CN108873171B - Multicore optical fiber Bessel-like beam array optical tweezers - Google Patents
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- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B6/00—Light guides; Structural details of arrangements comprising light guides and other optical elements, e.g. couplings
- G02B6/24—Coupling light guides
- G02B6/255—Splicing of light guides, e.g. by fusion or bonding
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- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B6/00—Light guides; Structural details of arrangements comprising light guides and other optical elements, e.g. couplings
- G02B6/02—Optical fibres with cladding with or without a coating
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- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B6/00—Light guides; Structural details of arrangements comprising light guides and other optical elements, e.g. couplings
- G02B6/02—Optical fibres with cladding with or without a coating
- G02B6/02042—Multicore optical fibres
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- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B6/00—Light guides; Structural details of arrangements comprising light guides and other optical elements, e.g. couplings
- G02B6/24—Coupling light guides
- G02B6/255—Splicing of light guides, e.g. by fusion or bonding
- G02B6/2552—Splicing of light guides, e.g. by fusion or bonding reshaping or reforming of light guides for coupling using thermal heating, e.g. tapering, forming of a lens on light guide ends
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- G21K—TECHNIQUES FOR HANDLING PARTICLES OR IONISING RADIATION NOT OTHERWISE PROVIDED FOR; IRRADIATION DEVICES; GAMMA RAY OR X-RAY MICROSCOPES
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Abstract
A multi-core optical fiber Bessel beam array optical tweezers belongs to the technical field of optical trapping. The optical fiber comprises a multi-core optical fiber, a step multimode optical fiber and a laser light source, wherein a tail fiber of the laser light source is connected with one end of the multi-core optical fiber in a melting taper coupling mode, the other end of the multi-core optical fiber is in conventional coaxial fusion welding with one end of the step multimode optical fiber, and the other end of the step multimode optical fiber is prepared into an approximate semi-sphere structure with the radius R through melting processing. The invention relates to a novel all-fiber array optical tweezers based on Bessel-like light beams, which can be used for batch operation and screening of a plurality of tiny particles and realizes three-dimensional array arrangement of specific positions; the change of the quantity of the light potential well and the quantity of the captured particles can be realized by adjusting the number of the fiber cores of the multi-core fiber, the length of the step multimode fiber and the fused biconical taper shape of one end of the step multimode fiber, and the microscopic fine operation of the tiny particles is realized, so that the method has wide application value in the field of biomedical research.
Description
Technical Field
The invention belongs to the technical field of optical trapping, and particularly relates to multi-core optical fiber Bessel beam array optical tweezers.
Background
Optical tweezers are tools that use the gradient and scattering forces of light intensity distribution to capture and manipulate particles. The three-dimensional optical potential well based on single-beam laser is proposed for the first time in 1986 by Askin and colleagues in Bell laboratories of America (Optics Letters,18(5): 288-. Since then, the optical tweezers technology has been rapidly developed and becomes an important research technique, so that the optical tweezers can be widely applied to the field of operation of various kinds of tiny particles, from particles of hundreds of micrometers to nanoparticles, and from living cells to DNA biological macromolecule chains, and can be used for capture and operation.
Because the traditional optical tweezers system is based on an optical microscopy system, the volume is large, the structure lacks flexibility, and the operation freedom degree is small. The optical fiber is used as a waveguide medium, and the flexible characteristic of the optical fiber is more suitable for micro-operation in a complex space. Compared with the conventional optical tweezers system, the optical tweezers of the optical fiber is developed due to the characteristics of simple structure, low price, flexible operation and the like.
Since the development of multi-fiber optical tweezers to array fiber optical tweezers technology, various fiber optical tweezers systems have been produced. For example, 2008 discloses multi-optical tweezers integrated on a single optical fiber, and the publication number CN101251620 can realize simultaneous capture of multiple small particles geometrically arranged at different positions by adjusting the geometric arrangement structure of the fiber core, and meanwhile, the capture performance of the optical tweezers is greatly improved; in 2010, an axial array optical tweezers and a photodynamic control method based on an array core fiber are successively disclosed, wherein the axial array optical tweezers have an octahedral structure with an optical potential well formed at the tail end of the fiber, the optical potential well is formed at the vertex of the octahedral structure, and the phase control of light beam transmission is performed by adjusting the drive circuit of the piezoelectric ceramic drive device to change the direction displacement of the array core fiber, so as to realize power distribution and adjustment and control the optical trapping force distribution of the axial array optical tweezers; the patent publication No. CN101907742A discloses an array type optical tweezers based on multi-core polarization maintaining optical fiber and a preparation method thereof, the array type optical tweezers can form a compact interference grid optical field array at the end of the optical fiber, and optical potential wells are formed at coherent reinforcing points to realize the functions of particle screening and the like. These optical tweezers can realize functions such as multi-particle capture operation, but there are few optical tweezers capable of performing capture and operation of submicron particle three-dimensional arrays.
Disclosure of Invention
Aiming at the existing invention, the invention provides the single fiber array optical tweezers based on the optical fiber Bessel beams, which saves the physical space and realizes the single fiber three-dimensional array capture.
In order to achieve the purpose, the multi-core fiber Bessel-like beam array optical tweezers disclosed by the invention comprise a multi-core fiber (3), a step multimode fiber (2) and a laser source (4), wherein a tail fiber (41) of the laser source (4) is connected with one end of the multi-core fiber (3) in a melting and tapering coupling manner, the other end of the multi-core fiber (3) is conventionally and coaxially welded with one end of the step multimode fiber (2), and the other end of the step multimode fiber (2) is prepared into an approximate semi-spherical structure (22) with a radius R through melting processing.
The number of cores (31) of the multi-core fiber (3) is not less than 2, and the distribution of the cores (31) is not fixed.
The step-index multimode fiber (2) is a multimode fiber with the core diameter larger than the core distance of the multi-core fiber and the step-index distribution, the length range of the step-index multimode fiber (2) is 200-500 mu m, and the radius R range of the approximate semi-sphere structure (22) is 50-90 mu m.
The shape of the approximate semi-sphere structure (22) is controlled by controlling the welding current time.
The invention has the beneficial effects that:
the invention relates to a novel all-fiber array optical tweezers based on Bessel-like light beams; the multi-core optical fiber and the step multimode optical fiber are coaxially welded in the step multimode optical fiber to excite Bessel-like light beams to interfere to form a compact three-dimensional optical potential well, and the compact three-dimensional optical potential well can be used for batch operation and screening of a plurality of tiny particles and realize three-dimensional array arrangement of a specific position; the Bessel-like beam array optical tweezers based on the multi-core fiber and the step multimode fiber can realize the change of the quantity of the optical potential wells and the quantity of the captured particles and the microscopic fine operation of the tiny particles by adjusting the number of the cores of the multi-core fiber, the length of the step multimode fiber and the fused tapering shape of one end of the step multimode fiber, so that the Bessel-like beam array optical tweezers have wide application value in the field of biomedical research.
Drawings
Fig. 1 is a schematic diagram of a structure and a principle of a multi-core fiber bessel-like beam array optical tweezers (taking a five-core fiber as an example);
FIGS. 2(a) - (c) are cross-sectional views of a multi-core optical fiber, wherein FIG. 2(a) is a dual-core, FIG. 2(b) is a quad-core, and FIG. 2(c) is a five-core;
FIG. 3 is a schematic diagram of a fiber probe of the multi-core fiber Bessel-like beam array optical tweezers;
FIG. 4 is a schematic view of a fused biconical taper coupling structure of a laser source tail fiber and a five-core fiber.
The specific implementation mode is as follows:
the invention is further described with reference to the accompanying drawings in which:
example 1
A multi-core optical fiber Bessel-like light beam array optical tweezers comprises a multi-core optical fiber (3), a step multimode optical fiber (2) and a laser light source (4), wherein a tail fiber (41) of the laser light source (4) is connected with one end of the multi-core optical fiber (3) in a fused biconical coupling mode, the other end of the multi-core optical fiber (3) is in conventional coaxial fusion welding with one end of the step multimode optical fiber (2), the other end of the step multimode optical fiber (2) is prepared into an approximate semi-spherical structure (22) with a radius R through fusion processing, the laser light source (4) emits laser, Bessel-like light beams (23) are excited in a fiber core (21) of the step multimode optical fiber (2), and the semi-spherical structure (22) collects the Bessel-like light beams (23) and forms an array three-.
The number of the fiber cores (31) of the multi-core fiber (3) is more than or equal to 2, the distribution of the fiber cores (31) is not fixed, the distribution of the fiber cores (31) can be symmetrical or asymmetrical, and different fiber core (31) distributions bring different light trap numbers and positions.
The step multimode fiber (2) is a multimode fiber with the core diameter larger than the core distance of the multi-core fiber and the step refractive index distribution, the length range of the step multimode fiber (2) is 200-500 mu m, the range of the radius R of the approximate semi-sphere structure (22) is 50-90 mu m, the length of the step multimode fiber and the adjustment of the fused biconical shape at one end of the step multimode fiber realize the change of the number of optical potential wells and the number of the captured particles and realize the microscopic fine operation of the tiny particles.
The shape of the approximate semi-sphere structure (22) is controlled by controlling the welding current time.
The manufacturing process of the multi-core fiber Bessel-like beam array optical tweezers comprises the following steps:
step 1, coupling a laser source tail fiber (41) with a five-core optical fiber (3) light source: and (3) adopting fused tapering coupling with the combination of the graph 1 and the graph 4 to taper-couple the tail fiber (41) of the laser source and the five-core optical fiber (3) so as to realize the coupling and distribution adjustment of the power of the laser source (4).
Example 2
The invention relates to the field of optical trapping, in particular to multi-core optical fiber Bessel-like beam array optical tweezers.
Optical tweezers are tools that use the gradient and scattering forces of light intensity distribution to capture and manipulate particles. The three-dimensional optical potential well based on single-beam laser is proposed for the first time in 1986 by Askin and colleagues in Bell laboratories of America (Optics Letters,18(5): 288-. Since then, the optical tweezers technology has been rapidly developed and becomes an important research technique, so that the optical tweezers can be widely applied to the field of operation of various kinds of tiny particles, from particles of hundreds of micrometers to nanoparticles, and from living cells to DNA biological macromolecule chains, and can be used for capture and operation.
Because the traditional optical tweezers system is based on an optical microscopy system, the volume is large, the structure lacks flexibility, and the operation freedom degree is small. The optical fiber is used as a waveguide medium, and the flexible characteristic of the optical fiber is more suitable for micro-operation in a complex space. Compared with the conventional optical tweezers system, the optical tweezers of the optical fiber is developed due to the characteristics of simple structure, low price, flexible operation and the like.
Since the development of multi-fiber optical tweezers to array fiber optical tweezers technology, various fiber optical tweezers systems have been produced. For example, 2008 discloses multi-optical tweezers integrated on a single optical fiber, and the publication number CN101251620 can realize simultaneous capture of multiple small particles geometrically arranged at different positions by adjusting the geometric arrangement structure of the fiber core, and meanwhile, the capture performance of the optical tweezers is greatly improved; in 2010, an axial array optical tweezers and a photodynamic control method based on an array core fiber are successively disclosed, wherein the axial array optical tweezers have an octahedral structure with an optical potential well formed at the tail end of the fiber, the optical potential well is formed at the vertex of the octahedral structure, and the phase control of light beam transmission is performed by adjusting the drive circuit of the piezoelectric ceramic drive device to change the direction displacement of the array core fiber, so as to realize power distribution and adjustment and control the optical trapping force distribution of the axial array optical tweezers; the patent publication No. CN101907742A discloses an array type optical tweezers based on multi-core polarization maintaining optical fiber and a preparation method thereof, the array type optical tweezers can form a compact interference grid optical field array at the end of the optical fiber, and optical potential wells are formed at coherent reinforcing points to realize the functions of particle screening and the like. These optical tweezers can realize functions such as multi-particle capture operation, but there are few optical tweezers capable of performing capture and operation of submicron particle three-dimensional arrays.
The invention aims to provide single-fiber array optical tweezers based on optical fiber Bessel beams, which save physical space and realize single-fiber three-dimensional array capture.
The purpose of the invention is realized as follows:
the utility model provides a multicore optic fibre class Bessel beam array optical tweezers, includes multicore optic fibre (3) step multimode fiber (2) and laser light source (4), characterized by: the tail fiber (41) of the laser light source (4) is connected with one end of the multi-core fiber (3) in a fused biconical coupling mode, the other end of the multi-core fiber (3) is conventionally and coaxially welded with the step multimode fiber (2), a Bessel-like light beam (23) is excited in the fiber core (21) of the step multimode fiber (2), the other end of the step multimode fiber (2) with a certain length L is prepared into an approximate semi-sphere structure (22) with a radius R through fusion processing, and the Bessel-like light beam (23) is converged through the semi-sphere structure (22) to form an array three-dimensional light potential well (24) through spatial interference.
The number of cores (31) of the multi-core fiber (3) is 2 or more.
The step-index multimode fiber (2) is a multimode fiber with a step-index distribution, the core diameter of which is larger than the core pitch of the multi-core fiber, the length L of the step-index multimode fiber can be 200-500 mu m, and the radius R of an approximate semi-spherical structure (22) which is formed by melting the other end of the step-index multimode fiber can be 50-90 mu m.
The tail fiber of the laser light source (4) is fused and tapered with one end of the multi-core fiber (3) to realize the power coupling and distribution adjustment.
The invention has the advantages and characteristics that:
the novel all-fiber array optical tweezers based on the Bessel-like light beams are shown;
the multi-core optical fiber and the step multimode optical fiber are coaxially welded in the step multimode optical fiber to excite Bessel-like light beams to interfere to form a compact three-dimensional optical potential well, and the compact three-dimensional optical potential well can be used for batch operation and screening of a plurality of tiny particles and realize three-dimensional array arrangement of a specific position;
the Bessel-like beam array optical tweezers based on the multi-core fiber and the step multimode fiber can realize the change of the quantity of the optical potential wells and the quantity of the captured particles and the microscopic fine operation of the tiny particles by adjusting the number of the cores of the multi-core fiber, the length of the step multimode fiber and the fused tapering shape of one end of the step multimode fiber, so that the Bessel-like beam array optical tweezers have wide application value in the field of biomedical research.
The invention will now be discussed in more detail by way of example with reference to the accompanying drawings in which:
the invention aims to provide single-fiber array optical tweezers based on optical fiber Bessel beams, which save physical space and realize single-fiber three-dimensional array capture. The single fiber array optical tweezers show a novel all-fiber array optical tweezers based on Bessel-like light beams; meanwhile, the method can be used for batch operation and screening of a plurality of micro particles, and the three-dimensional array arrangement of a specific position is realized, so that the method has wide application value in the field of biomedical research.
The utility model provides a multicore optic fibre class Bessel beam array optical tweezers, includes multicore optic fibre (3) step multimode fiber (2) and laser light source (4), characterized by: the tail fiber (41) of the laser light source (4) is connected with one end of the multi-core fiber (3) in a fused biconical coupling mode, the other end of the multi-core fiber (3) is conventionally and coaxially welded with the step multimode fiber (2), a Bessel-like light beam (23) is excited in the fiber core (21) of the step multimode fiber (2), the other end of the step multimode fiber (2) with a certain length L is prepared into an approximate semi-sphere structure (22) with a radius R through fusion processing, and the Bessel-like light beam (23) is converged through the semi-sphere structure (22) to form an array three-dimensional light potential well (24) through spatial interference.
The number of the fiber cores (31) of the multi-core optical fiber (3) is more than or equal to 2.
The step-step multimode fiber (2) is a multimode fiber with the core diameter larger than the core distance of the multi-core fiber and the step-step refractive index distribution, the length L of the step-step multimode fiber can be 200-500 mu m, and the radius R of an approximate semi-spherical structure (22) which is formed by melting the other end of the step-step multimode fiber can be 50-90 mu m.
And the tail fiber of the laser light source (4) is fused and tapered with one end of the multi-core fiber (3) for coupling, so that the power coupling and distribution adjustment are realized.
Fig. 1 is a schematic diagram of a structure and a principle of a multi-core fiber bessel-like beam array optical tweezers (taking a five-core fiber as an example). The optical tweezers comprise (1) single-fiber Bessel array optical tweezers capable of realizing array capture, (2) large-core-diameter step multimode optical fibers, (3) multi-core optical fibers, (4) a laser light source, and (22) a hemispherical lens with the radius of R, wherein the hemispherical lens is manufactured by melting. The tail fiber of the laser light source (4) is coupled with one end of the multi-core fiber (3) through melting tapering, the other end of the multi-core fiber (3) is in conventional coaxial fusion welding with the step multimode fiber (2) to excite the Bessel-like light beam in the step multimode fiber, and the Bessel-like light beam forms an array light trap through spatial interference of a hemispherical lens (22) at one end of the step multimode fiber to finally realize three-dimensional array capture.
Fig. 2(a) - (c) are cross-sectional views of the multi-core optical fiber, wherein fig. 2(a) is a dual core, fig. 2(b) is a quad core, and fig. 2(c) is a five core. The distribution of the cores may be symmetrical or asymmetrical, with different core distributions resulting in different numbers and locations of optical traps.
Fig. 3 is a schematic diagram of a fiber probe of the multi-core fiber bessel-like beam array optical tweezers. The multi-core fiber (2) and the step-multimode fiber (3) are conventionally coaxially fused to excite a Bessel-like beam in the step-multimode. The length of the optical fiber of the step multimode (3) is L, the other end of the optical fiber is melted to be made into a hemispherical lens (22) with the radius of R, and the Bessel-like light beams are converged and interfered in space through the spherical lens to form an array optical trap.
FIG. 4 is a schematic view of a fused biconical taper coupling structure of a laser source tail fiber and a five-core fiber. The power coupling and distribution adjustment of the laser light source (4) can be realized through fused biconical taper coupling.
The single-fiber Bessel optical tweezers (1) for realizing the three-dimensional array capture by combining with the figure 1 mainly comprise a multi-core fiber (3), a step multimode fiber (2) and a laser light source (4). A tail fiber (41) of a laser light source (4) is connected with one end of a multi-core fiber (3) in a fused biconical coupling mode, the other end of the multi-core fiber (3) is conventionally and coaxially welded with a step multimode fiber (2), a Bessel-like light beam (23) is excited in a fiber core (21) of the step multimode fiber (2), the other end of the step multimode fiber (2) is prepared into a semi-spherical structure (22) with the radius of R through fusion processing, and the Bessel-like light beam (23) is converged through the semi-spherical structure (22) to form an array three-dimensional light potential well (24) in a space in an interfering mode.
The manufacturing process of the single fiber optical tweezers of the embodiment comprises the following steps:
step 1, coupling a laser source tail fiber (41) with a five-core optical fiber (3) light source: and (3) adopting fused tapering coupling with the combination of the graph 1 and the graph 4 to taper-couple the tail fiber (41) of the laser source and the five-core optical fiber (3) so as to realize the coupling and distribution adjustment of the power of the laser source (4).
Claims (1)
1. The utility model provides a multicore optic fibre class Bessel beam array optical tweezers, includes multicore optic fibre (3), step multimode fiber (2) and laser source (4), its characterized in that: a tail fiber (41) of a laser light source (4) is connected with one end of a multi-core fiber (3) in a fused biconical coupling mode, the other end of the multi-core fiber (3) is conventionally and coaxially welded with one end of a step multimode fiber (2) with a certain length, a Bessel-like light beam is excited in the step multimode fiber, the other end of the step multimode fiber (2) is prepared into an approximate semi-spherical structure (22) with a radius R through fusion processing, and the Bessel-like light beam is converged through the semi-spherical structure to form a multi-point array three-dimensional potential well (24) through interference in space;
the number of fiber cores (31) of the multi-core optical fiber (3) is more than or equal to 2, the distribution of the fiber cores (31) is not fixed, and different fiber core (31) distribution brings different light traps in number and positions;
the step multimode fiber (2) is a multimode fiber with the core diameter larger than the core distance of the multi-core fiber and the step refractive index distribution, and the length range of the step multimode fiber (2) is 200-500 mu m so as to form a compact space multi-point array three-dimensional potential well;
the shape of the approximate semi-sphere structure (22) of the semi-sphere lens is controlled by controlling the welding current time, and the radius R of the semi-sphere structure (22) ranges from 50 to 90 mu m.
And the tail fiber of the laser light source (4) is fused and tapered with one end of the multi-core fiber to be coupled, so that the power coupling and distribution adjustment are realized.
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| CN109669246B (en) * | 2018-12-27 | 2020-10-30 | 中国电子科技集团公司第三十四研究所 | Array fiber optical tweezers drawing method |
| CN110237875B (en) * | 2019-05-31 | 2020-11-10 | 西安交通大学 | Mark-free living cell detection micro-fluidic chip based on quasi-Bessel optical waveguide structure |
| CN112071462B (en) * | 2020-06-05 | 2022-06-07 | 桂林电子科技大学 | Adjustable single optical fiber particle conveyor |
| CN111653379B (en) * | 2020-06-05 | 2023-07-25 | 桂林电子科技大学 | Nanoparticle conveyor based on multi-fiber optical tweezers |
| CN112068251A (en) * | 2020-09-06 | 2020-12-11 | 桂林电子科技大学 | Optical fiber Bessel light beam optical tweezers and device |
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| AU2003221655A1 (en) * | 2002-04-24 | 2003-11-10 | Alfalight, Inc. | Feedback stabilized multi-mode and method of stabilizing a multi-mode laser |
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