CN108837301B - Micro-bending electrode for artificial cochlea and manufacturing method thereof - Google Patents
Micro-bending electrode for artificial cochlea and manufacturing method thereof Download PDFInfo
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- CN108837301B CN108837301B CN201810435336.9A CN201810435336A CN108837301B CN 108837301 B CN108837301 B CN 108837301B CN 201810435336 A CN201810435336 A CN 201810435336A CN 108837301 B CN108837301 B CN 108837301B
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- 238000004519 manufacturing process Methods 0.000 title claims abstract description 34
- 210000003477 cochlea Anatomy 0.000 title claims abstract description 24
- 238000005452 bending Methods 0.000 title claims abstract description 16
- 230000004936 stimulating effect Effects 0.000 claims abstract description 25
- 210000003128 head Anatomy 0.000 claims abstract description 5
- 229910000566 Platinum-iridium alloy Inorganic materials 0.000 claims description 39
- HWLDNSXPUQTBOD-UHFFFAOYSA-N platinum-iridium alloy Chemical class [Ir].[Pt] HWLDNSXPUQTBOD-UHFFFAOYSA-N 0.000 claims description 39
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 claims description 26
- 239000000741 silica gel Substances 0.000 claims description 20
- 229910002027 silica gel Inorganic materials 0.000 claims description 20
- 238000000576 coating method Methods 0.000 claims description 15
- 238000000137 annealing Methods 0.000 claims description 12
- 238000003466 welding Methods 0.000 claims description 12
- 239000011248 coating agent Substances 0.000 claims description 9
- 238000010622 cold drawing Methods 0.000 claims description 9
- 238000005520 cutting process Methods 0.000 claims description 9
- 238000003698 laser cutting Methods 0.000 claims description 9
- 238000001746 injection moulding Methods 0.000 claims description 8
- 238000000034 method Methods 0.000 claims description 7
- 238000009832 plasma treatment Methods 0.000 claims description 6
- 238000004506 ultrasonic cleaning Methods 0.000 claims description 6
- 239000007943 implant Substances 0.000 claims description 4
- WABPQHHGFIMREM-UHFFFAOYSA-N lead(0) Chemical compound [Pb] WABPQHHGFIMREM-UHFFFAOYSA-N 0.000 claims description 4
- 238000004140 cleaning Methods 0.000 claims description 3
- 238000000227 grinding Methods 0.000 claims description 3
- 238000007689 inspection Methods 0.000 claims description 3
- 238000005096 rolling process Methods 0.000 claims description 3
- 238000002513 implantation Methods 0.000 abstract description 5
- 230000000638 stimulation Effects 0.000 description 10
- 230000000694 effects Effects 0.000 description 5
- 239000003550 marker Substances 0.000 description 2
- 241000237858 Gastropoda Species 0.000 description 1
- 230000003213 activating effect Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 210000000860 cochlear nerve Anatomy 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 238000009792 diffusion process Methods 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 210000005036 nerve Anatomy 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/02—Details
- A61N1/04—Electrodes
- A61N1/05—Electrodes for implantation or insertion into the body, e.g. heart electrode
- A61N1/0526—Head electrodes
- A61N1/0541—Cochlear electrodes
Abstract
The invention discloses a micro-bending electrode of an artificial cochlea and a manufacturing method thereof, wherein the micro-bending electrode comprises an electrode front section, an electrode middle section and an electrode rear section which are sequentially arranged, the electrode front section comprises a flexible electrode head arranged at the forefront part of the electrode front section, a plurality of electrode contacts arranged at equal intervals on the inner bending side of the micro-bending electrode, and a first depth mark, a second depth mark and a third depth mark which are sequentially arranged on the outer bending side of the micro-bending electrode; the middle section of the electrode comprises a first boosting ring, a second boosting ring, an electrode lead fine spiral part and an electrode lead spiral part; the electrode rear section comprises a loop electrode, a loop electrode lead connected with the loop electrode, a stimulating electrode lead connected with an electrode contact and a deconcentrator, wherein slotted holes the number of which is consistent with that of the electrode contact plus the loop electrode are formed in the deconcentrator, and the loop electrode lead and the stimulating electrode lead penetrate through the slotted holes. The microbend electrode and the electrode contact with holes obviously improve the convenience and the reliability of the artificial cochlea after implantation.
Description
Technical Field
The invention relates to the field of electronic medical treatment, in particular to a micro-bending electrode of an artificial cochlea and a manufacturing method thereof.
Background
At present, two structural forms of artificial cochlea electrode array are used in the world, namely one is a straight electrode array, the other is a pre-bent electrode array and the other is a micro-bent electrode array. The direct electrode is implanted, and then can not hug the inner shaft edge of the cochlea due to the elastic force effect, so that current diffusion and large power consumption are caused, the stimulation effect is influenced, the tissue in the cochlea is easy to squeeze, the cochlea is damaged, the pre-bent array connecting electrode is very inconvenient to implant due to too large bending degree, a supporting wire is used for guiding, a hole is left on the electrode after the supporting wire is pulled out, and the cochlea is damaged when the electrode is not well controlled during implantation.
The contact points adopted by the artificial cochlea electrode array in the world at present are three, one is spherical, the other is annular, and the other is sheet-shaped. The spherical contact electrode array has small exposure area, large power consumption and insufficient stimulation. The annular contact electrode array is a whole circle of stimulation, and the exposed area is large, but the annular contact electrode array can excite nerves except auditory nerves to influence the stimulation purpose. The exposed area of the sheet contact electrode array is between the spherical contact electrode array and the annular contact electrode array, and the whole circle of stimulation is not performed, so that the stimulation effect is good and the power consumption is low. The prior art adopts a sheet-shaped contact array, the contact is a circular arc-shaped sheet, is adhered to the surface of silica gel, has no back-off, is easy to fall off, and has a circular arc bottom, poor directivity during implantation, easy torsion, and can not achieve the aim of activating the direction close to the snail shaft, thereby influencing the stimulation effect.
Disclosure of Invention
The invention aims to solve the technical problem of providing the reverse hook-shaped or U-shaped electrode contact with the lateral hole, which is more firmly combined with the silica gel, has more optimized exposed area, small power consumption and sufficient electric stimulation, and the manufacturing method thereof.
In order to achieve the above object, the technical scheme of the present invention is as follows: the electrode front section comprises a flexible electrode head arranged at the forefront part of the electrode front section, a plurality of electrode contacts arranged at equal intervals on the inner bending side of the microbend electrode, and a first depth mark, a second depth mark and a third depth mark which are sequentially arranged on the outer bending side of the microbend electrode; the middle section of the electrode comprises a first boosting ring, a second boosting ring, an electrode lead fine spiral part and an electrode lead spiral part; the electrode rear section comprises a loop electrode, a loop electrode lead connected with the loop electrode, a stimulating electrode lead connected with an electrode contact and a deconcentrator, wherein slotted holes with the same number as the electrode contact plus the loop electrode are arranged on the deconcentrator for the loop electrode lead and the stimulating electrode lead to pass through; the whole microbend electrode is molded by silica gel injection molding.
Preferably, the electrode middle section further comprises a direction mark and a round angle arranged on the direction mark.
Preferably, the two ends of the loop electrode are provided with a first silica gel ring and a second silica gel ring.
Preferably, the electrode contact is a back hook electrode, a back hook part of the back hook electrode is provided with a first lateral hole and a second lateral hole, and the inner side of the bottom is connected with the stimulating electrode lead wire through a first welding spot.
Preferably, the electrode contact is a U-shaped electrode, the two sides of the U-shape are provided with a third lateral hole and a fourth lateral hole, and the inner side of the bottom is connected with the stimulating electrode lead wire through a second welding spot.
The invention also provides a manufacturing method of the artificial cochlea microbend electrode, which comprises the following steps:
manufacturing an electrode contact;
manufacturing a stimulating electrode lead, welding an electrode contact with the stimulating electrode lead, performing ultrasonic cleaning and performing plasma treatment;
injection molding the welded electrode contact and the stimulating electrode lead by using silica gel, bundling the platinum iridium alloy wires, and spirally forming a slender spiral part of the electrode lead and a spiral part of the electrode lead;
manufacturing a loop electrode;
manufacturing a loop electrode lead, welding a loop electrode and the loop electrode lead, performing ultrasonic cleaning and plasma treatment;
fixing the electrode lead and the electrode lead spiral part in a mold, adding silica gel for injection molding, and performing self-lubricating silica gel coating on the surface;
laser cutting, cleaning and electrical inspection of the exposed surface of the electrode contact;
the manufacturing of the electrode contact comprises the following steps:
annealing and rolling the platinum-iridium alloy blank into a platinum-iridium alloy sheet;
cutting the platinum iridium alloy sheet by laser and then stamping and forming;
the manufacturing of the stimulating electrode lead comprises the following steps:
annealing, cold drawing and straightening the platinum-iridium alloy blank to obtain a platinum-iridium alloy wire;
coating and waved treatment are carried out on the platinum iridium alloy wire;
cutting wires of platinum iridium alloy wires, and removing coatings at two ends;
the manufacturing of the loop electrode comprises the following steps:
annealing, cold drawing, straightening and grinding the platinum-iridium alloy blank into an annular platinum-iridium alloy sheet;
performing laser cutting and deburring;
the manufacturing of the loop electrode lead comprises the following steps:
annealing, cold drawing and straightening the platinum-iridium alloy blank to obtain a platinum-iridium alloy wire;
and coating and cutting wires on the platinum iridium alloy wires, and removing the coatings at the two ends.
Preferably, the electrode contact further comprises laser cutting holes at two sides of the electrode.
The artificial cochlea microbend electrode adopting the technical scheme at least comprises the following beneficial effects:
1. the micro-bent electrode is more convenient in the implantation process by combining the whole shape of the micro-bent electrode with the two boosting rings and the direction marks, has small damage to cochlea and can not cause unnecessary distortion to the whole electrode;
2. the combination of the electrode contact with the lateral hole and the silica gel is firmer, the electrode contact is not easy to fall off, the exposed area of the electrode contact is proper, the implantation reliability and the safety of the artificial cochlea are greatly improved, the implanted electrode is ensured to work normally in a human body for a long time, and the artificial cochlea manufacturing technology is pushed.
Drawings
Fig. 1 is a schematic structural diagram of a microbend electrode for a cochlear implant according to an embodiment of the present invention.
Fig. 2 is a schematic view of an electrode contact (back hook electrode) of an artificial cochlea microbend electrode according to an embodiment of the present invention.
Fig. 3 is a schematic view of an electrode contact (U-shaped electrode) of an artificial cochlea microbend electrode according to another embodiment of the present invention.
Fig. 4 is a flow chart of steps of a method for manufacturing a microbend electrode of an artificial cochlea according to an embodiment of the present invention.
Detailed Description
Referring to fig. 1-3, the artificial cochlea microbend electrode comprises an electrode front section 01, an electrode middle section 02 and an electrode rear section 03 which are sequentially arranged, wherein the electrode front section 01 comprises a flexible electrode head 1 arranged at the forefront part of the electrode front section 01, a plurality of electrode contacts 5 which are arranged at equal intervals on the inner bending side of the microbend electrode, and a first depth mark 2, a second depth mark 3 and a third depth mark 4 which are sequentially arranged on the outer bending side of the microbend electrode; the electrode middle section 02 comprises a first booster ring 7, a second booster ring 8, an electrode lead fine spiral part 11 and an electrode lead spiral part 12; the electrode rear section 03 comprises a loop electrode 13, a loop electrode lead 17 connected with the loop electrode 13, a stimulating electrode lead 18 connected with the electrode contact 5 and a deconcentrator 19, wherein slotted holes 20 the number of which is consistent with that of the electrode contact 5 and the loop electrode 13 are arranged on the deconcentrator 19 for the loop electrode lead 17 and the stimulating electrode lead 18 to pass through; the whole microbend electrode is molded by the silica gel 6. The hardness of the silica gel at the flexible electrode head 1 is 25A-50A, and the hardness of the silica gel 6 is 35A-80A. The wire divider 19 may be rectangular or circular arc shaped and made of silica gel or rubber.
The electrode midsection 02 further comprises a direction marker 9 and a rounded corner 10 arranged on the direction marker 9.
The two ends of the loop electrode 13 are provided with a first silica gel ring 15 and a second silica gel ring 16, which can be used for boosting while playing a role in fixing the loop electrode 13.
The electrode contact 5 is a back hook electrode 28, a first lateral hole 21 and a second lateral hole 22 are arranged at the back hook position, and the inner side of the bottom is connected with the stimulating electrode lead 18 through a first welding point 26.
The electrode contact 5 is a U-shaped electrode 23, the two sides of the U-shape are provided with a third lateral hole 24 and a fourth lateral hole 25, the inner side of the bottom is connected with the stimulating electrode lead 18 through a second welding point 27, and the angle of the U-shape is 25-135 degrees.
The combination of the back hook-shaped electrode 28 or the U-shaped electrode 23 with the lateral hole and the silica gel 6 is firmer, the area of the electrode exposed outside the silica gel 6 is quite proper, and the effect of electric stimulation is also improved.
Corresponding to the electrode, referring to fig. 4, the embodiment of the method of the invention is a manufacturing method of a microbend electrode of an artificial cochlea, comprising the following steps:
s10, manufacturing an electrode contact;
s20, manufacturing a stimulating electrode lead, welding an electrode contact with the stimulating electrode lead, performing ultrasonic cleaning and performing plasma treatment;
s30, injection molding the welded electrode contact and the stimulation electrode lead by using silica gel, bundling the platinum iridium alloy wires, and spirally forming a slender spiral part of the electrode lead and a spiral part of the electrode lead;
s40, manufacturing a loop electrode;
s50, manufacturing a loop electrode lead, welding a loop electrode and the loop electrode lead, ultrasonic cleaning and plasma treatment;
s60, fixing the electrode lead screw part and the electrode lead screw part in a mold, adding silica gel for injection molding, and performing self-lubricating silica gel coating on the surface;
s70, laser cutting, cleaning and electrical inspection are carried out on the exposed surface of the electrode contact;
in S10, the electrode contact is manufactured specifically by the following steps:
annealing and rolling the platinum-iridium alloy blank into a platinum-iridium alloy sheet;
cutting the platinum iridium alloy sheet by laser and then stamping and forming;
in S20, the step of manufacturing the stimulating electrode lead specifically includes the following steps:
annealing, cold drawing and straightening the platinum-iridium alloy blank to obtain a platinum-iridium alloy wire;
coating and waved treatment are carried out on the platinum iridium alloy wire;
cutting wires of platinum iridium alloy wires, and removing coatings at two ends;
in S40, the manufacturing of the loop electrode specifically includes the following steps:
annealing, cold drawing, straightening and grinding the platinum-iridium alloy blank into an annular platinum-iridium alloy sheet;
performing laser cutting and deburring;
in S50, the manufacturing of the loop electrode lead includes the following steps:
annealing, cold drawing and straightening the platinum-iridium alloy blank to obtain a platinum-iridium alloy wire;
and coating and cutting wires on the platinum iridium alloy wires, and removing the coatings at the two ends.
In S10, the electrode contact is manufactured by laser cutting holes at two sides of the electrode.
Finally, it is noted that the above-mentioned preferred embodiments are only intended to illustrate rather than limit the invention, and that, although the invention has been described in detail by means of the above-mentioned preferred embodiments, it will be understood by those skilled in the art that various changes in form and details may be made therein without departing from the scope of the invention as defined by the appended claims.
Claims (5)
1. The artificial cochlea microbend electrode is characterized by comprising an electrode front section, an electrode middle section and an electrode rear section which are sequentially arranged, wherein the electrode front section comprises a flexible electrode head arranged at the forefront part of the electrode front section, a plurality of electrode contacts arranged at equal intervals on the inner bending side of the microbend electrode, and a first depth mark, a second depth mark and a third depth mark which are sequentially arranged on the outer bending side of the microbend electrode; the middle section of the electrode comprises a first boosting ring, a second boosting ring, an electrode lead fine spiral part and an electrode lead spiral part; the electrode rear section comprises a loop electrode, a loop electrode lead connected with the loop electrode, a stimulating electrode lead connected with an electrode contact and a deconcentrator, wherein slotted holes with the same number as the electrode contact plus the loop electrode are arranged on the deconcentrator for the loop electrode lead and the stimulating electrode lead to pass through; the whole microbend electrode is molded by silica gel injection molding;
the middle section of the electrode also comprises a direction mark and a round angle arranged on the direction mark;
the two ends of the loop electrode are provided with a first silica gel ring and a second silica gel ring.
2. The cochlear implant microbend electrode of claim 1, wherein: the electrode contact is a back-hooked electrode, a back-hooked position of the electrode contact is provided with a first lateral hole and a second lateral hole, and the inner side of the bottom is connected with the stimulating electrode lead wire through a first welding spot.
3. The cochlear implant microbend electrode of claim 1, wherein: the electrode contact is a U-shaped electrode, a third lateral hole and a fourth lateral hole are arranged on two sides of the U-shape, and the inner side of the bottom is connected with the stimulating electrode lead wire through a second welding spot.
4. A method for manufacturing a microbend electrode for an artificial cochlea according to any one of claims 1 to 3, wherein: the method comprises the following steps:
manufacturing an electrode contact;
manufacturing a stimulating electrode lead, welding an electrode contact with the stimulating electrode lead, performing ultrasonic cleaning and performing plasma treatment;
injection molding the welded electrode contact and the stimulating electrode lead by using silica gel, bundling the platinum iridium alloy wires, and spirally forming a slender spiral part of the electrode lead and a spiral part of the electrode lead;
manufacturing a loop electrode;
manufacturing a loop electrode lead, welding a loop electrode and the loop electrode lead, performing ultrasonic cleaning and plasma treatment;
fixing the electrode lead and the electrode lead spiral part in a mold, adding silica gel for injection molding, and performing self-lubricating silica gel coating on the surface;
laser cutting, cleaning and electrical inspection of the exposed surface of the electrode contact;
the manufacturing of the electrode contact comprises the following steps:
annealing and rolling the platinum-iridium alloy blank into a platinum-iridium alloy sheet;
cutting the platinum iridium alloy sheet by laser and then stamping and forming;
the manufacturing of the stimulating electrode lead comprises the following steps:
annealing, cold drawing and straightening the platinum-iridium alloy blank to obtain a platinum-iridium alloy wire;
coating and waved treatment are carried out on the platinum iridium alloy wire;
cutting wires of platinum iridium alloy wires, and removing coatings at two ends;
the manufacturing of the loop electrode comprises the following steps:
annealing, cold drawing, straightening and grinding the platinum-iridium alloy blank into an annular platinum-iridium alloy sheet;
performing laser cutting and deburring;
the manufacturing of the loop electrode lead comprises the following steps:
annealing, cold drawing and straightening the platinum-iridium alloy blank to obtain a platinum-iridium alloy wire;
and coating and cutting wires on the platinum iridium alloy wires, and removing the coatings at the two ends.
5. The method for manufacturing the artificial cochlea microbend electrode according to claim 4, wherein the method comprises the following steps of: the electrode contact also comprises laser cutting holes at two sides of the electrode.
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CN108837301B true CN108837301B (en) | 2024-04-09 |
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CN110141782A (en) * | 2019-06-03 | 2019-08-20 | 浙江诺尔康神经电子科技股份有限公司 | Graphene oxide artificial cochlea electrode and preparation method thereof |
CN110448798A (en) * | 2019-07-17 | 2019-11-15 | 浙江诺尔康神经电子科技股份有限公司 | Graphene artificial cochlea electrode and preparation method thereof |
CN110237419A (en) * | 2019-07-23 | 2019-09-17 | 上海华聆人工耳医疗科技有限公司 | Flat half-ring electrodes contact and preparation method thereof |
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CN202184851U (en) * | 2011-08-09 | 2012-04-11 | 杭州诺尔康神经电子科技有限公司 | Slightly-bent artificial cochlea electrode with saddle-shaped contact points |
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CN106031666A (en) * | 2015-03-18 | 2016-10-19 | 浙江诺尔康神经电子科技股份有限公司 | Visual artificial cochlea electrode, system and method for manufacturing same |
CN208756784U (en) * | 2018-05-09 | 2019-04-19 | 浙江诺尔康神经电子科技股份有限公司 | The micro-bend electrode of artificial cochlea |
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2018
- 2018-05-09 CN CN201810435336.9A patent/CN108837301B/en active Active
Patent Citations (6)
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KR20030035783A (en) * | 2002-04-29 | 2003-05-09 | 주식회사 뉴로바이오시스 | Cochlear implant electrode and its fabricating method |
CN202184851U (en) * | 2011-08-09 | 2012-04-11 | 杭州诺尔康神经电子科技有限公司 | Slightly-bent artificial cochlea electrode with saddle-shaped contact points |
CN203609544U (en) * | 2013-11-06 | 2014-05-28 | 复旦大学附属眼耳鼻喉科医院 | Artificial cochlea cranked electrode |
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