CN108873171B - A multi-core fiber-like Bessel beam array optical tweezers - Google Patents

A multi-core fiber-like Bessel beam array optical tweezers Download PDF

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CN108873171B
CN108873171B CN201810779470.0A CN201810779470A CN108873171B CN 108873171 B CN108873171 B CN 108873171B CN 201810779470 A CN201810779470 A CN 201810779470A CN 108873171 B CN108873171 B CN 108873171B
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CN108873171A (en
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张亚勋
汤晓云
张羽
刘志海
杨军
苑立波
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Harbin Engineering University
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    • GPHYSICS
    • G02OPTICS
    • G02BOPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B6/00Light guides; Structural details of arrangements comprising light guides and other optical elements, e.g. couplings
    • G02B6/24Coupling light guides
    • G02B6/255Splicing of light guides, e.g. by fusion or bonding
    • GPHYSICS
    • G02OPTICS
    • G02BOPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B6/00Light guides; Structural details of arrangements comprising light guides and other optical elements, e.g. couplings
    • G02B6/02Optical fibres with cladding with or without a coating
    • GPHYSICS
    • G02OPTICS
    • G02BOPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B6/00Light guides; Structural details of arrangements comprising light guides and other optical elements, e.g. couplings
    • G02B6/02Optical fibres with cladding with or without a coating
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    • GPHYSICS
    • G02OPTICS
    • G02BOPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B6/00Light guides; Structural details of arrangements comprising light guides and other optical elements, e.g. couplings
    • G02B6/24Coupling light guides
    • G02B6/255Splicing of light guides, e.g. by fusion or bonding
    • G02B6/2552Splicing of light guides, e.g. by fusion or bonding reshaping or reforming of light guides for coupling using thermal heating, e.g. tapering, forming of a lens on light guide ends
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    • G21KTECHNIQUES FOR HANDLING PARTICLES OR IONISING RADIATION NOT OTHERWISE PROVIDED FOR; IRRADIATION DEVICES; GAMMA RAY OR X-RAY MICROSCOPES
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Abstract

A multi-core optical fiber Bessel beam array optical tweezers belongs to the technical field of optical trapping. The optical fiber comprises a multi-core optical fiber, a step multimode optical fiber and a laser light source, wherein a tail fiber of the laser light source is connected with one end of the multi-core optical fiber in a melting taper coupling mode, the other end of the multi-core optical fiber is in conventional coaxial fusion welding with one end of the step multimode optical fiber, and the other end of the step multimode optical fiber is prepared into an approximate semi-sphere structure with the radius R through melting processing. The invention relates to a novel all-fiber array optical tweezers based on Bessel-like light beams, which can be used for batch operation and screening of a plurality of tiny particles and realizes three-dimensional array arrangement of specific positions; the change of the quantity of the light potential well and the quantity of the captured particles can be realized by adjusting the number of the fiber cores of the multi-core fiber, the length of the step multimode fiber and the fused biconical taper shape of one end of the step multimode fiber, and the microscopic fine operation of the tiny particles is realized, so that the method has wide application value in the field of biomedical research.

Description

一种多芯光纤类贝塞尔光束阵列光镊A multi-core fiber-like Bessel beam array optical tweezers

技术领域technical field

本发明属于光学捕获技术领域,具体涉及一种多芯光纤类贝塞尔光束阵列光镊。The invention belongs to the technical field of optical capture, and in particular relates to a multi-core optical fiber type Bessel beam array optical tweezers.

背景技术Background technique

光镊是利用光强分布的梯度力和散射力俘获和操纵粒子的工具。由美国贝尔实验室的 Askin及其同事与1986年首次提出(Optics Letters,18(5):288-290,1986),一种基于单光束激光的三维光学势阱,用于实现对微小粒子的三维控制,因此光束可实现空间对微小粒子的夹持,得名“光镊”。此后,光镊技术发展迅速,成为重要的研究技术手段,使其广泛应用于各种微小粒子的操作领域中,从数百微米的粒子到纳米粒子,从活体细胞到DNA生物大分子链都可以用光镊进行捕获和操作。Optical tweezers are tools for trapping and manipulating particles using the gradient force and scattering force of light intensity distribution. It was first proposed by Askin and his colleagues at Bell Labs in the United States in 1986 (Optics Letters, 18(5): 288-290, 1986), a three-dimensional optical potential well based on a single-beam laser, which is used to realize the detection of tiny particles. Three-dimensional control, so the light beam can realize the clamping of tiny particles in space, so it is named "optical tweezers". Since then, optical tweezers technology has developed rapidly and has become an important research technique, making it widely used in the field of manipulation of various tiny particles, ranging from particles of hundreds of microns to nanoparticles, from living cells to DNA biological macromolecular chains. Capture and manipulate with optical tweezers.

由于传统光镊系统基于光学显微系统其体积较大、在结构上缺乏灵活性、操作自由度较小。光纤作为波导介质,其柔性特征更适合于在复杂空间中进行微操作。与常规光镊系统相比,光纤光镊因其具有结构简单、价格低廉、操作灵活等特点而得到发展。Because the traditional optical tweezers system is based on the optical microscope system, it is bulky, lacks flexibility in structure, and has less freedom of operation. As a waveguide medium, optical fiber is more suitable for micro-manipulation in complex space due to its flexible characteristics. Compared with conventional optical tweezers systems, fiber optic tweezers have been developed due to their simple structure, low price, and flexible operation.

由多光纤光镊发展至阵列光纤光镊技术以来,产生了多种光纤光镊系统。例如,2008年公开了名为“集成于单根光纤的多光镊”,公开号CN101251620,通过调整纤芯的几何排布结构,可实现在不同位置几何排列的多个微小粒子的同时捕获,同时使光镊的捕获性能得到极大的改善;2010年,陆续公开了公开号为CN101893736A的“基于阵列芯光纤的轴向阵列光镊及光动力控制方法”,该轴向阵列光镊在光纤末端形成的光学势阱呈正八面体结构,正八面体的顶点处形成光学势阱,通过调节压电陶瓷驱动装置的驱动电路改变阵列芯光纤方向位移进行传输光束的相位控制,实现功率分配与调整,控制该轴向阵列光镊光阱力分布;公开号为CN101907742A的“基于多芯保偏光纤的阵列式光镊及其制备方法”,该阵列式光镊可以在光纤端形成致密的干涉网格光场阵列,在相干加强点形成光学势阱对粒子实现筛选等功能。这些光镊多能实现多粒子的捕获操作等功能,但很少有可进行亚微米级粒子三维阵列捕获和操作的光镊。Since the development of multi-fiber optical tweezers to array fiber optical tweezers technology, a variety of optical fiber optical tweezers systems have been produced. For example, in 2008, a publication entitled "Multi-optical tweezers integrated in a single fiber" was published with the publication number CN101251620. By adjusting the geometrical arrangement of the fiber core, the simultaneous capture of multiple tiny particles geometrically arranged at different positions can be achieved. At the same time, the capture performance of the optical tweezers has been greatly improved; in 2010, the publication number CN101893736A "Axial Array Optical Tweezers and Optical Dynamic Control Method Based on Array Core Fiber" was published one after another. The optical potential well formed at the end has a regular octahedral structure, and the optical potential well is formed at the vertex of the regular octahedron. By adjusting the driving circuit of the piezoelectric ceramic driving device, the direction displacement of the array core fiber is changed to control the phase of the transmitted beam, and the power distribution and adjustment are realized. Control the optical trap force distribution of the axial array optical tweezers; the publication number is CN101907742A "Array optical tweezers based on multi-core polarization-maintaining fibers and preparation method thereof", the array optical tweezers can form a dense interference grid at the fiber end The optical field array forms an optical potential well at the coherent enhancement point to screen particles and other functions. Most of these optical tweezers can achieve functions such as multi-particle capture operation, but there are few optical tweezers that can capture and operate three-dimensional arrays of sub-micron particles.

发明内容SUMMARY OF THE INVENTION

针对上述现有发明,本发明提供了一种节约了物理空间的同时,实现了单光纤三维阵列捕获的基于光纤类贝塞尔光束的单光纤阵列光镊。In view of the above-mentioned prior invention, the present invention provides a single-fiber array optical tweezers based on a fiber-like Bessel beam that realizes capture by a single-fiber three-dimensional array while saving physical space.

为实现上述目的,本发明公开的一种多芯光纤类贝塞尔光束阵列光镊,包括多芯光纤(3)、阶跃多模光纤(2)和激光光源(4),激光光源(4)的尾纤(41)与多芯光纤(3)的一端熔融拉锥耦合连接,多芯光纤(3)的另一端与阶跃多模光纤(2)的一端常规同轴熔接,阶跃多模光纤(2)的另一端经熔融加工制备成半径R的近似半圆球结构(22)。In order to achieve the above purpose, a multi-core fiber-like Bessel beam array optical tweezers disclosed in the present invention comprises a multi-core fiber (3), a step multi-mode fiber (2) and a laser light source (4), the laser light source (4). ) pigtail (41) is fused and taper-coupled to one end of the multi-core fiber (3), and the other end of the multi-core fiber (3) is conventionally coaxially spliced with one end of the step multimode fiber (2). The other end of the mode optical fiber (2) is prepared into an approximate hemispherical structure (22) with a radius R by melt processing.

多芯光纤(3)的纤芯(31)的数量大于等于2,纤芯(31)的分布不固定。The number of cores (31) of the multi-core optical fiber (3) is greater than or equal to 2, and the distribution of the cores (31) is not fixed.

阶跃多模光纤(2)为芯径大于多芯光纤的纤芯距的阶跃折射率分布的多模光纤,阶跃多模光纤(2)的长度范围为200-500μm,近似半圆球结构(22)的半径R的范围为50-90μm。The step multimode optical fiber (2) is a multimode optical fiber with a step refractive index distribution whose core diameter is greater than the core distance of the multi-core optical fiber, and the length of the step multimode optical fiber (2) is in the range of 200-500 μm and has an approximate hemispherical structure. The radius R of (22) is in the range of 50-90 μm.

通过熔接电流时间的控制,控制近似半圆球结构(22)的形状。By controlling the welding current time, the shape of the approximately hemispherical structure (22) is controlled.

本发明的有益效果在于:The beneficial effects of the present invention are:

本发明为一种基于类贝塞尔光束的新型全光纤阵列光镊;利用多芯光纤与阶跃多模光纤同轴熔接在阶跃多模光纤中激发的类贝塞尔光束干涉形成致密的三维光学势阱,可用于对多个微小粒子的批量操作和筛选,实现特定位置的三维阵列排列;基于多芯光纤与阶跃多模光纤的类贝塞尔光束阵列光镊可通过对多芯光纤纤芯数目、阶跃多模光纤的长度及阶跃多模光纤一端熔融拉锥形状的调整,实现光势阱和捕获粒子数量的变更,实现微小粒子的显微精细操作,使其在生物医学研究领域有广泛的应用价值。The invention is a new type of all-fiber array optical tweezers based on Bessel-like beams; the Bessel-like beams excited in the step-multimode fibers by coaxial fusion splicing of multi-core fibers and step-multimode fibers form a dense Three-dimensional optical potential wells can be used for batch operation and screening of multiple tiny particles to achieve three-dimensional array arrangement at specific positions; Bessel-like beam array optical tweezers based on multi-core fibers and step multi-mode fibers can be used for multi-core Adjustment of the number of fiber cores, the length of the step multimode fiber and the shape of the melting taper at one end of the step multimode fiber can realize the change of the number of optical potential wells and trapped particles, and realize the microscopic and fine operation of tiny particles, so that they can be used in biology. It has a wide range of application value in the field of medical research.

附图说明Description of drawings

图1多芯光纤类贝塞尔光束阵列光镊结构及原理示意图(以五芯光纤为例);Figure 1. Schematic diagram of the structure and principle of multi-core fiber-like Bessel beam array optical tweezers (taking five-core fiber as an example);

图2(a)-(c)多芯光纤剖面图,其中图2(a)为双芯,图2(b)为四芯,图2(c)为五芯;Figures 2(a)-(c) are cross-sectional views of multi-core optical fibers, wherein Figure 2(a) is a double-core, Figure 2(b) is a four-core, and Figure 2(c) is a five-core;

图3为多芯光纤类贝塞尔光束阵列光镊的光纤探头示意图;Figure 3 is a schematic diagram of a fiber probe of a multi-core fiber Bessel beam array optical tweezers;

图4为激光光源尾纤与五芯光纤熔融拉锥耦合结构示意图。Figure 4 is a schematic diagram of the coupling structure of the laser light source pigtail and the five-core optical fiber fusion taper.

具体实施方式:Detailed ways:

下面结合附图对本发明做进一步的描述:The present invention will be further described below in conjunction with the accompanying drawings:

实施例1Example 1

一种多芯光纤类贝塞尔光束阵列光镊,包括多芯光纤(3)、阶跃多模光纤(2)和激光光源(4),激光光源(4)的尾纤(41)与多芯光纤(3)的一端熔融拉锥耦合连接,多芯光纤(3)的另一端与阶跃多模光纤(2)的一端常规同轴熔接,阶跃多模光纤(2)的另一端经熔融加工制备成半径R的近似半圆球结构(22),激光光源(4)发出激光,在阶跃多模光纤(2) 的纤芯(21)中激发出类贝塞尔光束(23),半圆球结构(22)汇聚类贝塞尔光束(23)在空间干涉形成阵列三维光势阱(24)。A multi-core fiber-like Bessel beam array optical tweezers, comprising a multi-core fiber (3), a step multi-mode fiber (2) and a laser light source (4), a pigtail (41) of the laser light source (4) and a multi-mode fiber One end of the core optical fiber (3) is fused and taper-connected, the other end of the multi-core optical fiber (3) is conventionally coaxially spliced with one end of the stepped multimode optical fiber (2), and the other end of the stepped multimode optical fiber (2) is fused together. An approximate hemispherical structure (22) with a radius R is prepared by melt processing, and a laser light source (4) emits a laser to excite a Bessel-like beam (23) in the core (21) of the step multimode fiber (2), The hemispherical structure (22) converges the Bessel-like beams (23) and interferes in space to form an array of three-dimensional optical potential wells (24).

多芯光纤(3)的纤芯(31)的数量大于等于2,纤芯(31)的分布不固定,纤芯(31) 的分布可以是对称的,也可以是不对称的,不同纤芯(31)分布带来不同光阱数量与位置。The number of cores (31) of the multi-core optical fiber (3) is greater than or equal to 2, and the distribution of the cores (31) is not fixed. (31) The distribution brings about different numbers and positions of optical traps.

阶跃多模光纤(2)为芯径大于多芯光纤的纤芯距的阶跃折射率分布的多模光纤,阶跃多模光纤(2)的长度范围为200-500μm,近似半圆球结构(22)的半径R的范围为50-90μm,阶跃多模光纤的长度及阶跃多模光纤一端熔融拉锥形状的调整,实现光势阱和捕获粒子数量的变更,实现微小粒子的显微精细操作。The step multimode optical fiber (2) is a multimode optical fiber with a step refractive index distribution whose core diameter is greater than the core distance of the multi-core optical fiber, and the length of the step multimode optical fiber (2) is in the range of 200-500 μm and has an approximate hemispherical structure. (22) The range of the radius R is 50-90 μm. The length of the step multimode fiber and the shape of the melting taper at one end of the step multimode fiber are adjusted to realize the change of the optical potential well and the number of trapped particles, and realize the display of tiny particles. Micro fine operation.

通过熔接电流时间的控制,控制近似半圆球结构(22)的形状。By controlling the welding current time, the shape of the approximately hemispherical structure (22) is controlled.

一种多芯光纤类贝塞尔光束阵列光镊的制作过程为:The manufacturing process of a multi-core fiber-like Bessel beam array optical tweezers is as follows:

步骤1,激光光源尾纤(41)与五芯光纤(3)光源耦合:结合图1和图4采用熔融拉锥耦合,将激光光源的尾纤(41)与五芯光纤(3)拉锥耦合,实现激光光源(4)功率的耦合与分配调整。Step 1: Coupling the laser light source pigtail (41) with the five-core optical fiber (3) light source: using fusion taper coupling in combination with Figures 1 and 4, the laser light source pigtail (41) and the five-core optical fiber (3) are tapered Coupling to realize the coupling and distribution adjustment of the power of the laser light source (4).

步骤2,类贝塞尔光束激发:结合图1和图3,为了能够在阶跃多模光纤(2)中激发类贝塞尔光束(23),将多芯光纤(3)与阶跃多模光纤(2)常规同轴熔接,取阶跃多模长度L,在阶跃多模光纤纤芯(21)中激发出类贝塞尔光束(23)。Step 2, Bessel-like beam excitation: Combined with Fig. 1 and Fig. 3, in order to excite Bessel-like beam (23) in the step multimode fiber (2), the multi-core fiber (3) is combined with the step multimode fiber (2). The mode fiber (2) is conventionally coaxially spliced, and the step multimode length L is taken, and a Bessel-like beam (23) is excited in the step multimode fiber core (21).

步骤3,光纤锥尖透镜(22)制备:结合图3,采用熔融加工制备成半径为R的半圆球结构(22)锥尖形成透镜,通过熔接电流时间的控制,控制锥尖透镜的形状。Step 3, preparation of optical fiber cone-tip lens (22): with reference to FIG. 3, a hemispherical structure (22) with a radius of R is prepared by fusion processing to form a cone-tip lens, and the shape of the cone-tip lens is controlled by controlling the welding current time.

步骤4,三维阵列捕获实验:将整个系统连接完毕之后,打开光源(4),激光光源通过拉锥区耦合进入多芯光纤(3),多芯光纤(3)与阶跃多模光纤(2)常规同轴熔接,在阶跃多模光纤纤芯(21)中激发类贝塞尔光束(23),该类贝塞尔光束(23)经多模光纤半圆形结构(22)汇聚后干涉形成三维光学势阱(24),达到实现微小粒子的三维阵列捕获的目的。Step 4, three-dimensional array capture experiment: after the entire system is connected, turn on the light source (4), the laser light source is coupled into the multi-core fiber (3) through the taper region, the multi-core fiber (3) and the step multi-mode fiber (2) ) conventional coaxial fusion splicing, in which a Bessel-like beam (23) is excited in the stepped multimode fiber core (21), and the Bessel-like beam (23) is converged by the multimode fiber semicircular structure (22) The interference forms a three-dimensional optical potential well (24), so as to achieve the purpose of capturing tiny particles in a three-dimensional array.

实施例2Example 2

本发明涉及光学捕获领域,具体说是一种多芯光纤类贝塞尔光束阵列光镊。The invention relates to the field of optical capture, in particular to a multi-core fiber-like Bessel beam array optical tweezers.

光镊是利用光强分布的梯度力和散射力俘获和操纵粒子的工具。由美国贝尔实验室的 Askin及其同事与1986年首次提出(Optics Letters,18(5):288-290,1986),一种基于单光束激光的三维光学势阱,用于实现对微小粒子的三维控制,因此光束可实现空间对微小粒子的夹持,得名“光镊”。此后,光镊技术发展迅速,成为重要的研究技术手段,使其广泛应用于各种微小粒子的操作领域中,从数百微米的粒子到纳米粒子,从活体细胞到DNA生物大分子链都可以用光镊进行捕获和操作。Optical tweezers are tools for trapping and manipulating particles using the gradient force and scattering force of light intensity distribution. It was first proposed by Askin and his colleagues at Bell Labs in the United States in 1986 (Optics Letters, 18(5): 288-290, 1986), a three-dimensional optical potential well based on a single-beam laser, which is used to realize the detection of tiny particles. Three-dimensional control, so the light beam can realize the clamping of tiny particles in space, so it is named "optical tweezers". Since then, optical tweezers technology has developed rapidly and has become an important research technique, making it widely used in the field of manipulation of various tiny particles, ranging from particles of hundreds of microns to nanoparticles, from living cells to DNA biological macromolecular chains. Capture and manipulate with optical tweezers.

由于传统光镊系统基于光学显微系统其体积较大、在结构上缺乏灵活性、操作自由度较小。光纤作为波导介质,其柔性特征更适合于在复杂空间中进行微操作。与常规光镊系统相比,光纤光镊因其具有结构简单、价格低廉、操作灵活等特点而得到发展。Because the traditional optical tweezers system is based on the optical microscope system, it is bulky, lacks flexibility in structure, and has less freedom of operation. As a waveguide medium, optical fiber is more suitable for micro-manipulation in complex space due to its flexible characteristics. Compared with conventional optical tweezers systems, fiber optic tweezers have been developed due to their simple structure, low price, and flexible operation.

由多光纤光镊发展至阵列光纤光镊技术以来,产生了多种光纤光镊系统。例如,2008年公开了名为“集成于单根光纤的多光镊”,公开号CN101251620,通过调整纤芯的几何排布结构,可实现在不同位置几何排列的多个微小粒子的同时捕获,同时使光镊的捕获性能得到极大的改善;2010年,陆续公开了公开号为CN101893736A的“基于阵列芯光纤的轴向阵列光镊及光动力控制方法”,该轴向阵列光镊在光纤末端形成的光学势阱呈正八面体结构,正八面体的顶点处形成光学势阱,通过调节压电陶瓷驱动装置的驱动电路改变阵列芯光纤方向位移进行传输光束的相位控制,实现功率分配与调整,控制该轴向阵列光镊光阱力分布;公开号为CN101907742A的“基于多芯保偏光纤的阵列式光镊及其制备方法”,该阵列式光镊可以在光纤端形成致密的干涉网格光场阵列,在相干加强点形成光学势阱对粒子实现筛选等功能。这些光镊多能实现多粒子的捕获操作等功能,但很少有可进行亚微米级粒子三维阵列捕获和操作的光镊。Since the development of multi-fiber optical tweezers to array fiber optical tweezers technology, a variety of optical fiber optical tweezers systems have been produced. For example, in 2008, a publication entitled "Multi-optical tweezers integrated in a single fiber" was published with the publication number CN101251620. By adjusting the geometrical arrangement of the fiber core, the simultaneous capture of multiple tiny particles geometrically arranged at different positions can be achieved. At the same time, the capture performance of the optical tweezers has been greatly improved; in 2010, the publication number CN101893736A "Axial Array Optical Tweezers and Optical Dynamic Control Method Based on Array Core Fiber" was published one after another. The optical potential well formed at the end has a regular octahedral structure, and the optical potential well is formed at the vertex of the regular octahedron. By adjusting the driving circuit of the piezoelectric ceramic driving device, the direction displacement of the array core fiber is changed to control the phase of the transmitted beam, and the power distribution and adjustment are realized. Control the optical trap force distribution of the axial array optical tweezers; the publication number is CN101907742A "Array optical tweezers based on multi-core polarization-maintaining fibers and preparation method thereof", the array optical tweezers can form a dense interference grid at the fiber end The optical field array forms an optical potential well at the coherent enhancement point to screen particles and other functions. Most of these optical tweezers can achieve functions such as multi-particle capture operation, but there are few optical tweezers that can capture and operate three-dimensional arrays of sub-micron particles.

本发明的目的在于提出一种节约了物理空间的同时,实现了单光纤三维阵列捕获的基于光纤类贝塞尔光束的单光纤阵列光镊。The purpose of the present invention is to provide a single-fiber array optical tweezers based on a fiber-like Bessel beam that realizes capture by a single-fiber three-dimensional array while saving physical space.

本发明的目的是这样实现的:The object of the present invention is achieved in this way:

一种多芯光纤类贝塞尔光束阵列光镊,包括多芯光纤(3)阶跃多模光纤(2)和激光光源(4),其特征是:激光光源(4)的尾纤(41)与多芯光纤(3)的一端熔融拉锥耦合连接,多芯光纤(3)的另一端与阶跃多模光纤(2)常规同轴熔接,在阶跃多模光纤(2)的纤芯(21) 中激发出类贝塞尔光束(23),将一定长度L的阶跃多模光纤(2)的另一端经熔融加工制备成半径R的近似半圆球结构(22),通过半圆球结构(22)汇聚类贝塞尔光束(23)在空间干涉形成阵列三维光势阱(24)。A multi-core fiber-like Bessel beam array optical tweezers, comprising a multi-core fiber (3) a step-by-step multi-mode fiber (2) and a laser light source (4), characterized in that: a pigtail (41) of the laser light source (4) ) is fused and taper-coupled to one end of the multi-core optical fiber (3), and the other end of the multi-core optical fiber (3) is conventionally coaxially spliced with the stepped multi-mode fiber (2). A Bessel-like beam (23) is excited in the core (21), and the other end of the step multi-mode optical fiber (2) with a certain length L is prepared into an approximate hemispherical structure (22) with a radius R by melting and processing, and the semicircular The spherical structure (22) converges the Bessel-like beams (23) and interferes in space to form an array of three-dimensional optical potential wells (24).

多芯光纤(3)其纤芯(31)的数量大于等于2。The number of cores (31) of the multi-core optical fiber (3) is greater than or equal to two.

阶跃多模光纤(2)为芯径大于多芯光纤的纤芯距的阶跃折射率分布的多模光纤,其长度 L可取200-500μm,另一端通过熔融制成的近似半圆球结构(22)的半径R可取50-90μm。The step multimode fiber (2) is a multimode fiber with a step refractive index distribution whose core diameter is greater than the core distance of the multi-core fiber. 22) The radius R may be 50-90 μm.

激光光源(4)的尾纤与多芯光纤(3)的一端熔融拉锥耦合,实现功率的耦合与分配调整。The pigtail of the laser light source (4) is fused and taper-coupled with one end of the multi-core optical fiber (3), so as to realize power coupling and distribution adjustment.

本发明的优点和特点在于:The advantages and characteristics of the present invention are:

展示了一种基于类贝塞尔光束的新型全光纤阵列光镊;demonstrated a novel all-fiber array optical tweezers based on Bessel-like beams;

利用多芯光纤与阶跃多模光纤同轴熔接在阶跃多模光纤中激发的类贝塞尔光束干涉形成致密的三维光学势阱,可用于对多个微小粒子的批量操作和筛选,实现特定位置的三维阵列排列;A compact three-dimensional optical potential well is formed by coaxially splicing a multi-core fiber and a step multi-mode fiber, and the Bessel-like beam excited in the step multi-mode fiber interferes. 3D array arrangement at a specific location;

基于多芯光纤与阶跃多模光纤的类贝塞尔光束阵列光镊可通过对多芯光纤纤芯数目、阶跃多模光纤的长度及阶跃多模光纤一端熔融拉锥形状的调整,实现光势阱和捕获粒子数量的变更,实现微小粒子的显微精细操作,使其在生物医学研究领域有广泛的应用价值。Bessel-like beam array optical tweezers based on multi-core fiber and step multi-mode fiber can be adjusted by adjusting the number of multi-core fiber cores, the length of the step multi-mode fiber, and the shape of the fused taper at one end of the step multi-mode fiber. It can realize the change of the number of optical potential wells and trapped particles, and realize the microscopic and fine operation of tiny particles, which makes it have a wide range of application value in the field of biomedical research.

下面结合附图举例对本发明进行更为详细的论述:The present invention will be discussed in more detail below in conjunction with the accompanying drawings:

本发明的目的在于提出一种节约了物理空间的同时,实现了单光纤三维阵列捕获的基于光纤类贝塞尔光束的单光纤阵列光镊。这种单光纤阵列光镊展示了一种基于类贝塞尔光束的新型全光纤阵列光镊;同时,可用于对多个微小粒子的批量操作和筛选,实现特定位置的三维阵列排列,使其在生物医学研究领域有广泛的应用价值。The purpose of the present invention is to provide a single-fiber array optical tweezers based on a fiber-like Bessel beam that realizes capture by a single-fiber three-dimensional array while saving physical space. This single-fiber array optical tweezers demonstrates a new type of all-fiber array optical tweezers based on Bessel-like beams; at the same time, it can be used for batch operation and screening of multiple tiny particles to achieve a three-dimensional array arrangement at a specific location, making it It has a wide range of application value in the field of biomedical research.

一种多芯光纤类贝塞尔光束阵列光镊,包括多芯光纤(3)阶跃多模光纤(2)和激光光源(4),其特征是:激光光源(4)的尾纤(41)与多芯光纤(3)的一端熔融拉锥耦合连接,多芯光纤(3)的另一端与阶跃多模光纤(2)常规同轴熔接,在阶跃多模光纤(2)的纤芯(21) 中激发出类贝塞尔光束(23),将一定长度L的阶跃多模光纤(2)的另一端经熔融加工制备成半径R的近似半圆球结构(22),通过半圆球结构(22)汇聚类贝塞尔光束(23)在空间干涉形成阵列三维光势阱(24)。A multi-core fiber-like Bessel beam array optical tweezers, comprising a multi-core fiber (3) a step-by-step multi-mode fiber (2) and a laser light source (4), characterized in that: a pigtail (41) of the laser light source (4) ) is fused and taper-coupled to one end of the multi-core optical fiber (3), and the other end of the multi-core optical fiber (3) is conventionally coaxially spliced with the stepped multi-mode fiber (2). A Bessel-like beam (23) is excited in the core (21), and the other end of the step multi-mode optical fiber (2) with a certain length L is prepared into an approximate hemispherical structure (22) with a radius R by melting and processing, and the semicircular The spherical structure (22) converges the Bessel-like beams (23) and interferes in space to form an array of three-dimensional optical potential wells (24).

所述的多芯光纤(3)其纤芯(31)的数量大于等于2。The number of cores (31) of the multi-core optical fiber (3) is greater than or equal to two.

所述的阶跃多模光纤(2)为芯径大于多芯光纤的纤芯距的阶跃折射率分布的多模光纤,其长度L可取200-500μm,另一端通过熔融制成的近似半圆球结构(22)的半径R可取50-90μm。The step multimode optical fiber (2) is a multimode optical fiber with a step refractive index distribution whose core diameter is greater than the core distance of the multi-core optical fiber. The radius R of the spherical structure (22) may be 50-90 μm.

所述的激光光源(4)的尾纤与多芯光纤(3)的一端熔融拉锥耦合,实现功率的耦合与分配调整。The pigtail of the laser light source (4) is fused and taper-coupled with one end of the multi-core optical fiber (3), so as to realize power coupling and distribution adjustment.

图1多芯光纤类贝塞尔光束阵列光镊结构及原理示意图(以五芯光纤为例)。其中(1) 为可实现阵列捕获的单光纤类贝塞尔阵列光镊,(2)为大芯径阶跃多模光纤,(3)为多芯光纤,(4)为激光光源,(22)为通过熔融制成的半径为R的半球形透镜。激光光源(4)尾纤与多芯光纤(3)一端通过熔融拉锥耦合,多芯光纤(3)另一端与阶跃多模光纤(2)常规同轴熔接,以激发阶跃多模光纤中的类贝塞尔光束,类贝塞尔光束通过阶跃多模光纤一端的半球形透镜(22)在空间干涉构成阵列光阱最终实现三维阵列捕获。Figure 1 is a schematic diagram of the structure and principle of a multi-core fiber-like Bessel beam array optical tweezers (taking a five-core fiber as an example). Among them, (1) is a single-fiber Bessel-like array optical tweezers that can realize array capture, (2) is a large-core step multimode fiber, (3) is a multi-core fiber, (4) is a laser light source, and (22) ) is a hemispherical lens of radius R made by melting. One end of the pigtail fiber of the laser light source (4) and the multi-core optical fiber (3) are coupled by fusion taper, and the other end of the multi-core optical fiber (3) is conventionally coaxially spliced with the step multi-mode fiber (2) to excite the step multi-mode fiber. In the Bessel-like beam, the Bessel-like beam forms an array optical trap through spatial interference of a hemispherical lens (22) at one end of the step multimode fiber, and finally realizes three-dimensional array capture.

图2(a)-(c)多芯光纤剖面图,其中图2(a)为双芯,图2(b)为四芯,图2(c)为五芯。纤芯的分布可以是对称的,也可以是不对称的,不同纤芯分布带来不同光阱数量与位置。Figures 2(a)-(c) are cross-sectional views of multi-core optical fibers, wherein Figure 2(a) is a double-core, Figure 2(b) is a four-core, and Figure 2(c) is a five-core. The distribution of the fiber cores can be symmetrical or asymmetrical, and different core distributions bring about different numbers and positions of optical traps.

图3为多芯光纤类贝塞尔光束阵列光镊的光纤探头示意图。多芯光纤(2)与阶跃多模光纤(3)常规同轴熔接以激发阶跃多模中的类贝塞尔光束。阶跃多模(3)的光纤长度为L,其另一端熔融制成半径为R的半球形透镜(22),类贝塞尔光束通过球形透镜在空间汇聚干涉形成阵列光阱。FIG. 3 is a schematic diagram of a fiber probe of a multi-core fiber Bessel beam array optical tweezers. The multicore fiber (2) is conventionally coaxially spliced with the step multimode fiber (3) to excite Bessel-like beams in the step multimode. The fiber length of the step multimode (3) is L, and the other end of the fiber is fused to form a hemispherical lens (22) with a radius R, and the Bessel-like beams converge and interfere in space through the spherical lens to form an array optical trap.

图4为激光光源尾纤与五芯光纤熔融拉锥耦合结构示意图。通过熔融拉锥耦合可实现激光光源(4)功率的耦合与分配调整。Figure 4 is a schematic diagram of the coupling structure of the laser light source pigtail and the five-core optical fiber fusion taper. The coupling and distribution adjustment of the power of the laser light source (4) can be realized through the fusion taper coupling.

结合图1实现这种三维阵列捕获的单光纤类贝塞尔光镊(1),主要包括多芯光纤(3)阶跃多模光纤(2)和激光光源(4)。激光光源(4)的尾纤(41)与多芯光纤(3)的一端熔融拉锥耦合连接,多芯光纤(3)的另一端与阶跃多模光纤(2)常规同轴熔接,在阶跃多模光纤(2)的纤芯(21)中激发出类贝塞尔光束(23),阶跃多模光纤(2)的另一端经熔融加工制备成半径为R的半圆球结构(22),通过半圆球结构(22)汇聚类贝塞尔光束(23)在空间中干涉形成阵列三维光势阱(24)。The single-fiber Bessel-like optical tweezers ( 1 ) for realizing such three-dimensional array capture with reference to FIG. 1 mainly include a multi-core optical fiber ( 3 ), a step-step multi-mode optical fiber ( 2 ) and a laser light source ( 4 ). The pigtail (41) of the laser light source (4) is connected to one end of the multi-core optical fiber (3) by fusion and taper fusion, and the other end of the multi-core optical fiber (3) is conventionally coaxially spliced with the step multi-mode optical fiber (2). A Bessel-like beam (23) is excited in the core (21) of the step multimode fiber (2), and the other end of the step multimode fiber (2) is melt-processed to prepare a hemispherical structure with a radius R ( 22), by converging Bessel-like beams (23) through a hemispherical structure (22) and interfering in space to form an array of three-dimensional optical potential wells (24).

本实施方式的单光纤光镊的制作过程:The manufacturing process of the single-fiber optical tweezers of this embodiment:

步骤1,激光光源尾纤(41)与五芯光纤(3)光源耦合:结合图1和图4采用熔融拉锥耦合,将激光光源的尾纤(41)与五芯光纤(3)拉锥耦合,实现激光光源(4)功率的耦合与分配调整。Step 1: Coupling the laser light source pigtail (41) with the five-core optical fiber (3) light source: using fusion taper coupling in combination with Figures 1 and 4, the laser light source pigtail (41) and the five-core optical fiber (3) are tapered Coupling to realize the coupling and distribution adjustment of the power of the laser light source (4).

步骤2,类贝塞尔光束激发:结合图1和图3,为了能够在阶跃多模光纤(2)中激发类贝塞尔光束(23),将多芯光纤(3)与阶跃多模光纤(2)常规同轴熔接,取阶跃多模长度L,在阶跃多模光纤纤芯(21)中激发出类贝塞尔光束(23)。Step 2, Bessel-like beam excitation: Combined with Fig. 1 and Fig. 3, in order to excite Bessel-like beam (23) in the step multimode fiber (2), the multi-core fiber (3) is combined with the step multimode fiber (2). The mode fiber (2) is conventionally coaxially spliced, and the step multimode length L is taken, and a Bessel-like beam (23) is excited in the step multimode fiber core (21).

步骤3,光纤锥尖透镜(22)制备:结合图3,采用熔融加工制备成半径为R的半圆球结构(22)锥尖形成透镜,通过熔接电流时间的控制,控制锥尖透镜的形状。Step 3, preparation of optical fiber cone-tip lens (22): with reference to FIG. 3, a hemispherical structure (22) with a radius of R is prepared by fusion processing to form a cone-tip lens, and the shape of the cone-tip lens is controlled by controlling the welding current time.

步骤4,三维阵列捕获实验:将整个系统连接完毕之后,打开光源(4),激光光源通过拉锥区耦合进入多芯光纤(3),多芯光纤(3)与阶跃多模光纤(2)常规同轴熔接,在阶跃多模光纤纤芯(21)中激发类贝塞尔光束(23),该类贝塞尔光束(23)经多模光纤半圆形结构(22)汇聚后干涉形成三维光学势阱(24),达到实现微小粒子的三维阵列捕获的目的。Step 4, three-dimensional array capture experiment: after the entire system is connected, turn on the light source (4), the laser light source is coupled into the multi-core fiber (3) through the taper region, the multi-core fiber (3) and the step multi-mode fiber (2) ) conventional coaxial fusion splicing, in which a Bessel-like beam (23) is excited in the stepped multimode fiber core (21), and the Bessel-like beam (23) is converged by the multimode fiber semicircular structure (22) The interference forms a three-dimensional optical potential well (24), so as to achieve the purpose of capturing tiny particles in a three-dimensional array.

Claims (1)

1. The utility model provides a multicore optic fibre class Bessel beam array optical tweezers, includes multicore optic fibre (3), step multimode fiber (2) and laser source (4), its characterized in that: a tail fiber (41) of a laser light source (4) is connected with one end of a multi-core fiber (3) in a fused biconical coupling mode, the other end of the multi-core fiber (3) is conventionally and coaxially welded with one end of a step multimode fiber (2) with a certain length, a Bessel-like light beam is excited in the step multimode fiber, the other end of the step multimode fiber (2) is prepared into an approximate semi-spherical structure (22) with a radius R through fusion processing, and the Bessel-like light beam is converged through the semi-spherical structure to form a multi-point array three-dimensional potential well (24) through interference in space;
the number of fiber cores (31) of the multi-core optical fiber (3) is more than or equal to 2, the distribution of the fiber cores (31) is not fixed, and different fiber core (31) distribution brings different light traps in number and positions;
the step multimode fiber (2) is a multimode fiber with the core diameter larger than the core distance of the multi-core fiber and the step refractive index distribution, and the length range of the step multimode fiber (2) is 200-500 mu m so as to form a compact space multi-point array three-dimensional potential well;
the shape of the approximate semi-sphere structure (22) of the semi-sphere lens is controlled by controlling the welding current time, and the radius R of the semi-sphere structure (22) ranges from 50 to 90 mu m.
And the tail fiber of the laser light source (4) is fused and tapered with one end of the multi-core fiber to be coupled, so that the power coupling and distribution adjustment are realized.
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