CN108752364A - 一种对甲氧基取代含吡唑结构的螺[吲哚嗪-异噁唑啉]衍生物及其制备方法与应用 - Google Patents
一种对甲氧基取代含吡唑结构的螺[吲哚嗪-异噁唑啉]衍生物及其制备方法与应用 Download PDFInfo
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- CN108752364A CN108752364A CN201810611619.4A CN201810611619A CN108752364A CN 108752364 A CN108752364 A CN 108752364A CN 201810611619 A CN201810611619 A CN 201810611619A CN 108752364 A CN108752364 A CN 108752364A
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- isoxazoline
- indolizine
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
- C07D498/20—Spiro-condensed systems
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
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- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
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Abstract
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CN201810611619.4A CN108752364B (zh) | 2018-06-14 | 2018-06-14 | 一种对甲氧基取代含吡唑结构的螺[吲哚嗪-异噁唑啉]衍生物及其制备方法与应用 |
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CN201810611619.4A CN108752364B (zh) | 2018-06-14 | 2018-06-14 | 一种对甲氧基取代含吡唑结构的螺[吲哚嗪-异噁唑啉]衍生物及其制备方法与应用 |
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CN108752364A true CN108752364A (zh) | 2018-11-06 |
CN108752364B CN108752364B (zh) | 2019-10-15 |
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Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN109776555A (zh) * | 2019-02-28 | 2019-05-21 | 贵州大学 | 山酮素骨架拼接异噁唑与双螺环氧化吲哚衍生物及其制备方法及应用 |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN106795157A (zh) * | 2014-10-08 | 2017-05-31 | 莱德克斯制药公共有限公司 | 作为Wnt信号传送途径的抑制剂的N‑吡啶基乙酰胺衍生物 |
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2018
- 2018-06-14 CN CN201810611619.4A patent/CN108752364B/zh active Active
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN106795157A (zh) * | 2014-10-08 | 2017-05-31 | 莱德克斯制药公共有限公司 | 作为Wnt信号传送途径的抑制剂的N‑吡啶基乙酰胺衍生物 |
Non-Patent Citations (3)
Title |
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SHAOWEI ZHANG,等: "Synthesis of novel spiro(indolizine-pyrazole) derivatives via 1,3-dipolar cycloaddition of nitrilimine", 《JOURNAL OF CHEMICAL RESEARCH》 * |
TING-HONG FEI,等: "Synthesis and Characterization of Novel 1,2,4-oxadiazoline Derivatives Containing Pyrazole Moiety by 1,3-Dipolar Cycloaddition", 《JOURNAL OF HETEROCYCLIC CHEMISTRY》 * |
余虹宇,等: "1,3一偶极环加成反应合成螺[吲哚嗪一异噁唑啉]类化合物", 《湖南科技大学学报(自然科学版)》 * |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN109776555A (zh) * | 2019-02-28 | 2019-05-21 | 贵州大学 | 山酮素骨架拼接异噁唑与双螺环氧化吲哚衍生物及其制备方法及应用 |
CN109776555B (zh) * | 2019-02-28 | 2022-05-13 | 贵州大学 | 山酮素骨架拼接异噁唑与双螺环氧化吲哚衍生物及其制备方法及应用 |
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