CN108578901A - A kind of millimeter wave synthetic therapeutic apparatus of phase stabilization - Google Patents
A kind of millimeter wave synthetic therapeutic apparatus of phase stabilization Download PDFInfo
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- CN108578901A CN108578901A CN201810074208.6A CN201810074208A CN108578901A CN 108578901 A CN108578901 A CN 108578901A CN 201810074208 A CN201810074208 A CN 201810074208A CN 108578901 A CN108578901 A CN 108578901A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/02—Radiation therapy using microwaves
- A61N5/022—Apparatus adapted for a specific treatment
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- Optical Modulation, Optical Deflection, Nonlinear Optics, Optical Demodulation, Optical Logic Elements (AREA)
Abstract
The invention discloses a kind of millimeter wave synthetic therapeutic apparatus of phase stabilization, millimeter wave generator including phase compensation and coat its shell, the millimeter wave is drawn by millimeter waveguide pipe, waveguide nozzle alignment tumor cell tissue position or the acupuncture point of corresponding organ is allowed to be oriented irradiation, waveguide is arc or semicircular smooth tube structure for that can be placed in intraluminal end face blind end, and infra-red radiation disk and bass transmitter are also combined on waveguide.The present invention is drawn by millimeter waveguide pipe, waveguide nozzle alignment tumor cell tissue position or the acupuncture point of corresponding organ is allowed to be oriented irradiation, it is wrapped up in around human body around a millimeter wave reflection band, a millimeter wave energy is set to focus in tumor cell tissue, interfere the charged ion and iron particle in tumor tissues, to inhibit the growth of tumour, the frequency and intensity for the millimeter wave that selected phase is stablized, the growth of tumour cell in the case where not killing normal cell, can be inhibited or promote its apoptosis.
Description
Technical field
The present invention relates to millimeter-wave technology field more particularly to a kind of millimeter wave synthetic therapeutic apparatus of phase stabilization.
Background technology
Tumour is to endanger the primary disease of human life.The treatment of tumour relies primarily on operation, chemotherapy, radiotherapy and support
Therapy uses biological therapy, Chinese traditional treatment and other methods under a few cases.Currently, the various frequency spectrums clinically applied are controlled
Instrument is treated, is all to apply in terms of physical therapy, can only improve can be irradiated to human body local body, it is difficult to reach deep layer and inside is dirty
Device.Searching fanout free region, effective therapeutic scheme are the research themes of tumor area.Inhibiting effect of the millimeter wave energy to tumour growth
It is the electromagnetic field that is carried by millimeter wave when across tumor tissues, to the charged ion and iron ion action in tumour, example
Such as, intracellular Ca2+ concentration is influenced, DNA restriction endonucleases is activated, makes apoptosis of tumor cells.The millimeter that selected phase is stablized involves conjunction
Suitable frequency parameter, and the complex spectrum assisted therewith and suitable therapeutic effect position are used in combination and can not kill
In the case of hindering normal cell, inhibits the growth of cancer cell or promote its apoptosis.
Invention content
It is an object of the invention to overcome the deficiencies of the prior art and provide a kind of millimeter wave complex treatments of phase stabilization
Instrument.
The present invention is achieved by the following technical solutions：A kind of millimeter wave synthetic therapeutic apparatus of phase stabilization, feature
Be, including the millimeter wave generator of phase compensation and coat its shell, the millimeter wave is to pass through millimeter waveguide
Pipe is drawn, and waveguide nozzle alignment tumor cell tissue position or the acupuncture point of corresponding organ is allowed to be oriented irradiation, the waveguide
It is arc or semicircular smooth tube structure for intraluminal end face blind end can be placed in, also coordinates on the waveguide and be equipped with
Infra-red radiation disk and bass transmitter.
One of preferred embodiment as the present invention, further includes quasi-optical lens, mounting hole, the quasi-optical lens pass through mounting hole
It is mutually fixed with infra-red radiation disk.
One of preferred embodiment as the present invention, the quasi-optical lens are placed in infra-red radiation disk inner ring.
One of preferred embodiment as the present invention, the isolator are ferrite isolator.
One of preferred embodiment as the present invention, further includes phase compensation controller, the phase compensation controller and milli
Metric wave generator is connected.
One of preferred embodiment as the present invention, the phase compensation controller includes microwave-optical signal conversion module, light
Up-conversion and phase compensation block, phase detecting module and broadband optical receiver module, wherein microwave-optical signal modulus of conversion
Block is used to generate the optical frequency comb that frequency interval is microwave signal frequency, and the optical frequency comb passes through light up-conversion and phase compensation
Module filters out two light frequency components, and the two light frequencies component is measured suffered optical fiber link through phase detecting module and disturbed,
And feedback control light up-conversion and phase compensation block, the two light frequency components pass through the broadband light after phase compensation
Receiver module, the millimeter-wave signal that two optical signal beat frequencies are obtained to phase stabilization are exported through millimeter wave generator.
As one of the preferred embodiment of the present invention, the microwave-optical signal conversion module is mainly by a laser, one
Frequency comb generator, a driver and a 25GHz benchmark microwave sources composition, output and the frequency comb generator of laser
Light input port is connected, and 25GHz benchmark microwave sources export the microwave input port after driver amplifies with frequency comb generator
Be connected, adjust the DC offset voltage of frequency comb generator, its output spectrum is made to reach most wide, each frequency component of frequency comb it
Difference is equal to the frequency of 25GHz benchmark microwave signals.
One of preferred embodiment as the present invention, light up-conversion and phase compensation block are mainly coupled by a polarization maintaining optical fibre
Device, a 10MHz rubidium clocks source, a 35MHz signal source, two acousto-optic frequency deviators, a 40MHz voltage controlled oscillator, two
A tunable, two fiber coupler compositions, the output of frequency comb generator are divided into through polarization-maintaining fiber coupler
Two parts, a part are used as reference light, another part through the first acousto-optic frequency deviator up-conversion 35MHz, this 35MHz signal by
Phaselocked loop generation is simultaneously synchronous with 10MHz rubidium clocks source, and two tunables filter out two frequency components of light comb respectively,
A wherein higher frequency component again after rising tone optical frequency offset device up-conversion 40MHz with another frequency component through first
Fiber coupler couples, and two lightwave signals being coupled together are divided into two parts, a part of optical signal after the second fiber coupler
Interfere with baseline optical signal, phase perturbation signal is measured in phase detector module, another part turns through broadband optical receiver
Turn to millimeter-wave signal, the output light frequency of the output control rising tone optical frequency offset device of 40MHz voltage controlled oscillators.
As one of the preferred embodiment of the present invention, the phase detecting module is mainly by a narrowband photoreceiver, one
Power splitter, three centre frequencies are respectively the bandpass filter of 35MHz, 75MHz and 40MHz, a frequency mixer, a low frequency mirror
Phase device, a loop filter composition, a part of optical signal with baseline optical signal interference are obtained through narrowband photoreceiver
The two Frequency components of 35MHz and 75MHz, the output of narrowband photoreceiver are connected with power splitter, 35MHz and 75MHz band logicals
Filter is connected with power splitter respectively filters out the two frequency components, the two frequency components are mixed through frequency mixer, frequency mixer
Output is connected with 40MHz bandpass filters filters out 40MHz frequency components, the 40MHz frequency component signals and 10MHz rubidium clocks source letter
Number it is connected with low frequency phase discriminator, the phase error signal of low frequency phase discriminator output exports control after loop filter integrates
40MHz voltage controlled oscillators, 40MHz voltage controlled oscillators control the output light phase of acousto-optic frequency deviator.
The present invention compared with prior art the advantages of be：The present invention is drawn by millimeter waveguide pipe, allows waveguide nozzle pair
Prospective tumor cell tissue position or the acupuncture point of corresponding organ are oriented irradiation, are wrapped up in around human body around a millimeter wave reflection
Band makes a millimeter wave energy focus in tumor cell tissue, charged ion and iron particle in tumor tissues is interfered, to inhibit
The growth of tumour, the frequency and intensity for the millimeter wave that selected phase is stablized, so that it may in the case where not killing normal cell,
Inhibit the growth of tumour cell or promotes its apoptosis.
Description of the drawings
Fig. 1 is the structural schematic diagram of the present invention；
Fig. 2 is the phase compensation controller principle schematic of the present invention.
Specific implementation mode
It elaborates below to the embodiment of the present invention, the present embodiment is carried out lower based on the technical solution of the present invention
Implement, gives detailed embodiment and specific operating process, but protection scope of the present invention is not limited to following implementation
Example.
Such as Fig. 1：A kind of millimeter wave synthetic therapeutic apparatus of phase stabilization, including the millimeter wave generator of a phase compensation with
And coat its shell 1, the millimeter wave is drawn by millimeter waveguide pipe 2, allow portions of 2 mouthfuls of waveguide alignment tumor cell tissue
Position or the acupuncture point of corresponding organ are oriented irradiation, the waveguide 2 for can be placed in intraluminal end face blind end be arc or
Semicircular smooth tube structure, also cooperation (is not marked equipped with infra-red radiation disk 3 with bass transmitter in figure on the waveguide 2
Show).
One of preferred embodiment as the present invention, further includes quasi-optical lens 5, mounting hole 4, the quasi-optical lens 5 pass through peace
Dress hole 4 is fixed with 3 phase of infra-red radiation disk.
One of preferred embodiment as the present invention, the quasi-optical lens 5 are placed in 3 inner ring of infra-red radiation disk.
One of preferred embodiment as the present invention, the isolator are ferrite isolator.
One of preferred embodiment as the present invention, further includes phase compensation controller, the phase compensation controller and milli
Metric wave generator is connected.
Such as Fig. 2, the phase compensation controller includes microwave-optical signal conversion module, light up-conversion and phase compensation mould
Block, phase detecting module and broadband optical receiver module, wherein microwave-optical signal conversion module is for generating frequency interval
For the optical frequency comb of microwave signal frequency, the optical frequency comb filters out two light frequencies point by light up-conversion and phase compensation block
Amount, the two light frequencies component is measured suffered optical fiber link through phase detecting module and is disturbed, and feedback control light up-conversion
And phase compensation block, the two light frequency components after phase compensation by the broadband optical receiver module, by two light
The millimeter-wave signal that signal beat frequency obtains phase stabilization is exported through millimeter wave generator.
As one of the preferred embodiment of the present invention, the microwave-optical signal conversion module is mainly by a laser, one
Frequency comb generator, a driver and a 25GHz benchmark microwave sources composition, output and the frequency comb generator of laser
Light input port is connected, and 25GHz benchmark microwave sources export the microwave input port after driver amplifies with frequency comb generator
Be connected, adjust the DC offset voltage of frequency comb generator, its output spectrum is made to reach most wide, each frequency component of frequency comb it
Difference is equal to the frequency of 25GHz benchmark microwave signals.
One of preferred embodiment as the present invention, light up-conversion and phase compensation block are mainly coupled by a polarization maintaining optical fibre
Device, a 10MHz rubidium clocks source, a 35MHz signal source, two acousto-optic frequency deviators, a 40MHz voltage controlled oscillator, two
A tunable, two fiber coupler compositions, the output of frequency comb generator are divided into through polarization-maintaining fiber coupler
Two parts, a part are used as reference light, another part through the first acousto-optic frequency deviator up-conversion 35MHz, this 35MHz signal by
Phaselocked loop generation is simultaneously synchronous with 10MHz rubidium clocks source, and two tunables filter out two frequency components of light comb respectively,
A wherein higher frequency component again after rising tone optical frequency offset device up-conversion 40MHz with another frequency component through first
Fiber coupler couples, and two lightwave signals being coupled together are divided into two parts, a part of optical signal after the second fiber coupler
Interfere with baseline optical signal, phase perturbation signal is measured in phase detector module, another part turns through broadband optical receiver
Turn to millimeter-wave signal, the output light frequency of the output control rising tone optical frequency offset device of 40MHz voltage controlled oscillators.
As one of the preferred embodiment of the present invention, the phase detecting module is mainly by a narrowband photoreceiver, one
Power splitter, three centre frequencies are respectively the bandpass filter of 35MHz, 75MHz and 40MHz, a frequency mixer, a low frequency mirror
Phase device, a loop filter composition, a part of optical signal with baseline optical signal interference are obtained through narrowband photoreceiver
The two Frequency components of 35MHz and 75MHz, the output of narrowband photoreceiver are connected with power splitter, 35MHz and 75MHz band logicals
Filter is connected with power splitter respectively filters out the two frequency components, the two frequency components are mixed through frequency mixer, frequency mixer
Output is connected with 40MHz bandpass filters filters out 40MHz frequency components, the 40MHz frequency component signals and 10MHz rubidium clocks source letter
Number it is connected with low frequency phase discriminator, the phase error signal of low frequency phase discriminator output exports control after loop filter integrates
40MHz voltage controlled oscillators, 40MHz voltage controlled oscillators control the output light phase of acousto-optic frequency deviator.
The present invention is drawn by millimeter waveguide pipe, is allowed waveguide nozzle to be directed at tumor cell tissue position or is corresponded to organ
Acupuncture point is oriented irradiation, is wrapped up in around human body around a millimeter wave reflection band, a millimeter wave energy is made to focus on tumour cell
Tissue interferes charged ion and iron particle in tumor tissues, to inhibit the growth of tumour, the milli that selected phase is stablized
The frequency and intensity of metric wave, so that it may in the case where not killing normal cell, to inhibit the growth of tumour cell or it is promoted to wither
It dies.
The present invention program to the processing of optical signal by reaching millimeter-wave signal phase compensation purpose and the phase of optical signal
It is controlled by voltage controlled oscillator, the phase compensation range of voltage controlled oscillator is unrestricted, thus overcomes microwave delay line and optical fiber prolongs
When line the limitation that is limited in scope of phase compensation.
The foregoing is merely illustrative of the preferred embodiments of the present invention, is not intended to limit the invention, all essences in the present invention
All any modification, equivalent and improvement etc., should all be included in the protection scope of the present invention made by within refreshing and principle.
Claims (9)
1. a kind of millimeter wave synthetic therapeutic apparatus of phase stabilization, which is characterized in that the millimeter wave including a phase compensation occurs
Device and coat its shell, the millimeter wave is drawn by millimeter waveguide pipe, allow waveguide nozzle be aligned tumor cell tissue
Position or the acupuncture point of corresponding organ are oriented irradiation, the waveguide for can be placed in intraluminal end face blind end be arc or
Semicircular smooth tube structure, also cooperation is equipped with infra-red radiation disk and bass transmitter on the waveguide.
2. the millimeter wave synthetic therapeutic apparatus of phase stabilization according to claim 1, which is characterized in that further include quasi-optical
Mirror, mounting hole, the quasi-optical lens are mutually fixed by mounting hole and infra-red radiation disk.
3. the millimeter wave synthetic therapeutic apparatus of phase stabilization according to claim 1, which is characterized in that the quasi-optical lens are set
In infra-red radiation disk inner ring.
4. the millimeter wave synthetic therapeutic apparatus of phase stabilization according to claim 1, which is characterized in that the isolator is iron
Oxysome isolator.
5. the millimeter wave synthetic therapeutic apparatus of phase stabilization according to claim 1, which is characterized in that further include phase compensation
Controller, the phase compensation controller are connected with millimeter wave generator.
6. the millimeter wave synthetic therapeutic apparatus of phase stabilization according to claim 5, which is characterized in that the phase compensation control
Device processed includes microwave-optical signal conversion module, light up-conversion and phase compensation block, phase detecting module and broadband light-receiving
Machine module, wherein microwave-optical signal conversion module is used to generate the optical frequency comb that frequency interval is microwave signal frequency, described
Optical frequency comb filters out two light frequency components by light up-conversion and phase compensation block, and the two light frequencies component is through phase-detection
Module measures suffered optical fiber link disturbance, and feedback control light up-conversion and phase compensation block, two light frequencies
Component by the broadband optical receiver module after phase compensation, believe by the millimeter wave that two optical signal beat frequencies are obtained to phase stabilization
It number is exported through millimeter wave generator.
7. the millimeter wave synthetic therapeutic apparatus of phase stabilization according to claim 6, which is characterized in that the microwave-light letter
Number conversion module is mainly by a laser, a frequency comb generator, a driver and a 25GHz benchmark microwave source group
At the output of laser is connected with the light input port of frequency comb generator, and the output of 25GHz benchmark microwave sources is amplified through driver
It is connected afterwards with the microwave input port of frequency comb generator, adjusts the DC offset voltage of frequency comb generator, make its output light
Spectrum reaches most wide, and the difference of each frequency component of frequency comb is equal to the frequency of 25GHz benchmark microwave signals.
8. the millimeter wave synthetic therapeutic apparatus of phase stabilization according to claim 6, which is characterized in that light up-conversion and phase
Compensating module is mainly by a polarization-maintaining fiber coupler, a 10MHz rubidium clocks source, a 35MHz signal source, two acousto-optic frequencies
Deviator, a 40MHz voltage controlled oscillator, two tunables, two fiber coupler compositions, frequency comb occur
The output of device is divided into two parts through polarization-maintaining fiber coupler, and a part is used as reference light, another part inclined through the first acousto-optic frequency
Device up-conversion 35MHz is moved, this 35MHz signal is generated by phaselocked loop and, two tunable optical bandpass filterings synchronous with 10MHz rubidium clocks source
Device filters out two frequency components of light comb respectively, wherein a higher frequency component on rising tone optical frequency offset device again through becoming
It is coupled through the first fiber coupler with another frequency component after frequency 40MHz, two lightwave signals being coupled together are through the second optical fiber coupling
It is divided into two parts after clutch, a part of optical signal is interfered with baseline optical signal, and phase perturbation is measured in phase detector module
Signal, another part are converted into millimeter-wave signal through broadband optical receiver, and the output of 40MHz voltage controlled oscillators controls the second acousto-optic
The output light frequency of frequency deviator.
9. the millimeter wave synthetic therapeutic apparatus of phase stabilization according to claim 6, which is characterized in that the phase-detection mould
Block is mainly by a narrowband photoreceiver, and a power splitter, three centre frequencies are respectively the band of 35MHz, 75MHz and 40MHz
Bandpass filter, a frequency mixer, a low frequency phase discriminator, a loop filter composition, one with baseline optical signal interference
Spectroscopic signal obtains the two Frequency components of 35MHz and 75MHz through narrowband photoreceiver, the output of narrowband photoreceiver with
Power splitter is connected, 35MHz and 75MHz bandpass filters are connected with power splitter respectively filters out the two frequency components, the two frequencies
Rate component is mixed through frequency mixer, and the output of frequency mixer is connected with 40MHz bandpass filters filters out 40MHz frequency components, the 40MHz
Frequency component signal and 10MHz rubidium clocks source signal are connected with low frequency phase discriminator, the phase error signal warp of low frequency phase discriminator output
Output control 40MHz voltage controlled oscillators, 40MHz voltage controlled oscillators control the defeated of acousto-optic frequency deviator after loop filter integral
Go out light phase.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201810074208.6A CN108578901A (en) | 2018-01-25 | 2018-01-25 | A kind of millimeter wave synthetic therapeutic apparatus of phase stabilization |
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| CN201810074208.6A CN108578901A (en) | 2018-01-25 | 2018-01-25 | A kind of millimeter wave synthetic therapeutic apparatus of phase stabilization |
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Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1196963A (en) * | 1997-04-21 | 1998-10-28 | 西安电子科技大学 | MM wave therapeutic instrument |
| CN1277879A (en) * | 2000-07-14 | 2000-12-27 | 北京东方康威科技发展中心 | Millimetre wave therapeutical apparatus |
| CN102974042A (en) * | 2011-09-02 | 2013-03-20 | 王守国 | Pulsed millimeter-wave tumor treatment instrument |
| CN103684611A (en) * | 2013-12-04 | 2014-03-26 | 上海交通大学 | Phase stabilized millimeter wave generating system and method |
-
2018
- 2018-01-25 CN CN201810074208.6A patent/CN108578901A/en active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1196963A (en) * | 1997-04-21 | 1998-10-28 | 西安电子科技大学 | MM wave therapeutic instrument |
| CN1277879A (en) * | 2000-07-14 | 2000-12-27 | 北京东方康威科技发展中心 | Millimetre wave therapeutical apparatus |
| CN102974042A (en) * | 2011-09-02 | 2013-03-20 | 王守国 | Pulsed millimeter-wave tumor treatment instrument |
| CN103684611A (en) * | 2013-12-04 | 2014-03-26 | 上海交通大学 | Phase stabilized millimeter wave generating system and method |
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Application publication date: 20180928 |