CN108567508A - Intraocular implant - Google Patents
Intraocular implant Download PDFInfo
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- CN108567508A CN108567508A CN201710131169.4A CN201710131169A CN108567508A CN 108567508 A CN108567508 A CN 108567508A CN 201710131169 A CN201710131169 A CN 201710131169A CN 108567508 A CN108567508 A CN 108567508A
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- Prior art keywords
- component
- layer
- intraocular implant
- intraocular
- implant according
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/14—Eye parts, e.g. lenses, corneal implants; Implanting instruments specially adapted therefor; Artificial eyes
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B33—ADDITIVE MANUFACTURING TECHNOLOGY
- B33Y—ADDITIVE MANUFACTURING, i.e. MANUFACTURING OF THREE-DIMENSIONAL [3-D] OBJECTS BY ADDITIVE DEPOSITION, ADDITIVE AGGLOMERATION OR ADDITIVE LAYERING, e.g. BY 3-D PRINTING, STEREOLITHOGRAPHY OR SELECTIVE LASER SINTERING
- B33Y80/00—Products made by additive manufacturing
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2240/00—Manufacturing or designing of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2240/001—Designing or manufacturing processes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2250/00—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2250/0014—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof having different values of a given property or geometrical feature, e.g. mechanical property or material property, at different locations within the same prosthesis
- A61F2250/005—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof having different values of a given property or geometrical feature, e.g. mechanical property or material property, at different locations within the same prosthesis differing in colour
Abstract
The present invention discloses a kind of intraocular implants, the intraocular implant includes the first component and second component, the circumferential edge of the first component and the circumferential edge of the second component are connected with each other to form pouch between the first component and the second component, the pouch is for accommodating intraocular lens, wherein, the first component includes the first disk, and first disk has centrally located elliptical aperture；And the second component includes the second disk, and second disk has centrally located circular hole.
Description
Technical field
The present invention relates to field of medical equipment more particularly to a kind of intraocular implant, which after the implantation may be used
The korectomia moved after forming position and the pouch space for accommodating and fixing intraocular lens.
Background technology
Iris is to belong to eyeball middle level, in front of ciliary body, there is the size of automatic adjustment pupil, adjusts and enter intraocular light
How many effects.The pupil of normal eye is in 3.5-4.5mm, when daytime, light was strong, myosis, and at night, light
When weak, pupil expand, by automatically adjust pupil size variation, can control into human eye light number, human eye
Different light environments can be adapted to rapidly.If human eye leads to aniridia or iridocoloboma because of wound or eye congenital anomaly,
Light into human eye is no longer influenced by adjusting and control, and can't keep one's eyes open eyeball under strong light environment, phenomena such as causing dazzle, photophobia.
As a kind of biologic soft tissue material, iris has the viscous-elastic behaviours such as lag, relaxation, creep, strain rate dependency.
The important mechanical characteristic of iris makes it when eye traumas or eye congenital anomaly lead to aniridia or iridocoloboma, it tends to be difficult to repair
It is multiple, there is the dysfunction of eyeball, such as spherical aberration, the increase of aberration, low visual acuity after diplopia, dazzle, photophobia, amblyopia and wound, with
And visual acuity reduction etc..
Since the iris of atrophy cannot be allowed to regenerate at present by means such as drugs, the means of operation can only be used to be repaiied
It mends.Common modus operandi has iris suture to be implanted into artificial iris.Iris suture is the normal iris group using patient's remaining
Iris tissue stretching is stitched together by the elasticity knitted, and plays the role of certain control light and limitation aberration.
The method of best treatment iridocoloboma or missing is implantation intraocular implant artificial iris to replace impaired day
Right iris, the implantation of intraocular implant artificial iris are replaced or all instead of natural rainbow come part using artificial synthesized material
Film.But there is presently no the synthetic material that can replace natural iris completely, current product is all in rigid intraocular implants
One iris of band is every material is polymethyl methacrylate, needs larger operative incision, incision size is mostly in 10mm on body
More than, implantation process is more complicated, and surgical effect and popularization are restricted.Ideal intraocular implant artificial iris material should
With characteristic similar with natural iris, there are the viscous-elastic behaviours such as lag, relaxation, creep, strain rate dependency.
Traumatic injury of iris is often simultaneously with lens damage, and pouch is impaired etc., even if implantable artificial crystalline lens
It can be difficult to fix, therefore often be implanted into intraocular implant artificial iris come when replacing impaired natural iris, it is also necessary to be implanted into people
Work crystalline lens, but since pouch is impaired, at this point, the implantation position of intraocular lens and fixation are a hang-ups.
Currently, the major way of fixed intraocular implant has suture fixed form and button loop supporting way.
Suture fixed form is fixed by bundle of lines implantation material after passing suture through tissue, but the limitation of the above method
Property be that intraocular space is limited, suture within the eye overlap joint is extremely difficult, and surgical procedure difficulty is big, and surgical effect is limited.
Button loop supporting way is limited in closed space at one, and the end of enclosure space is withstood using button loop, plays support
Effect, this modus operandi is simple, easy to operate, for example is fixed in the pouch of intraocular lens, but the limitation of the above method
Property is to perform the operation in closed space, is not particularly suited for the artificial iris class eye in anterior chamber angle or ciliary groove etc.
The fixation of implant and intraocular lens.
Existing intraocular implant artificial iris operation is usually fixed in a manner of suture on the iris of remaining or rainbow
In film root or ciliary groove, which needs to carry out complicated suture in narrow within the eye, closed space and the behaviour that knots
Make, operating difficulty is big, limits the development of operation, makes the patient of numerous iridocolobomas that cannot effectively treat.
Further, since lesion and wound lead to the patient of iris injury, often occur together lenticular disease or wound, no
It only will appear cataract, it is also possible to which the lesion with crystal pouch or damage make artificial lenticular fixed difficulty increase.
Artificial iris is processed at present and intraocular lens mostly use greatly machine and add cutting or molded mode, due to passing
The defect of system processing method itself, the artificial iris for being much designed to have labyrinth have no idea to realize.
In 102090942 A of publication CN, mention with subsequent hyaline membrane and outrunner's work iris every formation
Pouch, pouch also have the protrusion etc. of fixed intraocular lens, using tradition behind artificial iris and pupil inside pouch
Machine add cutting or molded processing method, the class formation be that can not achieve completely.
In addition in 102090942 A of patent CN, the pupil of artificial iris all designs the front surface in implantation material, manually
Crystalline lens fixed structure all designs rear surface or back in artificial iris and pupil, after implantable artificial iris, replants into people
Work crystalline lens becomes extremely difficult, and bad operation and adjustment intraocular lens are placed in the middle etc..
Invention content
To overcome the defects of present in the prior art, the present invention proposes that a kind of intraocular implant, the intraocular implant include
The first component, second component and the pouch formed by the first component and second component.The circumferential edge of the first component and second
The circumferential edge of component is connected with each other to form pouch between the first component and second component, and the pouch is for accommodating artificial crystalline substance
Shape body.
In particular it relates to content below.
According to the present invention, the first component of intraocular implant includes the first disk, and the first disk has centrally located ellipse
Circular hole.According to the present invention, the short axle of elliptical aperture is designed to that as intraocular lens' optical zone dimension size, can play prevents
The effect of dazzle prevents light from being penetrated from the edge of intraocular lens, dazzle is caused using pupil.It is oval according to the present invention
The long axis and short axle in hole, which can be gradually tapered up from the front surface of the first component to the rear surface of the first component, to become smaller.The Vitreous cavity
Object is fixed on by the button loop on the first component in scleral walls, is fixed using button loop or sutured fixed mode being stably fixed to consolidate
Membranous wall, it is reliable and stable, it is easy to operate.
According to the present invention, second component includes the second disk, and there is the second disk centrally located circular hole, the circular hole to be formed
The korectomia moved behind position, the korectomia moved behind the position can provide higher image quality, with reduced size
Korectomia can reach the function of the forward big pupil in position, while can reduce the size of intraocular lens.
According to light propagation principle, pupil is closer with a distance from retina, and the size by pupil needed for same light is smaller,
The pupil size about 3.5-4.5mm or so of human eye under normal circumstances, after moving behind korectomia position with original normal position pupil
Hole size compares, and calculates such as following table：
| Originally pupil size/mm | Distance/mm is moved afterwards | Artificial pupil size/mm after moving afterwards |
| 3.5 | 1.7 | 3.27 |
| 4.0 | 1.7 | 3.74 |
| 4.5 | 1.7 | 4.20 |
| 3.5 | 2.0 | 3.24 |
| 4.0 | 2.0 | 3.70 |
| 4.5 | 2.0 | 4.15 |
| 3.5 | 2.2 | 3.21 |
| 4.0 | 2.2 | 3.67 |
| 4.5 | 2.2 | 4.12 |
Note：1）Originally pupil is located at before crystalline lens, and korectomia is located at after crystalline lens after rear shifting, is close to crystalline lens；
2）Change in size after moving afterwards is related with the crystalline lens number of degrees, is herein that reference is calculated according to the crystal of 20D.
According to the present invention, second component includes curved surface and is connect with the first component via the curved surface at circumferential edge,
To form pouch, as shown in Figure 2.For the pouch there are two opening, first opening of pouch is the elliptical aperture of the first component,
Second opening of pouch is the circular hole of second component, and pouch utilizes intraocular lens for accommodating and fixing intraocular lens
Button loop, intraocular lens can be stably fixed in the pouch that the first component and second component are formed, and intraocular lens are located at
Behind the elliptical aperture of the first component and the circular hole of second component（That is korectomia）Before, the elliptical aperture of the first component is convenient for
The implantation of intraocular lens and position adjustment, intraocular lens can improve optical quality in the front of korectomia.It is artificial brilliant
Shape body is implanted by the elliptical aperture of the first component, easy to operate, securely and reliably.
According to the present invention, a diameter of 9.0-13.0mm and thickness of the first component are 0.2-0.5mm, it is preferable that
The a diameter of 10.0-12.0mm and thickness of the first component are 0.3-0.4mm.
According to the present invention, the length of the long axis of the elliptical aperture is 7.0-9.0mm, and the length of the short axle of the elliptical aperture is
4.5-6.5mm, it is preferable that the length of the long axis of the elliptical aperture is 7.5-8.5mm, and the length of the short axle of the elliptical aperture is
5.0-6.0mm。
According to the present invention, a diameter of 9.0-13.0mm and thickness of the second component are 0.3-0.6mm, it is preferable that
The a diameter of 10.0-12.0mm and thickness of the second component are 0.4-0.5mm.
According to the present invention, a diameter of 2.5-5.0mm of the circular hole of the second component, preferably 3.2-4.2mm.
According to the present invention, the second component includes one or more bellmouths, one or more of bellmouths and institute
The angle for stating second component formation is 30-60 degree, preferably 40-50 degree.
According to the present invention, the internal diameter of the pouch is 8.4-12.4mm, preferably 9.0-11.4mm, and the pouch
Height is 0.3-0.7mm, preferably 0.4-0.5mm.
According to the present invention, the overall thickness of the rear surface of the front surface of the first component to the second component is 0.8-
2.0mm, preferably 1.0-2.0mm, more preferably 1.2-1.5mm.
According to the present invention, when the intraocular implant is implanted intraocular, the front surface elongation film of the first component
2.4-3.7mm。
According to the present invention, the intraocular implant processed in such a way that 3D printing, machine add cutting or die casting and
At.
According to the present invention, the intraocular implant is by can be used for the flexible high molecular material or biomaterial system of Vitreous cavity
At.
According to the present invention, the first component and/or the second component are single layer structures, the first component and/or
The second component be solid color or have multiple color.
According to the present invention, the first component and/or the second component are multi-layer compound structures, the first component
And/or each layer of the multi-layer compound structure of the second component be solid color or have multiple color.
According to the present invention, the first component is three-layer composite structure comprising first layer, the second layer and third layer,
In, the first layer is white, and the second layer is between the first layer and the third layer and is red, brown, blue three
The colored structures of color, the third layer are white.
According to the present invention, the first component is the single layer structure with multiple color, and the second component is three
Layer composite construction comprising first layer, the second layer and third layer, wherein the first layer is white, and the second layer is located at institute
It states between first layer and the third layer and is multiple color, the third layer is white.
According to the present invention, second component has the one or more bellmouths led to for flow of aqueous humor, with second component at one
Determine angle, can be entered by the bellmouth of second component to avoid by the light of the elliptical aperture of the first component and intraocular lens
Intraocular causes dazzle.
According to the present invention, intraocular implant may be used machine and add the mode of cutting and die casting to process.In addition, intraocular
Implantation material can also be processed by the way of 3D printing, and so as to be processed into increasingly complex structure, the machine of solving, which adds, to be cut
Cut the labyrinth that cannot be processed with die casting.
According to the present invention, the first component and/or second component of intraocular implant can be black, blue, brown, green
Or red single layer structure.According to the present invention, the first component and/or second component of intraocular implant can be the compound of multilayer
Structure, the structure and color of each layer can be different, form the gorgeous color of more horn of plenty, meet the different demands of patient.
The personalized customization of patient may be implemented in intraocular implant provided by the invention, can first acquire the iris ruler of patient
The very little, color liked, desired pupil size, after wishing the information such as the size of intraocular lens being implanted into, using 3D printing
The intraocular implant of patient's customization is processed in mode personalization, can more meet the needs of patient.
Intraocular implant provided by the invention can be fabricated from a flexible material, and be planted using smaller notch after can folding
Enter, implantation notch is in 5-6mm or so.
Light transmission rate of the lightproof part of intraocular implant provided by the invention in 300-1100nm wave-length coverages is not
More than 0.54%.
Description of the drawings
Fig. 1 shows the structural schematic diagram of intraocular implant according to the present invention；
Fig. 2 shows the schematic side elevations of intraocular implant according to the present invention；
Fig. 3 shows the schematic diagram of intraocular implant according to an embodiment of the invention, first of the intraocular implant
Part and second component are single layer structure；
Fig. 4 shows the schematic diagram of intraocular implant according to an embodiment of the invention, first of the intraocular implant
Part is single layer structure and second component is three-layer composite structure；
Fig. 5 shows the schematic diagram of intraocular implant according to an embodiment of the invention, first of the intraocular implant
Part is three-layer composite structure；
Fig. 6 shows the schematic diagram of the first component of intraocular implant according to an embodiment of the invention；
Fig. 7 shows the schematic diagram of the elliptical aperture of the first component of intraocular implant according to an embodiment of the invention；
Fig. 8 shows that the elliptical aperture of the first component of intraocular implant according to an embodiment of the invention gradually tapers up and becomes smaller
Schematic diagram；
Fig. 9 shows the schematic diagram of the second component of intraocular implant according to an embodiment of the invention；
Figure 10 shows one or more bellmouths of the second component of intraocular implant according to an embodiment of the invention
Schematic diagram；
Figure 11 schematically show the bellmouth of the second component of intraocular implant according to an embodiment of the invention with
Second component angulation；
Figure 12 schematically shows intraocular lens and is placed on intraocular implant according to an embodiment of the invention
In pouch；And
Figure 13 shows light of the lightproof part for different wave length of intraocular implant according to an embodiment of the invention
Transmitance.
Specific implementation mode
Fig. 1 shows the structural schematic diagram of intraocular implant according to the present invention, and Fig. 2 shows according to the present invention
The schematic side elevation of intraocular implant.As depicted in figs. 1 and 2, intraocular implant according to the present invention include the first component and
Second component.The circumferential edge of the first component and the circumferential edge of second component are connected with each other in the first component and second component
Between form pouch.Pouch is for accommodating intraocular lens.The first component includes the first disk, with centrally located ellipse
Hole.Second component includes the second disk, with centrally located circular hole.
The first component and/or second component of the intraocular implant of the present invention can be single layer structures.The intraocular of the present invention
The first component and/or second component of implantation material can be solid color or can have a multiple color.For example, of the invention
Intraocular implant the first component and/or second component can have black, brown, blue, brown, green, it is red in
It is one or more.
The first component and/or second component of the intraocular implant of the present invention can be multi-layer compound structures.The multilayer is multiple
The each layer for closing structure can be solid color or can have a multiple color.For example, the intraocular implant of the present invention
Each layer of the multi-layer compound structure of the first component and/or second component can have black, brown, blue, brown, green,
It is one or more in red.
The first component and second component of the intraocular implant of one embodiment of the present of invention are all the single layer of such as black
Structure, as shown in Figure 3.
The first component of the intraocular implant of one embodiment of the present of invention is with multiple color（It is i.e. colored）Single layer
Structure.
The first component of the intraocular implant of one embodiment of the present of invention is three-layer composite structure comprising first layer,
The second layer and third layer, wherein first layer is white, the second layer（It is also referred to as intermediate between first layer and third layer
Layer）Can for example, red, brown, Lan Sanse colored structures, third layer be white.In this embodiment, the first of the first component
The white of layer and third layer is the color of material itself, the second layer（Middle layer）For colour, the structure handle of this similar sandwich
Color is enclosed in middle layer, color can be prevented to be precipitated, to can more simulate the color of natural iris, as shown in Figure 4.
The second component of the intraocular implant of one embodiment of the present of invention is three-layer composite structure comprising first layer,
The second layer and third layer, wherein for example, first layer is white, the second layer（It is between first layer and third layer, also referred to as
Middle layer）For multiple color, third layer is white, and the first component is with multiple color（It is i.e. colored）Single layer structure,
As shown in Figure 5.The multi-layer compound structure that the intraocular implant of the present invention can also be combined with other colors and/or color.
In some embodiments, a diameter of 9.0-13.0mm of the first component and thickness are 0.2-0.5mm, it is preferable that
The a diameter of 10.0-12.0mm and thickness of the first component are 0.3-0.4mm.In the Vitreous cavity of one embodiment of the present of invention
In object, the thickness of the first component is 0.3mm, a diameter of 11mm, as shown in Figure 6.
In some embodiments, the length of the long axis of the elliptical aperture of the first component is 7.0-9.0mm, the ellipse of the first component
The length of the short axle in hole is 4.5-6.5mm, it is preferable that the length of the long axis of the elliptical aperture is 7.5-8.5mm, the elliptical aperture
Short axle length be 5.0-6.0mm.In the intraocular implant of one embodiment of the present of invention, the elliptical aperture of the first component
The length of long axis is 8mm, and the length of short axle is 5.5 mm, as shown in Figure 7.
In the intraocular implant of one embodiment of the present of invention, the long axis of the elliptical aperture of the first component and short axle are from first
The front surface of component is gradually tapered up to the rear surface of the first component to become smaller, as shown in Figure 8.For example, in the front surface of the first component
The length of long axis of elliptical aperture be 8.5mm, the length of short axle is 6.0mm, the length of the elliptical aperture in the rear surface of the first component
The length of axis is 8mm, and the length of short axle is 5.5 mm.
In the intraocular implant of one embodiment of the present of invention, second component is black non transparent, can prevent light
Through second component, as shown in Figure 9.In some embodiments, a diameter of 9.0-13.0mm of second component and thickness is
0.3-0.6mm, it is preferable that a diameter of 10.0-12.0mm and thickness of second component are 0.4-0.5mm.The one of the present invention
In the intraocular implant of a embodiment, the thickness of second component is 0.5mm, a diameter of 11mm of second component.
In some embodiments, the overall thickness of the front surface of the first component to the rear surface of second component is 0.8-2.0mm,
Preferably 1.0-2.0mm, more preferably 1.2-1.5mm.In the intraocular implant of one embodiment of the present of invention, from first
The overall thickness of the front surface of part to the rear surface of second component is 1.2mm.
In some embodiments, a diameter of 2.5-5.0mm of the circular hole of second component, preferably 3.2-4.2mm.In this hair
In the intraocular implant of bright one embodiment, a diameter of 3.27mm of the circular hole of second component.In this case, according to preceding
The calculating in face is equal to the size that the korectomia obtained after 1.7mm is moved after the natural pupils of original 3.5mm.
In the intraocular implant of one embodiment of the present of invention, as shown in Figure 10, one or more of second component
Bellmouth, which is gradually tapered up from the rear surface of second component to the front surface of second component, to become smaller.Cone in the rear surface of second component
A diameter of 0.4mm in shape hole, a diameter of 0.3mm of the bellmouth in the front surface of second component.In some embodiments, described
One or more bellmouths are 30-60 degree, preferably 31-45 degree with the angle that the second component is formed.The one of the present invention
In the intraocular implant of a embodiment, one or more bellmouths and the second component angulation of second component are 45 degree.
Bellmouth may be used as the channel of aqueous humor circulation, allow aqueous humor free flow between anterior chamber and back room.All as flow of aqueous humor
The diameter of the bellmouth in road is preferably between 0.3-0.4mm, it is contemplated that the thickness of second component is preferably 0.40-0.50mm, such as
Shown in Figure 11.The preferred value of bellmouth and second component angle can be obtained by simulation, as shown in the table.
| Tapered hole diameter mm | Second component thickness mm | Angle（Degree） |
| 0.30 | 0.40 | 36.1 |
| 0.30 | 0.50 | 31 |
| 0.40 | 0.40 | 45 |
| 0.40 | 0.50 | 38.6 |
In some embodiments, the internal diameter of pouch is 8.4-12.4mm, preferably 9.0-11.4mm, and the height of pouch
For 0.3-0.7mm, preferably 0.4-0.5mm.In the intraocular implant of one embodiment of the present of invention, the first component and second
The internal diameter that component is formed by pouch is that intraocular lens are fixed on first by 10.2mm after the button loop expansion of intraocular lens
In the pouch that part and second component are formed, as shown in figure 12.
In some embodiments, when intraocular implant according to the present invention is implanted intraocular, the front surface of the first component
Elongation film 2.4-3.7mm.
In some embodiments, 3D printing may be used in intraocular implant according to the present invention, machine adds cutting or mold
The mode of casting is process.
In some embodiments, intraocular implant according to the present invention can be by can be used for the flexible macromolecule of Vitreous cavity
Material or biomaterial are made.
In the intraocular implant of one embodiment of the present of invention, the lightproof part of intraocular implant is in 300nm-
Light transmission rate in 1100nm wave-length coverages is not more than 0.54%, as shown in figure 13.
The size of human eye ball is average, and in 11.0mm or so, small also has 9.0mm, and big also having arrives 14.0mm's.In order to
Meet the needs of more patients, it can be the diameter of the first component and second component preferably in a variety of of 10.0-12.0mm
Specification.The anterior chamber depth of human eye is in 2.8mm or so, mostly between 2.4mm ~ 3.7mm, the implantation position of this intraocular implant by
The influence in intraocular space cannot generate intraocular hypertension after implantation, can not corneal damage endothelial cell, therefore entire intraocular implant
Thickness（Distance of the first component front surface to second component rear surface）It is certainly the smaller the better preferably no more than 2.0mm, but
It is that intraocular lens are also placed in the intraocular implant, according to the difference of intraocular lens' focal power（From -10D to+
36D）, center thickness is about 0.20mm ~ 1.2mm（It can difference according to the refraction index different-thickness of material）, so
Intraocular implants' body front surface of biconvex can be embedded into the elliptical aperture of the first component after optimization design, after intraocular lens
Surface is embedded into the korectomia of second component, high so as to reduce the intermediate pouch that the first component and second component are formed
Degree, is calculated using+36D artificial lens, in korectomia's diameter 3.5mm, the pouch height that+36D intraocular lens need
Not less than 0.415mm, pupil diameter is bigger, it is desirable that pouch height it is smaller, intraocular lens' focal power is smaller, it is desirable that pouch
Thickness is smaller, therefore 0.40 ~ 0.50mm of the preferred pouch height of the present invention.Second component needs to meet in 300nm-1100nm wavelength
In range, light transmission rate is less than 1%, could meet the requirement of this intraocular implant, the second component of intraocular implant can be by 3
Layer composition, including transparent or opaque first layer and third layer, intermediate second layer is the lightproof part of multiple color composition；
Certain second component can also meet in 300nm-1100nm wave-length coverages, one layer knot of the light transmission rate less than 1%
Structure, it is contemplated that the structure and performance of second component, the preferably thickness of second component are 0.40-0.50mm；For the first component
Thickness mainly considers structure, intensity and the processing of component, the preferred 0.30-0.40mm of thickness, therefore entire intraocular implant
The preferred 1.2-1.5mm of thickness.
Although reference（It is one or more）Exemplary embodiment describes the present invention, but those skilled in the art will
Understand, the present invention is not limited to precise structure described herein and component parts, and are wanted without departing from such as appended right
In the case of the spirit and scope of the invention for asking restriction, various modifications, variation and deformation are understood that from the description of front.The present invention
Do not limited by the shown sequence of step because some steps can in a different order and/or with other steps simultaneously into
Row.Therefore, the present invention is not limited to disclosed（It is one or more）Specific embodiment, but will will include to fall and be wanted in appended right
All embodiments in the range of asking.
Claims (17)
1. a kind of intraocular implant, which is characterized in that the intraocular implant includes the first component and second component, and described
The circumferential edge of one component and the circumferential edge of the second component are connected with each other in the first component and second described
Pouch is formed between part, the pouch is used to accommodate intraocular lens, wherein：
The first component includes the first disk, and first disk has centrally located elliptical aperture；And
The second component includes the second disk, and second disk has centrally located circular hole.
2. intraocular implant according to claim 1, which is characterized in that the long axis of the elliptical aperture in the horizontal direction, institute
The short axle of elliptical aperture is stated in vertical direction, the long axis of the elliptical aperture and short axle are from the front surface of the first component to described
The rear surface of one component, which gradually tapers up, to become smaller.
3. intraocular implant according to claim 2, which is characterized in that a diameter of 9.0-13.0mm of the first component
And thickness is 0.2-0.5mm, it is preferable that a diameter of 10.0-12.0mm and thickness of the first component are 0.3-
0.4mm。
4. intraocular implant according to claim 2, which is characterized in that the length of the long axis of the elliptical aperture is 7.0-
The length of 9.0mm, the short axle of the elliptical aperture are 4.5-6.5mm, it is preferable that the length of the long axis of the elliptical aperture is 7.5-
The length of 8.5mm, the short axle of the elliptical aperture are 5.0-6.0mm.
5. intraocular implant according to claim 1, which is characterized in that the second component of the intraocular implant is in circumferential direction
Edge includes curved surface and is connect with the first component via the curved surface.
6. intraocular implant according to claim 5, which is characterized in that a diameter of 9.0-13.0mm of the second component
And thickness is 0.3-0.6mm, it is preferable that a diameter of 10.0-12.0mm and thickness of the second component are 0.4-
0.5mm。
7. intraocular implant according to claim 5, which is characterized in that a diameter of 2.5- of the circular hole of the second component
5.0mm, preferably 3.2-4.2mm.
8. intraocular implant according to claim 5, which is characterized in that the second component includes one or more tapers
Hole, one or more of bellmouths are 30-60 degree, preferably 31-45 degree with the angle that the second component is formed.
9. intraocular implant according to claim 1, which is characterized in that the internal diameter of the pouch is 8.4-12.4mm, excellent
It is selected as 9.0-11.4mm, and the height of the pouch is 0.3-0.7mm, preferably 0.4-0.5mm.
10. intraocular implant according to claim 1, which is characterized in that the front surface of the first component to described
The overall thickness of the rear surface of two components is 0.8-2.0mm, preferably 1.0-2.0mm, more preferably 1.2-1.5mm.
11. intraocular implant according to claim 1, which is characterized in that when the intraocular implant is implanted intraocular,
The front surface elongation film 2.4-3.7mm of the first component.
12. intraocular implant according to claim 1, which is characterized in that the intraocular implant is added using 3D printing, machine
The mode of cutting or die casting is process.
13. intraocular implant according to claim 1, which is characterized in that the intraocular implant is planted by can be used for intraocular
The flexible high molecular material or biomaterial entered is made.
14. intraocular implant according to claim 1, which is characterized in that the first component and/or the second component
It is single layer structure, the first component and/or the second component are solid colors or have a multiple color.
15. intraocular implant according to claim 1, which is characterized in that the first component and/or the second component
It is multi-layer compound structure, each layer of the multi-layer compound structure of the first component and/or the second component is solid color
Or have multiple color.
16. intraocular implant according to claim 15, which is characterized in that the first component is three-layer composite structure,
It includes first layer, the second layer and third layer, wherein the first layer be white, the second layer be located at the first layer with
Between the third layer and it is red, brown, Lan Sanse colored structures, the third layer is white.
17. intraocular implant according to claim 15, which is characterized in that the first component is with multiple color
Single layer structure, and the second component is three-layer composite structure comprising first layer, the second layer and third layer, wherein described
First layer is white, and the second layer is between the first layer and the third layer and is multiple color, the third
Layer is white.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710131169.4A CN108567508A (en) | 2017-03-07 | 2017-03-07 | Intraocular implant |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710131169.4A CN108567508A (en) | 2017-03-07 | 2017-03-07 | Intraocular implant |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN108567508A true CN108567508A (en) | 2018-09-25 |
Family
ID=63577210
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201710131169.4A Pending CN108567508A (en) | 2017-03-07 | 2017-03-07 | Intraocular implant |
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| Country | Link |
|---|---|
| CN (1) | CN108567508A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111973315A (en) * | 2020-09-02 | 2020-11-24 | 岳阳爱尔眼科医院有限公司 | Colored artificial lens |
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Address after: 102200 No. 9 Xingchang Road, Changping District Science and Technology Park, Beijing Applicant after: Abbott (Beijing) Medical Technology Co., Ltd. Address before: 102200, Changping District Beijing science and Technology Park, super Road, No. 37, building 1, 6 North Zone Applicant before: Eponode (Beijing) Medical Technology Co., Ltd. |