CN108831546A - A kind of data processing method, device and non-transient computer readable storage medium - Google Patents
A kind of data processing method, device and non-transient computer readable storage medium Download PDFInfo
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- CN108831546A CN108831546A CN201810652296.3A CN201810652296A CN108831546A CN 108831546 A CN108831546 A CN 108831546A CN 201810652296 A CN201810652296 A CN 201810652296A CN 108831546 A CN108831546 A CN 108831546A
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- dead time
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- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
- G16H40/00—ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices
- G16H40/60—ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices
Abstract
The embodiment of the invention provides a kind of data processing method, device and non-transient computer readable storage mediums.The embodiment of the present invention passes through in the continuous activity section that radioactivity die body is decayed by high activity to low-activity, obtain the counting rate and true coincidence counting rate of the corresponding PET system of multiple activity in the activity section, then, according to the true coincidence counting rate of each activity and with reference to the true coincidence counting rate of activity, obtain the corresponding dead time factor of each activity, later, according to the counting rate of each activity and the dead time factor, the corresponding relationship in the activity section between counting rate and the dead time factor is established.Therefore, technical solution provided in an embodiment of the present invention can solve the problems, such as the dead time factor got in the prior art dependent on low-activity point to a certain extent there are accuracys rate and is lower, improve the accuracy rate of the dead time factor got.
Description
【Technical field】
The present invention relates to technical field of medical equipment more particularly to a kind of data processing methods, device and non-transient calculating
Machine readable storage medium storing program for executing.
【Background technique】
PET (Positron Emission Computed Tomography, positron e mission computed tomography)
Quantitative analysis be built upon and carry out on the basis of every correction correctly, for example, correction for attenuation, scatter correction, random correction
And coincidence correction.Wherein, when to coincidence correction, need to obtain the dead time factor.
In the prior art, the dead time is being obtained because of the period of the day from 11 p.m. to 1 a.m, need first to collect single counting that actual measurement under different activity obtains
Then true coincidence counting rate under rate and different activity by way of carrying out linear fit to low-activity point, obtains the dead time
The factor.
But often noise is larger for low-activity point, deposits to the acquisition of the true coincidence counting rate and counting rate of low-activity point
In large error, this has larger impact for the accuracy of linear fit, causes the result accuracy rate of linear fit lower, thus
The accuracy of the obtained dead time factor is relatively low.
【Summary of the invention】
In view of this, the embodiment of the invention provides a kind of data processing method, device and non-transient computer is readable deposits
Storage media, it is accurate that the dead time factor to solve to get dependent on low-activity point in the prior art to a certain extent exists
The lower problem of rate improves the accuracy rate of the dead time factor got.
In a first aspect, the embodiment of the invention provides a kind of data processing methods, including：
In the continuous activity section that radioactivity die body is decayed by high activity to low-activity, obtain multiple in the activity section
The counting rate and true coincidence counting rate of the corresponding PET system of activity；
The true coincidence counting rate corresponding to each activity in the multiple activity carries out decay correction respectively, obtains
The true coincidence counting rate after the corresponding decay correction of each activity in the multiple activity；
According to the first true coincidence counting rate and the second true coincidence counting rate, each activity pair in the multiple activity is obtained
The dead time factor answered；Wherein, the first true coincidence counting rate is the true symbol after the corresponding decay correction of each activity
Total digit rate, the second true coincidence counting rate are with reference to the true coincidence counting rate after the corresponding decay correction of activity；
According in the multiple activity the corresponding counting rate of each activity and the dead time factor, establish institute
State the corresponding relationship in activity section between counting rate and the dead time factor.
The aspect and any possible implementation manners as described above, it is further provided a kind of implementation, it is described according to
One true coincidence counting rate and the second true coincidence counting rate, obtain each activity corresponding dead time in the multiple activity because
Son, including：
The ratio for obtaining the second true coincidence counting rate Yu the first true coincidence counting rate, to be corresponded to as each activity
The dead time factor.
The aspect and any possible implementation manners as described above, it is further provided a kind of implementation, it is described according to
One true coincidence counting rate and the second true coincidence counting rate, obtain each activity corresponding dead time in the multiple activity because
Son, including：
Third true coincidence counting rate after obtaining the first true coincidence counting rate decay correction corresponding with target activity
Between the first ratio；And second between acquisition the second true coincidence counting rate and the third true coincidence counting rate
Ratio；Wherein, the target activity is an activity in multiple activity in the activity section；
The ratio between second ratio of each activity and first ratio is obtained, it is corresponding to obtain each activity
The dead time factor.
The aspect and any possible implementation manners as described above, it is further provided a kind of implementation, it is described according to institute
The corresponding counting rate of each activity in multiple activity and the dead time factor are stated, is established single in the activity section
Corresponding relationship between counting rate and the dead time factor, including：
It establishes between the corresponding counting rate of each activity in the multiple activity and the dead time factor
Corresponding relationship；
Fitting of a polynomial processing is carried out to the corresponding relationship, obtain in the activity section counting rate and dead time because
The corresponding relationship of son；
According to the corresponding relationship of counting rate and the dead time factor in the activity section, obtain single in the activity section
Corresponding relationship look-up table between counting rate and the dead time factor.
The aspect and any possible implementation manners as described above, it is further provided a kind of implementation, the method is also
Including：
The counting rate of the PET system is acquired in real time；
By the corresponding relationship look-up table in the activity section between counting rate and the dead time factor, obtain with it is described
The corresponding dead time factor of the counting rate of the PET system acquired in real time.
The aspect and any possible implementation manners as described above, it is further provided a kind of implementation, the radioactivity
Die body is homogeneous radiation die body.
Any one technical solution in above-mentioned technical proposal has the advantages that：
In the embodiment of the present invention, in the continuum that is decayed by radioactivity die body by high activity to low-activity, obtaining
The counting rate and true coincidence counting rate that multiple and different activity are obtained in section, by obtain each activity corresponding dead time because
Son finally establishes the corresponding relationship of counting rate and the dead time factor in entire continuous activity section, in the process, area
Not in clicking through the scheme that line process of fitting treatment just obtains the dead time factor only for low-activity in the prior art, the present invention is implemented
Example is handled the data to multiple activity in entire continuous activity section, and it is right to reduce low-activity point acquisition inaccuracy
The influence of the dead time factor, can be improved the accurate of the dead time factor got to a certain extent in entire activity section
Degree solves the problems, such as in the prior art since that there are accuracys rate is lower for the dead time factor that gets dependent on low-activity point.
Second aspect, the embodiment of the invention provides a kind of data processing equipments, including：
First acquisition unit, for obtaining in the continuous activity section that radioactivity die body is decayed by high activity to low-activity
The counting rate and true coincidence counting rate of the corresponding PET system of multiple activity in the activity section；
Unit is corrected, is carried out for the true coincidence counting rate corresponding to each activity in the multiple activity respectively
Decay correction, the true coincidence counting rate after obtaining the corresponding decay correction of each activity；
Second acquisition unit, for obtaining the multiple according to the first true coincidence counting rate and the second true coincidence counting rate
The corresponding dead time factor of each activity in activity；Wherein, the first true coincidence counting rate is the corresponding institute of each activity
True coincidence counting rate after stating decay correction, the second true coincidence counting rate are with reference to true after the corresponding decay correction of activity
Coincidence counting rate；
Establish unit, for according in the multiple activity the corresponding counting rate of each activity and it is described dead when
Between the factor, establish the corresponding relationship in the activity section between counting rate and the dead time factor.
The aspect and any possible implementation manners as described above, it is further provided a kind of implementation, the foundation are single
Member is specifically used for：
It establishes between the corresponding counting rate of each activity in the multiple activity and the dead time factor
Corresponding relationship；
Fitting of a polynomial processing is carried out to the corresponding relationship, obtain in the activity section counting rate and dead time because
The corresponding relationship of son；
According to the corresponding relationship of counting rate and the dead time factor in the activity section, obtain single in the activity section
Corresponding relationship look-up table between counting rate and the dead time factor.
The third aspect, the embodiment of the invention provides a kind of non-transient computer readable storage mediums, which is characterized in that institute
Non-transient computer readable storage medium storage computer instruction is stated, the computer instruction is for executing the computer such as
The described in any item data processing methods of first aspect.
Fourth aspect, the embodiment of the invention provides a kind of data processing equipments, which is characterized in that described device includes place
Manage device and storage medium；The storage medium include computer instruction, the processor for execute the computer instruction with
Realize such as the described in any item data processing methods of first aspect.
Any one technical solution in above-mentioned technical proposal has the advantages that：
In the embodiment of the present invention, in the continuum that is decayed by radioactivity die body by high activity to low-activity, obtaining
The counting rate and true coincidence counting rate that multiple and different activity are obtained in section, by obtain each activity corresponding dead time because
Son finally establishes the corresponding relationship of counting rate and the dead time factor in entire continuous activity section, in the process, area
Not in clicking through the scheme that line process of fitting treatment just obtains the dead time factor only for low-activity in the prior art, the present invention is implemented
Example is handled the data to multiple activity in entire continuous activity section, and it is right to reduce low-activity point acquisition inaccuracy
The influence of the dead time factor, can be improved the accurate of the dead time factor got to a certain extent in entire activity section
Degree solves the problems, such as in the prior art since that there are accuracys rate is lower for the dead time factor that gets dependent on low-activity point.
【Detailed description of the invention】
In order to illustrate the technical solution of the embodiments of the present invention more clearly, below will be to needed in the embodiment attached
Figure is briefly described, it should be apparent that, drawings in the following description are only some embodiments of the invention, for this field
For those of ordinary skill, without creative efforts, it can also be obtained according to these attached drawings other attached drawings.
Fig. 1 is the flow diagram of the embodiment one of data processing method provided by the embodiment of the present invention；
Fig. 2 is the implementation schematic diagram of the embodiment two of data processing method provided by the embodiment of the present invention；
Fig. 3 is a kind of functional block diagram of data processing equipment provided by the embodiment of the present invention；
Fig. 4 is another functional block diagram of data processing equipment provided by the embodiment of the present invention.
【Specific embodiment】
For a better understanding of the technical solution of the present invention, being retouched in detail to the embodiment of the present invention with reference to the accompanying drawing
It states.
It will be appreciated that described embodiments are only a part of the embodiments of the present invention, instead of all the embodiments.Base
Embodiment in the present invention, it is obtained by those of ordinary skill in the art without making creative efforts it is all its
Its embodiment, shall fall within the protection scope of the present invention.
The term used in embodiments of the present invention is only to be not intended to be limiting merely for for the purpose of describing particular embodiments
The present invention.In the embodiment of the present invention and the "an" of singular used in the attached claims, " described " and "the"
It is also intended to including most forms, unless the context clearly indicates other meaning.
It should be appreciated that term "and/or" used herein is only a kind of incidence relation for describing affiliated partner, indicate
There may be three kinds of relationships, for example, A and/or B, can indicate：Individualism A, exists simultaneously A and B, individualism B these three
Situation.In addition, character "/" herein, typicallys represent the relationship that forward-backward correlation object is a kind of "or".
It will be appreciated that though in embodiments of the present invention ratio may be described using term first, second, third, etc.
Deng, but these ratios should not necessarily be limited by these terms.These terms are only used to for ratio being distinguished from each other out.For example, not departing from this
In the case where inventive embodiments range, the first ratio can also be referred to as the second ratio, and similarly, the second ratio can also be claimed
For the first ratio.
Depending on context, word as used in this " if " can be construed to " ... when " or " when ...
When " or " in response to determination " or " in response to detection ".Similarly, depend on context, phrase " if it is determined that " or " if detection
(condition or event of statement) " can be construed to " when determining " or " in response to determination " or " when the detection (condition of statement
Or event) when " or " in response to detection (condition or event of statement) ".
Embodiment one
The embodiment of the present invention provides a kind of data processing method.Referring to FIG. 1, this approach includes the following steps：
S102 is obtained more in activity section in the continuous activity section that radioactivity die body is decayed by high activity to low-activity
The counting rate and true coincidence counting rate of the corresponding PET system of a activity.
S104 carries out decay correction to the corresponding true coincidence counting rate of each activity in the multiple activity respectively, obtains
The true coincidence counting rate after the corresponding decay correction of each activity into multiple activity.
S106 obtains each activity in multiple activity according to the first true coincidence counting rate and the second true coincidence counting rate
The corresponding dead time factor.
Wherein, the first true coincidence counting rate is the true coincidence counting rate after the corresponding decay correction of each activity, and second is true
Coincidence counting rate is with reference to the true coincidence counting rate after the corresponding decay correction of activity.In order to make it easy to understand, the embodiment of the present invention
Related first true coincidence counting rate and the second true coincidence counting rate indicate above-mentioned implication, subsequent to repeat no more.
S108 establishes activity section according to the corresponding counting rate of each activity and the dead time factor in multiple activity
Corresponding relationship between interior counting rate and the dead time factor.
There are the acquisition accuracys rate in dead time mainly for coincidence correction involved in PET scan for the embodiment of the present invention
What this lower scene proposed.Based on this, the embodiment of the present invention is briefly described PET：
The main operational principle of PET system is：By certain substance, usually necessary substance in biological life metabolism, such as：
Glucose, protein, nucleic acid, fatty acid, short-life radionuclide is (such as on label18F,11C etc.), after injecting human body, lead to
The aggregation for the substance in metabolism is crossed, to reflect the situation of vital metabolic activity, to achieve the purpose that diagnosis.It is some short
The substance in service life, releases positive electron in decay process, and a positive electron is in a few tenths of millimeter of advancing to meeting after several millimeters
Bury in oblivion after to an electronics, thus gamma (γ) photon that a pair of of the energy for generating contrary (180 degree) is 511KeV
(based on pair production).This is to γ photon, carries out by super-sensitive captured by camera, and through computer
The correction of scattering and random information.By carrying out identical analysis processing to different positive electrons, we are available in biology
The 3-D image of aggregation situation in vivo.
Based on this, the event that a γ photon is incident on a scintillation crystal can be referred to as " single event ".Same
Detected in time window a pair of of γ photon be incident on a pair of of scintillation crystal event can be referred to as " meeting event ".Meet event
May include：True coincidence event (true coincidence), scattering meet event (scatter coincidence) and at random
Meet event (random coincidence), wherein only true coincidence event contains accurate location information.
In the embodiment of the present invention, counting rate refers to single photon (the i.e. positive electricity received in the unit time in scanning process
The γ photon generated in sub- annihilation event) it counts, true coincidence counting rate refers to the true coincidence counting rate after correcting at random, because
This includes that the true coincidence event number detected in the unit time in scanning process and scattering meet event number.
S102 step is before execution, it is also necessary to guarantee that the radioactivity die body covers system axial field angle (Field of
View, FOV) and positioned at the center of FOV.
In addition, radioactivity die body involved in the embodiment of the present invention is to have radioactive water liquid mould, this is specific real
It now can be depending on the application scenarios for currently needing to do coincidence correction.
In a feasible realization scene, which can be homogeneous radiation liquid mould.For example, uniform water mould
Deng.Wherein, uniformly refer to the state that radioactive substance is evenly distributed in the liquid mould in radioactivity liquid mould.
It is appreciated that homogeneous radiation liquid mould is a kind of preferred realization state, in the actual implementation process, or
The radioactivity liquid mould of heterogeneous state.
Based on conditions above, it is only necessary in the entire continuous acquisition area that radioactivity liquid mould is decayed by high activity to low-activity
Between the multiple and different activity of middle actual measurement counting rate and true coincidence counting rate.
Wherein, the section of high activity and low-activity involved in decay process of the embodiment of the present invention for radioactivity die body
Range is not particularly limited.In actual implementation, high activity and low-activity are in contrast, to be set as needed.For example,
In a concrete implementation scene, in the continuous activity section that can be decayed in radioactivity die body by 10mCi to 1mCi, execute
S102。
It is appreciated that activity, counting rate and true coincidence counting rate correspond, number is equal.And it is multiple and different
Activity is distributed in entire continuous activity section, and is not exclusively located in a certain subinterval in activity section.
In the embodiment of the present invention, it is contemplated that the presence of radioactive decay (Radioactive Decay) is carrying out the dead time
Before the obtaining step of the factor, it is also necessary to true coincidence counting rate decayed (decay) correction.
At this point, S104 step is during specific implementation, can in such a way that calibration factor is multiplied by true coincidence counting rate,
To obtain the true coincidence counting rate after decay correction.Wherein, the decay coefficient of calibration factor and active nucleus and when decay with
It closes.
Based on this, when obtaining the step of the dead time factor in executing S106 step, in order to make it easy to understand, the present invention is implemented
Example provides the implementation of following four S106：
The first：The ratio between the first true coincidence counting rate and the second true coincidence counting rate is obtained, to make
For the dead time factor parameter of the corresponding PET system of each activity；And the inverse of the dead time factor parameter of each activity is obtained, it obtains
To the corresponding dead time factor of each activity.
Wherein, it can according to need default, present invention reality with reference to activity (quality factor, QF, also known as quantitative point)
It applies example and this is not particularly limited.
When the concrete implementation step, following formula can be referred to：
Wherein, 1/SUViIndicate the dead time factor parameter of i-th of activity, SUViIndicate i-th of activity corresponding dead time
The factor, XiTrue coincidence counting rate after indicating the corresponding decay correction of i-th of activity, XQFIt indicates to refer to the corresponding true coincidence of activity
Counting rate.
In specific implementation, due to the dead time factor and dead time factor parameter reciprocal relation each other, obtaining the
The i activity corresponding dead time is because of the period of the day from 11 p.m. to 1 a.m, it is only necessary to obtain the inverse of the dead time factor parameter of i-th of activity.
Second：The ratio between the second true coincidence counting rate and the first true coincidence counting rate is obtained, to make
For the corresponding dead time factor of each activity.It is, obtaining corresponding with each activity with reference to the corresponding true coincidence counting rate of activity
Decay correction after true coincidence counting rate between ratio, obtain the corresponding dead time factor of each activity.
Such as the first implementation, which is omitted the obtaining step to dead time factor parameter, passes through acquisition
The mode of ratio has directly obtained the corresponding dead time factor of each activity, this can be improved entire processing stream to a certain extent
The efficiency of journey.It realizes that process can refer to following formula：
Wherein, SUViIndicate the corresponding dead time factor of i-th of activity, XiAfter indicating the corresponding decay correction of i-th of activity
True coincidence counting rate, XQFIndicate the true coincidence counting rate with reference to activity.
The third：Third true coincidence after obtaining the first true coincidence counting rate decay correction corresponding with target activity
The first ratio between counting rate；And it obtains between the second true coincidence counting rate and the third true coincidence counting rate
The second ratio；Wherein, the target activity is an activity in multiple activity in the activity section；Then, it obtains every
First ratio of a activity and the third ratio of second ratio, obtain the dead time factor parameter of each activity, and
The inverse for obtaining the dead time factor parameter of each activity obtains the corresponding dead time factor of each activity
Wherein, target activity is an activity in the activity surveyed in continuous activity section, this activity can be
Arbitrarily, it is also possible to specified.
In order to make it easy to understand, following formula can be referred to：
Wherein, 1/SUViIndicate the dead time factor parameter of i-th of activity, SUViIndicate i-th of activity corresponding dead time
The factor, B1Indicate the first ratio, B2Indicate the second ratio, XiTrue coincidence after indicating the corresponding decay correction of i-th of activity counts
Rate, XQFIndicate the true coincidence counting rate with reference to activity, XNFor the true coincidence counting rate after the corresponding decay correction of target activity,
In, the value range of i is more than or equal to N.
4th kind：Third true coincidence after obtaining the first true coincidence counting rate decay correction corresponding with target activity
The first ratio between counting rate；And it obtains between the second true coincidence counting rate and the third true coincidence counting rate
The second ratio；Wherein, the target activity is an activity in multiple activity in the activity section；Later, it obtains every
Ratio between second ratio and first ratio of a activity, obtains the corresponding dead time factor of each activity.
Such as the third implementation, which is omitted the obtaining step to dead time factor parameter, passes through acquisition
The mode of ratio has directly obtained the corresponding dead time factor of each activity, this can be improved entire processing stream to a certain extent
The efficiency of journey.It realizes that process can refer to following formula：
Wherein, SUViIndicate the corresponding dead time factor of i-th of activity, B1Indicate the first ratio, B2Indicate the second ratio,
XiTrue coincidence counting rate after indicating the corresponding decay correction of i-th of activity, XQFIndicate the true coincidence counting rate with reference to activity, XN
For the true coincidence counting rate after the corresponding decay correction of target activity, wherein the value range of i is more than or equal to N.
Based on above step, may be implemented to the corresponding dead time factor of activity each in entire continuous activity decay section
Acquisition, can be realized as follows when executing S108 step based on this：
Establish the corresponding counting rate of each activity in above-mentioned multiple activity and the corresponding relationship between the dead time factor；
Fitting of a polynomial processing is carried out to corresponding relationship, it is corresponding with the dead time factor to obtain counting rate in activity section
Relationship；
According to the corresponding relationship of counting rate and the dead time factor in activity section, obtain in activity section counting rate with
Corresponding relationship look-up table between the dead time factor.
During concrete implementation, counting rate and the corresponding relationship of the dead time factor can be shown as in activity section
Corresponding relationship curve.
In order to make it easy to understand, Fig. 2 can be referred to, Fig. 2 .a figure is the mutual pass between counting rate and true coincidence counting rate
It is schematic diagram；Fig. 2 .b figure is the correlation schematic diagram between counting rate and true coincidence counting rate after decay correction；Figure
2.c figure is the correlation schematic diagram between counting rate and dead time factor parameter；Fig. 2 .d figure is counting rate and dead time
Correlation schematic diagram between the factor.
Through the available corresponding relationship curve as shown in Fig. 2 .d of S108 step, it is based on this, corresponding relationship can be generated and look into
Look for table.To, when needing to carry out coincidence correction, with by the corresponding relationship look-up table easily find the dead time because
Son obtains without being subjected to the calculating to activity.
It is, in the method, can also include the following steps：
The counting rate of acquisition PET system in real time；
By the corresponding relationship look-up table in activity section between counting rate and the dead time factor, obtain and acquisition in real time
PET system the corresponding dead time factor of counting rate.
Based on data processing method provided by the embodiment of the present invention, the embodiment of the present invention gives a kind of non-transient calculating
Machine readable storage medium storing program for executing, which is characterized in that non-transient computer readable storage medium stores computer instruction, and computer instruction is used
In the data processing method for making computer execute any implementation as described above.
Any one technical solution in above-mentioned technical proposal has the advantages that：
In the embodiment of the present invention, in the continuum that is decayed by radioactivity die body by high activity to low-activity, obtaining
The counting rate and true coincidence counting rate that multiple and different activity are obtained in section, by obtain each activity corresponding dead time because
Son finally establishes the corresponding relationship of counting rate and the dead time factor in entire continuous activity section, in the process, area
Not in clicking through the scheme that line process of fitting treatment just obtains the dead time factor only for low-activity in the prior art, the present invention is implemented
Example is handled the data to multiple activity in entire continuous activity section, and it is right to reduce low-activity point acquisition inaccuracy
The influence of the dead time factor, can be improved the accurate of the dead time factor got to a certain extent in entire activity section
Degree solves the problems, such as in the prior art since that there are accuracys rate is lower for the dead time factor that gets dependent on low-activity point.
Embodiment two
Data processing method provided by one based on the above embodiment, the embodiment of the present invention, which further provides, realizes above-mentioned side
The Installation practice of each step and method in method embodiment.
On the one hand, referring to FIG. 3, it is a kind of function block of data processing equipment provided by the embodiment of the present invention
Figure.As shown in figure 3, the data processing equipment 300 includes：
First acquisition unit 31, for obtaining in the continuous activity section that radioactivity die body is decayed by high activity to low-activity
Take the counting rate and true coincidence counting rate of the corresponding PET system of multiple activity in the activity section；
Unit 32 is corrected, is declined for the true coincidence counting rate corresponding to each activity in multiple activity respectively
Become correction, the true coincidence counting rate after obtaining the corresponding decay correction of each activity in multiple activity；
Second acquisition unit 33, for obtaining multiple work according to the first true coincidence counting rate and the second true coincidence counting rate
The corresponding dead time factor of each activity in degree；Wherein, the first true coincidence counting rate is that each activity is corresponding described
True coincidence counting rate after decay correction, the second true coincidence counting rate are with reference to the true symbol after the corresponding decay correction of activity
Total digit rate；
Establish unit 34, for according in multiple activity the corresponding counting rate of each activity and the dead time
The factor establishes the corresponding relationship in the activity section between counting rate and the dead time factor.
Wherein, described to establish unit 34, it is specifically used for：
Establish the corresponding relationship between the corresponding counting rate of each activity and the dead time factor；
Fitting of a polynomial processing is carried out to the corresponding relationship, obtain in the activity section counting rate and dead time because
The corresponding relationship of son；
According to the corresponding relationship of counting rate and the dead time factor in the activity section, obtain single in the activity section
Corresponding relationship look-up table between counting rate and the dead time factor.
On the other hand, referring to FIG. 4, it is another function of data processing equipment provided by the embodiment of the present invention for it
It can block diagram.As shown in figure 4, the data processing equipment 400 includes：Processor 41 and storage medium 42；The storage medium packet
Containing computer instruction, the processor is for executing the computer instruction to realize such as the described in any item data of embodiment one
Processing method.
Method shown in embodiment one is able to carry out as each unit in this present embodiment, what the present embodiment was not described in detail
Part can refer to the related description to embodiment one.
Any one technical solution in above-mentioned technical proposal has the advantages that：
In the embodiment of the present invention, in the continuum that is decayed by radioactivity die body by high activity to low-activity, obtaining
The counting rate and true coincidence counting rate that multiple and different activity are obtained in section, by obtain each activity corresponding dead time because
Son finally establishes the corresponding relationship of counting rate and the dead time factor in entire continuous activity section, in the process, area
Not in clicking through the scheme that line process of fitting treatment just obtains the dead time factor only for low-activity in the prior art, the present invention is implemented
Example is handled the data to multiple activity in entire continuous activity section, and it is right to reduce low-activity point acquisition inaccuracy
The influence of the dead time factor, can be improved the accurate of the dead time factor got to a certain extent in entire activity section
Degree solves the problems, such as in the prior art since that there are accuracys rate is lower for the dead time factor that gets dependent on low-activity point.
It is apparent to those skilled in the art that for convenience and simplicity of description, the system of foregoing description,
The specific work process of device and unit, can refer to corresponding processes in the foregoing method embodiment, and details are not described herein.
In several embodiments provided by the present invention, it should be understood that disclosed system, device and method can be with
It realizes by another way.For example, the apparatus embodiments described above are merely exemplary, for example, the unit
It divides, only a kind of logical function partition, there may be another division manner in actual implementation, for example, multiple units or group
Part can be combined or can be integrated into another system, or some features can be ignored or not executed.Another point, it is shown
Or the mutual coupling, direct-coupling or communication connection discussed can be through some interfaces, device or unit it is indirect
Coupling or communication connection can be electrical property, mechanical or other forms.
The unit as illustrated by the separation member may or may not be physically separated, aobvious as unit
The component shown may or may not be physical unit, it can and it is in one place, or may be distributed over multiple
In network unit.It can select some or all of unit therein according to the actual needs to realize the mesh of this embodiment scheme
's.
It, can also be in addition, the functional units in various embodiments of the present invention may be integrated into one processing unit
It is that each unit physically exists alone, can also be integrated in one unit with two or more units.Above-mentioned integrated list
Member both can take the form of hardware realization, can also realize in the form of hardware adds SFU software functional unit.
The above-mentioned integrated unit being realized in the form of SFU software functional unit can store and computer-readable deposit at one
In storage media.Above-mentioned SFU software functional unit is stored in a storage medium, including some instructions are used so that a computer
It is each that device (can be personal computer, server or network equipment etc.) or processor (Processor) execute the present invention
The part steps of embodiment the method.And storage medium above-mentioned includes：USB flash disk, mobile hard disk, read-only memory (Read-
Only Memory, ROM), random access memory (Random Access Memory, RAM), magnetic or disk etc. it is various
It can store the medium of program code.
The foregoing is merely illustrative of the preferred embodiments of the present invention, is not intended to limit the invention, all in essence of the invention
Within mind and principle, any modification, equivalent substitution, improvement and etc. done be should be included within the scope of the present invention.
Claims (10)
1. a kind of data processing method, which is characterized in that the method includes：
In the continuous activity section that radioactivity die body is decayed by high activity to low-activity, multiple activity in the activity section are obtained
The counting rate and true coincidence counting rate of corresponding PET system；
The true coincidence counting rate corresponding to each activity in the multiple activity carries out decay correction respectively, obtains described
The true coincidence counting rate after the corresponding decay correction of each activity in multiple activity；
According to the first true coincidence counting rate and the second true coincidence counting rate, each activity obtained in the multiple activity is corresponding
The dead time factor；Wherein, the first true coincidence counting rate is the true coincidence meter after the corresponding decay correction of each activity
Digit rate, the second true coincidence counting rate are with reference to the true coincidence counting rate after the corresponding decay correction of activity；
According in the multiple activity the corresponding counting rate of each activity and the dead time factor, establish the work
Spend the corresponding relationship in section between counting rate and the dead time factor.
2. the method according to claim 1, wherein described according to the first true coincidence counting rate and the second true coincidence
Counting rate obtains the corresponding dead time factor of each activity in the multiple activity, including：
The ratio between the second true coincidence counting rate and the first true coincidence counting rate is obtained, to correspond to as each activity
The dead time factor.
3. the method according to claim 1, wherein described according to the first true coincidence counting rate and the second true coincidence
Counting rate obtains the corresponding dead time factor of each activity in the multiple activity, including：
Between third true coincidence counting rate after obtaining the first true coincidence counting rate decay correction corresponding with target activity
The first ratio；And the second ratio between acquisition the second true coincidence counting rate and the third true coincidence counting rate；
Wherein, the target activity is an activity in multiple activity in the activity section；
Obtain the ratio between second ratio of each activity and first ratio, obtain each activity it is corresponding dead when
Between the factor.
4. the method according to claim 1, wherein described corresponding according to each activity in the multiple activity
The counting rate and the dead time factor, establish pair in the activity section between counting rate and the dead time factor
It should be related to, including：
It establishes corresponding between the corresponding counting rate of each activity in the multiple activity and the dead time factor
Relationship；
Fitting of a polynomial processing is carried out to the corresponding relationship, obtains counting rate and the dead time factor in the activity section
Corresponding relationship；
According to the corresponding relationship of counting rate and the dead time factor in the activity section, obtain singly counting in the activity section
Corresponding relationship look-up table between rate and the dead time factor.
5. according to the method described in claim 4, it is characterized in that, the method also includes：
The counting rate of the PET system is acquired in real time；
By the corresponding relationship look-up table in the activity section between counting rate and the dead time factor, obtain and described real-time
The corresponding dead time factor of counting rate of the PET system of acquisition.
6. the method according to claim 1, wherein the radioactivity die body is homogeneous radiation die body.
7. a kind of data processing equipment, which is characterized in that described device includes：
First acquisition unit, in the continuous activity section that radioactivity die body is decayed by high activity to low-activity, described in acquisition
The counting rate and true coincidence counting rate of the corresponding PET system of multiple activity in activity section；
Unit is corrected, is decayed for the true coincidence counting rate corresponding to each activity in the multiple activity respectively
Correction, the true coincidence counting rate after obtaining the corresponding decay correction of each activity；
Second acquisition unit, for obtaining the multiple activity according to the first true coincidence counting rate and the second true coincidence counting rate
In the corresponding dead time factor of each activity；Wherein, the first true coincidence counting rate is to decline described in each activity is corresponding
True coincidence counting rate after becoming correction, the second true coincidence counting rate are with reference to the true coincidence after the corresponding decay correction of activity
Counting rate；
Establish unit, for according in the multiple activity the corresponding counting rate of each activity and the dead time because
Son establishes the corresponding relationship in the activity section between counting rate and the dead time factor.
8. device according to claim 7, which is characterized in that it is described to establish unit, it is specifically used for：
It establishes corresponding between the corresponding counting rate of each activity in the multiple activity and the dead time factor
Relationship；
Fitting of a polynomial processing is carried out to the corresponding relationship, obtains counting rate and the dead time factor in the activity section
Corresponding relationship；
According to the corresponding relationship of counting rate and the dead time factor in the activity section, obtain singly counting in the activity section
Corresponding relationship look-up table between rate and the dead time factor.
9. a kind of non-transient computer readable storage medium, which is characterized in that the non-transient computer readable storage medium is deposited
Computer instruction is stored up, the computer instruction is for making the computer execute such as data as claimed in any one of claims 1 to 6
Processing method.
10. a kind of data processing equipment, which is characterized in that described device includes processor and storage medium；The storage medium
Comprising computer instruction, the processor is for executing the computer instruction to realize as described in any one of claim 1 to 6
Data processing method.
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