CN108421570B

CN108421570B - Box forming device and box forming method for pipette tips

Info

Publication number: CN108421570B
Application number: CN201710081521.8A
Authority: CN
Inventors: 任娜娜; 马强; 樊德华; 田海芹; 冯菊芳; 朱爽; 韩波; 张殿伟; 孙冬胜
Original assignee: China Petroleum and Chemical Corp; Sinopec Exploration and Production Research Institute
Current assignee: China Petroleum and Chemical Corp; Sinopec Exploration and Production Research Institute
Priority date: 2017-02-15
Filing date: 2017-02-15
Publication date: 2021-05-14
Anticipated expiration: 2037-02-15
Also published as: CN108421570A

Abstract

The invention provides a box forming device and a box forming method for a pipette head, which comprise the following steps: the liquid transfer gun comprises a box body, a barrier plate and at least one through hole, wherein the box body is arranged above a liquid transfer gun box, the barrier plate is formed by at least one strip-shaped partition strip, any two adjacent partition strips are arranged in parallel, the distance between the barrier plate and the liquid transfer gun box is greater than or equal to the length of the liquid transfer gun head, the through holes are integrally formed in the end parts of the two adjacent partition strips, and the number of the through holes is equal to the number of gaps; the shifting piece is composed of a handle and a thin plate which is perpendicular to the handle and has the length equal to the width of the box body; and the pipette tip hole is used for receiving the pipette tip passing through the pipette tip hole. The device and the method provided by the invention have the advantages of simple design, low cost and convenience in operation, and can realize the quick arrangement of the pipette heads into boxes and improve the working efficiency.

Description

Box forming device and box forming method for pipette tips

Technical Field

The application relates to the technical field of machinery, in particular to a pipette tip boxing device and a boxing method.

Background

The pipette is a liquid taking tool commonly used in laboratories and is used for accurately taking liquid; the pipette head is used as a matching device of the pipette, and is required to be inserted into the pipette head box in a non-use state according to the operation rules. At present, the pipette head used in a biological laboratory is made of plastic and has a cone structure, the pipette head has different specifications, the longest pipette head is 80mm, the shortest pipette head is 40mm, and the diameter of the large end is changed along with the length of the pipette head, generally from 4mm to 10 mm. Fig. 1 is a schematic structural diagram of a pipette gun box 7, and as shown in fig. 1, a plurality of gun head holes 8 into which pipette gun heads can be inserted are arranged in a row in the pipette gun box 7, and the pipette gun heads are inserted into the gun head holes 8 in a production or non-use state.

Disclosure of Invention

The application provides a pipetting gun head box forming device and a pipetting gun head box forming method, the design is simple, the cost is low, the use is convenient, the device is suitable for being used in a laboratory, the pipetting gun heads can be rapidly arranged into boxes, and the working efficiency is improved.

This liquid-transfering gun rifle head becomes box-packed putting is arranged in inserting the rifle head hole of liquid-transfering gun rifle head to liquid-transfering gun rifle box, includes: the liquid transfer gun comprises a box body, a plurality of partition strips and a plurality of through holes, wherein the box body is arranged above a liquid transfer gun box and used for containing liquid transfer gun heads to be boxed, a fence plate and at least one through hole through which the liquid transfer gun heads can pass are arranged in the box body, the fence plate is composed of at least one rectangular partition strip, any two adjacent partition strips are arranged in parallel and at equal intervals so that the liquid transfer gun heads can be clamped between the gaps of the two adjacent partition strips in an upright state, the distance between the fence plate and the liquid transfer gun box is greater than or equal to the length of the liquid transfer gun heads, the through holes are integrally arranged at the end parts of the two adjacent partition strips, and the number of the through holes is equal to the number of; the shifting sheet is composed of a handle at the end part and a thin plate with the length equal to the width of the box body and is used for guiding the pipette head in the vertical state to move to the through hole along the gap of the partition strip so as to enable the pipette head to be inserted into the pipette head hole from the through hole; and the pipette tip hole is used for receiving the pipette tip passing through the through hole.

In one possible implementation of the present application, the width of the gap is equal to the maximum diameter of the pipette tip.

In one possible implementation manner of the application, the length of the baffle parallel to the moving direction of the pipette head in the box body is smaller than the length of the baffle perpendicular to the moving direction of the pipette head.

In one possible implementation manner of the present application, the box further includes: and the length of the bottom plate is less than or equal to that of the partition strip, and the bottom plate does not cover the through hole.

In one possible implementation of the present application, the passage hole is semicircular, and the diameter of the semicircle is larger than the maximum diameter of the pipette tip.

In one possible implementation of the present application, the passage hole is rectangular, the width of the rectangle being greater than the maximum diameter of the pipette tip.

In one possible implementation of the present application, the device is made of a polyethylene material that is resistant to high temperature sterilization.

The box forming method comprises the following steps: the method comprises the following steps: aligning the at least one through hole with one row of gun head holes of the pipette gun box; step two: pouring a plurality of pipette heads of the pipette into the fence plate; step three: slightly shaking the box body to enable the gun heads of the liquid-transfering guns to be clamped between the gaps in an upright state; step four: guiding a row of pipette tips to move along the gap to the through hole by using a plectrum so that the pipette tips are inserted into the tip holes from the through hole; step five: and repeating the first step to the fourth step to finish the box forming process of the plurality of pipette tips of the pipette.

In one possible implementation of the present application, in step one, at least one of the through holes is aligned with one of the rows of gun head holes of the pipette gun magazine by sliding the magazine.

By adopting the box forming device and the box forming method for the pipette tips provided by the embodiment of the invention, the structure and the operation are simple, the pipette tips can be quickly arranged into boxes, the working efficiency is improved, and the labor cost is reduced; meanwhile, the device is low in cost and easy to clean, the contact frequency of the gun heads with parts and personnel is reduced in the sequencing process, the pollution risk is greatly reduced, and the experiment accuracy is improved.

Additional features and advantages of the invention will be set forth in the description which follows, and in part will be obvious from the description, or may be learned by practice of the invention. The objectives and other advantages of the invention will be realized and attained by the structure particularly pointed out in the written description and claims hereof as well as the appended drawings.

Drawings

In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the following briefly introduces the drawings required in the description of the embodiments or the prior art:

fig. 1 is a schematic structural view of a pipette magazine 7.

FIG. 2 is a schematic structural diagram of a pipette tip boxing device according to an embodiment of the invention.

Fig. 3 is a schematic structural diagram of the pick 9 according to the embodiment of the present invention.

In the drawings, like parts are provided with like reference numerals. The drawings are not to scale.

Detailed Description

The invention will be further explained with reference to the drawings.

The following detailed description of the embodiments of the present invention will be provided with reference to the drawings and examples, so that how to apply the technical means to solve the technical problems and achieve the technical effects can be fully understood and implemented. The particulars shown herein are by way of example and for purposes of illustrative discussion of the embodiments of the present invention only and are presented in the cause of providing what is believed to be the most useful and readily understood description of the principles and conceptual aspects of the present invention. In this regard, no attempt is made to show structural details of the invention in more detail than is necessary for a fundamental understanding of the invention, the description taken with the drawings making apparent to those skilled in the art how the several forms of the invention may be embodied in practice.

Chinese patent application No. CN105460273A (application No. CN201510959640.X) discloses an automatic boxing device for pipette tips, which comprises a funnel capable of containing pipette tips, wherein the bottom of the funnel is provided with a groove capable of sending out the pipette tips, a separator capable of separating the pipette tips of adjacent pipette tips from aligning to a pipette tip hole 8 is arranged in the groove, the separator comprises a separation needle capable of being inserted into the pipette tips, the separation needle is inserted into the pipette tips, and the separator drives the separation needle to move so that the pipette tips are inserted into the pipette tip hole 8 on a pipette gun box 7. Although the boxing device can be inserted into the gun heads through the separation needles of the separators, the gun heads are transported more stably and are boxed accurately, the boxing device is complex in structure and more in parts, so that the boxing device is high in cost and is not suitable for laboratories; in addition, the box forming device is not easy to clean, and the gun heads are contacted with excessive parts of the instruments in the sequencing process, so that the risk of pollution is increased.

FIG. 2 is a schematic structural diagram of a pipette tip boxing device according to an embodiment of the invention. As shown in fig. 2, the pipette tip boxing apparatus can be used for inserting the pipette tips into the tip holes 8 of the pipette tip box 7, and comprises:

the liquid-transfering gun comprises a box body 1, a plurality of through holes 2 and a plurality of barrier strips 3, wherein the box body 1 is arranged above a liquid-transfering gun box 7 and used for containing liquid-transfering gun heads to be boxed, a barrier plate and at least one through hole 6 which can enable the liquid-transfering gun heads to pass through are arranged in the box body 1, the barrier plate is composed of at least one rectangular barrier strip 3, any two adjacent barrier strips 3 are arranged in parallel so that the liquid-transfering gun heads can be clamped between the gaps 2 of the two adjacent barrier strips 3 in an upright state, the distance between the barrier plate and the liquid-transfering gun box 7 is larger than or equal to the length of the liquid-transfering gun heads, the through holes 6 are integrally arranged at the end parts of the two adjacent barrier; the shifting sheet 9 consists of a handle 5 at the end part and a thin plate 4 with the length equal to the width of the box body 1 and is used for guiding the pipette tip in an upright state to move to the through hole 6 along the gap 2 of the partition strip 3 so as to insert the pipette tip into the pipette tip hole 8 from the through hole 6; and the pipette gun box 7 is arranged below the box body 1, and a gun head hole 8 is used for receiving the pipette gun head passing through the passage 6.

According to the box forming device for the pipette heads of the pipette, provided by the embodiment of the invention, the quick box forming of the pipette heads of the pipette can be realized, the working efficiency is improved, meanwhile, the device is simple in structure, lower in cost and easy to clean, the contact frequency of the pipette heads with parts and personnel is reduced in the sequencing process, the pollution risk is greatly reduced, and the experiment accuracy is improved.

It will be appreciated that in order to avoid dropping and thus contamination of the pipette tips in an upright position, the number of passage holes 6 in the pipetting gun tip magazine 7 should be less than or equal to the number of pipette tip holes 8 in each row so that pipette tips passing through each passage hole 6 can be inserted into aligned tip holes 8.

The width of the gap 2 between adjacent partition strips 3 on the barrier plate can be different according to the size of the pipette tip to be boxed, wherein the barrier plate in the box body 1 can be replaced according to different use requirements, and the size of the corresponding through hole 6 can be changed correspondingly.

Preferably, any two adjacent partition strips 3 in at least one partition strip 3 in the fence plate are equidistantly arranged in parallel, so that the tips of the liquid-transfering guns in the same batch can be completely clamped, and the box forming efficiency is improved. It should be understood that the width of the gap 2 between any two parallel partition bars 3 in the same fence plate can be the same or different, that is, the gap 2 with various width specifications can exist in the same fence plate, and the size of the through hole 6 in the box body 1 also has various specifications correspondingly, so that the liquid-transfering gun head to be boxed can be ensured to be clamped between the gaps 2 in an upright state, which is within the protection scope of the invention.

More preferably, the width of the gap 2 is slightly smaller than the maximum diameter of the pipette tip, that is, the position of the maximum diameter of the pipette tip is just clamped between the gap 2, and the pipette tip is almost completely positioned below the blocking strip 3 except the thickest part, so that the stability of the pipette tip in the vertical state between the gap 2 can be ensured, and the box forming efficiency is improved.

It will be appreciated that the number of septa 3 in the barrier and the width of the gap 2 will also depend on the number of gun head holes 8 in the pipette box 7 and the distance between the two holes.

The two ends of each passing hole 6 are integrally arranged with the two corresponding adjacent partition strips 3, that is, each partition strip 3 is connected with the end of the two adjacent passing holes 6, it should be understood that the passing holes 6 may be made of the same material as the partition strips 3 or different materials, the thickness of the passing holes 6 may be equal to or different from the thickness of the partition strips 3, and the invention is not limited herein.

Preferably, in the pipette tip boxing device of the present invention, the box body 1 may further include a bottom plate disposed at the bottom of the box body 1, which may protect the pipette tip from external contamination. It will be understood that the length of this bottom plate should be less than or equal to the same length of the upper partition strip 3 and that the bottom plate cannot cover the passage hole 6, preventing the lance tip from passing through the passage hole 6.

Preferably, the through hole 6 is in a semicircular shape, two ends of the semicircular shape are integrally connected with two adjacent partition strips 3, and the diameter of the semicircular shape is larger than the maximum diameter of the head of the liquid-transfering gun so as to ensure that the head can pass through the through hole 6;

the passage hole 6 is preferably rectangular, the two ends of which are integrally connected to two adjacent partition strips 3, the width of the rectangle being greater than the diameter of the tip of the pipetting gun to ensure that the tip can pass through the passage hole 6.

In the present invention, the shape of the passage hole 6 may also have various forms, such as a semi-oval shape, a square shape, etc., and it is within the scope of the present invention that the passage hole 6 can be integrally connected with the fence plate and sized to allow the tip end to pass through.

Optionally, in the device, the length of the baffle plate parallel to the moving direction of the pipette tips in the box body 1 is smaller than that of the baffle plate perpendicular to the moving direction of the pipette tips, so that the moving time of the pipette tips in the vertical state between the gaps 2 is reduced, the number of the through holes 6 in each row is increased, and the box forming speed is increased.

Fig. 3 is an enlarged schematic structural view of the pick 9. As shown in fig. 3, the pick 9 is T-shaped and is composed of a handle 5 and a thin plate 4 which is perpendicular to the handle 5 and has a length equal to the width of the box body 1. The paddle 9 can be used to guide the pipette tips in the upright position to move along the gap 2 of the partition strip 3 into the passage hole 6, so that the pipette tips are inserted from the passage hole 6 into the tip holes 8.

It should be understood that the handle 5 may have any length, and the present invention is not limited thereto.

The sheet 4 is of a length equal to that of the cassette 1 so that the lance tip in an upright position in each gap 2 can be guided to move through the bore 6. It should be understood that the width of the sheet 4 may be any, and the invention is not limited thereto.

It should be understood that the shifting piece 9 can be manually placed inside the box body 1 by an operator to guide the vertical lance tip, and can also be in sliding connection with a side baffle of the box body 1, and the operator can slide along the side baffle in the box body 1 to guide the lance tip to move. Of course, the paddle 9 may also guide the movement of the lance tip in other ways, and the invention is not limited thereto.

Preferably, the pipette tip boxing device can be made of polyethylene materials resistant to high-temperature sterilization, so that the device can be cleaned and sterilized by the materials without damage, and the recycling of the device is ensured.

The process of performing box forming operation by using the box forming device of the pipette tip provided by the invention can be divided into the following steps:

the method comprises the following steps: aligning at least one through hole 6 with one row of gun head holes 8 of a pipette gun box 7;

step two: pouring a plurality of pipette heads of the pipette into the fence plate;

step three: slightly shaking the box body 1 to enable the tips of the liquid-transfering guns to be clamped between the gaps 2 in an upright state;

step four: a row of pipette tips in an upright state is guided to move along the gap 2 to the passing hole 6 by using a plectrum 9 so that the pipette tips are inserted into the tip holes 8 from the passing hole 6;

step five: and repeating the first step to the fourth step to finish the box forming process of the plurality of pipette tips of the pipette.

In order to be able to pack the tips more efficiently, the cartridge 1 of the device can be fitted with the pipette cartridge 7 in different ways. For example, the cartridge 1 can be slid over the pipette magazine 7 so that at least one passage hole 6 is aligned in a row with one of the rows of gun head holes 8; the case 1 may also be manually placed over the pipette magazine 7 so that the holes 6 are aligned in rows with the one row of tip holes 8, the invention not being limited thereto.

Therefore, according to the pipette head boxing device provided by the embodiment of the invention, quick boxing of the pipette head can be realized, the working efficiency is improved, meanwhile, the device is simple in structure, low in cost and easy to clean, the number of times of contact between the pipette head and parts and personnel is reduced in the sequencing process, the pollution risk is greatly reduced, and the experimental accuracy is improved.

It should be noted that the foregoing examples have been provided merely for the purpose of explanation and are in no way to be construed as limiting of the present invention. While the present invention has been described in terms of exemplary embodiments, it is understood that the words which have been used herein are words of description and illustration, rather than words of limitation. Changes may be made, within the purview of the appended claims, as presently stated and as amended, without departing from the scope and spirit of the present invention in its aspects. Although the invention has been described herein with reference to particular means, materials and embodiments, the invention is not intended to be limited to the particulars disclosed herein; rather, the invention extends to all functionally equivalent structures, methods and uses, such as are within the scope of the appended claims.

Claims

1. A pipetting gun tip cartoning device for inserting pipetting gun tips into a tip hole (8) of a pipetting gun cartridge (7), comprising:

a box body (1) which is arranged above the pipette box (7) and is used for containing the pipette heads to be boxed, wherein a fence plate and at least one through hole (6) which can enable the pipette head to pass through are arranged in the box body (1), the barrier plate is composed of at least one strip-shaped partition strip (3), any two adjacent partition strips (3) are arranged in parallel, so that the pipette heads can be clamped between the gaps (2) of the two adjacent partition strips (3) in an upright state, the distance between the fence plate and the pipette box (7) is more than or equal to the length of the pipette head, the through holes (6) are integrally arranged at the end parts of two adjacent partition strips (3), and the number of said passage holes (6) and the number of said gaps (2) are equal, the width of the passage hole (6) is greater than the width of the gap (2);

the poking sheet (9) consists of a handle (5) and a thin plate (4) which is perpendicular to the handle (5) and has the length equal to the width of the box body (1), and is used for guiding the upright liquid-transfering gun head to move to the through hole (6) along the gap (2) of the isolating strip (3);

and the pipette gun box (7) is arranged below the box body (1), and a gun head hole (8) is used for receiving the pipette gun head passing through the passing hole (6).

2. The device according to claim 1, characterized in that the partition strips (3) of any two adjacent partitions are arranged in parallel with equal distance therebetween.

3. The device according to claim 1, characterized in that the cartridge (1) further comprises: a bottom plate having a length less than or equal to the length of the partition bar (3) and not covering the passage hole (6).

4. The device according to claim 1, characterized in that the box body (1) is provided with baffles on the side, and the length of the baffles in the box body (1) parallel to the moving direction of the pipette tips is smaller than the length of the baffles perpendicular to the moving direction of the pipette tips.

5. Device according to claim 1, characterized in that the passage opening (6) is semicircular with a diameter larger than the largest diameter of the pipette tip.

6. Device according to claim 1, characterized in that the passage hole (6) is oblong, the width of which is greater than the maximum diameter of the pipette tip.

7. The device according to any one of claims 1 to 6, wherein the device is made of a polyethylene material resistant to high temperature sterilization.

8. A method of boxing using the pipetting gun tip boxing apparatus of any one of claims 1 to 7, comprising the steps of:

the method comprises the following steps: aligning at least one of said through holes (6) with one of the rows of gun head holes (8) of the pipette gun magazine (7);

step two: pouring a plurality of pipette heads of the liquid-transfering gun onto the fence plate;

step three: slightly shaking the box body (1) to enable the plurality of pipette tips to be clamped between the gaps (2) in an upright state;

step four: using the plectrum (9) to guide a row of the pipette tips in an upright state to move along the gap (2) to the passing hole (6) so that the pipette tips are inserted into the tip holes (8) from the passing hole (6);

step five: and repeating the first step to the fourth step to finish the box forming process of the plurality of pipette tips.

9. The method according to claim 8, wherein said aligning at least one of said through holes (6) with one of the rows of pipette head holes (8) of said pipette gun magazine (7) comprises:

-aligning at least one of said through holes (6) with said one of the rows of gun head holes (8) of said pipetting gun magazine (7) by sliding said magazine (1).