CN1084753A - A kind of quick results detumescence pain stop paste and preparation method - Google Patents
A kind of quick results detumescence pain stop paste and preparation method Download PDFInfo
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- CN1084753A CN1084753A CN 93101614 CN93101614A CN1084753A CN 1084753 A CN1084753 A CN 1084753A CN 93101614 CN93101614 CN 93101614 CN 93101614 A CN93101614 A CN 93101614A CN 1084753 A CN1084753 A CN 1084753A
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Abstract
The invention discloses the novel medicine for external use of a kind of orthopaedics, it contains Radix Angelicae Sinensis, Rhizoma Chuanxiong, Flos Carthami, Radix Notoginseng, Radix Rubiae, Radix Paeoniae Rubra, Olibanum, Myrrha, Sanguis Draxonis, Herba Ephedrae, Pericarpium Citri Reticulatae Viride, Fructus Aurantii, makes ointment and is applied on the carrier of the present invention.
Description
The invention belongs to field of traditional Chinese, relate to a kind of orthopaedics novel external used medicine He Shi quick results detumescence pain stop paste and compound method thereof.
Current, the orthopaedics therapy medicine is many based on oral medicine, though medicine for external use has liniment, wash, plaster etc., but these medicines use central due to illness kind and patient's different demands and its limitation is arranged at it.Especially present externally applied ointment, permeability is poor after being affixed on the affected part, cause skin itching easily, redness, and owing to the carrier of present externally applied ointment lacks flexibility, skin-tightening can not get relaxing during use, patient uses a fault sense of discomfort, is difficult for being accepted, and especially service time is than long patient, the limit difficulty is adhered to continuous use, directly has influence on the curative effect of medicine.
The present invention then is the defective that exists in the above-mentioned prior art, prescription again, and it is good to have developed a kind of permeability, the novel pain stop ointment that medicine is absorbed easily, reducing swelling and alleviating pain is respond well.
The used prescription of ointment of the present invention is He Shi orthopaedics successor He Tian assistant present inventor's a secret recipe handed down in the family.He Shi orthopaedics is one of famous school of Sichuan, modern China traditional Chinese medical science orthopaedics three big streams, is founded by the special Hu Shi of Meng ethnic group, with going into another name for Sichuan Province clearly.He Shi orthopaedics melts illiteracy, full, Han nationality's medicine and pharmacology and wushu thereof, and modern age the doctor trained in Western medicine orthopaedics and tranmstology and biomechanics be one, its logos, side, the existing Chinese medicine and pharmacy characteristic of medicine are established one's own system again.With " Gu damage one card is from blood opinion, more heavily gas ", unique theoretical its signs that is such as " control bone and control meat earlier ".Because of it arrogates to oneself difficult osteopathia such as controlling common injury of orthopaedics department, particularly osteomyelitis, Pan Xi Shi disease, so enjoyed great prestige at home and abroad already.
The present invention had both met Chinese medicine cooperative effect principle and existing pharmacopeia standard with medicine, had special dose proportioning again; Manufacture method keep natural drug originality original flavor and ancient times secret proved recipe curative effect; Pharmaceutical carrier novelties etc. are the major technology feature.Purpose is, with novel external used medicine of orthopaedics and compound method thereof, improves the orthopaedics clinical efficacy, expands the ancient prescription range of application, abundant and development Chinese medicine preparation technology.
The present invention realizes like this.
At first prepare ointment.
Prescription consists of: (consumption is a weight ratio, and unit is in gram)
Radix Angelicae Sinensis 10-20 Rhizoma Chuanxiong 10-20 Flos Carthami 10-20 Radix Notoginseng 10-20
Pericarpium Citri Reticulatae Viride 10-20 Fructus Aurantii 10-20 Radix Rubiae 8-10 Radix Paeoniae Rubra 8-10
Olibanum 10-15 Myrrha 10-15 Sanguis Draxonis 5-10 Herba Ephedrae 5-10
Processing technique is:
Adopt alcohol and water to soak and extract active ingredient, the spissated method processing of heating; Make ointment, repaste is made ointment of the present invention on plaster carrier of the present invention.Specific embodiments is:
The crude drug of above-mentioned prescription is cleaned,, put 4-6 hour, take by weighing each medicine, pulverize and be powder (about 16 orders) by said ratio in sombre dry place's cold through 40-50 ℃ of oven drying 4-6 hour.With refining pure grain Chinese liquor warm macerating medicated powder, wine is 1-2 with the ratio of medicated powder by volume earlier: 1, and continuous dipping three times, temperature＜50 ℃ each 2-3 hour.Gradation leaching soak is soaked in water in the same way again.Mixed three wine soaks, till reclaiming ethanol to ethanol and stop to ooze with distillation under vacuum, pressure is controlled at soak temperature＜65 ℃ when reclaiming ethanol.Soak behind the recovery ethanol and three water soaks is mixed, and (＜70 ℃) evaporation moisture content of heating is condensed into ointment: water ≈ 1.4-2: 1 thick paste.Be as the criterion with the thick paste gross weight, in thick paste, add benzoic acid 1%, 5% glycerol and Borneolum Syntheticum each 5%, the ethanol of recovery (concentration 84%-90%) is an amount of, till reaching 1: 1 to denseness.
The carrier for preparing plaster of the present invention then.
Plaster of the present invention looks for body to be made up of two parts: the one, tensoplast (as commercially available Bandaid adhesive plaster), moreover be the medical poisonless sponge combines the two according to shown in Figure 1, superincumbent 1 represents medical sponge, below 2 are Bandaid adhesive plasters.
Prepare plaster of the present invention at last:
By the dosage of every obedient 5g, 7g, 9g ointment, with ointment be coated with into 4 * 6,8 * 10 respectively, 12 * 18(sponge area cm
2) carrier of specification, stick nontoxic lid lining paper, continuous at once 4 hours ultraviolet radiation, the sampling antibacterial culturing detect qualified after, be the non-toxic plastic bag of tinfoil paper with the medicine card internal layer of packing into, the bag mouth heat seal.Promptly get He Shi quick results detumescence pain stop paste finished product.
Raw material of the present invention is easy to get, method is easy to grasp, reliable for effect.Has stronger blood circulation promoting and blood stasis dispelling, the circulation of qi promoting stagnant effect that disappears, the zoopery proof can significantly be alleviated rabbit peripheral blood vessel smooth muscle spasm and reduce rat lower limb vascular resistance, so the treatment because of the fracture or soft tissue injury due to swelling, pain, can promptly play the effect of detumescence, analgesic therapy, and the healing that can quicken to fracture.In recent years domestic three tame medical institutions He Shi quick results detumescence pain stop pastes, treatment fracture, soft tissue injury, systematic observation routine patient's clinical efficacy surplus 700, confirm effective percentage 95%, cure rate 90%, have no side effect, effect is better than similar Chinese medicine and relevant Western medicine.The present invention had both fully extracted the active ingredient of medicine, did not change its physicochemical property again, had kept the originality original flavor of natural drug.Novel carrier can strengthen the saturating speed of medicine when skin absorbs, and can keep effective wettability of ointment, and is firm with skin-adherent, is easy to coincide with the affected part body, and non-stimulated or sensitization is not subjected to effects limit such as region, temperature, science, practical.
Embodiment:
Prescription: Radix Angelicae Sinensis 100 gram Rhizoma Chuanxiongs 100 gram Flos Carthamis 100 gram Radix Notoginseng 100 grams
Pericarpium Citri Reticulatae Viride 100 gram Fructus Aurantiis 100 gram Radix Rubiaes 80 gram Radix Paeoniae Rubra 80 grams
Olibanum 90 gram Myrrhas 90 gram Sanguis Draxonis 60 gram Herba Ephedraes 60 grams
Above-mentioned prescription drug is cleaned, put into porcelain dish, put in the far infrared baking oven, in 45 ℃ of dry 4-6 hours, take out and put into exsiccator, placed 5 hours at the place in the cool place, pulverizing is 16 purpose medicated powder, soak with 52 ° of degree pure grain wines, the volume ratio of wine and medicated powder is 1.5: 1, temperature＜50 ℃, continuous dipping three times, each 2 hours, gradation leaching soak was soaked in water in the same way again.The wine soak is put in the concentrating under reduced pressure pot, and controlled pressure ℃ exceeds with soak temperature＜60, carries out ethanol and reclaims, till stopping to drip to ethanol.The soak that reclaims behind the ethanol is mixed with the water soak, put in the interlayer caldron, steam heated ℃ is exceeded with soak temperature＜65, and be evaporated to water: 1: 1.45 denseness of ointment ≈ gets final product, and must restrain by ointment about 350.Add each 17.5 gram of benzoic acid 35 grams, 5% glycerol and Borneolum Syntheticum, reclaim about 2.5 grams of ethanol 0.6%-10%(), ointment denseness 1: 1.By every obedient 7 gram dosage standards, ointment is coated with into 8 * 10(sponge area (cm
2) standby carrier, lining, sterilization, detection, encapsulation.Promptly get 57 obedient He Shi quick results detumescence pain stop pastes.
Claims (6)
1, a kind of reducing swelling and alleviating pain ointment, it contains: (consumption is a weight ratio)
Radix Angelicae Sinensis 10-20 Rhizoma Chuanxiong 10-20 Flos Carthami 10-20 Radix Notoginseng 10-20
Pericarpium Citri Reticulatae Viride 10-20 Fructus Aurantii 10-20 Radix Rubiae 8-10 Radix Paeoniae Rubra 8-10
Olibanum 10-15 Myrrha 10-15 Sanguis Draxonis 5-10 Herba Ephedrae 5-10
2, according to the ointment of claim 1, it is characterized in that also adding in the above-mentioned ointment benzoic acid 1%, 5% glycerol and Borneolum Syntheticum each 5%, ethanol 0.6%-1%(percentage composition is in the ointment gross weight).
3,, it is characterized in that said concentration of alcohol is 84%-90% according to the ointment of claim 2
4, a kind of preparation method of swelling-reducing pain-easing ointment is characterized in that earlier the medicine of following prescription being made extractum: (consumption is a weight ratio)
Radix Angelicae Sinensis 10-20 Rhizoma Chuanxiong 10-20 Flos Carthami 10-20 Radix Notoginseng 10-20
Pericarpium Citri Reticulatae Viride 10-20 Fructus Aurantii 10-20 Radix Rubiae 8-10 Radix Paeoniae Rubra 8-10
Olibanum 10-15 Myrrha 10-15 Sanguis Draxonis 5-10 Herba Ephedrae 5-10
Get above-mentioned crude drug and clean oven dry, pulverize, adding brewing grains white spirit heats and soaks three times, the volume ratio of wine and medicated powder is 1-2: 1, three soaks filter and merge, and water soaks in the same way again, with the ethanol in the distillation under vacuum recovery soaking in Chinese liquor liquid, merge with the water soak then, be concentrated into ointment: water=1.4-2: 1 thick paste.In the thick paste gross weight, in thick paste, add benzoic acid 1%, 5% glycerol and Borneolum Syntheticum each 5%, ethanol 0.6%-1% is applied to the gained ointment on the plaster carrier then.
5, according to the method for claim 4, the temperature of wherein heating when soaking is＜50 ℃, the each 2-3 of soak time hour, adds concentration of ethanol 84%-94% in the thick paste.
6, according to the method for claim 4, wherein said plaster carrier is made up of tensoplast (2) and medical sponge (1), and medical sponge (1) is attached to tensoplast (2) rubberised layer, as the absorbed layer of pharmaceutical carrier.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN93101614A CN1055834C (en) | 1993-02-18 | 1993-02-18 | Quick results detumescence pain stop paste and preparing process |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN93101614A CN1055834C (en) | 1993-02-18 | 1993-02-18 | Quick results detumescence pain stop paste and preparing process |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1084753A true CN1084753A (en) | 1994-04-06 |
| CN1055834C CN1055834C (en) | 2000-08-30 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN93101614A Expired - Fee Related CN1055834C (en) | 1993-02-18 | 1993-02-18 | Quick results detumescence pain stop paste and preparing process |
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| Country | Link |
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| CN (1) | CN1055834C (en) |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1059100C (en) * | 1996-04-08 | 2000-12-06 | 魏贯东 | Ointment for subsidence of swelling and relieving pain |
| CN1062747C (en) * | 1995-01-14 | 2001-03-07 | 冯成林 | Fracture setting medicine |
| CN104001123A (en) * | 2014-06-21 | 2014-08-27 | 李宝 | Police anti-explosion spray cleaning agent |
| CN109730832A (en) * | 2019-01-04 | 2019-05-10 | 湖北健身医疗器械有限公司 | A kind of plaster and its application |
| CN111759973A (en) * | 2020-08-17 | 2020-10-13 | 何鑫 | A Chinese medicinal preparation for treating traumatic injury, and its preparation method |
-
1993
- 1993-02-18 CN CN93101614A patent/CN1055834C/en not_active Expired - Fee Related
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1062747C (en) * | 1995-01-14 | 2001-03-07 | 冯成林 | Fracture setting medicine |
| CN1059100C (en) * | 1996-04-08 | 2000-12-06 | 魏贯东 | Ointment for subsidence of swelling and relieving pain |
| CN104001123A (en) * | 2014-06-21 | 2014-08-27 | 李宝 | Police anti-explosion spray cleaning agent |
| CN109730832A (en) * | 2019-01-04 | 2019-05-10 | 湖北健身医疗器械有限公司 | A kind of plaster and its application |
| CN111759973A (en) * | 2020-08-17 | 2020-10-13 | 何鑫 | A Chinese medicinal preparation for treating traumatic injury, and its preparation method |
Also Published As
| Publication number | Publication date |
|---|---|
| CN1055834C (en) | 2000-08-30 |
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Granted publication date: 20000830 Termination date: 20110218 |