CN1085100C - Hemiparalysis curing instrument by central nervous stimulation - Google Patents

Hemiparalysis curing instrument by central nervous stimulation Download PDF

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Publication number
CN1085100C
CN1085100C CN97116097A CN97116097A CN1085100C CN 1085100 C CN1085100 C CN 1085100C CN 97116097 A CN97116097 A CN 97116097A CN 97116097 A CN97116097 A CN 97116097A CN 1085100 C CN1085100 C CN 1085100C
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pulse
circuit
output
instrument
outfan
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CN1210744A (en
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徐兰筠
许辉
徐军
李捷
宋新光
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ENERGY SOURCE INST HENAN PROV
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ENERGY SOURCE INST HENAN PROV
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Abstract

The present invention relates to an electrotherapeutic device, particularly to an electric stimulation device for examining cerebral cortex, spinal marrow and peripheral nerves and treating the sequelae of hemiparalysis. The electric stimulation device is composed of an electric stimulation apparatus and a detesting device, wherein high-voltage wide impulses are generated by the electric stimulation apparatus; the detesting device is used for inducing signals. The electric stimulation device is provided with a sound display device and a light display device. The electric stimulation device can examine and diagnose the status of nerve centers and peripheral nerves and treat the sequelae of hemiparalysis, can examine the therapeutic effect and can be exerted on the sense organ of a patient by sound-light signals to enable the patient to know the therapeutic effect to boost the cure confidence of the patient.

Description

Maincenter stimulates hemiparalysis curing instrument
The present invention relates to a kind of electrotherapeutic apparatus, especially in order to check cerebral cortex, spinal cord and a kind of electrical stimulation device of nervus motorius and treatment hemiplegia sequela on every side.
Rather active in China in recent years to the research of electrotherapy or physical therapy device, wherein major part be based on the theoretical acupoint stimulation of Chinese medicine meridian to lead the Pingyin sun instrument of disease curing and body-building, the instrument that also has at special disease and the focus determined or position row are executed stimulation therapy, the former is the high stable electrotherapeutic apparatus of 94111293.4 power stepless self-increasings and surge output as application number, the latter such as application number 93119769.4 electrochemical cancer and tumor therapeutic apparatus.Pick up in addition in addition and output to conductor after the information processing and amplifying corresponding to certain biological activity state and carry out disease curing and body-building or obtain the pathology bio information through the acupuncture point, handle the back negative feedback to from the former acupuncture point of body with the instrument (or system) of curing the disease.In comparison, to discovery based on silent (Mertou), research low-resistance, the narrow electric pulse of high pressure stimulate zona rolandica by cortex (but not meridian point), and detect at the corresponding sports position and to bring out electric pulse and be used to diagnose the instrument of nervous function and treatment hemiplegia to seem very few.What occur the earliest is the D180 type cerebral cortex stimulation instrument of Britain Digiter company, by dc source, charge and discharge electric capacity, isolating output transformer, output resistance, compositions such as switch, this stimulation instrument can only provide the electric pulse that stimulates cerebral cortex to use, and can only provide spike, fabric width is also non-adjustable, 88 years inventor Xu Jun, Xu Lanjun discloses the electric stimulating instrument after a kind of the improvement, the patent No. 88208858.0, it is by adjustable dc source, on-off circuit, output transformer, the pulse pulse-width modulator constitutes, the height of rectangular pulse takes place, width is scalable all, gained brings out current potential repeatability might as well, but at most also can only provide the same with the former stimulates corticocerebral pulse, do not possess the region of interest of detection and produce the function of bringing out current potential, in addition the pulse that provides only is a single, if go to diagnose nervous function to feel inconvenience with this instrument, as being used for the treatment of the hemiplegia sequela, it is too low that efficient is just disliked.
The objective of the invention is to disclose a kind of can providing stimulates corticocerebral pulse can detect the instrument that brings out current potential accordingly again, makes it not only can be effectively used to the nervous function diagnosis, and more can be advantageously used in hemiplegia sequela's treatment.
Its scheme is: a kind of maincenter stimulates hemiparalysis curing instrument, it is characterized in that by electric stimulating instrument and bring out potential detection device and form, electric stimulating instrument comprises high frequency switch power, on-off circuit, output transformer, pulse pulse-width modulator and train pulse generator, high frequency switch power output termination on-off circuit, on-off circuit output termination output transformer, pulse-series generator outfan order pulse pulse-width modulator input, pulse pulse-width modulator outfan is connected with on-off circuit with high frequency switch power simultaneously, bring out potential detection device and comprise the measurement amplifying unit, signal processing and display unit, measure amplifying unit output termination signal processing and display unit, the outfan of signal processing and display unit is connected with electric stimulating instrument.
Bring out potential detection device and also contain the biofeedback unit, this unit is provided with sound and light display spares such as loudspeaker, ammeter.
The train pulse generator is made up of oscillation source, enumerator, decoder, multi-gear switch and lock circuit, the pulse output end of oscillation source connects the enumerator input, counter output connects the decoder input, decoder output connects multi-gear switch, each of multi-gear switch grade corresponds respectively to different setting umber of pulses, and the pulse output end of oscillation source also is connected with lock circuit.
The biofeedback unit comprises a voltage follower, this voltage follower input termination is measured the amplifying unit outfan, its outfan is connected to loudspeaker, the size of speaker sound size reflection electromyographic signal, its outfan end also is connected to a clamping diode circuit and detecting circuit, detecting circuit is connected to ammeter, the size of the reading size reflection electromyographic signal of ammeter, detecting circuit connects some light emitting diodes through bleeder circuit and voltage detector, and the bright number of light emitting diode shows the size of electromyographic signal.
Output transformer is the magnetic saturation pulse transformer, and internal resistance is not less than 800 ohm.
In therapeutic instrument, be provided with the train pulse generator, therefore it sends is used for stimulating corticocerebral pulse and not only can is one but also can is amplitude, pulsewidth and all adjustable pulse train at interval, thereby can be transferred to the state of suitable treatment to therapeutic instrument, instrument itself is provided with the checkout gear that brings out current potential, can measure at any time, diagnostic function not only be arranged but also the function of checking therapeutic effect is arranged.
To and contrast accompanying drawing by embodiment below describes in detail:
The drawing explanation:
Fig. 1 is the block diagram of embodiment;
Fig. 2 is the structured flowchart of electric stimulating instrument;
Fig. 3 is high frequency switch power, on-off circuit and isolating transformer circuit diagram;
Fig. 4 is a pulse pulse-width modulator circuit diagram;
Fig. 5 is train pulse generator circuit figure;
Fig. 6 is biofeedback element circuit figure.
Embodiment is that a maincenter with bio-feedback arrangement stimulates hemiparalysis curing instrument, it is by electric stimulating instrument and bring out potential detection device and form, its electric stimulating instrument is made of high frequency switch power, on-off circuit, output circuit, pulse pulse-width modulator, train pulse generator, as shown in Figure 2.Comparing with correlation technique has increased the train pulse generator.High frequency switch power output termination on-off circuit, on-off circuit output termination output transformer, pulse-series generator outfan order pulse pulse-width modulator input, pulse pulse-width modulator outfan is connected with on-off circuit with high frequency switch power simultaneously.Its high-voltage DC power supply has adopted high frequency switch power, bring out potential detection device and comprise measurement amplifying unit, signal processing and display unit and biofeedback unit, measure the amplifying unit outfan and connect signal processing and display unit by the biofeedback unit, the outfan of signal processing and display unit is connected with electric stimulating instrument.Measure amplifying unit measurement electrode IN is arranged +, IN -, preposition amplification, isolation, the main amplification, signal processing and show and adopt A/D converter and computer.Certainly for the needs for a whole set of instrument also are provided with serial power supply, it is made up of transformator T1 ', power supply G2 and isolating transformer T2 ', T3 ', float power G1.
The train pulse generator as shown in Figure 5, its circuit has D, E, F not gate and resistance R 1, adjustable resistance R2, the capacitor C 1 of four part: IC8 to form oscillation source, the enumerator that six triggers of IC10, IC11, IC12 are formed, the lock circuit that the decoder of 8 NAND gate and a not gate formation and two NAND gate of IC6C, IC7D, two not gates of IC8B, C, IC9A trigger constitute among IC5, IC6, IC7, the IC8.Oscillation source is outwards exported the CP pulse, its outfan is received the input of enumerator simultaneously, enumerator connects decoder, a multi-gear switch K4 is received in decoder output, each grade is corresponding to 1,2,5,10,15,20,30,40,50 pulses, when having arrived the setting umber of pulse, the K4 output low level makes 12 feet of IC7D be low level, and the outfan of CP pulse is by locked (counting also stops).Therefore K4 output " 0 ", the D end of IC9A for " 0 " thus the next CP pulse back edge in back just makes the IC9A upset make IC7D block CP output, so the output pulse is complete and do not have half.
High frequency switch power is that the core formation is seen Fig. 3 with power switch pipe Tr3, and the collector circuit of Tr3 is the major loop of this power supply, is its drive circuit on the base stage.Tr3 is by the elementary connection filter capacitor of transformator T1 C1, commutator D1-D4 and wave filter L1, and T1 secondary connect capacitor C 3, diode D5, D6, capacitor C 4 and inductance L 3, capacitor C 5 successively, so that outfan J1-1, the J1-2 of power supply.The emitter stage of Tr3 is coupled on the colelctor electrode of driving tube Tr4 by transformator T4, the base stage of Tr4 (by R4 and IC2 three reverser A, B, C) is received the A of IC 1, monostable outfan that B two NAND gate constitute, and the input of monostable circuit is received the ring oscillator outfan that the F not gate of C, D two NAND gate and the IC2 of IC1 constitutes by the reverser E of IC2, the voltage sample circuit that a bit connects the high frequency switch power outfan of ring oscillator, and sample circuit is by R0, and Tr0, IC3, D10 and W1 constitute.Output end voltage was 0 when high frequency switch power started, sampling voltage also is 0, the ring oscillator starting of oscillation, periodic triggers monostable and monostable circuit periodic triggers Tr4, thus make periodically conducting of Tr4 Tr3, and T1's is elementary to secondary conveying capacity during conducting, ON time depends on monostable output pulse width, select ON time that the product of itself and L2 (leakage inductance) and C3+C4 is complementary, make Tr3 conducting and closing when other electric current, thus minimizing due to voltage spikes noise.The periodicity conducting of Tr3, the vibration of power supply main circuit voltage is raise until being raised to setting value, sample circuit extinguishes agitator, monostable circuit is no longer overturn, no longer conducting of Tr4 and Tr3, and main circuit voltage no longer raises, have only the voltage of working as to drop to setting value, ring oscillator just triggers monostable circuit, makes the Tr3 conducting once, power supply major loop makeup energy boosted voltage.The on-off circuit of electric stimulating instrument and output and correlation technique do not have big difference, the output pulse transformer magnetic saturation type, and the transformator internal resistance is 800 Ω, makes the energy of output unit pulse be lower than 300 milli Ji Er of medical device industry standard YY0016-93 regulation.
In curing hemiparalysis, patient's subjectivity is made great efforts and cooperated is very important, and for giving full play to patient's enthusiasm, instrument is provided with the biofeedback unit, and circuit is seen Fig. 6.Electromyographic signal is after amplifier unit amplifies, input biofeedback unit, at first, it is isolated and power amplification through the voltage follower that the IC1:A amplifier is formed, electromyographic signal AMP after promptly amplifying receives 3 feet of IC1:A, and 2 feet of IC1 link to each other with 1 foot and join with loudspeaker, the other end ground connection of loudspeaker, speaker sound little big, the size of reflection electromyographic signal.
1 foot of IC1 is also received the clamping diode circuit that capacitor C 1, C3, resistance R 1 and diode D1 form.1 foot of IC1 meets C1, the negative pole of another termination D1 of C1 and C3, R1, R2.The other end ground connection of the positive pole of D1 and C3, R1,5 feet of another termination IC1:B amplifier of R2.IC1:B amplifier and diode D2, capacitor C 2, E2 have formed detecting circuit.7 feet of IC1 connect the positive pole of D2, and the negative pole of D2 connects 6 ends of IC1:B amplifier, the anode of E2 and 13 feet of C2, resistance R 11, resistance R 10 and IC1:D amplifier.The other end ground connection of the negative terminal of E2 and C2.The anode of another termination ammeter A of R11, the ammeter negativing ending grounding, ammeter A shows the size of electromyographic signal.Resistance R 6, R5, R4, R3, R9, R10 form bleeder circuit.Another termination R9 of R10 and 9 feet of IC1:C amplifier.Another termination R3 of R9 and 13 feet of IC2:D amplifier.Another termination R4 of R3 and 9 feet of IC2:C amplifier, another termination R5 of R4 and 6 feet of IC2:B amplifier, another termination R6 of R5 and 2 feet of IC2:A amplifier, the other end ground connection of R6.R8 and R7 form potentiometer again, the end ground connection of its R8,12,10 feet of another termination R7 and IC1 and 13,9,6,2 feet of IC2, another termination 12V of R7.Four amplifiers of A, B, C, the D of the C of IC1, D two amplifiers and IC2 are formed six voltage comparators, the output of these six comparators is connected to the negative pole of light emitting diode L1, L2, L3, L4, L5, L6 respectively via resistance R 12, R13, R14, R15, R16, R17, and the light emitting diode positive pole is connected in the 12V power supply.The bright number of light emitting diode shows the electromyographic signal size.
In addition, the positive termination 12V of filter capacitor E1, negativing ending grounding, 11 feet of IC1 and 1C2,4 feet are connected to 12V and ground respectively.
Therefore, patient makes great efforts the motion sickness limb by oneself, the electromyographic signal that produces on the sick limb is after detecting amplification, make biofeedback unit generation sound, light, electricity (meter pointer deflection) signal, this signal acts on patient's sense organ, makes it strengthen treatment confidence, motion sickness limb harder, electromyographic signal is further strengthened, and sound, light, the signal of telecommunication send stronger signal.So positive feedback can increase therapeutic effect.
Except that above-mentioned feedback, this instrument also is provided with another kind of feedback, promptly move the disease limb by patient, from electromyographic signal that sick limb detects after amplification is sent to computer and is carried out signal processing, send in due course to allow and stimulate the order of instrument action, the cortical stimulation instrument sends electric pulse stimulation patient cortex corresponding sports district, makes it send the electric pulse of stronger order limb motion.Because cortical stimulation is made great efforts close the combination with patient's subjectivity, thereby also reaches better therapeutic effect.
This instrument also has the Motion Evoked Potential measuring ability.The cortical stimulation instrument stimulates patient's motor cortex, on corresponding limbs, draw and bring out current potential, carry out date processing through amplifying unit amplification and input computer, the waveform that can obtain Motion Evoked Potential shows and data, it can the detection by quantitative patient state of an illness situation of change, thereby for patient and doctor provide the objective quantitative Diagnosis conclusion of therapeutic effect, this also has direct and indirect effect for improving therapeutic effect.

Claims (5)

1, a kind of maincenter stimulates hemiparalysis curing instrument, it is characterized in that by electric stimulating instrument and bring out potential detection device and form, electric stimulating instrument comprises high frequency switch power, on-off circuit, output transformer, pulse pulse-width modulator and train pulse generator, high frequency switch power output termination on-off circuit, on-off circuit output termination output transformer, pulse-series generator outfan order pulse pulse-width modulator input, pulse pulse-width modulator outfan is connected with on-off circuit with high frequency switch power simultaneously, bring out potential detection device and comprise the measurement amplifying unit, signal processing and display unit, measure amplifying unit output termination signal processing and display unit, the outfan of signal processing and display unit is connected with electric stimulating instrument.
2, therapeutic instrument as claimed in claim 1 is characterized in that: bring out potential detection device and also contain the biofeedback unit, this unit is provided with sound and light display spares such as loudspeaker, ammeter.
3, therapeutic instrument as claimed in claim 1, it is characterized in that: the train pulse generator is made up of oscillation source, enumerator, decoder, multi-gear switch and lock circuit, the pulse output end of oscillation source connects the enumerator input, counter output connects the decoder input, decoder output connects multi-gear switch, each of multi-gear switch grade corresponds respectively to different setting umber of pulses, and the pulse output end of oscillation source also is connected with lock circuit.
4, therapeutic instrument as claimed in claim 2, it is characterized in that: the biofeedback unit comprises a voltage follower, this voltage follower input termination is measured the amplifying unit outfan, its outfan is connected to loudspeaker, the size of speaker sound size reflection electromyographic signal, its outfan end also is connected to a clamping diode circuit and detecting circuit, detecting circuit is connected to ammeter, the size of the reading size reflection electromyographic signal of ammeter, detecting circuit connects some light emitting diodes through bleeder circuit and voltage detector, and the bright number of light emitting diode shows the size of electromyographic signal.
5, as claim 1,2,3 or 4 described therapeutic instruments, it is characterized in that: output transformer is the magnetic saturation pulse transformer, and internal resistance is not less than 800 ohm.
CN97116097A 1997-09-05 1997-09-05 Hemiparalysis curing instrument by central nervous stimulation Expired - Fee Related CN1085100C (en)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102068744A (en) * 2010-11-29 2011-05-25 邓艳春 Electroencephalic monitoring-sensory stimulation waking integrated therapeutic apparatus
CN102058396B (en) * 2011-01-28 2013-06-05 广州军区广州总医院 Handheld cortex egersimeter and cortex electrostimulation

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN2043120U (en) * 1988-07-23 1989-08-23 河南省老年病研究中心 Electric stimulator
CN1088121A (en) * 1992-12-14 1994-06-22 上海交通大学 Myoelectric feedback paralysis due to windstroke therapeutic instrument

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN2043120U (en) * 1988-07-23 1989-08-23 河南省老年病研究中心 Electric stimulator
CN1088121A (en) * 1992-12-14 1994-06-22 上海交通大学 Myoelectric feedback paralysis due to windstroke therapeutic instrument

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