CN108926356A - Detector photon reaches information and determines method, apparatus and Medical Devices - Google Patents

Detector photon reaches information and determines method, apparatus and Medical Devices Download PDF

Info

Publication number
CN108926356A
CN108926356A CN201810553188.0A CN201810553188A CN108926356A CN 108926356 A CN108926356 A CN 108926356A CN 201810553188 A CN201810553188 A CN 201810553188A CN 108926356 A CN108926356 A CN 108926356A
Authority
CN
China
Prior art keywords
pixel
real
adjacent
virtual
photon
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CN201810553188.0A
Other languages
Chinese (zh)
Other versions
CN108926356B (en
Inventor
杨鹏
李晓超
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Shanghai United Imaging Healthcare Co Ltd
Original Assignee
Shanghai United Imaging Healthcare Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shanghai United Imaging Healthcare Co Ltd filed Critical Shanghai United Imaging Healthcare Co Ltd
Priority to CN201810553188.0A priority Critical patent/CN108926356B/en
Publication of CN108926356A publication Critical patent/CN108926356A/en
Application granted granted Critical
Publication of CN108926356B publication Critical patent/CN108926356B/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment
    • A61B6/42Arrangements for detecting radiation specially adapted for radiation diagnosis
    • A61B6/4208Arrangements for detecting radiation specially adapted for radiation diagnosis characterised by using a particular type of detector
    • A61B6/4241Arrangements for detecting radiation specially adapted for radiation diagnosis characterised by using a particular type of detector using energy resolving detectors, e.g. photon counting

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medical Informatics (AREA)
  • Engineering & Computer Science (AREA)
  • Radiology & Medical Imaging (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Optics & Photonics (AREA)
  • Pathology (AREA)
  • Physics & Mathematics (AREA)
  • High Energy & Nuclear Physics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Molecular Biology (AREA)
  • Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Apparatus For Radiation Diagnosis (AREA)

Abstract

Information, which is reached, this application involves a kind of detector photon determines method, apparatus, Medical Devices and storage medium.The method includes:A virtual pixel is constructed between the adjacent real pixel of any preset quantity;When the signal amplitude of the virtual pixel is more than given threshold, the pixel centered on the acquisition maximum real pixel of signal amplitude in the adjacent real pixel and real pixel adjacent thereto of the preset quantity, using the position of the center pixel as photon in-position.The position that photon reaches can accurately be determined using this method, eliminate the interference of the electron cloud of photon generation, determine photon in-position more accurate, further can be improved image quality.

Description

Detector photon reaches information and determines method, apparatus and Medical Devices
Technical field
This application involves technical field of medical equipment, more particularly to a kind of detector photon reach information determine method, Device, Medical Devices and storage medium.
Background technique
As the development of Medical Devices technology improves CT quantitative analysis, photon counting to reduce the dose of radiation of patient Power spectrum CT technology is come into being.Photon counting power spectrum CT has material composition analytic function, and having can be reduced suffered by patient Radiation the advantages that.Develop photon counting power spectrum CT, has become domestic and international academia and the next generation that industry is paid close attention to jointly One of CT developing direction.X-ray sub-count detector (PCD) technology is the key that restrict photon counting power spectrum CT development.
In current traditional technology, in order to improve spatial resolution and meet clinical count requirement, X-ray sub-count detector Pixel (pixel) size generally only have several hundred microns (100-300 μm).When detector pixel size is smaller, X-ray is produced Raw electron cloud may lead to the photon in-position for the photon collected by detector collected by adjacent detector pixel And photon arrival time by mistake judgement, and then influence image quality.
Summary of the invention
Based on this, it is necessary in view of the above technical problems, provide a kind of spy that can accurately determine photon in-position It surveys device photon arrival information and determines method, apparatus, Medical Devices and storage medium.
A kind of detector photon reaches information and determines method, the method includes:In the adjacent true of any preset quantity A virtual pixel is constructed between real image element;When the signal amplitude of the virtual pixel is more than given threshold, described default In the adjacent real pixel and real pixel adjacent thereto of quantity centered on the acquisition maximum real pixel of signal amplitude Pixel, using the position of the center pixel as photon in-position.
One in the adjacent real pixel of the virtual pixel and the preset quantity in one of the embodiments, With corresponding relationship;It is described when the signal amplitude of the virtual pixel be more than given threshold when, in the adjacent of the preset quantity Real pixel and real pixel adjacent thereto in obtain pixel centered on the maximum real pixel of signal amplitude, will be described The position of center pixel as photon in-position, including:It, will when the signal amplitude of the virtual pixel is more than given threshold With real pixel of the virtual pixel with corresponding relationship and the phase centered on the real pixel with corresponding relationship Adjacent multiple real pixels send request instruction as pixel to be compared, to the pixel to be compared;According to the request instruction point The pixel to be compared real pixel adjacent thereto is not compared, the maximum real pixel of wherein signal amplitude is obtained and makees For corresponding region center pixel;Multiple regions center pixel is compared, the maximum real pixel of wherein signal amplitude is obtained Centered on pixel, using the position of the center pixel as photon in-position.
The preset quantity is four in one of the embodiments,;The right side of the virtual pixel and the virtual pixel Real pixel at lower position has corresponding relationship.
The signal of the virtual pixel is the adjacent real pixel of the preset quantity in one of the embodiments, Signal averaging.
It is described in one of the embodiments, to there is the real pixel of corresponding relationship and with the virtual pixel with described Adjacent multiple real pixels centered on real pixel with corresponding relationship as pixel to be compared, including:It will be with the void Intend real pixel of the pixel with corresponding relationship and adjacent eight centered on the real pixel with corresponding relationship true Real image element is as pixel to be compared.
It is described respectively that the pixel to be compared is adjacent thereto according to the request instruction in one of the embodiments, Real pixel is compared, including:According to the request instruction by the pixel to be compared it is independent with its own on, upper left, Left and lower-left four real pixels are compared.
In one of the embodiments, the method also includes:The threshold time of crossing of the virtual pixel is labeled as photon Arrival time.
A kind of detector photon arrival information determining means, described device include:Virtual pixel constructs module, in office A virtual pixel is constructed between the adjacent real pixel for preset quantity of anticipating;Photon in-position determining module, for working as institute When stating the signal amplitude of virtual pixel and being more than given threshold, in the adjacent real pixel of the preset quantity and adjacent thereto Pixel centered on the acquisition maximum real pixel of signal amplitude in real pixel, using the position of the center pixel as photon In-position.
A kind of Medical Devices, including memory and processor, the memory are stored with computer program, the processor Following steps are realized when executing the computer program:
A virtual pixel is constructed between the adjacent real pixel of any preset quantity;
When the signal amplitude of the virtual pixel is more than given threshold, in the adjacent real pixel of the preset quantity With in real pixel adjacent thereto obtain the maximum real pixel of signal amplitude centered on pixel, by the center pixel Position is as photon in-position.
A kind of computer readable storage medium, is stored thereon with computer program, and the computer program is held by processor Following steps are realized when row:
A virtual pixel is constructed between the adjacent real pixel of any preset quantity;
When the signal amplitude of the virtual pixel is more than given threshold, in the adjacent real pixel of the preset quantity With in real pixel adjacent thereto obtain the maximum real pixel of signal amplitude centered on pixel, by the center pixel Position is as photon in-position.
Above-mentioned detector photon reaches information and determines method, apparatus, Medical Devices and storage medium, by arbitrarily default Simulation pixel is constructed between the adjacent real pixel of quantity, when the signal amplitude of simulation pixel is more than given threshold, in structure Pixel centered on the real pixel for obtaining amplitude maximum is built in the real pixel real pixel adjacent with its of virtual pixel, The position of middle center pixel is photon in-position.By comparing the signal amplitude of multiple real pixels, and by amplitude maximum Real pixel position is as photon in-position.It can accurately determine the position that photon reaches, eliminate the electricity of photon generation The interference of sub- cloud determines photon in-position more accurate, further can be improved image quality.
Detailed description of the invention
Fig. 1 is that detector photon reaches the flow diagram that information determines method in one embodiment;
Fig. 2 is that detector photon reaches the flow diagram that information determines method in another embodiment;
Fig. 3 is that detector photon reaches the flow diagram that information determines method in another embodiment;
Fig. 4 is real pixel and virtual pixel schematic diagram in one embodiment;
Fig. 5 is that the photon arrival information that a real pixel receives photon in one embodiment determines schematic diagram;
Fig. 6 is that the photon arrival information that multiple real pixels receive photon in one embodiment determines schematic diagram;
Fig. 7 is the structural block diagram that detector photon reaches information determining means in one embodiment;
Fig. 8 is the structural block diagram of photon in-position determining module in one embodiment;
Fig. 9 is the internal structure chart of Medical Devices in one embodiment.
Appended drawing reference:100 be detector photon reach information determining means, 110 be virtual pixel building module, 120 be Photon in-position determining module, 121 be corresponding relationship determination unit, 122 be pixel value determining unit to be compared, 123 be to compare Unit, 124 be photon in-position determination unit, 130 be photon arrival time determining module.
Specific embodiment
It is with reference to the accompanying drawings and embodiments, right in order to which the objects, technical solutions and advantages of the application are more clearly understood The application is further elaborated.It should be appreciated that specific embodiment described herein is only used to explain the application, not For limiting the application.
In one embodiment, method is determined as shown in Figure 1, providing a kind of detector photon and reaching information, including with Lower step:
Step S102 constructs a virtual pixel between the adjacent real pixel of any preset quantity.
Specifically, the ray detector in Medical Devices is a kind of device that the energy of ray is converted to electric signal.It visits It surveys device and receives radiation exposure, and the radiation intensity of ray is converted into electric signal, Medical Devices generate image by electric signal. Wherein detector is made of multiple real pixels.Wherein each real pixel can receive radiation exposure, and by ray Radiation intensity be converted into electric signal.The virtual representation that virtual pixel constructs between the adjacent real pixel of any preset quantity Element, the wherein real pixel of preset quantity adjacent formation rectangle two-by-two.
Step S104, when the signal amplitude of virtual pixel is more than given threshold, in the adjacent true picture of preset quantity Pixel centered on the acquisition maximum real pixel of signal amplitude in plain and adjacent thereto real pixel, by the position of center pixel It sets as photon in-position.
Specifically, the signal of real pixel is the electric signal that the radiation intensity of ray is converted by real pixel.Virtual representation The signal of element is the Signal averaging of the adjacent real pixel of preset quantity.Namely the preset quantity of building virtual pixel is true The superposition of the electric signal of pixel.By the way that virtual pixel signal threshold value appropriate is arranged, it can accurately determine that ray photons reach The time of real pixel carries out the determination of position again in correct time, and the determination of position can be made more accurate.Work as void When the signal amplitude of quasi- pixel is more than given threshold, that is, in the moment of ray photons arrival real pixel, constructing virtually In the real pixel of the pixel real pixel adjacent with its, pixel centered on the maximum real pixel of signal amplitude is searched, in The position of imago element is exactly the in-position of photon.
Above-mentioned detector photon reaches information and determines in method, in true adjacent with its of the real pixel of building virtual pixel In real image element, in-position of the position of the maximum real pixel of signal amplitude as photon is searched.Real pixel is receiving light The photon cloud that son is formed generates electric signal, since the electron cloud that photon is formed may be absorbed by multiple real pixels simultaneously, and The position of the real pixel of amplitude maximum in multiple real pixels is chosen as photon in-position, the arrival position of photon can be made It sets determining more accurate.
In one embodiment, method is determined as shown in Fig. 2, providing a kind of detector photon and reaching information, including with Lower step:
Step S202 constructs a virtual pixel between the adjacent real pixel of any preset quantity.
Specifically, the matrix that the detector of Medical Devices is made of multiple real pixels.Wherein each real pixel Radiation exposure can be received, and the radiation intensity of ray is converted into electric signal.Virtual pixel is the phase of any preset quantity The virtual pixel constructed between adjacent real pixel, the wherein real pixel of preset quantity adjacent formation rectangle two-by-two.
Virtual pixel is crossed threshold time label when the signal amplitude of virtual pixel is more than given threshold by step S204 For photon arrival time.
Specifically, real pixel receives radiation exposure, and the radiation intensity of ray is converted into electric signal.It will construct virtual The signal of the real pixel of the preset quantity of pixel is overlapped, and obtains the signal of virtual pixel.And utilize the letter of virtual pixel Number amplitude judges that ray photons reach the time of real pixel.When the signal of virtual pixel is more than preset threshold value, then It will be more than the time of given threshold as photon arrival time.
Step S206 obtains signal amplitude in the adjacent real pixel and real pixel adjacent thereto of preset quantity Pixel centered on maximum real pixel, using the position of center pixel as photon in-position.
Specifically, when the signal amplitude of virtual pixel is more than given threshold, and marking the signal of virtual pixel is more than threshold value Time be photon arrival time after, in the real pixel real pixel adjacent with its of building virtual pixel, lookup signal The position of pixel centered on the real pixel of amplitude maximum, center pixel is exactly the in-position of photon.
Above-mentioned detector photon reaches information and determines in method, and the signal for constructing the real pixel of virtual pixel is folded Add the signal for obtaining virtual pixel, is determined to make photon arrival time using the signal progress photon arrival time of virtual pixel Determination it is more accurate.When the signal of virtual pixel is more than threshold value, the signal of real pixel is also in rising edge at this time, when When the signal of virtual pixel compares more than the signal for carrying out real pixel after threshold value, the signal of real pixel reaches amplitude at this time, It ensure that the accuracy of comparison result, determination photon arrival time that can be more accurate and photon in-position.
In one embodiment, method, virtual representation are determined as shown in figure 3, providing a kind of detector photon and reaching information Element can be with any one in the real pixel of building virtual pixel with corresponding relationship.Specifically can be:Virtual pixel There is corresponding relationship with the real pixel at the bottom-right location of virtual pixel;At the upper-right position of virtual pixel and virtual pixel Real pixel has corresponding relationship;The real pixel of the lower left position of virtual pixel and virtual pixel has corresponding relationship;It is empty Real pixel at quasi- pixel and the top-left position of virtual pixel has corresponding relationship.Wherein corresponding relationship is for determining that photon arrives When up to position, the real pixel to virtual pixel with corresponding relationship and the phase centered on the real pixel with corresponding relationship Adjacent multiple real pixels send request instruction.Detector photon reaches information and determines that method includes the following steps:
Step S302 constructs a virtual pixel between the adjacent real pixel of any preset quantity.
Specifically, the ray detector in Medical Devices is a kind of device that the energy of ray is converted to electric signal.It visits It surveys device and receives radiation exposure, and the radiation intensity of ray is converted into electric signal, Medical Devices generate image by electric signal. The wherein matrix that detector is made of multiple real pixels.Wherein each real pixel can receive radiation exposure, and The radiation intensity of ray is converted into electric signal.What virtual pixel constructed between the adjacent real pixel of any preset quantity Virtual pixel.More specifically, preset quantity is four, that is, virtual pixel is the adjacent real pixel building of any four Virtual pixel.The wherein real pixel of preset quantity adjacent formation rectangle namely four adjacent two two-phases of real pixel two-by-two Neighbour surrounds rectangle.
Virtual pixel is crossed threshold time label when the signal amplitude of virtual pixel is more than given threshold by step S304 For photon arrival time, and by the real pixel with virtual pixel with corresponding relationship and with the real pixel with corresponding relationship Centered on adjacent multiple real pixels as pixel to be compared, send request instruction to pixel to be compared.
Specifically, real pixel receives radiation exposure, and the radiation intensity of ray is converted into electric signal.It will construct virtual The signal of the real pixel of the preset quantity of pixel is overlapped, and obtains the signal of virtual pixel.And utilize the letter of virtual pixel Number amplitude judges that ray photons reach the time of real pixel.When the signal of virtual pixel is more than preset threshold value, then It will be more than the time of given threshold as photon arrival time.It, will when the signal of virtual pixel is more than preset threshold value Real pixel with virtual pixel with corresponding relationship and adjacent true centered on the real pixel with corresponding relationship Pixel sends request instruction as pixel to be compared, to pixel to be compared.
Wherein the adjacent real pixel centered on the real pixel with corresponding relationship be with corresponding relationship Adjacent eight real pixel centered on real pixel.More specifically can be:When the bottom right of virtual pixel and virtual pixel When real pixel at position has corresponding relationship, by eight adjacent with its of the real pixel at the bottom-right location of virtual pixel Real pixel is as pixel to be compared;Real pixel at the upper-right position of virtual pixel and virtual pixel has corresponding relationship When, eight real pixels that the real pixel at the upper-right position of virtual pixel is adjacent with its are as pixel to be compared;Work as void When the real pixel of the lower left position of quasi- pixel and virtual pixel has corresponding relationship, by the lower left position of virtual pixel Real pixel eight real pixels adjacent with its are as pixel to be compared;At the top-left position of virtual pixel and virtual pixel Real pixel have corresponding relationship when, by the eight true pictures adjacent with its of the real pixel at the top-left position of virtual pixel Element is used as pixel to be compared.Request instruction is for controlling each pixel to be compared for the signal of current real pixel and adjacent true The signal of real image element is compared.
Pixel to be compared real pixel adjacent thereto is compared respectively according to request instruction, obtains by step S306 Wherein the maximum real pixel of signal amplitude is as corresponding region center pixel.
Specifically, after pixel to be compared receives request instruction, each pixel to be compared independently with its phase Adjacent real pixel carries out the comparison of signal amplitude, and chooses a signal amplitude in the comparison domain of each pixel to be compared Maximum real pixel is used as corresponding region center pixel.
When real pixel at the bottom-right location of virtual pixel and virtual pixel has corresponding relationship, by virtual pixel Real pixel at bottom-right location eight real pixels adjacent with its are as pixel to be compared, by each pixel to be compared point It is not independent on its own, upper left, a left side, lower left position four real pixels carry out signal amplitude compared with, and at each Comparison domain one signal amplitude maximum real pixel of selection of pixel to be compared is used as corresponding region center pixel.
When real pixel at the upper-right position of virtual pixel and virtual pixel has corresponding relationship, by virtual pixel Real pixel at upper-right position eight real pixels adjacent with its are as pixel to be compared, by each pixel to be compared point It is not independent under its own, lower-left, a left side, top-left position four real pixels carry out signal amplitude compared with, and at each Comparison domain one signal amplitude maximum real pixel of selection of pixel to be compared is used as corresponding region center pixel.
When the real pixel of virtual pixel and the lower left position of virtual pixel has corresponding relationship, by virtual pixel The real pixel of lower left position eight real pixels adjacent with its are as pixel to be compared, by each pixel to be compared point It is not independent on its own, upper right, the right side, bottom-right location four real pixels carry out signal amplitude compared with, and at each Comparison domain one signal amplitude maximum real pixel of selection of pixel to be compared is used as corresponding region center pixel.
When real pixel at the top-left position of virtual pixel and virtual pixel has corresponding relationship, by virtual pixel Real pixel at top-left position eight real pixels adjacent with its are as pixel to be compared, by each pixel to be compared point It is not independent under its own, bottom right, the right side, upper-right position four real pixels carry out signal amplitude compared with, and at each Comparison domain one signal amplitude maximum real pixel of selection of pixel to be compared is used as corresponding region center pixel.
Multiple regions center pixel is compared by step S308, is obtained the maximum real pixel of wherein signal amplitude and is made For center pixel, using the position of center pixel as photon in-position.
Specifically, adjacent thereto four real pixel of each pixel to be compared independently is compared, will be every The maximum real pixel of signal amplitude is as corresponding region center pixel in the comparison domain of one pixel to be compared.By multiple phases Answer regional center pixel to be compared again, using the maximum real pixel of signal amplitude in multiple corresponding region center pixels as Center pixel, the wherein position where center pixel, that is, photon in-position.
More specifically, the real pixel with virtual pixel with corresponding relationship and with the real pixel with corresponding relationship it is Adjacent eight real pixel at center is as pixel to be compared, each pixel to be compared independently adjacent thereto true Pixel is compared, and nine corresponding region center pixels is obtained, then nine corresponding region center pixels are compared, by nine Position, that is, photon of pixel centered on the maximum real pixel of signal amplitude in corresponding region center pixel, center pixel reaches Position.
Above-mentioned detector photon reaches information and determines in method, can will acquire for the processor of real pixel true The signal of pixel is transmitted to the processor of Medical Devices, has the processor of the real pixel of corresponding relationship by structure with virtual pixel The Signal averaging for building the real pixel of virtual pixel obtains virtual pixel signal, and virtual pixel signal is transmitted to medical treatment and is set Standby processor.The processor of Medical Devices judges whether virtual pixel signal is more than given threshold, when virtual pixel signal is super When crossing given threshold, using signal amplitude be more than given threshold time as photon arrival time, and the processing of Medical Devices Device sends request instruction, the place of the corresponding real pixel of pixel to be compared to the processor of the corresponding real pixel of pixel to be compared After reason device is connected to request instruction, the real pixel adjacent with its own of each pixel to be compared independently is compared It is compared to obtain signal to the maximum corresponding region center pixel of multiple signal amplitudes, then by multiple corresponding region center pixels The center pixel of amplitude maximum, using the position of center pixel as photon in-position.
Or the signal of real pixel that will acquire of the processor of real pixel is transmitted to the processing of Medical Devices Device, the processor of Medical Devices will construct the Signal averaging of the real pixel of virtual pixel, obtain virtual pixel signal, judge void Whether quasi- picture element signal is more than given threshold, is more than setting threshold by signal amplitude when virtual pixel signal is more than given threshold The time of value as photon arrival time, and the processor of Medical Devices by each pixel to be compared independently and its Itself adjacent real pixel is compared to obtain the maximum corresponding region center pixel of multiple signal amplitudes, then will be multiple corresponding Regional center pixel is compared to obtain the maximum center pixel of signal amplitude, reaches position for the position of center pixel as photon It sets.That is detector photon reaches information and determines that method can be run in the processor of a Medical Devices completely, It can cooperate and complete by the processor of real pixel and the processor of Medical Devices.Processor of the present embodiment to operation It is not specifically limited, only needs that above-mentioned calculation method can be completed.
Above-mentioned detector photon reaches information and determines method, and threshold time can be crossed according to virtual pixel and accurately determines photon Arrival time.And by comparing signal amplitude, pixel centered on the real pixel of the number of winning the confidence amplitude maximum, with center pixel Position can accurately determine the position that photon reaches as photon in-position, eliminate the dry of the electron cloud of photon generation It disturbs, determines photon in-position more accurate, further can be improved image quality.
As shown in figure 4, provide the schematic diagram of a kind of virtual pixel and real pixel, wherein each Pixel (pixel) Represent a real pixel.A virtual pixel is configured between Pixel1, Pixel2, Pixel3 and Pixel4 in figure. The signal of virtual pixel is the superposition of the signal of the signal of Pixel1, the signal of Pixel2, the signal of Pixel3 and Pixel4. If final calculation result is that Pixel4 is center pixel, the position of this real pixel of Pixel4 is the arrival of photon Position.
As shown in figure 5, the electron cloud for providing photon generation works as light by a received location determining method of real pixel The electron cloud 100% that son generates is received by No. 13 real pixels, and signal amplitude is more than the virtual pixel packet of given threshold at this time It includes:7,8,12, No. 13 real pixels building virtual pixel, 8,9,13, No. 14 real pixels building virtual pixel, 12,13, 17, the virtual pixel of No. 18 real pixels building, the virtual pixel of 13,14,18, No. 19 real pixels building.With virtual pixel Illustrate for there is corresponding relationship with the real pixel at the bottom-right location of virtual pixel.Then No. 13 real pixels are corresponding virtual Pixel, the corresponding virtual pixel of No. 14 real pixels, the corresponding virtual pixel of No. 18 real pixels, No. 19 real pixels are corresponding Virtual pixel signal amplitude is more than given threshold.It is arrived what the pixel to be compared of virtual pixel real pixel adjacent thereto compared Regional center pixel, then regional center pixel is compared to obtain No. 13 real pixels to be center pixel, it is final to determine No. 13 Real pixel position is photon in-position, and the signal amplitude of virtual pixel is more than to reach for photon the time of given threshold Time.
As shown in fig. 6, the electron cloud for providing photon generation works as light by the received location determining method of multiple real pixels The electron cloud 50% that son generates is received by No. 13 real pixels, 20% is received by No. 14 real pixels, 10% true by No. 18 Real image element receives, 20% is received by No. 19 real pixels.The virtual pixel for receiving photon at this time includes:7,8,12,13 The virtual pixel of number real pixel building receives the 50% of photon-electron cloud, the virtual representation of 8,9,13, No. 14 real pixels building Element receives the 70% of photon-electron cloud, and the virtual pixel of 9,10,14, No. 15 real pixel buildings receives photon-electron cloud 20%, the virtual pixel of 12,13,17, No. 18 real pixel buildings receives the 60% of photon-electron cloud, and 13,14,18, No. 19 true The virtual pixel of real image element building receives the 100% of photon-electron cloud, the virtual pixel of 14,15,19, No. 20 real pixels building The 40% of photon-electron cloud is received, the virtual pixel of 17,18,22, No. 23 real pixel buildings receives the 10% of photon-electron cloud, 18, the virtual pixel of 19,23, No. 24 real pixel buildings receives the 30% of photon-electron cloud, 19,20,24, No. 25 real pixels The virtual pixel of building receives the 20% of photon-electron cloud.Wherein signal amplitude is more than that the virtual pixel of given threshold includes:8, 9, the virtual pixel of 13, No. 14 real pixel buildings receives the 70% of photon-electron cloud, 12,13,17, No. 18 real pixel buildings Virtual pixel receive the 60% of photon-electron cloud, the virtual pixel of 13,14,18, No. 19 real pixels building receives photon electricity The 100% of sub- cloud.Illustrate so that the real pixel at the bottom-right location of virtual pixel and virtual pixel has corresponding relationship as an example.Then The corresponding virtual pixel of No. 14 real pixels, the corresponding virtual pixel of No. 18 real pixels, No. 19 real pixels are corresponding virtual Picture element signal amplitude is more than given threshold.By the pixel to be compared of virtual pixel real pixel adjacent thereto compare to region Center pixel, then regional center pixel is compared to obtain No. 13 real pixels to be center pixel, final determining No. 13 are true Pixel position is photon in-position, and the signal amplitude of virtual pixel is more than when reaching for photon the time of given threshold Between.
It should be understood that although each step in the flow chart of Fig. 1-3 is successively shown according to the instruction of arrow, These steps are not that the inevitable sequence according to arrow instruction successively executes.Unless expressly stating otherwise herein, these steps Execution there is no stringent sequences to limit, these steps can execute in other order.Moreover, at least one in Fig. 1-3 Part steps may include that perhaps these sub-steps of multiple stages or stage are not necessarily in synchronization to multiple sub-steps Completion is executed, but can be executed at different times, the execution sequence in these sub-steps or stage is also not necessarily successively It carries out, but can be at least part of the sub-step or stage of other steps or other steps in turn or alternately It executes.
In one embodiment, as shown in fig. 7, providing a kind of detector photon arrival information determining means 100, packet It includes:Virtual pixel constructs module 110, photon in-position determining module 120 and photon arrival time determining module 130, In:
Virtual pixel constructs module 110, for constructing a void between the adjacent real pixel in any preset quantity Quasi- pixel.
Photon in-position determining module 120, for presetting when the signal amplitude of virtual pixel is more than given threshold In the adjacent real pixel and real pixel adjacent thereto of quantity centered on the acquisition maximum real pixel of signal amplitude Pixel, using the position of center pixel as photon in-position.
Photon arrival time determining module 130, for the threshold time of crossing of virtual pixel to be labeled as photon arrival time.
As shown in figure 8, providing the structural block diagram of photon in-position determining module 120, wherein photon in-position is true Cover half block 120 includes:Corresponding relationship determination unit 121, pixel value determining unit to be compared 122, comparing unit 123 and photon arrive Up to position determination unit 124.
Corresponding relationship determination unit 121, one in adjacent real pixel for determining virtual pixel and preset quantity It is a that there is corresponding relationship.
Pixel value determining unit 122 to be compared, for when the signal amplitude of virtual pixel be more than given threshold when, will with it is virtual Real pixel of the pixel with corresponding relationship and adjacent multiple real pixels centered on the real pixel with corresponding relationship As pixel to be compared, request instruction is sent to pixel to be compared.
Comparing unit 123, for respectively being compared pixel to be compared real pixel adjacent thereto according to request instruction Compared with obtaining the maximum real pixel of wherein signal amplitude as corresponding region center pixel.
Photon in-position determination unit 124 obtains wherein signal width for multiple regions center pixel to be compared It is worth pixel centered on maximum real pixel, using the position of center pixel as photon in-position.
Pixel value determining unit 122 to be compared is also used to by the real pixel with virtual pixel with corresponding relationship and with tool There are adjacent eight real pixels centered on the real pixel of corresponding relationship as pixel to be compared.
Comparing unit 123, be also used to according to request instruction by pixel to be compared it is independent with its own on, upper left, Zuo He Four pixels of lower-left are compared.
The specific restriction for reaching information determining means 100 about detector photon may refer to above for detector light Son reaches the restriction that information determines method, and details are not described herein.Above-mentioned detector photon reaches each in information determining means 100 A module can be realized fully or partially through software, hardware and combinations thereof.Above-mentioned each module can be embedded in the form of hardware or Independently of in the processor in Medical Devices, can also be stored in a software form in the memory in Medical Devices, in order to Processor, which calls, executes the corresponding operation of the above modules.
In one embodiment, a kind of Medical Devices are provided, which can be ray detector, inside Structure chart can be as shown in Figure 9.The Medical Devices include the processor connected by system bus, memory, network interface, show Display screen and input unit.Wherein, the processor of the Medical Devices is for providing calculating and control ability.The storage of the Medical Devices Device includes non-volatile memory medium, built-in storage.The non-volatile memory medium is stored with operating system and computer program. The built-in storage provides environment for the operation of operating system and computer program in non-volatile memory medium.The Medical Devices Network interface be used to communicate with external terminal by network connection.To realize one when the computer program is executed by processor Kind detector photon reaches information and determines method.The display screen of the Medical Devices can be liquid crystal display or electric ink is aobvious Display screen, the input unit of the Medical Devices can be the touch layer covered on display screen, be also possible to set on Medical Devices shell Key, trace ball or the Trackpad set can also be external keyboard, Trackpad or mouse etc..
It will be understood by those skilled in the art that structure shown in Fig. 9, only part relevant to application scheme is tied The block diagram of structure, does not constitute the restriction for the Medical Devices being applied thereon to application scheme, and specific Medical Devices can be with Including than more or fewer components as shown in the figure, perhaps combining certain components or with different component layouts.
In one embodiment, a kind of Medical Devices, including memory and processor are provided, is stored with meter in memory Calculation machine program, the processor realize following steps when executing computer program:
A virtual pixel is constructed between the adjacent real pixel of any preset quantity;When the signal width of virtual pixel When value is more than given threshold, signal amplitude is obtained in the adjacent real pixel and real pixel adjacent thereto of preset quantity Pixel centered on maximum real pixel, using the position of center pixel as photon in-position.
In one embodiment, following steps are also realized when processor executes computer program:
A virtual pixel is constructed between the adjacent real pixel of any preset quantity;When the signal width of virtual pixel When value is more than given threshold, the threshold time of crossing of virtual pixel is labeled as photon arrival time;In the adjacent true of preset quantity Pixel centered on the acquisition maximum real pixel of signal amplitude in real image element and real pixel adjacent thereto, by center pixel Position as photon in-position.
In one embodiment, following steps are also realized when processor executes computer program:
A virtual pixel is constructed between the adjacent real pixel of any preset quantity;Virtual pixel and preset quantity Adjacent real pixel in one have corresponding relationship;It, will be empty when the signal amplitude of virtual pixel is more than given threshold The threshold time of crossing of quasi- pixel is labeled as photon arrival time, and by the real pixel with virtual pixel with corresponding relationship and with tool There are adjacent multiple real pixels centered on the real pixel of corresponding relationship as pixel to be compared, is asked to pixel to be compared transmission Ask instruction;Pixel to be compared real pixel adjacent thereto is compared respectively according to request instruction, obtains wherein signal width It is worth maximum real pixel as corresponding region center pixel;Multiple regions center pixel is compared, wherein signal is obtained Pixel centered on the real pixel of amplitude maximum, using the position of center pixel as photon in-position.
In one embodiment, a kind of computer readable storage medium is provided, computer program is stored thereon with, is calculated Machine program realizes following steps when being executed by processor:
A virtual pixel is constructed between the adjacent real pixel of any preset quantity;When the signal width of virtual pixel When value is more than given threshold, signal amplitude is obtained in the adjacent real pixel and real pixel adjacent thereto of preset quantity Pixel centered on maximum real pixel, using the position of center pixel as photon in-position.
In one embodiment, following steps are also realized when computer program is executed by processor:
A virtual pixel is constructed between the adjacent real pixel of any preset quantity;When the signal width of virtual pixel When value is more than given threshold, the threshold time of crossing of virtual pixel is labeled as photon arrival time;In the adjacent true of preset quantity Pixel centered on the acquisition maximum real pixel of signal amplitude in real image element and real pixel adjacent thereto, by center pixel Position as photon in-position.
In one embodiment, following steps are also realized when computer program is executed by processor:
A virtual pixel is constructed between the adjacent real pixel of any preset quantity;Virtual pixel and preset quantity Adjacent real pixel in one have corresponding relationship;It, will be empty when the signal amplitude of virtual pixel is more than given threshold The threshold time of crossing of quasi- pixel is labeled as photon arrival time, and by the real pixel with virtual pixel with corresponding relationship and with tool There are adjacent multiple real pixels centered on the real pixel of corresponding relationship as pixel to be compared, is asked to pixel to be compared transmission Ask instruction;Pixel to be compared real pixel adjacent thereto is compared respectively according to request instruction, obtains wherein signal width It is worth maximum real pixel as corresponding region center pixel;Multiple regions center pixel is compared, wherein signal is obtained Pixel centered on the real pixel of amplitude maximum, using the position of center pixel as photon in-position.
Those of ordinary skill in the art will appreciate that realizing all or part of the process in above-described embodiment method, being can be with Instruct relevant hardware to complete by computer program, computer program to can be stored in a non-volatile computer readable It takes in storage medium, the computer program is when being executed, it may include such as the process of the embodiment of above-mentioned each method.Wherein, this Shen Please provided by any reference used in each embodiment to memory, storage, database or other media, may each comprise Non-volatile and/or volatile memory.Nonvolatile memory may include read-only memory (ROM), programming ROM (PROM), electrically programmable ROM (EPROM), electrically erasable ROM (EEPROM) or flash memory.Volatile memory may include Random access memory (RAM) or external cache.By way of illustration and not limitation, RAM is available in many forms, Such as static state RAM (SRAM), dynamic ram (DRAM), synchronous dram (SDRAM), double data rate sdram (DDRSDRAM), enhancing Type SDRAM (ESDRAM), synchronization link (Synchlink) DRAM (SLDRAM), memory bus (Rambus) direct RAM (RDRAM), direct memory bus dynamic ram (DRDRAM) and memory bus dynamic ram (RDRAM) etc..
Each technical characteristic of above embodiments can be combined arbitrarily, for simplicity of description, not to above-described embodiment In each technical characteristic it is all possible combination be all described, as long as however, the combination of these technical characteristics be not present lance Shield all should be considered as described in this specification.
The several embodiments of the application above described embodiment only expresses, the description thereof is more specific and detailed, but simultaneously It cannot therefore be construed as limiting the scope of the patent.It should be pointed out that coming for those of ordinary skill in the art It says, without departing from the concept of this application, various modifications and improvements can be made, these belong to the protection of the application Range.Therefore, the scope of protection shall be subject to the appended claims for the application patent.

Claims (10)

1. a kind of detector photon reaches information and determines method, which is characterized in that the method includes:
A virtual pixel is constructed between the adjacent real pixel of any preset quantity;
When the signal amplitude of the virtual pixel be more than given threshold when, the preset quantity adjacent real pixel and with Pixel centered on the acquisition maximum real pixel of signal amplitude in its adjacent real pixel, by the position of the center pixel As photon in-position.
2. the method according to claim 1, wherein true adjacent with the preset quantity of the virtual pixel One in real image element has corresponding relationship;
It is described when the signal amplitude of the virtual pixel be more than given threshold when, in the adjacent real pixel of the preset quantity With in real pixel adjacent thereto obtain the maximum real pixel of signal amplitude centered on pixel, by the center pixel Position as photon in-position, including:
When the signal amplitude of the virtual pixel is more than given threshold, will there is the true of corresponding relationship with the virtual pixel Pixel and adjacent multiple real pixels using centered on the real pixel with corresponding relationship are as pixel to be compared, to institute It states pixel to be compared and sends request instruction;
The pixel to be compared real pixel adjacent thereto is compared respectively according to the request instruction, wherein being believed The real pixel of number amplitude maximum is as corresponding region center pixel;
Multiple regional center pixels are compared, picture centered on the maximum real pixel of wherein signal amplitude is obtained Element, using the position of the center pixel as photon in-position.
3. according to the method described in claim 2, it is characterized in that, the preset quantity is four;The virtual pixel and institute Stating the real pixel at the bottom-right location of virtual pixel has corresponding relationship.
4. according to the method described in claim 3, it is characterized in that, the signal of the virtual pixel is the phase of the preset quantity The Signal averaging of adjacent real pixel.
5. according to the method described in claim 4, it is characterized in that, described will have the true of corresponding relationship with the virtual pixel Real image element and adjacent multiple real pixels using centered on the real pixel with corresponding relationship are wrapped as pixel to be compared It includes:
In being with real pixel of the virtual pixel with corresponding relationship and with the real pixel with corresponding relationship Adjacent eight real pixels of the heart are as pixel to be compared.
6. according to method described in claim 3 to 5 any one, which is characterized in that described to be distinguished according to the request instruction The pixel to be compared real pixel adjacent thereto is compared, including:
According to the request instruction by independent four with its own upper, upper left, a left side and lower-left of the pixel to be compared really Pixel is compared.
7. the method according to claim 1, wherein the method also includes:
The threshold time of crossing of the virtual pixel is labeled as photon arrival time.
8. a kind of detector photon reaches information determining means, which is characterized in that described device includes:
Virtual pixel constructs module, for constructing a virtual pixel between the adjacent real pixel in any preset quantity;
Photon in-position determining module, for when the signal amplitude of the virtual pixel be more than given threshold when, described pre- If being obtained in the adjacent real pixel and real pixel adjacent thereto of quantity in the maximum real pixel conduct of signal amplitude Imago element, using the position of the center pixel as photon in-position.
9. a kind of Medical Devices, including memory and processor, the memory are stored with computer program, which is characterized in that The step of processor realizes any one of claims 1 to 7 the method when executing the computer program.
10. a kind of computer readable storage medium, is stored thereon with computer program, which is characterized in that the computer program The step of method described in any one of claims 1 to 7 is realized when being executed by processor.
CN201810553188.0A 2018-05-31 2018-05-31 Detector photon arrival information determination method and device and medical equipment Active CN108926356B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201810553188.0A CN108926356B (en) 2018-05-31 2018-05-31 Detector photon arrival information determination method and device and medical equipment

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201810553188.0A CN108926356B (en) 2018-05-31 2018-05-31 Detector photon arrival information determination method and device and medical equipment

Publications (2)

Publication Number Publication Date
CN108926356A true CN108926356A (en) 2018-12-04
CN108926356B CN108926356B (en) 2022-03-25

Family

ID=64449303

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201810553188.0A Active CN108926356B (en) 2018-05-31 2018-05-31 Detector photon arrival information determination method and device and medical equipment

Country Status (1)

Country Link
CN (1) CN108926356B (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110226943A (en) * 2019-07-05 2019-09-13 上海联影医疗科技有限公司 Calculation method of parameters, device and the computer equipment of photon arrival detector
CN111494813A (en) * 2020-04-21 2020-08-07 上海联影医疗科技有限公司 Modeling method, verification method, device, equipment and storage medium

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20080251730A1 (en) * 2005-10-05 2008-10-16 Organisation Europeenne Pour La Rechierche Nucleaire Method for Determining a Particle and Sensor Device Therefor
CN101680953A (en) * 2007-05-16 2010-03-24 皇家飞利浦电子股份有限公司 Virtual pet detector and quasi-pixelated readout scheme for pet
CN104570042A (en) * 2014-12-11 2015-04-29 沈阳东软医疗系统有限公司 Nuclear detector crystal position recognizing method and device
US20150260854A1 (en) * 2012-10-08 2015-09-17 Commissariat A L'energie Atomique Et Aux Energies Alternatives Method and device for detecting ionising radiation using a pixelated photodetector
CN105917637A (en) * 2013-10-29 2016-08-31 原子能和辅助替代能源委员会 Method for processing signals collected by pixels of a detector
CN106656118A (en) * 2016-09-28 2017-05-10 沈阳东软医疗系统有限公司 Circuit for obtaining time for photons to reach detector and detector
CN106680860A (en) * 2015-11-11 2017-05-17 Fei公司 Method for detecting particulate radiation

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20080251730A1 (en) * 2005-10-05 2008-10-16 Organisation Europeenne Pour La Rechierche Nucleaire Method for Determining a Particle and Sensor Device Therefor
CN101680953A (en) * 2007-05-16 2010-03-24 皇家飞利浦电子股份有限公司 Virtual pet detector and quasi-pixelated readout scheme for pet
US20150260854A1 (en) * 2012-10-08 2015-09-17 Commissariat A L'energie Atomique Et Aux Energies Alternatives Method and device for detecting ionising radiation using a pixelated photodetector
CN105917637A (en) * 2013-10-29 2016-08-31 原子能和辅助替代能源委员会 Method for processing signals collected by pixels of a detector
CN104570042A (en) * 2014-12-11 2015-04-29 沈阳东软医疗系统有限公司 Nuclear detector crystal position recognizing method and device
CN106680860A (en) * 2015-11-11 2017-05-17 Fei公司 Method for detecting particulate radiation
CN106656118A (en) * 2016-09-28 2017-05-10 沈阳东软医疗系统有限公司 Circuit for obtaining time for photons to reach detector and detector

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110226943A (en) * 2019-07-05 2019-09-13 上海联影医疗科技有限公司 Calculation method of parameters, device and the computer equipment of photon arrival detector
CN110226943B (en) * 2019-07-05 2023-08-15 上海联影医疗科技股份有限公司 Parameter calculation method and device for photon arrival detector and computer equipment
CN111494813A (en) * 2020-04-21 2020-08-07 上海联影医疗科技有限公司 Modeling method, verification method, device, equipment and storage medium

Also Published As

Publication number Publication date
CN108926356B (en) 2022-03-25

Similar Documents

Publication Publication Date Title
CN105852889B (en) Control device and control method
US10073438B2 (en) Assessing machine trajectories for collision avoidance
CN108926356A (en) Detector photon reaches information and determines method, apparatus and Medical Devices
CN109754447A (en) Image generating method, device, equipment and storage medium
JP2014113444A (en) Image processing apparatus, image processing method, and program
CN110325843A (en) Guiding integrated circuit defects detection
CN110390679A (en) Image processing method, computer equipment and readable storage medium storing program for executing
CN108542414B (en) The scatter correction method and device of computed tomography image
CN109567852A (en) The determination method of scanning range, the acquisition methods of medical image, device and equipment
CN110291384A (en) The method and system of failure prediction for integrated circuit
EP3806129A1 (en) Systems and methods for focal point position correction
US10888293B2 (en) Radiographic image capturing system and method for generating and displaying combined image for check
CN112084557A (en) Method, device and equipment for quickly calculating house type design area and storage medium
CN110063738A (en) Image processing apparatus, radiation imaging system, radiation wire length image capturing method and recording medium
CN107548083A (en) WAP function test method and equipment
CN109284857A (en) Power distribution room planing method and relevant device based on power distribution room horizontal layout
CN105913397B (en) A kind of modification method of reconstruction image, device and equipment
EP4331491A1 (en) Region-of-interest extraction method and apparatus, and device, system and storage medium
JP2017012444A (en) Image processing device, image processing method and image processing program
CN107753054B (en) Image correction method, image correction device, CT system and storage medium
CN111159027B (en) Automatic testing method and device, computer equipment and readable storage medium
CN109727234B (en) Display panel generation method, scanning range planning method and equipment
JP2019017760A (en) Radiation image capturing device, and radiation image capturing system
CN114090351A (en) Signal testing method and device, computer equipment and storage medium
CN106923851A (en) The calibrating installation and method of X-ray detecting equipment and X-ray detector

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
CB02 Change of applicant information

Address after: 201807 Shanghai City, north of the city of Jiading District Road No. 2258

Applicant after: Shanghai Lianying Medical Technology Co., Ltd

Address before: 201807 Shanghai City, north of the city of Jiading District Road No. 2258

Applicant before: SHANGHAI UNITED IMAGING HEALTHCARE Co.,Ltd.

CB02 Change of applicant information
GR01 Patent grant
GR01 Patent grant