CN108721783A - A kind of deep transcranial magnetic stimulation adjusts and support device and its system - Google Patents

A kind of deep transcranial magnetic stimulation adjusts and support device and its system Download PDF

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Publication number
CN108721783A
CN108721783A CN201810710655.6A CN201810710655A CN108721783A CN 108721783 A CN108721783 A CN 108721783A CN 201810710655 A CN201810710655 A CN 201810710655A CN 108721783 A CN108721783 A CN 108721783A
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support
circular coil
coil
magnetic stimulation
deep
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逯迈
董绪伟
潘强强
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Lanzhou Jiaotong University
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Lanzhou Jiaotong University
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N2/00Magnetotherapy
    • A61N2/004Magnetotherapy specially adapted for a specific therapy
    • A61N2/006Magnetotherapy specially adapted for a specific therapy for magnetic stimulation of nerve tissue
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N2/00Magnetotherapy
    • A61N2/02Magnetotherapy using magnetic fields produced by coils, including single turn loops or electromagnets

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  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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  • Life Sciences & Earth Sciences (AREA)
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  • General Health & Medical Sciences (AREA)
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Abstract

The present invention provides a kind of adjusting of deep transcranial magnetic stimulation and support devices and its system, are related to Neural stem cell technical field.The device includes:Deep cerebral magnetic stimulation coil component, support component.This component includes the first circular coil, the second circular coil and third circular coil, first circular coil acts on the crown position of human body head, third circular coil acts on the place between the eyebrows position of human body head, and the second circular coil acts on crown position to any position between place between the eyebrows position;First support bar, second support bar and the third supporting rod that support component has support housing and connect respectively with above-mentioned coil, first support bar, second support bar, third supporting rod can be relatively close or far from support housings.The device forms different location of the coil relative to human brain by adjusting, while realization stimulates brain tissue deep regional, can reach the high intensity stimulation for avoiding or mitigating to shallow-layer brain tissue, mitigate the risk of Clinical practice Neural stem cell technology.

Description

A kind of deep transcranial magnetic stimulation adjusts and support device and its system
Technical field
The present invention relates to Neural stem cell technical fields, and dress is adjusted and supported in particular to a kind of deep transcranial magnetic stimulation It sets and its system.
Background technology
Include with the influence of the factors such as the psychological pressure of social senilization and getting worse, in world wide depression, Parkinson's disease, senile dementia, epilepsy etc. and the extremely relevant nerve of neural circuit and the quantity of psychosis patient are anxious Increase severely and adds.
It is shown according to World Health Organization's data, there are about 900,000 patients with depression to die of suicide in the world every year.Again with European Union For, according to incompletely statistics, the expense for the treatment of Parkinson's disease in 2010 is up to 13,900,000,000 Euros.Thus heavy society is brought Burden and financial burden.Although certain curative effect is achieved for these nerves and psychosis, previous drug therapy, But Long-term taking medicine can generate the adverse reaction of drug resistance and drug, can aggravate the state of an illness instead.
Transcranial magnetic stimulation (Transcranial Magnetic Stimulation, TMS) technology by Barker teach in It proposes first within 1985, in recent years, as a kind of painless and noninvasive detection and treatment technology having developed rapidly, mainly Applied to cranial nerve stimulating technology.Different with wound and danger caused by tradition electro photoluminescence, transcranial magnetic stimulation passes through electromagnetism The mode of induction stimulates neuron, therefore only small electric current flows through scalp and skull, severe pain is not will produce, substantially without discomfort Sense.In view of noninvasive, the painless and Noninvasive of TMS technologies, TMS technologies have been widely used for treatment depression, schizophrenia In the rehabilitation of the equal ataxias disease such as mental diseases and Parkinson, epilepsy.
Pulse since Neural stem cell technology is most, dipulse, multi-pulse system are gradually developed to, until in recent years Deep transcranial magnetic stimulation technology is increasingly becoming the major tasks of numerous scholars' research.Especially not only to realize the same of deep stimulation When, and it is the hot spot place studied at present that can reduce to the stimulation that shallow-layer brain tissue is especially non-focal area.
The deep cerebral magnetic stimulation coil being had been reported that in document at present mainly has bipyramid coil, H coils etc..Biconial coil Similar with 8 traditional font coils, it can generate larger electric field strength, and can stimulate the area of human brain 3-4cm depth Domain.H coils can equally produce larger stimulus intensity, but stimulate depth that can reach the depth of 5-7cm, this is for deep Have been able to reach enough stimulation depth for transcranial magnetic stimulation technology, but this two classes deep magnetic stimulating coil can reach While stimulating human deep tissue, human brain shallow layer tissue is also inevitably stimulated, and will produce to make to be stimulated object Certain sense of discomfort more likely leads to accident because of will appear some complication to the stimulation of shallow-layer brain area.This is to being pierced It is with security risk to swash for person.Shallow-layer brain tissue is also pierced in view of while carrying out deep-brain stimulation Swash, this is the case where we do not expect to occur, so this is also to limit both coils to fail in the extensive use in clinic The main reason for, hinder the progress of deep transcranial magnetic stimulation technology.
Invention content
It is adjusted the purpose of the present invention is to provide a kind of deep transcranial magnetic stimulation and support device, this kind of device can pass through Adjusting different location of the composition coil relative to human brain can reach and to the greatest extent may be used while realization stimulates brain tissue deep regional It is avoided that or reduces the high intensity stimulation to shallow-layer brain tissue.The risk of Clinical practice deep transcranial magnetic stimulation technology is alleviated, New treatment means are provided for spirit and patient with nervous system disease.
Another object of the present invention is to provide a kind of deeps to stimulate through cranium and fill through cranium stimulating system, including above-mentioned deep It sets.Therefore, which can be made up of different location of the coil relative to human brain adjusting, realize and pierced to brain tissue deep regional While swashing, the high intensity stimulation for avoiding or mitigating as far as possible to shallow-layer brain tissue can be reached.Alleviate Clinical practice deep The risk of transcranial magnetic stimulation technology provides new treatment means for spirit and patient with nervous system disease.
The invention is realized in this way:
A kind of deep transcranial magnetic stimulation adjusts and support device, including:
Deep cerebral magnetic stimulation coil component, deep cerebral magnetic stimulation coil component include that sequentially coaxially line is set from top to bottom The first circular coil, the second circular coil and the third circular coil set, and the first circular coil is for acting on human body head The crown position in portion, third circular coil are used to act on the place between the eyebrows position of human body head, and the second circular coil is for acting on Crown position to any position between place between the eyebrows position;
Support component, support component have support housing and respectively with the first circular coil, the second circular coil, third First support bar, second support bar and the third supporting rod of circular coil connection, first support bar, second support bar, third Supporting rod can be relatively close or far from support housing;
Wherein, when first support bar, second support bar and third supporting rod are relatively close or when far from support housing, the One circular coil, the relative position of the second circular coil and third circular coil in the vertical direction are adjustable.
Further, in the preferred embodiment, first support bar includes the first support of Relative vertical setting With the first strut, first support one end is connected with the first circular coil, and the other end is connected with the first strut, and the first strut is used for band Dynamic first support and the first circular coil are relatively close or far from support housing;
Second support bar includes the second support and the second strut of Relative vertical setting, and second support one end is round with second Coil is connected, and the other end is connected with the second strut, and the second strut is for driving second support and the second circular coil to lean on relatively Close or remote from support housing;
Third supporting rod includes the third holder and third strut of Relative vertical setting, and third holder one end is round with third Coil is connected, and the other end is connected with third strut, and third strut is for driving third holder and third circular coil to lean on relatively Close or remote from support housing.
Further, in the preferred embodiment, the inner wall of the first strut, the second strut and third strut is equal It is provided with the straight slot for placing conducting wire, conducting wire is respectively used to the first circular coil of connection, the second circular coil or third circle Shape coil.
Further, in the preferred embodiment, deep transcranial magnetic stimulation is adjusted and support device further includes point First driving means, the second driving device and the third driving not connect with first support, second support and third holder Device, first driving means are for driving first support closer or far from support housing, and the second driving device is for driving second Holder is closer or far from support housing, and third driving device is for driving third holder closer or far from support housing.
Further, in the preferred embodiment, first driving means include the first driving motor, are driven with first The first gear and the first rack, the first rack of dynamic motor drive connection are engaged with first gear, when first gear is past default Direction rotate when can drive rack to vertical direction move, to drive first support closer or far from support housing.
Further, in the preferred embodiment, the second driving device includes the second driving motor, is driven with second The second gear and the second rack, the second rack of dynamic motor drive connection are engaged with second gear, when second gear is past default Direction rotate when can drive rack to vertical direction move, to drive second support closer or far from support housing.
Further, in the preferred embodiment, third driving device includes third driving motor, is driven with third The third gear and third rack, third rack of dynamic motor drive connection are engaged with third gear, when third gear is past default Direction rotate when can drive rack to vertical direction move, to drive third holder closer or far from support housing.
Further, in the preferred embodiment, the first driving motor, the second driving motor and third driving Motor is stepper motor.
Further, in the preferred embodiment, deep transcranial magnetic stimulation is adjusted and support device further includes setting The pedestal being placed in below support housing plays the role of stablizing entire holder.
A kind of deep transcranial magnetic stimulation system, including above-mentioned deep transcranial magnetic stimulation adjusts and support device.
The advantageous effect of said program:
The present invention provides a kind of adjusting of deep transcranial magnetic stimulation and support devices, including deep cerebral magnetic stimulation coil group Part and support component.Wherein, cerebral magnetic stimulation coil component in deep includes that sequentially coaxially the first of line setting is justified from top to bottom Shape coil, the second circular coil and third circular coil, and the first circular coil is used to act on the crown position of human body head It sets, third circular coil is used to act on the place between the eyebrows position of human body head, and the second circular coil is for acting on crown position extremely Any position between place between the eyebrows position.It is located at the circular coil for being same as axis as stimulating coil by three.It is obstructed by adjusting The height of coil can achieve the purpose that stimulate different depth region.Especially by pole while stimulating human deep tissue Stimulation of the decrease of big degree for shallow region brain tissue, to reduce the sense of discomfort of clinical risk and stimulated person.Meanwhile Support component there is support housing and connect respectively with the first circular coil, the second circular coil, third circular coil the One supporting rod, second support bar and third supporting rod, first support bar, second support bar, third supporting rod opposite can lean on Close or remote from support housing.When first support bar, second support bar and third supporting rod are relatively close or far from support housing When, the first circular coil, the relative position of the second circular coil and third circular coil in the vertical direction are adjustable.First The setting of supporting rod, second support bar and third supporting rod can effectively adjust the first circular coil, the second circular coil And the relative position of third circular coil, to achieve the purpose that stimulate different depth region.
The deep of offer stimulates adjusting and support system through cranium, including above-mentioned deep is through cranium stimulating apparatus.Therefore, this is System can be made up of different location of the coil relative to human brain adjusting can while realization stimulates brain tissue deep regional To reach the high intensity stimulation for avoiding or mitigating to shallow-layer brain tissue as far as possible.Alleviate Clinical practice deep transcranial magnetic stimulation skill The risk of art provides new treatment means for spirit and patient with nervous system disease.
Description of the drawings
In order to illustrate the technical solution of the embodiments of the present invention more clearly, below will be to needed in the embodiment attached Figure is briefly described, it should be understood that the following drawings illustrates only certain embodiments of the present invention, therefore is not construed as pair The restriction of range for those of ordinary skill in the art without creative efforts, can also be according to this A little attached drawings obtain other relevant attached drawings.
Fig. 1 is the structural schematic diagram of deep transcranial magnetic stimulation adjusting and support device that the embodiment of the present invention provides;
Fig. 2 is the cross-sectional view for the circular coil that the embodiment of the present invention provides;
Fig. 3 is structural schematic diagram of the coaxial circular coil that provides of the embodiment of the present invention when being treated;
Fig. 4 is the cross-sectional view for the holder that the embodiment of the present invention provides;
Fig. 5 is the structural schematic diagram for the strut that the embodiment of the present invention provides;
Fig. 6 is that the deep transcranial magnetic stimulation that the embodiment of the present invention provides is adjusted and the drive mechanism of support device is illustrated Figure.
Icon:The deeps 100- transcranial magnetic stimulation adjusts and support device;The deeps 101- cerebral magnetic stimulation coil component;103- First circular coil;The second circular coils of 105-;107- third circular coils;108- coil bodies;109- support components;111- Coil case;111- first support bars;113- second support bars;115- third supporting rods;117- support housings;119- first Frame;The first struts of 121-;123- second supports;The second struts of 125-;127- third holders;129- third struts;131- first Driving device;The first driving motors of 133-;135- first gears;The first racks of 137-;The second driving devices of 139-;141- second Driving motor;143- second gears;The second racks of 145-;147- third driving devices;149- third driving motors;151- thirds Gear;153- third racks;155- pedestals;157- the first magnetic stimulating coil conducting wires;159- the second magnetic stimulating coil conducting wires;161- Third magnetic stimulating coil conducting wire;The first conductor terminals of 163-;The second conductor terminals of 165-;167- privates terminals;169- One motor terminal;The second motor terminals of 171-;173- third motor terminals;175- straight slots.
Specific implementation mode
In order to make the object, technical scheme and advantages of the embodiment of the invention clearer, below in conjunction with the embodiment of the present invention In attached drawing, technical scheme in the embodiment of the invention is clearly and completely described, it is clear that described embodiment is A part of the embodiment of the present invention, instead of all the embodiments.The present invention being usually described and illustrated herein in the accompanying drawings is implemented The component of example can be arranged and be designed with a variety of different configurations.Therefore, below to the reality of the present invention provided in the accompanying drawings The detailed description for applying example is not intended to limit the range of claimed invention, but is merely representative of the selected implementation of the present invention Example.Based on the embodiments of the present invention, those of ordinary skill in the art are obtained without creative efforts Every other embodiment, shall fall within the protection scope of the present invention.
It should be noted that:Similar label and letter indicate similar terms in following attached drawing, therefore, once a certain Xiang Yi It is defined, then it further need not be defined and explained in subsequent attached drawing in a attached drawing.
In the description of the embodiment of the present invention, it should be noted that term "center", "upper", "lower", "left", "right", The orientation or positional relationship of the instructions such as "vertical", "horizontal", "inner", "outside" is to be based on the orientation or positional relationship shown in the drawings, Either the invention product using when the orientation or positional relationship usually put, be merely for convenience of the description present invention and simplification retouched It states, does not indicate or imply the indicated device or element must have a particular orientation, with specific azimuth configuration and operation, Therefore it is not considered as limiting the invention.In addition, term " first ", " second ", " third " etc. are only used for distinguishing description, and It should not be understood as indicating or implying relative importance.
In the description of the embodiment of the present invention, it is also necessary to which explanation is unless specifically defined or limited otherwise, term " setting ", " installation ", " connected ", " connection " shall be understood in a broad sense, and can also be detachably to connect for example, it may be being fixedly connected It connects, or is integrally connected;It can be mechanical connection, can also be electrical connection;It can be directly connected, intermediate matchmaker can also be passed through Jie is indirectly connected, and can be the connection inside two elements.It for the ordinary skill in the art, can be with concrete condition Understand the concrete meaning of above-mentioned term in the present invention.
In the present invention unless specifically defined or limited otherwise, fisrt feature can be on or below second feature Be in direct contact including the first and second features, can also include the first and second features not be in direct contact but by them it Between other characterisation contact.Moreover, fisrt feature is on second feature, top and above include fisrt feature second spy Right over sign and oblique upper, or be merely representative of fisrt feature level height and be higher than second feature.Fisrt feature second feature it Under, lower section and fisrt feature included below are immediately below second feature and obliquely downward, or be merely representative of fisrt feature level height Less than second feature.
Fig. 1 is the structural schematic diagram of deep transcranial magnetic stimulation provided in this embodiment adjusting and support device 100.It please refers to Fig. 1 present embodiments provides a kind of deep transcranial magnetic stimulation and adjusts and support device 100, including:Deep cerebral magnetic stimulation coil Component 101 and support component 109, support component 109 are used to support deep cerebral magnetic stimulation coil component 101.
Fig. 2 is the cross-sectional view of circular coil provided in this embodiment, and Fig. 3 is coaxial circles provided in this embodiment Structural schematic diagram of the shape coil when being treated.It please refers to Fig.1 to Fig.3, in the present embodiment, deep cerebral magnetic stimulation coil Component 101 includes that the first circular coil 103, the second circular coil 105 and the third of sequentially coaxially line setting from top to bottom are justified Shape coil 107, and the first circular coil 103 is used to act on the crown position of human body head, third circular coil 107 is for making For the place between the eyebrows position of human body head, the second circular coil 105 is for acting on crown position to arbitrary between place between the eyebrows position Position.It is located at the circular coil for being same as axis as stimulating coil by three.By adjusting the height of obstructed coil, can reach Stimulate the purpose in different depth region.Especially while stimulating human deep tissue by the decrease of high degree for shallow-layer The stimulation of region brain tissue, to reduce the sense of discomfort of clinical risk and stimulated person.Meanwhile support component 109 has support Shell 117 and connect respectively with the first circular coil 103, the second circular coil 105, third circular coil 107 first Strut 111, second support bar 113 and third supporting rod 115, first support bar 111, second support bar 113, third supporting rod 115 can be relatively close or far from support housing 117.When first support bar 111, second support bar 113 and third supporting rod When 115 relatively close or separate support housing 117, the first circular coil 103, the second circular coil 105 and third round wire The relative position of circle 107 in the vertical direction is adjustable.First support bar 111, second support bar 113 and third supporting rod 115 setting can effectively adjust the phase of the first circular coil 103, the second circular coil 105 and third circular coil 107 To position, to achieve the purpose that stimulate different depth region.
Wherein, referring to Fig. 2, the first circular coil 103, the second circular coil 105 and third circular coil 107 Include coil body 108 and coil case 111, and coil case 111 is wrapped in 108 outside of coil body.
Simultaneously, it should be noted that in the present embodiment, the first circular coil 103, the second circular coil 105 and The inductance value of three circular coils 107 can by 5uH to 150uH consecutive variations and can be directed to different stimulated brain area and stimulation require carry out It replaces and uses.Flowing through stimulated current in first circular coil 103, the second circular coil 105 and third circular coil 107 can root It is arbitrarily adjusted according to external capacitor charging and discharging circuit so that the deep transcranial magnetic stimulation adjusts and support device 100 can be used In pulse, dipulse and multiple-pulse.
Fig. 4 is the cross-sectional view of holder provided in this embodiment;Fig. 5 is the structure of strut provided in this embodiment Schematic diagram.It please refers to Fig.1, Fig. 4 and Fig. 5, in the present embodiment, first support bar 111 includes the first of Relative vertical setting Holder 119 and the first strut 121,119 one end of first support are connected with the first circular coil 103, the other end and the first strut 121 It is connected, the first strut 121 is for driving 103 relatively close or separate support housing of first support 119 and the first circular coil 117;Second support bar 113 includes second support 123 and the second strut 125 of Relative vertical setting, 123 one end of second support and Second circular coil 105 be connected, the other end is connected with the second strut 125, the second strut 125 be used for drive second support 123 with And 105 relatively close or separate support housing 117 of the second circular coil;Third supporting rod 115 includes the of Relative vertical setting Three holders 127 and third strut 129,127 one end of third holder are connected with third circular coil 107, the other end and third strut 129 are connected, and third strut 129 is used to drive third holder 127 and third circular coil 107 relatively close or outer far from support Shell 117.The setting of first strut 121, the second strut 125 and third strut 129 is used to adjust the first circular coil 103, the relative position between the second circular coil 105 and third circular coil 107.First support 119, second support 123 And the setting of third holder 127 for it is easy to support and drive the first circular coil 103, the second circular coil 105 and The movement of third circular coil 107.
Meanwhile as a preferred option, in the present embodiment, the first strut 121, the second strut 125 and third strut 129 inner wall is both provided with the straight slot 175 for placing conducting wire, and conducting wire is respectively used to connection the first circular coil 103, second circle Shape coil 105 or third circular coil 107.The setting of conducting wire can be that coil is powered, and be provided for subsequent operation enough It ensures.
Fig. 6 is the drive mechanism schematic diagram of deep transcranial magnetic stimulation provided in this embodiment adjusting and support device 100.Please Refering to fig. 1 to Fig. 6, in the present embodiment, deep transcranial magnetic stimulation adjust and support device 100 further include respectively with first support 119, first driving means 131, the second driving device 139 and the third that second support 123 and third holder 127 connect are driven Dynamic device 147, first driving means 131 are for driving first support 119 closer or far from support housing 117, the second driving dress 139 are set for driving second support 123 closer or far from support housing 117, third driving device 147 is for driving third holder 127 closer or far from support housing 117.
Wherein, first driving means 131 include the first driving motor 133, be sequentially connected with the first driving motor 133 the One gear 135 and the first rack 137, the first rack 137 are engaged with first gear 135, when first gear 135 is toward preset direction When rotation can drive rack to vertical direction move, to drive first support 119 closer or far from support housing 117.Second Driving device 139 includes the second driving motor 141, the second gear 143 and second with the drive connection of the second driving motor 141 Rack 145, the second rack 145 are engaged with second gear 143, can drive rack when second gear 143 is rotated toward preset direction It is moved to vertical direction, to drive second support 123 closer or far from support housing 117.Third driving device 147 includes the Three driving motors 149, the third gear 151 being sequentially connected with third driving motor 149 and third rack 153, third rack 153 engage with third gear 151, when third gear 151 is rotated toward preset direction can drive rack to vertical direction move, from And drive third holder 127 closer or far from support housing 117.The branch that circular coil passes through coil brace and movable belt rack Bar is connected.Strut with rack can move up and down that corresponding circular coil is driven to move up and down, and pass through adjusting gear rack branch The height of bar can be to magnetic stimulating coil relative to human brain position height be adjusted, to facilitate, to adapt to different heights different The human body of head dummy.Meanwhile in the present embodiment, the strut that controls to adjust coil height be by way of rack and pinion coupling into Row is adjusted.By the uniform rotation of gear, the circular motion of gear is converted to the uniform motion of rack vertical direction, to reach To the purpose of regulating winding height.
Wherein, it should be noted that in the present embodiment, deep transcranial magnetic stimulation is adjusted and support device 100 further includes The first motor terminal being electrically connected with the first driving motor 133, the second driving motor 141 and third driving motor 149 169, the second motor terminal 171 and third motor terminal 173.First motor terminal 169, the second motor terminal 171 and Three motor terminals 173 are for connecting motor, in order to control signal and power supply.
In detail, referring to Fig. 6, in the present embodiment, deep transcranial magnetic stimulation is adjusted and support device 100 is also wrapped Include the first magnetic stimulating coil conducting wire 157, the second magnetic stimulating coil conducting wire 159, third magnetic stimulating coil being respectively communicated with conducting wire Conducting wire 161.Also, the first magnetic stimulating coil conducting wire 157, the second magnetic stimulating coil conducting wire 159, third magnetic stimulating coil conducting wire 161 are electrically connected respectively at the first conductor terminal 163, the second conductor terminal 165 and privates terminal 167.
As a preferred option, in the present embodiment, the first driving motor 133, the second driving motor 141 and third are driven Dynamic motor 149 is stepper motor.Using the control mode of high-precision stepper motor, pass through high-precision step motor control gear Rotation to drive the movement of stimulating coil, the displacement distance of stimulating coil is continuously adjustable.
It is further preferred that in the present embodiment, referring to Fig. 1, deep transcranial magnetic stimulation adjusts and support device 100 further include the pedestal 155 for being set to 117 lower section of support housing.
The embodiments of the present invention also provide a kind of deep transcranial magnetic stimulation systems, including above-mentioned deep transcranial magnetic stimulation Adjusting and support device 100.
In conclusion the deep transcranial magnetic stimulation that the embodiment of the present invention provides adjusts and support device 100 and system Working principle and beneficial effect is:
The first circular coil 103, the second circular coil 105 and third circular coil 107 lead to respectively in use First support bar 111, second support bar 113 and third supporting rod 115 is crossed to connect.First support bar 111, second support bar 113 and third supporting rod 115 be hollow-core construction, centre can wear metallic conductor with circle magnetic stimulating coil be connected.First support Bar 111, second support bar 113 and 115 inner wall of third supporting rod have straight slot 175 be used for install connection the first circular coil 103, The conducting wire of second circular coil 105 and third circular coil 107, while there have this straight slot 175 that can guarantee to be smooth Adjust the movement of strut.The first rack 137, the second rack 145 and third rack 153 are close smooth between outer wall simultaneously It is connected, this makes it possible to ensure stability and fluency of the rack during moving up and down.First rack 137, the second rack 145 and third rack 153 and gear and high-precision stepper motor below the device first gear 135, the second tooth Wheel 143 and third gear 151 are of coupled connections, and convert the circular motion of stepper motor to the linear motion up and down of rack.System Connection terminal the first conductor terminal 163, two conductor terminals, the privates terminal 167 of system bottom are used for connecting external Neural stem cell Power-supply system and round magnetic stimulating coil;First motor terminal 169, the second motor terminal 171 and third motor terminal 173 are used To connect control signal and the power supply of stepper motor.
When in use, the height by adjusting supporting rod can realize position of the circular coil relative to human brain to system. The first circular coil 103 is generally positioned over the human brain crown and is close to the crown, third circular coil 107 is typically placed at and treats The concordant position of person's place between the eyebrows, line between the first circular coil of height 103 and third circular coil 107 of the second circular coil 105 Property it is continuously adjustable.
Certain arteries and veins is each led into first circular coil 103, the second circular coil 105 and third circular coil 107 Rushing electric current can realize to human deep progress Neural stem cell, while be existed mutually in the field that different location generates according to three coils The phenomenon that offseting or enhancing is realizing that the while of stimulating human brain tissue deep regional can also weaken or offsets pair as much as possible The stimulation of human brain shallow region tissue.
In experiment or clinical application, deep transcranial magnetic stimulation can be accessed storage capacitor with coaxial circles coil group fixing device Device, the conducting by controlling high-voltage switch gear is discharged, and certain alternating impulse electromagnetic field is generated around circular coil, passes through three Superposition of the pulse electromagnetic field that coil generates in human brain is to reach the stimulation for brain deep tissue while be supported according to vector The stimulation organized to shallow region can be reduced or disappeared as far as possible by the theory that disappears.
To sum up, deep transcranial magnetic stimulation is adjusted and support device 100 is adjusted with coaxial circles coil group and fixing device, is realized Superposition of the field generated by three circular coils in human brain tissue, by realizing the adjusting of coil position to different depths Degree, the deep Neural stem cell function of Different brain region.
The deep of offer is through cranium stimulating system, including above-mentioned deep is through cranium stimulating apparatus.Therefore, which can pass through Adjusting different location of the composition coil relative to human brain can reach and to the greatest extent may be used while realization stimulates brain tissue deep regional It is avoided that or mitigates the high intensity stimulation to shallow-layer brain tissue.The risk of Clinical practice deep transcranial magnetic stimulation technology is alleviated, New treatment means are provided for spirit and patient with nervous system disease.
The foregoing is only a preferred embodiment of the present invention, is not intended to restrict the invention, for the skill of this field For art personnel, the invention may be variously modified and varied.All within the spirits and principles of the present invention, any made by repair Change, equivalent replacement, improvement etc., should all be included in the protection scope of the present invention.

Claims (10)

1. a kind of deep transcranial magnetic stimulation adjusts and support device, which is characterized in that including:
Deep cerebral magnetic stimulation coil component, the deep cerebral magnetic stimulation coil component include that sequentially coaxially line is set from top to bottom The first circular coil, the second circular coil and the third circular coil set, and first circular coil is for acting on people The crown position on body head, the third circular coil are used to act on the place between the eyebrows position of the human body head, second circle Shape coil is for acting on crown position to any position between place between the eyebrows position;
Support component, the support component have support housing and respectively with first circular coil, described second round First support bar, second support bar and the third supporting rod that coil, the third circular coil connect, first support Bar, the second support bar, the third supporting rod can be relatively close or far from the support housings;
Wherein, when the first support bar, the second support bar and the third supporting rod are relatively close or separate described When support housing, first circular coil, second circular coil and the third circular coil are in the vertical direction Relative position it is adjustable.
2. deep transcranial magnetic stimulation according to claim 1 adjusts and support device, it is characterised in that:
The first support bar includes first support and the first strut of Relative vertical setting, described first support one end with it is described First circular coil be connected, the other end is connected with first strut, first strut be used for drive the first support with And first circular coil is relatively close or far from the support housing;
The second support bar includes second support and the second strut of Relative vertical setting, described second support one end with it is described Second circular coil be connected, the other end is connected with second strut, second strut be used for drive the second support with And second circular coil is relatively close or far from the support housing;
The third supporting rod includes third holder and the third strut of Relative vertical setting, third holder one end with it is described Third circular coil be connected, the other end is connected with the third strut, the third strut be used for drive the third holder with And the third circular coil is relatively close or far from the support housing.
3. deep transcranial magnetic stimulation according to claim 2 adjusts and support device, it is characterised in that:
The inner wall of first strut, second strut and the third strut is both provided with for placing the logical of conducting wire Slot, the conducting wire are respectively used to connect first circular coil, second circular coil or the third circular coil.
4. deep transcranial magnetic stimulation according to claim 2 adjusts and support device, it is characterised in that:
The deep transcranial magnetic stimulation adjust and support device further include respectively with the first support, the second support and First driving means, the second driving device and the third driving device of the third holder connection, the first driving means For driving the first support closer or far from the support housing, second driving device is for driving described second Frame is closer or far from the support housing, and the third driving device is for driving the third holder closer or far from the branch Support shell.
5. deep transcranial magnetic stimulation according to claim 4 adjusts and support device, it is characterised in that:
The first driving means include the first driving motor, with first driving motor be sequentially connected first gear and First rack, first rack are engaged with the first gear, can be driven when the first gear is rotated toward preset direction The rack is moved to vertical direction, to drive the first support closer or far from the support housing.
6. deep transcranial magnetic stimulation according to claim 5 adjusts and support device, it is characterised in that:
Second driving device include the second driving motor, with second driving motor be sequentially connected second gear and Second rack, second rack are engaged with the second gear, can be driven when the second gear is rotated toward preset direction The rack is moved to vertical direction, to drive the second support closer or far from the support housing.
7. deep transcranial magnetic stimulation according to claim 6 adjusts and support device, it is characterised in that:
The third driving device include third driving motor, with the third driving motor be sequentially connected third gear and Third rack, the third rack are engaged with the third gear, can be driven when the third gear is rotated toward preset direction The rack is moved to vertical direction, to drive the third holder closer or far from the support housing.
8. deep transcranial magnetic stimulation according to claim 7 adjusts and support device, it is characterised in that:
First driving motor, second driving motor and the third driving motor are stepper motor.
9. deep transcranial magnetic stimulation according to any one of claim 1 to 8 adjusts and support device, it is characterised in that:
The deep transcranial magnetic stimulation is adjusted and support device further includes the pedestal being set to below the support housing.
10. a kind of deep transcranial magnetic stimulation adjusts and support system, which is characterized in that including any one of claim 1 to 9 institute The deep transcranial magnetic stimulation stated adjusts and support device.
CN201810710655.6A 2018-07-02 2018-07-02 A kind of deep transcranial magnetic stimulation adjusts and support device and its system Pending CN108721783A (en)

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CN102462892A (en) * 2010-11-09 2012-05-23 首都医科大学附属北京安定医院 Head-mounted position adjustable transcranial magnetic stimulation device
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