CN108728521A - A kind of PCR instrument and its hot lid elevating mechanism - Google Patents

A kind of PCR instrument and its hot lid elevating mechanism Download PDF

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Publication number
CN108728521A
CN108728521A CN201810614004.7A CN201810614004A CN108728521A CN 108728521 A CN108728521 A CN 108728521A CN 201810614004 A CN201810614004 A CN 201810614004A CN 108728521 A CN108728521 A CN 108728521A
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China
Prior art keywords
lid
elevating mechanism
heat
hot
guide surface
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Inventor
郭洪菊
马丽
罗强
敬娟
黄国亮
王磊
邢婉丽
程京
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CapitalBio Corp
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CapitalBio Corp
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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844Nucleic acid amplification reactions
    • C12Q1/686Polymerase chain reaction [PCR]

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Commercial Cooking Devices (AREA)

Abstract

The present invention discloses a kind of PCR instrument and its hot lid elevating mechanism, wherein, the hot lid elevating mechanism includes holder and is equipped with the pull module of EP pipes, heat lid is slidable in the vertical direction cooperation with the holder, the pull module is equipped with guide surface, the guide surface includes horizontal high section, low section of level and is connected to changeover portion between the two, the heat lid is supported in the guide surface, and the pull module can change the Support Position of the heat lid and the guide surface in the displacement of the guide surface extending direction;When the pull module is in extraction state, the heat lid is supported in the high section of level;When the pull module is in pushing status, the heat lid is supported in low section of the level, and compresses the pipe lid of the EP pipes.The problem of hot lid elevating mechanism provided by the present invention completes the upper and lower displacement of heat lid by the pulling motion of pull module, and operation is more quick, and is not necessarily to motor, and there is no power consumption, structure is also relatively simple.

Description

A kind of PCR instrument and its hot lid elevating mechanism
Technical field
The present invention relates to round pcr field more particularly to a kind of PCR instrument and its hot lid elevating mechanisms.
Background technology
PCR (Polymerase Chain Reaction, i.e. PCR) is using archaeal dna polymerase to specific DNA fragmentation is amplified the Protocols in Molecular Biology of amplification, and PCR instrument is to realize the instrument of round pcr.
PCR instrument includes mainly the heating and cooling structure of lower part, the heat on top is covered and optical module, and the main function of heat lid is anti- Only liquid influences light path detection in EP pipes (eppendorf is managed, i.e. centrifuge tube) top condensation, and to realize that this function will Heat lid is asked to compress the pipe lid of EP pipes.Currently, the conventional mechanism for driving heat lid to push is driven using motor, motor is removed Except, it is also necessary to corresponding transmission parts are set, convert the rotation of motor to linear displacement, and coordinate electrical equipment, soft Part support just can guarantee compressing in place for heat lid, and the structure of this driving mechanism is complex, and power consumption is larger, and controls heat and cover It is mobile to be detached from or the process of compressing pipe lid need to take a substantial amount of time, can not fast operating.
Therefore, how a kind of hot lid elevating mechanism simple in structure, power consumption is low and swift to operate is provided, is still this field Technical staff's technical problem urgently to be resolved hurrily.
Invention content
The object of the present invention is to provide a kind of PCR instrument and its hot lid elevating mechanisms, wherein the structure of the hot lid elevating mechanism It is relatively simple, it is swift to operate, and there is no power consumption the problem of.
In order to solve the above technical problems, the present invention provides a kind of hot lid elevating mechanism of PCR instrument, including holder and it is equipped with The pull module of EP pipes, the heat lid are slidable in the vertical direction cooperation with the holder, and the pull module is equipped with guide surface, institute It states guide surface to include horizontal high section, low section of level and be connected to changeover portion between the two, the heat lid is supported in the guiding Face, the pull module can change the support level of the heat lid and the guide surface in the displacement of the guide surface extending direction It sets;When the pull module is in extraction state, the heat lid is supported in the high section of level;The pull module is in push-in When state, the heat lid is supported in low section of the level, and compresses the pipe lid of the EP pipes.
Using the above structure, heat lid is setting of floating, and can be slided in above-below direction, and heat lid is also supported in pumping The guide surface of drawing-die block, which includes the height high section of level straggly and low section of level, when to pull module execution pull When operation, heat lid can support the different location in guide surface, to change the height of heat lid.
Specifically, when it is to be moved to horizontal high section by horizontal low section that heat, which covers opposite pull module, pull module is in Extraction state, heat lid will be moved up along holder, so that EP pipes are exposed, can facilitate the operations such as taken, placed to EP pipes;When heat is covered Opposite pull module is when being moved to low section horizontal by horizontal high section, and pull module is in pushing status, and heat lid will be under holder It moves, and relies on gravity nature compressing pipe lid, the temperature of heat lid can effectively be transferred to the top of EP pipes, be condensed to avoid EP tube tops portion Liquid.
Compared with the prior art, hot lid elevating mechanism provided by the present invention, by the pulling motion of pull module come complete At the upper and lower displacement of heat lid, operation is more quick;Whole operation process can be manually completed by Field Force, be set without motor etc. Standby, the problem of power consumption is not present, and overall structure is relatively simple.
Optionally, further include elastic component, the holder is fixed in the lower end of the elastic component, and upper end can tense downwards branch Support the heat lid in low section of the level.
Optionally, further include driver plate, one end of the driver plate is installed on the heat lid, the other end and the elastic component Upper end be connected, and the heat lid is coordinated by the driver plate and the bracket slide.
Optionally, further include wing plate, the wing plate be installed on it is described heat lid lateral ends, and with the driver plate phase Even.
Optionally, the changeover portion is smooth surface.
Optionally, further include rolling member, the rolling member is installed on the heat lid, and the heat lid passes through the rolling member branch It supports in the guide surface, and is acted along the guide surface by the rolling member.
Optionally, further include position sensor, the position sensor is used to monitor the position of the heat lid.
Optionally, the position sensor is photoelectric sensor, including the transmitter and receiver being oppositely arranged, the two are equal It is installed on the holder;The photoelectric sensor further includes the photoelectricity catch for being installed on the heat lid, the photoelectricity catch cooperation The receiver, the transmitter can monitor the position of the heat lid.
Optionally, further include bottom plate, the holder is fixed on the bottom plate, and the pull module is slidably connected to the bottom Plate.
The present invention also provides a kind of PCR instrument, including heat lid, the heat lid has above-mentioned hot lid elevating mechanism.
Since above-mentioned hot lid elevating mechanism has been provided with technique effect as above, then, there is the hot lid elevating mechanism PCR instrument also when having similar technique effect, therefore this will not be repeated here.
Description of the drawings
Fig. 1 is a kind of structural schematic diagram of specific implementation mode of hot lid elevating mechanism provided by the present invention;
Fig. 2 is the connection structure diagram of heat lid and holder;
Fig. 3 is the structural schematic diagram of pull module;
When Fig. 4 is in extraction state for pull module, heat is covered and the connection structure schematic diagram of pull module;
When Fig. 5 is in pushing status for pull module, heat is covered and the connection structure schematic diagram of pull module.
The reference numerals are as follows in Fig. 1-5:
1 holder;
2 pull modules, 21EP pipes, 211 tube bodies, 212 pipe lids, 22 guide surfaces, 221 horizontal high sections, 222 low section of levels, 223 Changeover portion, 23 drawing frames, 24 pull bodies, 241 pull positions, 25 first sliding rails;
3 heat lids;
4 elastic components;
5 driver plates;
6 wing plates;
7 rolling members;
8 photoelectric sensors, 81 transmitters, 82 receivers, 83 photoelectricity catch;
9 bottom plates, 91 second sliding rails.
Specific implementation mode
It is below in conjunction with the accompanying drawings and specific real in order to make those skilled in the art more fully understand technical scheme of the present invention Applying example, the present invention is described in further detail.
The words such as " first " described herein, " second ", be merely for convenience of description scheme same or like two with On structure or component, be not offered as certain particular determination to sequence.
The nouns of locality, the orientation being all based in Fig. 1 and the position relationship such as "upper" described herein, "lower", " cross ", in Fig. 1 Upper and lower directions be upper and lower directions described herein, also refer to short transverse, the left and right directions in Fig. 1 is laterally, in water In the plane and perpendicular direction of left and right directions is longitudinal and guide surface extending direction, i.e. pull direction;In fact, Fig. 1 In orientation and position relationship be hot lid elevating mechanism provided by the present invention orientation in practical applications and position relationship.
Please refer to Fig.1 a kind of structural representation for specific implementation mode that -5, Fig. 1 is hot lid elevating mechanism provided by the present invention Figure, Fig. 2 are that heat is covered and the connection structure diagram of holder, Fig. 3 are the structural schematic diagram of pull module, and Fig. 4 is that pull module is in pumping When doing well, heat lid and the connection structure schematic diagram of pull module, when Fig. 5 is that pull module be in pushing status, heat is covered and pull The connection structure schematic diagram of module.
As shown in Figs. 1-5, the present invention provides a kind of hot lid elevating mechanism of PCR instrument, including holder 1 and pull module 2, heat Lid 3 is slidable in the vertical direction cooperation with holder 1, to realize the setting that floats up and down of hot lid 3.Pull module 2 is equipped with EP pipes 21, The EP pipes 21 include tube body 211 and pipe lid 212, and pull module 2 is additionally provided with guide surface 22, and hot lid 3 can be supported in the guide surface 22, guide surface 22 includes low section 222 of the high section 221 of height level straggly and level, and the two is mutually parallel, and is horizontal plane, So that when without outer force effect hot lid 3 can be steadily placed at horizontal high section 221 or it is low section 222 horizontal on, horizontal high 221 He of section Changeover portion 223 is equipped between low section 222 horizontal, when executing draw operation to pull module 2, hot lid 3 can be with respect to pull module 2 Displacement is carried out, and is supported in the different location of guide surface 22, to change the height of hot lid 3.It is appreciated that above-mentioned horizontal plane is Approximately horizontal plane, the not level in absolute sense, as long as ensureing to be supported in horizontal high section 221 or horizontal low section 222 of hot lid 3 It can stablize, not shake back and forth.
Specifically, when hot lid 3 is moved to horizontal high section 221 with respect to pull module 2 by horizontal low section 222, pull mould Block 2 is in extraction state, as shown in figure 4, hot lid 3 will be moved up along holder 1, EP pipes 21 are relatively distant from hot lid 3, can facilitate and be managed to EP 21 the operations such as are taken, are placed;When hot lid 3 is moved to low section 222 horizontal with respect to pull module 2 by horizontal high section 221, take out Drawing-die block 2 will be in pushing status, as shown in figure 5, hot lid 3 will be moved down along holder 1, and rely on gravity nature compressing pipe lid 212, The temperature of hot lid 3 can effectively be transferred to the top of EP pipes 21, to avoid 21 top coagulating liq of EP pipes.
Compared with the prior art, hot lid elevating mechanism provided by the present invention, by the pulling motion of pull module 2 come complete At the upper and lower displacement of hot lid 3, operation is more quick, time-consuming shorter, and whole operation process can be manually completed by Field Force, nothing The problem of needing the equipment such as motor, power consumption is not present, overall structure is also relatively simple.
In guide surface 22, changeover portion 223 can be smooth surface, alternatively, the main body of the changeover portion 223 can be oblique Face can be seamlessly transitted with horizontal high section 221 and horizontal low section 222 of junction, to ensure that hot lid 3 can be swimmingly in water Flat high section 221 and it is low section 222 horizontal between carry out displacement.
It may be noted that the embodiment of the present invention not restriction level high section 221 and it is low section 222 horizontal between difference in height, i.e., Falling head in above-below direction when hot lid 3 slides into low section 222 horizontal from horizontal high section 221 is not limited, as long as ensureing hot lid 3 The pipe lid 212 of EP can be carried out when dropping to low section 222 horizontal effectively to compress.
For ease of description, can by horizontal high section 221 and it is low section 222 horizontal between difference in height be defined as H0, and will be in The lower surface of the hot lid 3 of horizontal high section 221 is upper with the pipe lid 212 (at this point, pipe lid 212 has been plugged in tube body 211) of EP pipes Difference in height between surface is defined as Ht, when implementing, H0H can be more thant, i.e. hot lid 3 not yet slides into low section 222 horizontal, i.e., It can be in contact with the pipe lid 212 of EP pipes, remaining H0-HtDifference in height be that pressing force (gravity of hot lid 3 and is hit by a bullet hereinafter Property part 4 pulling force) operating distance, be more advantageous to the compression for ensureing EP pipe pipes lid 212;But it should be noted that H0-HtHeight Difference can not be excessive, to avoid pipe lid 212 has compressed and hot lid 3 cannot be supported in horizontal low section 222 of situation.It is specific and Speech, above-mentioned H0It could be provided as 2.5mm, Ht2mm is could be provided as, to form the compression distance of 0.5mm.
Further, it can also include elastic component 4, it is first which is specifically as follows the elasticity such as spring or stretch cord Part.The lower end of elastic component 4 can be fixed on holder 1, and upper end can be connected with hot lid 3, and the elastic component 4 can be in and draw always State is stretched, i.e., a downward pulling force is generated to hot lid 3 always, which can coordinate its own gravity collective effect of hot lid 3, with Ensure that hot lid 3 can more closely be pressed on pipe lid 212 when pushing and pulling module 2 and being pushed into.
Can also include driver plate 5, the quantity of driver plate 5 can be two, and be respectively arranged in specific scheme 3 transverse ends portion of hot lid, elastic component 4 can be connected to driver plate 5 and holder 1.Driver plate 5 is equivalent to pinboard, and hot lid 3 can be with It is slidably connected by driver plate 5 and the holder 1 of both sides.
It is directly slidably connected with its transverse ends and holder 1 so set, can avoid hot lid 3, that is to say, that without in heat The sliding fit of the transverse ends processing forms such as sliding rail or sliding slot of lid 3, directly can be with this hair using common hot lid 3 Bright provided hot lid elevating mechanism is used cooperatively, and is conducive to the general applicability for improving the hot lid elevating mechanism;Meanwhile it can also keep away Exempt to influence the function of hot lid 3, service life to the direct abrasion of hot lid 3, influences to slide smooth when driver plate 5 generates abrasion Property when, can directly replace driver plate 5, without influence as main body hot lid 3 normal use.
It may be noted that the above-mentioned scheme being slidably matched using driver plate 5 and holder 1, is only the embodiment of the present invention A kind of preferred embodiment, can not be as the restriction of the practical range to hot lid elevating mechanism provided by the present invention;In fact, will The scheme that hot lid 3 is directly slidably connected with holder 1 is similarly present invention scheme claimed.
In the opposite face of driver plate 5 and holder 1, one can be equipped with sliding rail, and another one can be equipped with the cunning to match Slot, to realize being slidably matched for the two.Sliding slot can be necking slot, i.e., notch size is small and slot inside dimension is big, such as T-slot, ladder Shape slot, L-shaped groove, cydariform slot or serrated slot etc., correspondingly, sliding rail may be that head is big, the tail portion (connecting pin with driver plate 5 Portion) small clamp rail, when ensureing that sliding rail is plugged in sliding slot, it is merely able to be slided in the extending direction of sliding slot, is unable to edge Non-slip direction is deviate from from sliding slot, advantageously ensures that the reliability being slidably connected.
But it should be noted that in embodiments of the present invention, since laterally there are two holders 1 to be slided with hot lid 3 Dynamic cooperation, and be additionally provided with pull module 2 between two stands 1 and hot lid 3 is supported, by regulating and controlling the horizontal spacing of two stands 1, The dislocation of glide direction is actually less prone in sliding process for hot lid 3 and caused sliding rail takes off from sliding slot therefrom The situation gone out.Therefore, when producing design, simple rectangular channel may be used in sliding slot, and sliding rail can be that the rectangle to match is slided Item can equally ensure driver plate alternatively, above-mentioned sliding rail can also be substituted using one or several spaced sliding blocks 5 with the reliable sliding of holder 1.
The transverse ends portion of hot lid 3 can also be connected with wing plate 6, and above-mentioned driver plate 5 can pass through wing plate 6 and 3 phase of hot lid Even.By the setting of above-mentioned wing plate 6, the lateral dimension of hot lid 3 can be expanded, it is straight to avoid components such as driver plate 5, elastic components 4 The space occupied immediately below hot lid 3 is connect, can be that the installation of pull module 2 and pull module 2 are provided with contacting for hot lid 3 The space of bigger.
Dismountable connection types such as screw connection may be used between wing plate 6 and hot lid 3 and driver plate 5, alternatively, Can also directly using being welded and fixed, specifically can according to actual needs depending on.In embodiments of the present invention, it is preferred to use spiral shell Follow closely the scheme of connection, so, on the one hand, welding can be reduced, to avoid influence of the welding to hot lid 3, another aspect, can facilitate into The operations such as row dismounting, repair and replacement.
As shown in Fig. 2, hot lid elevating mechanism provided by the present invention can also include rolling member 7, which specifically can be with For the rolling element that idler wheel, rolling bearing etc. are common, it can be installed on hot lid 3 by driver plate 5 above-mentioned or wing plate 6, Hot lid 3 can be supported in guide surface 22 by rolling member 7, and by rolling member 7 on guide surface 22 opposite pull module 2 into line position It moves.The both lateral sides of hot lid 3 can be equipped with rolling member 7, and the quantity of the rolling member 7 of both sides can be one, or It is multiple, it can specifically be set according to actual needs.
In addition to the scheme of above-mentioned rolling, the scheme being slidably matched can also be used between hot lid 3 and guide surface 22, for example, Can be arranged on guide surface 22 with guide surface 22 have identical lifting trend guide groove, then can wing plate 6 lower section (or Person is directly in the lower section of hot lid 3) setting sliding block, sliding block can be plugged in guide groove, and can be slided in guide groove, to realize Relative displacement between hot lid 3 and pull module 2.
Comparatively, the opposite position between hot lid 3 and pull module 2 may be implemented in the scheme of above-mentioned rolling and sliding It moves, and uses the scheme rolled that can avoid clamping stagnation of the pull module 2 during push-in or pull-out to a greater degree, be more advantageous to Ensure the smoothness, reliability of relative displacement between hot lid 3 and pull module 2.
Further, it can also can be used for monitoring the position of hot lid 3 including position sensor, the position sensor, specifically It is the height and position for monitoring hot lid 3, to facilitate system to judge the state of current hot lid 3 and pull module 2.
Specifically, the position sensor can be photoelectric sensor 8, in embodiments of the present invention, used photoelectricity Sensor 8 is correlation type sensor, including one group of transmitter 81, receiver 82 and photoelectricity gear being used cooperatively being oppositely arranged Piece 83, transmitter 81, receiver 82 can be installed on holder 1, and photoelectricity catch 83 can be installed on hot lid 3, specifically install In wing plate 6, and displacement can be synchronized with hot lid 3.
It still using Fig. 2 as visual angle, carves at the beginning, a part for photoelectricity catch 83 can be located at transmitter 81 and receiver 82 Between, to block a part of optical signal, with the displacement of hot lid 3, photoelectricity catch 83 can synchronous shift, the light letter blocked Number quantity can also change, by counting the variation of the optical signal received by receiver 82, current hot lid 3 can be calculated Height and position.
Photoelectricity catch 83 may include occlusion part and mounting portion, and occlusion part can partly be located at transmitter 81 and receiver 82 Between, and mounting portion then can be used for being connected with wing plate 6.Mounting portion can be equipped with mounting hole, and the connector of the forms such as screw can Across the mounting hole and it is connected to wing plate 6, to fix the photoelectricity catch 83.Above-mentioned mounting hole is specifically as follows along the vertical direction The strip-shaped hole of extension, when mounted, connector are securable to the different location of strip-shaped hole, to adjust initial time photoelectricity catch 83 With the relative position of transmitter 81 and receiver 82.
As shown in figure 3, and in conjunction with Fig. 1, pull module 2 may include pull body 24 and drawing frame 23, and EP pipes 21 are installed on Pull body 24, pull body 24 are fixed on drawing frame 23, and guide surface 22 above-mentioned can be set to drawing frame 23.It can on pull body 24 Pull position 241 is arranged, the drawing hole or pull handle that Field Force's palm can pass through can be set on the pull position 241 Deng being operated to pull module 2 with facilitating.
Hot lid elevating mechanism provided by the present invention can also include bottom plate 9, i.e. pedestal, holder 1 can be fixed on bottom plate 9, Pull module 2 can be slidably matched by drawing frame 23 and bottom plate 9, specifically, the first cunning can be arranged in the bottom surface of pull module 2 The second sliding rail 91 can be arranged in the upper surface of rail 25, bottom plate 9, and two sliding rails can match, to realize that the pull of pull module 2 is grasped Make.Alternatively, the second above-mentioned sliding rail 91 can also be set to holder 1, you can with being slidably matched by pull module 2 and holder 1, To realize the draw operation of pull module 2.
It is excessive to avoid pull module 2 from extracting out or being pushed into, the forms such as limiting plate, limited block can also be set on bottom plate 9 Locating part, when pull module 2 moves to extreme position, above-mentioned locating part can to pull module 2 carry out backstop, with limit Determine the maximum withdrawn position of pull module 2 and maximum push-in position.
The present invention also provides a kind of PCR instrument, including hot lid 3, which may be used involved by the respective embodiments described above Hot lid elevating mechanism.
Since above-mentioned hot lid elevating mechanism has been provided with technique effect as above, then, using the hot lid elevating mechanism PCR instrument also when having similar technique effect, therefore this will not be repeated here.
It the above is only the preferred embodiment of the present invention, it is noted that those skilled in the art are come It says, various improvements and modifications may be made without departing from the principle of the present invention, these improvements and modifications also should be regarded as Protection scope of the present invention.

Claims (10)

1. a kind of hot lid elevating mechanism of PCR instrument, which is characterized in that including holder (1) and be equipped with EP manage (21) pull mould Block (2), heat lid (3) are slidable in the vertical direction cooperation with the holder (1), and the pull module (2) is equipped with guide surface (22), institute Guide surface (22) is stated to include horizontal high section (221), horizontal low section (222) and be connected to changeover portion between the two (223), it is described Heat lid (3) is supported in the guide surface (22), and the pull module (2) can in the displacement of the guide surface (22) extending direction Change the Support Position of the heat lid (3) and the guide surface (22);
When the pull module (2) is in extraction state, the heat lid (3) is supported in the high section of level (221);The pull When module (2) is in pushing status, the heat lid (3) is supported in the level low section (222), and compresses the EP pipes (21) Pipe lid (212).
2. the hot lid elevating mechanism of PCR instrument according to claim 1, which is characterized in that further include elastic component (4), the bullet Property part (4) lower end be fixed on the holder (1), upper end can pull down compact schemes in the heat lid of low section of the level (222) (3)。
3. the hot lid elevating mechanism of PCR instrument according to claim 2, which is characterized in that further include driver plate (5), the biography One end of movable plate (5) is installed on the heat lid (3), and the other end is connected with the upper end of the elastic component (4), and the heat lid (3) It is slidably matched by the driver plate (5) and the holder (1).
4. the hot lid elevating mechanism of PCR instrument according to claim 3, which is characterized in that further include wing plate (6), the wing plate (6) lateral ends of the heat lid (3) are installed on, and are connected with the driver plate (5).
5. the hot lid elevating mechanism of PCR instrument according to claim 1, which is characterized in that the changeover portion (223) is smooth song Face.
6. according to the hot lid elevating mechanism of any one of the claim 1-5 PCR instruments, which is characterized in that further include rolling member (7), the rolling member (7) is installed on the heat lid (3), and the heat lid (3) is supported in the guiding by the rolling member (7) Face (22), and acted along the guide surface (22) by the rolling member (7).
7. the hot lid elevating mechanism of PCR instrument according to claim 6, which is characterized in that further include position sensor, institute's rheme Set position of the sensor for monitoring the heat lid (3).
8. the hot lid elevating mechanism of PCR instrument according to claim 7, which is characterized in that the position sensor is photoelectric transfer Sensor (8), including the transmitter (81) and receiver (82) that are oppositely arranged, the two are mounted on the holder (1);
The photoelectric sensor (8) further includes the photoelectricity catch (83) for being installed on the heat lid (3), photoelectricity catch (83) energy Enough to synchronize displacement with the heat lid (3), the photoelectricity catch (83) coordinates the receiver (82), the transmitter (81) The position of the heat lid (3) can be monitored.
9. the hot lid elevating mechanism of PCR instrument according to claim 6, which is characterized in that further include bottom plate (9), the holder (1) it is fixed on the bottom plate (9), the pull module (2) is slidably connected to the bottom plate (9).
10. a kind of PCR instrument, including heat lid (3), which is characterized in that the heat lid (3) has any one of claim 1-9 institutes The hot lid elevating mechanism stated.
CN201810614004.7A 2018-06-14 2018-06-14 A kind of PCR instrument and its hot lid elevating mechanism Pending CN108728521A (en)

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Cited By (4)

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WO2022001990A1 (en) * 2020-06-30 2022-01-06 利多(香港)有限公司 Internal fixing device for apparatus in transport mode, apparatus comprising internal fixing device, and method for reducing damage to apparatus during transport
WO2022156754A1 (en) * 2021-01-22 2022-07-28 上海思路迪生物医学科技有限公司 Flipping displacement full-sealing hot lid system and driving method
WO2022257802A1 (en) * 2021-06-09 2022-12-15 圣湘生物科技股份有限公司 Cap heating device and nucleic acid detection apparatus
CN115637224A (en) * 2022-12-23 2023-01-24 鲲鹏基因(北京)科技有限责任公司 PCR instrument

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Application publication date: 20181102