CN108670483A - Based on shock wave animal bone injury generating means and standardization fracture experimental method - Google Patents
Based on shock wave animal bone injury generating means and standardization fracture experimental method Download PDFInfo
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- CN108670483A CN108670483A CN201810602723.7A CN201810602723A CN108670483A CN 108670483 A CN108670483 A CN 108670483A CN 201810602723 A CN201810602723 A CN 201810602723A CN 108670483 A CN108670483 A CN 108670483A
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- shock wave
- annular support
- pipette tips
- bone injury
- generating means
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- 230000035939 shock Effects 0.000 title claims abstract description 54
- 206010061363 Skeletal injury Diseases 0.000 title claims abstract description 30
- 241001465754 Metazoa Species 0.000 title claims abstract description 27
- 238000002474 experimental method Methods 0.000 title claims description 29
- NJPPVKZQTLUDBO-UHFFFAOYSA-N novaluron Chemical compound C1=C(Cl)C(OC(F)(F)C(OC(F)(F)F)F)=CC=C1NC(=O)NC(=O)C1=C(F)C=CC=C1F NJPPVKZQTLUDBO-UHFFFAOYSA-N 0.000 claims abstract description 19
- 230000033001 locomotion Effects 0.000 claims abstract description 5
- 238000010276 construction Methods 0.000 claims abstract description 4
- 125000004122 cyclic group Chemical group 0.000 claims description 4
- 238000000034 method Methods 0.000 claims description 4
- 238000003756 stirring Methods 0.000 claims description 4
- 206010052428 Wound Diseases 0.000 description 3
- 238000010586 diagram Methods 0.000 description 3
- 241000282465 Canis Species 0.000 description 2
- 208000015181 infectious disease Diseases 0.000 description 2
- 238000004080 punching Methods 0.000 description 2
- 229920006395 saturated elastomer Polymers 0.000 description 2
- 208000034656 Contusions Diseases 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 210000000988 bone and bone Anatomy 0.000 description 1
- 230000009519 contusion Effects 0.000 description 1
- 230000006378 damage Effects 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 210000001519 tissue Anatomy 0.000 description 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61D—VETERINARY INSTRUMENTS, IMPLEMENTS, TOOLS, OR METHODS
- A61D1/00—Surgical instruments for veterinary use
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Surgery (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Abstract
One kind being based on shock wave animal bone injury generating means, it is characterized by comprising annular support (1), the pedestal (2) being connect with annular support (1) and the identical shock wave pipette tips (3) of four constructions, the shock wave pipette tips (3) are the cylinder that both sides are scabbled, there are external screw thread (31) and graduation mark (32) in its surface, have on the annular support (1) in radiosymmetric 4 rotating disc hollow holes (11), rotating disc (12) there are one being set in each rotating disc hollow hole, the internal thread (120) of rotating disc (12) is threadedly coupled with the external screw thread (31) of shock wave pipette tips (3), distance of rotary motion disk (12) the adjustable impact wave pipette tips (3) with respect to annular support (1) center of circle.Repeatability of the invention is strong, and stability is good, can effectively reduce the error between sample.The present invention can obtain different bone injury models by adjusting blast wave generating apparatus power, and be conducive to quantitative study.
Description
Technical field
The present invention relates to animal experiment technique fields, are specially based on shock wave animal bone injury generating means and standardization
Fracture experimental method.
Background technology
Fracture is common clinical with other bone injuries, most important by animal experiment study bone injury.Therefore it makes
Have the animal bone injury sample of unified standard very it is necessary to.Before making the present invention, some Animal Bone damage model instruments are universal
It is big that there are randomnesss, and repeatability is low, and accuracy is not high, the problems such as being unable to quantitative study.Traditional one side of bone injury generating means
Face has randomness to lead to sample error at strike position, is on the other hand likely to cause the open wound of easy infection, brings bigger
Uncertainty and to experiment interfere.
Invention content
The purpose of the present invention is that solve the above-mentioned problems and provides a kind of based on the generation of shock wave animal bone injury
Device and standardization fracture experimental method.Small it is an object of the invention to design a kind of experimental error, repeatability is strong, does not have
The animal bone injury generating means that open wound influences.
The present invention is achieved through the following technical solutions above-mentioned purpose,
The present invention's is mainly characterized by:For band there are four the annular support of shock wave pipette tips jack, both sides connection is solid
Fixed rack is stood on experimental bench, the cylinder that four shells are scabbled in both sides and threaded shock wave pipette tips, on annular support
Graduated scale is connected, pipette tips screw thread is corresponding with annular support screw thread.
One kind being based on shock wave animal bone injury generating means, including annular support 1, the pedestal 2 that is connect with annular support 1
And the identical shock wave pipette tips 3 of four constructions, the shock wave pipette tips 3 are the cylinder that both sides are scabbled, and there is outer spiral shell on surface
Line 31 and graduation mark 32 have in radiosymmetric 4 rotating disc hollow holes 11 on the annular support 1, and each rotating disc is engraved
It is set in emptying aperture there are one rotating disc 12, the internal thread 120 of rotating disc 12 is threadedly coupled with the external screw thread 31 of shock wave pipette tips 3, is revolved
Distance of the 12 adjustable impact wave pipette tips 3 of Moving plate of walking around with respect to 1 center of circle of annular support.
3 tail portion of shock wave pipette tips occurs regulation device with shock wave and is connected.
The base support 2 includes cross bar 22 and montant 23, and base support 2 can steadily stand on level table, and there are
The vacancy passed through for the shock wave pipette tips.
1 side of the annular support is equipped with strip hollow out 13, and 1 outer ring surface of annular support is equipped with locating enchasing 15, for pedestal 2
Cross bar 22 pass through, strip hollow out 13 makes 2 adjustable position of annular support and angle.
The position after shock wave pipette tips 3 of the annular support 1 is equipped with graduated scale 14.
It is the cylinder that both sides are scabbled that 3 form of pipette tips, which occurs, for shock wave, has external screw thread 31 and graduation mark 32 thereon, when opposite
Two pipette tips in direction are screwed into annulus and make it when circle centre position is close to, and scale corresponding to two pipette tips is zero.Both ends according to
It is read according to being read with circular holder boundary line, it is long that reading addition obtains this direction animal leg anteroposterior diameter.
The cross bar 22 is equipped with the aperture 21 of corresponding locating enchasing 15, is passed through to stationary ring holder 1 for screw,
Make annular support 1 relative to the angle and front and back position on 2 adjustable vertical plane of pedestal.
A kind of standardization based on shock wave animal bone injury generating means using as described in claim 1 to 6 is fractured
Experimental method, it is characterised in that include the following steps：
It is positioned on level table, experiment sample is lain on one's side simultaneously numb based on shock wave animal bone injury generating means by described
Liquor-saturated, label needs the leg position through row bone injury modelling, is put into annular support 1, and mark is made to be propped up with cyclic annular
Frame 1 is located in same vertical plane；
Annular support 1 is set to obtain required position and angle relative to the movement of pedestal 2, tightening screw makes annular support 1 and bottom
Seat 2 is relatively fixed；
It pipette tips 3 and the leg that makes it be close to experiment sample to stir rotating disc 12 and move shock wave, while passing through and observing rifle punching
The scale corresponding to graduation mark 32 hit in wave pipette tips 3 and adjustment make experiment sample leg be fixed on 1 circle centre position of annular support, root
Experiment sample leg anteroposterior diameter is read according to graduation mark 32 and is recorded；
Required power and opening impact wave generating device are adjusted according to specific experiment situation, proceeds by experimental implementation；
Rotating disc 12 is stirred after operation to back-out shock wave pipette tips 3 outward, and experiment sample canine is removed.
Number reading method：Both ends are read according to the scale reading after graduation mark and pipette tips, and it is to obtain this direction to move that reading, which is added,
Path length before and after object leg.
The beneficial effects of the invention are as follows：
1. repeatability of the invention is strong, stability is good, can effectively reduce the error between sample.
2. the present invention can obtain different bone injury models by adjusting blast wave generating apparatus power, and be conducive to determine
Quantity research.
3. the present invention does not have open wound, tissue contusion or infection is avoided to impact animal bone injury related experiment,
Be conducive to control variable, convenient for analysis.
4. the holder of the present invention can be adjusted flexibly, the demand of different experiments actual conditions is adapted to.
Description of the drawings
Fig. 1 is the overall structure diagram of the present invention；
Fig. 2 is the structural schematic diagram of the rotating disc of the present invention；
Fig. 3 is the partial structural diagram of the present invention.
Specific implementation mode
Following will be combined with the drawings in the embodiments of the present invention, and technical solution in the embodiment of the present invention carries out clear, complete
Site preparation describes, it is clear that described embodiments are only a part of the embodiments of the present invention, instead of all the embodiments.It is based on
Embodiment in the present invention, it is obtained by those of ordinary skill in the art without making creative efforts every other
Embodiment shall fall within the protection scope of the present invention.
Such as Fig. 1 to Fig. 3, one kind being based on shock wave animal bone injury generating means, including annular support 1 and annular support 1
The pedestal 2 of connection and the identical shock wave pipette tips 3 of four constructions, the shock wave pipette tips 3 are the cylinder that both sides are scabbled,
There are external screw thread 31 and graduation mark 32 in surface, has on the annular support 1 in radiosymmetric 4 rotating disc hollow holes 11, often
Rotating disc 12 there are one being set in a rotating disc hollow hole, the internal thread 120 of rotating disc 12 and 31 spiral shell of external screw thread of shock wave pipette tips 3
Line connects, the distance in 12 adjustable impact wave pipette tips of rotary motion disk, 3 opposite 1 center of circle of annular support.
3 tail portion of shock wave pipette tips occurs regulation device with shock wave and is connected.
The base support 2 includes cross bar 22 and montant 23, and base support 2 can steadily stand on level table, and there are
The vacancy passed through for the shock wave pipette tips.
1 side of the annular support is equipped with strip hollow out 13, and 1 outer ring surface of annular support is equipped with locating enchasing 15, for pedestal 2
Cross bar 22 pass through, strip hollow out 13 makes 2 adjustable position of annular support and angle.
The position after shock wave pipette tips 3 of the annular support 1 is equipped with graduated scale 14.
It is the cylinder that both sides are scabbled that 3 form of pipette tips, which occurs, for shock wave, has external screw thread 31 and graduation mark 32 thereon, when opposite
Two pipette tips in direction are screwed into annulus and make it when circle centre position is close to, and scale corresponding to two pipette tips is zero.Both ends according to
It is read according to being read with circular holder boundary line, it is long that reading addition obtains this direction animal leg anteroposterior diameter.
The cross bar 22 is equipped with the aperture 21 of corresponding locating enchasing 15, is passed through to stationary ring holder 1 for screw,
Make annular support 1 relative to the angle and front and back position on 2 adjustable vertical plane of pedestal.
A kind of standardization based on shock wave animal bone injury generating means using as described in claim 1 to 6 is fractured
Experimental method, it is characterised in that include the following steps：
It is positioned on level table, experiment sample is lain on one's side simultaneously numb based on shock wave animal bone injury generating means by described
Liquor-saturated, label needs the leg position through row bone injury modelling, is put into annular support 1, and mark is made to be propped up with cyclic annular
Frame 1 is located in same vertical plane；
Annular support 1 is set to obtain required position and angle relative to the movement of pedestal 2, tightening screw makes annular support 1 and bottom
Seat 2 is relatively fixed；
It pipette tips 3 and the leg that makes it be close to experiment sample to stir rotating disc 12 and move shock wave, while passing through and observing rifle punching
The scale corresponding to graduation mark 32 hit in wave pipette tips 3 and adjustment make experiment sample leg be fixed on 1 circle centre position of annular support, root
Experiment sample leg anteroposterior diameter is read according to graduation mark 32 and is recorded；
Required power and opening impact wave generating device are adjusted according to specific experiment situation, proceeds by experimental implementation；
Rotating disc 12 is stirred after operation to back-out shock wave pipette tips 3 outward, and experiment sample canine is removed.
Number reading method：Both ends are read according to the scale reading after graduation mark and pipette tips, and it is to obtain this direction to move that reading, which is added,
Path length before and after object leg.
It is obvious to a person skilled in the art that invention is not limited to the details of the above exemplary embodiments, Er Qie
In the case of without departing substantially from spirit or essential attributes of the invention, the present invention can be realized in other specific forms.Therefore, no matter
From the point of view of which point, the present embodiments are to be considered as illustrative and not restrictive, and the scope of the present invention is by appended power
Profit requires rather than above description limits, it is intended that all by what is fallen within the meaning and scope of the equivalent requirements of the claims
Variation is included within the present invention.Any reference signs in the claims should not be construed as limiting the involved claims.
In addition, it should be understood that although this specification is described in terms of embodiments, but not each embodiment is only wrapped
Containing an independent technical solution, this description of the specification is merely for the sake of clarity, and those skilled in the art should
It considers the specification as a whole, the technical solutions in the various embodiments may also be suitably combined, forms those skilled in the art
The other embodiment being appreciated that.
Claims (7)
1. one kind being based on shock wave animal bone injury generating means, it is characterised in that including annular support (1) and annular support
(1) pedestal (2) connected and the identical shock wave pipette tips (3) of four constructions, the shock wave pipette tips (3) are what both sides were scabbled
There are external screw thread (31) and graduation mark (32) in cylinder, surface, have on the annular support (1) and turn in radiosymmetric 4
Moving plate hollow hole (11) is set in each rotating disc hollow hole there are one rotating disc (12), the internal thread (120) of rotating disc (12) with
The external screw thread (31) of shock wave pipette tips (3) is threadedly coupled, the relatively cyclic annular branch of rotary motion disk (12) adjustable impact wave pipette tips (3)
The distance in frame (1) center of circle.
2. according to claim 1 be based on shock wave animal bone injury generating means, it is characterised in that the shock wave rifle
Head (3) tail portion occurs regulation device with shock wave and is connected.
3. according to claim 1 be based on shock wave animal bone injury generating means, it is characterised in that base support (2) wraps
Cross bar (22) and montant (23) are included, base support (2) can steadily stand on level table, and there are worn for the shock wave pipette tips
The vacancy crossed.
4. according to claim 3 be based on shock wave animal bone injury generating means, it is characterised in that annular support (1) side
Face is equipped with strip hollow out (13), and annular support (1) outer ring surface is equipped with locating enchasing (15), is passed through for the cross bar (22) of pedestal (2),
Strip hollow out (13) makes annular support (2) adjustable position and angle.
5. it is according to claim 1 be based on shock wave animal bone injury generating means, it is characterised in that annular support (1) in
Position is equipped with graduated scale (14) to shock wave pipette tips (3) afterwards.
6. according to claim 3 be based on shock wave animal bone injury generating means, it is characterised in that the cross bar (22)
It is equipped with the aperture (21) of corresponding locating enchasing (15), is passed through to stationary ring holder (1) for screw, makes annular support
(1) relative to the angle and front and back position on pedestal (2) adjustable vertical plane.
7. a kind of standardization based on shock wave animal bone injury generating means using as described in claim 1 to 6 is fractured real
Proved recipe method, it is characterised in that include the following steps：Horizontal platform is positioned over based on shock wave animal bone injury generating means by described
On face, experiment sample is lain on one's side and anaesthetized, label needs the leg position through row bone injury modelling, is put into cyclic annular branch
In frame (1), mark is made to be located in same vertical plane with annular support (1)；Keep annular support (1) mobile relative to pedestal (2)
Required position and angle are obtained, tightening screw makes annular support (1) be relatively fixed with pedestal (2)；It is mobile to stir rotating disc (12)
Shock wave pipette tips (3) simultaneously make it be close to the leg of experiment sample, while by observing the graduation mark in rifle shock wave pipette tips (3)
(32) scale and adjustment corresponding to make experiment sample leg be fixed on annular support (1) circle centre position, are read according to graduation mark (32)
Go out experiment sample leg anteroposterior diameter and records；Required power and opening impact wave generating device are adjusted according to specific experiment situation,
Proceed by experimental implementation；It stirs rotating disc (12) after operation to back-out shock wave pipette tips (3) outward, by experiment sample dog
Class removes.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810602723.7A CN108670483B (en) | 2018-06-12 | 2018-06-12 | Animal bone injury generating device based on shock waves and standardized fracture experimental method |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810602723.7A CN108670483B (en) | 2018-06-12 | 2018-06-12 | Animal bone injury generating device based on shock waves and standardized fracture experimental method |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN108670483A true CN108670483A (en) | 2018-10-19 |
| CN108670483B CN108670483B (en) | 2023-11-17 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201810602723.7A Active CN108670483B (en) | 2018-06-12 | 2018-06-12 | Animal bone injury generating device based on shock waves and standardized fracture experimental method |
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Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102217979A (en) * | 2011-06-10 | 2011-10-19 | 中国人民解放军第四军医大学 | Device for manufacturing craniocerebral explosion injury models for small animals |
| CN102670322A (en) * | 2012-04-24 | 2012-09-19 | 中国人民解放军成都军区总医院 | Shock wave generating device |
| CN103099686A (en) * | 2012-04-24 | 2013-05-15 | 中国人民解放军成都军区总医院 | Method of establishing crania-cerebral explosion impact injury animal model |
| CN104666034A (en) * | 2015-03-03 | 2015-06-03 | 天津开发区合普工贸有限公司 | In-vitro eyeball fixing device with adjustable size |
| CN106577384A (en) * | 2016-11-30 | 2017-04-26 | 广东电网有限责任公司佛山供电局 | Fish state monitoring device capable of achieving multi-angle thunderstrike |
-
2018
- 2018-06-12 CN CN201810602723.7A patent/CN108670483B/en active Active
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102217979A (en) * | 2011-06-10 | 2011-10-19 | 中国人民解放军第四军医大学 | Device for manufacturing craniocerebral explosion injury models for small animals |
| CN102670322A (en) * | 2012-04-24 | 2012-09-19 | 中国人民解放军成都军区总医院 | Shock wave generating device |
| CN103099686A (en) * | 2012-04-24 | 2013-05-15 | 中国人民解放军成都军区总医院 | Method of establishing crania-cerebral explosion impact injury animal model |
| CN104666034A (en) * | 2015-03-03 | 2015-06-03 | 天津开发区合普工贸有限公司 | In-vitro eyeball fixing device with adjustable size |
| CN106577384A (en) * | 2016-11-30 | 2017-04-26 | 广东电网有限责任公司佛山供电局 | Fish state monitoring device capable of achieving multi-angle thunderstrike |
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| Publication number | Publication date |
|---|---|
| CN108670483B (en) | 2023-11-17 |
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