CN108777955A - Water surface self-diffusion type Labor-saving drug - Google Patents
Water surface self-diffusion type Labor-saving drug Download PDFInfo
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- CN108777955A CN108777955A CN201780016332.0A CN201780016332A CN108777955A CN 108777955 A CN108777955 A CN 108777955A CN 201780016332 A CN201780016332 A CN 201780016332A CN 108777955 A CN108777955 A CN 108777955A
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
- A01N25/02—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests containing liquids as carriers, diluents or solvents
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
- A01N25/02—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests containing liquids as carriers, diluents or solvents
- A01N25/04—Dispersions, emulsions, suspoemulsions, suspension concentrates or gels
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- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Health & Medical Sciences (AREA)
- Toxicology (AREA)
- Pest Control & Pesticides (AREA)
- Plant Pathology (AREA)
- Agronomy & Crop Science (AREA)
- Engineering & Computer Science (AREA)
- Dentistry (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Environmental Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Dispersion Chemistry (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
A kind of water surface self-diffusion type Labor-saving drug (suspended (SS of diffusion being not belonging to previous pharmaceutically dosage form is provided：Spreading Suspension) agent), its be flow, without the movement of flow and water or flow and water movement it is few under conditions of, by the way that the water surface in water environment is added dropwise, it is diffused into the drug of the entire water surface in a short time, and compared with Jumbo rice herbicide and water surface solvent, moreover it is possible to which the drug further realized into water environment spreads the Labor-saving of operation, uniform proliferation.The present invention is in order to solve the above-mentioned technical problem; form the composition of following water surface self-diffusion type Labor-saving drug; i.e. it is the mixture including at least mobility made of the drug ingredient of liquid, grain or powdery and the diffusion ingredient of liquid; the diffusion ingredient dissolving is adsorbed in the drug ingredient or the coating drug ingredient, and the drug ingredient is made to be spread in the water surface；And the mixture of the mobility 20 times of weight, higher than 0 DEG C and less than the water of 40 DEG C of temperature range in it is similarly insoluble, suspended or emulsify.
Description
Technical field
The present invention relates to a kind of water surface self-diffusion type Labor-saving drug, be even if without flow and water movement or water
The movement of stream and water is few, also can be by being injected on the water surface of water environment, and the water surface of self-diffusion to wide scope is whole in a short time
The drug in face can realize that drug spreads the Labor-saving of operation, uniform proliferation.In addition, further relating to the new carrying method of drug.
In addition, the drug type of the water surface self-diffusion type Labor-saving drug of the present invention is named as the suspended (SS of diffusion：Spreading
Suspension)。
Background technology
Drug used in the water environments such as paddy field is divided into more according to form, physical property, drug transporting, spread state etc.
Type (non-patent literature 1 etc.).For example, as it is known that be included as be suspended in water and use emulsifier, Jumbo rice weedings
Agent (Japanese：ジ ャ Application ボ drug), the water surface solvent etc. of finish, and it is adds in solid granula, powder, pesticide substance
Add liquid preparation obtained by emulsifier etc..
As disclosed in patent document 1,2, non-patent literature 2 etc., Jumbo rice is, for example, paddy field with removing with herbicide
The input agent of careless agent, and be the tablet that foams in water soluble package agent and water, only paddy field, active ingredient need to be put into from balk with hand
It is not only suspended in the water surface to be also suspended in water, to make medicine component spread, therefore can realize that pesticide spreads the Labor-saving of operation.
It it is known that the paddy field self-diffusion type granular agrichemical composition as described in Patent Document 3 further improved and its apply
Use method.The invention of patent document 3 is the closed ducted body and surface work by pesticide activity component, bulk specific gravity less than 1
Property the paddy field self-diffusion type granular agrichemical composition that constitutes of agent, input is basined irrigation to be floated on the water surface later in lower paddy field,
Pesticide activity component is spread, left drug does not handle trace on the soil surface in input place, does not have medicative deviation.It must
It must prepare the closed ducted body that bulk specific gravity is less than 1, it is of high cost.
Finish is insoluble in the liquid preparation of water, can directly use or be used after diluting in organic solvent.Because
The possibility that poisoning occurs is high, is used so seldom directly interspersing among crop.
Water surface solvent is by carrying out dropwise addition processing in many places in paddy field, and active ingredient diffuses to entirely together with solvent
The preparation in paddy field；It is finish or emulsifier in preparation classification, by being applied flexibly, it can be achieved that pesticide spreads the laborsaving of operation
Change.
For example, as leaf sheath portion inorganic agent used for ponds, it is proposed that the rice sheath blight disease of patent document 4 prevents and kill off combination
Object.The invention is that rice sheath blight disease prevents and kill off composition, it is characterized in that by the base of pesticide active ingredient and imparting floating on water performance
Agent is constituted, which dissolves or be suspended in base；In addition, the base for assigning floating on water performance is to be selected from shipwreck
Dissolubility or insoluble high boiling solvent and be at normal temperatures liquid the polar solvent with 0.1% or more water solubility
One kind or two or more solvent and surfactant or be at normal temperatures solid paraffin class or the paraffin class and surface-active
The mixture of agent；It is liquid preparation composition, granule composition or tablet composition that this, which prevents and kill off composition, is applied to when by this composition
When paddy field, pesticide activity component floats up to the water surface and is extended together with base, can by being efficiently attached to the leaf sheath portion of rice
Effectively prevent and kill off rice sheath blight disease.
Furthermore disclosed the paddy field input preparations of patent document 5.Specifically, being following paddy field input preparation
With the disinsection method of rice grub：The paddy field is characterized in agricultural water face being enclosed in using finish water-soluble with input preparation
Property container in, the agricultural water face apply finish by the way that slightly water-soluble or water-insoluble active insecticidal components are dissolved in
Proportion forms (claim 1) in 1 nonpolar high boiling solvent below；The disinsection method of the rice grub is characterized in
By the paddy field put into preparation with every 10a be 1~20 and put into preparation total weight reach 100~2000g condition put into
It is administered in the paddy field basined irrigation, water-soluble container dissolves in water, and the finish of content is made to expand on the face of field.
But patent document 4 be directed to solve pesticide active ingredient into water, the technology of the dissolution of the diffusion of soil asks
The invention of the following drug of topic：It is not configured to that pesticide active ingredient is made to absorb from the root or leaves and stems of rice, but in order to coordinate
The ecology of rice sheath blight disease makes pesticide active ingredient efficiently be attached to the leaf sheath portion (0006) contacted with the water surface, only makes it in water
The drug being unfolded on face.In addition, because surfactant of the addition with emulsification, drug ingredient is in water in patent document 5
In dimensionally spread, so compared with the water surface self-diffusion type Labor-saving drug of the present invention, drug fed distance declines, therefore must
The application in multiprocessing place must be carried out with high concentration, volume, therefore uneconomical.
Existing technical literature
Patent document
Patent document 1：Japanese Patent Laid-Open 06-65010 bulletins
Patent document 2：Japanese Patent Laid-Open 2002-3301 bulletins
Patent document 3：Japanese Patent Laid-Open 2001-163705 bulletins
Patent document 4：Japanese Patent Laid-Open 06-336402 bulletins
Patent document 5：Japanese Patent Laid-Open 05-339103 bulletins
Non-patent literature
Non-patent literature 1：http://www.nichino.co.jp/products/basic/basic06.html
" dosage form based on pesticide classification "
Non-patent literature 2：http://www.japr.or.jp/gijyutu/005.html
" Jumbo rice herbicide "
Invention content
The technical problems to be solved by the invention
Even Jumbo rice herbicides, it is also necessary to so that larger floatability particle (0.5-10mm) is spread in the water surface,
And be using the mechanism of suspended three-dimensional diffusion in water in water, so the arrival distance of drug ingredient is there are the limit,
100m2A place is put into the range of left and right, still more to more than 250m2Large area to be diffused be impossible, if
It is paddy field, it is also necessary on one side being put into while ridge is walked up and down, although in order to realize that pesticide spreads the Labor-saving of operation,
If old man, walk up and down in ridge also by no means easy.In addition, Jumbo rice is that drug ingredient will be made to be attached to herbicide
The substance of floatability particle (0.5-10mm) is filled in the herbicide in water-soluble film bag, if drug ingredient is released into water
Face, then easy to be affected by wind, drug ingredient is scraped sometimes causes to be unevenly distributed together, causes drug ineffective problem and medicine
Evil problem.
On the other hand, even water surface solvent, and in 100m2A place is put into the range of left and right, still more
To more than 250m2Large area to be diffused be impossible, if it is paddy field, it is necessary on one side. while ridge is walked up and down
Input.In addition, the practical example other than the drug ingredient dissolved the oil as base material is not present.
In addition, as shown in Fig. 1 (A), have " in water " emulsification or suspended property previous water surface solvent 2 (or
Oil-type water surface solvent) it is not the water surface solvent for diffusing to range wide enough.That is, water surface solvent 2 is dripping
Carry out three-dimensional diffusion in water simultaneously, the diffusion velocity of drug ingredient and development distance square inversely proportionally reduce.In general,
For the water surface solvent (water surface expansion comprising solid constituent and spread unknown) of the liquid in paddy field, expect it in water
Three-dimensional is uniformly distributed, and assigns its emulsibility and suspended, in order to assign emulsibility and suspended, is added with emulsifier.This
Outside, directly it is that solid constituent is made to be suspended in the preparation in water to the suspending agent of paddy field dispersal type, so having certainly in water
Suspended (http://www.greenjapan.co.jp/noyak_zaikei.htm).
In the past, the pharmaceutical composition of most pesticide etc. was to be diluted with water or comprising water or equably dissolve, emulsify, outstanding
The turbid mode in Soil surface water uses, it is believed that exactly such mode can realize uniform drug conveying.Therefore, especially in liquid
In the pharmaceutical composition of state, till now, directly spreads or carried out with organic solvent dilute there is no water is not related to completely
Drug other than the finish released, and the preparation of water-soluble, emulsibility and suspended is not assigned (not comprising to emulsification and suspended having
The preparation of the surfactant of sufficient property quality and quantity).In particular, to the paddy field, medicine that puts into aquaculture pond, other waters surface
In the range of object, up to the present, still without the drug without water-soluble, emulsibility and suspended.
Then, the object of the present invention is to provide a kind of water surface self-diffusion type Labor-saving drugs 1 using as not by previous medicine
The suspended liquor of diffusion of the novel drugs type of object type classification, is the movement even if movement or flow and water without flow and water
It is few, can also be as shown in Fig. 1 (B), by being added dropwise, being injected on the water surface 3 of water environment, self-diffusion is whole to the water surface in a short time
The drug in face can further realize distribution of the drug in water environment compared with Jumbo rice herbicide and water surface solvent
The Labor-saving of operation, uniform proliferation.The suspended liquor of the diffusion is also that can use the practical of drug ingredient in a solid state
Pharmaceutically dosage form, the drug ingredient be that could not be used for the solid of water surface solvent in the past and be slightly solubility and insoluble drug at
Point.In addition, for the chemicals treatment in the environment of the intervention water surface, it is proposed that utilize the Labor-saving of two benches diffusion mechanism gradually
Method.
Technical scheme applied to solve the technical problem
In the present invention, by making the drug for not having dissolubility, emulsibility and suspended equally in water be spread in the water surface,
Using being considered handling one local drug input of drug trend of purchasing in the presence of limitation in previous elementary introduction to drug delivery technique, reach
Drug ingredient has been arrived to 100m2To more than 250m2The paddy field of area etc. in automatic conveying.Thereby, it can be dramatically improved
Drug spreads the Labor-saving of operation into water environment.
That is, instead of the three-dimensional diffusion into water in previous one stage of drug, the laborsaving chemical drug of water surface self-diffusion type of the invention
In object, pass through the diffusion mechanism structure of the vertical direction of the diffusion mechanism and (2) second stage of the horizontal direction by (1) first stage
At two benches diffusion mechanism gradually combination, realize drug it is efficient over long distances uniformly conveying；Above-mentioned (1) first stage
Horizontal direction diffusion mechanism be using the gravity of water surface self-diffusion type Labor-saving drug and using to the adsorption of the water surface,
The equally distributed diffusion mechanism for the drug ingredient for being difficult to rely on the distance that processing place is put into from drug is realized in a short time；
The diffusion mechanism of the vertical direction of above-mentioned (2) second stage is to be later than the diffusion of horizontal direction, by drug ingredient from the water surface to water
Middle slow mechanism dissolved is simultaneously spread, and the diffusion mechanism of water environment bottom is reached from the water surface.
Here, for using water surface self-diffusion type Labor-saving drug gravity and using to the adsorption of the water surface,
The diffusion of (first stage) horizontal direction of the drug in water environment carries out following explanation.
1) first, to being said using gravity but not using expansion of the drug of the adsorption to the water surface in water environment
It is bright.In the water surface when being put to the water surface to the water-insoluble fluid composition (hereinafter referred to as " fluid composition ") of water floatability
On expansion illustrate, the fluid composition do not include be suitable on the water surface be unfolded and spread degree of polarity pole
Property group (hereinafter referred to as " polar group appropriate ").After just putting into, the liquid group (Japanese of fluid composition：Block) due to
The liquid of fluid composition caused by dead weight caused by gravity is rolled into a ball by the active force on compression direction, starts to expand on the water surface
It dissipates.At this point, the active force in direction that the expansion power of the fluid composition is concentrated with the liquid group as the fluid composition, that is, glue
Degree and surface tension confrontation.Then, the thickness of the layer of the fluid composition is thinning.Then, when the liquid compositions being unfolded in the water surface
When the thickness of object is further thinning, the compression conducted oneself with dignity caused by the gravity fought with the viscosity of fluid composition and the work that power is unfolded
With becoming smaller, development rate declines.
When the thickness of expansion film of the fluid composition on the water surface is further thinning, because not including polar group appropriate
Group, so fluid composition is inadequate to the adsorption capacity of the water surface, the water surface expansion of fluid composition caused by gravity cannot fight liquid
The expansion of the surface tension of state composition, the fluid composition on the water surface stops.The state is non-liquid water-soluble composition
Liquid group swims in the state on the water surface.
2) then, to being said using gravity and to the diffusion in water environment of the present invention of the adsorption of the water surface
It is bright.The water surface self-diffusion type Labor-saving drug of the present invention is blended with water floatability, the polarity with the diffusion being suitable on the water surface
The diffusion ingredient of group.Diffusion when being put into the water surface for the water surface self-diffusion type Labor-saving drug on the water surface carries out
Explanation.After just putting into, the liquid of water surface self-diffusion type Labor-saving drug rolls into a ball the liquid due to fluid composition caused by dead weight
Group starts to spread by the active force on compression direction on the water surface.At this point, the diffusion of the water surface self-diffusion type Labor-saving drug
The active force in direction that power is concentrated with the liquid group as the fluid composition, i.e. viscosity and surface tension are fought.Then, the water
The thickness of the layer of face self-diffusion type Labor-saving drug is thinning.Then, when the water surface self-diffusion type Labor-saving drug spread in the water surface
Thickness it is further thinning when, the compression conducted oneself with dignity caused by the gravity fought with the viscosity of water surface self-diffusion type Labor-saving drug and
The effect of expansion power becomes smaller, and diffusion velocity declines.
But in the water surface self-diffusion type Labor-saving drug for being blended with the diffusion ingredient comprising polar group appropriate
In, water surface self-diffusion type Labor-saving drug is attracted on the water surface, forms the diffusion barrier of thermodynamically stable film-form.As a result,
Even if water surface self-diffusion type Labor-saving drug saves if the thickness of the diffusion barrier on the water surface is further thinning with water surface self-diffusion type
The surface tension of power chemical drug object continues to fight, and wide range is continued to diffuse on the water surface.
3) finally, to not being that the example of generation three-dimensional diffusion of the purpose of the present invention illustrates, that is, hardly utilize weight
Power, because of the strong absorption to water, drug ingredient is solubilized in water by micro emulsion, emulsification, suspended, not only in the water surface,
Boundary unmixing with water is also formd in water, to which three-dimensional diffusion occur.Certainly, including polarity very strong substance
Composition has dissolubility, emulsibility, suspended, causes to the three-dimensional diffusion carried out in water.Therefore, the composition cannot be as
The present invention makes full use of gravitational effects and only acts on the adsorption of the water surface like that, expanding to very wide range on the water surface
Scattered diffusivity is low, wherein the gravitational effects are separated into two layers in water surface boundary drug ingredient and diffusion ingredient,
The gravitational effects caused by the weight of the substance on the upper layer in two layers as a result,.
Also include granular or powdered solid of the proportion 1 or more in the composition comprising the very strong substance of polarity
In the case of drug ingredient, after solid medicine ingredient becomes suspended state in water, start to settle in water immediately in the position.
It is thus impossible to achieve the object of the present invention, i.e., can not achieve to the conveying of the efficient drug of wide scope.On the other hand, it is spreading
In the case of the degree of polarity of action component is appropriate, even proportion in 1 or more granular or powdered solid medicine ingredient,
Can confrontation being settled caused by density in water, drug ingredient is supported on water surface boundary by diffusion ingredient, passes through this
The two benches diffusion mechanism gradually of invention makes drug ingredient diffuse to wide scope.In this way, the water surface self-diffusion type of the present invention saves
The automatic conveying of the drug ingredient of long range can be realized if even if power chemical drug object is in the water environment of not flow, but and there is no harm in
Hinder application in the state of having flow.
In the sense that, water surface self-diffusion type Labor-saving drug utilization of the invention is by the horizontal proliferation of first stage
The two benches diffusion mechanism gradually combined with the diffusion into water in the vertical direction of its subsequent second stage, wherein on
The horizontal proliferation for stating the first stage is the gravitational effects by staying in the dead weight caused by water surface upper layer and the surface suction to the water surface
Horizontal proliferation caused by attached.
In order to solve the above-mentioned technical problem, more specifically, composition of the invention is as follows.
(1)
A kind of water surface self-diffusion type Labor-saving drug, it is the drug ingredient and liquid including at least liquid, grain or powdery
Diffusion ingredient made of mobility mixture, diffusion ingredient dissolving or be adsorbed in the drug ingredient,
Or the coating drug ingredient, so that the drug ingredient is not settled and is supported on the water surface, the drug ingredient is made to exist
The water surface diffusion；
And it is the mixture of the mobility in 20 times of weight, temperature range higher than 0 DEG C and less than 40 DEG C water
After middle oscillation mixing, the two-phase with the water is separated within 3 minutes, similarly insoluble, suspended or emulsification drug；
Has the two benches diffusion machine gradually being made of the diffusion mechanism of the diffusion mechanism of horizontal direction and vertical direction
Reason,
The diffusion mechanism of the horizontal direction, which is that one from the drug in water environment is local, intensively to be lighted, profit
The adsorption of the water surface is acted on gravity and the diffusion ingredient, makes the drug ingredient in the uniform distribution of the water surface；
The diffusion mechanism of the vertical direction is that the drug ingredient is made slow mechanism dissolved and to be spread into water from the water surface,
It is later than the diffusion of the horizontal direction, the water environment bottom is reached from the water surface.
(2)
(1) the density ratio water of the drug ingredient of the water surface self-diffusion type Labor-saving drug described in is big.
(3)
(1) water surface self-diffusion type Labor-saving drug described in be the liquid for making drug ingredient diffusion diffusion at
Divide and is formed by comprising a kind or more selected from the compound in the molecule with ester bond, amido bond, ehter bond, carboxyl, hydroxyl.
(4)
(1) water surface self-diffusion type Labor-saving drug described in also includes straight-chain hydrocarbons as viscosity modifier.
(5)
(1) diffusion of the liquid for making the drug ingredient diffusion of water surface self-diffusion type Labor-saving drug described at
Divide is selected from the one kind or two or more of soybean oil, Castor oil, linseed oil, 2-Ethylhexyl Alcohol, oleic acid and methyl oleate.
(6)
(1) grain of water surface self-diffusion type Labor-saving drug or the drug ingredient of particle described in are display 1mm or less
Average grain diameter solids, and be suspended in the diffusion ingredient.
(7)
A kind of water surface self-diffusion type Labor-saving drug, the diffusion is by the laborsaving chemical drug of water surface self-diffusion type described in (1)
Object is dropped in a place, and under conditions of there is no flow, and area is more than 250m2Diffusion.
(8)
Water surface self-diffusion type Labor-saving drug as described in (1), excludes from the water surface self-diffusion type Labor-saving drug
Include the water surface self-diffusion type Labor-saving drug of the emulsibility surfactant of 1~20 weight %.
(9)
Water surface self-diffusion type Labor-saving drug as described in (1), excludes from the water surface self-diffusion type Labor-saving drug
Include the water surface self-diffusion type Labor-saving drug of the surfactant of 1~20 weight %.
(10)
A kind of Labor-saving drug distributing method is by the water surface self-diffusion type Labor-saving infusion of medicine described in (1) to water environment
The water surface makes it uniformly be spread in the water surface, and the drug ingredient is made to be uniformly spread in water environment.
(11)
(10) water environment of the Labor-saving drug distributing method described in is paddy field.
(12)
A kind of Labor-saving drug distributing method is the two benches diffusion for making water surface self-diffusion type Labor-saving drug pass through gradually
Drug ingredient is diffused into water environment by mechanism；
The water surface self-diffusion type Labor-saving drug is flowed made of the diffusion ingredient comprising drug ingredient and liquid
The diffusion ingredient of the mixture of dynamic property, the liquid dissolves or is adsorbed in the drug ingredient or the coating drug
Ingredient makes the drug ingredient not settle and be supported on the water surface, and the drug ingredient is made to be spread on the water surface；
The two benches diffusion mechanism gradually is：First by the water surface self-diffusion type Labor-saving infusion of medicine to water ring
The water surface in border, making it, diffusion profile then makes the water surface self-diffusion type Labor-saving drug to be later than in the horizontal direction in the water surface
The mode of diffusion profile and reaches the water ring along vertical direction slow mechanism dissolved from the water surface to water in the horizontal direction
The bottom in border.
(13)
Labor-saving drug distributing method as described in (12), under the water environment there is no flow, by by the water surface
Self-diffusion type Labor-saving drug is dropped in a place, and the drug ingredient is diffused into the water surface area more than the water environment
100m2Range.
(14)
Labor-saving drug distributing method as described in (12), under the water environment there is no flow, by by the water surface
Self-diffusion type Labor-saving drug is dropped in a place, and the drug ingredient is diffused into the water surface area more than the water environment
250m2Range.
Here, as " water environment ", the aquaculture pond of paddy field, lotus field, horseradish field, fish etc., facility can be illustrated or need to drive away
The general pond etc. of wriggler or other pests.Medicine manually or automatically further preferably suitable for hydroponic culture and plant factor
Object processing.
" drug " include the fertilizer acted to aquatic plant, biology, water environment or desinsection, sterilization, various for pre-
The drug ingredient of anti-pesticide etc., and the diffusion ingredient that makes drug ingredient be spread in the water surface.
As long as drug ingredient does not interfere the drug ingredient of the two benches diffusion gradually of the present invention that can use, but monomer
I.e. dissolubility not instead of in water, it is dissolving on a small quantity or pass through at any time and in the water that dissolves on a small quantity slightly solubility (at 20 DEG C
In water, dissolving is less than 10g/L), it is the functional components for playing interacting goals by dissolving, is that the big solid-state of density ratio water is micro-
Crushed material can generally also have the property settled in water.
Certainly, the small ingredient of density ratio water also can be used as object.For example, in the case of being dispersed on the water surface with monomer, coagulate
Collection is bulk, show difficult suspended, insoluble property drug ingredient in the case of, diffusion function of the invention especially has
It plays a role to effect, can reliably show diffusion, dissolving, interacting goals.Can prevent with drug ingredient agglutination, concentrate or
The poisoning caused by density unevenness of non-diffusing.
As drug ingredient, for example, as " fungicide ", simeconazoles, metalaxyl, flutolanil, isotianil, alkene can be illustrated
Propyl benzene thiazole, pyroquilon, tricyclazole, valida etc. can illustrate ethiprole, silafluofene, second cyanogen chrysanthemum as " insecticide "
Ester, ethofenprox, dinotefuran, clothianidin, Nitenpyram, metacetaldehyde, cartap, BPMC, MEP, imidacloprid, Diacloden, more sterilizations
Element, pymetrozine, chlorantraniliprole etc. can illustrate pyrazoxyfen, pyrazolate, benzofenap, sulphonyl grass pyrazoles, benzo as " herbicide "
Bicyclic ketone, mesotrione, benzophenone azoles, Machete, pretilachlor, mefenacet, dimethametryn, daimuron, azimsulfuron, azoles
Pyrazosulfuron, cypromisulfuron, pyrazosulfuron, bensulfuron-methyl, cyclic ethers pyrazosulfuron (metazosulfuron), MCPB, MCP,
2.4-PA, pyriftalid remove barnyard grass peace, cyhalofop-butyl, flumetsulam (pyrimisulfan) etc..It is not limited in agriculture chemical registration institute
The drug having is considered to have active most materials and fertilizer etc. in a variety of applications where, can also be suitable as drug ingedient.
In addition, about pesticide field, there are the pesticides described in following URL.
1) benchmark is instructed in 27 years mountain passes of Heisei county crop disease pest, weed control
http://www.nrs.pref.yamaguchi.lg.jp/hp_open/a1720160/00000008/0 02%
20mokuji.htm
2) (4) 2 rice casees of V-1- application ridging processing http://www.nrs.pref.yamaguchi.lg.jp/
Hp_open/a1720160/00000008/302 crop 1-3 casees application ridging processing .pdf
3) (4) 3 rice on honda fungicide of V-1-
http:03 crops of //www.nrs.pref.yamaguchi.lg.jp/hp_open/a1720160/00000008/3
1-7 Hondas drug .pdf
4) active ingredient of V-7- (5) rice herbicide and action characteristic guide look
http://www.nrs.pref.yamaguchi.lg.jp/hp_open/a1720160/00000008/1 75%
EF%BC%98%EF%BC%88%EF%BC%95%EF%BC%89%E6%B0%B4%E7%94%B0%E9 %
99%A4%E8%8D%89%E5%89%A4%E3%81%AE%E6%9C%89%E5%8A%B9%E6%88 %
90%E5%88%86%E3%81%A8%E4%BD%9C%E7%94%A8%E7%89%B9%E6%80%A7 %
E4%B8%80%E8%A6%A7.pdf
5) the pesticide guide look (rice herbicide) listed in weed control guide
http://www.agri.hro.or.jp/boujosho//boujo-guide/h26boujo-guide/
h26boujoguide-pdf/42002_ine-syoki_h26.pdf
6) agriculture chemical registration information download-agricultural aquatic products consumption safety technique center
http://www.acis.famic.go.jp/ddata/index.htm
Diffusion ingredient is the substance for having surface active function, but is not to have the emulsification of oil-soluble ingredients in water
The substance of effect, but the substance with water surface diffusion.For example, the surfactant of the range of HLB1~4 can be illustrated, divided
Powder etc..In addition, be oil-soluble by the grease type of representative of soybean oil, but the content, property, work for passing through hydrophilic radical
With in floating on water or in water surface progress self-diffusion (two dimension).
In patent document 4, as surfactant, illustrate " SURFYNOL ".Moreover, volume makes in all of the embodiments illustrated
With " SURFYNOL ".
Here, SURFYNOL is as recorded in the 0014th section of Japanese Patent Laid 2011-512418 bulletins
" SURFYNOL104PG-50 (trade mark) is added to before drug imports aqueous phase in internal oil phase.The product of gained
It is characterized in that the very small grain size with about 230nm, the experimental result can reappear.The Size Distribution may be by being used to prevent
Caused by the ability of the SURFYNOL104PG-50 (trade mark) of agglutination, it is uniform and very it is narrow (polydispersity index (PDI)~
0.1)." as, it is imported in water phase from by drug (oil phase), is formed as the content of small grain size it is found that SURFYNOL is
By the emulsibility surfactant of grease emulsifying Cheng Shuizhong oil types.
In the present invention, because being that drug ingredient is made to be spread with two benches diffusion mechanism gradually, (containing volume
Emulsibility surfactant (being 1~20 parts by weight relative to 100 parts by weight of drug) is used as diffusion ingredient) in the case of,
It is possible that cannot achieve the purpose of invention.
That is, in the case where adding the emulsibility surfactant as the SURFYNOL of patent document 4, lived with surface
Property agent additive amount (the 0009th section " surface (SURFYNOL 104, gas products company (エ ア-プ ロ ダ クツ societies) system)
Activating agent can suitably select to make from 100 parts by weight of composition are prevented and kill off relative to rice sheath blight disease for the range of 1~20 parts by weight
With.") will be unable to realize the present invention drug ingredient wide scope diffusion (two benches diffusion mechanism gradually), according to above
Content, it may also be said to which the present invention is different with patent document 4.
Patent document 4 is spread by the water surface, and drug is made to be attached to the technology of the stem of rice, and the present invention is literary with patent
It is entirely different in the purpose, effect of invention to offer 4.More specifically, in patent document 4, as recorded in the 0006th section of specification
" unthink from the thinking of previous the method for control, be not make pesticide active ingredient from the root or leaves and stems of rice absorb, and
It is to coordinate the ecology of rice sheath blight disease that pesticide active ingredient is made efficiently to be attached to the leaf sheath portion contacted with the water surface, and make its absorption
To rice body " like that, only consider the expansion in the water surface, and be not intended into water, the diffusion in soil, deterrent is avoided into water
Diffusion.
On the other hand, the present invention, which has, " makes drug ingredient be spread in a manner of slow mechanism dissolved into water by from the water surface, evening
In the diffusion of the horizontal direction, the diffusion mechanism for the vertical direction for reaching from the water surface water environment bottom ".
That is, the technology of patent document 4 as recorded in it " be not make pesticide active ingredient from the root or leaves and stems of rice inhale
Receive " as, it is not intended into water, the diffusion in soil, but avoids the diffusion into water, in soil；It understands in this hair
On the point of bright " reaching water environment bottom ", patent document 4 and the present invention 1 are different in fundamentally technological thought, and patent document 4 does not have
There is the motivation for reaching the present invention, but has the prior art of inhibition to the creation of the present invention.
Incidentally, it will be clear that patent document 4 by volume includes for " local application " and being attached to
" surfactant " of " leaf sheath portion " is not intended to also be not carried out due to " concentration in the water surface of drug ingredient reduces "
The expansion of the water surface of wide scope is also not intended to that drug is made to spread into water, so touching the art technology of patent document 4
Personnel will not be expected the diffusion into water, in soil, the wide scope expansion of the present invention from patent document 4 anyway, and
" Labor-saving that drug is spread ".
Due to above difference, compared with based on the diffusion (three-dimensional) into water caused by emulsification in water, suspended system,
Invention efficiently, equably can also spread (distribution) to wide scope with a small amount of drug.Emulsification, the expansion of suspended system in based on water
It dissipates in (three-dimensional), forms the diffusion to water volume range, need the distribution ingredient of volume, and if from the medicine of three-dimensional diffusion
Object put into place distance farther out, then the drug concentration spread drastically declines (in principle, the drug concentration with put into distance location
It is square inversely proportional).On the other hand, in the diffusion of the water surface, the gravity and diffusion that are generated because being separated into two layers
Ingredient and drug ingredient play a role to the absorption of the water surface, thus the drug concentration on the water surface promptly, with independent of hauling oneself willingly into
Entering the mode of the distance in place becomes uniform.
In addition, the water surface is promptly completely covered by the water surface self-diffusion type Labor-saving drug of the present invention, drug constitutes molecule
Pressure is unfolded in the water surface by using the diffusion barrier of the water surface, the structure mutually squeezed is formed on the water surface, to stabilize.Cause
This, can inhibit to scrape the non-uniform drug distribution of generation due to blowing for wind etc., can realize uniform drug distribution situation.
For example, " grease type for deriving from animals and plants " as the ester compounds of aliphatic acid and glycerine, exists as drug is made
The diffusion ingredient spread on the water surface of wide scope has hydrophily appropriate and hydrophobic balance, expands to being not dissolved in
In the case that the solid medicine ingredient of scattered action component has carried out crushing and decentralized processing, the same of stable suspension can prepared
When, which can also have simultaneously does not emulsify water and suspended property.It is single using soybean oil as the fluid oil lipid of representative
The suitable material that can solely have the quality that simultaneously.
Here, " aliphatic acid " refers to " monocarboxylic acid of long chain hydrocarbons.In general, a aliphatic acid of carbon number 2-4 is known as short chain fat
Carbon number 5-12 aliphatic acid is known as medium chain fatty acid by fat acid (lower fatty acid), and the aliphatic acid of carbon number 12 or more is claimed
For long chain fatty acids (higher fatty acids).There are a variety of sayings for the division of carbon number.Aliphatic acid is indicated by general formula CnHmCOOH.Fat
Acid is esterified with glycerine and constitutes grease."
(https://ja.wikipedia.org/wiki/%E8%84%82%E8%82%AA%E9%85%B8)
The typically glycerine of the aliphatic acid of 3 molecules and 1 molecule is esterified to constitute grease, but there is also the hydroxyls of glycerine
It is not remaining there is a situation where esterification.
As diffusion ingredient, such as hydroxyl of the intramolecular with ester bond, amido bond, ehter bond, carboxyl, alcohol can be used
The grease type of part, the plasticizer class of synthetic resin addition and other chemical substances of equal low poles.
In addition, in the case where drug ingredient is insoluble in liquid parts comprising diffusion ingredient, need to make drug at
Be allocated as particle it is suspended in the formulation, and as the present invention attempt as, in order to which the preparation not being suspended in water is made, need
Using polar intensity substance appropriate as diffusion ingredient.As such diffusion ingredient, can be suitably used big
Soya-bean oil, rapeseed oil, cottonseed oil, corn oil, linseed oil, sesame oil, grape seed oil, olive oil, canola oil, rice bran oil, tung oil, castor
Flaxseed oil, coconut oil, safflower seed oil, sunflower oil, peanut oil or their substance for implementing the chemical modifications such as epoxidation,
Or oleic acid, linoleic acid, leukotrienes etc. or their methyl ester, glyceride etc..In addition, it is possible to use dioctyl phthalate,
The plasticizer class conduct such as diisononyl phthalate, diisooctyl phthalate, dioctyl adipate, tricresyl phosphate
Diffusion ingredient.In addition, it is possible to use the alcohols of 2-Ethylhexyl Alcohol, octanol, hexanol etc. is as diffusion ingredient.In addition,
Except above-mentioned in addition to these, as long as the liquid for not mixing with water and being spread on the water surface, so that it may for use as diffusion ingredient.
In addition, as recorded in Japanese Patent Laid-Open 6-336402 (patent document 4), it sometimes can be by adding on a small quantity
Water-soluble polar solvent, to improve diffusivity of the drug ingredient on the water surface.But if to be more than damage water surface self-diffusion
The amount of the degree of the key property of type Labor-saving drug itself, i.e., insoluble, non-emulsified property in water and non-suspended is added,
Then water surface self-diffusion declines, and damages the long distance delivery of drug ingredient.With the combination of drug ingredient and diffusion ingredient
It matches, determines the amount of being properly added of above-mentioned polar solvent.
The condition of " mixture of mobility is similarly insoluble, suspended in water or emulsifies " is, by diffusion ingredient
Or water surface self-diffusion type Labor-saving drug 0.25mL is added in 5mL water, with 5Hz vibrate 5 minutes, be then allowed to stand 3 minutes, water and
The mixture of mobility is separated into two-phase.
In addition to drug ingredient and diffusion ingredient, it can be wrapped in the water surface self-diffusion type Labor-saving drug of the present invention
Containing straight-chain hydrocarbons such as dodecanes.Straight-chain hydrocarbons is not diffusion ingredient, is worked as viscosity modifier.In order to make drug ingredient exist
The water surface is spread rapidly, can be adjusted to low water by water surface self-diffusion type Labor-saving drug, especially by the viscosity of diffusion ingredient
It is flat.The compatibility of the long-chain fat acid moieties of the straight-chain hydrocarbons such as dodecane and grease type etc. is high, so by being suitably added to expansion
It dissipates in action component, is not damaging the suspended stability of water surface diffusivity, drug ingredient in the formulation and non-dissolving in water
Property and non-suspended under the premise of, the viscosity of water surface self-diffusion type Labor-saving drug can be reduced, have improve water surface self-diffusion type
The effect of the water surface diffusion velocity of Labor-saving drug.
As viscosity modifier, in the case of saturated hydrocarbons, carbon number is high in the volatility of 8 hydrocarbon below, and property on fire is high.This
Outside, carbon number is gradually increased in 16 or more hydrocarbon viscosity, is not suitable for the purpose of viscosity adjustment.In the case of saturated hydrocarbons, carbon number 9
~15 hydrocarbon is suitable.In addition, even unsaturated hydrocarbons, can also add the hydrocarbon with side chain.Wherein, it is easy from what is obtained
Degree, the adjustment effect of viscosity, preparation medicament mechanically or chemically stability from the viewpoint of, the 12 of the straight-chain hydrocarbons of carbon number 12
Alkane is suitable.
Even in addition, proportion be 1 or more granular or powdered solid medicine ingredient in the case of, it is of the invention
In water surface self-diffusion type Labor-saving drug, because the drug ingredient to be made to stable suspension, put by drug
When on the water surface, which is supported on by diffusion ingredient without being settled down in water on the water surface, and water surface self-diffusion type saves
Power chemical drug object is integrally spread on the water surface, so that the drug ingredient is evenly distributed to the entire water surface.
The suspended liquor of diffusion of the present invention can also be combined with solid matter, and it is in powdered, granular or piece in appearance to be processed into
The composition for realizing the two benches diffusion gradually can be also made in the solid of agent shape etc., but the present invention does not interfere these additions
Processing.
Invention effect
The present invention plays effect below because being above-mentioned composition.By by the composition of pesticide and fertilizer etc.
Property settings are unprecedented above-mentioned condition, even wide paddy field, as soon as by putting into a place from ridge, it can be by medicine
Product ingredient is uniformly delivered to more than 250m2Large area entire paddy field.For example, according to the present invention, as shown in figure 4, with
100g is diffused into 1000m2Above water surface.The present invention is conducted drugs to being realized by a local drug input
The Labor-saving of wide scope as a purpose, be repeated improve its effect innovation improve made of invent, but water environment certain
Drug-treated, drug input or drug distribution on the continuous water surface of one furrow are not limited to a place.
Further it is proposed that can be in a solid state by the drug ingredient for failing the solid utilized in previous water surface solvent
The practical pharmaceutically dosage form directly applied flexibly, and the medicament application method in the environment for intervening the water surface, can realize economy and drug
Spread the Labor-saving of operation.
Description of the drawings
Fig. 1 is (A) previous water surface solvent and the expansion of (B) of the invention and the comparison schematic diagram of disperse state.
Fig. 2 be the present invention water surface self-diffusion type Labor-saving drug and comparative example in the type and object of the drug ingredient that use
Property.
Fig. 3 is an example of the composition of the present invention and comparative example.
Fig. 4 is the result of the diffusion test (water surface) of the present invention and comparative example.
Fig. 5 is the result of the diffusion test (concentration) of water surface self-diffusion type Labor-saving drug.
Fig. 6 is the Herbicidal Testing Trials result managed in paddy field.
Fig. 7 be by the present invention water surface self-diffusion type Labor-saving medicament administration in actual paddy field when schematic diagram.
Specific implementation mode
In the following, with reference to attached drawing, detailed description of embodiments of the present invention.In addition, the invention is not limited in following
Embodiment.
Embodiment 1
Fig. 1 is the comparison schematic diagram of (A) previous water surface solvent 2 and the disperse state of (B) present invention.If by of the invention
Water surface self-diffusion type Labor-saving drug 1 be added dropwise, when being injected into the water surface, suspended, emulsification does not occur in water, but equably exists
The water surface diffuses to wide scope (two arrows).
Fig. 2 is the type and physical property of drug ingredient used in the present invention and comparative example.Using these substances as drug at
It point is suitably allocated, mixes diffusion ingredient, other additives, be prepared for showing test example shown in Fig. 3, comparative example
Each functional pesticidal preparations.
Fig. 3 is an example of the water surface self-diffusion type Labor-saving drug of the present invention and the composition of comparative example, and test example A-G is this
The embodiment of invention imparts the function of making drug ingredient be spread in the water surface using diffusion ingredient.On the other hand, only than
Compared with surfactant is added in example A, the function of emulsification suspended in water is assigned.
Silicone oil is oil-soluble, when being added in water surface self-diffusion type Labor-saving drug, a part of drug, such as
Here, diffusivity of the A6 particles on the water surface improves.
On the other hand, 1,2-PD is to expand certainly if being added to the water surface with all soluble compound in oil in water
It dissipates in type Labor-saving drug, is then suspended in diffusion of the particle of the metacetaldehyde in water surface self-diffusion type Labor-saving drug on the water surface
Property improve.
Fig. 4 is the result of the water surface self-diffusion type Labor-saving drug of the present invention and the diffusion test (water surface) of comparative example.
The preparation of preparation
With the prescription of test example shown in Fig. 3 and comparative example, the condition of about 150g is reached with total amount, to about 450mL
Capacity ball mill crushing container in weigh the pharmaceutical composition comprising drug ingedient and diffusion ingredient, further add
Stirring blade is arranged in the bead of the diameter 1mm of about 150g.It is loaded into ball mill main body, with about 1000rpm to drug
Composition stirring crushes 15 minutes, is at most stirred, is crushed 120 minutes or so according to state.To the content holes about 0.5mm
The stainless steel of diameter screens out bead, is prepared for uniform suspension.
In the case of other than a diameter of 1mm of the bead used, it can be removed with the sieve in aperture corresponding with the diameter
Remove bead.In order to crush the particle of dispersion thinner, the small bead of diameter is used, it is generally preferable to use 0.2mm~4mm
The glass of left and right or the pearl of other materials.
But in test example B and C, it is dissolved in diffusion ingredient because drug ingredient (substance) is equably mixed,
So not needing the pulverizing process, only carrying out mixing in a reservoir can prepare.
Comparative example B (commercially available products：It is not shown)
(drug ingredient of herbicide is suspended in water for commercial suspension agent contained by the drug ingredient A1 and A4 of acquirement herbicide
Preparation), be used as the raw material of comparative example B.With reference to the containing ratio of the A1 and A4, it is prepared for test example D and Comparative examples A.
By the way that said preparation to be diluted with water, the preparation for keeping the concentration of A1 and A4 consistent with test example D and Comparative examples A is as comparative example B.Though
It so confirms said preparation to be suspended in water, but its detailed prescription is not known.
The drug ingredient of the raw material of the comparative example B of acquirement contains weight %：
A1：30.5%,
A4：15.5%,
Other：Surplus,
The substance after 2.5 times is diluted with water, as test example B.
Therefore, the drug ingredient of comparative example B contains weight % and is：
A1：12.2%,
A4：6.2%.
Comparative example C is (commercially available：It is not shown)
The drug ingredient contains weight %：
A1：3.0%,
A2：9.0%,
A3：1.8%,
A4：1.0%,
Other：Surplus,
50g preparations are enclosed in 1 bag of water-soluble film bag respectively.Its application method is into paddy field with every 100m2Paddy field
1 bag of input.
The commercially available Jumbo rice herbicide for obtaining drug ingredient A1, A2, A3 and A4 comprising herbicide, is used as
Comparative example C.Because the containing ratio with reference to A1, A2, A3 and the A4 is prepared for test example A, in comparative example C, herbicide
The concentration of drug ingredient A1, A2, A3 and A4 be the 1/2 of test example A.It takes out and weighs the drug main body in enclosed water-soluble bag
Floatability particle, for testing.
The confirmation of water suspended
The water suspended of each drug about preparation adds about the 20 of 20 times of weight of drug early period into each drug
DEG C tap water, vibrate 5 minutes with the vibrating machine of about 5Hz, then in about 25 DEG C of standing at room temperature 3 minutes, confirm water and
Trial drug is separated into two-phase.In Comparative examples A-C, after same oscillating condition, 3 minutes are stood, the drug is by emulsifying, hanging
Turbid and stablize in water, the drug for confirming water and Comparative examples A-C is not separated into two-phase.As oil-type water surface solvent pin
" な げ こ body ト レ ボ Application " (registered trademark) for Mitsui Chemicals A Guluo companies (the Mitsui Chemicals ア グ ロ) system sold is also identical
Under the conditions of determine water suspended, but confirm under the same conditions, water and " な げ こ body ト レ ボ Application " (registered trademark) do not have
It is separated into two-phase.
The confirmation of water-soluble
Above-mentioned water suspended is further confirmed that sample continues the standing at room temperature 55 minutes at about 25 DEG C, is as a result confirmed
All do not change to test example and comparative example, does not dissolve similarly in water all.
Diffusion test (diffusible numerical computations)
Tap water is filled up to about the 70% of stainless steel pallet (55 × 40cm), with the suction pipe of polyethylene by test example and ratio
It is dripped compared with the preparation being prepared in example and it is made to fall on the center on the water surface.In the case of other than Comparative examples A, drip
Drug is spread in the entire water surface of stainless steel pallet immediately.Then 1 minute state after observation is dripped.Then, with same suction pipe
The medicament is added drop-wise in the beaker of empty 50mL, measures its weight.The minimum diffusion of 100g drugs is calculated based on the weight
Area.In the case of Comparative examples A, because not spread fully on the water surface, after dripping 1 minute, only diffuse to stainless
About 1% or so of steel tray.The weight for measuring a drop, calculates water surface diffusivity.By comparing test example D and Comparative examples A
As a result, understanding to be suspended in water and the water surface diffusivity of drug added with surfactant reduces.
Fig. 5 is the result of the diffusion test (concentration) of the water surface self-diffusion type Labor-saving drug of the present invention.It is being paved with water simultaneously
It has carried out in smooth paddy field, has prepared the experiment furrow of the rectangular shape of 3 furrow 1m × 10m.
Then, by comparative example B, (suspend (SC：Suspension Concentrate) agent), test example D (diffusion it is suspended
(SS：Spreading Suspension) agent), Comparative examples A (oil dispersed (OD：Oil Dispersion) agent) drug with each 1g
Drop in one end of each furrow.
Then, the Soil surface water and soil in the place of 2m, 5m and 8m are sampled from the end of dripping, to the drug of herbicide
Ingredient A4 has carried out concentration analysis.It fetches water to the water of the water surface in paddy field after 1 day after drug-treated, after treatment after 3 days
Carry out soil sample.
Distinguish：The drug ingredient transporting of the drug of comparative example B as aqueous suspension is minimum, the drug of Comparative examples A
Drug ingredient transporting take second place, the drug ingredient transporting of test example D is best.According to the result：It does not dissolve in water
And it does not emulsify excellent in drug ingredient transporting with the water surface self-diffusion type Labor-saving drug of the suspended present invention.
Fig. 6 is the Herbicidal Testing Trials in the management paddy field of the diffusion test (activity of weeding) of water surface self-diffusion type Labor-saving drug
As a result.Fig. 6 (A) is the test example A's as a result, Fig. 6 (B) is the result of comparative example C (Jumbo rice herbicide) of the present invention.
In being paved with water and having carried out smooth paddy field, the experiment furrow of the rectangular shape of 2 furrow 1m × 10m and right are prepared
According to the furrow without processing.By test example A and commercially available weeding Jumbo rice with herbicide (comparative example C) respectively with 2.5g and
5g puts into one end of each experiment furrow, so that A1, A2, A3 are identical with A4 concentration.
Then, after 22 days, for the situation occurred of the weeds of each furrow, every 1m until playing 10m from drug input end,
Weed control situation (preventing and kill off valence) has been investigated to respondent weeds (barnyard grass, firefly Lin, water high mallow and annual width leaf weed).
Bearing status without processing furrow and the respondent weeds of equal extent is denoted as 0, respondent weeds are complete
Withered state is denoted as 100 (full marks), the weed control situation of each trial zone when researcher has investigated day by visual observation,
It is evaluated with 100 points of full marks.Actual herbicidal effect is also evaluated, it is known that：The drug ingredient of test example A (A)
Transporting is more excellent than the Jumbo rice herbicide of commercially available product, i.e. comparative example C (B).
Fig. 7 be by the present invention water surface self-diffusion type Labor-saving medicament administration in actual paddy field when schematic diagram.?
1500m2Paddy field in carry out Rice Cropping, as shown in fig. 7, setting the furrow of small no processing.After it is 14 days, by 375g
The drug of test example A is all dropped in 1 place (spider lable) from ridge.
Later, after 28 days with 52 days after, investigated the herbicidal effect of the weeds in addition to rice.With without processing furrow phase
Than confirming：In paddy field, the weeds in addition to rice are carried out weeding by whole face completely.
In addition, being shown by the result：In the case of the water surface self-diffusion type Labor-saving drug of test example A, due to its water
Face diffusion function, the drug ingredient with activity of weeding contained in test example A are automatically evenly supplied to whole after treatment
In a paddy field.
On the other hand, using commercially available comparative example B, it is necessary to be put into around paddy field or in paddy field
The Jumbo rice herbicide packet of 15 packets.In view of this kind of situation, it was confirmed that water surface self-diffusion type Labor-saving drug of the invention exists
Drug, which is spread, has high Labor-saving performance in operation.
Symbol description
1 water surface self-diffusion type Labor-saving drug
2 water surface solvents
3 waters surface
Claims (14)
1. a kind of water surface self-diffusion type Labor-saving drug, it is the drug ingredient and liquid including at least liquid, grain or powdery
The mixture of mobility made of diffusion ingredient, diffusion ingredient dissolving or be adsorbed in the drug ingredient or
The coating drug ingredient of person, makes the drug ingredient not settle and be supported on the water surface, makes the drug ingredient in institute
State water surface diffusion；
And it is that the mixture of the mobility shakes in 20 times of weight, temperature range higher than 0 DEG C and less than 40 DEG C water
After swinging mixing, the two-phase with the water is separated within 3 minutes, similarly insoluble, suspended or emulsification drug；
Have the two benches diffusion mechanism gradually being made of the diffusion mechanism of the diffusion mechanism of horizontal direction and vertical direction,
The diffusion mechanism of the horizontal direction, which is that one from the drug in water environment is local, intensively to be lighted, and weight is utilized
Power and the diffusion ingredient act on the adsorption of the water surface, make the drug ingredient in the uniform distribution of the water surface；
The diffusion mechanism of the vertical direction is that the drug ingredient is made slow mechanism dissolved and to be spread into water from the water surface, and evening
In the diffusion of the horizontal direction, the water environment bottom is reached from the water surface.
2. water surface self-diffusion type Labor-saving drug as described in claim 1, which is characterized in that the density ratio of the drug ingredient
Water is big.
3. water surface self-diffusion type Labor-saving drug as described in claim 1, which is characterized in that make the drug ingredient diffusion
The diffusion ingredient of liquid passes through comprising selected from the compound in the molecule with ester bond, amido bond, ehter bond, carboxyl, hydroxyl
1 kind or more and formed.
4. water surface self-diffusion type Labor-saving drug as described in claim 1, which is characterized in that also comprising straight-chain hydrocarbons as viscosity
Regulator.
5. water surface self-diffusion type Labor-saving drug as described in claim 1, which is characterized in that make the drug ingredient diffusion
The diffusion ingredient of liquid be selected from soybean oil, Castor oil, linseed oil, 2-Ethylhexyl Alcohol, oleic acid and methyl oleate 1
Kind or two or more.
6. water surface self-diffusion type Labor-saving drug as described in claim 1, which is characterized in that the drug of the grain or particle at
It is to show the solids of 1mm average grain diameters below, and be suspended in the diffusion ingredient to divide.
7. water surface self-diffusion type Labor-saving drug, which is characterized in that the diffusion is by water surface self-diffusion described in claim 1
Type Labor-saving drug is dropped in a place, and under conditions of there is no flow, and area is more than 250m2Diffusion.
8. water surface self-diffusion type Labor-saving drug as described in claim 1, which is characterized in that saved from the water surface self-diffusion type
The water surface self-diffusion type Labor-saving drug of the emulsibility surfactant comprising 1~20 weight % is excluded in power chemical drug object.
9. water surface self-diffusion type Labor-saving drug as described in claim 1, which is characterized in that saved from the water surface self-diffusion type
The water surface self-diffusion type Labor-saving drug of the surfactant comprising 1~20 weight % is excluded in power chemical drug object.
10. a kind of Labor-saving drug distributing method, which is characterized in that by water surface self-diffusion type Labor-saving described in claim 1
Infusion of medicine makes it uniformly be spread in the water surface to the water environment water surface, and the drug ingredient is made to be uniformly spread to water environment
In.
11. Labor-saving drug distributing method as claimed in claim 10, which is characterized in that the water environment is paddy field.
12. a kind of Labor-saving drug distributing method, which is characterized in that make water surface self-diffusion type Labor-saving drug pass through gradually two
Drug ingredient is diffused into water environment by stage diffusion mechanism；
The water surface self-diffusion type Labor-saving drug is mobility made of the diffusion ingredient comprising drug ingredient and liquid
Mixture, the diffusion ingredient dissolving of the liquid or be adsorbed in the drug ingredient or the coating drug ingredient,
So that the drug ingredient is not settled and is supported on the water surface, the drug ingredient is made to be spread on the water surface；
The two benches diffusion mechanism gradually is：The water surface self-diffusion type Labor-saving infusion of medicine is arrived into water environment first
The water surface makes it in water surface diffusion profile in the horizontal direction, and then, it is described to be later than to make the water surface self-diffusion type Labor-saving drug
The mode of diffusion profile and reaches the water environment along vertical direction slow mechanism dissolved from the water surface to water in horizontal direction
Bottom.
13. Labor-saving drug distributing method as claimed in claim 12, which is characterized in that there is no the water environments of flow
Under, by the way that the water surface self-diffusion type Labor-saving drug is dropped in a place, the drug ingredient is diffused into more than described
The water surface area 100m of water environment2Range.
14. Labor-saving drug distributing method as claimed in claim 12, which is characterized in that there is no the water environments of flow
Under, by the way that the water surface self-diffusion type Labor-saving drug is dropped in a place, the drug ingredient is diffused into more than described
The water surface area 250m of water environment2Range.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2016050849A JP6090815B1 (en) | 2016-03-15 | 2016-03-15 | Self-water diffusion type labor-saving drug |
| JP2016-050849 | 2016-03-15 | ||
| PCT/JP2017/007119 WO2017159296A1 (en) | 2016-03-15 | 2017-02-24 | Water-surface self-spreading type labor-saving chemical |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN108777955A true CN108777955A (en) | 2018-11-09 |
Family
ID=58261910
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201780016332.0A Pending CN108777955A (en) | 2016-03-15 | 2017-02-24 | Water surface self-diffusion type Labor-saving drug |
Country Status (3)
| Country | Link |
|---|---|
| JP (2) | JP6090815B1 (en) |
| CN (1) | CN108777955A (en) |
| WO (1) | WO2017159296A1 (en) |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP6090815B1 (en) * | 2016-03-15 | 2017-03-08 | 愼一 清水 | Self-water diffusion type labor-saving drug |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH06336402A (en) * | 1993-05-26 | 1994-12-06 | Nippon Nohyaku Co Ltd | Composition for control of rice sheath blight |
| JP2000290104A (en) * | 1999-04-06 | 2000-10-17 | Koodekku Chemical:Kk | Animal repellent and production thereof |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| JP6090815B1 (en) * | 2016-03-15 | 2017-03-08 | 愼一 清水 | Self-water diffusion type labor-saving drug |
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2016
- 2016-03-15 JP JP2016050849A patent/JP6090815B1/en active Active
-
2017
- 2017-02-24 WO PCT/JP2017/007119 patent/WO2017159296A1/en active Application Filing
- 2017-02-24 CN CN201780016332.0A patent/CN108777955A/en active Pending
- 2017-02-24 JP JP2017551345A patent/JP6353611B2/en active Active
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH06336402A (en) * | 1993-05-26 | 1994-12-06 | Nippon Nohyaku Co Ltd | Composition for control of rice sheath blight |
| JP2000290104A (en) * | 1999-04-06 | 2000-10-17 | Koodekku Chemical:Kk | Animal repellent and production thereof |
Also Published As
| Publication number | Publication date |
|---|---|
| JP6090815B1 (en) | 2017-03-08 |
| JP2017165666A (en) | 2017-09-21 |
| JP6353611B2 (en) | 2018-07-04 |
| WO2017159296A1 (en) | 2017-09-21 |
| JPWO2017159296A1 (en) | 2018-04-19 |
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