CN108593904A - Detector and detection method - Google Patents
Detector and detection method Download PDFInfo
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- CN108593904A CN108593904A CN201810721545.XA CN201810721545A CN108593904A CN 108593904 A CN108593904 A CN 108593904A CN 201810721545 A CN201810721545 A CN 201810721545A CN 108593904 A CN108593904 A CN 108593904A
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- 238000001514 detection method Methods 0.000 title claims abstract description 133
- 238000000605 extraction Methods 0.000 claims abstract description 147
- 239000003153 chemical reaction reagent Substances 0.000 claims abstract description 88
- 230000035484 reaction time Effects 0.000 claims abstract description 43
- 238000012360 testing method Methods 0.000 claims abstract description 25
- 230000008021 deposition Effects 0.000 claims abstract description 22
- 238000005192 partition Methods 0.000 claims description 29
- 239000000284 extract Substances 0.000 claims description 27
- 239000003795 chemical substances by application Substances 0.000 claims description 4
- 238000003908 quality control method Methods 0.000 claims 1
- 238000007689 inspection Methods 0.000 abstract description 4
- 238000000151 deposition Methods 0.000 description 17
- 241000606161 Chlamydia Species 0.000 description 5
- 238000010586 diagram Methods 0.000 description 3
- 230000028327 secretion Effects 0.000 description 3
- 210000001124 body fluid Anatomy 0.000 description 2
- 239000010839 body fluid Substances 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 238000003825 pressing Methods 0.000 description 2
- 210000002700 urine Anatomy 0.000 description 2
- 229920000742 Cotton Polymers 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 235000013399 edible fruits Nutrition 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- PCHJSUWPFVWCPO-UHFFFAOYSA-N gold Chemical compound [Au] PCHJSUWPFVWCPO-UHFFFAOYSA-N 0.000 description 1
- 239000010931 gold Substances 0.000 description 1
- 229910052737 gold Inorganic materials 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
Classifications
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/00584—Control arrangements for automatic analysers
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Chemical & Material Sciences (AREA)
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- Urology & Nephrology (AREA)
- Hematology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Abstract
A kind of detector of present invention offer and detection method.The detector of the present invention carries out timing to the reaction time of the extraction time of sample and detection card respectively using extraction time control module with reaction time control module, promote the accuracy of timing, and then promote the accuracy of testing result, the detector is equipped with object carrying area, sample deposition, reagent rest area, sample extraction area, detection card reaction zone, extracting solution rest area simultaneously, classification placement can be carried out to all kinds of articles, avoid the occurrence of obscure, missing inspection situations such as, additionally it is possible to realize the check and tracking of testing result.Further, the present invention also provides a kind of detection methods, are realized using above-mentioned detector, can promote the accuracy and timeliness of testing result.
Description
Technical field
The present invention relates to detection technique field more particularly to a kind of detector and detection methods.
Background technology
Currently, the detection means or full manual inspection of Chlamydia detection sample (such as body fluid, urine secretion), do not have
Fixed detecting instrument, such detection method have the following disadvantages：1, the extraction time of sample needs manual time-keeping, and timing is not
Accurately, it be easy to cause that the sample extraction time is undesirable, influences the accuracy of testing result；2, the reaction time of detection card needs
Manual time-keeping is wanted, timing is inaccurate, causes the reaction time undesirable, influences the accuracy of testing result；3, extracts reagent
Without fixed position, it is easy to obscure；4, without fixed position, placement is in disorder for sample cell and extraction tube, be easy to cause detection mistake and leakage
Inspection；5, when addition sample extracting solution is reacted during detection blocks, detection card is without fixed position, in the inspection for reading multiple detection cards
It is susceptible to and obscures when surveying result；6, the check and tracking of testing result are difficult to realize.
Invention content
The purpose of the present invention is to provide a kind of detectors, can promote the accuracy of testing result.
The present invention also aims to provide a kind of detection method, the accuracy and timeliness of testing result can be promoted.
To realize the above goal of the invention, present invention firstly provides a kind of detectors, are applied to following detection method：It utilizes
Extracts reagent for a period of time, obtains sample extracting solution to sample extraction, is later added to sample extracting solution in detection card and anti-
After answering a period of time, testing result is read from detection card, when being equipped with extraction time control module with reacting in the detector
Between control module, the extraction time control module can carry out timing to the extraction time of sample, upon extracting between reach and set
After definite value, the extraction time control module sends out alarm, when the reaction time control module can be to the reaction of detection card
Between carry out timing, when reacted between reach setting value after, the reaction time control module sends out alarm.
Be equipped in the detector object carrying area, sample deposition, reagent rest area, sample extraction area, detection card reaction zone,
Extracting solution rest area；The object carrying area is used to place the detection object for including the detection card, empty extraction tube and accessory that do not break a seal
Product；The sample deposition is for placing the sample cell containing detected sample and the extraction tube added with extractant；It is described
Reagent rest area is for placing extracts reagent；The sample extraction area is used to place the extraction added with extracts reagent and sample
Pipe obtains sample extracting solution after extracting a period of time；The detection card reaction zone is reacted for placing detection card with being detected,
After adding sample extracting solution during detection blocks and reacting a period of time, there is testing result on detection card；The extracting solution is placed
Area is used for after being reacted during a part of sample extracting solution to be added to detection card, by the extraction containing remaining sample extracting solution
Pipe is positioned in the region, convenient to be checked detecting to stagger the time to be backed up to sample extracting solution.
The detector includes bottom plate, the side plate being connected with bottom plate, the first partition being respectively connected with bottom plate and side plate, institute
It states side plate and crosses an accommodating space with bottom plate, the accommodating space is divided into object carrying area and is detected with extraction by the first partition
Area；
The detector further includes corresponding to extraction detection zone to be set to the first partition and plate the upper surface of on side plate；Institute
State sample deposition, reagent rest area, sample extraction area, detection card reaction zone, extracting solution rest area, extraction time control mould
Block, reaction time control module are set in the top panel.
Multiple first through hole are equipped in the sample deposition of the top panel；It is equipped in the reagent rest area of the top panel
Multiple second through-holes；Multiple third through-holes are equipped in the sample extraction area of the top panel；The extracting solution of the top panel is placed
Multiple fourth holes are equipped in area；It is equipped with multiple detections card in the detection card reaction zone of the top panel and places groove.
The extraction time control module includes the first module, the second module, the first timer；First module and the
Two modules are respectively positioned on top panel, and the first button and the first alarm lamp are equipped in first module, is set in second module
There are the first display screen and the first loud speaker；
The reaction time control module includes third module, the 4th module, the second timer, the third module and the
Four modules are respectively positioned on top panel, and the second button and the second alarm lamp are equipped in the third module, is set in the 4th module
There are second display screen and the second loud speaker.
Pass through screw connection between the top panel and first partition and side plate.
In the object carrying area be equipped with second partition, the second partition respectively with the bottom plate, side plate and first partition phase
Even, the object carrying area is divided into the first object carrying area and the second object carrying area, first object carrying area and second by the second partition
Object carrying area is groove structure.
The reagent rest area includes the first reagent rest area and the second reagent rest area, first reagent rest area with
Multiple second through-holes are equipped in second reagent rest area.
The alignment placement in each region is as follows in the top panel：
Orthogonal first direction X and second direction Y, the object carrying area and extraction detection zone are defined in top panel
It is arranged in order along first direction X；
In the object carrying area, Y is arranged in order in a second direction with the second object carrying area for first object carrying area；
In the extraction detection zone, the sample deposition, reagent rest area, sample extraction area and extraction time control mould
Y is arranged in order as first row block in a second direction, wherein the sample extraction area is with extraction time control module along first direction
X is arranged in order；Y is arranged in order in a second direction for the extracting solution rest area, detection card reaction zone and reaction time control module
For secondary series, wherein the detection card reaction zone is arranged in order with reaction time control module along first direction X；Described first
Row are arranged close to the object carrying area, and are spaced apart by first partition with the object carrying area.
The present invention also provides a kind of detection methods, include the following steps：
Step 1 provides detector as described above, sample, extracts reagent, detection card；
Step 2 extracts the sample using the extracts reagent, is controlled using extraction time in extraction process
Module controls extraction time, obtains sample extracting solution；
Sample extracting solution is added in detection card and reacts by step 3, utilizes the reaction time to control during the reaction
Module controls the reaction time, after reaction, is read out to the testing result on detection card.
Beneficial effects of the present invention：The detector of the present invention, can be to sample by the way that extraction time control module is arranged
Extraction time is accurately controlled, prevented because sample extraction time inaccurately caused by testing result mistake；By setting
Reaction time control module is set, the reaction time row of detection card can be accurately controlled, prevented because when detecting the reaction of card
Between it is inaccurate caused by testing result mistake；By the way that object carrying area is arranged, the placement of detection card and extraction tube is facilitated, is effectively prevent
The loss of detection card and extraction tube；By the way that sample deposition is arranged, facilitates the orderly placement of sample cell, prevent to place because of sample cell
Mistake is detected caused by disorder；By the way that reagent rest area is arranged, facilitate the management of extracts reagent and orderly places, avoid due to examination
Agent detects mistake caused by obscuring；By the way that sample extraction area is arranged, the orderly of extraction tube is facilitated to place and can be to extraction tube
Extraction time carries out accurate timing, avoids wrong due to being detected caused by the placement of extraction tube confusion and extraction time timing error
Accidentally；Card reaction zone is detected by setting, the orderly placement of detection card is facilitated, can realize the clear interpretation of testing result, it is convenient
The inquiry and check of testing result prevent to detect mistake caused by detection card placement is in disorder；By the way that extracting solution rest area is arranged,
Sample extracting solution can be backed up, it is convenient to be checked and tracked detecting to stagger the time.In addition, the detector knot of the present invention
Structure is simple, low manufacture cost, and easy to use, is suitable for the various detections of clinical examination and scientific research field, can drop significantly
The risk of errors of low artificial detection, and realize quickly detection.
Description of the drawings
In order to illustrate the technical solution of the embodiments of the present invention more clearly, below will be to needed in the embodiment attached
Figure is briefly described, it should be understood that the following drawings illustrates only certain embodiments of the present invention, therefore is not construed as pair
The restriction of the scope of the invention.
Fig. 1 is the dimensional structure diagram of the detector of the present invention；
Fig. 2 is the schematic top plan view of the detector of the present invention；
Fig. 3 is the flow chart of the detection method of the present invention.
Main element symbol description：
11- bottom plates；12- side plates；121- power switches；122- power supply indicators；123- power cords；124- attaching plugs；
13- first partitions；16- second partitions；The object carrying areas 21-；22- extracts detection zone；30- top panels；The sample depositions 31-；32- is tried
Agent rest area；The first reagents of 321- rest area；The second reagents of 322- rest area；33- sample extractions area；34- extracting solutions rest area；
35- detects card reaction zone；41- first through hole；The second through-holes of 42-；43- third through-holes；44- fourth holes；45- detection cards are placed
Groove；51- extraction time control modules；52- reaction time control modules；The first buttons of 61-；The first alarm lamps of 63-；64-
One display screen；The first loud speakers of 65-；The first modules of 71-；The second modules of 72-；73- third modules；The 4th modules of 74-；81-
Two buttons；The second alarm lamps of 83-；84- second display screens；The second loud speakers of 85-.
Specific implementation mode
In the following, in conjunction with attached drawing, the present invention will be described in detail.
It please refers to Fig.1 and Fig. 2, the present invention provides a kind of detector, be applied to following detection method：Utilize extracts reagent
For a period of time to sample extraction, when obtaining sample extracting solution, sample extracting solution is added in detection card later and reacting one section
Between after, read testing result from detection card, extraction time control module 51 be equipped in the detector and is controlled with the reaction time
Module 52, the extraction time control module 51 can to the extraction time of sample carry out timing, upon extracting between reach setting
After value, the extraction time control module 51 sends out alarm, and operating personnel is reminded to stop extracting sample, when the reaction
Between control module 52 can carry out timing to the reaction time of detection card, when reacted between reach setting value after, when the reaction
Between control module 52 send out alarm, remind operating personnel to be read out the testing result on detection card.
Specifically, being equipped with object carrying area 21, sample deposition 31, reagent rest area 32, sample extraction area in the detector
33, detection card reaction zone 35, extracting solution rest area 34；It includes the detection card not broken a seal that the object carrying area 21, which is used to place, empty
The detection article of extraction tube and accessory；The sample deposition 31 is for placing the sample cell containing detected sample and adding
Added with the extraction tube of extractant；The reagent rest area 32 is for placing extracts reagent；The sample extraction area 33 is for placing
Extraction tube added with extracts reagent and sample obtains sample extracting solution after extracting a period of time；The detection card reaction zone 35
Block to be detected reaction for placing to detect, after adding sample extracting solution during detection blocks and reacting a period of time, detects card
On there is testing result；The extracting solution rest area 34 is used in a part of sample extracting solution to be added to detection card carry out anti-
Extraction tube containing remaining sample extracting solution is positioned in the region by Ying Hou, to be backed up to sample extracting solution, is conveniently existed
It detects to stagger the time and be checked.
Specifically, the detector includes bottom plate 11, the side plate being connected with bottom plate 11 12, distinguishes with bottom plate 11 and side plate 12
Connected first partition 13, the side plate 12 and bottom plate 11 cross an accommodating space, and the first partition 13 is by the accommodating sky
Between be divided into object carrying area 21 with extraction detection zone 22；
The detector further include correspond to extraction detection zone 22 be set to the first partition 13 with it is upper on side plate 12
Panel 30；The sample deposition 31, reagent rest area 32, sample extraction area 33, detection card reaction zone 35, extracting solution rest area
34, extraction time control module 51, reaction time control module 52 are set in the top panel 30.
Specifically, being equipped with multiple first through hole 41, the first through hole 41 in the sample deposition 31 of the top panel 30
In can place sample cell with added with extracts reagent extraction tube；Multiple the are equipped in the reagent rest area 32 of the top panel 30
Two through-holes 42 can place extracts reagent in second through-hole 42；It is equipped in the sample extraction area 33 of the top panel 30 multiple
Third through-hole 43 can place the extraction tube added with extracts reagent and sample in the third through-hole 43；The top panel 30
It detects and is equipped with multiple detections card placement groove 45 in card reaction zone 35, the detection card places the depth of groove 45 slightly larger than described in
The thickness of card is detected, the shape that the detection card places groove 45 is identical as the shape of detection card, and the detection card is placed
The area of groove 45 is slightly larger than the area or same that the detection blocks, to facilitate detection card to keep flat and be sticked in detection
Card is placed in groove 45, and the position of detection card is kept to fix during the reaction；The extracting solution rest area 34 of the top panel 30
In be equipped with multiple fourth holes 44, the extraction tube containing remaining sample extracting solution can be placed in the fourth hole 44.
Groove 45 is placed specifically, being equipped in the detection card reaction zone 35 of the top panel 30 and being used to form multiple detection cards
Grid-shaped baffle plate；Can be provided with or without in the sample deposition 31 of the top panel 30 will be between multiple first through hole 41
The grid-shaped baffle plate separated；It can be provided with or without in the sample extraction area 33 of the top panel 30 by multiple third through-holes
43 grid-shaped baffle plates spaced apart；Can be provided with or without in the sample extracting solution rest area 34 of the top panel 30 will be more
The grid-shaped baffle plate spaced apart of a fourth hole 44.
Specifically, the extraction time control module 51 include the first module 71, the second module 72, the first timer (not
Diagram), first module, 71 and second module 72 is respectively positioned on top panel 30, and the first button is equipped in first module 71
61 and first alarm lamp 63, the first display screen 64 and the first loud speaker 65 are equipped in second module 72.
After pressing the first button 61, the first timer starts to carry out timing to extraction time, is shown on the first display screen 64
Timing time, after timing time reaches the extraction time of setting, the first loud speaker 65 carries out audible alarm, the first alarm lamp 63
Carry out light warning.Specifically, operating personnel can also set extraction time on the first display screen 64.
Specifically, the reaction time control module 52 include third module 73, the 4th module 74, the second timer (not
Diagram), 73 and the 4th module 74 of the third module is respectively positioned on top panel 30, and the second button is equipped in the third module 73
81 and second alarm lamp 83, second display screen 84 and the second loud speaker 85 are equipped in the 4th module 74.
After pressing the second button 81, the second timer starts to carry out timing, second display screen to the reaction time of detection card
Timing time is shown on 84, after timing time reaches the reaction time of setting, the second loud speaker 85 progress audible alarm, second
Alarm lamp 83 carries out light warning.Specifically, operating personnel can also set the reaction time on second display screen 84.
As shown in Figure 1, in a preferred embodiment of the application detector, the bottom plate 11 is quadrangle, the side plate
12 quantity is four, is connected respectively with the four edges of the bottom plate 11.Preferably, the bottom plate 11 is rectangle.
Preferably, by screw connection (not shown) between the top panel 30 and first partition 13 and side plate 12, thus
In use for some time, top panel 30 can be removed, top panel 30, bottom plate 11, first partition 13, side plate 12 is carried out clearly
It washes.
Specifically, the side plate 12 is equipped with power switch 121 and power supply indicator 122；The detector further include with
The attaching plug 124 side plate 12 connected power cord 123 and be connected far from 12 one end of the side plate with power cord 123.
The case where being used as Chlamydia detector below for detector of the invention is described in detail：
When the detector of the present invention is used as Chlamydia detector, the detection card is Chlamydia gold mark detection card, described to carry
It includes the first reagent and the second reagent to take reagent, when preparing sample extracting solution, need to add successively in the sample the first reagent and
Second reagent extracts.
In the object carrying area 21 be equipped with second partition 16, the second partition 16 respectively with the bottom plate 11, side plate 12 and
First partition 13 is connected, and the object carrying area 21 is divided into the first object carrying area 211 and the second object carrying area by the second partition 16
212, first object carrying area, 211 and second object carrying area 212 is groove structure, and first object carrying area 211 is for placing not
The detection card in Kaifeng, second object carrying area 212 are used to place empty extraction tube and other accessories.
The reagent rest area 32 includes the first reagent rest area 321 and the second reagent rest area 322, first reagent
It is equipped with multiple second through-holes 42 in rest area 321 and the second reagent rest area 322, the of first reagent rest area 321
Two through-holes 42 are for placing the first reagent, and the second through-hole 42 of second reagent rest area 322 is for placing the second reagent.
In first module 71 of the extraction time control module 51, the quantity of first button 61 is two, respectively
Extraction timing for starting the first reagent and the extraction timing of the second reagent；The quantity of first timer is two,
It is respectively used to extraction timing and the extraction timing of the second reagent of the first reagent.
The alignment placement in each region is as follows in the top panel 30：
Orthogonal first direction X and second direction Y are defined in top panel 30, the object carrying area 21 is examined with extraction
Area 22 is surveyed to be arranged in order along first direction X；
In the object carrying area 21, Y is arranged in order in a second direction with the second object carrying area 212 for first object carrying area 211；
In the extraction detection zone 22, when the sample deposition 31, reagent rest area 32, sample extraction area 33 are with extraction
Between control module 51 Y is arranged in order as first row in a second direction, wherein the sample extraction area 33 and extraction time control mould
Block 51 is arranged in order along first direction X；The extracting solution rest area 34, detection card reaction zone 35 and reaction time control module 52
Y is arranged in order as secondary series in a second direction, wherein the detection card reaction zone 35 is with reaction time control module 52 along first
Direction X is arranged in order；The first row is arranged close to the object carrying area 21, and passes through first partition 13 with the object carrying area 21
It is spaced apart；
In the reagent rest area 32, first reagent rest area 321 and the second reagent rest area 322 are along first direction
X is arranged in order.
Specifically, in the sample extraction area 33, the multiple third through-hole 43 is arranged as several rows along first direction X, often
The end of a line is set there are one extraction time control module 51, which is responsible for the to being positioned over the row
The extraction time of extraction tube in three through-holes 43 is controlled.Further, Y is arranged the multiple third through-hole 43 in a second direction
It is classified as ordered series of numbers.
In the extraction time control module 51, first module 71 is arranged with the second module 72 along first direction X successively
Row, in first module 71, Y is arranged in order in a second direction for first alarm lamp 63, the first button 61, two of which the
One button 61 is arranged as a line along first direction X, in second module 72, first display screen 64, the first loud speaker 65
Y is arranged in order in a second direction.
Specifically, in the detection card reaction zone 35, the multiple detection card is placed groove 45 and is arranged as along first direction X
Several rows, the end per a line is set there are one reaction time control module 52, which is responsible for being positioned over
The reaction time that the detection card of the row places the detection card in groove 45 is controlled.Further, the multiple detection card is put
Setting groove 45, Y is arranged as ordered series of numbers in a second direction.
In the reaction time control module 52, the third module 73 is arranged with the 4th module 74 along first direction X successively
It arranges, in the third module 73, Y is arranged in order in a second direction for second alarm lamp 83, the second button 81, the 4th mould
In block 74, Y is arranged in order in a second direction for the second display screen 84, the second loud speaker 85.
Specifically, in the sample deposition 31, the multiple first through hole 41 is arranged as several rows along first direction X, edge
Second direction Y is arranged as ordered series of numbers；In the sample extracting solution rest area 34, the multiple fourth hole 44 is arranged along first direction X
It is classified as several rows, Y is arranged as ordered series of numbers in a second direction.
The detector of the present invention can carry out the extraction time of sample accurate by the way that extraction time control module 51 is arranged
Control, prevented because sample extraction time inaccurately caused by testing result mistake；Mould is controlled by the way that the reaction time is arranged
Block 52 can accurately control the reaction time row for detecting card, prevent because the reaction time of detection card is inaccurately caused
Testing result mistake；By the way that object carrying area 21 is arranged, the placement for detecting card and extraction tube is facilitated, detection is effectively prevent to block and extract
The loss of pipe；By the way that sample deposition 31 is arranged, facilitates the orderly placement of sample cell, prevent caused by sample cell placement is in disorder
Detect mistake；By the way that reagent rest area 32 is arranged, facilitate the management of extracts reagent and orderly places, avoids obscuring due to reagent and make
At detection mistake；By the way that sample extraction area 33 is arranged, facilitate extraction tube it is orderly place and can be to the extraction of extraction tube when
Between carry out accurate timing, avoid due to extraction tube confusion place and extraction time timing error caused by detect mistake；Pass through
Setting detection card reaction zone 35, facilitates the orderly placement of detection card, can realize the clear interpretation of testing result, detection is facilitated to tie
The inquiry and check of fruit prevent to detect mistake caused by detection card placement is in disorder；It, can by the way that extracting solution rest area 34 is arranged
Sample extracting solution is backed up, it is convenient to be checked and tracked detecting to stagger the time.In addition, the detector structure letter of the present invention
It is single, low manufacture cost, and it is easy to use, it is suitable for the various detections of clinical examination and scientific research field, people can be substantially reduced
The risk of errors of work detection, and realize quickly detection.
Referring to Fig. 3, being based on above-mentioned detector with Fig. 2 refering to fig. 1 simultaneously, the application also provides a kind of detection method, wraps
Include following steps：
Step 1 provides above-mentioned detector, sample, extracts reagent, detection card.
Step 2 extracts the sample using the extracts reagent, is controlled using extraction time in extraction process
Module 51 controls extraction time, obtains sample extracting solution.
Sample extracting solution is added in detection card and reacts by step 3, utilizes the reaction time to control during the reaction
Module 52 controls the reaction time, after reaction, is read out to the testing result on detection card.
Since the concrete structure of the detector being described in detail above, details are not described herein again.
The detection method of the present invention is described in detail by taking the detection method of Chlamydia as an example below：
In the step 1, the sample is the cotton test paper for being attached with secretion, and the secretion is body fluid or urine, institute
Sample is stated to be placed in sample cell；The extracts reagent includes the first reagent and the second reagent, is respectively placed in first examination
In second through-hole 42 of agent rest area 321 and the second through-hole 42 of second reagent rest area 322.
The step 1 further includes：Empty extraction tube is provided, the first reagent is added in the extraction tube, the will be added with
The extraction tube number of being numbered with of one reagent is arranged in order in the first through hole 41 of sample deposition 31；By the sample cell containing sample
On the number of being numbered be arranged in order in the first through hole 41 of sample deposition 31.
The step 2 includes：
Step 21 takes out sample from sample cell, is respectively put into order in the extraction tube added with the first reagent, will
Extraction tube added with the first reagent and sample is transferred in the third through-hole 43 in sample extraction area 33, is controlled using extraction time
Module 51 controls the extraction time of the first reagent.
Specifically, the step of being controlled the extraction time of the first reagent using extraction time control module 51 includes：
First button 61 in left side is pressed, the extraction time of first the first reagent of timer pair carries out timing, after reaching setting time, the
One loud speaker 65 carries out audible alarm, and the first alarm lamp 63 carries out light warning, and the extraction step of the first reagent terminates.
Step 22 adds the second reagent in extraction tube, the extraction using extraction time control module 51 to the second reagent
Time is controlled, remaining in the extraction tube by sample from taking out and put back in sample cell in extraction tube after extraction
Liquid is sample extracting solution.
Specifically, the step of being controlled the extraction time of the second reagent using extraction time control module 51 includes：
First button 61 on right side is pressed, the extraction time of first the second reagent of timer pair carries out timing, after reaching setting time, the
One loud speaker 65 carries out audible alarm, and the first alarm lamp 63 carries out light warning, and the extraction step of the second reagent terminates.
Specifically, in the step 3, after sample extracting solution is added in detection card, remaining sample extracting solution will be contained
Extraction tube be put into the fourth hole 44 of extracting solution rest area 34.
Specifically, in the step 3, the step of being controlled detection time using reaction time control module 52, is wrapped
It includes：The second button 81 is pressed, the second timer carries out timing to the detection time of detection card, and after reaching setting time, second raises
Sound device 85 carries out audible alarm, and the second alarm lamp 83 carries out light warning, and the reaction time for detecting card terminates, at this time reply detection
Testing result on card is read out.
The detection method of the present invention is realized using present invention detector above-mentioned, can substantially reduce the mistake of artificial detection
Risk, and realize quickly detection.
The foregoing is merely the preferable implementation examples of the present invention, are not intended to limit the invention, all the present invention's
Within spirit and principle, any modification, equivalent replacement, improvement and so on should all be included in the protection scope of the present invention.
Claims (10)
1. a kind of detector, which is characterized in that be equipped with extraction time control module in the detector and control mould with the reaction time
Block, the extraction time control module can to the extraction time of sample carry out timing, upon extracting between reach setting value after, institute
It states extraction time control module and sends out alarm, the reaction time control module can count the reaction time of detection card
When, when reacted between reach setting value after, the reaction time control module sends out alarm.
2. detector as described in claim 1, which is characterized in that be equipped with object carrying area, sample deposition, examination in the detector
Agent rest area, sample extraction area, detection card reaction zone, extracting solution rest area；It includes not breaking a seal that the object carrying area, which is used to place,
The detection article of detection card, empty extraction tube and accessory；The sample deposition is for placing the sample containing detected sample
Quality control and extraction tube added with extractant；The reagent rest area is for placing extracts reagent；It uses in the sample extraction area
In extraction tube of the placement added with extracts reagent and sample；The detection card reaction zone is anti-to be detected for placing detection card
It answers；The extracting solution rest area is used for after being reacted during a part of sample extracting solution to be added to detection card, will be contained surplus
The extraction tube of remaining sample extracting solution is positioned in the region, to be backed up to sample extracting solution.
3. detector as claimed in claim 2, which is characterized in that the detector include bottom plate, the side plate being connected with bottom plate,
The first partition being respectively connected with bottom plate and side plate, the side plate and bottom plate cross an accommodating space, and the first partition is by institute
It states accommodating space and is divided into object carrying area and extraction detection zone；
The detector further includes corresponding to extraction detection zone to be set to the first partition and plate the upper surface of on side plate；The sample
It is product rest area, reagent rest area, sample extraction area, detection card reaction zone, extracting solution rest area, extraction time control module, anti-
Time control module is answered to be set in the top panel.
4. detector as claimed in claim 3, which is characterized in that be equipped with multiple first in the sample deposition of the top panel
Through-hole；Multiple second through-holes are equipped in the reagent rest area of the top panel；It is equipped in the sample extraction area of the top panel more
A third through-hole；Multiple fourth holes are equipped in the extracting solution rest area of the top panel；The detection card of the top panel reacts
It is equipped with multiple detections card in area and places groove.
5. detector as claimed in claim 3, which is characterized in that the extraction time control module includes the first module, the
Two modules, the first timer；First module is respectively positioned on the second module on top panel, and first is equipped in first module
Button and the first alarm lamp are equipped with the first display screen and the first loud speaker in second module；
The reaction time control module includes third module, the 4th module, the second timer, the third module and the 4th mould
Block is respectively positioned on top panel, and the second button and the second alarm lamp are equipped in the third module, equipped with the in the 4th module
Two display screens and the second loud speaker.
6. detector as claimed in claim 3, which is characterized in that pass through spiral shell between the top panel and first partition and side plate
Silk connection.
7. detector as claimed in claim 3, which is characterized in that in the object carrying area be equipped with second partition, described second every
Plate is connected with the bottom plate, side plate and first partition respectively, and the object carrying area is divided into the first object carrying area by the second partition
With the second object carrying area, first object carrying area and the second object carrying area are groove structure.
8. detector as claimed in claim 4, which is characterized in that the reagent rest area includes the first reagent rest area and the
It is equipped with multiple second through-holes in two reagent rest areas, first reagent rest area and the second reagent rest area.
9. detector as claimed in claim 3, which is characterized in that the alignment placement in each region is as follows in the top panel：
Define orthogonal first direction X and second direction Y in top panel, the object carrying area and extraction detection zone are along the
One direction X is arranged in order；
In the object carrying area, Y is arranged in order in a second direction with the second object carrying area for first object carrying area；
In the extraction detection zone, the sample deposition, reagent rest area, sample extraction area and extraction time control module edge
Second direction Y is arranged in order as first row, wherein the sample extraction area and extraction time control module along first direction X according to
Secondary arrangement；Y is arranged in order in a second direction is for the extracting solution rest area, detection card reaction zone and reaction time control module
Two row, wherein the detection card reaction zone is arranged in order with reaction time control module along first direction X；The first row leans on
The nearly object carrying area setting, and be spaced apart by first partition with the object carrying area.
10. a kind of detection method, which is characterized in that include the following steps：
Step 1, offer detector as claimed in any one of claims 1-9 wherein, sample, extracts reagent, detection card；
Step 2 extracts the sample using the extracts reagent, and extraction time control module is utilized in extraction process
Extraction time is controlled, sample extracting solution is obtained；
Sample extracting solution is added in detection card and reacts by step 3, utilizes reaction time control module during the reaction
Reaction time is controlled, after reaction, the testing result on detection card is read out.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201810721545.XA CN108593904B (en) | 2018-06-29 | 2018-06-29 | Detector and detection method |
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| CN201810721545.XA CN108593904B (en) | 2018-06-29 | 2018-06-29 | Detector and detection method |
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| CN202605774U (en) * | 2012-06-19 | 2012-12-19 | 周媛媛 | Traditional Chinese medicine water-soluble component coarse extractor |
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| CN103941032A (en) * | 2014-05-06 | 2014-07-23 | 北京中勤世帝生物技术有限公司 | Automatic detector for biological samples |
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| CN206408198U (en) * | 2017-01-09 | 2017-08-15 | 山东吉田香料股份有限公司 | A kind of spices squeezes extraction element |
| CN209028083U (en) * | 2018-06-29 | 2019-06-25 | 广东省中医院（广州中医药大学第二附属医院、广州中医药大学第二临床医学院、广东省中医药科学院） | Detector |
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2018
- 2018-06-29 CN CN201810721545.XA patent/CN108593904B/en active Active
Patent Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN202605774U (en) * | 2012-06-19 | 2012-12-19 | 周媛媛 | Traditional Chinese medicine water-soluble component coarse extractor |
| CN103344638A (en) * | 2013-07-05 | 2013-10-09 | 深圳奥萨制药有限公司 | Semi-automatic in-vitro detection equipment and method for measuring HCY (Homocysteine) by adopting colorimetric method |
| CN103941032A (en) * | 2014-05-06 | 2014-07-23 | 北京中勤世帝生物技术有限公司 | Automatic detector for biological samples |
| WO2016209773A1 (en) * | 2015-06-22 | 2016-12-29 | Dots Technology Corp. | Improved assays and methods for allergen detection |
| US20180188139A1 (en) * | 2015-06-22 | 2018-07-05 | Dots Technology Corp. | Improved assays and methods for allergen detection |
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| CN108593904B (en) | 2024-10-01 |
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