CN108562928A - Detector and Positron emission tomography equipment for Positron emission tomography equipment - Google Patents

Detector and Positron emission tomography equipment for Positron emission tomography equipment Download PDF

Info

Publication number
CN108562928A
CN108562928A CN201711361772.8A CN201711361772A CN108562928A CN 108562928 A CN108562928 A CN 108562928A CN 201711361772 A CN201711361772 A CN 201711361772A CN 108562928 A CN108562928 A CN 108562928A
Authority
CN
China
Prior art keywords
scintillation crystal
sheet
detector
crystal module
module
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CN201711361772.8A
Other languages
Chinese (zh)
Other versions
CN108562928B (en
Inventor
张熙
谢思维
杨静梧
赵指向
黄秋
彭旗宇
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Guangdong Shadow Digital Medical Science And Technology Co Ltd
Sino Science And Technology (shenzhen) Co Ltd
Original Assignee
Guangdong Shadow Digital Medical Science And Technology Co Ltd
Sino Science And Technology (shenzhen) Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Guangdong Shadow Digital Medical Science And Technology Co Ltd, Sino Science And Technology (shenzhen) Co Ltd filed Critical Guangdong Shadow Digital Medical Science And Technology Co Ltd
Priority to CN201711361772.8A priority Critical patent/CN108562928B/en
Publication of CN108562928A publication Critical patent/CN108562928A/en
Priority to PCT/CN2018/119268 priority patent/WO2019120078A1/en
Application granted granted Critical
Publication of CN108562928B publication Critical patent/CN108562928B/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01TMEASUREMENT OF NUCLEAR OR X-RADIATION
    • G01T1/00Measuring X-radiation, gamma radiation, corpuscular radiation, or cosmic radiation
    • G01T1/29Measurement performed on radiation beams, e.g. position or section of the beam; Measurement of spatial distribution of radiation
    • G01T1/2914Measurement of spatial distribution of radiation
    • G01T1/2985In depth localisation, e.g. using positron emitters; Tomographic imaging (longitudinal and transverse section imaging; apparatus for radiation diagnosis sequentially in different planes, steroscopic radiation diagnosis)
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01TMEASUREMENT OF NUCLEAR OR X-RADIATION
    • G01T1/00Measuring X-radiation, gamma radiation, corpuscular radiation, or cosmic radiation
    • G01T1/16Measuring radiation intensity
    • G01T1/161Applications in the field of nuclear medicine, e.g. in vivo counting
    • G01T1/164Scintigraphy

Landscapes

  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • High Energy & Nuclear Physics (AREA)
  • Molecular Biology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medical Informatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Optics & Photonics (AREA)
  • Measurement Of Radiation (AREA)
  • Nuclear Medicine (AREA)

Abstract

The present invention provides a kind of detector and the transmitting imaging device with the detector.Detector includes scintillation crystal module and photosensor arrays, scintillation crystal module includes multiple sheet scintillation crystal units, each sheet scintillation crystal unit has through-hole, multiple sheet scintillation crystal units are axially accumulated to form the scintillation crystal module, accumulation, which is formed by the scintillation crystal module, has inner wall, outer wall and through hole, and the through hole is for accommodating object to be imaged.Photosensor arrays are coupling in the inner wall of the scintillation crystal module or/and the outer wall of the scintillation crystal module, it reacts generated optical photon for detecting gamma photons and the scintillation crystal module, wherein, the gamma photons in the esoteric positron annihilation effect of object to be imaged by generating.The detector difficulty of processing is low, and assembling is simple, and has higher DOI decoding precision and position decoding ability.

Description

Detector and Positron emission tomography equipment for Positron emission tomography equipment
Technical field
The present invention relates to Positron emission tomography fields, and in particular, to a kind of for Positron emission tomography equipment Detector and Positron emission tomography equipment.
Background technology
Medical positron emission tomography (Positron Emission Tomography, PET) is international first Into the representative products of medical instrument, it is the skill that human body or animal body internal structure are shown using radioactive element tracing method Art, be clinically widely used in the early diagnosis of tumour, cardiovascular and cerebrovascular disease and neurodegenerative disease, therapeutic scheme is formulated, Outcome prediction and medicine curative effect evaluation etc..
Traditional medical positron emission tomography, detector system are generally led to by multiple square detector modules Mechanical structure connection is crossed, columnar envelope structure is formed, for intercepting the gammaphoton for receiving radioactive substance release.Specifically Ground, square detector module are coupled to form by scintillation crystal (scintillation crystal array), photoelectric sensor, some designs can will also be read Go out circuit to be placed in module;Multiple square detectors are fixed by complicated mechanical structure, are arranged along cylindrical surface or spherical surface, Form gammaphoton detection layers.
Since the assembling of detector is spliced, causes traditional Positron emission tomography equipment to mostly use discrete crystal greatly and set Meter, the design of discrete crystal frequently can lead to following Railway Project:
(1) crystal pro cessing difficulty is big:Traditional square crystal design often uses the scintillation crystal unit of small size, to improve Systemic resolution, but this method requires strictly crystal pro cessing, it is expensive;
(2) edge effect:It is likely to occur edge effect in discrete crystal assembling design so that the Photon confidence detected Breath cannot correctly reflect light distribution, cause decoding precision low, imaging device spatial resolution is low;
(3) existence position error is assembled:The detector module being bolted together easy tos produce position error, so as to cause symbol There is deviation in the detection of conjunction event, and then influences the spatial resolution of imaging device;
(4) detector gap:Detector gap includes crystal assembly clearance:Discrete crystal is will produce when splicing between larger assembling Gap, detecting module gap:Complete detection faces can not be formed when rectangular detecting module is along annular arrangement, both can cause to detect The appearance in gap, to reduce system sensitivity.
Traditional Positron emission tomography equipment also has the continuous crystal design using sheet, the continuous crystal of sheet to pass through Optics connects, to form semicontinuous crystal, is a kind of long-standing solution.This method reduces pair to a certain extent The requirement of crystal pro cessing technology difficulty, but still can not solve the problems, such as that edge effect is brought.
Therefore, it is necessary to propose a kind of detector for Positron emission tomography equipment and including the detector Positron emission tomography equipment improves system sensitivity and spatial resolution to reduce Machine Design difficulty, improves decoding precision Further increase systemic resolution.
Invention content
According to an aspect of the present invention, a kind of detector for Positron emission tomography equipment, including flicker are provided Crystal module and photosensor arrays, scintillation crystal module include multiple sheet scintillation crystal units, each sheet Scintillation crystal unit has through-hole, and axially accumulation is to form the scintillation crystal module for multiple sheet scintillation crystal units, accumulation Being formed by the scintillation crystal module has inner wall, outer wall and through hole, and the through hole is for accommodating object to be imaged.Light Electric transducer array is coupling in the inner wall of the scintillation crystal module or/and the outer wall of the scintillation crystal module, for detecting Gamma photons and the scintillation crystal module react generated optical photon, wherein the gamma photons pass through in institute The esoteric positron annihilation effect of object to be imaged is stated to generate.
Preferably, it is connected by reflective layer between the sheet scintillation crystal unit described in adjacent two.
Preferably, optical transmission window is offered on the reflective layer.
Preferably, the optical transmission window on each reflective layer is one, be arranged in the inside of the reflective layer or It is external;Or, the optical transmission window on each reflective layer is two, it is separately positioned on the inside of the reflective layer and outer Portion;Or, the optical transmission window on each reflective layer is multiple, multiple optical transmission windows are with from inside to outside or from outside to inside Arrangement mode is arranged at intervals on the reflective layer.
Preferably, the scintillation crystal module is in integrally polygon prism shape or cylindric.
Preferably, the through-hole is round or polygon.
Preferably, the sheet scintillation crystal unit is formed by connecting by multiple scintillation crystals.
Preferably, the scintillation crystal module includes internal layer scintillation crystal module and outer layer scintillation crystal module, it is described in Layer scintillation crystal module includes multiple first sheet scintillation crystal units, and each first sheet scintillation crystal unit has the One through-hole, multiple first sheet scintillation crystal units are axially accumulated to form the internal layer scintillation crystal module;The outer layer dodges Bright crystal module includes multiple second sheet scintillation crystal units, and each second sheet scintillation crystal unit has second to lead to Hole, multiple second sheet scintillation crystal units are axially accumulated to form the outer layer scintillation crystal module;First sheet is dodged Bright crystal unit can be accommodated in second through-hole, and first sheet flicker of the internal layer scintillation crystal module is brilliant The second sheet scintillation crystal unit Heterogeneous Permutation of the relatively described outer layer scintillation crystal module of body unit.
Preferably, the photosensor arrays include multiple photoelectric sensors, and one in the multiple photoelectric sensor There are one the sheet scintillation crystal units for a coupling respectively.
Preferably, the photosensor arrays include multiple photoelectric sensors, in the multiple photoelectric sensor extremely Few one is coupled with multiple sheet scintillation crystal units respectively.
Preferably, the photosensor arrays include m × n photoelectric sensor, and wherein m, n are positive integer, and m rows On photoelectric sensor and m+1 rows on photoelectric sensor Heterogeneous Permutation.
Preferably, the photosensor arrays include m × n photoelectric sensor, and wherein m, n are positive integer, and n-th arranges On photoelectric sensor and (n+1)th row on photoelectric sensor Heterogeneous Permutation.
According to another aspect of the present invention, a kind of Positron emission tomography equipment is also provided, the positron emission at As equipment includes reading circuit module, data processing module and such as above-mentioned detector, the reading circuit module and the light Electric transducer array connects, the electric signal for receiving the photosensor arrays output, and exports the energy of gamma photons Information and temporal information, the electric signal are the optical signals of the optical photon detected to it by the photosensor arrays It is converted and is obtained.The data processing module is connect with the reading circuit module, for the energy information and The temporal information carries out data processing and image reconstruction, to obtain the scan image of object to be imaged.
Due to accumulating to form scintillation crystal module using the sheet scintillation crystal unit with through-hole, detection provided by the invention Device mainly has following several big advantages:
1, crystal pro cessing difficulty reduces, and system cost declines;
2, continuously or semi-continuously crystal structure, can reduce the solution code error that edge effect is brought;
3, crystal assembling is simple, can greatly reduce multimode positioning, the site error that splicing tape comes;
4, minimum or even nothing gaps between crystals, fully improve system sensitivity.
A series of concept of reduced forms is introduced in invention content, this will in the detailed description section further It is described in detail.This part of the disclosure be not meant to attempt to limit technical solution claimed key feature and Essential features do not mean that the protection domain for attempting to determine technical solution claimed more.
Below in conjunction with attached drawing, the advantages of the present invention will be described in detail and feature.
Description of the drawings
The following drawings of the present invention is used to understand the present invention in this as the part of the present invention.Shown in the drawings of this hair Bright embodiment and its description, principle used to explain the present invention.In the accompanying drawings,
Fig. 1 is the structure chart according to the detector for Positron emission tomography equipment of one embodiment of the invention;
Fig. 2 a- Fig. 2 d are that schematic diagram is arranged according to the optical transmission window of one embodiment of the invention;
Fig. 3 is the decoded schematic diagrames of DOI according to the detector of one embodiment of the invention;
Fig. 4 is the windowing DOI decoding principle figures according to one embodiment of the invention;
Fig. 5 a- Fig. 5 d are the structure chart according to the sheet scintillation crystal unit of the embodiment of the present invention;
Fig. 6 is the structure chart according to the scintillation crystal module of another embodiment of the invention;
Fig. 7 a- Fig. 7 d are the structure chart according to the sheet scintillation crystal unit of another embodiment of the invention;
Fig. 8 is the structure chart according to the detector for Positron emission tomography equipment of another embodiment of the invention;
Fig. 9 a- Fig. 9 c are to be illustrated according to a kind of coupled modes of the photosensor arrays of the detector of the embodiment of the present invention Figure;
Figure 10 a- Figure 10 d are to flicker crystalline substance according to photoelectric sensor on the same light reading face of the embodiment of the present invention and sheet The coupled modes schematic diagram of body unit;
Figure 11 is the schematic diagram according to the Positron emission tomography equipment of one embodiment of the invention.
Wherein, reference numeral is
10-crystal modules
11-sheet scintillation crystal units
111-through-holes
101-scintillation crystals
102-connectors
105-through holes
110-internal layer scintillation crystal modules
1101-the first sheet scintillation crystal unit
1111-through-holes
120-outer layer scintillation crystal modules
1201-the second sheet scintillation crystal unit
1211-through-holes
20,20 '-photosensor arrays
21-photoelectric sensors
30-light guides
40-reflective layers
40 '-reflecting pieces
50-optical transmission windows
100-detector modules
200-reading circuit modules
300-data processing modules
Specific implementation mode
In the following description, a large amount of details is provided so as to thoroughly understand the present invention.However, this field skill Art personnel will be seen that, only relate to presently preferred embodiments of the present invention described below, and the present invention may not need one or more in this way Details and be carried out.In addition, in order to avoid obscuring with the present invention, not for some technical characteristics well known in the art It is described.
The present invention provides a kind of detector for Positron emission tomography equipment comprising scintillation crystal module and photoelectricity Sensor array.As shown in Figure 1, scintillation crystal module 10 includes multiple sheet scintillation crystal units 11, each sheet flicker is brilliant There is body unit 11 through-hole 111, the axial accumulation of multiple sheet scintillation crystal units 11 to accumulate institute to form scintillation crystal module 10 The scintillation crystal module of formation has inner wall 106, outer wall 108 and through hole 105.Through hole 105 is used to accommodate object to be imaged, The center line of through hole 105 is overlapped with the center line of through-hole 111.Photosensor arrays 20 are coupling in the outer of scintillation crystal module Wall 108, the face where outer wall 108 be light read face (will subsequently refer to the inner wall 106 for being coupling in scintillation crystal module, and The embodiment of photosensor arrays is all coupled on the inner wall 106 and outer wall 108 of scintillation crystal module), for detecting gamma light Son reacts generated optical photon with scintillation crystal module 10, wherein the gamma photons pass through in object to be imaged Esoteric positron annihilation effect generates.
From structure description above as can be seen that the detector of the Positron emission tomography equipment of the present invention is by carrying through-hole 111 sheet scintillation crystal unit 11 is assembled into scintillation crystal module 10, and sheet scintillation crystal unit 11 each other can be by reflective 40 connection (that is, being connected by reflective layer 40 between adjacent two sheets scintillation crystal unit) of layer, 11 axis of sheet scintillation crystal unit To accumulation to meet the requirement of axial visual field length.There are many kinds of the materials of reflective layer 40, including diffuse-reflective material:BaSO4, plating Film etc., specular reflective material:ESR, plated film etc.;Unrestrained transmitting, mirror-reflection mixing material:Teflon adhesive tape, titania coating etc., By adjusting the thickness of reflective layer 40, adjacent 11 light transmissions of sheet scintillation crystal unit can be allowed, to realize position decoding.
Can be that multiple sheet scintillation crystal units 11 are first assembled into small scintillation crystal module during actual assembled, Again scintillation crystal module 10 is axially piled by multiple small scintillation crystal modules.
Illustratively, it can be connected by light guide 30 between photosensor arrays 20 and scintillation crystal module 10, to So that photoelectric sensor is detected the optical signal of non-coupled crystal, realizes position decoding.In unshowned embodiment, scintillation crystal Module 10 and photosensor arrays 20 can be straight for example, by the couplant of optical glue or by modes such as Air Couplings It connects and is coupled.
Illustratively, can offer optical transmission window 50 on reflective layer 40, optical transmission window 50 can be used simultaneously reflectorized material, Air or optical glue are achieved.
In conjunction with refering to Fig. 2 a to Fig. 2 d, there are many set-up modes of optical transmission window 50, e.g., the light transmission on each reflective layer 40 Window 50 is one, is arranged in the inside (such as Fig. 2 a) of reflective layer 40, for the outside that inside herein is chatted afterwards relatively, closer to The inner wall 106 of scintillation crystal module;Or, the optical transmission window 50 on each reflective layer 40 is one, it is arranged in the outer of reflective layer 40 Portion (such as Fig. 2 b), for the inside that outside herein is before chatted relatively, closer to the outer wall 108 of scintillation crystal module;Or, each anti- Optical transmission window 50 on photosphere 40 is two, is separately positioned on inside and outside (such as Fig. 2 c) of reflective layer 40;Or, each reflective Optical transmission window 50 on layer 40 is multiple, and multiple optical transmission windows 50 are arranged with arrangement mode interval from inside to outside or from outside to inside On reflective layer 50 (such as Fig. 2 d).
In conjunction with refering to Fig. 3, for the crystal module that sheet scintillation crystal unit 11 forms, with Fig. 1 structures and optical transmission window For, propose following location decodingmethod:
1, short transverse decodes:By photosensor arrays 20, the light distribution of short transverse is measured, realizes short transverse Centroid algorithm, neural network algorithm or other algorithms can be selected in decoding, algorithm;
2, angle direction decodes:By photosensor arrays 20, the light distribution in measurement angle direction realizes angle direction Centroid algorithm, neural network algorithm or other algorithms can be selected in decoding, algorithm;
3, DOI (radial direction) is decoded:By photosensor arrays 20, measurement can be used for the decoded light in the directions DOI point Neural network algorithm or other algorithms can be selected in cloth, algorithm;As shown in the figure of the upper left corners Fig. 3,21 both-end of photoelectric sensor is read, and is read The half-peak breadth and peak value for taking energy signal realize that DOI is decoded using neural network algorithm.
Again as shown in figure 4, the axial accumulation of multiple sheet scintillation crystal units 11 is to form scintillation crystal module, photoelectric sensing Device 21 is coupling in the outer wall of scintillation crystal module, and the optical transmission window 50 on each reflective layer 40 is one, is arranged in reflective layer 40 Inside, that is, using internal single window method, the response location of different depth can obtain big difference from single-ended photoelectric sensor 21 Light distribution, to realize that DOI is decoded.
Illustratively, as shown in Figure 5 a, sheet scintillation crystal unit 11 is circle, and through-hole 111 is also circle, multiple sheets The scintillation crystal module 10 that scintillation crystal unit 11 is axially accumulated and formed is cylindric (such as Fig. 1).
Illustratively, as shown in Figure 5 b, sheet scintillation crystal unit 11 is circle, and through-hole 111 is polygon, multiple sheets The scintillation crystal module 10 that scintillation crystal unit 11 is axially accumulated and formed is generally cylindric.
Illustratively, as shown in Figure 5 c, sheet scintillation crystal unit 11 is polygon, and through-hole 111 is round, multiple The generally polygon prism shape of scintillation crystal module 10 of the axial accumulation of shape scintillation crystal unit 11 and formation.
Illustratively, as fig 5d, sheet scintillation crystal unit 11 is polygon, and through-hole 111 is also polygon, more The generally polygon prism shape of scintillation crystal module 10 of the axial accumulation of a sheet scintillation crystal unit 11 and formation.It should be noted that in piece Shape scintillation crystal unit 11 is polygon, in the case that through-hole 111 is also polygonal through hole, sheet scintillation crystal unit 11 Number of edges and the number of edges of through-hole may be the same or different.
Although in Fig. 5 c and Fig. 5 d, sheet scintillation crystal unit 11 is shown as hexagonal structure, axially accumulates and is formed The generally hexa-prism structure of scintillation crystal module 10, it is noted that the number of edges of sheet scintillation crystal unit 11 can be with It is any suitable number, the present invention limits not to this.For example, sheet scintillation crystal unit 11 can be triangle, four Side shape, pentagon etc., accordingly, scintillation crystal module can be triangular prism shape, quadrangular shape, pentagonal prism made of axial accumulation Shape, etc..Similarly, through-hole can be tetragonal through hole, hexagon through-hole, 20 tetragonal through hole, etc..
As shown in fig. 6, for according to the structure chart of the scintillation crystal module of another embodiment of the invention.In the present embodiment, Sheet scintillation crystal unit 11 is formed by connecting by multiple scintillation crystals 101, illustratively, is fanned between cricoid scintillation crystal 101 Annular slice scintillation crystal unit 11 is connected by connector 102, connector can be optical glue, and the flicker of two annular slices is brilliant It can be connected by reflecting piece 40 ' between body unit 11.Optical glue plays connection function, while making the cricoid scintillation crystal of fan 101 Between light can mutually transmit, form semicontinuous crystal, connector 102 includes but not limited to optical glue.
Illustratively, as shown in Figure 7a, scintillation crystal 101 is that fan is cyclic annular, is fanned between cricoid scintillation crystal 101 by connecting Body 102 connects into annular slice scintillation crystal unit 11, and through-hole 111 is circle, multiple 11 axis of annular slice scintillation crystal unit To accumulation, the scintillation crystal module 10 that is formed is cylindric (such as Fig. 6).
Illustratively, as shown in Figure 7b, the outer rim of scintillation crystal 101 is arc, and inner edge is linear, every two scintillation crystal Slabbing scintillation crystal unit 11 is connected by connector 102 between 101, sheet scintillation crystal unit 11 is generally round, through-hole 111 be polygon, and the scintillation crystal module 10 that multiple sheet scintillation crystal units 11 are axially accumulated and formed is generally cylindric.
Illustratively, as shown in Figure 7 c, the inner edge of scintillation crystal 101 is linear, and outer rim is linear, and every two flicker is brilliant Slabbing scintillation crystal unit 11 is connected by connector 102 between body 101, the generally polygon of sheet scintillation crystal unit 11, Through-hole 111 is circle, and multiple sheet scintillation crystal units 11 are axially accumulated and the generally more ribs of scintillation crystal module 10 of formation Column.
Illustratively, as shown in figure 7d, the inner edge of scintillation crystal 101 is linear, and outer rim is linearity, and every two flicker is brilliant Slabbing scintillation crystal unit 11 is connected by connector 102 between body 101, the generally polygon of sheet scintillation crystal unit 11, Through-hole 111 is also polygon, and the axial scintillation crystal module 10 accumulated and formed of multiple sheet scintillation crystal units 11 is generally Polygon prism shape.It should be noted that being piece in the case that polygon through-hole 111 is also polygonal through hole in sheet scintillation crystal unit 11 The number of edges of shape scintillation crystal unit 11 and the number of edges of through-hole may be the same or different.
Although in Fig. 7 c and Fig. 7 d, sheet scintillation crystal unit 11 is shown as hexagonal structure, axially accumulates and is formed The generally hexa-prism structure of scintillation crystal module 10, it is noted that the number of edges of sheet scintillation crystal unit 11 can be with It is any suitable number, the present invention limits not to this.For example, sheet scintillation crystal unit 11 can be triangle, four Side shape, pentagon etc., accordingly, scintillation crystal module can be triangular prism shape, quadrangular shape, pentagonal prism made of axial accumulation Shape, etc..Similarly, through-hole can be tetragonal through hole, hexagon through-hole, 20 tetragonal through hole, etc..
As shown in figure 8, for according to the structure chart of the detector of another embodiment of the invention.In the present embodiment, flicker is brilliant Module 10 includes internal layer scintillation crystal module 110 and outer layer scintillation crystal module 120, and internal layer scintillation crystal module 110 includes Multiple first sheet scintillation crystal units 1101, every 1 first sheet scintillation crystal unit 1101 has first through hole 1111, more The axial accumulation of a first sheet scintillation crystal unit 1101 is to form internal layer scintillation crystal module 110;Outer layer scintillation crystal module 120 include multiple second sheet scintillation crystal units 1201, and every 1 second sheet scintillation crystal unit 1201 has second to lead to Hole 1211, the axial accumulation of multiple second sheet scintillation crystal units 1211 is to form outer layer scintillation crystal module 120;First sheet Scintillation crystal unit 1101 can be accommodated in the second through-hole 1211, and the first sheet flicker of internal layer scintillation crystal module 110 1201 Heterogeneous Permutation of the second sheet scintillation crystal unit of 1101 opposed outer layer scintillation crystal module 120 of crystal unit.This implementation The detector of example introduces double-deck scintillation crystal module of dislocation, and the detector of the structure can carry out reaction deeply by decoded positions Degree judges.
The photosensor arrays component part important as detector, size, detection efficient, position distribution etc. because Element will directly affect position decoding precision, and determine the quality that later image is rebuild.And the performance of photoelectric sensor itself is by giving birth to Production. art process determines.Interior coupled modes as illustrated in fig. 9 may be used in the location arrangements of photosensor arrays, that is, photoelectricity Sensor array 20 is coupled to the inner wall 106 of scintillation crystal module 10, and the face where inner wall 106 is the light of scintillation crystal module 10 Reading face.
The location arrangements of photosensor arrays can also use outer coupled modes as shown in figure 9b, that is, photoelectric sensing Device array 20 is coupled to the outer wall 108 of scintillation crystal module 10, and the face where outer wall 108 is that the light of scintillation crystal module 10 is read Face.
The location arrangements of photosensor arrays can also use inside and outside double coupled modes as is shown in fig. 9 c, scintillation crystal It is all coupled with photoelectric sensor device array on the inner wall 106 and outer wall 108 of module 10, that is, photosensor arrays 20 ' are coupled to The inner wall 106 of scintillation crystal module 10, photosensor arrays 20 are coupled to the outer wall 108 of scintillation crystal module 10, inner wall 106 The face at place, the face at 108 place of outer wall read face for the light of scintillation crystal module 10 simultaneously.
On same light reading face, also there are many modes for the coupling between photoelectric sensor and sheet scintillation crystal unit. As shown in Figure 10 a, one-to-one coupled modes are used, specifically, photosensor arrays 20 include multiple photoelectric sensors 21, a photoelectric sensor 21 in multiple photoelectric sensors only couples that there are one sheet scintillation crystal unit 11, two sheets It is connected by reflective layer 40 between scintillation crystal unit 11.As shown in fig. lob, one-to-many coupled modes are used, specifically, Photosensor arrays 20 include multiple photoelectric sensors 21,21 coupling of at least one of multiple photoelectric sensors photoelectric sensor Conjunction has multiple sheet scintillation crystal units 11.As shown in figure l0c, dislocation coupled modes, specifically, photoelectric sensor are used Array 20 includes m × n photoelectric sensor 21, and wherein m, n are positive integer, and the photoelectric sensor 21 and (n+1)th on the n-th row arranges On 21 Heterogeneous Permutation of photoelectric sensor.As shown in fig. 10d, dislocation coupled modes are used, specifically, photoelectric sensor battle array Row 20 include m × n photoelectric sensor 21, and wherein m, n are positive integer, and the photoelectric sensor 21 on m rows and m+1 rows On 21 Heterogeneous Permutation of photoelectric sensor.
The detector of the present invention is single due to accumulating to form scintillation crystal module using the sheet scintillation crystal unit with through-hole For the decoding angle of position, there is following advantage:
1, angle direction resolution ratio:The continuously or semi-continuously boundless edge effect of crystal has very big in angle direction decoding Advantage;
2, axial resolution:Similar with conventional crystal assembling mode, axial resolution depends on the thickness of assembling crystal wafer;
3, DOI resolution ratio:Using inside and outside double coupled methods or window technique, high DOI can be obtained by comparing light distribution Resolution ratio;
4, many-one coupling can reduce system cost, and dislocation coupling can obtain special position decoding effect.
According to a further aspect of the invention, a kind of Positron emission tomography equipment is provided.As shown in figure 11, positron emission at As equipment includes that reading circuit module 200, data processing module 300 and above-mentioned detector (are shown as detector mould in Figure 11 Block 100), reading circuit module 200 is connect with the photosensor arrays in detector, defeated for receiving photosensor arrays The electric signal gone out, and the energy information and temporal information of gamma photons are exported, the electric signal is to pass through photosensor arrays The optical signal of the optical photon detected to it is converted and is obtained.Data processing module 300 and reading circuit module 200 Connection, for carrying out data processing and image reconstruction to the energy information and the temporal information, to obtain object to be imaged Scan image.Reading circuit module 200 and data processing module 300 may be used any suitable hardware, software and/or consolidate Part is realized.Illustratively, field programmable gate array (FPGA), digital signal processor may be used in data processing module 300 (DSP), the realizations such as Complex Programmable Logic Devices (CPLD), micro-control unit (MCU) or central processing unit (CPU).
The present invention is illustrated by above-described embodiment, but it is to be understood that, above-described embodiment is only intended to The purpose of citing and explanation, and be not intended to limit the invention within the scope of described embodiment.In addition people in the art It is understood that the invention is not limited in above-described embodiment, introduction according to the present invention can also be made more kinds of member Variants and modifications, these variants and modifications are all fallen within scope of the present invention.Protection scope of the present invention by The appended claims and its equivalent scope are defined.

Claims (13)

1. a kind of detector for Positron emission tomography equipment, which is characterized in that including:
Scintillation crystal module, including multiple sheet scintillation crystal units, each sheet scintillation crystal unit has through-hole, more Axially to form the scintillation crystal module, accumulation is formed by the scintillation crystal module to a sheet scintillation crystal unit for accumulation With inner wall, outer wall and through hole, the through hole is for accommodating object to be imaged;And
Photosensor arrays are coupling in the inner wall of the scintillation crystal module or/and the outer wall of the scintillation crystal module, use It reacts generated optical photon in detection gamma photons and the scintillation crystal module, wherein the gamma photons are logical It crosses and is generated in the esoteric positron annihilation effect of object to be imaged.
2. detector as described in claim 1, which is characterized in that pass through between the sheet scintillation crystal unit described in adjacent two Reflective layer connects.
3. detector as claimed in claim 2, which is characterized in that offer optical transmission window on the reflective layer.
4. detector as claimed in claim 3, which is characterized in that the optical transmission window on each reflective layer is one It is a, it is arranged inside or outside the reflective layer;Or, the optical transmission window on each reflective layer is two, respectively It is arranged in the inside and outside of the reflective layer;Or, the optical transmission window on each reflective layer is multiple, multiple light transmissions Window is arranged at intervals on arrangement mode from inside to outside or from outside to inside on the reflective layer.
5. detector as described in claim 1, which is characterized in that the scintillation crystal module is in integrally polygon prism shape or cylinder Shape.
6. detector as described in claim 1, which is characterized in that the through-hole is round or polygon.
7. detector as described in claim 1, which is characterized in that the sheet scintillation crystal unit is connected by multiple scintillation crystals It connects.
8. the detector as described in any one of claim 1-7, which is characterized in that the scintillation crystal module includes internal layer Scintillation crystal module and outer layer scintillation crystal module, the internal layer scintillation crystal module include multiple first sheet scintillation crystal lists There is first through hole, multiple first sheet scintillation crystal units axially to accumulate for member, each first sheet scintillation crystal unit To form the internal layer scintillation crystal module;The outer layer scintillation crystal module includes multiple second sheet scintillation crystal units, There is each second sheet scintillation crystal unit the second through-hole, multiple second sheet scintillation crystal units axially to accumulate with shape At the outer layer scintillation crystal module;The first sheet scintillation crystal unit can be accommodated in second through-hole, and institute State described the of the relatively described outer layer scintillation crystal module of the first sheet scintillation crystal unit of internal layer scintillation crystal module Two sheet scintillation crystal unit Heterogeneous Permutations.
9. the detector as described in any one of claim 1-7, which is characterized in that the photosensor arrays include more A photoelectric sensor, there are one the sheet scintillation crystal units for coupling respectively by one in the multiple photoelectric sensor.
10. the detector as described in any one of claim 1-7, which is characterized in that the photosensor arrays include Multiple photoelectric sensors, at least one of the multiple photoelectric sensor are coupled with multiple sheet scintillation crystal lists respectively Member.
11. the detector as described in any one of claim 1-7, which is characterized in that the photosensor arrays include m × n photoelectric sensor, wherein m, n are positive integer, and the photoelectric sensor on the photoelectric sensor and m+1 rows on m rows Heterogeneous Permutation.
12. the detector as described in any one of claim 1-7, which is characterized in that the photosensor arrays include m × n photoelectric sensor, wherein m, n are positive integer, and the photoelectric sensor on the photoelectric sensor and the (n+1)th row on the n-th row Heterogeneous Permutation.
13. a kind of Positron emission tomography equipment, which is characterized in that the Positron emission tomography equipment includes reading circuit mould Block, data processing module and the detector as described in any one of claim 1-12, wherein
The reading circuit module is connect with the photosensor arrays, for receiving the photosensor arrays output Electric signal, and the energy information and temporal information of gamma photons are exported, the electric signal is by the photosensor arrays The optical signal of the optical photon detected to it is converted and is obtained;
The data processing module is connect with the reading circuit module, for the energy information and the temporal information into Row data processing and image reconstruction, to obtain the scan image of object to be imaged.
CN201711361772.8A 2017-12-18 2017-12-18 Detector for positron emission imaging apparatus and positron emission imaging apparatus Active CN108562928B (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
CN201711361772.8A CN108562928B (en) 2017-12-18 2017-12-18 Detector for positron emission imaging apparatus and positron emission imaging apparatus
PCT/CN2018/119268 WO2019120078A1 (en) 2017-12-18 2018-12-05 Detector for positron emission tomography device, and positron emission tomography device

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201711361772.8A CN108562928B (en) 2017-12-18 2017-12-18 Detector for positron emission imaging apparatus and positron emission imaging apparatus

Publications (2)

Publication Number Publication Date
CN108562928A true CN108562928A (en) 2018-09-21
CN108562928B CN108562928B (en) 2022-01-21

Family

ID=63529478

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201711361772.8A Active CN108562928B (en) 2017-12-18 2017-12-18 Detector for positron emission imaging apparatus and positron emission imaging apparatus

Country Status (2)

Country Link
CN (1) CN108562928B (en)
WO (1) WO2019120078A1 (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109846504A (en) * 2018-05-07 2019-06-07 山东麦德盈华科技有限公司 A kind of full angle meets pet detector
WO2019120078A1 (en) * 2017-12-18 2019-06-27 中派科技(深圳)有限责任公司 Detector for positron emission tomography device, and positron emission tomography device

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4755680A (en) * 1984-04-27 1988-07-05 The Curators Of The University Of Missouri Radiation imaging apparatus and methods
EP2360493A1 (en) * 2010-02-15 2011-08-24 Bergen Teknologioverføring AS Detector arrangement for a tomographic imaging apparatus, particularly for a positron emission tomograph
CN105361901A (en) * 2015-12-19 2016-03-02 山西锦地裕成医疗设备有限公司 Method and system for correcting depth effect of positron emission tomography
CN106562799A (en) * 2016-10-19 2017-04-19 武汉中派科技有限责任公司 Detector for positron emission imaging equipment, and positron emission imaging equipment

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2016015061A1 (en) * 2014-07-25 2016-01-28 The Regents Of The University Of California Multiple spatial resolution scintillation detectors
CN106597518A (en) * 2016-12-21 2017-04-26 中国科学院深圳先进技术研究院 PET detector, PET imaging system and PET tester
CN106725574A (en) * 2017-01-17 2017-05-31 孙红岩 A kind of positron emission computerized tomography imaging system bimorph crystal detector
CN107272043B (en) * 2017-06-05 2019-06-04 中派科技(深圳)有限责任公司 Detector and transmitting imaging device with the detector
CN108562928B (en) * 2017-12-18 2022-01-21 中派科技(深圳)有限责任公司 Detector for positron emission imaging apparatus and positron emission imaging apparatus

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4755680A (en) * 1984-04-27 1988-07-05 The Curators Of The University Of Missouri Radiation imaging apparatus and methods
EP2360493A1 (en) * 2010-02-15 2011-08-24 Bergen Teknologioverføring AS Detector arrangement for a tomographic imaging apparatus, particularly for a positron emission tomograph
CN105361901A (en) * 2015-12-19 2016-03-02 山西锦地裕成医疗设备有限公司 Method and system for correcting depth effect of positron emission tomography
CN106562799A (en) * 2016-10-19 2017-04-19 武汉中派科技有限责任公司 Detector for positron emission imaging equipment, and positron emission imaging equipment

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2019120078A1 (en) * 2017-12-18 2019-06-27 中派科技(深圳)有限责任公司 Detector for positron emission tomography device, and positron emission tomography device
CN109846504A (en) * 2018-05-07 2019-06-07 山东麦德盈华科技有限公司 A kind of full angle meets pet detector

Also Published As

Publication number Publication date
WO2019120078A1 (en) 2019-06-27
CN108562928B (en) 2022-01-21

Similar Documents

Publication Publication Date Title
WO2018072721A1 (en) Detector for a positron emission tomography apparatus, and positron emission tomography apparatus
US10466371B2 (en) Apparatus and methods for depth-of-interaction positron tomography detector using dichotomous sensing
WO2018223918A1 (en) Detector and emission imaging device having same
US9372267B2 (en) Apparatus and methods for photosensor quadrant sharing
US8063377B2 (en) Crystal identification for high resolution nuclear imaging
US9529100B2 (en) Positron emission tomography detector and positron emission tomography system using same
CN107710018B (en) The sensitivity correction method and radiation tomographic device of radiation detection device
WO2018223917A1 (en) Detector and emission imaging device having same
CN205826876U (en) Positron emission tomography
CN104285161A (en) SPECT/PET imaging system
CN108957517A (en) Detector and Positron emission tomography equipment for Positron emission tomography equipment
CN108562928A (en) Detector and Positron emission tomography equipment for Positron emission tomography equipment
JP6057207B2 (en) Radiation position detector
CN108132483B (en) Detector for positron emission imaging apparatus and positron emission imaging apparatus
CN108508474A (en) Detector and Positron emission tomography equipment for Positron emission tomography equipment
KR20090057831A (en) Multi-layer scintillator detector and positron emission tomography device therewith
Li et al. The engineering and initial results of a transformable low-cost high-resolution PET camera
US4883966A (en) Pet camera with crystal masking
WO2023179761A1 (en) Scintillation crystal array, detector, medical imaging equipment, and manufacturing method
US20170329021A1 (en) System and method for combining detector signals
CN110007332B (en) Crystal array, detector, medical detection device, and method for manufacturing crystal array
CN209433019U (en) Single-ended reading depth measurement pet detector, PET scan imaging system
CN111938683A (en) Full-digital 4Pi solid angle PET imaging method and system
WO2020063232A1 (en) Pet device, multilayer crystal pet detector, and electronic reading module and method therefor
US11982780B2 (en) Helical PET architecture

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
GR01 Patent grant
GR01 Patent grant