CN108618285B - Drug-loaded ornament worn through skin based on shape memory polymer - Google Patents
Drug-loaded ornament worn through skin based on shape memory polymer Download PDFInfo
- Publication number
- CN108618285B CN108618285B CN201810495286.3A CN201810495286A CN108618285B CN 108618285 B CN108618285 B CN 108618285B CN 201810495286 A CN201810495286 A CN 201810495286A CN 108618285 B CN108618285 B CN 108618285B
- Authority
- CN
- China
- Prior art keywords
- shape memory
- needle body
- ornament
- loaded
- drug
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Images
Classifications
-
- A—HUMAN NECESSITIES
- A44—HABERDASHERY; JEWELLERY
- A44C—PERSONAL ADORNMENTS, e.g. JEWELLERY; COINS
- A44C9/00—Finger-rings
- A44C9/0053—Finger-rings having special functions
-
- A—HUMAN NECESSITIES
- A44—HABERDASHERY; JEWELLERY
- A44C—PERSONAL ADORNMENTS, e.g. JEWELLERY; COINS
- A44C25/00—Miscellaneous fancy ware for personal wear, e.g. pendants, crosses, crucifixes, charms
- A44C25/007—Charms or amulets
Landscapes
- Adornments (AREA)
- Radiation-Therapy Devices (AREA)
Abstract
The invention relates to a drug-loaded ornament which is worn through skin and based on a shape memory polymer, and particularly belongs to the field of shape memory composite materials. Comprises a shape memory needle body, a needle body base and an ornament; the shape memory needle body and the ornament are respectively fixed on two sides of the needle body base. The shape memory needle body material of the invention is loaded with the sterilization and anti-inflammation medicine, thereby reducing the probability of inflammation of the affected part; the shape memory needle body material has good biocompatibility and biodegradability, and can not cause rejection or anaphylactic reaction; the shape memory needle body material has the shape memory function, can return to the initial shape under certain thermal stimulation, and is convenient for the ornament to be picked; the shape memory needle body can be used as a puncture needle, has beautiful appearance and can be worn after puncture.
Description
Technical Field
The invention relates to a drug-loaded ornament which is worn through skin and based on a shape memory polymer, and particularly belongs to the field of shape memory composite materials.
Background
The beauty-like woman has the habit of wearing ornaments. The ornament is worn properly, and personal quality can be greatly improved. Some minority nationalities in south China have custom of punching ear holes in babies who are born right now, and the old can bring the baby with a tremella ring when the baby is one year old, representing blessing and guarding for the baby. With the development of the times, wearing accessories were no longer restricted to women, and fashionable men began to choose to wear a variety of accessories. Furthermore, the types of ornaments are not limited to ear nails and ear rings, and lip nails, tongue nails, umbilical rings and the like are also gradually accepted by people.
Wearing accessories often requires puncturing of the body tissue. At present, most of puncture of people is a decorrelation beauty institution, and medical quality of practitioners is good and irregular. And the puncture needle is generally used repeatedly, has poor disinfection conditions, is easy to cause disease transmission and wound inflammation, and is easy to leave keloid after healing.
The ornament is most in direct contact with the wearer's skin. If the quality of the raw materials is not over-qualified, the health of the wearer is directly affected. The puncture needle and the ornaments are mostly made of metal materials, and are easy to cause anaphylactic reaction. Nickel is the most common allergen for generating contact dermatitis at present, and all stainless steel ornaments and stainless steel ear-piercing needles release nickel to different degrees, and even if gold is plated, silver is plated, and the release of nickel cannot be prevented. The puncture causes epidermal damage, and the risk of sensitization is particularly great.
To address this problem, researchers have made many beneficial attempts. The publication number is CN203017046U, the invention patent application name is 'ear hole punching simple needle', and discloses an ear hole punching simple needle which comprises a pintle and a needle head fixed on the pintle, wherein a plastic sleeve is sleeved on the needle head. The utility model discloses an ear hole simple and easy needle that punches, through suit plastic sleeve on the syringe needle, after wearing the ear hole, plastic sleeve passes the ear hole with the syringe needle together, then takes out the syringe needle from the ear hole, stays plastic sleeve in the ear hole, can reach the purpose of punching the ear hole, and plastic sleeve remains the certain time after on the ear hole, takes out plastic sleeve again can, convenient operation. The simple needle for punching the ear hole has low cost, can be used as a disposable article, is reliable in disinfection and has no risk of blood spreading diseases.
However, after the simple needle is used for punching the ear hole, an external anti-inflammatory drug or an oral anti-inflammatory drug is needed, the sleeve needs to be rotated every day to prevent the sleeve from being adhered to the skin, and pain can be caused to a patient when the sleeve is taken out.
Disclosure of Invention
The invention aims to solve the problem that the traditional ear needle is easy to cause inflammation and allergy on an affected part. The invention provides a drug-loaded ornament which is worn through skin and based on a shape memory polymer, comprising a shape memory needle body, a needle body base and an ornament; the shape memory needle body and the ornament are respectively fixed on two sides of the needle body base.
Further, the shape memory needle body is made of a shape memory polymer material, and the shape memory polymer material comprises one or more of shape memory polyurethane, shape memory polylactic acid, aliphatic polyester, polyisoprene or polylactide.
Furthermore, the shape memory needle body is molded by extrusion molding, injection molding, compression molding or casting molding.
Furthermore, the shape memory needle body carries one or two of antibacterial drugs and anti-inflammatory drugs.
Further, the shape memory needle body performs rapid shape recovery behavior at the temperature of 40-60 ℃, and recovers to the initial shape after 10-60 s.
Furthermore, the shape memory needle body is driven by heat or infrared light.
Furthermore, the shape-memory needle body is shaped by heat or infrared light.
Compared with the prior art, the invention has the following effects: the invention relates to a drug-loaded ornament which is worn through skin and based on a shape memory polymer.A shape memory needle body material is loaded with a sterilization and anti-inflammation drug, so that the probability of inflammation of an affected part is reduced; the shape memory needle body material has good biocompatibility and biodegradability, and can not cause rejection or anaphylactic reaction; the shape memory needle body material has the shape memory function, can return to the initial shape under certain thermal stimulation, and is convenient for the ornament to be picked; the shape memory needle body can be used as a puncture needle, has beautiful appearance and can be worn after puncture; when the shape memory needle body is worn, the ear plug is not needed, and the ear plug is not needed to be worried about falling off to cause the loss of the ear nail; the ornament has the advantages of simple design and manufacture, low cost, short curing and forming time and wide market application prospect.
The shape memory polymer is an intelligent actively-deformed polymer material which can generate larger recoverable deformation under the action of external excitation. Part of shape memory polymer materials have good biocompatibility and degradability, are applied to thrombus removers, tissue engineering scaffolds, surgical sutures, drug sustained release and the like, and have wide application prospects.
Drawings
FIG. 1 is a schematic structural diagram of a drug-loaded ornament worn through skin based on shape memory polymer according to the present invention;
fig. 2, fig. 3, fig. 4, fig. 5 and fig. 6 are schematic diagrams of shaped structures of a drug-loaded ornament worn through skin based on shape memory polymer according to the present invention;
Detailed Description
The present embodiment will be described with reference to fig. 1 to 6. The drug-loaded ornament which is worn through the skin and based on the shape memory polymer comprises a shape memory needle body 1, a needle body base 2 and an ornament 3; the shape memory needle body 1 and the ornament 3 are respectively fixed on two sides of the needle body base 2.
In order to achieve a good appearance, various decorations can be designed to be fixed on the needle body base 2, and the fixing mode of the decorations and the needle body base 2 is one of bonding, mechanical connection or integral forming.
The shape memory needle body 1 is made of a shape memory polymer material, and the shape memory polymer material comprises one or more of shape memory polyurethane, shape memory polylactic acid, aliphatic polyester, polyisoprene or polylactide. The proportion of the combination of the shape memory polyurethane, the shape memory polylactic acid, the aliphatic polyester, the polyisoprene or the polylactide is any ratio.
When the temperature is higher than the glass transition temperature (Tg) of the shape memory polymer, the shape memory polymer can be deformed by applying external force; keeping the external force unchanged to reduce the temperature to a certain temperature below Tg, and removing the external force to enable the given deformation to be kept for a long time; when the temperature is raised above Tg again, the shape memory polymer can automatically return to the pre-shaped shape.
The shape memory needle body 1 is molded by extrusion molding, injection molding, compression molding or casting molding.
The shape memory needle body 1 carries one or two of antibacterial drugs and anti-inflammatory drugs. The carried medicine accounts for 1-10% of the whole needle body capable of carrying medicine by mass. The medicine is mechanically mixed in the shape memory polymer of the matrix material of the shape memory needle body 1 during preparation. The shape memory needle body 1 has biocompatibility and biodegradability. Has no inflammatory effect and good compatibility with the medicine.
The shape memory needle body 1 performs rapid shape recovery behavior at the temperature of 40-60 ℃, and recovers to the initial shape after 10-60 s. The diameter of the shape memory needle body 1 is 0.4-0.6mm, when the temperature is higher than the Tg of the material, the shape memory needle body 1 can stretch, and the diameter of the shape memory needle body 1 after stretching forming is 0.2-0.4 mm. The length of the shape memory needle body 1 is 10-15mm, and the length of the shape memory needle body 1 after stretching forming is 15-20 mm.
The shape memory needle body 1 is driven by heat or infrared light.
The shape-memory needle body 1 is shaped by heat or infrared light. The shaping mode of the shape memory needle body 1 can be body temperature or electric heating blowing heating.
The shape of the shape memory needle body 1 after shaping is spiral, annular or triangular. The user can shape according to the preference of the user, and can purchase a pendant to be hung on the earring to play a decorative role. The specific shaping mode of the shape memory needle body 1 is that the tip of the shape memory needle body 1 is soaked in warm water with the temperature of 45 ℃ for 1min and then taken out, then the tip of the shape memory needle body 1 is bent into a spiral shape, the external constraint is removed after the external constraint is kept for 1min, and then the shaping process can be completed. After the affected part is healed, if the needle body needs to be taken down, the specific operation mode is that the shape memory needle body 1 is flushed for about 1min by warm water with the temperature of 45 ℃, and the shape memory needle body 1 is quickly restored to the original shape. In order to take out the shape memory needle body 1 conveniently, the shape memory needle body 1 can be immediately stretched and shaped, after shaping is finished, the diameter of the shape memory needle body 1 can be reduced, the shape memory needle body 1 can be taken out from an ear hole conveniently, and pain of a patient is relieved. When the shape memory needle body 1 is worn next time, the shape memory needle body 1 can return to the initial diameter after being soaked in warm water with the temperature of 45 ℃ for 1 min.
When the ear hole is punched, the needle body base 2 is fixed on the ear hole punching gun, after the punching, the shape memory needle body 1 penetrates through the human tissue, and the needle body base 2 is separated from the ear hole punching gun.
The wearing person can be conveniently and quickly worn and taken off the shape memory needle body 1 when blowing hair.
The shape memory needle body 1 is made of shape memory polyurethane. Polyurethanes are composed of soft segments with a low thermal transition temperature and hard segments with a high thermal transition temperature. The difference of the molecular structures of the soft segment and the hard segment causes the thermodynamic incompatibility, the SMPU molecules generate microphase separation, and the thermal transition temperature between the two phases is different, so that the polyurethane has the shape memory property at a certain temperature. The glass transition temperature was 45 ℃ and the time taken to return to the original shape under these conditions was 60 seconds. The shape memory needle body 1 is not limited to ear nails and ear rings, and can also be used for ornaments such as lip nails, tongue nails, nose rings, umbilical nails and the like.
The structure of the drug-loaded ornament which is worn through the skin and is based on the shape memory polymer is not limited to the specific structure described in each embodiment, and can also be a reasonable combination of the characteristics described in each embodiment.
Claims (4)
1. A drug-loaded ornament which is worn through skin and based on shape memory polymer is characterized by comprising a shape memory needle body (1), a needle body base (2) and an ornament (3); the shape memory needle body (1) and the ornament (3) are respectively fixed on two sides of the needle body base (2), the shape memory needle body (1) is made of a shape memory polymer material, the shape memory polymer material comprises one or more of shape memory polyurethane, shape memory polylactic acid, aliphatic polyester, polyisoprene or polylactide, the medicine carried by the shape memory needle body (1) is one or two of antibacterial medicine and anti-inflammatory medicine, and the medicine is mechanically mixed in the shape memory polymer of a base material of the shape memory needle body (1) during preparation;
the shape memory needle body (1) is molded by extrusion molding, injection molding, compression molding or casting molding.
2. The transdermal drug-loaded ornament based on shape memory polymer according to claim 1, characterized in that the shape memory needle (1) performs a rapid shape recovery action at a temperature of 40-60 ℃ and returns to the original shape after 10-60 s.
3. The drug-loaded ornament worn through the skin based on shape memory polymer as claimed in claim 1, wherein the shape memory needle (1) is driven by heat or infrared light.
4. The drug-loaded ornament worn through skin based on shape memory polymer as claimed in claim 1, wherein the shape memory needle body (1) is shaped by heat or infrared light.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201810495286.3A CN108618285B (en) | 2018-05-22 | 2018-05-22 | Drug-loaded ornament worn through skin based on shape memory polymer |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201810495286.3A CN108618285B (en) | 2018-05-22 | 2018-05-22 | Drug-loaded ornament worn through skin based on shape memory polymer |
Publications (2)
Publication Number | Publication Date |
---|---|
CN108618285A CN108618285A (en) | 2018-10-09 |
CN108618285B true CN108618285B (en) | 2020-06-23 |
Family
ID=63693968
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201810495286.3A Active CN108618285B (en) | 2018-05-22 | 2018-05-22 | Drug-loaded ornament worn through skin based on shape memory polymer |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN108618285B (en) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE102019002261B4 (en) * | 2019-03-29 | 2023-07-27 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Piece of jewelery with a decorative molding made of polymeric materials and a set of jewelery with such a piece of jewellery |
CN110192913B (en) | 2019-06-13 | 2020-11-20 | 程波 | Nose nail for perforation and perforation device |
CN113081198A (en) * | 2021-04-16 | 2021-07-09 | 曾标 | Painless slow-expansion puncture needle and use method thereof |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR20090033736A (en) * | 2007-10-01 | 2009-04-06 | 김창현 | Ears-bored earring using shape memory alloy |
CN201085658Y (en) * | 2007-10-19 | 2008-07-16 | 张惠玲 | Injection trocar |
CN101361977A (en) * | 2008-09-28 | 2009-02-11 | 西南交通大学 | Drug-loaded biodegradable shape memory macromolecule composite material and preparation method thereof |
FR2936686A1 (en) * | 2008-10-02 | 2010-04-09 | Alain Hautcoeur | Jewellery e.g. bracelet, has body made of shape memory alloy, and closing or locking device completely closing or locking jewellery without clasp, where deformability of alloy permits thin band to be deformable to accommodate cabochon |
CN201806051U (en) * | 2010-09-30 | 2011-04-27 | 王忠善 | Ear nails |
CN102319486A (en) * | 2011-06-21 | 2012-01-18 | 四川大学 | The shape memory of focus supersonic Synchronization Control shape memory drug-carrying polymer and the method for drug release |
CN103340745A (en) * | 2013-06-14 | 2013-10-09 | 成都御饰国康科技有限公司 | Medical health-care earring with good effect |
JP3187872U (en) * | 2013-10-08 | 2013-12-19 | 大▲崎▼学 | Ornaments and ornament kits |
CN104740688B (en) * | 2015-03-19 | 2017-04-12 | 西南交通大学 | Preparation method of microsphere close-packed shape memory porous scaffold |
CN206423659U (en) * | 2016-04-29 | 2017-08-22 | 上海市第十人民医院 | Ear nail |
-
2018
- 2018-05-22 CN CN201810495286.3A patent/CN108618285B/en active Active
Also Published As
Publication number | Publication date |
---|---|
CN108618285A (en) | 2018-10-09 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CN108618285B (en) | Drug-loaded ornament worn through skin based on shape memory polymer | |
CN111432750A (en) | Hair transplant and medical safety features including enhanced anchoring | |
CN201098221Y (en) | Plastic belt for plastic surgery | |
CN101390805B (en) | Long-acting auricular point invisible needle granule therapy plaster | |
CN2233204Y (en) | Health pearl towel used to cover pillow | |
CN213217909U (en) | Nose prosthesis structure for plastic and beauty treatment | |
CN103181855A (en) | Acupuncture point therapeutic tape | |
JP2009084722A (en) | Wig | |
JP2009084772A (en) | Wig | |
KR200413428Y1 (en) | Personal ornaments | |
CN108607115A (en) | A kind of M lips shaping suture | |
CN220002734U (en) | Microneedle face neck cover | |
Khilnani et al. | Clinical and demographic profile of cases requiring ear lobe repair in North Gujarat | |
CN203089853U (en) | Acupuncture point treatment belt | |
CN203953877U (en) | Transplantation enters the wig of scalp | |
CN2778038Y (en) | Bracelets | |
CN201085696Y (en) | Simple cap with tooth-plant function | |
KR200494767Y1 (en) | Hair thickening type partial wig set | |
CN201157533Y (en) | Long-acting auricular point invisible needle particle treating plaster | |
KR200271217Y1 (en) | Jewelry is made from gold, gold alloy, silver, silver alloy, brass, bronze and the others metal alloy using magnet | |
JP3144390U (en) | Acupuncture point sticking plaster | |
KR101095791B1 (en) | hair implanting method for manufacturing wig | |
CN2421033Y (en) | Health bra | |
CN207693093U (en) | A kind of fastening-type ear nail | |
CN2183680Y (en) | Hairs for hair-weaving |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PB01 | Publication | ||
PB01 | Publication | ||
SE01 | Entry into force of request for substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
GR01 | Patent grant | ||
GR01 | Patent grant |