CN108371732A - Myocardial protective liquid filling device - Google Patents

Myocardial protective liquid filling device Download PDF

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Publication number
CN108371732A
CN108371732A CN201810344006.9A CN201810344006A CN108371732A CN 108371732 A CN108371732 A CN 108371732A CN 201810344006 A CN201810344006 A CN 201810344006A CN 108371732 A CN108371732 A CN 108371732A
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CN
China
Prior art keywords
pipe
branch
pipeline
back segment
leading portion
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Granted
Application number
CN201810344006.9A
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Chinese (zh)
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CN108371732B (en
Inventor
戚晓敏
李欣
赵赟
胡克俭
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Zhongshan Hospital Fudan University
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Zhongshan Hospital Fudan University
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Priority to CN201810344006.9A priority Critical patent/CN108371732B/en
Publication of CN108371732A publication Critical patent/CN108371732A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3621Extra-corporeal blood circuits
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3621Extra-corporeal blood circuits
    • A61M1/3627Degassing devices; Buffer reservoirs; Drip chambers; Blood filters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3621Extra-corporeal blood circuits
    • A61M1/3653Interfaces between patient blood circulation and extra-corporal blood circuit
    • A61M1/3659Cannulae pertaining to extracorporeal circulation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3621Extra-corporeal blood circuits
    • A61M1/3664Extra-corporeal blood circuits for preparing cardioplegia solutions

Abstract

The invention discloses a kind of myocardial protective liquid filling devices comprising the first pipe for being transfused crystal myocardium protecting liquid is used for the second pipe of infused blood, and for realizing the bifurcated return circuit module that the two pipelines mutually switch, which includes:The both ends branch one with first pipe leading portion and first pipe back segment unicom respectively, the both ends branch two with second pipe leading portion and second pipe back segment unicom respectively, the both ends branch three with first pipe leading portion and second pipe back segment unicom respectively, the branch four with second pipe leading portion and first pipe back segment unicom, wherein branch three intersect with branch four respectively at both ends.The myocardial protective liquid filling device, which copes with, temporarily changes the elastic operation of pipeline, switching charge pump, adjustment pump head, quickly and accurately completes myocardial preservation perfusion.

Description

Myocardial protective liquid filling device
Technical field
The invention belongs to medical instruments fields, are related to a kind of openheart surgery auxiliary instrument, and in particular to a kind of cardiac muscle guarantor Protect perfusion device.
Background technology
Department of cardiac surgery routinely needs that myocardium protecting liquid is perfused to heart of patient during open heart operations so as to the heart Dirty to be operated period, heart is in electromechanical activity stationary state (" stoping jumping "), and after cardiac surgery procedure Allow cardiac flow restore and make heart restore bounce.The myocardium protecting liquid of Clinical practice is according to matrix liquid and ingredient at present Various combination can be divided into four kinds:Simple crystal myocardium protecting liquid, 4:(i.e. 4 parts of blood, the 1 part of crystal mixing of 1 myocardium protecting liquid containing blood Liquid), del Nido myocardium protecting liquids (i.e. 1 part of blood, 4 portions of crystal mixed liquors), high potassium oxygenated blood myocardium protecting liquid (“Microplegia”).In openheart surgery, by the way that myocardium protecting liquid is perfused, cardiac muscle can be protected to subtract during cardiac arrest The strike that light ischemic and subsequent refilling process are subjected to.Although only being faced with a kind of myocardium protecting liquid in an openheart surgery In bed practice, operator doctor offhand decision according to factors such as the personal feature of patient and the patient's condition sometimes before implementing to perform the operation Replace pre-prepd myocardium protecting liquid type.And different types of protection liquid needs the pipeline group combined pressure with different bores same In one perfusion blood pump or two blood pumps of different pump speeds combine to distinguish infused blood and crystalloid fluid, to ensure that use is pressed It is required that blood and crystal mixed proportion.Therefore when scene temporarily changes the former myocardium protecting liquid type selected, it is necessary to cut The pipeline of different bores is changed, or adjusts separately blood/crystal perfusion revolution speed to be converted.
On the other hand, it before aorta opening, when if necessary to antegrade perfusion homoiothermy, and/or needs through the suck-back that drives in the wrong direction When heart intracavity gas is discharged will pass through aortic root, routine operation is to close charge pump, and crystalloid fluid is taken out out of pump slot Pipeline and being pressed from both sides closes, and then readjusts that pump head is elastic, and such operating procedure is quite cumbersome, and blood is perfused in different brands The adjusting method of pump is also different, and the probability for maloperation occur is higher.If adjusting tension, the destruction of haemocyte is increased, The service life that can shorten pump head, does not have the effect of suck-back if adjusting pine yet.In addition, a whole set of myocardium protecting liquid intrusion pipe Road can lead to air inlet occur in case of maloperation, it is difficult to quickly be handled, cause patient's arterial system air inlet, lead to nerve A series of damages such as system injury, jeopardize operation and patient safety.Therefore in clinical extracorporal circulatory system work, pipe is temporarily changed It is the high-risk action of clinical mistake that road, switching, which are perfused blood pump, and/or adjust the elastic operation of pump head, often delays delay hand Art process even results in accident surgery generation, causes doctor-patient dispute, have serious consequences to patient and hospital.
For a long time, it faces to temporarily change pipeline, switching reperfusion mode, and/or adjusts the elastic operation of blood pump, even Skilled doctor and perfusionist with clinical experience for many years also inevitably malfunction when operating existing myocardial protective liquid filling device, Therefore how accurately promptly smoothly completing myocardial preservation perfusion and avoiding error is always the target that medical worker pursues.
Invention content
For the above problem for overcoming in existing myocardial protective liquid filling device, through to largely studying and testing repeatedly, We have invented a kind of new myocardial protective liquid filling devices.The specific technical solution of the present invention is as described below.
A kind of myocardial protective liquid filling device comprising:First pipe for being transfused crystal myocardium protecting liquid, the first pipe Road is divided into first pipe leading portion and first pipe back segment;For the second pipe of infused blood, second pipe is divided into second pipe Leading portion and second pipe back segment;With after occlusion pump first pipe back segment and second pipe back segment unicom, for realizing crystal Myocardium protecting liquid mixes with blood, is transfused the third pipeline of myocardium protecting liquid;For connecting second pipe leading portion and oxygenator 4th pipeline;For connecting second pipe leading portion and storing up the 5th pipeline of blood tank;One end and first pipe leading portion be connected the Six pipelines;The platform upper tube being connected with third pipeline;The bifurcated circuit mould mutually switched for realizing first pipe and second pipe Block;It is set to the bubble filter of the 6th pipeline other end;The crystal myocardium protecting liquid contact pin being connected with bubble filter;For Drive liquid flowing in first pipe and second pipe (such as driving first pipe infusion crystal myocardium protecting liquid and driving second Pipeline infused blood) occlusion pump;It is set in turn in cooling tube and bubble on third pipeline along myocardium protecting liquid infusion direction Catcher, wherein the bifurcated return circuit module is substantially in the figure of eight comprising:Both ends respectively with first pipe leading portion and first The branch one of pipeline back segment unicom, the branch two with second pipe leading portion and second pipe back segment unicom, both ends are divided respectively at both ends Not with the branch three of first pipe leading portion and second pipe back segment unicom, both ends respectively with after second pipe leading portion and first pipe The branch four of Duan Liantong, wherein branch three intersect with branch four but are not connected to;The internal diameter of first pipe back segment is after second pipe The half of the internal diameter of section, i.e. the inner hole section product of first pipe back segment are four points of the inner hole section product of second pipe back segment One of.
In a preferred embodiment, above-mentioned 6th pipeline can with bifurcated be two, and respectively with a bubble mistake Filter unicom, each bubble filter are connected with a crystal myocardium protecting liquid contact pin.Such structure makes crystal cardiac muscle protect Shield stoste contact pin becomes double needle by single needle, improves 1:4 myocardium protecting liquids containing blood (i.e. 1 part of blood myocardium protecting liquid) are simple brilliant First pipe (crystal access) generates gas because of high flow capacity hydraulic shock in bubble filter when body myocardial preservation perfusion Crystalloid fluid mistake is being replaced when steeping and so that bubble is entered the situation of first pipe since flow velocity is very fast, while avoiding single infusion Bubble is led to the problem of in journey.
Preferably, it is provided with female Luer on the 4th pipeline, to be connected with oxygenator.(such as due to certain oxygenators Medos, Dideco, Maquet etc.) female Luer is come with, therefore the female Luer to match is arranged on the 4th pipeline can Easily to realize connection.
In one embodiment, third pipeline is connected with platform upper tube by female Luer or two-way joint.
In order to avoid doctor is in operation fast resolution first pipe and second pipe, it is preferable that first pipe and branch one Color it is different from the color of second pipe and branch two;Or a kind of labeling of color is fixed on first pipe and branch one On, and the labeling of another color is fixed on second pipe and branch two, to which two lines road be distinguished.
For the ease of the connection of each pipeline to each other, can be attached using three-way connection between three pipelines.Three Logical size and the diameter dimension of each pipeline match.Such as first pipe back segment, second pipe back segment and third pipeline are logical A three-way connection is crossed to be connected.For example, when first pipe internal diameter is 1/8 inch, second pipe and third internal diameter of the pipeline are all At 1/4 inch, which can be the threeway of 1/4 × 1/4 × 1/8 (inch).
Similarly, second pipe leading portion, the 4th pipeline and the 5th pipeline are connected by a three-way connection.For example, working as When these three internal diameter of the pipeline are all 1/4 inch, which can be the threeway of 1/4 × 1/4 × 1/4 (inch).First pipe Road leading portion, branch one and branch three are connected by a three-way connection;First pipe back segment, branch one and branch four pass through one A three-way connection is connected;Second pipe leading portion, branch two and branch four are connected by a three-way connection;After second pipe Section, branch two are connected with branch three by a three-way connection.
In one embodiment, first pipe leading portion, second pipe leading portion, third pipeline, the 4th pipeline, the 5th pipe Tubing clamp (can also be replaced with gripping pliers) is respectively equipped on road, branch one, branch two, branch three and branch four, to control Liquid flowing in each pipeline.
In a preferred embodiment, bubble trap is provided with after cooling tube on third pipeline.
Preferably, above-mentioned first pipe internal diameter is the 1/2 of second pipe internal diameter, such as 1/ that first pipe internal diameter is routine 8 inches, second pipe internal diameter is 1/4 inch of routine.
The myocardial protective liquid filling device of the present invention can quickly and accurately complete following 5 kinds of perfusions switching modes:1. Blood (oxygenated blood) is perfused;2. blood:Crystal 4:1 perfusion;3. blood:Crystal 1:4 perfusions;4. simple crystal perfusion;5. reverse suck-back Blood.When significantly reducing in openheart surgery because temporarily changing myocardium protecting liquid type, each pouring liquid of adjustment and changing bottle/bag Due to pulling out faulty operation incidence caused by needle and contact pin are acted hurriedly in a messy situation, operating time can be effectively shortened, avoid malpractice, And be conducive to the rehabilitation of patient.
Description of the drawings
Fig. 1 is the structural schematic diagram of a myocardial protective liquid filling device embodiment according to the present invention;
Fig. 2 is the schematic diagram of the monocrystal perfusion mode of myocardial protective liquid filling device shown in Fig. 1;
Fig. 3 is the schematic diagram of blood (oxygenated blood) reperfusion mode of myocardial protective liquid filling device shown in Fig. 1;
Fig. 4 is the schematic diagram of the del Nido myocardium protecting liquid reperfusion modes of myocardial protective liquid filling device shown in Fig. 1;
Fig. 5 is 4 of myocardial protective liquid filling device shown in Fig. 1:The schematic diagram of 1 reperfusion mode of myocardium protecting liquid containing blood;
Fig. 6 is the schematic diagram of the reverse suck-back blood mode of myocardial protective liquid filling device shown in Fig. 1.
Reference sign:1, first pipe;11, first pipe leading portion;12, first pipe back segment;2, second pipe; 21, second pipe leading portion;22, second pipe back segment;3, third pipeline;4, the 4th pipeline;5, the 5th pipeline;6, the 6th pipeline; 7, platform upper tube;8, bifurcated return circuit module;81, branch one;82, branch two;83, branch three;84, branch four;9, myocardium protecting liquid Device for casting;91, bubble filter;92, contact pin;93, occlusion pump;94, cooling tube;95, bubble trap;96, female Luer; 97, three-way connection;98, tubing clamp;99, blood tank is stored up.
Specific implementation mode
Below in conjunction with attached drawing, technical scheme of the present invention is described.Obviously, described embodiment is only this Shen Please a part of embodiment, rather than whole embodiment;And structure shown in attached drawing is only schematical, not Represent material object.It should be noted that based on these embodiments in the present invention, those of ordinary skill in the art are obtained all Other embodiment shall fall in the protection scope of this application.
For the sake of description simplicity, " myocardium protecting liquid " is referred to as to " protection liquid " sometimes herein, they indicate identical Meaning, may be used interchangeably.
Herein, term " simple crystal myocardium protecting liquid ", " pure crystalloid fluid ", " crystal protection liquid ", " pure crystal " and " crystalloid fluid " indicates identical meaning, may be used interchangeably.Similarly, " oxygenated blood ", " blood ", " pure blood " or " blood " indicates Identical meaning, may be used interchangeably.
Herein, term " 4:1 myocardium protecting liquid containing blood ", " 4 parts of blood myocardium protecting liquids " and " 4 parts of blood " indicate identical Meaning may be used interchangeably.Similarly, term " del Nido myocardium protecting liquids ", " 1:4 myocardium protecting liquids containing blood " and " 4 parts of crystalline substances Body (liquid) " indicates identical meaning, may be used interchangeably.
Herein, term " pipeline ", " pipeline " and " (leading) manages " indicate identical meaning, may be used interchangeably.
Herein, term " occlusion pump ", " charge pump ", " blood pump ", " pump head " and " pump " indicates identical meaning, can be with It is used interchangeably.
Herein, term " preceding (end) " indicates the direction upstream being transfused towards patient on operating table along myocardium protecting liquid Position relationship, but be not meant to must be directed towards a certain fixed-direction in actual installation practice, just to show all parts Between position relationship or connection relation.Similarly, term " rear ", " upper (side) ", "lower" etc. do not constitute absolute space and close System limits, only a kind of concept of relative position.This, which is those skilled in the art, to understand.
Myocardial protective liquid filling device 9
Referring to Fig. 1, myocardial protective liquid filling device 9 of the invention includes mainly:For being transfused crystal myocardium protecting liquid First pipe 1, first pipe 1 are divided for first pipe leading portion 11 and first pipe back segment 12;Second pipe for infused blood 2, second pipe 2 divides for second pipe leading portion 21 and second pipe back segment 22;First pipe back segment 12 after occlusion pump 93 With the third pipeline 3 of 22 unicom of second pipe back segment, third pipeline 3 mixes with blood for realizing crystal myocardium protecting liquid, is defeated Note myocardium protecting liquid;The 4th pipeline 4 for connecting second pipe leading portion 21 and oxygenator (not shown);For connecting the second pipe 5th pipeline 5 of road leading portion 21 and storage blood tank;The 6th pipeline 6 that one end is connected with first pipe leading portion 11;With third pipeline 3 Connected platform upper tube 7;It is set to the bubble filter 91 of 6 other end of the 6th pipeline;The crystal heart being connected with bubble filter 91 Flesh protects liquid contact pin 92;For driving in first pipe 1 and second pipe 2 liquid flowing, (for example driving first pipe 1 is transfused Crystal myocardium protecting liquid and driving second pipe 2 infused blood) occlusion pump 93;It is set gradually along myocardium protecting liquid infusion direction In cooling tube 94 and bubble trap 95 on third pipeline 3.
In order to which the perfusion for making myocardial protective liquid filling device 9 have a variety of myocardium protecting liquids switches, it is necessary to it is brilliant to integrate infusion The pipeline of body myocardium protecting liquid and infused blood.First pipe 1 and second pipe 2 can be made to carry out for this purpose, the present invention has devised The oblique circuits network mutually switched, i.e. bifurcated return circuit module 8.The bifurcated loop network is by first pipe 1 and second pipe 2 All it is divided into front and back two sections, i.e. the front and rear sides of bifurcated return circuit module 8 are all connected with first pipe 1 and second pipe 2 respectively.
Referring to Fig. 2, the bifurcated return circuit module 8 in myocardial protective liquid filling device 9 is substantially in the figure of eight comprising:Both ends Respectively with the branch 1 of 12 unicom of first pipe leading portion 11 and first pipe back segment, between a-b;Both ends are respectively with second The branch 2 82 of 22 unicom of pipeline leading portion 21 and second pipe back segment, between c-d;Both ends respectively with first pipe leading portion 11 With the branch 3 83 of 22 unicom of second pipe back segment, between a-d;Both ends respectively with second pipe leading portion 21 and first pipe The branch 4 84 of 12 unicom of back segment, between c-b, wherein branch 3 83 intersects with branch 4 84 but is not connected to.
Due to being provided with bifurcated return circuit module 8, two bores fluid path, that is, first pipe 1 and second pipe 2 it Between increase 4 three Y connections 97, form that two-way is parallel, two-way intersects, i.e., branch 1 and branch 2 82 be parallel, branch three 83 intersect with branch 4 84,
So as to by the folder 98 or with gripping pliers (not shown) clamp different intersection dypass 81-84 of blocking of blinding off a line, Pure crystal can be perfused, 4:1 myocardium protecting liquid containing blood, 1:The 4 Nido myocardium protecting liquids of del containing blood, the simple blood and reverse of filling Directly switch between suck-back.As long as example, folder close cross section (branch 3 83 and branch 4 84) can be into promoting circulation of blood:Crystal 4:1 Perfusion;Folder closes parallel section (branch 1 and branch 2 82) can be into promoting circulation of blood:Crystal 1:4;Folder closes crystal tubing proximal end (first Pipeline leading portion 11) it is exactly simple filling blood;Folder closes bloody path proximal end (second pipe leading portion 21) and can be carried out simple irrigation crystal body;It does not press from both sides Stopped pipe road can then carry out reverse suck-back, and five kinds of states can arbitrarily switch.Such interim handover operation in scene does not have to certain For root pipeline from 93 inner taking-up of pump head, without readjusting, pump head 93 is elastic, easy to use, not error-prone.
In the present invention, " first pipe 1 " is known as " crystal woven hose 1 " sometimes, to make its effect definitely.
Second pipe 2 is used for blood circulation.For the sake of for convenience of description, oxygenated blood herein may be simply referred to as " blood ", " pure Blood " or " blood ".
In order to realize blood in the case where first pipe 1 and second pipe 2 share occlusion pump 93:Crystal 4:1 perfusion Mode and blood:Crystal 1:The switching of 4 reperfusion modes, the internal diameter of first pipe back segment 12 are the two of the internal diameter of second pipe back segment 22 / mono-, i.e. the inner hole section product of first pipe back segment 12 is a quarter of the inner hole section product of second pipe back segment 22, from And so that the fluid flow of first pipe back segment 12 is a quarter of the fluid flow of second pipe back segment 22.
Preferably, first pipe leading portion 11 is identical with the internal diameter of first pipe back segment 12;And 21 He of second pipe leading portion The internal diameter of second pipe back segment 22 is identical.For example, the internal diameter of first pipe 1 is 1/8 inch of routine, the internal diameter of second pipe 2 It is conventional 1/4 inch.
Above-mentioned cooling tube 94 is a kind of myocardial preservation liquid heat exchanger 94, external temperature changing water bank or can be put into ice bucket, be used for Myocardium protecting liquid cools down, to be suitable for being perfused.
The rotation direction of occlusion pump 93 can switch, when rotating forward, for driving first pipe 1 and second to manage Liquid is flowed towards platform upper tube 7 in road 2, and driving first pipe 1 is transfused crystal myocardium protecting liquid and driving second pipe 2 is transfused blood Liquid provides myocardium protecting liquid for patient.When turned reversely, by retrograde suck-back, gas in the chambers of the heart is discharged by aortic root Body, at this time air containing fluid (blood) flowed from platform upper tube 7 to 3 direction of third pipeline.
Bubble trap 95 is for ensureing perfusion safety and monitoring myocardium protecting liquid injection pressure so that myocardium protecting liquid Device for casting 9 is safe to use, and bubble can be made to stay in the container.It can continue to fill generating bubble due to operation error Note, ensure that the safety of operation as far as possible.
In a preferred embodiment, as shown in Figure 1, the 6th pipeline 6 can with bifurcated be two, and respectively with one 91 unicom of bubble filter, each bubble filter 91 are connected with a crystal myocardium protecting liquid contact pin 92.Such structure So that crystal myocardium protecting liquid contact pin 92 is become double needle by single needle, is inserted into respectively in two bottle/bag crystalloid fluids, improves 1:4 contain blood First pipe 1 easy tos produce the situation of bubble because of high flow capacity when myocardium protecting liquid (i.e. 1 part of blood myocardium protecting liquid) is perfused, simultaneously When avoiding single infusion bubble is led to the problem of during replacing crystalloid fluid.Meanwhile by switching the 6th with tubing clamp 98 Pipeline 6 bifurcated pipeline changes 4:The switching of the high potassium of 1 myocardium protecting liquid and low potassium liquid avoids the operation that contact pin 92 is pulled out, inserted.
As common pipeline connection type, female Luer 96 is provided on preferably the 4th pipeline 4, so as to oxygenator phase Connection, to provide oxygenated blood for clinical operation.In one embodiment, third pipeline 3 passes through female Luer with platform upper tube 7 96 or two-way joint 96 be connected.Since certain oxygenators (such as Medos, Dideco, Maquet etc.) itself are configured with Rule Connector, therefore the female Luer to match is set on the 4th pipeline 4 can easily realize connection.
Unlike the prior art, in myocardial protective liquid filling device 9 of the present invention due to more bifurcated return circuit modules 8, Number of tubes is relatively more, needs to flow through pipeline to crystalloid fluid and blood flows through pipeline and does and clearly distinguishes, avoid confusion as possible.In order to It avoids doctor in operation fast resolution first pipe 1 and second pipe 2, can make the color of first pipe 1 and branch 1 It is different from the color of second pipe 2 and branch 2 82.
Alternatively, the color of these pipelines it is identical or close in the case of, can be by a kind of color Labeling is fixed in first pipe 1 and branch 1, and the labeling of another color is fixed on second pipe 2 and branch 2 82 On, to which two lines road be distinguished.
For the ease of the connection of each pipeline to each other, three-way connection (or threeway) can be used between three pipelines 97, such as, Y shape threeway 97 is attached.The size of threeway 97 and the diameter dimension of each pipeline match.Such as first pipe Back segment 12, second pipe back segment 22 and third pipeline 3 are connected by a threeway 97.For example, when 1 internal diameter of first pipe is 1/ When 8 inches, second pipe 2 and 3 internal diameter of third pipeline are all 1/4 inch, one 1/4 × 1/4 × 1/8 (inch) can be used Y shape threeway.
Similarly, as shown in figures 2-6, second pipe leading portion 21, the 4th pipeline 4 and the 5th pipeline 5 are connected by one three First 97 are connected.First pipe leading portion 11, branch 1 and branch 3 83 are connected by a three-way connection 97, are located at a points; First pipe back segment 12, branch 1 and branch 4 84 are connected by a three-way connection 97, are located at b points;Before second pipe Section 21, branch 2 82 are connected with branch 4 84 by a three-way connection 97, and c points are located at;Second pipe back segment 22, branch two 82 are connected with branch 3 83 by a three-way connection, and d points are located at.
In one embodiment, first pipe leading portion 11, second pipe leading portion 21, third pipeline 3, the 4th pipeline 4, It is respectively equipped with tubing clamp 98 on five pipelines 5, branch 1, branch 2 82, branch 3 83 and branch 4 84, clamp can also be used Pincers replace, and to control the flowing of the liquid in each pipeline, realize the switching of a variety of myocardium protecting liquid reperfusion modes.
The myocardial protective liquid filling device 9 of the present invention can quickly and accurately complete a variety of perfusion switching modes, respectively It is described as follows.
Simple crystal perfusion
Referring to Fig. 2, when carrying out simple crystal perfusion, the tubing clamp 98 closed on second pipe leading portion 21 or make With gripping pliers clamping second pipe leading portion 21 (not shown), stop blood infusion, at this time under the driving of occlusion pump 93, monocrystalline body fluid It is managed from first pipe leading portion 11 along branch 1, branch 2 82, branch 3 83, branch 4 84, first pipe back segment 12, second Road back segment 22 meets at third pipeline 3 via occlusion pump 93, and is perfused to patient.Each branch 81- wherein in bifurcated return circuit module 8 Liquid flow direction in 84 is shown by arrow.
Hemoperfusion
Referring to Fig. 3, when carrying out hemoperfusion, the tubing clamp 98 closed on first pipe leading portion 11 or clamp is used Pincers clampings first pipe leading portion 11 (not shown) stops monocrystalline body fluid infusion, at this time in the case where occlusion pump 93 drives, oxygenated blood from Second pipe leading portion 21 is along branch 1, branch 2 82, branch 3 83, branch 4 84, first pipe back segment 12, second pipe Back segment 22 meets at third pipeline 3 via occlusion pump 93, and is perfused to patient.Each branch 81- wherein in bifurcated return circuit module 8 Liquid flow direction in 84 is shown by arrow.
Del Nido myocardium protecting liquid (blood:Crystal 1:4) it is perfused
Referring to Fig. 4, when progress del Nido myocardium protecting liquid (blood:Crystal 1:4) when being perfused, branch 1 and branch are closed It tubing clamp 98 on 2 82 or is clamped using gripping pliers is (not shown), at this time under the driving of occlusion pump 93, oxygenated blood is from second Pipeline leading portion 21 meets at third pipeline 3 by c points to b points, first pipe back segment 12 along branch 4 84 via occlusion pump 93;Together When, monocrystalline body fluid from first pipe leading portion 11 along branch 3 83 by a points to d points, second pipe back segment 22 via occlusion pump 93 Meet at third pipeline 3.Since oxygenated blood flow is monocrystal flow quantity in second pipe back segment 22 in first pipe back segment 12 A quarter, the myocardium protecting liquid in third pipeline 3 is blood:Crystal 1:4 protection liquid, to realize that del Nido cardiac muscles are protected Protect perfusion.Liquid flow direction in the branch 3 83 and branch 4 84 of bifurcated return circuit module 8 is shown by arrow.
Blood:Crystal 4:1 perfusion
Referring to Fig. 5, when into promoting circulation of blood:Crystal 4:1 myocardium protecting liquid (blood:Crystal 1:4) when being perfused, 3 83 He of branch is closed Tubing clamp 98 on branch 4 84 or clamped using gripping pliers is (not shown), at this time under the driving of occlusion pump 93, oxygenated blood from Second pipe leading portion 21 meets at third pipeline 3 along branch 2 82, second pipe back segment 22 via occlusion pump 93;Meanwhile it is single Crystalloid fluid meets at third pipeline along branch 1, first pipe back segment 12 from first pipe leading portion 11 via occlusion pump 93 3.Since monocrystal flow quantity is a quarter of oxygenated blood flow in second pipe back segment 22, third in first pipe back segment 12 Myocardium protecting liquid in pipeline 3 is blood:Crystal 4:1 protection liquid, to realize 4:1 perfusion of myocardial preservation containing blood.Bifurcated returns Liquid flow direction in the branch 1 and branch 2 82 of road module 8 is shown by arrow.
Reverse suck-back
Referring to Fig. 6 the 4th pipeline is closed when the suck-back that drive in the wrong direction is will pass through aortic root discharge heart intracavity gas 4 and the tubing clamp 98 on first pipe leading portion 11 or using gripping pliers it is (not shown) clamp.Then switch occlusion pump 93 Rotation direction, in the case where occlusion pump 93 rotates backward driving, gassiness blood is from platform upper tube 7 successively to after third pipeline 3, second pipe Section 22 and the flowing of 2 direction of second pipe, to which heart intracavity gas be discharged.Wherein in bifurcated return circuit module 8 in each branch 81-84 Liquid flow direction is shown by arrow.
Obviously, compared with currently used myocardial protective liquid filling device, myocardial protective liquid filling device 9 of the invention exists The replacement of crystalloid fluid is eliminated when use, as long as replacing pipeline presss from both sides closed position, so that it may to switch to required reperfusion mode, and Go out pipeline without closing pumping and exchanged, it is elastic also to readjust pump head 93, saves openheart surgery time out, and And reduce the workload of doctor.
Above-mentioned several embodiments show that myocardial protective liquid filling device 9 of the invention can be completed quickly and accurately Following 5 kinds of perfusions switching modes:A. blood (oxygenated blood) is perfused;B. blood:Crystal 4:1 perfusion;C. blood:Crystal 1:4 perfusions;D. Monocrystal is perfused;E. reverse suck-back blood.It has ensured the safety of myocardial preservation perfusion, and has been not likely to produce bubble.Even if Bubble is generated due to operation error also can continue to be perfused, and ensure that the safety of operation as far as possible.It is temporarily changed when in face of scene When reperfusion mode, doctor can operate without any confusion, reduce the chance of pollution and operation damage, and effectively save Operating time ensures that openheart surgery smoothly completes.The myocardial protective liquid filling device 9 of the present invention is in Fudan University is attached Mountain hospital heart surgical department is on probation, and handy and safe has obtained the consistent of operator and generally acknowledged.
Herein, the terms "include", "comprise" or any other variant thereof is intended to cover non-exclusive inclusion, from And make include a series of elements process, method, article or equipment not only including those elements, but also include not bright The other element really listed, or further include for elements inherent to such a process, method, article, or device.Do not having In the case of more limitations, the element that is limited by sentence "including a ...", it is not excluded that including the element process, Either there is also other identical or equivalent elements in equipment for method, article.
Myocardial protective liquid filling device provided herein is described in detail above, it is used herein specifically The principle and implementation of this application are described for a example, and the explanation of above example is only intended to help to understand the application Method and inventive concept;Meanwhile for those of ordinary skill in the art, according to the thought of the application, in specific embodiment party There will be changes in formula and application range, in conclusion the contents of this specification should not be construed as limiting the present application.

Claims (10)

1. a kind of myocardial protective liquid filling device comprising:First pipe for being transfused crystal myocardium protecting liquid, first pipe It is divided into first pipe leading portion and first pipe back segment;For the second pipe of infused blood, before second pipe is divided into second pipe Section and second pipe back segment;With after occlusion pump first pipe back segment and second pipe back segment unicom, for realizing the crystal heart Flesh protection liquid mixes with blood, is transfused the third pipeline of myocardium protecting liquid;For connecting second pipe leading portion and oxygenator Four pipelines;For connecting second pipe leading portion and storing up the 5th pipeline of blood tank;One end and first pipe leading portion be connected the 6th Pipeline;The platform upper tube being connected with third pipeline;The bifurcated return circuit module mutually switched for realizing first pipe and second pipe; It is set to the bubble filter of the 6th pipeline other end;The crystal myocardium protecting liquid contact pin being connected with bubble filter;For driving The occlusion pump of liquid flowing in dynamic first pipe and second pipe;Cooling tube on third pipeline, wherein
The bifurcated return circuit module is substantially in the figure of eight comprising:Both ends respectively with first pipe leading portion and first pipe back segment The branch one of unicom, the both ends branch two with second pipe leading portion and second pipe back segment unicom respectively, both ends are respectively with first The branch three of pipeline leading portion and second pipe back segment unicom, both ends respectively with second pipe leading portion and first pipe back segment unicom Branch four, wherein branch three intersect with branch four;
The inner hole section product of first pipe back segment is a quarter that the inner hole section of second pipe back segment accumulates.
2. myocardial protective liquid filling device as described in claim 1, which is characterized in that the 6th tube furcation is two, And respectively with a bubble filter unicom, each bubble filter is connected with a crystal myocardium protecting liquid contact pin respectively.
3. myocardial protective liquid filling device as described in claim 1, which is characterized in that be provided with Rule on the 4th pipeline and connect Head.
4. myocardial protective liquid filling device as described in claim 1, which is characterized in that third pipeline passes through Rule with platform upper tube Connector or two-way joint are connected.
5. myocardial protective liquid filling device as described in claim 1, which is characterized in that first pipe and the color of branch one with Second pipe is different with the color of branch two;Or a kind of labeling of color is fixed in first pipe and branch one, and incite somebody to action The labeling of another color is fixed on second pipe and branch two, to distinguish two lines road.
6. myocardial protective liquid filling device as described in claim 1, which is characterized in that after first pipe back segment, second pipe Section is connected with third pipeline by a three-way connection.
7. myocardial protective liquid filling device as described in claim 1, which is characterized in that second pipe leading portion, the 4th pipeline and 5th pipeline is connected by a three-way connection.
8. myocardial protective liquid filling device as described in claim 1, which is characterized in that first pipe leading portion, branch one and branch Road three is connected by a three-way connection;First pipe back segment, branch one and branch four are connected by a three-way connection; Second pipe leading portion, branch two and branch four are connected by a three-way connection;Second pipe back segment, branch two and branch three It is connected by a three-way connection.
9. myocardial protective liquid filling device as described in claim 1, which is characterized in that on third pipeline after cooling tube It is provided with bubble trap.
10. myocardial protective liquid filling device as described in claim 1, which is characterized in that first pipe internal diameter is second pipe The 1/2 of internal diameter.
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