CN108904663A - It is a kind of to treat dermopathic drug and preparation method thereof - Google Patents

It is a kind of to treat dermopathic drug and preparation method thereof Download PDF

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Publication number
CN108904663A
CN108904663A CN201811191513.XA CN201811191513A CN108904663A CN 108904663 A CN108904663 A CN 108904663A CN 201811191513 A CN201811191513 A CN 201811191513A CN 108904663 A CN108904663 A CN 108904663A
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parts
drug
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radix
dragon
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王北斗
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
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    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232—Angelica
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/286—Carthamus (distaff thistle)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484—Glycyrrhiza (licorice)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/60—Moraceae (Mulberry family), e.g. breadfruit or fig
    • A61K36/605—Morus (mulberry)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/889—Arecaceae, Palmae or Palmaceae (Palm family), e.g. date or coconut palm or palmetto
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/10—Anti-acne agents
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/16—Otologicals
    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A61K2236/35—Extraction with lipophilic solvents, e.g. Hexane or petrol ether

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Abstract

Dermopathic drug and preparation method thereof is treated the invention discloses a kind of, by weight, including following raw material：45-55 parts windproof, 45-55 parts of the root of Dahurain angelica, 55-65 parts of leaf of Chinese ilex, 90-110 parts of Radix Notoginseng, 14-18 parts of safflower, 90-110 parts of dragon's blood, 35-45 parts of frosted mulberry leaf, 8-12 parts of Radix Glycyrrhizae.Preparation method is that radix saposhnikoviae, the root of Dahurain angelica, leaf of Chinese ilex, safflower, frosted mulberry leaf, Radix Glycyrrhizae are impregnated 23-25h with vegetable oil, and heating is fried sallow to drug with high heat, is down to 38-42 DEG C to temperature, filtering cools completely；It is heated up to 58-62 DEG C again, Radix Notoginseng is added, while hot pours into medical fluid in container；It is finally putting into dragon's blood, after drug cools completely, dispenses to obtain the final product.The effect of playing swelling and pain relieving, saprophytic machine of dispelling, moisturizing toxin expelling by the synergistic effect of each drug, drug therapy skin disease of the invention is rapid-action, good effect, has no toxic side effect, and medication is convenient and efficient, hormone-free, preservative etc..Clinical 1260 uses, total effective rate 97.6%.

Description

It is a kind of to treat dermopathic drug and preparation method thereof
Technical field
The invention belongs to the field of Chinese medicines, and in particular to and it is a kind of to treat dermopathic drug, also relate to the treatment skin The preparation method of the drug of disease.
Background technique
Skin disease（dermatosis）It is the general name occurred in skin and skin accessory organ's disease.Skin is human body maximum Organ, dermopathic type is not only various, and the disease that a variety of internal organ occur can also have performance on the skin.Cause skin disease The reason of very much, such as skin disease caused by infective agent, such as leprosy, scabies, nosomycosis, bacterial skin infections usually have one Fixed infectiousness not only influences health, and raises fear and social discrimination, but with the improvement of people ' s living standards And scientific and technological progress, the infectious diseases such as leprosy have been obviously controlled in the whole world.
For skin as first of physiology defence line of human body and maximum organ, the moment participates in the functional activity of body, dimension The unity of opposites of body and natural environment is hold, the abnormal conditions of body can also be reflected in skin surface.Skin has The Physiological protection function of almost Perfect：Such as barrier action, sensation, adjust body temperature, absorption, secretion and Excretion Deng, maintenance body health on, play the role of highly important.The physiological function of skin is damaged, and causes skin disease.Often See that skin disease has psoriasis, bleb, brandy nose, impetigo, pyogenic baeceria infection, scar, tinea, ichthyosis, underarm odor, whelk, hair Capsulitis, pelada and lipsotrichia, andrological inflammation, infant diaper rash, corn, freckle, pompholyx, acarid dermatitis, leucoderma, eczema, ash Nail, chorionitis, pruitus, the nursing of oral cavity portion, depilation, chloasma etc..
Doctor trained in Western medicine is mostly controlled with the drugs such as antibiotic and steroids such as antihistaminicum class, corticoid and immunosupress class at present Treat skin disease.But antibiotic treatment can often bring some adverse reactions to patient, side effect is big, especially to chronic skin Disease is unable to long-term follow treatment, influences therapeutic effect, is easy recurrence and cannot eradicate.Really there are many Chinese medicines currently on the market Treatment method, wherein used in drug it is also many kinds of, but effect is irregular, I is unequal to ideal, most of Chinese medicine at Part is more, is not suitable for being used for a long time.
Summary of the invention
The purpose of the present invention is to provide a kind of rapid-action, good effects, the dermopathic drug for the treatment of having no toxic side effect.
Another object of the present invention is to provide the preparation methods of the dermopathic drug of the treatment.
It is of the invention it is a kind of treat dermopathic drug, by weight, including following raw material：
45-55 parts windproof, 45-55 parts of the root of Dahurain angelica, 55-65 parts of leaf of Chinese ilex, 90-110 parts of Radix Notoginseng, 14-18 parts of safflower, dragon's blood 90-110 Part, 35-45 parts of frosted mulberry leaf, 8-12 parts of Radix Glycyrrhizae.
It is above-mentioned it is a kind of treat dermopathic drug, by weight, preferably following raw material：
Windproof 50 parts, 50 parts of the root of Dahurain angelica, 60 parts of leaf of Chinese ilex, 100 parts of Radix Notoginseng, 16 parts of safflower, 100 parts of dragon's blood, 40 parts of frosted mulberry leaf, Radix Glycyrrhizae 10 parts.
A kind of preparation method for treating dermopathic drug of the invention, includes the following steps：
（1）Each bulk pharmaceutical chemicals are taken by weight；
（2）By radix saposhnikoviae, the root of Dahurain angelica, leaf of Chinese ilex, safflower, frosted mulberry leaf, Radix Glycyrrhizae, with 450-550 parts of immersion 23-25h of vegetable oil, with high heat Heating is fried sallow to drug, is down to 38-42 DEG C to temperature, filtering cools completely；
（3）It is heated up to 58-62 DEG C again, Radix Notoginseng is added, while hot pours into medical fluid in container；
（4）It is finally putting into dragon's blood, after drug cools completely, dispenses to obtain the final product.
Compared with prior art, the present invention there is obvious beneficial effect, as can be known from the above technical solutions：The present invention selects anti- Wind, the root of Dahurain angelica, leaf of Chinese ilex Dian Radix Notoginseng, safflower, dragon's blood, frosted mulberry leaf, Radix Glycyrrhizae are raw material, play detumescence by the synergistic effect of each drug Relieve pain, saprophytic machine of dispelling, moisturizing toxin expelling the effect of, can effectively treat long sore be not cured, scald, cracked nipple, intractable oral cavity ulcer The skin diseases such as eczema, hemorrhoid, anal fissure, tympanitis, harelip, chapped skin, fungal infection, whelk scar.Wherein chemistry is contaminated Skin allergy doctor trained in Western medicine caused by hair agent is needed using hormone, has side effect to body, has price low using drug of the invention Honest and clean, without side-effects, rapid-action feature blindly uses the mistaken ideas of antibiotic and hormone as long as overcoming inflammation allergy.For Infant eczema, the hormone etc. that doctor trained in Western medicine only will use is palliative, and the present invention has the characteristics that moisturizing anti-inflammatory, antipruritic, is free of Hormone, preservative etc..Its rapid-action, good effect, has no toxic side effect, and medication is convenient and efficient.Clinical 1260 uses, it is total effective Rate 97.6%.
Specific embodiment
The beneficial effect of the present invention will be further illustrated by the following test examples the drug.
Test example：The clinical observation of drug of the present invention
1, clinical data：
All cases 1260, wherein male 600, infant 300, female 360, max age 70 years old, minimal ages 2 years old.
2, diagnostic criteria：
《Disease of tcm Standardization of diagnosis and curative effect》.
3, treatment method：
Drug prepared by the present invention is taken, once in the morning and once at night, with suitable normal saline flushing wound, after dry, by drug It drips on skin, with hand by medical fluid uniform soft wiping repeatedly, promotes the absorption of drug.7 days as one therapeutic course.
4, criterion of therapeutical effect：
It is effective：Symptom disappears；
Effectively：Symptom is relieved；
In vain：Symptom is not improved.
5, treatment results：
1260 patients use drug of the present invention, and effective 1070, effective 160, invalid 30, obvious effective rate 84.9% is total effective Rate 97.6%.
The preparation method of this drug is illustrated by following embodiment.
Embodiment 1
A kind of preparation method for treating dermopathic drug, includes the following steps：
（1）Weigh bulk pharmaceutical chemicals radix saposhnikoviae 45g, root of Dahurain angelica 55g, leaf of Chinese ilex 55g, Radix Notoginseng 110g, safflower 14g, dragon's blood 110g, frosted mulberry leaf 35g, Radix Glycyrrhizae 12g；
（2）By radix saposhnikoviae, the root of Dahurain angelica, leaf of Chinese ilex, safflower, frosted mulberry leaf, Radix Glycyrrhizae, 25h is impregnated with vegetable oil 450ml, heating is fried with high heat It is sallow to drug, 38 DEG C are down to temperature, is cooled completely；
（3）It is heated up to 62 DEG C again, Radix Notoginseng is added, while hot pours into medical fluid in container；
（4）It is finally putting into dragon's blood, after drug cools completely, dispenses to obtain the final product.
Embodiment 2
A kind of preparation method for treating dermopathic drug, includes the following steps：
（1）Weigh bulk pharmaceutical chemicals radix saposhnikoviae 50g, root of Dahurain angelica 50g, leaf of Chinese ilex 60g, Radix Notoginseng 100g, safflower 16g, dragon's blood 100g, frosted mulberry leaf 40g, Radix Glycyrrhizae 10g；
（2）By radix saposhnikoviae, the root of Dahurain angelica, leaf of Chinese ilex, safflower, frosted mulberry leaf, Radix Glycyrrhizae, impregnated for 24 hours with pure rape oil 500ml, heating is fried with high heat It is sallow to drug, 40 DEG C are down to temperature, with filtered through gauze, is cooled completely；
（3）It is heated up to 60 DEG C again, Radix Notoginseng is added, while hot pours into medical fluid in container；
（4）It is finally putting into dragon's blood, after drug cools completely, dispenses to obtain the final product.
Embodiment 3
A kind of preparation method for treating dermopathic drug, includes the following steps：
（1）Weigh bulk pharmaceutical chemicals radix saposhnikoviae 55g, root of Dahurain angelica 45g, leaf of Chinese ilex 65g, Radix Notoginseng 90g, safflower 18g, dragon's blood 90g, frosted mulberry leaf 45g, Radix Glycyrrhizae 8g；
（2）By radix saposhnikoviae, the root of Dahurain angelica, leaf of Chinese ilex, safflower, frosted mulberry leaf, Radix Glycyrrhizae, 23h is impregnated with vegetable oil 550ml, heating is fried with high heat It is sallow to drug, 42 DEG C are down to temperature, is cooled completely；
（3）It is heated up to 58 DEG C again, Radix Notoginseng is added, while hot pours into medical fluid in container；
（4）It is finally putting into dragon's blood, after drug cools completely, dispenses to obtain the final product.
The above described is only a preferred embodiment of the present invention, being not intended to limit the present invention in any form, Ren Hewei Be detached from technical solution of the present invention content, according to the technical essence of the invention it is to the above embodiments it is any it is simple modification, etc. With variation and modification, all of which are still within the scope of the technical scheme of the invention.

Claims (3)

1. a kind of treat dermopathic drug, by weight, including following raw material：
45-55 parts windproof, 45-55 parts of the root of Dahurain angelica, 55-65 parts of leaf of Chinese ilex, 90-110 parts of Radix Notoginseng, 14-18 parts of safflower, dragon's blood 90-110 Part, 35-45 parts of frosted mulberry leaf, 8-12 parts of Radix Glycyrrhizae.
2. a kind of as described in claim 1 treat dermopathic drug, by weight, preferably following raw material：
Windproof 50 parts, 50 parts of the root of Dahurain angelica, 60 parts of leaf of Chinese ilex, 100 parts of Radix Notoginseng, 16 parts of safflower, 100 parts of dragon's blood, 40 parts of frosted mulberry leaf, Radix Glycyrrhizae 10 parts.
3. a kind of as claimed in claim 1 or 2 treat dermopathic drug, preparation method includes the following steps：
（1）Each bulk pharmaceutical chemicals are taken by weight；
（2）By radix saposhnikoviae, the root of Dahurain angelica, leaf of Chinese ilex, safflower, frosted mulberry leaf, Radix Glycyrrhizae, with 450-550 parts of immersion 23-25h of vegetable oil, with high heat Heating is fried sallow to drug, is down to 38-42 DEG C to temperature, filtering cools completely；
（3）It is heated up to 58-62 DEG C again, Radix Notoginseng is added, while hot pours into medical fluid in container；
（4）It is finally putting into dragon's blood, after drug cools completely, dispenses to obtain the final product.
CN201811191513.XA 2018-10-12 2018-10-12 It is a kind of to treat dermopathic drug and preparation method thereof Pending CN108904663A (en)

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Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1814101A (en) * 2005-12-08 2006-08-09 金德成 Chinese medicine for treating ulcerative stomatitis

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1814101A (en) * 2005-12-08 2006-08-09 金德成 Chinese medicine for treating ulcerative stomatitis

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