CN108717119A - The random Quality Control loading methods based on time series of enzyme linked immunosorbent detection - Google Patents
The random Quality Control loading methods based on time series of enzyme linked immunosorbent detection Download PDFInfo
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- CN108717119A CN108717119A CN201810356966.7A CN201810356966A CN108717119A CN 108717119 A CN108717119 A CN 108717119A CN 201810356966 A CN201810356966 A CN 201810356966A CN 108717119 A CN108717119 A CN 108717119A
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/558—Immunoassay; Biospecific binding assay; Materials therefor using diffusion or migration of antigen or antibody
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
Abstract
The invention discloses the random Quality Control loading methods based on time series of enzyme linked immunosorbent detection.This method includes keeping sequence rack position and each frame placement sample, Quality Control or control site constant, according to the variation of time conditions during sample injector sample-adding, mathematical model is calculated and carries out sequence location and is replaced automatically, automatically by fixed position Quality Control inhale sample after at random to the holes elisa plate 1-88 any position, the sample application that picking is replaced by random Quality Control ultimately forms in 1-88 samples to protoplasm control fixed position comprising the unfixed sample-adding combination of quality-control product and quality-control product position.Invention introduces time serieses, using Monte Carlo EGS4 method, by the variation of time point and second, causing the variation of algorithm makes batch interior Quality Control position randomly generate, each hole position of elisa plate can be monitored by solving enzyme linked immune assay Quality Control, can discover influence of the edge effect to testing result.
Description
Technical field
The invention belongs to Bioexperiment equipment technical fields；It is related to the random matter based on time series of enzyme linked immunosorbent detection
Control loading methods.
Background technology
The used enzyme linked immunological of clinical detection antigen of hepatitis B virus antibody, c-hepatitis antibody, AIDS virus antibody at present
(ELISA) method carries out.Every batch of experiment has 80-100 test, and one weakly positive Quality Control of addition is needed to carry out the effective of monitoring test
Whether, weakly positive Quality Control detection proves that experiment is effective, does not detect, and proves to test that there are problems by the gross, is added in an experiment
Quality Control is all fixed position, and every batch of experiment has multiple hole positions, fixed Quality Control that can only be monitored to the fixed hole position tested by the gross,
All holes position that this batch experiment cannot be monitored whether there is problem, not be avoided that other holes position or experiment part due to being incubated temperature
Degree, the abnormal causes such as additional examination dosage lead to experiment, and there are problems, and then there may be the results of mistake.The present invention can be according to the time
Variation, generate different parameters, Quality Control position made to randomly generate, solving enzyme linked immune assay Quality Control can be to elisa plate
Each hole position is monitored, and can discover influence of the edge effect to testing result.
Random Quality Control at present can only be that quality-control product is manually randomly placed in the lot sample during every batch of is tested and is loaded
It is realized in this at random, every batch of experiment is required for manually mobile and specified Quality Control position, can be interfered by various factors.
The no good solution of randomization of ELISA Quality Controls at present, method are the processes in every batch of experiment sample-adding
Middle be randomly placed in quality-control product realizes that this mode makes sample-adding sample continuity be destroyed, sample at random in the lot sample sheet
By other detecting systems using when sample number may occur or information obscures mistake, quality-control product is placed may in sample sequence
It can pollute, influence the reliability of testing result；Certain position is specified to realize when sample-adding random, this mode can not rule out personnel
Influence factor, testing staff may even refer to without position according to personal custom, specified quality-control product fixed position relative
It is fixed, cause randomness poor, cannot find in time in detection process there may be the problem of, if disparity items be once loaded it is multiple
Quality-control product is also easy to make to obscure when testing staff designated position, and Quality Control is caused to be loaded mistake.
Invention content
The purpose of the present invention is the above-mentioned deficiency for the prior art, provide a kind of enzyme linked immunosorbent detection based on time sequence
The random Quality Control loading methods of row.
It is a further object of the present invention to provide a kind of enzyme-linked immune detection methods.
It is yet another object of the invention to provide a kind of automatic sample equipment.
The random Quality Control loading methods based on time series of enzyme linked immunosorbent detection, including positive and negative control and quality-control product
It is loaded sequence frame and sample application sequence rack position and each frame placement sample, Quality Control or control site is constant, sample injector was loaded
According to the variation of time conditions in journey, mathematical model is calculated and carries out sequence location and is replaced automatically, automatically by fixed bit
Set Quality Control inhale sample after at random to the holes elisa plate 1-m any position, picking is consolidated by sample application to the protoplasm control that random Quality Control is replaced
Positioning is set, and is ultimately formed in 1-m samples comprising the unfixed sample-adding combination of quality-control product and quality-control product position；The mathematical model
For aRandom number*s。aRandom numberThe arbitrary random number between 0-1, s are batch detection sample number (1-m)；Automatic sample-adding system STAR-VENAS
The HSL method editing machines on backstage are based primarily upon C/C++ language；The last position for taking the current experiment time " dividing ", switchs to ASCII character postscript
For N1, it is N2 that the last position of second, which switchs to ASCII character postscript, and numerical value of N 3 is calculated using the formula of N1*10+N2；Repeat N3 tune
With random number generator MthR01Draw () function, MthR01Draw () function is used to generate the random number between a 0-1,
It is denoted as aRandom number, a is multiplied by with batch sample number (1-m)Random number, the non-integer between a 0-m is obtained, finally the number is used
MthRound functions round up to obtain respective integer, the random Quality Control position using the integer as the batch sample, the position
Number is more than or equal to 0 and is less than or equal to batch Sample Maximal number, if value taken is exactly 0 in extreme circumstances, then it represents that Quality Control
Position rests on foramen primum and does not exchange；The wherein m is the hole count of ELISA Plate.
The m preferably 88 or 96.
A kind of enzyme-linked immune detection method, Quality Control hole therein are randomly provided based on time series；Positive and negative compare and matter
Control product are loaded sequence frame and sample application sequence rack position and each frame placement sample, Quality Control or control site are constant, and sample injector adds
According to the variation of time conditions during sample, mathematical model is calculated and carries out sequence location and is replaced automatically, will be consolidated automatically
It positions after setting Quality Control suction sample at random to the holes elisa plate 1-m any position, the sample application that picking is replaced by random Quality Control to protoplasm
Fixed position is controlled, is ultimately formed in 1-m samples comprising the unfixed sample-adding combination of quality-control product and quality-control product position；The mathematics
Model is aRandom number*s。aRandom numberThe arbitrary random number between 0-1, s are batch detection sample number (1-m)；Automatic sample-adding system STAR-
The HSL method editing machines on the backstages VENAS are based primarily upon C/C++ language；The last position for taking the current experiment time " dividing ", switchs to ASCII
Code postscript is N1, and it is N2 that the last position of second, which switchs to ASCII character postscript, and numerical value of N 3 is calculated using the formula of N1*10+N2；It repeats
N3 calling random number generator MthR01Draw () function, MthR01Draw () function be used to generate between a 0-1 with
Machine number, is denoted as aRandom number, a is multiplied by with batch sample number (1-m)Random number, the non-integer between a 0-m is obtained, finally the number is used
MthRound functions round up to obtain respective integer, the random Quality Control position using the integer as the batch sample, the position
Number is more than or equal to 0 and is less than or equal to batch Sample Maximal number, if value taken is exactly 0 in extreme circumstances, then it represents that Quality Control
Position rests on foramen primum and does not exchange；The wherein m is the hole count of ELISA Plate.
The m preferably 88 or 96.
A kind of automatic sample equipment, including control centre, the control centre controls positive and negative control, random Quality Control
Product and sample are loaded as follows：According to the variation of time conditions during sample injector sample-adding, mathematical model is counted
It calculates and carries out sequence location and replace automatically, at random to the holes elisa plate 1-m any position, will be chosen after fixed position Quality Control suction sample automatically
Take the sample application replaced by random Quality Control to protoplasm control fixed position, it includes quality-control product and Quality Control to ultimately form in 1-m samples
Grade sets unfixed sample-adding combination；The mathematical model is aRandom number*s。aRandom numberThe arbitrary random number between 0-1, s are batch inspection
Survey sample number (1-m)；The HSL method editing machines on the backstages automatic sample-adding system STAR-VENAS are based primarily upon C/C++ language；It takes and works as
The last position of preceding experimental period " dividing ", it is N1 to switch to ASCII character postscript, and it is N2 that the last position of second, which switchs to ASCII character postscript, using N1*
Numerical value of N 3 is calculated in the formula of 10+N2；N3 calling random number generator MthR01Draw () function is repeated,
MthR01Draw () function is used to generate the random number between a 0-1, is denoted as aRandom number, it is multiplied by with batch sample number (1-m)
aRandom number, the non-integer between a 0-m is obtained, finally the number is rounded up to obtain respective integer using MthRound functions,
Random Quality Control position using the integer as the batch sample, the positional number are more than or equal to 0 and are less than or equal to batch Sample Maximal
Number, if value taken is exactly 0 in extreme circumstances, then it represents that Quality Control position rests on foramen primum and do not exchange；The wherein m
For the hole count of ELISA Plate.
The m preferably 88 or 96.
Advantageous effect：
Invention introduces time serieses, cause algorithm by the variation of time point and second using Monte Carlo EGS4 method
Variation makes batch interior Quality Control position randomly generate, and each hole position of elisa plate can be supervised by solving enzyme linked immune assay Quality Control
It surveys, influence of the edge effect to testing result can be discovered.
Description of the drawings
Fig. 1 quality-control product load positions
168 batches of Fig. 2 test quality-control product and are loaded frequency
Fig. 3 uses Microsoft EXCEL rand () functional simulation 60000 times, and each hole is added to the frequency of quality-control product
Specific implementation mode
Embodiment 1
The sample-adding that random Quality Control is carried out using 88 orifice plates is tested, and positive and negative control and quality-control product are loaded sequence frame and sample
It is loaded sequence rack position and each frame placement sample, Quality Control or control site is constant, according to time conditions during sample injector sample-adding
Variation, mathematical model is calculated and carries out sequence location and is replaced automatically, automatically will fixed position Quality Control inhale it is random after sample
To the holes elisa plate 1-88 any position, the sample application that picking is replaced by random Quality Control is ultimately formed to protoplasm control fixed position
Include the unfixed sample-adding combination of quality-control product and quality-control product position in 1-88 samples；The mathematical model is aRandom number*s。aRandom number
The arbitrary random number between 0-1, s are batch detection sample number (1-88)；The HSL methods on the backstages automatic sample-adding system STAR-VENAS
Editing machine is based primarily upon C/C++ language；The last position for taking the current experiment time " dividing ", it is N1, the last position of second to switch to ASCII character postscript
It is N2 to switch to ASCII character postscript, and numerical value of N 3 is calculated using the formula of N1*10+N2；Repeat N3 calling random number generator
MthR01Draw () function, MthR01Draw () function are used to generate the random number between a 0-1, are denoted as aRandom number, use lot sample
This number (1-88) is multiplied by aRandom number, the non-integer between a 0-88 is obtained, five finally are given up using MthRound functions 4 to the number
Enter to obtain respective integer, the random Quality Control position using the integer as the batch sample, which is more than or equal to 0 and is less than etc.
In batch Sample Maximal number, if value taken is exactly 0 in extreme circumstances, then it represents that Quality Control position rests on foramen primum and do not hand over
It changes.
After sample-adding starts, the time of beginning is exemplified as sample injector：8 points 23 seconds 45 minutes, point last position be 5, the last position of second
It is 3, difference value, and it is converted into ASCII character, it is 0.86 to call the random number of random number (between 0-1) operation according to formula, from
Dynamic rounding is 0.9, is multiplied by sample total (batch maximum value is 88), if sample size is 88, then random Quality Control position is No. 72 positions.
By 73 days by a definite date, the random Quality Control sample-adding of 168 batches (88 sample of whole plate) was carried out altogether, each hole is added to quality-control product
Specific location and frequency see Fig. 1, Fig. 2.
The batch tested at present does not have enough, and there is also the Quality Control position not being fetched into, the frequency that individual holes take also is deposited
In higher situation, but according to mathematical model by taking 88 samples of whole plate as an example, using Microsoft EXCEL rand () letter
Number[3]Simulation 60000 times, the specific component of frequency that each hole is added to quality-control product is shown in Fig. 3.In the case where batch number is enough, 1-
87 each hole random frequencies are close, and the frequency that 0 hole (not making exchange hole) occurs with the 88th hole is the 50% of remaining hole.
Claims (6)
1. the random Quality Control loading methods based on time series of enzyme linked immunosorbent detection, it is characterised in that compareed including positive and negative
And quality-control product is loaded sequence frame and sample application sequence rack position and each frame placement sample, Quality Control or control site are constant, sample-adding
According to the variation of time conditions during device sample-adding, mathematical model is calculated and carries out sequence location and is replaced automatically, automatically
By, at random to the holes elisa plate 1-m any position, the sample application that picking is replaced by random Quality Control is extremely after fixed position Quality Control suction sample
Protoplasm control fixed position ultimately forms in 1-m samples comprising the unfixed sample-adding combination of quality-control product and quality-control product position；Described
Mathematical model is aRandom number*s。aRandom numberThe arbitrary random number between 0-1, s are batch detection sample number (1-m)；Automatic sample-adding system
The HSL method editing machines on the backstages STAR-VENAS are based primarily upon C/C++ language；The last position for taking the current experiment time " dividing ", switchs to
ASCII character postscript is N1, and it is N2 that the last position of second, which switchs to ASCII character postscript, and numerical value of N 3 is calculated using the formula of N1*10+N2；
N3 calling random number generator MthR01Draw () function is repeated, MthR01Draw () function is between one 0-1 of generation
Random number, be denoted as aRandom number, a is multiplied by with batch sample number (1-m)Random number, the non-integer between a 0-m is obtained, finally to the number
It rounds up to obtain respective integer using MthRound functions, the random Quality Control position using the integer as the batch sample, it should
Positional number is more than or equal to 0 and is less than or equal to batch Sample Maximal number, if value taken is exactly 0 in extreme circumstances, then it represents that
Quality Control position rests on foramen primum and does not exchange；The wherein m is the hole count of ELISA Plate.
2. the random Quality Control loading methods based on time series of enzyme linked immunosorbent detection according to claim 1, feature
It is that m is 88 or 96.
3. a kind of enzyme-linked immune detection method, it is characterised in that Quality Control hole therein is randomly provided based on time series；Positive and negative
Control and quality-control product sample-adding sequence frame and sample application sequence rack position and each frame placement sample, Quality Control or control site are constant,
According to the variation of time conditions during sample injector sample-adding, mathematical model is calculated and carries out sequence location and is replaced automatically,
Automatically by, at random to the holes elisa plate 1-m any position, picking is added by the sample that random Quality Control is replaced after fixed position Quality Control suction sample
Sample ultimately forms in 1-m samples to protoplasm control fixed position comprising the unfixed sample-adding combination of quality-control product and quality-control product position；Institute
The mathematical model stated is aRandom number*s。aRandom numberThe arbitrary random number between 0-1, s are batch detection sample number (1-m)；Automatic sample system
The HSL method editing machines on the backstages system STAR-VENAS are based primarily upon C/C++ language；The last position of current experiment time " dividing " is taken, is turned
It is N1 for ASCII character postscript, it is N2 that the last position of second, which switchs to ASCII character postscript, and numerical value is calculated using the formula of N1*10+N2
N3；N3 calling random number generator MthR01Draw () function is repeated, MthR01Draw () function is for generating a 0-1
Between random number, be denoted as aRandom number, a is multiplied by with batch sample number (1-m)Random number, the non-integer between a 0-m is obtained, it is finally right
The number rounds up to obtain respective integer using MthRound functions, the random Quality Control position using the integer as the batch sample
It sets, which is more than or equal to 0 and is less than or equal to batch Sample Maximal number, if value taken is exactly 0 in extreme circumstances,
Indicate that Quality Control position rests on foramen primum and do not exchange；The wherein m is the hole count of ELISA Plate.
4. enzyme-linked immune detection method according to claim 3, it is characterised in that m is 88 or 96.
5. a kind of automatic sample equipment, it is characterised in that include control centre, the control centre control positive and negative control,
Random quality-control product and sample are loaded as follows：According to the variation of time conditions during sample injector sample-adding, to mathematical modulo
Type is calculated and carries out sequence location and replaced automatically, is appointed at random to the holes elisa plate 1-m after sample is inhaled in fixed position Quality Control automatically
Meaning position, the sample application that picking is replaced by random Quality Control to protoplasm control fixed position, it includes Quality Control to ultimately form in 1-m samples
The unfixed sample-adding combination of product and quality-control product position；The mathematical model is aRandom number*s。aRandom numberIt is arbitrary random between 0-1
Number, s are batch detection sample number (1-m)；The HSL method editing machines on the backstages automatic sample-adding system STAR-VENAS are based primarily upon C/C+
+ language；The last position for taking the current experiment time " dividing ", it is N1 to switch to ASCII character postscript, and the last position of second switchs to ASCII character postscript and is
Numerical value of N 3 is calculated using the formula of N1*10+N2 in N2；Repeat N3 calling random number generator MthR01Draw () letter
Number, MthR01Draw () function are used to generate the random number between a 0-1, are denoted as aRandom number, it is multiplied by with batch sample number (1-m)
aRandom number, the non-integer between a 0-m is obtained, finally the number is rounded up to obtain respective integer using MthRound functions,
Random Quality Control position using the integer as the batch sample, the positional number are more than or equal to 0 and are less than or equal to batch Sample Maximal
Number, if value taken is exactly 0 in extreme circumstances, then it represents that Quality Control position rests on foramen primum and do not exchange；The wherein m
For the hole count of ELISA Plate.
6. automatic sample equipment according to claim 5, it is characterised in that m is 88 or 96.
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114188034A (en) * | 2021-11-26 | 2022-03-15 | 广州金域医学检验中心有限公司 | Sample entry method, device, equipment and storage medium |
Citations (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH03212882A (en) * | 1990-01-16 | 1991-09-18 | Mitsubishi Electric Corp | Music selector |
| EP0780807A2 (en) * | 1995-12-19 | 1997-06-25 | Pitney Bowes Inc. | A method of mapping destination addresses for use in calculating digital tokens |
| KR19980087373A (en) * | 1997-05-26 | 1998-12-05 | 가네코 히사시 | Shape Simulation Method and System of Plasma-Assist Etching Process |
| WO2004032024A2 (en) * | 2002-09-30 | 2004-04-15 | Random Perfect, Llc | Method and system for random sampling |
| DE102005019985B4 (en) * | 2005-04-27 | 2010-12-30 | Accurro Gmbh | A method for the controlled removal of a number of vials from a freeze dryer and apparatus therefor |
| CN102111873A (en) * | 2009-12-23 | 2011-06-29 | 中国移动通信集团公司 | Method and device for selecting visible base station as well as method and device for locating terminal |
| CN102541508A (en) * | 2010-12-29 | 2012-07-04 | 鸿富锦精密工业（深圳）有限公司 | True random number generating system and method |
| CN103025859A (en) * | 2010-05-25 | 2013-04-03 | 阿尔利克斯公司 | Methods and apparatuses for detection of positional freedom of particles in biological and chemical analyses and applications in immunodiagnostics |
| RU2011140441A (en) * | 2011-10-06 | 2013-05-10 | Александр Владимирович Попов | METHOD FOR CONDUCTING A LOTTERY AND A DEVICE FOR ITS IMPLEMENTATION |
| CN103307704A (en) * | 2013-06-20 | 2013-09-18 | 深圳麦克维尔空调有限公司 | Assignment method of communication addresses of main outdoor unit and multiple slave indoor units of air conditioner |
| CN103399726A (en) * | 2013-07-15 | 2013-11-20 | 哈尔滨工程大学 | Streamlined combined-type pseudo-random number generator |
| CN103441188A (en) * | 2013-09-03 | 2013-12-11 | 宁夏东旭太阳能科技有限公司 | Method for drawing samples from thin-film solar cell production line |
| CN103869089A (en) * | 2012-12-11 | 2014-06-18 | 奥索临床诊断有限公司 | Method for holding multiple types of diagnostic test consumables in a random access single container |
| CN104297504A (en) * | 2014-10-22 | 2015-01-21 | 上海申腾信息技术有限公司 | Automatic gas chromatographic control system |
| CN107646089A (en) * | 2015-03-06 | 2018-01-30 | 英国质谱公司 | Spectrum analysis |
-
2018
- 2018-04-20 CN CN201810356966.7A patent/CN108717119B/en active Active
Patent Citations (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH03212882A (en) * | 1990-01-16 | 1991-09-18 | Mitsubishi Electric Corp | Music selector |
| EP0780807A2 (en) * | 1995-12-19 | 1997-06-25 | Pitney Bowes Inc. | A method of mapping destination addresses for use in calculating digital tokens |
| KR19980087373A (en) * | 1997-05-26 | 1998-12-05 | 가네코 히사시 | Shape Simulation Method and System of Plasma-Assist Etching Process |
| WO2004032024A2 (en) * | 2002-09-30 | 2004-04-15 | Random Perfect, Llc | Method and system for random sampling |
| DE102005019985B4 (en) * | 2005-04-27 | 2010-12-30 | Accurro Gmbh | A method for the controlled removal of a number of vials from a freeze dryer and apparatus therefor |
| CN102111873A (en) * | 2009-12-23 | 2011-06-29 | 中国移动通信集团公司 | Method and device for selecting visible base station as well as method and device for locating terminal |
| CN103025859A (en) * | 2010-05-25 | 2013-04-03 | 阿尔利克斯公司 | Methods and apparatuses for detection of positional freedom of particles in biological and chemical analyses and applications in immunodiagnostics |
| CN102541508A (en) * | 2010-12-29 | 2012-07-04 | 鸿富锦精密工业（深圳）有限公司 | True random number generating system and method |
| RU2011140441A (en) * | 2011-10-06 | 2013-05-10 | Александр Владимирович Попов | METHOD FOR CONDUCTING A LOTTERY AND A DEVICE FOR ITS IMPLEMENTATION |
| CN103869089A (en) * | 2012-12-11 | 2014-06-18 | 奥索临床诊断有限公司 | Method for holding multiple types of diagnostic test consumables in a random access single container |
| CN103307704A (en) * | 2013-06-20 | 2013-09-18 | 深圳麦克维尔空调有限公司 | Assignment method of communication addresses of main outdoor unit and multiple slave indoor units of air conditioner |
| CN103399726A (en) * | 2013-07-15 | 2013-11-20 | 哈尔滨工程大学 | Streamlined combined-type pseudo-random number generator |
| CN103441188A (en) * | 2013-09-03 | 2013-12-11 | 宁夏东旭太阳能科技有限公司 | Method for drawing samples from thin-film solar cell production line |
| CN104297504A (en) * | 2014-10-22 | 2015-01-21 | 上海申腾信息技术有限公司 | Automatic gas chromatographic control system |
| CN107646089A (en) * | 2015-03-06 | 2018-01-30 | 英国质谱公司 | Spectrum analysis |
Non-Patent Citations (8)
| Title |
|---|
| PAUL J. GROOT-KORMELINK等: "High Throughput Random Mutagenesis and Single Molecule Real Time Sequencing of the Muscle Nicotinic Acetylcholine Receptor", 《PLOS ONE》 * |
| PIOTR ZYGMANSKI等: "Dependence of fluence errors in dynamic IMRT on leaf-positional errors varying with time and leaf number", 《MED. PHYS.》 * |
| STEFAN LANG等: "Multilevel structured additive regression", 《STAT COMPUT》 * |
| 何凤霞等: "蒙特卡罗方法的应用及算例", 《华北电力大学学报》 * |
| 周苏等: "《项目管理与应用》", 31 March 2012, 中国铁道出版社 * |
| 张立波等: "全自动酶免分析仪不同孵育槽及不同位置检测结果分析", 《中国输血杂志》 * |
| 田浩杉等: "基于时序蒙特卡洛的WSN节点定位算法", 《传感技术学报》 * |
| 马海龙: "《空间治理基础》", 31 August 2017, 宁夏人民出版社 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114188034A (en) * | 2021-11-26 | 2022-03-15 | 广州金域医学检验中心有限公司 | Sample entry method, device, equipment and storage medium |
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