CN108393104A - Syringe pump for micro-fluidic chip - Google Patents
Syringe pump for micro-fluidic chip Download PDFInfo
- Publication number
- CN108393104A CN108393104A CN201810316346.0A CN201810316346A CN108393104A CN 108393104 A CN108393104 A CN 108393104A CN 201810316346 A CN201810316346 A CN 201810316346A CN 108393104 A CN108393104 A CN 108393104A
- Authority
- CN
- China
- Prior art keywords
- micro
- fluidic chip
- syringe pump
- motor
- lead screw
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/50273—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the means or forces applied to move the fluids
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/04—Moving fluids with specific forces or mechanical means
- B01L2400/0475—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
- B01L2400/0481—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure squeezing of channels or chambers
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- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Dispersion Chemistry (AREA)
- Analytical Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Hematology (AREA)
- Clinical Laboratory Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
Abstract
This application discloses a kind of syringe pumps for micro-fluidic chip, including shell, the housing tip is recessed to be formed with a fitting groove, motor cabinet, sliding block, cylinder base and lead screw motor are provided in the fitting groove, the lead screw motor includes motor and lead screw, the nut coordinated with lead screw is fixed on the sliding block, sliding block is displaced under the action of lead screw between motor cabinet and cylinder base.The present invention drives syringe work by lead screw motor, can improve injection precision.
Description
Technical field
This application involves microfluidic arts, more particularly to a kind of syringe pump for micro-fluidic chip.
Background technology
Micro-fluidic chip (microfluidicchip) because its can integrate etc. with low consumption, quick, a variety of analytic functions it is excellent
The Important Platform put and studied as the fields such as biology, chemistry microanalysis in recent years.Since microfluidic chip analysis is at one
On several square centimeter chips, the micron order of network characterization separation analysis channel in, by nanoliter even picoliters grade samples sizes
Quick manipulation, and realize the one of the operations such as the sample preparation involved by biochemical test, sample introduction, mixing, reaction, separation, detection
Kind invention analytical technology.
The driving of fluid, is generally realized by syringe pump in micro-fluidic chip raceway groove, and syringe pump in the prior art exists
Control accuracy is poor, part is more, complicated, built-up time length problem.
Invention content
The purpose of the present invention is to provide a kind of syringe pump for micro-fluidic chip, with overcome it is in the prior art not
Foot.
To achieve the above object, the present invention provides the following technical solutions：
The embodiment of the present application discloses a kind of syringe pump for micro-fluidic chip, including shell, the recessed shape of the housing tip
Cheng Youyi fitting grooves, motor cabinet, sliding block, cylinder base and lead screw motor are provided in the fitting groove, and the lead screw motor includes electricity
Machine and lead screw are fixed with the nut coordinated with lead screw on the sliding block, and sliding block is displaced into motor cabinet and cylinder under the action of lead screw
Between seat.
Preferably, in the above-mentioned syringe pump for micro-fluidic chip, the motor cabinet is integrally formed, including horizontal
Top plate and side plate with top plate l-shaped, surround a motor installation cavity, the motor is set to institute between motor cabinet and shell
It states in motor installation cavity.
Preferably, in the above-mentioned syringe pump for micro-fluidic chip, the edge supports of the top plate are in the top of shell
End margin.
It preferably, can by screw between the top plate and shell in the above-mentioned syringe pump for micro-fluidic chip
Dismantling connection.
Preferably, in the above-mentioned syringe pump for micro-fluidic chip, be connected between the motor cabinet and cylinder base to
A few optical axis, optical axis is horizontally disposed, and slide block set is set on optical axis and can be moved along optical axis.
Preferably, it in the above-mentioned syringe pump for micro-fluidic chip, is formed on the sliding block to syringe pull rod
The first card slot that cap is limited.
Preferably, in the above-mentioned syringe pump for micro-fluidic chip, the cylinder base is integrally formed, including horizontal top
Seat and the support plate with footstock l-shaped, the upper surface of footstock is recessed to be formed with the V-shaped groove supported for injector syringe.
Preferably, it in the above-mentioned syringe pump for micro-fluidic chip, is formed with to injector syringe on the footstock
The second card slot that cap is limited.
Preferably, in the above-mentioned syringe pump for micro-fluidic chip, the edge supports of the footstock are in the top of shell
End margin.
It preferably, can by screw between the cylinder base and shell in the above-mentioned syringe pump for micro-fluidic chip
Dismantling connection.
Compared with the prior art, the advantages of the present invention are as follows：The present invention drives syringe work by lead screw motor, can be with
Improve injection precision.
Description of the drawings
In order to illustrate the technical solutions in the embodiments of the present application or in the prior art more clearly, to embodiment or will show below
There is attached drawing needed in technology description to be briefly described, it should be apparent that, the accompanying drawings in the following description is only this
Some embodiments described in application, for those of ordinary skill in the art, without creative efforts,
Other drawings may also be obtained based on these drawings.
Fig. 1 show the dimensional structure diagram of syringe pump in the specific embodiment of the invention；
Fig. 2 show the perspective exploded view of syringe pump in the specific embodiment of the invention；
Fig. 3 show the schematic cross-section of sliding block in the specific embodiment of the invention；
Fig. 4 show the schematic cross-section of cylinder base in the specific embodiment of the invention.
Specific implementation mode
Technical scheme of the present invention is clearly and completely described below in conjunction with attached drawing, it is clear that described implementation
Example is a part of the embodiment of the present invention, instead of all the embodiments.Based on the embodiments of the present invention, ordinary skill
The every other embodiment that personnel are obtained without making creative work, shall fall within the protection scope of the present invention.
In the description of the present invention, it should be noted that term "center", "upper", "lower", "left", "right", "vertical",
The orientation or positional relationship of the instructions such as "horizontal", "inner", "outside" be based on the orientation or positional relationship shown in the drawings, merely to
Convenient for the description present invention and simplify description, do not indicate or imply the indicated device or element must have a particular orientation,
With specific azimuth configuration and operation, therefore it is not considered as limiting the invention.In addition, term " first ", " second ",
" third " is used for description purposes only, and is not understood to indicate or imply relative importance.
In the description of the present invention, it should be noted that unless otherwise clearly defined and limited, term " installation ", " phase
Even ", " connection " shall be understood in a broad sense, for example, it may be being fixedly connected, may be a detachable connection, or be integrally connected；It can
Can also be electrical connection to be mechanical connection；It can be directly connected, can also indirectly connected through an intermediary, Ke Yishi
Connection inside two elements.For the ordinary skill in the art, above-mentioned term can be understood at this with concrete condition
Concrete meaning in invention.
In conjunction with shown in Fig. 1 and Fig. 2, the present embodiment provides a kind of syringe pumps for micro-fluidic chip, including shell 10, electricity
Engine base 20, sliding block 30 and cylinder base 40.
The top surface of shell 10 is recessed to be formed with a fitting groove 101, and motor cabinet 20, sliding block 30 and cylinder base 40 are set to fitting groove
In 101.
Motor cabinet 20 is integrally formed, including horizontal top plate 201 and the side plate 202 with 201 l-shaped of top plate, motor cabinet
A motor installation cavity is surrounded between 20 and shell 10.
In the technical solution, top plate 201 plays the role of covering protection, and the motor installation cavity surrounded plays guarantor to motor
Protect the effect of isolation.The through-hole 2021 and motor pilot hole 2022 that screw mandrel is worn are offered on side plate 202, in assembling,
First lead screw motor can be installed by screw and motor cabinet 20, then again by lead screw motor and motor cabinet integral installation in shell
On, operating aspect is simple in structure.
Lead screw motor (not shown) is provided in motor installation cavity, lead screw motor includes motor and lead screw, is consolidated on sliding block 30
Surely there is the nut coordinated with lead screw.
The power supply string holes 102 being connected to motor installation cavity are offered on shell 10, power cord can pass through power supply string holes 102
It is connect with motor.
In one embodiment, power supply string holes are opened on the side wall of shell, will be readily apparent, and power supply string holes can also be opened
Set on the bottom surface of shell.
Further, the width of top plate 201 is more than the width of fitting groove 101, therefore, after motor cabinet 20 is installed, top plate
201 edge supports are in the tip edge of shell 10.
It is detachably connected by screw between motor cabinet 20 and shell 10.
In one embodiment, the side wall of shell 10 runs through up and down mounting hole 103, the bottom surface of the top plate 201 of motor cabinet 20
It is equipped with screw hole.
In the technical solution, screw is installed from the bottom surface of shell, certain waterproof action can be played to screw, together
When, it does not affect the appearance.
In one embodiment, the end rotational support of lead screw is on cylinder base 40.By multi-point support to keep lead screw to be in
Horizontal position, to ensure its precision and service life.
Sliding block 30 can be displaced under the action of lead screw between motor cabinet 20 and cylinder base 40.It is formed on sliding block 30 pair
The first card slot 301 that syringe rod cap is limited.
In order to ensure stability of the sliding block 30 in moving process, at least one is also associated between motor cabinet 20 and cylinder base 40
Optical axis 50, optical axis 50 is horizontally disposed, and sliding block 30 is sheathed on optical axis 50 and can be moved along optical axis 50.
In one embodiment, optical axis 50 is provided with arranged side by side three, and three optical axises 50 are arranged in isosceles triangle.
In the technical solution, pass through three non-coplanar optical axises, it is ensured that the stability in 30 moving process of sliding block, it is sliding
Block 30 is not susceptible to shake.
In the technical solution, optical axis constitutes the track of guide slides movement, while also having the work limited to sliding block
With.
In one embodiment, it is detachably connected between nut and sliding block 30.
In the technical solution, nut is split settings with sliding block, and one side low manufacture cost on the other hand can be according to need
It is worn after replacing nut, such as nut long-time use.
Cylinder base 40 is integrally formed, including horizontal footstock 401 and the support plate 402 with 401 l-shaped of footstock.
The upper surface of footstock 401 is recessed to be formed with the V-shaped groove 403 supported for syringe.
In the technical solution, V-shaped groove 403 extends along the direction of travel of sliding block, and two bottom surfaces of V-shaped groove are respectively to syringe
Symmetrical both sides form support, are linear contact between V-shaped groove and syringe.
The second card slot 404 limited to injector syringe cap is also formed on footstock 401.
In one embodiment, the width of footstock 401 is more than the width of fitting groove 101, therefore, after cylinder base 40 is installed, footstock
401 edge supports are in the tip edge of shell 10.
It is detachably connected by screw between cylinder base 40 and shell 10.
In one embodiment, the side wall of shell 10 runs through up and down has mounting hole 104, the bottom surface of the footstock 401 of cylinder base 40 to match
Conjunction is provided with screw hole.
In the technical solution, screw installs cylinder base from the bottom surface of shell, and certain waterproof can be played to screw
Effect, meanwhile, it does not affect the appearance.
Support plate 402 is oppositely arranged with side plate 202, and the end rotational support of lead screw is in support plate 402, and the two of optical axis 50
End is individually fixed in support plate 402 and side plate 202.
In conjunction with shown in Fig. 3, the pressing plate 405 close to or away from V-shaped groove 403, pressing plate 405 and top are additionally provided on footstock 401
The first screw rod 406 is provided between seat 401, the first screw rod 406 is rotated to drive pressing plate 405 close to or away from V-shaped groove 403.
Further, pressing plate 405 is sheathed on the first screw rod 406, and screw hole 407, the first screw rod are provided on footstock 401
Screw-thread fit between 406 and footstock 401.
In the technical solution, the second card slot 404 coordinates with syringe cap to limit the movement of syringe axial direction, and V-shaped groove acts on
Syringe both sides are adapted to the syringe of different-diameter to realize the movement to syringe transverse direction；Pressing plate function is in the top of syringe
Face is to realize the limit to syringe vertical direction.
In conjunction with shown in Fig. 4, the first card slot 301 includes the baffle 3011 being oppositely arranged and driving plate 3012, driving plate 3012
It is connect with actuator 3013, actuator 3013 acts on driving plate 3012 and can drive it in a first direction close to or away from gear
Plate 3011, first direction are the moving direction of sliding block.
In the technical solution, the rod cap of syringe limits between baffle 3011 and driving plate 3012, passes through driving plate
Rod cap can be extruded in the first card slot by 3012 movement, realize being relatively fixed between rod cap and sliding block.
Further, the top of baffle 3011 is recessed downwards is formed with V-shaped groove 3014.
In the technical solution, V-shaped groove 3014 is supported to the pull rod to syringe, while realizing the transverse direction to pull rod
Limit.
Further, further include a fixed plate 3015, fixed plate 3015 is oppositely arranged with driving plate 3012, fixed plate 3015
It is detachably fixed between sliding block, driving plate 3012 is set between fixed plate 3015 and baffle 3011, and actuator 3013 is one
Screw rod, screw-thread fit between the screw rod and fixed plate 3015, the end effect of screw rod is in driving plate.
In the technical solution, by rotating screw rod, to drive driving plate close to or away from baffle 3011.
In one embodiment, fixed plate 3015 passes through fixed between screw and sliding block.
Further, the side of sliding block 30 is also formed with the stage portion 302 limited to 3015 side of fixed plate.Step
Portion is formed in the surrounding of the first card slot.
The operation principle of the present embodiment syringe pump is：Motor is rotated to drive lead screw to rotate, lead screw and nut coordinate with
Band movable slider is moved along optical axis, opposite between the syringe and cylinder base of syringe since pull rod and the sliding block of syringe are relatively fixed
It is fixed, so accurate action of injection may be implemented by the movement of sliding block.
Finally it should be noted that：The above embodiments are only used to illustrate the technical solution of the present invention., rather than its limitations；To the greatest extent
Present invention has been described in detail with reference to the aforementioned embodiments for pipe, it will be understood by those of ordinary skill in the art that：Its according to
So can with technical scheme described in the above embodiments is modified, either to which part or all technical features into
Row equivalent replacement；And these modifications or replacements, various embodiments of the present invention technology that it does not separate the essence of the corresponding technical solution
The range of scheme.
Claims (10)
1. a kind of syringe pump for micro-fluidic chip, which is characterized in that including shell, the housing tip is recessed to be formed with a dress
Slot allocation, is provided with motor cabinet, sliding block, cylinder base and lead screw motor in the fitting groove, and the lead screw motor includes motor and lead screw,
The nut coordinated with lead screw is fixed on the sliding block, sliding block is displaced under the action of lead screw between motor cabinet and cylinder base.
2. the syringe pump according to claim 1 for micro-fluidic chip, which is characterized in that motor cabinet one at
Type, including horizontal top plate and the side plate with top plate l-shaped, surround a motor installation cavity between motor cabinet and shell, described
Motor is set in the motor installation cavity.
3. the syringe pump according to claim 2 for micro-fluidic chip, which is characterized in that the edge supports of the top plate
In the tip edge of shell.
4. the syringe pump according to claim 3 for micro-fluidic chip, which is characterized in that between the top plate and shell
It is detachably connected by screw.
5. the syringe pump according to claim 1 for micro-fluidic chip, which is characterized in that the motor cabinet and cylinder base it
Between be connected with an at least optical axis, optical axis is horizontally disposed, and slide block set is set on optical axis and can be moved along optical axis.
6. the syringe pump according to claim 1 for micro-fluidic chip, which is characterized in that be formed on the sliding block pair
The first card slot that syringe rod cap is limited.
7. the syringe pump according to claim 1 for micro-fluidic chip, which is characterized in that the cylinder base is integrally formed,
Support plate including horizontal footstock and with footstock l-shaped, recessed be formed in the upper surface of footstock support for injector syringe
V-shaped groove.
8. the syringe pump according to claim 7 for micro-fluidic chip, which is characterized in that be formed on the footstock pair
The second card slot that injector syringe cap is limited.
9. the syringe pump according to claim 7 for micro-fluidic chip, which is characterized in that the edge supports of the footstock
In the tip edge of shell.
10. the syringe pump according to claim 7 for micro-fluidic chip, which is characterized in that the cylinder base and shell it
Between be detachably connected by screw.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810316346.0A CN108393104A (en) | 2018-04-10 | 2018-04-10 | Syringe pump for micro-fluidic chip |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810316346.0A CN108393104A (en) | 2018-04-10 | 2018-04-10 | Syringe pump for micro-fluidic chip |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN108393104A true CN108393104A (en) | 2018-08-14 |
Family
ID=63099904
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201810316346.0A Pending CN108393104A (en) | 2018-04-10 | 2018-04-10 | Syringe pump for micro-fluidic chip |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN108393104A (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20210205806A1 (en) * | 2018-09-29 | 2021-07-08 | Dgi Tech (Qing Dao) Co., Limited | Microfluidic chip system and method for preparing droplets |
| US20230146582A1 (en) * | 2021-11-05 | 2023-05-11 | Toyota Motor Engineering & Manufacturing North America, Inc. | Systems and methods for measuring low speed fluid flow |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103511216A (en) * | 2013-09-25 | 2014-01-15 | 中国科学技术大学 | Injection pump, injection system and injection method |
| CN203634585U (en) * | 2013-12-24 | 2014-06-11 | 中国科学技术大学 | Injector handle tail end assembling mechanism in injection pump |
| CN205528836U (en) * | 2016-04-13 | 2016-08-31 | 天津卫凯生物工程有限公司 | A culture solution feeding device for cell perfusion culture |
| CN208213207U (en) * | 2018-04-10 | 2018-12-11 | 苏州讯飞科学仪器有限公司 | Syringe pump for micro-fluidic chip |
-
2018
- 2018-04-10 CN CN201810316346.0A patent/CN108393104A/en active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103511216A (en) * | 2013-09-25 | 2014-01-15 | 中国科学技术大学 | Injection pump, injection system and injection method |
| CN203634585U (en) * | 2013-12-24 | 2014-06-11 | 中国科学技术大学 | Injector handle tail end assembling mechanism in injection pump |
| CN205528836U (en) * | 2016-04-13 | 2016-08-31 | 天津卫凯生物工程有限公司 | A culture solution feeding device for cell perfusion culture |
| CN208213207U (en) * | 2018-04-10 | 2018-12-11 | 苏州讯飞科学仪器有限公司 | Syringe pump for micro-fluidic chip |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20210205806A1 (en) * | 2018-09-29 | 2021-07-08 | Dgi Tech (Qing Dao) Co., Limited | Microfluidic chip system and method for preparing droplets |
| US20230278034A1 (en) * | 2018-09-29 | 2023-09-07 | Dgi Tech (Qing Dao) Co., Limited | Method for preparing droplets using microfluidic chip system |
| US20230146582A1 (en) * | 2021-11-05 | 2023-05-11 | Toyota Motor Engineering & Manufacturing North America, Inc. | Systems and methods for measuring low speed fluid flow |
| US11885652B2 (en) * | 2021-11-05 | 2024-01-30 | Toyota Motor Engineering & Manufacturing North America, Inc. | Systems and methods for measuring low speed fluid flow |
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| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20180814 |
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| RJ01 | Rejection of invention patent application after publication |