CN108578753A - A kind of disinfectant dressing and preparation method thereof - Google Patents
A kind of disinfectant dressing and preparation method thereof Download PDFInfo
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- CN108578753A CN108578753A CN201810205017.9A CN201810205017A CN108578753A CN 108578753 A CN108578753 A CN 108578753A CN 201810205017 A CN201810205017 A CN 201810205017A CN 108578753 A CN108578753 A CN 108578753A
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- disinfectant
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/42—Use of materials characterised by their function or physical properties
- A61L15/46—Deodorants or malodour counteractants, e.g. to inhibit the formation of ammonia or bacteria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/18—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing inorganic materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/20—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing organic materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/22—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
- A61L15/26—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/42—Use of materials characterised by their function or physical properties
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/10—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing inorganic materials
- A61L2300/102—Metals or metal compounds, e.g. salts such as bicarbonates, carbonates, oxides, zeolites, silicates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/10—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing inorganic materials
- A61L2300/102—Metals or metal compounds, e.g. salts such as bicarbonates, carbonates, oxides, zeolites, silicates
- A61L2300/104—Silver, e.g. silver sulfadiazine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/404—Biocides, antimicrobial agents, antiseptic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/45—Mixtures of two or more drugs, e.g. synergistic mixtures
Abstract
The invention discloses a kind of disinfectant dressing, including base fabric and dressing liquid, the dressing liquid is made of following components：Silver sulfate, zinc salt and persulfuric acid (hydrogen) salt；The zinc salt is one or more kinds of in zinc sulfate, zinc lactate, zinc gluconate and zinc citrate；The pH of the dressing liquid is 47；The base fabric is hydrophobic base fabric.The disinfectant dressing has preferable stability and preferable gas permeability, can promote wound healing.
Description
Technical field
The present invention relates to a kind of medical devices more particularly to a kind of disinfectant dressing and preparation method thereof.
Background technology
Wound can faster heal in wet environment, but wet environment is also easy to grow bacterium, causes wound infection
Slow down healing process.It can inhibit the growth of bacterium using antibiotic, but the drug resistance of bacterium can be caused to cause suprainfection.
Silver compound has the antibacterial effect of wide spectrum, and is not easy to cause the drug resistance of bacterium.Dressing base fabric includes gauze, non-woven fabrics etc.
The wet environment that can maintain wound, painting carrying silver ion can reach fungistatic effect on gauze, reduce the risk of wound infection.
Zinc plays the role of promoting lymphopoiesis and mobility, and to maintaining, epithelium and mucosal tissue are normal, defence is thin
Bacterium, Virus entry promote the cutaneous lesions such as wound healing, reduction acne to play an important role.
Traditional gauze is made of materials such as cotton, fiber crops, and this kind of gauze can protect wound to be not directly contacted with external environment, subtract
Few chance by environmental stimuli and infection promotes wound healing.This kind of gauze is simple for process, cheap, easy to make.But
The wet environment of wound can not effectively be maintained by being this kind of gauze, and easily be adhered wound, cause the mechanical damage in dressing.This hair
It is bright that a kind of gauze having added dimeticone is provided, wound and gauze adhesion can be prevented, avoids causing secondary damage when more change dressings
Wound.Chinese patent Publication No. 202136483U application numbers disclosed in 8 days 2 months 08 day February in 2012 of Chinese patent in 2012
For a kind of entitled medical application of patent of invention of 201120208013.X, including base material and not doing positioned at base material inner surface
Glue-line, wherein non-drying glue layer is bonded with dressing layer, it is characterised in that：The dressing layer includes outer layer non-woven fabrics and setting
In the water absorption pad in non-woven fabrics.This medical application pliability is high, easy to use, good permeability, good water absorption, adhesion wound
Mouthful, patient comfort binds up a wound tight, and therapeutic effect is good.But it is complicated, is easy to fall off, and moistening effect is not
It is good.
Invention content
For overcome the deficiencies in the prior art, one of the objects of the present invention is to provide it is a kind of can effectively moisturizing, ventilative, anti-
The only medical disinfectant dressing of adhesion.
The second object of the present invention is to provide the preparation method of this kind of disinfectant dressing.
An object of the present invention adopts the following technical scheme that realization：
A kind of disinfectant dressing, including base fabric and dressing liquid, the dressing liquid are made of following components：Silver sulfate, zinc salt and
Persulfuric acid (hydrogen) salt；The zinc salt is one or more kinds of in zinc sulfate, zinc lactate, zinc gluconate and zinc citrate；It applies
The pH of feed liquid is 4-7；The base fabric is hydrophobic base fabric.
Persulfuric acid (hydrogen) salt refers to persulfate or persulfuric acid hydrogen salt.
Further, persulfuric acid (hydrogen) salt is in potassium peroxydisulfate, sodium peroxydisulfate, potassium hydrogen persulfate and hydrogen persulfate sodium
One or more.
Further, the dressing liquid further includes pH adjusting agent, and the pH adjusting agent is sulfuric acid or niter cake or sulphur
Potassium hydrogen phthalate.
Further, the base fabric is a kind of in the woven fabric for being coated with dimethicone, non-woven fabrics or gauze.
Further, the every 100 millimeters of warp-wise yarn line numbers of the base fabric are 90 ± 30；Every 100 millimeters of broad-wise yarn line numbers are 70
±25。
Further, in dressing liquid, a concentration of 1-6wt ‰ of zinc salt；The concentration of persulfuric acid (hydrogen) salt is less than
0.1wt ‰, concentration of silver ions are 1-5wt ‰.
The second object of the present invention adopts the following technical scheme that realization：
A kind of method of above-mentioned disinfectant dressing, includes the following steps：
1) dressing liquid is prepared：Silver sulfate, zinc salt and persulfuric acid (hydrogen) salt are diluted with water uniformly mixed, obtain dressing liquid；
2) it is coated with：Dressing liquid is coated in base fabric, it is dry；
3) oiling：Dimethicone is coated in dry base fabric, it is hermetically sealed；
4) it irradiates：Irradiation 10-40 minutes is carried out using the irradiation intensity of 10-50kGy, obtains disinfectant dressing.
Further, in step 1), pH to 5-6 is adjusted.
Further, in step 2), the dry means used for heated-air drying, be dried under reduced pressure or infra-red drying, dry
Temperature is less than 150 DEG C.
Further, in step 3), the addition of dimethicone is per 0.6-1g/100cm2Base fabric.
Compared with prior art, the beneficial effects of the present invention are：
Disinfectant dressing provided by the invention, base fabric are hydrophobicity base fabric, have good gas permeability；PH is suitable in dressing liquid
In, contain silver ion and zinc ion, sterilized in such a way that silver-colored zinc ion is combined, pass through the infiltrating of physics, chemistry
The modes such as coupling promote wound healing；It is coated with dimeticone in base fabric, the microenvironment of a moistening, moisturizing effect can be maintained
Fruit is good, meets the wound repair theory of " wet union ", while wound granulation can be prevented to be adhered base fabric；
The medical application of the present invention is simple in structure, easy to use, soft flexible, easy curling, to the compliance of wound compared with
It is good, it has good value for applications.
Specific implementation mode
In the following, in conjunction with specific implementation mode, the present invention is described further, it should be noted that is do not collided
Under the premise of, new embodiment can be formed between various embodiments described below or between each technical characteristic in any combination.
In detailed description below, such as non-specified otherwise, recorded raw material or material can pass through commercially available means
It obtains.
Embodiment 1：
A kind of disinfectant dressing, including base fabric and dressing liquid, the dressing liquid are made of the following components of following weight：
The niter cake of 1.517g silver sulfates, 1.517g zinc sulfate and 0.08g potassium hydrogen persulfates and regulated quantity；The base fabric is hydrophobic group
Cloth.
The preparation method of the disinfectant dressing, includes the following steps：
1) dressing liquid is prepared：Add 300g water to dilute silver sulfate, zinc sulfate, potassium hydrogen persulfate, is stirred at a temperature of 25 DEG C
15h adds the aqueous solution of niter cake to adjust pH to 5-5.5, obtains dressing liquid；
2) it is coated with：12.1g dressing liquid will be drawn to be coated on the large-mesh looped fabric of 14.3cm × 12.7cm, be suspended on baking
It is dried in case, preliminary drying 10 minutes first in 135 DEG C of baking ovens, then returns again in 168 DEG C of baking ovens and dry 10 minutes；The color of dressing
For brown；
3) oiling：1.3g dimethicones are coated in dry base fabric, it is hermetically sealed；
4) it irradiates：Irradiation 25min is carried out using the irradiation intensity of 30kGy, obtains disinfectant dressing.
Embodiment 2：
A kind of disinfectant dressing, including base fabric and dressing liquid, the dressing liquid are made of the following components of following weight：
The potassium acid sulfate of 1.517g silver sulfates, 1.517g zinc sulfate, 0.08g potassium hydrogen persulfates and regulated quantity；The base fabric is hydrophobic group
Cloth.
The preparation method of the disinfectant dressing, includes the following steps：
1) dressing liquid is prepared：Add 300g water to dilute silver sulfate, zinc sulfate, potassium hydrogen persulfate, is stirred at a temperature of 25 DEG C
15h adds the aqueous solution of potassium acid sulfate to adjust pH to 5.0-5.5, obtains dressing liquid；
2) it is coated with：12.1g dressing liquid will be drawn to be coated on the large-mesh looped fabric of 14.3cm × 12.7cm, be suspended on baking
It is dried in case, preliminary drying 10 minutes first in 110 DEG C of baking ovens, then returns again in 130 DEG C of baking ovens and dry 10 minutes；The color of dressing
It is faint yellow；
3) oiling：1.2g dimethicones are coated in dry base fabric, it is hermetically sealed；
4) it irradiates：Irradiation 25 minutes is carried out using the irradiation intensity of 25kGy, obtains disinfectant dressing.
Embodiment 3：
A kind of disinfectant dressing, including base fabric and dressing liquid, the dressing liquid are made of the following components of following weight：
The potassium acid sulfate of 1.517g silver sulfates, 4.282g zinc gluconates, 0.08g potassium hydrogen persulfates and regulated quantity；The base fabric is thin
Water base cloth.
The preparation method of the disinfectant dressing, includes the following steps：
1) dressing liquid is prepared：300g water is added to dilute silver sulfate, zinc gluconate, potassium hydrogen persulfate, at a temperature of 25 DEG C
15h is stirred, adds the aqueous solution of potassium acid sulfate to adjust pH to 5.0-5.5, obtains dressing liquid；
2) it is coated with：12.5g dressing liquid will be drawn to be coated on the large-mesh looped fabric of 14.3cm × 12.7cm, be suspended on baking
It is dried in case, preliminary drying 15 minutes first in 130 DEG C of baking ovens, then returns again in 168 DEG C of baking ovens and dry 10 minutes；The color of dressing
For brown；
3) oiling：1.5g dimethicones are coated in dry base fabric, it is hermetically sealed；
4) it irradiates：Irradiation 25 minutes is carried out using the irradiation intensity of 30kGy, obtains disinfectant dressing.
Embodiment 4：
A kind of disinfectant dressing, including base fabric and dressing liquid, the dressing liquid are made of the following components of following weight：
The potassium acid sulfate of 1.517g silver sulfates, 2.288g zinc lactates, 0.08g potassium hydrogen persulfates and regulated quantity；The base fabric is hydrophobic group
Cloth.
The preparation method of the disinfectant dressing, includes the following steps：
1) dressing liquid is prepared：Add 300g water to dilute silver sulfate, zinc lactate, potassium hydrogen persulfate, is stirred at a temperature of 25 DEG C
15h adds dilute sulfuric acid to adjust pH to 5.5-6.0, obtains dressing liquid；
2) it is coated with：12.3g dressing liquid will be drawn to be coated on the large-mesh looped fabric of 14.3cm × 12.7cm, be suspended on baking
It is dried in case, preliminary drying 15 minutes first in 110 DEG C of baking ovens, then returns again in 130 DEG C of baking ovens and dry 10 minutes；The color of dressing
For brown color；
3) oiling：1.8g dimethicones are coated in dry base fabric, it is hermetically sealed；
4) it irradiates：Irradiation 25 minutes is carried out using the irradiation intensity of 20kGy, obtains disinfectant dressing.
Embodiment 5：
A kind of disinfectant dressing, including base fabric and dressing liquid, the dressing liquid are made of the following components of following weight：
The potassium acid sulfate of 1.517g silver sulfates, 1.955g zinc citrates, 0.08g potassium hydrogen persulfates and regulated quantity；The base fabric is hydrophobic
Base fabric.
The preparation method of the disinfectant dressing, includes the following steps：
1) dressing liquid is prepared：Add 300g water to dilute silver sulfate, zinc citrate, potassium hydrogen persulfate, is stirred at a temperature of 25 DEG C
15h is mixed, adds dilute sulfuric acid to adjust pH to 5.5-6.0, obtains dressing liquid；
2) it is coated with：12.3g dressing liquid will be drawn to be coated on the large-mesh looped fabric of 14.3cm × 12.7cm, by infrared
Lamp dry 15min at 120 DEG C；The color of dressing is faint yellow；
3) oiling：1.6g dimethicones are coated in dry base fabric, it is hermetically sealed；
4) it irradiates：Irradiation 25 minutes is carried out using the irradiation intensity of 20kGy, obtains disinfectant dressing.
Embodiment 6：
A kind of disinfectant dressing, including base fabric and dressing liquid, the dressing liquid are made of the following components of following weight：
The niter cake of 1.517g silver sulfates, 1.955g zinc citrates, 0.08g potassium hydrogen persulfates and regulated quantity；The base fabric is hydrophobic
Base fabric.
The preparation method of the disinfectant dressing, includes the following steps：
1) dressing liquid is prepared：300g water is added to dilute in silver sulfate, zinc citrate, hydrogen persulfate sodium potassium, at a temperature of 25 DEG C
15h is stirred, adds dilute sulfuric acid to adjust pH to 5.5-6.0, obtains dressing liquid；
2) it is coated with：12.3g dressing liquid will be drawn to be coated on the large-mesh looped fabric of 14.3cm × 12.7cm, it is true in 80 DEG C
The dry 30min of sky；The color of dressing is faint yellow；
3) oiling：1.7g dimethicones are coated in dry base fabric, it is hermetically sealed；
4) it irradiates：Irradiation 25 minutes is carried out using the irradiation intensity of 20kGy, obtains disinfectant dressing.
Performance detection and effect assessment
1. bactericidal property detects
The disinfectant dressing that embodiment 1-6 is obtained carries out antibacterial tests, and concrete operations are as follows：
By coupons group：The sample for the disinfectant dressing that embodiment 1-6 is obtained is cut into the round print of a diameter of 5cm,
It is placed in triangular flask bottom, then by a concentration of 105-106Bacterium solution take 0.5mL homogeneous immersion circle prints.
By the 100mL bacterium solution dilutions of addition immediately of " 0 " time of contact group, 2min is shaken, draws 0.5mL in dilution bottle,
It is diluted to 10 with ten times of gradient dilution methods2-103；
" for 24 hours " the needs culture organized adds 100mL dilutions afterwards for 24 hours, shakes 2min, draws 0.5mL in dilution bottle, uses
Ten times of gradient dilution methods are diluted to 103-104.1mL is drawn, is placed in plate, each dilution does two Duplicate Samples, then with cool
It is down flat plate to 40-45 DEG C of nutrient agar, 48h is cultivated in 30-35 DEG C of incubator.
Reference substance group：Control print is cut into the round print of a diameter of 5cm, is placed in triangular flask bottom, then will be a concentration of
The bacterium solution of 105-106 takes 0.5mL homogeneous immersion circle prints.Subsequent operation is same as above.
Sample group：The obtained sample of the present invention is cut into the round print of a diameter of 5cm, is placed in triangular flask bottom, is stood
100mL dilutions are added, shake 2min, draws 1mL, is placed in plate, does two Duplicate Samples, then with cool to 40-45 DEG C
Nutrient agar is down flat plate, and 48h is cultivated in 30-35 DEG C of incubator.
Bacteriostasis rate is calculated by following equation：
B：" 0 " time of contact test sample；
B’:" 0 " time of contact compares print viable count
A：" for 24 hours " by coupons viable count；
A’:" for 24 hours " print viable count is compareed；
It is as follows to the inhibiting rate of Escherichia coli (E.coli) and staphylococcus aureus (E.coli)：
The results show that disinfectant dressing provided by the invention to common colibacillus, staphylococcus aureus all have compared with
Good antibacterial effect.
Dressing of the present invention, a total of four layers, layer structure and mesh are conducive to water suction drainage and moisturizing, and dressing material is pure
The big eye looped fabric of cotton either non-woven fabrics or textile cloth, dressing are loaded with antibacterial silver ion and zinc compound, the antimicrobial silver from
Son and the infiltration of zinc compound physics are on the dressing layer.Dimeticone can be also coated in dressing.
The base fabric of Medical sterilization dressing of the present invention can preferably by compound by layer structure cloth and mesh cloth and
At being impregnated with dressing liquid in base fabric, dimeticone be coated in base fabric.
The silver sulfate that the disinfectant dressing is combined with physics pattern of invasion, base fabric have water imbibition appropriate and good ventilative
Property, it can be by physically or chemically acting on coupling silver sulfate sterilization, while zinc salt can promote wound healing.Silver sulfate is in aqueous solution
Solubility is low, can slowly release silver ion in the micro- wet environment in wound, play lasting antibacterial effect.In every 300cm2
2-3 grams of dimeticone is added dropwise on gauze, gauze adhesion granulation tissue can be prevented.
The above embodiment is only the preferred embodiment of the present invention, and the scope of protection of the present invention is not limited thereto,
The variation and replacement for any unsubstantiality that those skilled in the art is done on the basis of the present invention belong to institute of the present invention
Claimed range.
Claims (10)
1. a kind of disinfectant dressing, including base fabric and dressing liquid, which is characterized in that the dressing liquid is made of following components：Sulfuric acid
Silver, zinc salt and persulfuric acid (hydrogen) salt；The zinc salt is one kind or two in zinc sulfate, zinc lactate, zinc gluconate and zinc citrate
Kind or more；The pH of the dressing liquid is 4-7；The base fabric is hydrophobic base fabric.
2. disinfectant dressing as described in claim 1, which is characterized in that persulfuric acid (hydrogen) salt is potassium peroxydisulfate, persulfuric acid
One or more of sodium, potassium hydrogen persulfate and hydrogen persulfate sodium.
3. disinfectant dressing as described in claim 1, which is characterized in that the dressing liquid further includes pH adjusting agent, the pH tune
It is sulfuric acid or niter cake or potassium acid sulfate to save agent.
4. disinfectant dressing as described in claim 1, which is characterized in that the base fabric be the woven fabric for being coated with dimethicone,
It is a kind of in non-woven fabrics or gauze.
5. disinfectant dressing as claimed in claim 4, which is characterized in that the every 100 millimeters of warp-wise yarn line numbers of base fabric be 90 ±
30；Every 100 millimeters of broad-wise yarn line numbers are 70 ± 25.
6. disinfectant dressing as described in claim 1, which is characterized in that in dressing liquid, a concentration of 1-6wt ‰ of zinc salt；It is described
The concentration of persulfuric acid (hydrogen) salt is less than 0.1wt ‰, and concentration of silver ions is 1-5wt ‰.
7. a method of disinfectant dressing as claimed in any one of claims 1 to 6 is prepared, is included the following steps：
1) dressing liquid is prepared：Silver sulfate, zinc salt and persulfuric acid (hydrogen) salt are diluted with water uniformly mixed, obtain dressing liquid；
2) it is coated with：Dressing liquid is coated in base fabric, it is dry；
3) oiling：Dimethicone is coated in dry base fabric, it is hermetically sealed；
4) it irradiates：Irradiation 10-40 minutes is carried out using the irradiation intensity of 10-50kGy, obtains disinfectant dressing.
8. the method for claim 7, which is characterized in that in step 1), adjust pH to 5-6.
9. the method for claim 7, which is characterized in that in step 2), the dry means used is heated-air drying, decompressions
Dry or infra-red drying, dry temperature are less than 150 DEG C.
10. the method for claim 7, which is characterized in that in step 3), the addition of dimethicone is per 0.6-
1g/100cm2Base fabric.
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| CN201810205017.9A CN108578753B (en) | 2018-03-13 | 2018-03-13 | Bactericidal dressing and preparation method thereof |
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| CN201810205017.9A CN108578753B (en) | 2018-03-13 | 2018-03-13 | Bactericidal dressing and preparation method thereof |
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| CN108578753B CN108578753B (en) | 2021-06-29 |
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Cited By (4)
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|---|---|---|---|---|
| CN114432485A (en) * | 2022-02-15 | 2022-05-06 | 周建大 | pH-responsive quaternary ammonium salt antibacterial dressing and preparation method thereof |
| CN115957367A (en) * | 2022-12-02 | 2023-04-14 | 浙江兄弟控优生物科技有限公司 | High-biocompatibility coating liquid and hydrophobic antibacterial gauze dressing |
| CN116251223A (en) * | 2023-05-09 | 2023-06-13 | 天津包钢稀土研究院有限责任公司 | Rare earth metal-based dressing for wound surface sterilization and preparation method thereof |
| CN114182522B (en) * | 2020-09-16 | 2023-10-24 | 青岛尼希米生物科技有限公司 | Antibacterial antiviral mildew-proof finishing liquid and application thereof, antibacterial antiviral mildew-proof cellulose fiber and preparation method and application thereof |
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| US20170202877A1 (en) * | 2016-01-19 | 2017-07-20 | Reoxcyn Discoveries Group, Inc. | Hypochlorite formulations for wound healing |
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114182522B (en) * | 2020-09-16 | 2023-10-24 | 青岛尼希米生物科技有限公司 | Antibacterial antiviral mildew-proof finishing liquid and application thereof, antibacterial antiviral mildew-proof cellulose fiber and preparation method and application thereof |
| CN114432485A (en) * | 2022-02-15 | 2022-05-06 | 周建大 | pH-responsive quaternary ammonium salt antibacterial dressing and preparation method thereof |
| CN115957367A (en) * | 2022-12-02 | 2023-04-14 | 浙江兄弟控优生物科技有限公司 | High-biocompatibility coating liquid and hydrophobic antibacterial gauze dressing |
| CN116251223A (en) * | 2023-05-09 | 2023-06-13 | 天津包钢稀土研究院有限责任公司 | Rare earth metal-based dressing for wound surface sterilization and preparation method thereof |
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