en) 2017-05-17 2017-05-17 New humans and animals antibiotic Tris Nitro and trishydroxymethylaminomethane and its esters

Publications (1)

Publication Number Publication Date
CN108938611A true CN108938611A (en) 2018-12-07

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
CN201710365996.XA Pending CN108938611A (en) 2017-05-17 2017-05-17 New humans and animals antibiotic Tris Nitro and trishydroxymethylaminomethane and its esters

Country Status (1)

Country Link
CN (1) CN108938611A (en)

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6538155B1 (en) * 1999-03-03 2003-03-25 Steven A. Melman Method for preparing an EDTA-Tris composition, a composition containing EDTA-Tris and uses therefor
CN101849547A (en) * 2010-06-04 2010-10-06 内蒙古天晨科技有限责任公司 High-efficiency fungicide
CN102524268A (en) * 2010-11-18 2012-07-04 陶氏环球技术有限公司 Synergistic antimicrobial composition comprising 1,2-benzisothiazolin-3-one and tris(hydroxymethyl)nitromethane

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6538155B1 (en) * 1999-03-03 2003-03-25 Steven A. Melman Method for preparing an EDTA-Tris composition, a composition containing EDTA-Tris and uses therefor
CN101849547A (en) * 2010-06-04 2010-10-06 内蒙古天晨科技有限责任公司 High-efficiency fungicide
CN102524268A (en) * 2010-11-18 2012-07-04 陶氏环球技术有限公司 Synergistic antimicrobial composition comprising 1,2-benzisothiazolin-3-one and tris(hydroxymethyl)nitromethane

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
顾学裘主编, 人民卫生出版社 *

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Application publication date: 20181207