CN108721497A - A kind of Chinese drugs agentia for treating nasosinusitis - Google Patents

A kind of Chinese drugs agentia for treating nasosinusitis Download PDF

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CN108721497A
CN108721497A CN201710279415.0A CN201710279415A CN108721497A CN 108721497 A CN108721497 A CN 108721497A CN 201710279415 A CN201710279415 A CN 201710279415A CN 108721497 A CN108721497 A CN 108721497A
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drugs agentia
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王淑英
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    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
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    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/26—Aristolochiaceae (Birthwort family), e.g. heartleaf
    • A61K36/268—Asarum (wild ginger)
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Abstract

The present invention provides a kind of Chinese drugs agentia for treating nasosinusitis, and ingredient includes：Radix Notoginseng, herb of Ajuga pantantha Hand.-Mazz., five leaf grass, tendrilleaf solomonseal rhizome, Bai Yeju, big rattan root, Chinese yam rhizome, the flower bud of lily magnolia, felwort, the root of Dahurain angelica, asarum, the windproof, achene of Siberian cocklebur, it is characterised in that：The medicament made of the bulk pharmaceutical chemicals of following parts by weight, 150~250 parts of Radix Notoginseng, 60~90 parts of herb of Ajuga pantantha Hand.-Mazz., 20~40 parts of five leaf grass, 20~50 parts of tendrilleaf solomonseal rhizome, 10~30 parts of Bai Yeju, 40~60 parts of big rattan root, 60~80 parts of Chinese yam rhizome, 3~9 parts of the flower bud of lily magnolia, 8~15 parts of felwort, 2~5 parts of the root of Dahurain angelica, 2~5 parts of asarum, 1~2 part windproof, 1~5 part of the achene of Siberian cocklebur.Administration time of the present invention is short, therapeutic effect is good and stablizes, and is not recurred after drug withdrawal, especially has good therapeutic effect to nasosinusitis.

Description

A kind of Chinese drugs agentia for treating nasosinusitis
Technical field
The present invention relates to Chinese medicine preparation technical field, specially a kind of Chinese drugs agentia for treating nasosinusitis.
Background technology
Rhinitis (Rhinitis) is the inflammation of nasal membrane and submucous tissue, shows as congested or oedema.Patient passes through It often has a stuffy nose, watery nasal discharge, rhiocnesmus, throat is uncomfortable, the symptoms such as sneeze, cough.It is because of acute or chronic schneiderian membrane such as disease Poison, germ infection or the effect of stimulant are damaged and cause.Rhinitis not only influences nose, throat and eyes, can also influence sleep, Hearing, or even headache, dizzy, loss of appetite, easily tired, failure of memory etc..When influencing the physiological function of nasal cavity, it may appear that Respiratory disorder causes lowered blood oxygen, influences function and the metabolism of other tissues and organ.Rhinitis etiology and pathogenesis is mostly to experience wind-heat Or chill, enter innerization heat, the turbid tears blocking nose key of heat toxin forms.Chronic person is mostly because of spleen and lung weakness, insufficiency of lung-QI,deficiency of lung-QI to weakened defensive QI, easily Feel exopathogen.Spleen deficiency then be detained by transformation failure of spleen, phlegm wet, is stranded knot nose key, and contamination sinus mucosa forms nasosinusitis.Therefore rhinitis chronic should be clear Lung benefit spleen.Rhinitis is primarily due to Lung Qi deficiency, instability of surface, and chill is taken advantage of a weak point, and criminal and nose key, pathogen conflicting with vital QI, lung qi is obstructed, Tianjin Liquid stops gathering, sneeze runny nose；Enriching for lung qi, depends on the defeated cloth of temper, Spleen-Qi Deficiency then Lung Qi deficiency, and the root of gas is in kidney, kidney deficiency It then takes the photograph and receives inability, gas does not return member, yang-energy to be easy to dissipate, invade and cause a disease in ailment said due to cold or exposure.Therefore, it is wind-cold affecting lung that early stage is often dialectical Or the real examples such as lung channel intrinsic heat, with disease progression, different degrees of deficient of internal organs is often dialectical for Lung Qi deficiency or lung spleen or lung kidney Two is empty, even three dirty all void of lung spleen kidney.Nearly ninety percent nasopharyngeal carcinoma is caused by rhinitis obstinate.Some patients with rhinitis's concha nasalis inferior fertilizer Greatly, oxygen is insufficient when sleep, serious to cause cerebral infarction, hypertension, heart attack etc., or even sudden death.The symptom of rhinitis It is caused by excessively high histamine.And lead to that histamine increases be the secretion of these positions liquid.
Currently, the drug for the treatment of rhinitis divides Western medicine, Chinese medicine, Chinese patent drug, nasal drop etc., it is not drug costliness, exactly takes It is inconvenient, it is important to which that palliative, the more, Relapse rate is unbroken by patient suffering, influences studying and living.
Invention content
Technical problem solved by the invention is to provide a kind of Chinese drugs agentia for treating nasosinusitis, to solve above-mentioned background The problems in technology.
Technical problem solved by the invention is realized using following technical scheme：A kind of Chinese medicine medicine for treating nasosinusitis Agent, the medicament made of the bulk pharmaceutical chemicals of following parts by weight,
150~250 parts of Radix Notoginseng, 60~90 parts of herb of Ajuga pantantha Hand.-Mazz., 20~40 parts of five leaf grass, 20~50 parts of tendrilleaf solomonseal rhizome, Bai Yeju 10~30 Part, 40~60 parts of big rattan root, 60~80 parts of Chinese yam rhizome, 3~9 parts of the flower bud of lily magnolia, 8~15 parts of felwort, 2~5 parts of the root of Dahurain angelica, asarum 2~5 Part, 1~2 part windproof, 1~5 part of the achene of Siberian cocklebur.
The preferred weight number of each component is：
210 parts of Radix Notoginseng, 80 parts of herb of Ajuga pantantha Hand.-Mazz., 35 parts of five leaves grass, 30 parts of tendrilleaf solomonseal rhizome, 25 parts of Bai Yeju, 55 parts of big rattan root, Chinese yam rhizome 65 Part, 8 parts of the flower bud of lily magnolia, 10 parts of felwort, 4 parts of the root of Dahurain angelica, 4 parts of asarum, 1 part windproof, 1 part of the achene of Siberian cocklebur.
The preferred weight number of each component is：
200 parts of Radix Notoginseng, 70 parts of herb of Ajuga pantantha Hand.-Mazz., 30 parts of five leaves grass, 35 parts of tendrilleaf solomonseal rhizome, 30 parts of Bai Yeju, 50 parts of big rattan root, Chinese yam rhizome 65 Part, 5 parts of the flower bud of lily magnolia, 8 parts of felwort, 2 parts of the root of Dahurain angelica, 2 parts of asarum, 2 parts windproof, 2 parts of the achene of Siberian cocklebur.
Bulk pharmaceutical chemicals used in the present invention can be commercially available from common Chinese shop, and specification meets national Chinese medicine standard i.e. It can.
It is a further object to provide a kind of methods preparing the present composition, include the following steps,
1）Each taste bulk pharmaceutical chemicals are weighed by parts by weight described in prescription；
2）It pulverizes after above-mentioned each taste material medicine is mixed and is put into 2500 grams of Mahuang Tang, shake up clear liquid is taken to drip later Enter in nasal cavity, the Mahuang Tang production method is：Take Herba Ephedrae, white wine by weight 5:1 ratio is impregnated 3~6 months ?.
1, pharmacology analysis：
Radix Notoginseng：Temperature；Sweet, slight bitter；Return liver, stomach；Dissipate stasis of blood hemostasis, detumescence ding-tong.For spitting blood, haematemesis, bleeding from five sense organs or subcutaneous tissue is had blood in stool, uterine bleeding, Traumatic hemorrhage, chest and abdomen shouting pain, tumbling and swelling.
Herb of Ajuga pantantha Hand.-Mazz.：Bitter；It is cold in nature；It is clearing heat and detoxicating；Cool blood detumescence, heat-clearing and detoxifying drug；Cool blood detumescence medicine, cures mainly Chronic Liver It is scorching；Urine leaching pain；Aphtha；Sore swollen toxin；Treating swelling and pain by traumatic injury.
Five leaves grass：Bitter；Micro-pungent；It is mild-natured；Channel tropism spleen；Bladder warp, dispelling wind and removing obstruction in the meridians；Promoting blood circulation；Clearing heat and promoting diuresis, dispel-wind drug；It is logical Network medicine；Heat-clearing and detoxifying drug；Cure mainly arthralgia pain due to rheumatism；Numbness；Muscles and bones is miserable；Traumatic injury；Dysentery；Sore.
Tendrilleaf solomonseal rhizome：It is bitter；It is pungent；It is clearing heat and detoxicating；Activating blood circulation and reducing swelling, heat-clearing and detoxifying drug；Activating blood circulation and reducing swelling medicine, cures mainly carbuncle furuncle poison；It is soft Tissue damage；Bee stings insect bite
Bai Yeju：Acrid flavour；It is sweet；Slight bitter；It is warm-natured, expelling wind and clearing away cold；Promoting the circulation of qi dampness removing；Removing toxicity for detumescence, dispel-wind drug；Clearing damp medicine；Qi-activating drug, Cure mainly anemofrigid cold；Cough；Arthralgia pain due to rheumatism；Let out dysentery；Hepatitis；Mastitis；Hemorrhoid；Eczema；Mange.
Big rattan root：It is sweet；It is bitter；It is flat, dispelling wind and eliminating dampness；Promoting blood circulation and stopping pain, Medicine for the treatment of rheumatism and arthritis；Blood-activating analgesic cures mainly treating rheumatic ostealgia； Bruise internal lesion caused by overexertion；Hepatitis.
Chinese yam rhizome：It is mild-natured, it is sweet in flavor, cure mainly tonifying spleen nourishing the stomach, engender liquid and benefic lung, the puckery essence of kidney tonifying.For spleen eating less, chronic diarrhea is not Only, the deficiency syndrome of the lung is breathed with cough, emission due to the kidney deficiency, under band, frequent micturition.
Herba Ephedrae：Warm-natured, acrid flavour, slight bitter, major function sweating cold dispelling are freeinged lung and relieving asthma, inducing diuresis for removing edema.For chill sense It emits, uncomfortable in chest to breath with cough, geomantic omen edema；Bronchial asthma.
The flower bud of lily magnolia：It is pungent；It is warm-natured, lung；Stomach, dispersing wind and cold；Clearing the nasal passage, diaphoretic medicine；Awaking drug；Treating rhinitis；Anemofrigid cold it Headache；Nasal obstruction；Runny nose.
Felwort：Hardship is trembled with fear.Return liver, gallbladder channel；Cure mainly heat-clearing and damp-drying drug, purging the liver of pathogenic fire courage fire.For jaundice with damp-heat pathogen, swelling of vulva pruritus vulvae, band Under, persistent erection, eczema itch, hot eyes is deaf, hypochondriac pain, bitter taste, convulsion.
The root of Dahurain angelica：It is acrid in flavour and warm in nature.It attaches to the lung and stomach meridians；Expelling wind and clearing away cold, sensible analgesic, detumescence and apocenosis, eliminating dampness stops band.
Asarum：It is pungent, warm, lung, spleen, Liver Channel, expelling wind and clearing away cold；Cough-relieving apophlegmatic；Promoting blood circulation and detoxication；Analgesic, expelling wind and clearing away cold medicine；Cough-relieving Expectorant；Promoting blood circulation and detoxication medicine；Anodyne；Cure mainly anemofrigid cold；Cough and asthma；Toothache；Heatstroke abdominal pain；Enteritis；Dysentery；Rheumatoid arthrosis aches Bitterly；Traumatic injury；Ulcerative carbuncle pyogenic infections；Snake bite.
It is windproof：Acrid flavour；It is sweet；Slightly warm in nature returns bladder；Lung；Spleen；Liver Channel expels pathogenic wind from the body surface；Expel endogenous wind to relieve convulsion；Spasmolysis；It is antipruritic, solution Medicine administered to bring out the cold；Dispel-wind drug is cured mainly and is caught cold；Headache bodily pain；Arthralgia pain due to rheumatism；Skeletal pain；Abdominal pain diarrhea；Discharging fresh blood stool；Lockjaw； Rubella itch；Sore from the beginning of.
The achene of Siberian cocklebur：Bitter；It is sweet；It is pungent；It is warm-natured；Mild toxicity cures mainly nasosinusitis；Anemofrigid headache；Arthralgia pain due to rheumatism；Rubella；Eczema；Scabies Tinea.
2, usage and dosage：
The dosage of drug of the present invention depends on the factors such as specific dosage form and age, weight, the health status of patient.It uses Guidance：Take phinamide collunarium, daily three to five times, each 2-3 drops.
Compared with public technology, there are following advantages by the present invention：Administration time of the present invention is short, therapeutic effect is good and steady It is fixed, it is not recurred after drug withdrawal, especially has good therapeutic effect to nasosinusitis.
Specific implementation mode
In order to make technological means, creation characteristic, workflow, application method reached purpose and effect of the present invention be easy to bright White to understand, below in conjunction with the embodiment of the present invention, technical scheme in the embodiment of the invention is clearly and completely described, Obviously, described embodiments are only a part of the embodiments of the present invention, instead of all the embodiments.Based in the present invention Embodiment, every other embodiment obtained by those of ordinary skill in the art without making creative efforts, all Belong to the scope of protection of the invention.
Embodiment 1
From common Chinese shop buy prescription drug, weigh 210 grams of Radix Notoginseng, 80 grams of herb of Ajuga pantantha Hand.-Mazz., five leaves grass 35 grams, 30 grams of tendrilleaf solomonseal rhizome, It is 25 grams of Bai Yeju, 55 grams of big rattan root, 65 grams of Chinese yam rhizome, 3 grams of the flower bud of lily magnolia, 8 grams of felwort, 2 grams of the root of Dahurain angelica, 2 grams of asarum, 1 gram windproof, grey 1 gram of the ears or side handles of a utensil pulverize after mixing above-mentioned each taste material medicine and are put into 2500 grams of Mahuang Tang, shake up daily three later To five times, each 2-3 drops.
Embodiment 2
From common Chinese shop buy prescription drug, weigh 200 grams of Radix Notoginseng, 70 grams of herb of Ajuga pantantha Hand.-Mazz., five leaves grass 30 grams, 35 grams of tendrilleaf solomonseal rhizome, It is 30 grams of Bai Yeju, 50 grams of big rattan root, 65 grams of Chinese yam rhizome, 4 grams of the flower bud of lily magnolia, 9 grams of felwort, 3 grams of the root of Dahurain angelica, 3 grams of asarum, 1 gram windproof, grey 2 grams of the ears or side handles of a utensil pulverize after mixing above-mentioned each taste material medicine and are put into 2500 grams of Mahuang Tang, shake up daily three later To five times, each 2-3 drops.
Embodiment 3
From common Chinese shop buy prescription drug, weigh 200 grams of Radix Notoginseng, 65 grams of herb of Ajuga pantantha Hand.-Mazz., five leaves grass 25 grams, 30 grams of tendrilleaf solomonseal rhizome, 25 grams of Bai Yeju, 50 grams of big rattan root, 65 grams of Chinese yam rhizome, 5 grams of the flower bud of lily magnolia, 10 grams of felwort, 4 grams of the root of Dahurain angelica, 4 grams of asarum, it is 2 grams windproof, 3 grams of the achene of Siberian cocklebur pulverizes after mixing above-mentioned each taste material medicine and is put into 2500 grams of Mahuang Tang, shakes up later daily Three to five times, each 2-3 drops.
Embodiment 4
From common Chinese shop buy prescription drug, weigh 200 grams of Radix Notoginseng, 60 grams of herb of Ajuga pantantha Hand.-Mazz., five leaves grass 25 grams, 35 grams of tendrilleaf solomonseal rhizome, 25 grams of Bai Yeju, 50 grams of big rattan root, 65 grams of Chinese yam rhizome, 6 grams of the flower bud of lily magnolia, 11 grams of felwort, 5 grams of the root of Dahurain angelica, 5 grams of asarum, it is 2 grams windproof, 5 grams of the achene of Siberian cocklebur pulverizes after mixing above-mentioned each taste material medicine and is put into 2500 grams of Mahuang Tang, shakes up later daily Three to five times, each 2-3 drops.
Embodiment 5
From common Chinese shop buy prescription drug, weigh 190 grams of Radix Notoginseng, 70 grams of herb of Ajuga pantantha Hand.-Mazz., five leaves grass 25 grams, 35 grams of tendrilleaf solomonseal rhizome, 30 grams of Bai Yeju, 50 grams of big rattan root, 60 grams of Chinese yam rhizome, 7 grams of the flower bud of lily magnolia, 12 grams of felwort, 5 grams of the root of Dahurain angelica, 5 grams of asarum, it is 2 grams windproof, 5 grams of the achene of Siberian cocklebur pulverizes after mixing above-mentioned each taste material medicine and is put into 2500 grams of Mahuang Tang, shakes up later daily Three to five times, each 2-3 drops.
Embodiment 6
From common Chinese shop buy prescription drug, weigh 190 grams of Radix Notoginseng, 60 grams of herb of Ajuga pantantha Hand.-Mazz., five leaves grass 30 grams, 35 grams of tendrilleaf solomonseal rhizome, 30 grams of Bai Yeju, 40 grams of big rattan root, 65 grams of Chinese yam rhizome, 8 grams of the flower bud of lily magnolia, 15 grams of felwort, 2 grams of the root of Dahurain angelica, 2 grams of asarum, it is 2 grams windproof, 1 gram of the achene of Siberian cocklebur pulverizes after mixing above-mentioned each taste material medicine and is put into 2500 grams of Mahuang Tang, shakes up later daily Three to five times, each 2-3 drops.
Model case：
Case 1
Zhang, female, 28 years old, people from Anhui suffered from more than 6 years of rhinitis chronic, and duration nasal obstruction flows dense tears.With Chinese drugs agentia of the present invention One course for the treatment of, symptom disappear, ventilate, and no headache, concha enlargement disappears, without recurrence in 3 years.
Case 2
Mr. Wang, man, 46 years old, people from Jiangsu suffered from allergic rhinitis 10 years, and clear water sample nasal mucus is flowed in early morning sneezing, and nasal membrane is grey White, hyposphresia.It fully recovers after with one course for the treatment of of Chinese drugs agentia of the present invention, no relapse in 5 years.
Case 3
Zhao so-and-so, man, 35 years old, people of Guangzhou suffered from chronic nasosinusitis 15 years.Early morning sneezing, headache, nasal membrane have rotten to the corn existing As nasal obstruction has dense tears, obstinate.Through using two courses for the treatment of of Chinese drugs agentia of the present invention, symptom to disappear, ventilation is good, and concha is swollen Big to disappear, nasal membrane repairs.
Case 4
It is high so-and-so, female, 53 years old, people from Hubei suffered from rhinitis chronic 7 years.Nasal obstruction, headache, there is forehead reflectivity distending pain, intermittent nose Plug, concha enlargement.Through using one course for the treatment of of Chinese drugs agentia of the present invention, nasal airflow is good, and headache disappears, and is not recurred in 4 years.
Case 5
Wei so-and-so, man, 48 years old, people from Hunan suffered from chronic nasosinusitis 26 years, and headache, nasal obstruction are serious, has purulence silly in nasal cavity, once punctured Processing, it is ineffective.By using two course for the treatment of posterula ventilations of Chinese drugs agentia of the present invention good, headache mitigates.Continue medication, After another course for the treatment of, symptom totally disappeared, and not recurred in 2 years.
It is proved through 500 applicable cases of clinical patients, cure rate (is fully recovered and showed up to 97:Nasal airflow is good, and headache disappears, Secretion is reduced, and concha is not loose), (the effectively performance of effective percentage 2%:Nasal airflow situation and the big situation of concha have earlier above to be changed It is kind, but completely normal not yet).
Present invention composition is simple, and pure Chinese medicine component, composition is fastidious, scientific and reasonable, has no toxic side effect, easy to use, generally One course for the treatment of can fully recover, and curative effect is fast, and good effect, efficacy stability, recurrence rate is low, can effect a radical cure a variety of noses such as rhinitis, nasosinusitis Chamber disease.
The basic principles and main features and advantages of the present invention of the present invention have been shown and described above.The technology of the industry Personnel are it should be appreciated that the present invention is not limited to the above embodiments, and the above embodiments and description only describe this The principle of invention, without departing from the spirit and scope of the present invention, various changes and improvements may be made to the invention, these changes Change and improvement all fall within the protetion scope of the claimed invention.The claimed range of the present invention by appended claims and Its equivalent thereof.

Claims (4)

1. a kind of Chinese drugs agentia for treating nasosinusitis, ingredient include：It is Radix Notoginseng, herb of Ajuga pantantha Hand.-Mazz., five leaf grass, tendrilleaf solomonseal rhizome, Bai Yeju, big Rattan root, Chinese yam rhizome, the flower bud of lily magnolia, felwort, the root of Dahurain angelica, asarum, the windproof, achene of Siberian cocklebur, it is characterised in that：By the bulk pharmaceutical chemicals of following parts by weight Manufactured medicament, 150~250 parts of Radix Notoginseng, 60~90 parts of herb of Ajuga pantantha Hand.-Mazz., 20~40 parts of five leaf grass, 20~50 parts of tendrilleaf solomonseal rhizome, Bai Yeju 10~30 parts, it is 40~60 parts of big rattan root, 60~80 parts of Chinese yam rhizome, 3~9 parts of the flower bud of lily magnolia, 8~15 parts of felwort, 2~5 parts of the root of Dahurain angelica, thin Pungent 2~5 parts, 1~2 part windproof, 1~5 part of the achene of Siberian cocklebur.
2. a kind of Chinese drugs agentia for treating nasosinusitis according to claim 1, it is characterised in that：The Chinese drugs agentia each group Point preferred weight number be：210 parts of Radix Notoginseng, 80 parts of herb of Ajuga pantantha Hand.-Mazz., 35 parts of five leaves grass, 30 parts of tendrilleaf solomonseal rhizome, 25 parts of Bai Yeju, big rattan 55 parts of root, 65 parts of Chinese yam rhizome, 8 parts of the flower bud of lily magnolia, 10 parts of felwort, 4 parts of the root of Dahurain angelica, 4 parts of asarum, 1 part windproof, 1 part of the achene of Siberian cocklebur.
3. a kind of Chinese drugs agentia for treating nasosinusitis according to claim 1, it is characterised in that：The Chinese drugs agentia each group Point preferred weight number be：200 parts of Radix Notoginseng, 70 parts of herb of Ajuga pantantha Hand.-Mazz., 30 parts of five leaves grass, 35 parts of tendrilleaf solomonseal rhizome, 30 parts of Bai Yeju, big rattan 50 parts of root, 65 parts of Chinese yam rhizome, 5 parts of the flower bud of lily magnolia, 8 parts of felwort, 2 parts of the root of Dahurain angelica, 2 parts of asarum, 2 parts windproof, 2 parts of the achene of Siberian cocklebur.
4. a kind of Chinese drugs agentia for treating nasosinusitis according to claim 1, it is characterised in that：It is prepared by the Chinese drugs agentia Method includes the following steps,
1）Each taste bulk pharmaceutical chemicals are weighed by parts by weight described in prescription；
2）It pulverizes after above-mentioned each taste material medicine is mixed and is put into 2500 grams of Mahuang Tang, shake up clear liquid is taken to drip later Enter in nasal cavity, the Mahuang Tang production method is：Take Herba Ephedrae, white wine by weight 5:1 ratio is impregnated 3~6 months ?.
CN201710279415.0A 2017-04-25 2017-04-25 A kind of Chinese drugs agentia for treating nasosinusitis Withdrawn CN108721497A (en)

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