CN108498061A - Miniature cystoscope probe and cystoscope system for portable medical - Google Patents

Miniature cystoscope probe and cystoscope system for portable medical Download PDF

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Publication number
CN108498061A
CN108498061A CN201810091848.8A CN201810091848A CN108498061A CN 108498061 A CN108498061 A CN 108498061A CN 201810091848 A CN201810091848 A CN 201810091848A CN 108498061 A CN108498061 A CN 108498061A
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CN
China
Prior art keywords
cystoscope
optical
probe
miniature
portable medical
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201810091848.8A
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Chinese (zh)
Inventor
罗敏敏
郭青春
董才俊
田真真
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Thinker Tech Nanjing Biotech Ltd Co
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Thinker Tech Nanjing Biotech Ltd Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Thinker Tech Nanjing Biotech Ltd Co filed Critical Thinker Tech Nanjing Biotech Ltd Co
Priority to CN201810091848.8A priority Critical patent/CN108498061A/en
Publication of CN108498061A publication Critical patent/CN108498061A/en
Pending legal-status Critical Current

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/307Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor for the urinary organs, e.g. urethroscopes, cystoscopes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/00002Operational features of endoscopes
    • A61B1/00011Operational features of endoscopes characterised by signal transmission
    • A61B1/00016Operational features of endoscopes characterised by signal transmission using wireless means
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/04Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor combined with photographic or television appliances
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/06Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor with illuminating arrangements
    • A61B1/07Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor with illuminating arrangements using light-conductive means, e.g. optical fibres

Abstract

The present invention proposes a kind of miniature cystoscope probe and cystoscope system for portable medical, and the probe includes optical lens, supporting rack, optical imagery chip and the flexible light optical waveguide of shell and enclosure setting;The optical lens is fixed on supporting rack;The optical imagery chip is located at the image planes position of optical lens imaging;The system comprises probe, lighting source, imaging signal processing circuit and acquisition display terminals;It is combined with optical lens, flexible light optical waveguide using optical imagery chip, shorten pass image distance from, picture signal directly acquires after imaging len, can obtain the picture quality of high contrast and resolution ratio, provides data for accurate lesion and condition-inference and supports;Improve contrast and resolution ratio;Flexible light optical waveguide is used simultaneously, improves the flexibility of cystoscope entirety.

Description

Miniature cystoscope probe and cystoscope system for portable medical
Technical field
The present invention relates to medical detection technology, more particularly to a kind of miniature cystoscope probe for portable medical and Cystoscope system.
Background technology
Cystoscope is a kind of common intrusive detection device of clinical diagnosis disease in the urological system, by by lighting source and Imaging system is inserted into bladder through per urethram uplink and to urinary organs such as ureters, is carried out to the surface texture of related internal organs real When imaging, using the direct basis as diagnosis of urinary diseases.Existing cystoscope is generally divided into two kinds of hardness and flexibility, firmly Property cystoscope mirror body and imaging mechanism be encapsulated in the metal tube that one can not be bent, flexible cystoscope then usually utilize it is soft Property fiber optic bundle carry out biography picture, have certain bending ability.Due to physiological reason, the urethral structures of male are relative complex, in profit It was often checked since mirror body and urethral canal inner wall friction bring huge pain and bleeding when carrying out cystoscopy with hardness It generally requires to anaesthetize sb. generally to sufferer in journey.Flexible cystoscope can be reduced by itself bending and be rubbed with urethral canal inner wall It wipes, to reduce the risk that is painful and causing complication of sufferer, usually only needs to carry out local anaesthesia to check point. Flexibility cystoscope is typically to be realized by installing the method for imaging len additional in fiber optic bundle front end at present, and diameter can also control 2mm or so greatly alleviates the painful experience of sufferer during the inspection process.However, since fiber optic bundle is made using fiber array For image guide device, light loss of energy is had during long distance transmission, and can be formed on the image device of end and fiber optic bundle The consistent honeycomb-like pattern of structure, leads to the decline of image contrast and resolution ratio, this is accurate by image for diagnostician Identification lesion and judge that the state of an illness will produce certain influence.And fiber optic bundle is glass fibre material, in flexibility yet There are certain shortcomings.Therefore, it is necessary to which further to cystoscope regarding to the issue above improved.
Invention content
The purpose of the present invention aims to solve at least one of the technological deficiency.
To achieve the goals above, the embodiment of one aspect of the present invention provides a kind of miniature cystoscope for portable medical Probe, the probe stretch to affected area, the probe includes shell and enclosure is arranged optical lens, supporting rack, Optical imagery chip and flexible light optical waveguide;The optical lens is fixed on supporting rack;The optical imagery chip is located at The image planes position of optical lens imaging;
The optical lens, be by multi-disc lens arrangement at compound lens, the optical lens is used for observing object Body is imaged onto optical imagery chip surface;
The optical imagery chip, the real image conversion of the object for optical lens to be imaged on to optical imagery chip surface At electrical image signal;
The flexible light optical waveguide, is coated on the inner wall of shell, and the flexible light optical waveguide is used for external photograph Mingguang City source is transmitted to probe distal end.
Preferably, the diameter range of the probe is 1.5~3.3mm.
Preferably, PCB circuit board is equipped in the probe, the optical imagery integrated chip is described in PCB circuit board PCB circuit board connects data line, is used for transmission detected electrical image signal of popping one's head in.
Preferably, further include the optical filter being arranged on supporting rack, the optical filter is located at optical lens and optical imagery Between chip, for filtering out bias light and interference light other than detection wavelength.
Preferably, the shell exterior of the probe coats protection sleeve pipe;The front end of the protection sleeve pipe uses rigid material It is made, rear end protection sleeve pipe is made using flexible material.
The present invention also provides a kind of miniature cystoscope systems for portable medical, including probe described above, illumination Light source, imaging signal processing circuit and acquisition display terminal;
The flexible light optical waveguide of the lighting source connection probe;For being carried for the flexible light optical waveguide of the probe For light source;
Described image signal processing circuit, the electrical image letter for the optical imagery chip formation that receiving transducer is sent Number;And noise reduction process is filtered to the electrical image signal, and will treated that electrical image signal is sent to acquisition is aobvious Show that terminal is shown;
The acquisition display terminal, for receive imaging signal processing circuit transmission electrical image signal, and according to Family instruction is amplified and moves to the electrical image signal of display.
Preferably, image procossing is carried out using following algorithm in described image signal processing circuit:Step 1, to optics at The electrical image signal formed as chip carries out histogram equalization processing, according to the gray scale of pixel value aggregation zone in histogram Value carries out gray areas division;Step 2, according to the gray areas of above-mentioned division, corresponding parabolic is respectively adopted to corresponding region Line function is enhanced or is inhibited;Enhanced image is sharpened and smothing filtering by step 3.
Preferably, when gray areas described in step 1 divides, the maximum value of acquisition pixel value distributed areas gray value and most Small value, according to the pixel value being distributed between maximum value and minimum value number, set gray value region gradient;According to gray value area Domain gradient is divided into dark space, clear zone and transition region.
Preferably, described image processing circuit includes DSP picture processing chips and is connected respectively with DSP picture processing chips Jtag interface, A/D conversion modules, the Video Output Modules connect;The jtag interface is for downloading image processing algorithm to DSP figures As processing chip;The DSP picture processing chips be used for according to image processing algorithm carry out image procossing, and will treated figure As being transmitted to acquisition display terminal by Video Output Modules.
Preferably, described image processing circuit connects wireless communication module, and the wireless communication module is used for will be at image Picture signal after reason processing of circuit is wirelessly transferred.
A kind of miniature cystoscope probe and cystoscope system for portable medical provided according to embodiments of the present invention, phase Than being had at least the following advantages in existing cystoscope system:
1, it is combined with optical lens, flexible light optical waveguide using optical imagery chip, shortens and pass image distance from image Signal directly acquires after imaging len, can obtain the picture quality of high contrast and resolution ratio, is accurate lesion and disease Feelings diagnosis provides data and supports;Improve contrast and resolution ratio;Flexible light optical waveguide is used simultaneously, and it is whole to improve cystoscope The flexibility of body.
2, the outer diameter of probe is accomplished into 1.5mm, the pain of sufferer can be mitigated to greatest extent.
3, it realizes integrated illumination using flexible optical waveguide, may be implemented by replacing optical filter in lighting source and probe Different imaging modes is had potential application with adapting to different observation objects.
4, picture signal forms specific wired or wireless communication output format (such as USB, wifi) by processing circuit, can To connect mobile internet and intelligent communications terminal, tele-medicine is realized, and can be realized in conjunction with mobile network's technology remote Journey medical treatment, improves the diagnostic level of remote districts.
The additional aspect of the present invention and advantage will be set forth in part in the description, and will partly become from the following description Obviously, or practice through the invention is recognized.
Description of the drawings
The above-mentioned and/or additional aspect and advantage of the present invention will become in the description from combination following accompanying drawings to embodiment Obviously and it is readily appreciated that, wherein:
Fig. 1 is the structural schematic diagram that a kind of miniature cystoscope for portable medical provided in an embodiment of the present invention is popped one's head in;
Fig. 2 is a kind of structural schematic diagram of miniature cystoscope system for portable medical provided in an embodiment of the present invention;
Fig. 3 is image processing algorithm in a kind of miniature cystoscope system for portable medical provided in an embodiment of the present invention Flow chart.
In figure:1, optical lens;2, optical filter;3, supporting rack;4, optical imagery chip;5, PCB circuit board;6, data Line;7, flexible light optical waveguide;8, protective case;9, lighting source;10, imaging signal processing circuit;11, display terminal is acquired.
Specific implementation mode
The embodiment of the present invention is described below in detail, examples of the embodiments are shown in the accompanying drawings, wherein from beginning to end Same or similar label indicates same or similar element or element with the same or similar functions.Below with reference to attached The embodiment of figure description is exemplary, it is intended to for explaining the present invention, and is not considered as limiting the invention.
As shown in Figure 1, a kind of miniature cystoscope for portable medical of the embodiment of the present invention is popped one's head in, the probe stretches into To affected area, the probe includes shell and optical lens 1, supporting rack 3,4 and of optical imagery chip of enclosure setting Flexible light optical waveguide 7;Optical lens 1 is fixed on supporting rack 3;Optical imagery chip 4 is located at the image planes of the imaging of optical lens 1 Position;
Optical lens 1 be by multi-disc lens arrangement at compound lens, compound lens as a whole, by observed object at As arriving 4 surface of optical imagery chip;Optical imagery chip 4, for optical lens 1 to be imaged on 4 surface of optical imagery chip The real image of object is converted into electrical image signal;Further include the optical filter 2 being arranged on supporting rack 3, optical filter 2 is located at optical frames Between first 1 and optical imagery chip 4, for filtering out bias light and interference light other than detection wavelength.
Flexible light optical waveguide 7 is coated on the inner wall of shell, and flexible light optical waveguide 7 is used for external lighting source 9 It is transmitted to probe distal end.The diameter range of probe is 1.5~3.3mm.The pain of sufferer can be mitigated to greatest extent.
PCB circuit board 5 is equipped in probe, optical imagery chip 4 is integrated in PCB circuit board 5, and PCB circuit board 5 connects number According to line 6, it is used for transmission detected electrical image signal of popping one's head in.
The shell exterior cladding protective case 8 of probe is managed;The front end of 8 pipe of protective case is made of rigid material, rear end protection 8 pipes are covered to be made using flexible material.Flexible optical waveguide is evenly distributed on the outside of lens and supporting rack, is used in combination rigid casing same Axis is fixed and is encapsulated.The part that data line and flexible optical waveguide stretch out probe is packaged and protects using flexible sleeve, it is non-at It is filled and is fixed with medical glue as light path linking gap.
In one embodiment of the invention, the present invention uses the micro-optical imager chip 4 of Highgrade integration, chip ruler Very little minimum 0.575mm × 0.575mm is connected by PCB circuit board 4 with data line 5.Picture signal passes through data line junction Circuit 10 is managed, specific communication output format is formed, is acquired and shown by acquisition terminal 11 eventually by corresponding interface.Acquisition Terminal can be not only common PC, can also be that the handhold portables such as tablet or mobile phone display storage terminal is set It is standby.Optical imagery chip is closed by supporting rack 3 and the position that optical lens 1 and optical filter 2 by aberration correction are kept fixed System, to realize that probe keeps the optical indexes such as specific operating distance, enlargement ratio and aberration characteristic.Flexible light optical waveguide 7 It is coupled with light source 9 in outside, end is concordant with optical lens, and for lighting source to be transferred to probe front, light may be used It is fine or other have certain flexible optical material, it is external by the way that rigidity and flexible protective casing 8 be unified fixed and protection. In the present invention white light colour imaging can be realized respectively (white-light illuminating is with close red by replacing external light source 9 and filtered inside piece 2 Outer edge filter) and specific wavelength fluorescence imaging (blue illumination with 525nm bandpass filters be used for green fluorescent protein It is imaged), to observe different detection objects.
As shown in Fig. 2, the present invention also provides a kind of miniature cystoscope system for portable medical, including above-mentioned spy Head, lighting source 9, imaging signal processing circuit 10 and acquisition display terminal;The flexible light light wave of the connection probe of lighting source 9 Lead 7;For providing light source for the flexible light optical waveguide 7 of probe;Imaging signal processing circuit 10 is sent for receiving transducer The electrical image signal that optical imagery chip 4 is formed;And noise reduction process is filtered to electrical image signal, and by treated Electrical image signal is sent to acquisition display terminal and shows;Display terminal is acquired, is sent out for receiving imaging signal processing circuit 10 The electrical image signal sent, and the electrical image signal of display is amplified and is moved according to user instruction.
As shown in figure 3, in one embodiment of the invention, being carried out using following algorithm in imaging signal processing circuit 10 Image procossing:Step 1 carries out histogram equalization processing to the electrical image signal that optical imagery chip is formed, according to histogram The gray value of pixel value aggregation zone carries out gray areas division in figure;Step 2, according to the gray areas of above-mentioned division, to phase Answering region that corresponding parabolic function is respectively adopted is enhanced or is inhibited;Enhanced image is sharpened peace by step 3 Sliding filtering.
Further, when gray areas divides in step 1, the maximum value and minimum of acquisition pixel value distributed areas gray value Value, according to the pixel value being distributed between maximum value and minimum value number, set gray value region gradient;According to gray value region Gradient is divided into dark space, clear zone and transition region.Specifically, according to the gray value of pixel value aggregation zone in histogram, ash discharge is obtained Change modeling curve is spent, in an embodiment of the present invention, using parabolic function as matched curve, ginseng is selected in transition region Examination point;Abscissa:Gray value;Ordinate:Pixel value;If the gray value corresponding to the pixel value of selected reference point is more than former throw The gray value of the point on object line then copes with the dark space on the left of reference point and sets the smaller parabolic function of curvature, carries out dark space increasing By force;Curvature is set as negative and the parabolic function of higher value to the clear zone on the right side of reference point, carries out clear zone inhibition.
If the gray value corresponding to the pixel value of selected reference point is less than the gray value of the point on former parabola, cope with Dark space on the left of reference point sets the larger parabolic function of curvature, carries out dark space enhancing;To the clear zone setting on the right side of reference point The smaller parabolic function of counter curvature carries out clear zone inhibition.
Image processing circuit includes that DSP picture processing chips and the JTAG being connected respectively with DSP picture processing chips connect Mouth, A/D conversion modules, Video Output Modules;Jtag interface is for downloading image processing algorithm to DSP picture processing chips;DSP Picture processing chip is used to carry out image procossing according to image processing algorithm, and image is passed by Video Output Modules by treated Transport to acquisition display terminal.
Image processing circuit connect wireless communication module, wireless communication module be used for by image processing circuit treated figure As signal is wirelessly transferred.
In the description of this specification, reference term " one embodiment ", " some embodiments ", " example ", " specifically show The description of example " or " some examples " etc. means specific features, structure, material or spy described in conjunction with this embodiment or example Point is included at least one embodiment or example of the invention.In the present specification, schematic expression of the above terms are not Centainly refer to identical embodiment or example.Moreover, particular features, structures, materials, or characteristics described can be any One or more embodiments or example in can be combined in any suitable manner.
Although the embodiments of the present invention has been shown and described above, it is to be understood that above-described embodiment is example Property, it is not considered as limiting the invention, those skilled in the art are not departing from the principle of the present invention and objective In the case of can make changes, modifications, alterations, and variations to the above described embodiments within the scope of the invention.The scope of the present invention By appended claims and its equivalent limit.

Claims (10)

1. a kind of miniature cystoscope for portable medical is popped one's head in, which is characterized in that the probe stretches to affected area, the spy Head includes shell and optical lens, supporting rack, optical imagery chip and flexible light optical waveguide that enclosure is arranged;It is described Optical lens is fixed on supporting rack;The optical imagery chip is located at the image planes position of optical lens imaging;
The optical lens, be by multi-disc lens arrangement at compound lens, the optical lens be used for by observed object at As arriving optical imagery chip surface;
The optical imagery chip is converted into electricity for optical lens to be imaged on to the real image of object of optical imagery chip surface Learn picture signal;
The flexible light optical waveguide, is coated on the inner wall of shell, and the flexible light optical waveguide is used for external illumination light Source is transmitted to probe distal end.
2. the miniature cystoscope according to claim 1 for portable medical is popped one's head in, which is characterized in that the probe it is straight Diameter ranging from 1.5~3.3mm.
3. the miniature cystoscope according to claim 1 for portable medical is popped one's head in, which is characterized in that set in the probe There is PCB circuit board, the optical imagery integrated chip is in PCB circuit board, and the PCB circuit board connects data line, for passing The detected electrical image signal of defeated probe.
4. the miniature cystoscope according to claim 1 for portable medical is popped one's head in, which is characterized in that further include that setting exists Optical filter on supporting rack, the optical filter between optical lens and optical imagery chip, for filter out detection wavelength with Outer bias light and interference light.
5. the miniature cystoscope according to claim 1 for portable medical is popped one's head in, which is characterized in that outside the probe Protection sleeve pipe is coated outside shell;The front end of the protection sleeve pipe is made of rigid material, and the rear end of protection sleeve pipe is using flexible Material is made.
6. a kind of miniature cystoscope system for portable medical, which is characterized in that including any one in the claims 1-5 Probe, lighting source, imaging signal processing circuit described in and acquisition display terminal;
The flexible light optical waveguide of the lighting source connection probe;For providing light for the flexible light optical waveguide of the probe Source;
Described image signal processing circuit, the electrical image signal for the optical imagery chip formation that receiving transducer is sent;And Noise reduction process is filtered to the electrical image signal, and electrical image signal is sent to acquisition display terminal by treated Display;
The acquisition display terminal, the electrical image signal for receiving imaging signal processing circuit transmission, and referred to according to user Order is amplified and moves to the electrical image signal of display.
7. a kind of miniature cystoscope system for portable medical according to claim 6, which is characterized in that described image Image procossing is carried out using following algorithm in signal processing circuit:
Step 1 carries out histogram equalization processing to the electrical image signal that optical imagery chip is formed, according to picture in histogram The gray value of element value aggregation zone carries out gray areas division;
Step 2, according to the gray areas of above-mentioned division, to corresponding region be respectively adopted corresponding parabolic function carry out enhancing or Inhibit;
Enhanced image is sharpened and smothing filtering by step 3.
8. a kind of miniature cystoscope system for portable medical according to claim 7, which is characterized in that in step S1 When the gray areas divides, the maximum value and minimum value of acquisition pixel value distributed areas gray value, according to maximum value and minimum The pixel value being distributed between value number, set gray value region gradient;It is divided into dark space, clear zone according to gray value region gradient And transition region.
9. a kind of miniature cystoscope system for portable medical according to claim 7, which is characterized in that described image Processing circuit includes DSP picture processing chips and the jtag interface being connected respectively with DSP picture processing chips, A/D moduluss of conversion Block, Video Output Modules;The jtag interface is for downloading image processing algorithm to DSP picture processing chips;The DSP images Processing chip is used to carry out image procossing according to image processing algorithm, and image is transmitted to by Video Output Modules by treated Acquire display terminal.
10. a kind of miniature cystoscope system for portable medical according to claim 7, which is characterized in that the figure As processing circuit connects wireless communication module, the wireless communication module is used for image processing circuit treated picture signal It is wirelessly transferred.
CN201810091848.8A 2018-01-30 2018-01-30 Miniature cystoscope probe and cystoscope system for portable medical Pending CN108498061A (en)

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CN201810091848.8A CN108498061A (en) 2018-01-30 2018-01-30 Miniature cystoscope probe and cystoscope system for portable medical

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Cited By (1)

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