CN108431818B - 检测闪光和辉光反应中的分析物 - Google Patents

检测闪光和辉光反应中的分析物 Download PDF

Info

Publication number
CN108431818B
CN108431818B CN201680077143.XA CN201680077143A CN108431818B CN 108431818 B CN108431818 B CN 108431818B CN 201680077143 A CN201680077143 A CN 201680077143A CN 108431818 B CN108431818 B CN 108431818B
Authority
CN
China
Prior art keywords
signal
data points
accuracy
background
sample
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CN201680077143.XA
Other languages
English (en)
Chinese (zh)
Other versions
CN108431818A (zh
Inventor
D.A.雷
P.海特
M.沙尔马
N.赖尼希
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of CN108431818A publication Critical patent/CN108431818A/zh
Application granted granted Critical
Publication of CN108431818B publication Critical patent/CN108431818B/zh
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C12Q1/04—Determining presence or kind of microorganism; Use of selective media for testing antibiotics or bacteriocides; Compositions containing a chemical indicator therefor
    • C12Q1/14—Streptococcus; Staphylococcus
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16C—COMPUTATIONAL CHEMISTRY; CHEMOINFORMATICS; COMPUTATIONAL MATERIALS SCIENCE
    • G16C20/00—Chemoinformatics, i.e. ICT specially adapted for the handling of physicochemical or structural data of chemical particles, elements, compounds or mixtures
    • G16C20/70—Machine learning, data mining or chemometrics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Theoretical Computer Science (AREA)
  • Databases & Information Systems (AREA)
  • Software Systems (AREA)
  • Medical Informatics (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Computing Systems (AREA)
  • Evolutionary Computation (AREA)
  • Artificial Intelligence (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Data Mining & Analysis (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Immunology (AREA)
  • Toxicology (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Management, Administration, Business Operations System, And Electronic Commerce (AREA)
CN201680077143.XA 2015-12-31 2016-12-29 检测闪光和辉光反应中的分析物 Active CN108431818B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562273845P 2015-12-31 2015-12-31
US62/273845 2015-12-31
PCT/EP2016/082880 WO2017114925A1 (en) 2015-12-31 2016-12-29 Detecting an analyte in a flash and glow reaction

Publications (2)

Publication Number Publication Date
CN108431818A CN108431818A (zh) 2018-08-21
CN108431818B true CN108431818B (zh) 2022-03-25

Family

ID=57868203

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201680077143.XA Active CN108431818B (zh) 2015-12-31 2016-12-29 检测闪光和辉光反应中的分析物

Country Status (5)

Country Link
US (1) US10718003B2 (https=)
EP (1) EP3398100B1 (https=)
JP (1) JP7085480B2 (https=)
CN (1) CN108431818B (https=)
WO (1) WO2017114925A1 (https=)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11149319B2 (en) * 2016-12-20 2021-10-19 Roche Molecular Systems, Inc. Systems and methods for detecting cells using engineered transduction particles
EP3821249B1 (en) * 2018-07-13 2022-06-29 3M Innovative Properties Company Specific binding chemiluminescent assay
CN111461243B (zh) * 2020-04-08 2023-06-20 中国医学科学院肿瘤医院 分类方法、装置、电子设备及计算机可读存储介质
CN114529755B (zh) * 2022-01-24 2024-04-09 西北大学 用于测试甲状腺乳头状癌的系统
TR2023001883A1 (tr) * 2023-02-20 2024-08-21 Ostim Teknik Ueniversitesi Metsisilin Dirençli Stafilococcus Aureus Enfeksiyonu İçin Erken Tespit Sistemi

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6512936B1 (en) * 1999-07-22 2003-01-28 Sensys Medical, Inc. Multi-tier method of classifying sample spectra for non-invasive blood analyte prediction

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5329461A (en) * 1992-07-23 1994-07-12 Acrogen, Inc. Digital analyte detection system
WO2005115737A2 (en) 2004-03-22 2005-12-08 Quantaspec Inc. System and method for detecting and identifying an analyte
US7587279B2 (en) 2004-07-06 2009-09-08 Genomic Health Method for quantitative PCR data analysis system (QDAS)
EP1798542A1 (en) 2005-12-19 2007-06-20 Roche Diagnostics GmbH Analytical method and instrument
CA2684311A1 (en) 2007-04-18 2008-10-30 Cornell University Microorganism detection method and apparatus
US7983852B2 (en) 2008-10-21 2011-07-19 Thermo Finnigan Llc Methods of automated spectral peak detection and quantification without user input
US8497086B2 (en) 2009-08-13 2013-07-30 Biomereux Reaction medium for methicillin-resistant Staphylococcus aureus (MRSA) bacteria
AU2013225728B2 (en) * 2012-03-01 2018-07-26 Ortho-Clinical Diagnostics, Inc. Interactive test device and apparatus with timing mechanism
CN102955030A (zh) * 2012-06-11 2013-03-06 郑州安图绿科生物工程有限公司 检测自身免疫性肝病相关抗体ana的试剂盒及其检测方法
CN104870652A (zh) * 2012-10-05 2015-08-26 加州理工学院 用于微流体成像和分析的方法和系统
KR102127358B1 (ko) 2013-03-13 2020-06-29 지니위브 바이오사이언시스, 인코포레이티드 비-복제 형질도입 입자 및 형질도입 입자-기반 리포터 시스템
US9481903B2 (en) 2013-03-13 2016-11-01 Roche Molecular Systems, Inc. Systems and methods for detection of cells using engineered transduction particles
US9540675B2 (en) 2013-10-29 2017-01-10 GeneWeave Biosciences, Inc. Reagent cartridge and methods for detection of cells

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6512936B1 (en) * 1999-07-22 2003-01-28 Sensys Medical, Inc. Multi-tier method of classifying sample spectra for non-invasive blood analyte prediction

Also Published As

Publication number Publication date
JP2019507863A (ja) 2019-03-22
US10718003B2 (en) 2020-07-21
JP7085480B2 (ja) 2022-06-16
CN108431818A (zh) 2018-08-21
EP3398100B1 (en) 2023-08-30
US20170191111A1 (en) 2017-07-06
WO2017114925A1 (en) 2017-07-06
EP3398100A1 (en) 2018-11-07

Similar Documents

Publication Publication Date Title
CN108431818B (zh) 检测闪光和辉光反应中的分析物
Bacher et al. SCnorm: robust normalization of single-cell RNA-seq data
Huang et al. Detection of carbapenem-resistant Klebsiella pneumoniae on the basis of matrix-assisted laser desorption ionization time-of-flight mass spectrometry by using supervised machine learning approach
Williams et al. Identification of neutral tumor evolution across cancer types
Peter et al. Distinguishing between selective sweeps from standing variation and from a de novo mutation
US11995568B2 (en) Identification and prediction of metabolic pathways from correlation-based metabolite networks
WO2016018481A2 (en) Network based stratification of tumor mutations
Ståhlberg et al. The added value of single-cell gene expression profiling
JP7748360B2 (ja) 検体レベルの適応正規化のための方法、装置、及びコンピュータ読み取り可能な媒体
Michaut et al. Multiple genetic interaction experiments provide complementary information useful for gene function prediction
EP3959331A1 (en) Multipore determination of fractional abundance of polynucleotide sequences in a sample
Briscoe et al. Evaluating supervised and unsupervised background noise correction in human gut microbiome data
Markitsis et al. A censored beta mixture model for the estimation of the proportion of non-differentially expressed genes
Lee et al. Detection of correlated hidden factors from single cell transcriptomes using Iteratively Adjusted-SVA (IA-SVA)
US20160314244A1 (en) Systems and methods for predicting a smoking status of an individual
US20240363197A1 (en) Methods for characterizing infections and methods for developing tests for the same
Jiang et al. PRPS-ST: A protocol-agnostic self-training method for gene expression–based classification of blood cancers
Nourmohammad et al. Formation of regulatory modules by local sequence duplication
US11149319B2 (en) Systems and methods for detecting cells using engineered transduction particles
US20120288849A1 (en) Method and system for robust and sensitive analysis of bead-based assays
Mestres et al. Adjusting for systematic technical biases in risk assessment of gene signatures in transcriptomic cancer cohorts
Xu et al. Single cell metabolic phenome and genome via the ramanome technology platform: Precision medicine of infectious diseases at the ultimate precision?
Narayanan et al. Robust inference of cell-to-cell expression variations from single-and k-cell profiling
Sun et al. Evaluating Cross-Platform Normalization Methods for Integrated Microarray and RNA-seq Data Analysis
Shu et al. Mergeomics: integration of diverse genomics resources to identify pathogenic perturbations to biological systems

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
GR01 Patent grant
GR01 Patent grant