CN108670995A - A kind of extraction process of wild wild ginseng medicinal material - Google Patents
A kind of extraction process of wild wild ginseng medicinal material Download PDFInfo
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- CN108670995A CN108670995A CN201810706331.5A CN201810706331A CN108670995A CN 108670995 A CN108670995 A CN 108670995A CN 201810706331 A CN201810706331 A CN 201810706331A CN 108670995 A CN108670995 A CN 108670995A
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- heavy metal
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- extraction
- botanical herbs
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
- A61K36/258—Panax (ginseng)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/38—Cellulose; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/46—Ingredients of undetermined constitution or reaction products thereof, e.g. skin, bone, milk, cotton fibre, eggshell, oxgall or plant extracts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/37—Extraction at elevated pressure or temperature, e.g. pressurized solvent extraction [PSE], supercritical carbon dioxide extraction or subcritical water extraction
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Botany (AREA)
- Engineering & Computer Science (AREA)
- Alternative & Traditional Medicine (AREA)
- Biotechnology (AREA)
- Inorganic Chemistry (AREA)
- Medical Informatics (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The invention discloses a kind of extraction processes of wild wild ginseng medicinal material, it is characterised in that：Include the following steps：1）Botanical herbs are cleaned, are dried, are crushed to 20 ~ 30 mesh；2）Use supercritical CO2Extraction process removes step 1）Heavy metal in gained Chinese medicine particle；3）By step 2）The middle botanical herbs particle for removing heavy metal bakes：It 45 ~ 50 DEG C, bakes 50 ~ 60 minutes, 0.3 ~ 0.5wt% of water content.The present invention has been added to the pre-treatment step that medicinal material removes heavy metal pollution, effectively prevents the pollution of heavy metal that may be present, guarantee is provided for the extraction and purifying of precious Chinese herbal medicine active ingredient.
Description
Technical field
The present invention relates to technical field of plant extraction, mainly a kind of extraction process of wild wild ginseng medicinal material.
Background technology
Chinese medicine is people to diseases prevention, the specialty goods cured the disease, and answers effect harmless to the human body first.Chinese medicine is once
By pesticide and heavy metal pollution, it would be possible to potential threat, especially patient are generated to human body, often function of detoxification is poor,
Caused by hazard ratio ordinary person's bigger, cannot not only cure the disease in this way, instead aggravate and be delayed patient treatment.
In recent years, cosmopolitian plant medicine market annual sales amount is up to 40,000,000,000 dollars, and with annual 10% speed increase,
But the big country that China is produced as autonomic drug, the influence due to pesticide, heavy-metal residual in Chinese medicine etc., Chinese medicine always go out
Mouth volume only accounts for 1% or so of cosmopolitian plant medicine sales volume at present, and pesticide, heavy-metal residual pollution have become Chinese medicine and go to the world
" bottleneck ".It can be seen that Chinese medicine pesticide and heavy metal pollution have become it is urgently to be resolved hurrily important in current Producing medicinal herbs
Problem.For, in links such as processing, transports, stringent content of beary metal to control, early monitoring and controlling quality in Chinese medicine.Such as
In Radix Notoginseng process, it is greatly lowered than direct processing of lucid ganoderma huge sum of money cellulose content using the ganoderma lucidum of cleaning post-processing,
Bringing into for bad auxiliary material is reduced in concocting process, it is rapid to formulate tcm and herbal slice specification.
Invention content
The purpose of the present invention exactly will solve the disadvantage that the above-mentioned prior art, provide a kind of extraction work of wild wild ginseng medicinal material
Skill.The purpose of the present invention can be achieved through the following technical solutions：
A kind of extraction process of wild wild ginseng medicinal material, it is characterised in that：Include the following steps： 1）By botanical herbs cleaning, dry
It does, be crushed to 20 ~ 30 mesh；
2）Step 1 is removed with supercritical CO_2 extraction technique）Heavy metal in gained Chinese medicine particle；
3）By step 2）The middle botanical herbs particle for removing heavy metal bakes：It 45 ~ 50 DEG C, bakes 50 ~ 60 minutes, water content
0.3~0.5wt% ；
4) by step 3）Botanical herbs particle ultramicro grinding after baking is to 0.35 ~ 0.75 μm of grain size；
5）Broken wall treatment：To step 4）It is effective that the micro-nano wall breaking technology extraction of auxiliary material low temperature is added in gained botanical herbs particle
Ingredient, the auxiliary material are starched for black rice, tea polyphenols and sodium carboxymethylcellulose, have both obtained rare species Chinese medicine and have exempted from decoction.
Advantageous effect：The present invention has been added to the pre-treatment step that medicinal material removes heavy metal pollution, effectively prevents possibility
The pollution of existing heavy metal provides guarantee for the extraction and purifying of precious Chinese herbal medicine active ingredient.The micro-nano broken wall of low temperature
Technique to high-efficiency rate, it is pollution-free, effective ingredient can be extracted to greatest extent, reduce the loss of effective ingredient.
Specific implementation mode
Using specific implementation mode below, present invention will be explained in further detail；
A kind of extraction process of wild wild ginseng medicinal material, it is characterised in that：Include the following steps： 1）By botanical herbs cleaning, dry
It does, be crushed to 20 ~ 30 mesh；
2）Step 1 is removed with supercritical CO_2 extraction technique）Heavy metal in gained Chinese medicine particle；
3）By step 2）The middle botanical herbs particle for removing heavy metal bakes：It 45 ~ 50 DEG C, bakes 50 ~ 60 minutes, water content
0.3~0.5wt% ；
4) by step 3）Botanical herbs particle ultramicro grinding after baking is to 0.35 ~ 0.75 μm of grain size；
5）Broken wall treatment：To step 4）It is effective that the micro-nano wall breaking technology extraction of auxiliary material low temperature is added in gained botanical herbs particle
Ingredient, the auxiliary material are starched for black rice, tea polyphenols and sodium carboxymethylcellulose, have both obtained rare species Chinese medicine and have exempted from decoction.
Claims (1)
1. a kind of extraction process of wild wild ginseng medicinal material, it is characterised in that：Include the following steps： 1）Botanical herbs are cleaned,
It dries, be crushed to 20 ~ 30 mesh；
2）Step 1 is removed with supercritical CO_2 extraction technique）Heavy metal in gained Chinese medicine particle；
3）By step 2）The middle botanical herbs particle for removing heavy metal bakes：It 45 ~ 50 DEG C, bakes 50 ~ 60 minutes, water content
0.3~0.5wt% ；
4) by step 3）Botanical herbs particle ultramicro grinding after baking is to 0.35 ~ 0.75 μm of grain size；
5）Broken wall treatment：To step 4）It is effective that the micro-nano wall breaking technology extraction of auxiliary material low temperature is added in gained botanical herbs particle
Ingredient, the auxiliary material are starched for black rice, tea polyphenols and sodium carboxymethylcellulose, have both obtained rare species Chinese medicine and have exempted from decoction.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810706331.5A CN108670995A (en) | 2018-07-02 | 2018-07-02 | A kind of extraction process of wild wild ginseng medicinal material |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810706331.5A CN108670995A (en) | 2018-07-02 | 2018-07-02 | A kind of extraction process of wild wild ginseng medicinal material |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN108670995A true CN108670995A (en) | 2018-10-19 |
Family
ID=63812913
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201810706331.5A Pending CN108670995A (en) | 2018-07-02 | 2018-07-02 | A kind of extraction process of wild wild ginseng medicinal material |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN108670995A (en) |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105232584A (en) * | 2015-09-30 | 2016-01-13 | 河南行知专利服务有限公司 | Decoction-free extraction process for precious Chinese herbal medicines |
| CN107260994A (en) * | 2017-06-21 | 2017-10-20 | 杨育川 | A kind of Chinese medicine dietotherapy composition of anti-curing oncoma and preparation method thereof |
-
2018
- 2018-07-02 CN CN201810706331.5A patent/CN108670995A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105232584A (en) * | 2015-09-30 | 2016-01-13 | 河南行知专利服务有限公司 | Decoction-free extraction process for precious Chinese herbal medicines |
| CN107260994A (en) * | 2017-06-21 | 2017-10-20 | 杨育川 | A kind of Chinese medicine dietotherapy composition of anti-curing oncoma and preparation method thereof |
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| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| WD01 | Invention patent application deemed withdrawn after publication | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20181019 |