CN108447373A - A kind of animal fears high experimental apparatus for testing and probably high test experiments method - Google Patents
A kind of animal fears high experimental apparatus for testing and probably high test experiments method Download PDFInfo
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- CN108447373A CN108447373A CN201810472408.7A CN201810472408A CN108447373A CN 108447373 A CN108447373 A CN 108447373A CN 201810472408 A CN201810472408 A CN 201810472408A CN 108447373 A CN108447373 A CN 108447373A
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Abstract
The present invention discloses a kind of animal and fears high experimental apparatus for testing and probably high test experiments method, is related to animal experiment technique field.The device includes for placing by the table top of experimental animal, supporting rack supporting bable tops, and table top is detachably fixed with supporting rack；Video camera, for shooting behavior of the record by experimental animal on table top；The height of supporting rack is adjustable.The device is versatile, can be tested suitable for different types of animal.The invention also discloses animals to fear high test experiments method.The experimental method is simple, and data are accurate, can obtain effectively evaluating parameter.
Description
Technical field
The present invention relates to animal experiment technique fields more particularly to a kind of animal to fear high experimental apparatus for testing and probably high test
Experimental method.
Background technology
In the research of mental disease, many scientific researches do not carry out directly on the person, but pass through animal
Model carries out.Therefore, the zoopery normal form of the specification of some international endorsements and mode are with regard to essential.And in animal behavior
Learn research in, probably high row be a critically important content.
In the prior art in probably high performance testing, a kind of method is that animal is forcibly placed on to length of side 5cm or so
A square plateau on, behavior of the observation animal in plateau, but this behaviouristics normal form lacks the ginseng of ocular and clear
Number is qualitative to carry out；Another method is that one is arranged in spacious environment with gradient, the irregular plateau that can be climbed, observation
The performance that animal climbs up, but the drawbacks of this method be its to the motor function of animal, explore and be intended to etc. all to require, but adopt
The result tested in this way is just related with many factors rather than just probably high level, and test result is not accurate enough.
Invention content
In view of the above-mentioned problems, the present invention proposes that a kind of animal fears high experimental apparatus for testing, the device is versatile, Neng Goushi
It is tested for different types of animal.
The present invention also proposes that a kind of animal fears high test experiments method, and the experimental method is simple, and data are accurate, can obtain
Effectively evaluating parameter.
The present invention uses following technical scheme：
A kind of animal fears high experimental apparatus for testing, including：For placing by the table top of experimental animal, supporting rack supporting table
Face,
Table top is detachably fixed with supporting rack；
Video camera, for shooting behavior of the record by experimental animal on table top；
The height of supporting rack is adjustable.
As a preferred embodiment of the present invention, plane where table top is provided with test zone, and test zone includes safety
Region, subsidiary risk region and danger zone；The safety zone that table top inside center position is formed, on table top other than safety zone
Part is subsidiary risk region, and the subregion other than plane upper table surface where table top forms danger zone.
As a preferred embodiment of the present invention, mesa boundaries shape and safety zone, subsidiary risk region and danger zone
Boundary shape it is identical.
As a preferred embodiment of the present invention, mesa boundaries shape is square, safety zone, subsidiary risk region and danger
The boundary shape in danger zone domain is square.
As a preferred embodiment of the present invention, the length of side of table top is twice of the outer boundary length of side of safety zone, table top
The length of side it is equal with the outer boundary length of side in subsidiary risk region, the outer boundary length of side of danger zone is twice of the table top length of side.
As a preferred embodiment of the present invention, supporting rack is tripod structure, and tripod structure includes more stabilizer blades, branch
Adjustable angle and/or leg length are adjustable between foot.
As a preferred embodiment of the present invention, it is detachably fixed by mounting bracket between table top and supporting rack.
As a preferred embodiment of the present invention, table top is nontransparent material, the color of table top and the hair by experimental animal
Color is different.
As a preferred embodiment of the present invention, when being rat by experimental animal, the height of supporting rack is 90cm-
The length of side of 110cm, table top are 40cm-60cm；When being mouse by experimental animal, the height of supporting rack is 50cm-70cm, table top
The length of side be 10cm-30cm.
As a preferred embodiment of the present invention, the material of supporting rack is metal, and mesa material is organic glass or PLA materials
Material.
A kind of animal fears high test experiments method, includes the following steps：
S1, the table top that animal is feared to high test experiments mark off the test zone of several different danger classes；
To be placed at the center of table top by experimental animal, start timing, video camera to by experimental animal in test zone
Interior movement is shot；
Record is entered time and the number of the test zone of different danger classes by laboratory animal head.
It is further comprising the steps of as a preferred embodiment of the present invention：
S2, when experiment reaches the predetermined time, will be taken away by experimental animal, to table top disinfection, taste removal；
S3, it removes one and is tested by experimental animal, repeat step S1 to step S2；
S4, step S1 to step S3 is repeated, obtains sufficient amount of experimental data.
It is further comprising the steps of before step S1 as a preferred embodiment of the present invention：
S0, according to by experimental animal type adjust table top height；Table top is selected according to by the type of experimental animal
Size.
Beneficial effects of the present invention are：
(1) a kind of animal proposed by the present invention fears high experimental apparatus for testing, can be with by the way that test zone is arranged on table top
Activity condition of the animal in test zone is shot by video camera, to obtain suitable data；By by table top and supporting rack
Be set as being detachably fixed and the height of supporting rack be set as adjustable so that experimental provision can according to animal species it is different into
Row adjustment, it is versatile, it can be tested suitable for different types of animal.
(2) a kind of animal proposed by the present invention fears high test experiments method, using above-mentioned experimental provision, and in an animal
It carries out disinfection to table top after the completion of experiment, taste removal, eliminates influence of the other factors to experiment accuracy so that experimental data is more
Accurately.
Description of the drawings
Fig. 1 is the structural schematic diagram that the animal that the embodiment of the present invention one provides fears high experimental apparatus for testing；
Fig. 2 is the schematic diagram for the test zone that the embodiment of the present invention one provides.
In figure：
1, table top；11, safety zone；12, subsidiary risk region；
2, danger zone；
3, supporting rack；31, stabilizer blade；
4, video camera；
5, mounting bracket.
Specific implementation mode
The present invention is described in further detail with reference to the accompanying drawings and examples.It is understood that this place is retouched
The specific embodiment stated is used only for explaining the present invention rather than limitation of the invention.It also should be noted that in order to just
Only the parts related to the present invention are shown in description, attached drawing rather than entire infrastructure.
Embodiment one：
Fig. 1 is the structural schematic diagram that the animal that the embodiment of the present invention one provides fears high experimental apparatus for testing, as shown in Figure 1,
It includes table top 1, supporting rack 3 and video camera 4 that animal, which fears high experimental apparatus for testing mainly, wherein table top 1 is dynamic by experiment for placing
The height of object, supporting rack 3 is adjustable, and supporting rack 3 is used to support table top 1, i.e. table top 1 is raised certain height by supporting rack 3, by reality
Testing animal can feel that this height, 1 top of table top are provided with video camera 4, will be put by experimental animal on the playing surface 1,
Video camera 4 is used to shoot behavior of the record by experimental animal on the playing surface 1 towards table top 1, is analyzed on this basis, energy
Whether enough analyses are that probably high row is by experimental animal.
Fig. 2 is the schematic diagram for the test zone that the embodiment of the present invention one provides, as shown in Fig. 2, 1 place plane setting of table top
It includes safety zone 11, subsidiary risk region 12 and danger zone 2 to have test zone, test zone.Wherein, test zone is included in
1 inside center position of table top forms safety zone 11, on table top 1 safety zone 11 using outer portion as subsidiary risk region 12, and
Subregion other than 1 place plane of table top forms danger zone 2.That is, safety zone 11 and subsidiary risk region 12 collectively constitute
1 structure of table top, which is by experimental animal, to be also entity structure with movable region；And danger zone 2 is that 1 place of table top is flat
Subregion other than face, be by experimental animal cannot movable region, be non-physical structure, by experimental animal lean out head from
Subsidiary risk region 12 to danger zone 2 be can be with direct feeling to table top 1 apart from ground height.In actual use process
In, 1 center of table top can be placed in by experimental animal, ground is can't see in 11 activity to the animal in safety zone, is peace
Complete；When animal activity is to subsidiary risk region 12, and head is leant out into danger zone 2, can feel dangerous, if animal is to height
Degree generate it is frightened if, head dare not can again be insinuated into danger zone 2, that is, into danger zone 2 time and
Number is significantly reduced；In addition if animal generates fear to height, body can be forced down and crept, it can be from platform
1 top of face is provided with video camera 4 and is recorded.
Further, table top 1 is nontransparent material, and this set not can be appreciated that in safety zone 11 by experimental animal
The bottom surface of lower section, also with regard to the danger of imperceptible height.Organic glass or PLA material, table top 1 may be used in the material of table top 1
Color it is different from by the hair color of experimental animal, and non-black, non-white, this set video camera 4 record on table top 1 to move
The action of object is more clear.Further, 1 boundary shape of table top and safety zone 11, subsidiary risk region 12 and danger zone 2
Boundary shape is identical, and this set is conducive to that movable probability is identical in test zone by experimental animal, advantageously ensures that
The accuracy of experimental data.Preferably, by taking the test zone in Fig. 2 as an example, 1 boundary shape of table top is square, safety zone
11, the outer boundary shape of subsidiary risk region 12 and danger zone 2 is square.
As shown in Figure 1, supporting rack 3 can be tripod structure, tripod structure includes more stabilizer blades 31, can be by changing
The angle become between multiple stabilizer blades 31 realizes that supporting rack 3 is adjustable in the height direction；It is adjustable stabilizer blade 31 can also to be arranged to length
Structure；The angle between the length of stabilizer blade 31 and multiple stabilizer blades 31 can also be adjusted.It is contemplated that ground is, the present invention is simultaneously unlimited
The structure type of supporting rack 3 processed is within the scope of the invention as long as can realize that supporting rack 3 is adjustable in the height direction.
Further, the material of supporting rack 3 is metal, advantageously ensures that the structural stability of supporting rack 3.Between table top 1 and supporting rack 3
It is detachably fixed by mounting bracket 5, mounting bracket 5 can be mutually matched protrusion and groove, can be sliding block and sliding rail, can be with
For the threaded hole being correspondingly arranged, the concrete structure of mounting bracket 5 can not be limited, as long as platform can be realized by bolt tightly
It is detachably fixed, is within the scope of the invention by mounting bracket 5 between face 1 and supporting rack 3.
The size of table top 1 can be selected according to by the type of experimental animal, and the height of supporting rack 3 can be according to dynamic by experiment
The type of object is adjusted.Preferably, the length of side of table top 1 is twice of the outer boundary length of side of safety zone 11, the length of side of table top 1
Equal with the outer boundary length of side in subsidiary risk region 12, the outer boundary length of side of danger zone 2 is twice of the length of side of table top 1.With Fig. 2
Can be 90cm- by the height of supporting rack 3 if being rat by experimental animal for middle mesa boundaries shape is square
The length of side of 110cm, preferably 100cm, table top 1 are 40cm-60cm, preferably 50cm.It, can be with if being mouse by experimental animal
It is 50cm-70cm by the height of supporting rack 3, the length of side of preferably 60cm, table top 1 are 10cm-30cm, preferably 20cm.According to
By the difference of experimental animal, the height of supporting rack 3 is adjusted, chooses 1 size of table top, due to being between table top 1 and supporting rack 3
It is detachably fixed, selected table top 1 can be mounted on the supporting rack 3 adjusted by mounting bracket 5.
Embodiment two：
The embodiment of the present invention two proposes a kind of animal and fears high test experiments method, with rat in rodent and small
It is introduced for mouse, which mainly includes the following steps that：
By taking mouse as an example, the first step is tested：
Mouse is placed at the center of table top, the table top that animal is feared to high test experiments marks off several different danger
The test zone of grade, mouse freely activity, starts timing.Video camera by movement of the experimental animal in test zone to being carried out
Shooting, and record data.
Test second step：
Reaching the predetermined time, the predetermined time in the present embodiment is 10min, i.e. mouse looses 10min on the playing surface 1,
Mouse is taken away.Then table top will be sterilized, taste removal with 75% alcohol wipe, dispels a mouse in the present embodiment
Taste, avoid interference of the other factors to experimental result.
Test third step：
It removes a mouse to be tested, experimental procedure repeats the above steps.
Test the 4th step：
One is repeated the above steps to step 3, sufficient amount of experimental data is obtained, quilt is analyzed by specific software
Laboratory animal head enters time and the number of test zone.In the present embodiment, animal is tracked using anymaze softwares
Head, analytical effect more preferably, precision higher.
The experimental method is simple, and data are accurate, can obtain effectively evaluating parameter.
Embodiment three：
Embodiment three is identical as the experimental method main body of embodiment two, unlike the method for embodiment two, embodiment
Three preferably use the animal in embodiment one to fear high experimental apparatus for testing, are carried out by taking rat and mouse in rodent as an example
It introduces, is mainly included the following steps that with the method difference of embodiment two：
Preparation before experiment includes two steps, respectively adjusts supporting rack 3 according to by the type of experimental animal
Highly, according to the size for being selected table top 1 by the type of experimental animal.By taking mesa boundaries shape is square in Fig. 2 as an example, if
It is rat by experimental animal, can is 90cm-110cm by the height of supporting rack 3, the length of side of preferably 100cm, table top 1 are
40cm-60cm, preferably 50cm.Can be 50cm-70cm by the height of supporting rack 3, preferably if being mouse by experimental animal
The length of side for 60cm, table top 1 is 10cm-30cm, preferably 20cm.Preferably, the length of side of table top 1 is the outside of safety zone 11
The length of side of twice of boundary's length of side, table top 1 is equal with the outer boundary length of side in subsidiary risk region 12, and the boundary edge of danger zone 2 is a length of
Twice of the length of side of table top 1.According to by the difference of experimental animal, the height of supporting rack 3 is adjusted, chooses 1 size of table top, by
It is detachably fixed by mounting bracket 5 between table top 1 and supporting rack 3, selected table top 1 can be mounted in the branch adjusted
On support 3, video camera 4 is regulated.The Preparatory work of experiment stage finishes.
Note that above are only presently preferred embodiments of the present invention and institute's application technology principle.It will be appreciated by those skilled in the art that
The present invention is not limited to specific embodiments here, can carry out for a person skilled in the art it is various it is apparent variation, again
Adjustment and replacement are without departing from protection scope of the present invention.Therefore, although by above example to the present invention carried out compared with
For detailed description, but the present invention is not limited only to above example, without departing from the inventive concept, can be with
Including other more equivalent embodiments, and the scope of the present invention is determined by scope of the appended claims.
Claims (13)
1. a kind of animal fears high experimental apparatus for testing, including：For placing by the table top (1) of experimental animal, supporting rack (3) support
The table top (1), which is characterized in that
The table top (1) is detachably fixed with support frame as described above (3)；
Video camera (4), for shooting behavior of the record by experimental animal on the table top (1)；
The height of support frame as described above (3) is adjustable.
2. animal according to claim 1 fears high experimental apparatus for testing, which is characterized in that plane where the table top (1)
It is provided with test zone, the test zone includes safety zone (11), subsidiary risk region (12) and danger zone (2)；It is described
Table top (1) inside center position forms the safety zone (11), the safety zone (11) with outside on the table top (1)
Be divided into the subsidiary risk region (12), the table top (1) subregion other than the table top (1) described in the plane formed it is described
Danger zone (2).
3. animal according to claim 2 fears high experimental apparatus for testing, which is characterized in that the shape of the table top (1) with
The safety zone (11), subsidiary risk region (12) are identical with the outer boundary shape of danger zone (2).
4. animal according to claim 3 fears high experimental apparatus for testing, which is characterized in that the shape of the table top (1) is
The outer boundary shape of square, the safety zone (11), subsidiary risk region (12) and danger zone (2) is square.
5. animal according to claim 4 fears high experimental apparatus for testing, which is characterized in that the length of side of the table top (1) is
Twice of the outer boundary length of side of the safety zone (11), the length of side of the table top (1) are outer with the subsidiary risk region (12)
Boundary edge length is equal, and the outer boundary length of side of the danger zone (2) is twice of the table top (1) length of side.
6. animal according to claim 1 fears high experimental apparatus for testing, which is characterized in that support frame as described above (3) is three feet
Frame structure, the tripod structure include more stabilizer blades (31), adjustable angle and/or stabilizer blade (31) length between the stabilizer blade (31)
It is adjustable.
7. animal according to claim 1 fears high experimental apparatus for testing, which is characterized in that the table top (1) and the branch
It is detachably fixed by mounting bracket (5) between support (3).
8. animal according to claim 7 fears high experimental apparatus for testing, which is characterized in that the table top (1) is nontransparent
The color of material, the table top (1) is different from by the hair color of experimental animal.
9. animal according to claim 5 fears high experimental apparatus for testing, which is characterized in that when it is described by experimental animal be big
When mouse, the height of support frame as described above (3) is 90cm-110cm, and table top (1) length of side is 40cm-60cm；It is tested when described
When animal is mouse, the height of support frame as described above (3) is 50cm-70cm, and table top (1) length of side is 10cm-30cm.
10. fearing high experimental apparatus for testing according to animal described in any one of claim 1-9, which is characterized in that the support
The material of frame (3) is metal, and table top (1) material is organic glass or PLA material.
11. a kind of animal fears high test experiments method, which is characterized in that include the following steps：
S1, the table top that animal is feared to high test experiments mark off the test zone of several different danger classes；
To be placed at the center of table top by experimental animal, start timing, video camera to by experimental animal in test zone
Movement is shot；
Record is entered time and the number of the test zone of different danger classes by laboratory animal head.
12. animal according to claim 11 fears high test experiments method, which is characterized in that further include after step S1 with
Lower step：
S2, when experiment reaches the predetermined time, will be taken away by experimental animal, to table top disinfection, taste removal；
S3, it removes one and is tested by experimental animal, repeat step S1 to step S2；
S4, step S1 to step S3 is repeated, obtains sufficient amount of experimental data.
13. animal according to claim 11 fears high test experiments method, which is characterized in that before step S1, also wrap
Include following steps：
S0, according to by experimental animal type adjust table top height, select the table top according to by the type of experimental animal
Size.
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810472408.7A CN108447373A (en) | 2018-05-17 | 2018-05-17 | A kind of animal fears high experimental apparatus for testing and probably high test experiments method |
| PCT/CN2018/102233 WO2019218519A1 (en) | 2018-05-17 | 2018-08-24 | Animal height fear test experimental device and height fear test experimental method |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810472408.7A CN108447373A (en) | 2018-05-17 | 2018-05-17 | A kind of animal fears high experimental apparatus for testing and probably high test experiments method |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN108447373A true CN108447373A (en) | 2018-08-24 |
Family
ID=63204503
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201810472408.7A Pending CN108447373A (en) | 2018-05-17 | 2018-05-17 | A kind of animal fears high experimental apparatus for testing and probably high test experiments method |
Country Status (2)
| Country | Link |
|---|---|
| CN (1) | CN108447373A (en) |
| WO (1) | WO2019218519A1 (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110840410A (en) * | 2019-12-05 | 2020-02-28 | 中国科学院深圳先进技术研究院 | Animal passive terrorism high behavior testing device |
| CN113575445A (en) * | 2021-08-12 | 2021-11-02 | 中国科学技术大学 | Behaviourological device for testing negative emotion |
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| DE19946126A1 (en) * | 1999-09-20 | 2001-03-22 | Rech Oliver | Acrophobia system comprises narrow running surface anchored at ends at height so safety-harnessed person can walk along as linked to rollers riding overhead steel rope. |
| CN104116515A (en) * | 2014-07-10 | 2014-10-29 | 中国人民解放军军事医学科学院基础医学研究所 | Elevated platform for detecting animal anxiety and application method thereof |
| CN205054165U (en) * | 2015-07-24 | 2016-03-02 | 上海市同济医院 | Motion of multi -functional mouse and sensory nerve performance testing appearance |
| CN106448405A (en) * | 2016-11-18 | 2017-02-22 | 中国科学院深圳先进技术研究院 | Rodent animal height fear test experiment device and experiment method |
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2018
- 2018-05-17 CN CN201810472408.7A patent/CN108447373A/en active Pending
- 2018-08-24 WO PCT/CN2018/102233 patent/WO2019218519A1/en active Application Filing
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19946126A1 (en) * | 1999-09-20 | 2001-03-22 | Rech Oliver | Acrophobia system comprises narrow running surface anchored at ends at height so safety-harnessed person can walk along as linked to rollers riding overhead steel rope. |
| CN104116515A (en) * | 2014-07-10 | 2014-10-29 | 中国人民解放军军事医学科学院基础医学研究所 | Elevated platform for detecting animal anxiety and application method thereof |
| CN205054165U (en) * | 2015-07-24 | 2016-03-02 | 上海市同济医院 | Motion of multi -functional mouse and sensory nerve performance testing appearance |
| CN106448405A (en) * | 2016-11-18 | 2017-02-22 | 中国科学院深圳先进技术研究院 | Rodent animal height fear test experiment device and experiment method |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110840410A (en) * | 2019-12-05 | 2020-02-28 | 中国科学院深圳先进技术研究院 | Animal passive terrorism high behavior testing device |
| WO2021109186A1 (en) * | 2019-12-05 | 2021-06-10 | 中国科学院深圳先进技术研究院 | Animal passive fear-of-heights behavior test device |
| CN110840410B (en) * | 2019-12-05 | 2022-02-15 | 中国科学院深圳先进技术研究院 | Animal passive terrorism high behavior testing device |
| CN113575445A (en) * | 2021-08-12 | 2021-11-02 | 中国科学技术大学 | Behaviourological device for testing negative emotion |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2019218519A1 (en) | 2019-11-21 |
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