CN108865817A - Gene sequencing reaction device - Google Patents
Gene sequencing reaction device Download PDFInfo
- Publication number
- CN108865817A CN108865817A CN201710318528.7A CN201710318528A CN108865817A CN 108865817 A CN108865817 A CN 108865817A CN 201710318528 A CN201710318528 A CN 201710318528A CN 108865817 A CN108865817 A CN 108865817A
- Authority
- CN
- China
- Prior art keywords
- hole
- fixing seat
- telescopic rod
- support frame
- gene sequencing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6869—Methods for sequencing
Abstract
The present invention relates to gene sequencing technology fields, provide a kind of gene sequencing reaction device；Including fixing seat, rotating turret, reaction small chamber and pressed seat；Reaction small chamber is mounted in fixing seat, and reagent inlet and reagent exit are provided on reaction small chamber；Entrance connecting tube and outlet connecting pipe are fixedly installed on the rotating turret, entrance connecting tube and outlet connecting pipe are used to be pressed on the reaction small chamber and are connected respectively with reagent inlet and reagent exit；Pressed seat includes support frame and telescopic rod, and support frame is mounted in fixing seat, telescopic rod be set on support frame and with support frame elastic connection；One end of rotating turret is rotatably installed in fixing seat, and the bottom end of telescopic rod is used for elastic compression in the other end of rotating turret；The beneficial effects of the invention are as follows：When multiple reaction small chambers thickness not for the moment, the case where capable of guaranteeing good sealing performance, avoid the occurrence of leakage.
Description
Technical field
The present invention relates to gene sequencing technology fields, more particularly, it relates to a kind of gene sequencing reaction device.
Background technique
Gene sequencing technology is to detect nucleic acid by gene sequencer, obtains nucleic acid sequence by data processing.At present
Gene sequencer, carry out sequencing reaction by the way that DNA fragmentation print to be measured to be arranged in the reaction chip of gene sequencer, survey
By reaction runner and print to be measured sequencing reaction occurs for reaction reagent when sequence.Pass through image collecting device after sequencing reaction
Image Acquisition is carried out, then by obtaining gene order after post-processing.
Gene sequencer in the prior art is connected including reaction chip, for the reaction channel with reaction chip
Pipeline needs to compress in pipeline and reaction chip before carrying out sequencing reaction, close between pipeline and reaction chip to realize
Envelope.But since reaction chip needs replacing, and different reaction chips is due to mismachining tolerance, thickness not fully one
Cause, therefore, after replacing reaction chip, then need that manually the pressing force of pipeline is adjusted, to avoid occur leakage or
Occur pressing force it is excessive and the case where cause reaction chip to rupture；Required before each gene sequencing to the pressing force of pipeline into
Row is adjusted, and process is very complicated；And the mode of manual adjustment is merely able to the experience according to operator, to the pressing force of pipeline
The case where being adjusted, still will appear leakage.
Therefore a kind of new gene sequencing reaction device is needed, can realize the adjusting to the pressure of reaction chip automatically,
The case where avoiding the occurrence of leakage or reaction chip rupture.
Summary of the invention
The purpose of the present invention is to provide a kind of gene sequencing reaction devices, it is intended to solve in the prior art pipeline with react
The problem of pressure adjusting between chip is cumbersome, is easy to appear leakage or reaction chip rupture.
In order to realize goal of the invention, a kind of gene sequencing reaction device is theed improvement is that：Including fixing seat, rotation
Frame, reaction small chamber and pressed seat；The reaction small chamber is mounted in fixing seat, and reagent inlet and examination are provided on reaction small chamber
Agent outlet；
Entrance connecting tube and outlet connecting pipe are fixedly installed on the rotating turret, the entrance connecting tube and outlet connecting pipe are used
In being pressed on the reaction small chamber and be connected respectively with the reagent inlet and reagent exit；
The pressed seat includes support frame and telescopic rod, and the support frame is mounted in fixing seat, and the telescopic rod is set
Be placed on support frame and with support frame elastic connection；One end of the rotating turret is rotatably installed in fixing seat, the telescopic rod
Bottom end for elastic compression the rotating turret the other end.
In above-mentioned structure, the pressed seat further includes spring, and pass through aperture is provided on support frame as described above, described
Telescopic rod is inserted into the through hole of support frame；
The telescopic rod bottom has a protrusion, the spring pocket on telescopic rod, and one end of spring withstand on it is described
Support frame on, the other end of spring is withstood on the protrusion of telescopic rod, and the protrusion of the telescopic rod is for being pressed on rotation
On the other end of frame.
In above-mentioned structure, the through hole of support frame as described above is stepped hole, which includes that first through hole and second are logical
Hole, first through hole and the second through-hole are cylindrical, and the internal diameter of first through hole is less than the internal diameter of the second through-hole；The top of the spring
End is withstood at the step of first through hole and the second through-hole.
It is additionally provided with perforative fixation hole in above-mentioned structure, on support frame as described above, it is fixed that one is provided in the fixation hole
Screw, a threaded hole is provided in the fixing seat, and the lower end of fixing screws is fixed in the threaded hole.
In above-mentioned structure, the upper end of the telescopic rod is provided at least one card slot, and card slot is provided with circlip, described
Circlip prevents telescopic rod from falling from the through hole of support frame for limiting to telescopic rod.
In above-mentioned structure, the gene sequencing reaction device further includes cell mounting plate, and the two of the cell mounting plate
End is fixed on the bottom surface of the fixing seat；
The fixing seat is in square frame-shaped, and fixing seat has opposite installation inner wall, and one end of the rotating turret is rotatably installed in
On the installation inner wall of fixing seat.
In above-mentioned structure, multiple positioning convex platforms are provided on the cell mounting plate, the side of the reaction small chamber is supported
It leans against on the positioning convex platform；
The both ends of the cell mounting plate are provided with spacing block set, and the reaction small chamber is placed between two spacing block sets；Cell peace
The mounting hole of bar shaped is provided on the spacing block set at loading board both ends.
In above-mentioned structure, the rotating turret includes the first side plate, the second side plate and connecting plate, the first side plate and the
Two side plates are parallel, and the both ends of the connecting plate are connected with one end of one end of the first side plate and the second side plate respectively, and first
The other end of the other end of side plate and the second side plate is rotatably installed in fixing seat；The protrusion of the telescopic rod is for being pressed on
On the connecting plate.
In above-mentioned structure, the gene sequencing reaction device further includes connecting tube fixing seat, first side plate and
The notch for installing the connecting tube fixing seat is provided on the inner wall of two side plates.
In above-mentioned structure, the upper surface of the connecting tube fixing seat is provided with the first blind hole, under connecting tube fixing seat
Surface is provided with the second blind hole, and the third being additionally provided in connecting tube fixing seat for being connected to the first blind hole and the second blind hole is logical
Hole；
The outer surface of the entrance connecting tube and outlet connecting pipe is provided with external screw thread, is provided on the inner wall of first blind hole
Internal screw thread compatible with the external screw thread of entrance connecting tube and outlet connecting pipe；A sealing is provided in second blind hole
Circle, and the reagent through-hole being connected with the third through-hole is provided on sealing ring.
From the foregoing, it will be observed that gene sequencing reaction device of the invention can adapt to the reaction small chamber of different-thickness, when multiple anti-
Answer the thickness of cell and for the moment, can not guarantee between entrance connecting tube and the reagent inlet of reaction small chamber, outlet connecting pipe with
Good sealing performance between the reagent exit of reaction small chamber, the case where avoiding the occurrence of leakage, while can also be to avoid due to entering
Mouthful connecting tube and outlet connecting pipe are excessive to the pressure of reaction small chamber, and the problem of cause reaction small chamber to rupture.
Detailed description of the invention
Fig. 1 is the schematic perspective view of gene sequencing reaction device in one embodiment of the invention.
Fig. 2 is the schematic perspective view of pressed seat in one embodiment of the invention.
Fig. 3 is the top view of pressed seat in one embodiment of the invention.
Fig. 4 is diagrammatic cross-section at A-A in Fig. 3.
Fig. 5 is the configuration schematic diagram of gene sequencing reaction device in another embodiment of the present invention.
Fig. 6 is the schematic perspective view of rotating turret in one embodiment of the invention, connecting tube fixing seat.
Fig. 7 is connecting tube fixing seat, the schematic perspective view of entrance connecting tube in one embodiment of the invention.
Fig. 8 is the top view of connecting tube fixing seat and entrance connecting tube in one embodiment of the invention.
Fig. 9 is diagrammatic cross-section at B-B in Fig. 8.
Specific embodiment
In order to make the objectives, technical solutions, and advantages of the present invention clearer, with reference to the accompanying drawings and embodiments, right
The present invention is further elaborated.
The present invention proposes first embodiment, and the present embodiment proposes a kind of gene sequencing reaction device, as shown in Figure 1, institute
The gene sequencing reaction device stated includes fixing seat 10, rotating turret 20, reaction small chamber 30 and pressed seat 40, and the reaction is small
Room 30 is mounted in fixing seat 10, has reaction channel inside reaction small chamber 30, is additionally provided on reaction small chamber 30 and is reacted logical
The reagent inlet and reagent exit that road is connected；Entrance connecting tube 201 and outlet connecting pipe are installed on the rotating turret 20
202, entrance connecting tube 201 and the reagent inlet of reaction small chamber 30 are connected to each other, the reagent of outlet connecting pipe 202 and reaction small chamber 30
Outlet is connected to each other, and the entrance connecting tube 201 and outlet connecting pipe 202 are connected by pipeline with external equipment, is passed through
Entrance connecting tube 201 is passed through reagent into the reaction channel of reaction small chamber 30, and gene sequencing reaction is carried out in reaction channel, and
The reagent after reaction is discharged by reagent exit and outlet connecting pipe 202.
For the pressed seat 40, as shown in Fig. 2, the invention proposes a specific embodiment, the pressed seat 40
Including support frame 401 and telescopic rod 402, wherein for support frame 401 at L shape, one end is rotatably installed in the fixing seat 10
On, specifically, in the present embodiment, support frame as described above 401 includes rotation section 4011 and cantilever portion 4012, the rotation section 4011
It is vertically mounted on the one side edge of the fixing seat 10, one end of rotation section 4011 and fixing seat 10 are rotatably connected, cantilever portion
The other end of 4012 one end and rotation section 4011 vertically connects.The telescopic rod 402 is set on support frame 401, specifically,
The telescopic rod 402 is vertically mounted on the other end of the cantilever portion 4012, and 401 elastic connection of support frame, can be with
Direction on support frame 401 along vertical cantilever portion 4012 moves back and forth；When rotating turret 20 drives entrance connecting tube 201 and outlet
Connecting tube 202 is pressed on reaction small chamber 30, and support frame 401 drives telescopic rod 402 when moving to 20 top position of rotating turret,
The bottom end of telescopic rod 402 is then pressed on the rotating turret 20.Further, for the pressed seat 40, such as Fig. 3, Fig. 4
Shown, the pressed seat 40 further includes a spring 403, and pass through aperture 404, the telescopic rod are provided on support frame as described above 401
In the through hole 404 of 402 insertion support frames 401, the bottom end of telescopic rod 402 is stretched out from through hole 404, and telescopic rod 402
Bottom end has a protrusion 4021；Described 403 sets of spring are on telescopic rod 402, and one end of spring 403 withstands on support frame
On 401, the other end of spring 403 is withstood on the protrusion 4021 of telescopic rod 402, and the protrusion 4021 of the telescopic rod 402 is used
In being pressed on rotating turret 20.In present embodiment, the protrusion 4021 is an inversed taper platform shape structure, with inclined side
Edge can be with the pressure between damped rotation frame 20 and protruding portion 4021.
Reaction small chamber 30 install when, as shown in Figure 1, rotation pressed seat 40 support frame 401, make telescopic rod 402 from turn
The top position of moving frame 20 is removed, and the rotating turret 20 is hereafter rotated, after reaction small chamber 30 is placed in fixing seat 10,
Rotating turret 20 is turned into state shown in Fig. 1, entrance connecting tube 201 is then pressed in the reagent inlet of reaction small chamber 30 at this time
On, outlet connecting pipe 202 is pressed on the reagent exit of reaction small chamber 30；Support frame 401 is rotated again, is located at telescopic rod 402
The protrusion 4021 of the top of rotating turret 20,402 bottom end of telescopic rod is then pressed on rotating turret 20.Due to telescopic rod 402 and branch
It is elastic connection between support 401, the upper end of spring 403 is withstood on support frame 401, and the lower end of spring 403 withstands on protrusion
On 4021, the protrusion 4021 of telescopic rod 402 compresses the spring 403, therefore the protrusion 4021 of telescopic rod 402 is pressed in and turns
Power in moving frame 20, the as tension of spring 403.By this structure, enable gene sequencing reaction device of the invention
The reaction small chamber 30 for adapting to different-thickness, when multiple reaction small chambers 30 thickness not for the moment, can guarantee entrance connecting tube 201
Between the reagent inlet of reaction small chamber 30, good sealing between outlet connecting pipe 202 and the reagent exit of reaction small chamber 30
Performance, the case where avoiding the occurrence of leakage, while can also be reacted to avoid due to entrance connecting tube 201 and 202 pairs of outlet connecting pipe
The pressure of cell 30 is excessive, and the problem of cause reaction small chamber 30 to rupture.Specifically, when reaction small chamber 30 is due to processing
Error, when thickness is less than normal value, the entrance connecting tube 201, outlet connecting pipe 202 are pressed on reaction small chamber 30, are stretched
The protrusion 4021 of contracting bar 402 is pressed on rotating turret 20, and 4021 compressed spring 403 of protrusion of telescopic rod 402, makes spring at this time
403 deformation for generating slightly are pressed on protrusion 4021 on rotating turret 20 under the reaction force of spring 403, rotating turret 20
When entrance connecting tube 201 and outlet connecting pipe 202 then being made to be pressed on the reaction small chamber 30, entrance connecting tube 201 ensure that
Sealing performance between reaction small chamber 30, between outlet connecting pipe 202 and reaction small chamber 30.When the thickness of reaction small chamber 30 is big
In normal value, after reaction small chamber 30 is placed in fixing seat 10, and the protrusion 4021 of telescopic rod 402 is pressed in rotating turret 20
On, the protrusion 4021 of telescopic rod 402 then compressed spring 403, make spring 403 generate biggish deformation, likewise, in bullet at this time
Under the reaction force of spring 403, it is pressed on protrusion 4021 on rotating turret 20, rotating turret 20 is acted in the pressure of protrusion 4021
Under, be pressed on entrance connecting tube 201, outlet connecting pipe 202 on reaction small chamber 30, ensure that entrance connecting tube 201 with react
Sealing performance between cell 30, between outlet connecting pipe 202 and reaction small chamber 30；It can also be connected simultaneously to avoid due to entrance
The pressure of pipe 201 and outlet connecting pipe 202 it is excessive and cause reaction small chamber 30 rupture the problem of.
On the basis of the above embodiments, for the pressed seat 40, as shown in Figure 3, Figure 4, support frame as described above 401
Through hole 404 is stepped hole, which includes first through hole 4041 and the second through-hole 4042, and first through hole 4041 is located at second
4042 top of through-hole, first through hole 4041 and the second through-hole 4042 are cylindrical, and the internal diameter of first through hole 4041 is less than
The internal diameter of second through-hole 4042；When 403 sets of spring on telescopic rod 402, when telescopic rod 402 is located in through hole 404, spring
403 top is then withstood at the step of first through hole 4041 and the second through-hole 4042, and spring 403 is hidden in support by this structure
In the through hole 404 of frame 401, the height of telescopic rod 402 is reduced, keeps the structure of pressed seat 40 more compact.Support frame as described above
It is additionally provided with perforative fixation hole 405 on 401, is provided with a fixing screws 406 in the fixation hole 405, in the fixing seat 10
It is corresponding to be provided with threaded hole, by the effect of fixing screws 406, support frame 401 is mounted in the fixing seat 10.By
In being provided with a step in fixation hole 405, it is reserved with gap between the surface of the step and the nut of fixing screws 406, therefore
When fixing screws 406 are fixed in the fixing seat 10, support frame 401 can be rotated around fixing screws 406, in order to right
Pressed seat 40 is rotated.
In addition, in the above-described embodiment, the upper end setting of the telescopic rod 402 is there are two card slot 407, and card slot
407 are provided with circlip 408, when the top of spring 403 is then withstood at the step of first through hole 4041 and the second through-hole 4042, spring
When 403 bottom end is withstood on the protrusion 4021 of telescopic rod 402, the circlip 408 is then located at the upper surface of support frame 401,
Telescopic rod 402 is limited, prevents telescopic rod 402 from falling from the through hole 404 of support frame 401；Simultaneously as being provided with
Two card slots 407 can be adjusted the position of circlip 408.
For the gene sequencing reaction device, as shown in figure 5, the invention also provides a specific embodiment, it is described
Gene sequencing reaction device further include cell mounting plate 50, cell mounting plate 50 is fixed on the bottom surface of fixing seat 10；It is described
Multiple positioning convex platforms 501 are provided on cell mounting plate 50, the both ends of the cell mounting plate 50 are additionally provided with spacing block set
502, after reaction small chamber 30 is placed on cell mounting plate 50, the reaction small chamber 30 is placed between two spacing block sets 502,
The side of reaction small chamber 30 is then resisted against on the positioning convex platform 501, by positioning convex platform 501 to the position of reaction small chamber 30
It is defined；In addition, the mounting hole 503 of bar shaped is provided on the spacing block set 502 at 50 both ends of cell mounting plate, by locking spiral shell
Nail, cell mounting plate 50 is fixed on the bottom surface of the fixing seat 10, and mounting hole 503 is in bar shaped, can be to cell mounting plate
50 position is adjusted, and enables the position of entrance connecting tube 201 and outlet connecting pipe 202 and reagent inlet and reagent exit
It is connected to each other.Further, the fixing seat 10 is in square frame-shaped, and fixing seat 10 has opposite installation inner wall 101, rotating turret 20
One end be rotatably installed on the installation inner wall 101 of fixing seat 10, when rotating turret 20 towards reaction small chamber 30 direction rotate, enter
After mouth connecting tube 201 and outlet connecting pipe 202 are pressed on reaction small chamber 30, rotating turret 20 is then positioned at the middle part of fixing seat 10
Hollow position.
For the rotating turret 20, as shown in Figure 5, Figure 6, the rotating turret 20 includes the first side plate 203, second side
Plate 204 and connecting plate 205, the first side plate 203 is parallel with the second side plate 204, and the both ends of the connecting plate 205 are respectively with
One end of side plate 203 is connected with one end of the second side plate 204, the other end of the first side plate 203 and the second side plate 204 it is another
One end is fixed in a rotation axis 206, which passes through the effect of bearing 207, is rotatably installed in fixing seat 10, because
This rotating turret 20 can be rotated relative to fixing seat 10.
For the fixed form of the entrance connecting tube 201 and outlet connecting pipe 202, the embodiment described in Fig. 5, Fig. 6
On the basis of, as shown in Figures 6 to 9, the invention proposes a specific embodiment, gene sequencing reaction device further includes that connecting tube is solid
Reservation 60, entrance connecting tube 201 and outlet connecting pipe 202 are inserted into one respectively and are connected and fixed in seat 10, first side plate 203
Prefecture on the inner wall of second side plate 204 is provided with the notch 208 for installing connecting tube fixing seat 60；The connecting tube is fixed
Seat 60 includes fixed part 601 and integrally formed tubular portion 602, and the through-hole 6010 of bar shaped is wherein provided on fixed part 601,
By locking screw, the fixed part 601 of connecting tube fixing seat 60 is mounted on rotating turret 20, when entrance connecting tube 201 and instead
When there is deviation in the reagent exit for answering the reagent inlet of cell 30 deviation or outlet connecting pipe 202 and reaction small chamber 30 occur,
The position of connecting tube fixing seat 60 can be adjusted；When connecting tube fixing seat 60 is fixed on rotating turret 20, connecting tube
The tubular portion 602 of fixing seat 60 is then located in the notch 208.
Further, as shown in figure 9,601 upper surface of fixed part of the connecting tube fixing seat 60 is provided with the first blind hole
6011, the lower surface of the tubular portion 602 is provided with the second blind hole 6022, and the inside of tubular portion 602 is additionally provided with for being connected to
The third through-hole 6023 of first blind hole 6011 and the second blind hole 6022；The entrance connecting tube 201 and outlet connecting pipe 202 it is outer
Surface is provided with external screw thread, and internal screw thread compatible with external screw thread is provided on the inner wall of the first blind hole 6011, is connected by screw thread
The mode connect realizes the fixation of entrance connecting tube 201 and outlet connecting pipe 202；One is provided in second blind hole 6022
Sealing ring 603, and the reagent through-hole 6031 being connected with the third through-hole 6023 is provided on sealing ring 603；Work as connecting tube
When fixing seat 60 is pressed on reaction small chamber 30, reagent of the reagent through-hole 6031 of the sealing ring 603 then with reaction small chamber 30 enters
Mouth or reagent exit are connected, and sealing ring 603 realizes sealing to reagent inlet or reagent exit under the action of pressing force, keep away
Exempt from the case where leakage occur.
The foregoing is merely illustrative of the preferred embodiments of the present invention, is not intended to limit the invention, all in essence of the invention
Made any modifications, equivalent replacements, and improvements etc., should all be included in the protection scope of the present invention within mind and principle.
Claims (10)
1. a kind of gene sequencing reaction device, it is characterised in that：Including fixing seat, rotating turret, reaction small chamber and pressed seat；Institute
It states reaction small chamber to be mounted in fixing seat, reagent inlet and reagent exit is provided on reaction small chamber；
Entrance connecting tube and outlet connecting pipe are fixedly installed on the rotating turret, the entrance connecting tube and outlet connecting pipe are used
In being pressed on the reaction small chamber and be connected respectively with the reagent inlet and reagent exit；
The pressed seat includes support frame and telescopic rod, and the support frame is mounted in fixing seat, and the telescopic rod is set
Be placed on support frame and with support frame elastic connection；One end of the rotating turret is rotatably installed in fixing seat, the telescopic rod
Bottom end for elastic compression the rotating turret the other end.
2. gene sequencing reaction device according to claim 1, it is characterised in that：The pressed seat further includes spring,
Pass through aperture is provided on support frame as described above, the telescopic rod is inserted into the through hole of support frame；
The telescopic rod bottom has a protrusion, the spring pocket on telescopic rod, and one end of spring withstand on it is described
Support frame on, the other end of spring is withstood on the protrusion of telescopic rod, and the protrusion of the telescopic rod is for being pressed on rotation
On the other end of frame.
3. gene sequencing reaction device according to claim 2, it is characterised in that：The through hole of support frame as described above is step
Hole, the stepped hole include first through hole and the second through-hole, and first through hole and the second through-hole are cylindrical, and the internal diameter of first through hole
Less than the internal diameter of the second through-hole；The top of the spring is withstood at the step of first through hole and the second through-hole.
4. gene sequencing reaction device according to claim 1 or 3, it is characterised in that：It is additionally provided on support frame as described above
Perforative fixation hole is provided with a fixing screws in the fixation hole, a threaded hole is provided in the fixing seat, fixing screws
Lower end is fixed in the threaded hole.
5. gene sequencing reaction device according to claim 1 or 3, it is characterised in that：The upper end of the telescopic rod is arranged
There is at least one card slot, and card slot is provided with circlip, the circlip prevents telescopic rod from support for limiting to telescopic rod
It is fallen in the through hole of frame.
6. gene sequencing reaction device according to claim 1, it is characterised in that：The gene sequencing reaction device also wraps
Cell mounting plate is included, the both ends of the cell mounting plate are fixed on the bottom surface of the fixing seat；
The fixing seat is in square frame-shaped, and fixing seat has opposite installation inner wall, and one end of the rotating turret is rotatably installed in
On the installation inner wall of fixing seat.
7. gene sequencing reaction device according to claim 6, it is characterised in that：It is provided on the cell mounting plate more
A positioning convex platform, the side of the reaction small chamber are resisted against on the positioning convex platform；
The both ends of the cell mounting plate are provided with spacing block set, and the reaction small chamber is placed between two spacing block sets；Cell peace
The mounting hole of bar shaped is provided on the spacing block set at loading board both ends.
8. gene sequencing reaction device according to claim 1, it is characterised in that：The rotating turret includes the first side
Plate, the second side plate and connecting plate, the first side plate is parallel with the second side plate, the both ends of the connecting plate respectively with the first side plate
One end be connected with one end of the second side plate, the other end of the other end of the first side plate and the second side plate is rotatably installed in fixation
On seat；The protrusion of the telescopic rod is used to be pressed on the connecting plate.
9. gene sequencing reaction device according to claim 8, it is characterised in that：The gene sequencing reaction device also wraps
It includes connecting tube fixing seat, is provided on the inner wall of first side plate and the second side plate for installing the connecting tube fixing seat
Notch.
10. gene sequencing reaction device according to claim 9, it is characterised in that：The upper table of the connecting tube fixing seat
Face is provided with the first blind hole, and the lower surface of connecting tube fixing seat is provided with the second blind hole, is additionally provided with use in connecting tube fixing seat
In the third through-hole of connection the first blind hole and the second blind hole；
The outer surface of the entrance connecting tube and outlet connecting pipe is provided with external screw thread, is provided on the inner wall of first blind hole
Internal screw thread compatible with the external screw thread of entrance connecting tube and outlet connecting pipe；A sealing is provided in second blind hole
Circle, and the reagent through-hole being connected with the third through-hole is provided on sealing ring.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710318528.7A CN108865817A (en) | 2017-05-08 | 2017-05-08 | Gene sequencing reaction device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710318528.7A CN108865817A (en) | 2017-05-08 | 2017-05-08 | Gene sequencing reaction device |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN108865817A true CN108865817A (en) | 2018-11-23 |
Family
ID=64287290
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201710318528.7A Pending CN108865817A (en) | 2017-05-08 | 2017-05-08 | Gene sequencing reaction device |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN108865817A (en) |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN201080478Y (en) * | 2007-07-03 | 2008-07-02 | 海尔集团公司 | Gene magnification instrument thermal cap compressing apparatus |
| CN101368206A (en) * | 2008-07-16 | 2009-02-18 | 深圳华因康基因科技有限公司 | Sequencing reaction small chamber, gene sequencing reaction bench and gene sequencing system |
| CN202275094U (en) * | 2011-09-30 | 2012-06-13 | 深圳市新益昌自动化设备有限公司 | Test fixture for aluminum electrolytic capacitor |
| CN104924614A (en) * | 2015-06-08 | 2015-09-23 | 浙江大学 | Rotary switching biological 3D printing sprayer for multi-material printing and rotary switching biological 3D printing method |
-
2017
- 2017-05-08 CN CN201710318528.7A patent/CN108865817A/en active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN201080478Y (en) * | 2007-07-03 | 2008-07-02 | 海尔集团公司 | Gene magnification instrument thermal cap compressing apparatus |
| CN101368206A (en) * | 2008-07-16 | 2009-02-18 | 深圳华因康基因科技有限公司 | Sequencing reaction small chamber, gene sequencing reaction bench and gene sequencing system |
| CN202275094U (en) * | 2011-09-30 | 2012-06-13 | 深圳市新益昌自动化设备有限公司 | Test fixture for aluminum electrolytic capacitor |
| CN104924614A (en) * | 2015-06-08 | 2015-09-23 | 浙江大学 | Rotary switching biological 3D printing sprayer for multi-material printing and rotary switching biological 3D printing method |
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