CN108576823A - A kind of anti-oxidant, anti-aging symphysis unit composition and its preparation and application - Google Patents

A kind of anti-oxidant, anti-aging symphysis unit composition and its preparation and application Download PDF

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Publication number
CN108576823A
CN108576823A CN201810104943.7A CN201810104943A CN108576823A CN 108576823 A CN108576823 A CN 108576823A CN 201810104943 A CN201810104943 A CN 201810104943A CN 108576823 A CN108576823 A CN 108576823A
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lactobacillus
aging
oxidant
unit composition
symphysis unit
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CN201810104943.7A
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Inventor
刘竞元
陈朝银
杨映宁
刘潇阳
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Yunnan Zhongjing National Construction Investment Co Ltd
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Yunnan Zhongjing National Construction Investment Co Ltd
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Publication of CN108576823A publication Critical patent/CN108576823A/en
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    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/135Bacteria or derivatives thereof, e.g. probiotics
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/20Reducing nutritive value; Dietetic products with reduced nutritive value
    • A23L33/21Addition of substantially indigestible substances, e.g. dietary fibres
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2400/00Lactic or propionic acid bacteria
    • A23V2400/11Lactobacillus
    • A23V2400/113Acidophilus
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2400/00Lactic or propionic acid bacteria
    • A23V2400/11Lactobacillus
    • A23V2400/121Brevis
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2400/00Lactic or propionic acid bacteria
    • A23V2400/11Lactobacillus
    • A23V2400/123Bulgaricus
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2400/00Lactic or propionic acid bacteria
    • A23V2400/11Lactobacillus
    • A23V2400/125Casei
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2400/00Lactic or propionic acid bacteria
    • A23V2400/11Lactobacillus
    • A23V2400/133Curvatus
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2400/00Lactic or propionic acid bacteria
    • A23V2400/11Lactobacillus
    • A23V2400/137Delbrueckii
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2400/00Lactic or propionic acid bacteria
    • A23V2400/11Lactobacillus
    • A23V2400/157Lactis
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2400/00Lactic or propionic acid bacteria
    • A23V2400/11Lactobacillus
    • A23V2400/169Plantarum
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2400/00Lactic or propionic acid bacteria
    • A23V2400/11Lactobacillus
    • A23V2400/181Salivarius
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2400/00Lactic or propionic acid bacteria
    • A23V2400/41Pediococcus
    • A23V2400/413Acidilactici

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  • Life Sciences & Earth Sciences (AREA)
  • Mycology (AREA)
  • Health & Medical Sciences (AREA)
  • Nutrition Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

The invention discloses a kind of anti-oxidant, anti-aging symphysis unit composition and its preparation and application, anti-oxidant, anti-aging the symphysis unit composition includes prebiotics and probiotics, and the weight ratio of the prebiotics and probiotics is 1~10:1~10.The symphysis unit composition of the present invention can both play the physiological bacterial activity of probiotics, and cooperation prebiotics optionally quickly increase the quantity of probiotics again, make that probiotic action speed is fast and effect is lasting, to play the physiological function of probiotics and prebiotics simultaneously.The symphysis unit of the present invention effectively facilitates intestinal health; remove toxin; protect intestinal mucosa; mycoderm barrier is maintained, a large amount of harmful substances such as bacterium and toxin in enteron aisle are confined in enteric cavity, while inhibiting the generation of pathogenic bacteria and toxin; remove toxin; intestinal health is kept, the generation of free radical is reduced, to slow down aging.

Description

A kind of anti-oxidant, anti-aging symphysis unit composition and its preparation and application
Technical field
The invention belongs to microbe additive technical fields, and in particular to a kind of anti-oxidant, anti-aging symphysis unit combination Object and its preparation and application.
Background technology
Symphysis unit is also known as Synbiotics or symbiosis member, is the composite article of probiotics and prebiotics.Probiotics is one kind to place Main beneficial active microorganism.And prebiotics refer to a kind of food ingredients that beneficial bacterium can be promoted to grow or substance, be it is a kind of not Easily by the growth of beneficial bacterium or the active beneficial bacteria product of enhancing beneficial bacterium in human consumption but alternative stimulation enteron aisle.
Now in the art, have the relevant report of symphysis unit, but be formulated mostly unreasonable, be unable to reach preferable work( Effect, What is more, and good promotion improvement result cannot be played to internal beneficial flora.And existing symphysis unit composition Specific aim is not strong, and effect is barely satisfactory.
People are in daily life due to inherent or external, or with advancing age, body interior free yl by Cumulative more, the ability of cell clearance free radical gradually declines, and then causes various damage accumulations, directly causes human senility.Skin Skin is body aging one of organ the most apparent in the process, and with advancing age, thinning of skin, water content can occur for skin The symptoms such as reduction, tissue elasticity attenuating, atrophy, corrugation.And particularly with white collar crowd, due to being frequently necessary to be sitting in computer for a long time Before, cause enteron aisle unhealthy, the toxin of body has no idea normally to exclude, and interior free yl accumulation, excessive free radical is attacked Skin Cell is hit, causes skin aging, face turns yellow, spot and flaw increase.In addition to this, it is also to accelerate people that diet is unhealthy The one of the major reasons of body aging may all add a large amount of man-made additive in existing many foods, and such food is taken the photograph Membership causes body to will produce polyradical, destroys cell.In addition barbecue, barbecue, the edible of maror also exacerbate people The aging of body.
For this purpose, a kind of product that can be solved the above problems of research and development is very important.
Invention content
The first object of the present invention is to provide a kind of anti-oxidant, anti-aging symphysis unit composition, the second object of the present invention It is to provide a kind of preparation of anti-oxidant, anti-aging symphysis unit composition, the third object of the present invention is to provide a kind of anti- It aoxidizes, the application of the symphysis unit composition of anti-aging.
The first object of the present invention is achieved in that anti-oxidant, anti-aging the symphysis unit composition includes benefit The weight ratio of raw member and probiotics, the prebiotics and probiotics is 1~10:1~10.
Preferably, the weight ratio of the prebiotics and probiotics is 3~10:1.
Preferably, the weight ratio of the prebiotics and probiotics is 1:1~7.
Preferably, the prebiotics include the ingredient of following weight percent:Trehalose 6~9%, raffinose 1~ 4%, xylo-oligosaccharide 14~17%, oligoisomaltose 1~4%, oligofructose 6~9%, galactooligosaccharide 0.5~2.5%, Chitosan oligosaccharide 6~9%, soyabean oligosaccharides 5~8%, synanthrin 13~16%, aloe polysaccharide 8~11%, konjac polysaccharide 24~27%.
Preferably, the prebiotics include the ingredient of following weight percent:Trehalose 7~8%, raffinose 2~ 3%, xylo-oligosaccharide 15~16%, oligoisomaltose 2~3%, oligofructose 7~8%, galactooligosaccharide 1~2%, shell are few Sugar 7~8%, soyabean oligosaccharides 6~7%, synanthrin 14~15%, aloe polysaccharide 9~10%, konjac polysaccharide 25~26%.
Preferably, the probiotics includes the ingredient of following weight percent:Lactobacillus acidophilus 0.5~3%, short newborn bar It is bacterium 0.4~1.2%, lactobacillus buchneri 0.4~1.2%, Lactobacillus casei 7~27%, Lactobacillus paracasei 0.5~2.5%, curved Bent lactobacillus 0.4~1.2%, lactobacillus bulgaricus 0.4~1.2%, Lactobacillus delbrueckii 0.4~1.2%, lactobacillus plantarum 14 ~57.9%, Lactobacillus salivarius 0.4~1.2%, bacillus subtilis 0~30%, bacillus licheniformis 0~8%, condensation gemma Bacillus 0~6%, bafillus natto 0~8%, bifidobacterium adolescentis 0.4~1.2%, bifidobacterium bifidum 0.4~1.2%, Enterococcus faecalis 0~1.2%, enterococcus faecium 0~5%, Lactococcus lactis 0~5%, clostridium butyricum 0~2.5%, Pediococcus acidilactici 0 ~2.5%, monascus ruber 0~10%.
Preferably, the probiotics includes the ingredient of following weight percent:Lactobacillus acidophilus 0.5~3%, short newborn bar It is bacterium 0.4~1.2%, lactobacillus buchneri 0.4~1.2%, Lactobacillus casei 7~9%, Lactobacillus paracasei 0.5~2.5%, curved Bent lactobacillus 0.4~1.2%, lactobacillus bulgaricus 0.4~1.2%, Lactobacillus delbrueckii 0.4~1.2%, lactobacillus plantarum 14 ~17%, Lactobacillus salivarius 0.4~1.2%, bacillus subtilis 27~30%, bacillus licheniformis 5~8%, condensation gemma Bacillus 3~6%, bafillus natto 5~8%, bifidobacterium adolescentis 0.4~1.2%, bifidobacterium bifidum 0.4~1.2%, Enterococcus faecalis 0.4~1.2%, enterococcus faecium 2~5%, Lactococcus lactis 2~5%, clostridium butyricum 0.5~2.5%, lactic acid sheet Coccus 0.5~2.5%, monascus ruber 7~10%.
Preferably, the probiotics includes the ingredient of following weight percent:Lactobacillus acidophilus 1~2%, Lactobacillus brevis 0.6~1%, lactobacillus buchneri 0.6~1%, Lactobacillus casei 8~9%, Lactobacillus paracasei 1~2%, lactobacillus curvatus 0.6 ~1%, lactobacillus bulgaricus 0.6~1%, Lactobacillus delbrueckii 0.6~1%, lactobacillus plantarum 15~16%, Lactobacillus salivarius 0.6~1%, bacillus subtilis 28~29%, bacillus licheniformis 6~7%, bacillus coagulans 4~5%, natto gemma Bacillus 6~7%, bifidobacterium adolescentis 0.6~1%, bifidobacterium bifidum 0.6~1%, enterococcus faecalis 0.6~1%, dung intestines ball Bacterium 3~4%, Lactococcus lactis 3~4%, clostridium butyricum 1~2%, Pediococcus acidilactici 1~2%, monascus ruber 8~9%.
The second object of the present invention is achieved in that the preparation is that medicine is added in the symphysis unit composition Powder, tablet, granule, capsule, liquid preparation, liniment is made in acceptable auxiliary material on.
The third object of the present invention is achieved in that prepared by anti-oxidant, anti-aging the symphysis unit composition Application in anti-oxidant, anti-aging drug, health food or skin care item.
The instructions of taking of anti-oxidant, anti-aging symphysis unit composition of the present invention, the instructions of taking are one Day 1~2 time, 10~20g every time.
The entitled Lactobacillus acidophilus of Latin of the lactobacillus acidophilus.
The entitled Lactobacillus breris of Latin of the Lactobacillus brevis.
The entitled Lactobacillus buchneri of Latin of the lactobacillus buchneri.
The entitled L.casei of Latin of the Lactobacillus casei.
The entitled L.paracasei of Latin of the Lactobacillus paracasei.
The entitled L.curvatus of Latin of the lactobacillus curvatus.
The entitled L.bulbaricus of Latin of the lactobacillus bulgaricus.
The entitled L.debrueckii of Latin of the Lactobacillus delbrueckii.
The entitled L.plantarum of Latin of the lactobacillus plantarum.
The entitled L.salivarius of Latin of the Lactobacillus salivarius.
The entitled Bacillus subtilis of Latin of the bacillus subtilis.
The entitled B.lincheniformis of Latin of the bacillus licheniformis.
The entitled B.coagulans of Latin of the bacillus coagulans.
The entitled B.natto of Latin of the bafillus natto.
The entitled B.adolescebntils of Latin of the bifidobacterium adolescentis.
The entitled B.bifidum of Latin of the bifidobacterium bifidum.
The entitled Enterococcusfaecalis of Latin of the enterococcus faecalis.
The entitled E.faecium of Latin of the enterococcus faecium.
The entitled Lactococus lactis of Latin of the Lactococcus lactis.
The entitled Clostridium butyricum of Latin of the clostridium butyricum.
The entitled Pediococcus acidilactici of Latin of the Pediococcus acidilactici.
The entitled Monascuspurpureus of Latin of the monascus ruber.
Compared with prior art, beneficial effects of the present invention:
1, symphysis unit composition of the invention effectively enhances effect by the rational proportion between probiotics and prebiotics, prebiotic Member can be effectively increased the probiotics quantity in composition, extend the term of validity of symphysis unit, not only so that its is efficacy lasting, but also Promote survival rate of the probiotics in enteron aisle, and prebiotics can digest while as external source probio food entering The competitive growth for promoting exogenous probiotics and endogenous probiotics after system simultaneously, inhibits pathogenic bacteria therein, realizes The effect of removing gastrointestinal tract toxin, reduces the generation of free radical, anti-aging.
2, symphysis unit composition of the present invention can effectively reduce the generation of interior free yl, slow down aging, pass through science The combination of selection probiotics and prebiotics and composition proportion appropriate make the symphysis unit composition clear efficacy notable, at Divide safely and effectively, material matching is reasonable.
3, symphysis unit of the invention effectively facilitates intestinal health, removes toxin, protects intestinal mucosa, maintains mycoderm barrier, will The a large amount of harmful substances such as bacterium and toxin are confined in enteric cavity in enteron aisle, while inhibiting the generation of pathogenic bacteria and toxin, are removed Toxin keeps intestinal health, reduces the generation of free radical.
4, the present invention obtains the material composition proportioning of science through a large number of experiments, is targetedly selected according to application crowd The optimum composition method for selecting probiotics and prebiotics, by scientific and effective proportioning so that symphysis unit composition performance is maximum Effect so that the present invention can not only effectively realize its effect, and selected prebiotics can the benefit arranged in pairs or groups of effective stimulus Raw bacterium proliferation, reasonable composition.
5, instructions of taking dosage of the invention is reasonable, and obvious effect effectively prevents existing probiotics preparation dosage not It to no effect or takes after being taken caused by clear and is excessively possible to the ill effect brought.
6, symphysis unit composition of the invention can both play the physiological bacterial activity of probiotics, and cooperation prebiotics are again optional The quantity for quickly increasing to selecting property probiotics, makes that probiotic action speed is fast and effect is lasting, to play simultaneously probiotics and The physiological function of prebiotics;The present invention also has the advantages that significant effect, quick, safe.
Specific implementation mode
With reference to embodiment, the present invention is further illustrated, but is not limited in any way to the present invention, Based on present invention teach that made by it is any transform or replace, all belong to the scope of protection of the present invention.
Embodiment 1
A kind of anti-oxidant, anti-aging symphysis unit composition, including prebiotics and probiotics, the prebiotics and probiotics Weight ratio is 1:10.
Embodiment 2
A kind of anti-oxidant, anti-aging symphysis unit composition, including prebiotics and probiotics, the prebiotics and probiotics Weight ratio is 10:1.
Embodiment 3
A kind of anti-oxidant, anti-aging symphysis unit composition, including prebiotics and probiotics, the prebiotics and probiotics Weight ratio is 9:2.
Embodiment 4
A kind of anti-oxidant, anti-aging symphysis unit composition, including prebiotics and probiotics, the prebiotics and probiotics Weight ratio is 2:9.
Embodiment 5
A kind of anti-oxidant, anti-aging symphysis unit composition, including prebiotics and probiotics, the prebiotics and probiotics Weight ratio is 7.5:3.
Embodiment 6
A kind of anti-oxidant, anti-aging symphysis unit composition, including prebiotics and probiotics, the prebiotics and probiotics Weight ratio is 3:7.5.
Embodiment 7
A kind of anti-oxidant, anti-aging symphysis unit composition, including prebiotics and probiotics, the prebiotics and probiotics Weight ratio is 5:4.
Embodiment 8
A kind of anti-oxidant, anti-aging symphysis unit composition, including prebiotics and probiotics, the prebiotics and probiotics Weight ratio is 3:1.
Embodiment 9
A kind of anti-oxidant, anti-aging symphysis unit composition, including prebiotics and probiotics, the prebiotics and probiotics Weight ratio is 1:7.
Embodiment 10
A kind of anti-oxidant, anti-aging symphysis unit composition, including prebiotics and probiotics, the prebiotics and probiotics Weight ratio is 1:1.
Embodiment 11
Anti-oxidant, anti-aging symphysis unit composition as described in Example 1, the prebiotics include following weight percent Ingredient:Trehalose 6%, raffinose 1%, xylo-oligosaccharide 14%, oligoisomaltose 1%, oligofructose 6%, oligomeric gala Sugar 1%, chitosan oligosaccharide 9%, soyabean oligosaccharides 8%, synanthrin 16%, aloe polysaccharide 11%, konjac polysaccharide 27%.
Embodiment 12
Anti-oxidant, anti-aging symphysis unit composition as described in Example 2, the prebiotics include following weight percent Ingredient:Trehalose 9%, raffinose 4%, xylo-oligosaccharide 17%, oligoisomaltose 4%, oligofructose 9%, oligomeric gala Sugar 1%, chitosan oligosaccharide 6%, soyabean oligosaccharides 5%, synanthrin 13%, aloe polysaccharide 8%, konjac polysaccharide 24%.
Embodiment 13
Anti-oxidant, anti-aging symphysis unit composition as described in Example 3, the prebiotics include following weight percent Ingredient:Trehalose 7.3%, raffinose 2.4%, xylo-oligosaccharide 15.9%, oligoisomaltose 2.4%, oligofructose 7.3%, galactooligosaccharide 1.2%, chitosan oligosaccharide 7.3%, soyabean oligosaccharides 6.1%, synanthrin 14.6%, aloe polysaccharide 9.8%, evil spirit Taro polysaccharide 25.6%.
Embodiment 14
Anti-oxidant, anti-aging symphysis unit composition as described in Example 4, the prebiotics include following weight percent Ingredient:Trehalose 7%, raffinose 2%, xylo-oligosaccharide 15%, oligoisomaltose 2%, oligofructose 7%, oligomeric gala Sugar 1%, chitosan oligosaccharide 8%, soyabean oligosaccharides 7%, synanthrin 15%, aloe polysaccharide 10%, konjac polysaccharide 26%.
Embodiment 15
Anti-oxidant, anti-aging symphysis unit composition as described in Example 5, the prebiotics include following weight percent Ingredient:Trehalose 8%, raffinose 3%, xylo-oligosaccharide 16%, oligoisomaltose 3%, oligofructose 8%, oligomeric gala Sugar 1%, chitosan oligosaccharide 7%, soyabean oligosaccharides 6%, synanthrin 14%, aloe polysaccharide 9%, konjac polysaccharide 25%.
Embodiment 16
Anti-oxidant, anti-aging symphysis unit composition as described in Example 6, the prebiotics include following weight percent Ingredient:Trehalose 8.5%, raffinose 3.5%, xylo-oligosaccharide 15.9%, oligoisomaltose 3.5%, oligofructose 7.3%, galactooligosaccharide 0.5%, chitosan oligosaccharide 7.3%, soyabean oligosaccharides 6.9%, synanthrin 13%, aloe polysaccharide 8%, konjaku are more Sugar 25.6%.
Embodiment 17
Anti-oxidant, anti-aging symphysis unit composition as described in Example 7, the prebiotics include following weight percent Ingredient:Trehalose 8%, raffinose 4%, xylo-oligosaccharide 17%, oligoisomaltose 2.4%, oligofructose 9%, oligomeric half Lactose 2.5%, chitosan oligosaccharide 6%, soyabean oligosaccharides 6.1%, synanthrin 13%, aloe polysaccharide 8%, konjac polysaccharide 24%.
Embodiment 18
Anti-oxidant, anti-aging symphysis unit composition as described in Example 8, the prebiotics include following weight percent Ingredient:Trehalose 7%, raffinose 2%, xylo-oligosaccharide 15%, oligoisomaltose 2%, oligofructose 7%, oligomeric gala Sugar 1.2%, chitosan oligosaccharide 8%, soyabean oligosaccharides 7%, synanthrin 15%, aloe polysaccharide 9.8%, konjac polysaccharide 26%.
Embodiment 19
Anti-oxidant, anti-aging symphysis unit composition as described in Example 9, the prebiotics include following weight percent Ingredient:It is trehalose 7.5%, raffinose 2.1%, xylo-oligosaccharide 15%, oligoisomaltose 2%, oligofructose 7%, oligomeric Galactolipin 2%, chitosan oligosaccharide 8%, soyabean oligosaccharides 6.1%, synanthrin 14.6%, aloe polysaccharide 9.7%, konjac polysaccharide 26%.
Embodiment 20
Anti-oxidant, anti-aging symphysis unit composition as described in Example 10, the prebiotics include following weight percent The ingredient of ratio:Trehalose 7.3%, raffinose 2.1%, xylo-oligosaccharide 15%, oligoisomaltose 2%, oligofructose 7.1%, Galactooligosaccharide 1.5%, chitosan oligosaccharide 8%, soyabean oligosaccharides 5.8%, synanthrin 15.5%, aloe polysaccharide 9.7%, konjac polysaccharide 26%.
Embodiment 21
A kind of anti-oxidant, anti-aging symphysis unit composition, the prebiotics include the ingredient of following weight percent:Seaweed Sugar 6.5%, raffinose 2.4%, xylo-oligosaccharide 16.5%, oligoisomaltose 3.5%, oligofructose 6.5%, galactooligosaccharide 1.5%, chitosan oligosaccharide 6.5%, soyabean oligosaccharides 6%, synanthrin 14.8%, aloe polysaccharide 9.7%, konjac polysaccharide 26.1%.
Embodiment 22
Anti-oxidant, anti-aging symphysis unit composition as described in Example 1, the probiotics includes following weight percent Ingredient:Lactobacillus acidophilus 0.5%, Lactobacillus brevis 0.4%, lactobacillus buchneri 0.4%, Lactobacillus casei 7%, secondary cheese breast bar Bacterium 0.5%, lactobacillus curvatus 0.4%, lactobacillus bulgaricus 0.4%, Lactobacillus delbrueckii 0.4%, lactobacillus plantarum 14%, saliva Liquid lactobacillus 0.4%, bacillus subtilis 27%, bacillus licheniformis 6%, bacillus coagulans 6%, bafillus natto 8%, bifidobacterium adolescentis 1.2%, bifidobacterium bifidum 1.2%, enterococcus faecalis 1.2%, enterococcus faecium 5%, Lactococcus lactis 5%, clostridium butyricum 2.5%, Pediococcus acidilactici 2.5%, monascus ruber 10%.
Embodiment 23
Anti-oxidant, anti-aging symphysis unit composition as described in Example 2, the probiotics includes following weight percent Ingredient:Lactobacillus acidophilus 3%, Lactobacillus brevis 1.2%, lactobacillus buchneri 1.2%, Lactobacillus casei 9%, Lactobacillus paracasei 2.5%, lactobacillus curvatus 1.2%, lactobacillus bulgaricus 1.2%, Lactobacillus delbrueckii 1.2%, lactobacillus plantarum 17%, saliva Lactobacillus 1.2%, bacillus subtilis 30%, bacillus licheniformis 8%, bacillus coagulans 5.1%, bafillus natto 5%, bifidobacterium adolescentis 0.4%, bifidobacterium bifidum 0.4%, enterococcus faecalis 0.4%, enterococcus faecium 2%, Lactococcus lactis 2%, clostridium butyricum 0.5%, Pediococcus acidilactici 0.5%, monascus ruber 7%.
Embodiment 24
Anti-oxidant, anti-aging symphysis unit composition as described in Example 3, the probiotics includes following weight percent Ingredient:Lactobacillus acidophilus 1.5%, Lactobacillus brevis 0.8%, lactobacillus buchneri 0.8%, Lactobacillus casei 8%, secondary cheese breast bar Bacterium 1.5%, lactobacillus curvatus 0.8%, lactobacillus bulgaricus 0.8%, Lactobacillus delbrueckii 0.8%, lactobacillus plantarum 15.5%, Lactobacillus salivarius 0.8%, bacillus subtilis 28.5%, bacillus licheniformis 7%, bacillus coagulans 4.5%, natto gemma Bacillus 6.5%, bifidobacterium adolescentis 0.8%, bifidobacterium bifidum 0.8%, enterococcus faecalis 0.8%, enterococcus faecium 3.5%, breast Yogurt coccus 3.5%, clostridium butyricum 1.5%, Pediococcus acidilactici 1.5%, monascus ruber 9.8%.
Embodiment 25
Anti-oxidant, anti-aging symphysis unit composition as described in Example 4, the probiotics includes following weight percent Ingredient:Lactobacillus acidophilus 1%, Lactobacillus brevis 0.6%, lactobacillus buchneri 0.6%, Lactobacillus casei 8%, Lactobacillus paracasei 1%, lactobacillus curvatus 0.6%, lactobacillus bulgaricus 0.6%, Lactobacillus delbrueckii 0.6%, lactobacillus plantarum 15%, saliva breast Bacillus 0.6%, bacillus subtilis 28.4%, bacillus licheniformis 7%, bacillus coagulans 5%, bafillus natto 7%, Bifidobacterium adolescentis 1%, bifidobacterium bifidum 1%, enterococcus faecalis 1%, enterococcus faecium 4%, Lactococcus lactis 4%, butyric acid shuttle Bacterium 2%, Pediococcus acidilactici 2%, monascus ruber 9%.
Embodiment 26
Anti-oxidant, anti-aging symphysis unit composition as described in Example 5, the probiotics includes following weight percent Ingredient:Lactobacillus acidophilus 2%, Lactobacillus brevis 1%, lactobacillus buchneri 1%, Lactobacillus casei 9%, Lactobacillus paracasei 2%, It is lactobacillus curvatus 1%, lactobacillus bulgaricus 1%, Lactobacillus delbrueckii 1%, lactobacillus plantarum 16%, Lactobacillus salivarius 1%, withered Careless bacillus 29%, bacillus licheniformis 7%, bacillus coagulans 5.2%, bafillus natto 6%, bifidobacterium adolescentis 0.6%, bifidobacterium bifidum 0.6%, enterococcus faecalis 0.6%, enterococcus faecium 3%, Lactococcus lactis 3%, clostridium butyricum 1%, Pediococcus acidilactici 1%, monascus ruber 8%.
Embodiment 27
Anti-oxidant, anti-aging symphysis unit composition as described in Example 6, the probiotics includes following weight percent Ingredient:Lactobacillus acidophilus 2.5%, Lactobacillus brevis 0.4%, lactobacillus buchneri 0.4%, Lactobacillus casei 8.4%, secondary cheese breast Bacillus 0.5%, lactobacillus curvatus 0.4%, lactobacillus bulgaricus 0.4%, Lactobacillus delbrueckii 0.4%, lactobacillus plantarum 16.5%, Lactobacillus salivarius 0.4%, bacillus subtilis 29.5%, bacillus licheniformis 5%, bacillus coagulans 5.5%, Bafillus natto 7.5%, bifidobacterium adolescentis 0.4%, bifidobacterium bifidum 0.4%, enterococcus faecalis 0.4%, enterococcus faecium 4.5%, Lactococcus lactis 4.5%, clostridium butyricum 2%, Pediococcus acidilactici 1.6%, monascus ruber 8.4%.
Embodiment 28
Anti-oxidant, anti-aging symphysis unit composition as described in Example 7, the probiotics includes following weight percent Ingredient:Lactobacillus acidophilus 0.5%, Lactobacillus brevis 0.4%, lactobacillus buchneri 0.4%, Lactobacillus casei 7.5%, secondary cheese breast Bacillus 2.5%, lactobacillus curvatus 0.4%, lactobacillus bulgaricus 0.4%, Lactobacillus delbrueckii 0.4%, lactobacillus plantarum 15.3%, Lactobacillus salivarius 1.2%, bacillus subtilis 28.7%, bacillus licheniformis 8%, bacillus coagulans 3%, receive Beans bacillus 8%, bifidobacterium adolescentis 0.4%, bifidobacterium bifidum 0.4%, enterococcus faecalis 0.4%, enterococcus faecium 3.8%, Lactococcus lactis 3.8%, clostridium butyricum 2.5%, Pediococcus acidilactici 2%, monascus ruber 10%.
Embodiment 29
Anti-oxidant, anti-aging symphysis unit composition as described in Example 8, the probiotics includes following weight percent Ingredient:Lactobacillus acidophilus 1%, Lactobacillus brevis 0.65%, lactobacillus buchneri 0.65%, Lactobacillus casei 8.5%, secondary cheese breast Bacillus 1%, lactobacillus curvatus 0.9%, lactobacillus bulgaricus 0.9%, Lactobacillus delbrueckii 0.9%, lactobacillus plantarum 16.5%, Lactobacillus salivarius 0.9%, bacillus subtilis 28%, bacillus licheniformis 6.9%, bacillus coagulans 4%, natto gemma bar Bacterium 6.9%, bifidobacterium adolescentis 0.9%, bifidobacterium bifidum 0.9%, enterococcus faecalis 0.9%, enterococcus faecium 4.5%, lactic acid Galactococcus 4.5%, clostridium butyricum 1.3%, Pediococcus acidilactici 1.3%, monascus ruber 8%.
Embodiment 30
Anti-oxidant, anti-aging symphysis unit composition as described in Example 9, the probiotics includes following weight percent Ingredient:Lactobacillus acidophilus 2%, Lactobacillus brevis 1%, lactobacillus buchneri 1%, Lactobacillus casei 8.4%, Lactobacillus paracasei 1.5%, lactobacillus curvatus 0.8%, lactobacillus bulgaricus 0.8%, Lactobacillus delbrueckii 0.8%, lactobacillus plantarum 15.3%, saliva Liquid lactobacillus 0.8%, bacillus subtilis 29%, bacillus licheniformis 7%, bacillus coagulans 4%, bafillus natto 7%, bifidobacterium adolescentis 0.8%, bifidobacterium bifidum 0.8%, enterococcus faecalis 0.8%, enterococcus faecium 3.8%, Lactococcus lactis Bacterium 3.8%, clostridium butyricum 1.5%, Pediococcus acidilactici 1%, monascus ruber 8.1%.
Embodiment 31
Anti-oxidant, anti-aging symphysis unit composition as described in Example 10, the probiotics includes following weight percent The ingredient of ratio:Lactobacillus acidophilus 2%, Lactobacillus brevis 1%, lactobacillus buchneri 1%, Lactobacillus casei 8%, Lactobacillus paracasei 1.5%, lactobacillus curvatus 1%, lactobacillus bulgaricus 1%, Lactobacillus delbrueckii 0.8%, lactobacillus plantarum 15.5%, saliva breast Bacillus 0.8%, bacillus subtilis 28.5%, bacillus licheniformis 7%, bacillus coagulans 4.5%, bafillus natto 6.5%, bifidobacterium adolescentis 0.8%, bifidobacterium bifidum 0.8%, enterococcus faecalis 0.8%, enterococcus faecium 3.5%, lactic acid breast Coccus 3.5%, clostridium butyricum 1.5%, Pediococcus acidilactici 1.5%, monascus ruber 8.5%.
Embodiment 32
A kind of anti-oxidant, anti-aging symphysis unit composition, including prebiotics and probiotics, wherein the probiotics includes The ingredient of following weight percent:Lactobacillus acidophilus 1.8%, Lactobacillus brevis 0.6%, lactobacillus buchneri 0.6%, Lactobacillus casei 8.4%, Lactobacillus paracasei 1.5%, lactobacillus curvatus 0.6%, lactobacillus bulgaricus 0.6%, Lactobacillus delbrueckii 0.6%, Lactobacillus plantarum 15.4%, Lactobacillus salivarius 0.6%, bacillus subtilis 29%, bacillus licheniformis 7%, condensation gemma bar Bacterium 4.6%, bafillus natto 7.5%, bifidobacterium adolescentis 0.6%, bifidobacterium bifidum 0.6%, enterococcus faecalis 0.6%, Enterococcus faecium 4%, Lactococcus lactis 4%, clostridium butyricum 1.5%, Pediococcus acidilactici 1.5%, monascus ruber 8.4%.
Embodiment 33
A kind of anti-oxidant, anti-aging symphysis unit composition, including prebiotics and probiotics, wherein the probiotics includes The ingredient of following weight percent:Lactobacillus acidophilus 2.5%, Lactobacillus brevis 1%, lactobacillus buchneri 1%, Lactobacillus casei 7.5%, Lactobacillus paracasei 2.5%, lactobacillus curvatus 1.2%, lactobacillus bulgaricus 1.2%, Lactobacillus delbrueckii 1.2%, Lactobacillus plantarum 15.7%, Lactobacillus salivarius 0.9%, bacillus subtilis 28.8%, bacillus licheniformis 7.8%, condensation bud Spore bacillus 4.8%, bafillus natto 6.8%, bifidobacterium adolescentis 1.1%, bifidobacterium bifidum 1.1%, enterococcus faecalis 1.1%, enterococcus faecium 3.6%, Lactococcus lactis 2.2%, clostridium butyricum 0.5%, Pediococcus acidilactici 0.5%, monascus ruber 7%.
Embodiment 34
A kind of anti-oxidant, anti-aging symphysis unit composition, including prebiotics and probiotics, wherein the probiotics includes The ingredient of following weight percent:Lactobacillus acidophilus 3%, Lactobacillus brevis 1.2%, lactobacillus buchneri 1.2%, Lactobacillus casei 27%, Lactobacillus paracasei 2.5%, lactobacillus curvatus 1.2%, lactobacillus bulgaricus 1.2%, Lactobacillus delbrueckii 1.2%, plant Object lactobacillus 57.9%, Lactobacillus salivarius 1.2%, bacillus subtilis 0%, bacillus licheniformis 0%, bacillus coagulans 0%, bafillus natto 0%, bifidobacterium adolescentis 1.2%, bifidobacterium bifidum 1.2%, enterococcus faecalis 0%, enterococcus faecium 0%, Lactococcus lactis 0%, clostridium butyricum 0%, Pediococcus acidilactici 0%, monascus ruber 0%.
Embodiment 35
A kind of preparation of anti-oxidant, anti-aging symphysis unit composition, the preparation are described anti-oxidant, anti-aging Pharmaceutically acceptable auxiliary material is added in symphysis unit composition, powder is made.
Application of anti-oxidant, anti-aging the symphysis unit composition in preparing oxidation resistant drug.
Embodiment 36
A kind of preparation of anti-oxidant, anti-aging symphysis unit composition, the preparation are described anti-oxidant, anti-aging Pharmaceutically acceptable auxiliary material is added in symphysis unit composition, tablet is made.
Application of anti-oxidant, anti-aging the symphysis unit composition in preparing oxidation-resisting health-care food.
Embodiment 37
A kind of preparation of anti-oxidant, anti-aging symphysis unit composition, the preparation are described anti-oxidant, anti-aging Pharmaceutically acceptable auxiliary material is added in symphysis unit composition, granule is made.
Application of anti-oxidant, anti-aging the symphysis unit composition in preparing oxidation resistant skin care item.
Embodiment 38
A kind of preparation of anti-oxidant, anti-aging symphysis unit composition, the preparation are described anti-oxidant, anti-aging Pharmaceutically acceptable auxiliary material is added in symphysis unit composition, capsule is made.
Application of anti-oxidant, anti-aging the symphysis unit composition in the drug for preparing anti-aging.
Embodiment 39
A kind of preparation of anti-oxidant, anti-aging symphysis unit composition, the preparation are described anti-oxidant, anti-aging Pharmaceutically acceptable auxiliary material is added in symphysis unit composition, liquid preparation is made.
Application of anti-oxidant, anti-aging the symphysis unit composition in the health food for preparing anti-aging.
Embodiment 40
A kind of preparation of anti-oxidant, anti-aging symphysis unit composition, the preparation are described anti-oxidant, anti-aging Pharmaceutically acceptable auxiliary material is added in symphysis unit composition, liniment is made.
Application of anti-oxidant, anti-aging the symphysis unit composition in the skin care item for preparing anti-aging.
Embodiment 41
Experimental example:Wu so-and-so, female, Zhaotong County, Yunnan people, 48 years old, skin of face color spot was apparent, uninterruptedly takes the present invention and prepares Symphysis unit composition tablet, two times a day, each 10g, after taking 60 days, facial colour spot is obviously desalinated, and naked eyes hardly may be used See.
Embodiment 42
Experimental example:So-and-so is applied, female, Yunnan people from Pu'er, 53 years old, complexion was obviously turned to be yellow, and uninterruptedly took symphysis prepared by the present invention First composition capsule, once a day, each 20g, after taking 90 days, complexion turn to be yellow the problem of thoroughly solve, having rosy cheeks has Gloss.
Embodiment 43
Experimental example:Mr. Li, male, Honghe, Yunnan people, 63 years old, senile plaque uninterruptedly took symphysis unit combination prepared by the present invention Composition granule agent, 2 times a day, a 15g, after being used continuously 90 days, situation is clearly better, and senile plaque desalination has no new old age Spot generates.

Claims (10)

1. a kind of anti-oxidant, anti-aging symphysis unit composition, it is characterised in that anti-oxidant, anti-aging the symphysis tuple It includes prebiotics and probiotics to close object, and the weight ratio of the prebiotics and probiotics is 1~10:1~10.
2. anti-oxidant, anti-aging symphysis unit composition according to claim 1, it is characterised in that the prebiotics with The weight ratio of probiotics is 3~10:1.
3. anti-oxidant, anti-aging symphysis unit composition according to claim 1, it is characterised in that the prebiotics with The weight ratio of probiotics is 1:1~7.
4. anti-oxidant, anti-aging symphysis unit composition according to claim 1, it is characterised in that the prebiotics packet Include the ingredient of following weight percent:Trehalose 6~9%, raffinose 1~4%, xylo-oligosaccharide 14~17%, oligomeric different malt Sugar 1~4%, oligofructose 6~9%, galactooligosaccharide 0.5~2.5%, chitosan oligosaccharide 6~9%, soyabean oligosaccharides 5~8%, chrysanthemum Sugar 13~16%, aloe polysaccharide 8~11%, konjac polysaccharide 24~27%.
5. anti-oxidant, anti-aging symphysis unit composition according to claim 1, it is characterised in that the prebiotics packet Include the ingredient of following weight percent:Trehalose 7~8%, raffinose 2~3%, xylo-oligosaccharide 15~16%, oligomeric different malt Sugar 2~3%, oligofructose 7~8%, galactooligosaccharide 1~2%, chitosan oligosaccharide 7~8%, soyabean oligosaccharides 6~7%, synanthrin 14 ~15%, aloe polysaccharide 9~10%, konjac polysaccharide 25~26%.
6. anti-oxidant, anti-aging symphysis unit composition according to claim 1, it is characterised in that the prebiotic bacterium bag Include the ingredient of following weight percent:Lactobacillus acidophilus 0.5~3%, Lactobacillus brevis 0.4~1.2%, lactobacillus buchneri 0.4~ 1.2%, Lactobacillus casei 7~27%, Lactobacillus paracasei 0.5~2.5%, lactobacillus curvatus 0.4~1.2%, Bulgaria Lactobacillus 0.4~1.2%, Lactobacillus delbrueckii 0.4~1.2%, lactobacillus plantarum 14~57.9%, Lactobacillus salivarius 0.4~ 1.2%, bacillus subtilis 0~30%, bacillus licheniformis 0~8%, bacillus coagulans 0~6%, bafillus natto 0 ~8%, bifidobacterium adolescentis 0.4~1.2%, bifidobacterium bifidum 0.4~1.2%, enterococcus faecalis 0~1.2%, enterococcus faecium 0~5%, Lactococcus lactis 0~5%, clostridium butyricum 0~2.5%, Pediococcus acidilactici 0~2.5%, monascus ruber 0~10%.
7. anti-oxidant, anti-aging symphysis unit composition according to claim 1, it is characterised in that the prebiotic bacterium bag Include the ingredient of following weight percent:Lactobacillus acidophilus 1~2%, Lactobacillus brevis 0.6~1%, lactobacillus buchneri 0.6~1%, Lactobacillus casei 8~9%, Lactobacillus paracasei 1~2%, lactobacillus curvatus 0.6~1%, lactobacillus bulgaricus 0.6~ 1%, Lactobacillus delbrueckii 0.6~1%, lactobacillus plantarum 15~16%, Lactobacillus salivarius 0.6~1%, bacillus subtilis 28~ 29%, bacillus licheniformis 6~7%, bacillus coagulans 4~5%, bafillus natto 6~7%, bifidobacterium adolescentis 0.6 ~1%, bifidobacterium bifidum 0.6~1%, enterococcus faecalis 0.6~1%, enterococcus faecium 3~4%, Lactococcus lactis 3~4%, Clostridium butyricum 1~2%, Pediococcus acidilactici 1~2%, monascus ruber 8~9%.
8. a kind of preparation according to any anti-oxidant, anti-aging the symphysis unit composition of claim 1~7, feature It is that the preparation is that pharmaceutically acceptable auxiliary material is added in anti-oxidant, anti-aging the symphysis unit composition Powder, tablet, granule, capsule, liquid preparation, liniment is made.
9. a kind of application according to any anti-oxidant, anti-aging the symphysis unit composition of claim 1~7, feature It is that anti-oxidant, anti-aging the symphysis unit composition is preparing anti-oxidant, anti-aging drug, health food or skin care Application in product.
10. a kind of instructions of taking according to any anti-oxidant, anti-aging the symphysis unit composition of claim 1~7, It is characterized in that the instructions of taking of anti-oxidant, anti-aging the symphysis unit composition is 1~2 time on the one, every time 10~20g.
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Cited By (6)

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WO2020082220A1 (en) * 2018-10-23 2020-04-30 利时雨 Enterococcus faecalis having resistance to cephalosporin and high expression of sirtuin 2-like protein and use thereof
CN112772932A (en) * 2020-12-31 2021-05-11 然益科技(深圳)有限公司 Anti-aging hair-nourishing probiotic powder and preparation method thereof
CN112998276A (en) * 2021-02-01 2021-06-22 天津科技大学 Synbiotic compound preparation for preventing diarrhea, intestinal leakage and sepsis caused by excessive ingestion of prebiotics, preparation method and application
CN114306393A (en) * 2020-09-30 2022-04-12 王忠诚 New medicine capable of treating cramp, strengthening body and delaying senility and its prepn
CN115349619A (en) * 2022-08-09 2022-11-18 山东莺歌食品有限公司 Probiotics and prebiotics peanut butter
CN116173075A (en) * 2022-10-17 2023-05-30 西北农林科技大学 Synbiotic composition for improving cognitive function based on clostridium sporogenes and application thereof

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2020082220A1 (en) * 2018-10-23 2020-04-30 利时雨 Enterococcus faecalis having resistance to cephalosporin and high expression of sirtuin 2-like protein and use thereof
CN114306393A (en) * 2020-09-30 2022-04-12 王忠诚 New medicine capable of treating cramp, strengthening body and delaying senility and its prepn
CN112772932A (en) * 2020-12-31 2021-05-11 然益科技(深圳)有限公司 Anti-aging hair-nourishing probiotic powder and preparation method thereof
CN112998276A (en) * 2021-02-01 2021-06-22 天津科技大学 Synbiotic compound preparation for preventing diarrhea, intestinal leakage and sepsis caused by excessive ingestion of prebiotics, preparation method and application
CN112998276B (en) * 2021-02-01 2023-08-29 天津科技大学 Synbiotic compound preparation for preventing diarrhea, intestinal leakage and sepsis caused by excessive intake of prebiotics, preparation method and application
CN115349619A (en) * 2022-08-09 2022-11-18 山东莺歌食品有限公司 Probiotics and prebiotics peanut butter
CN116173075A (en) * 2022-10-17 2023-05-30 西北农林科技大学 Synbiotic composition for improving cognitive function based on clostridium sporogenes and application thereof

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