CN108333440A - pulse detecting method and device - Google Patents
pulse detecting method and device Download PDFInfo
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- CN108333440A CN108333440A CN201711486351.8A CN201711486351A CN108333440A CN 108333440 A CN108333440 A CN 108333440A CN 201711486351 A CN201711486351 A CN 201711486351A CN 108333440 A CN108333440 A CN 108333440A
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
- G01R29/00—Arrangements for measuring or indicating electric quantities not covered by groups G01R19/00 - G01R27/00
- G01R29/02—Measuring characteristics of individual pulses, e.g. deviation from pulse flatness, rise time or duration
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Abstract
The present invention relates to a kind of pulse detecting method and device, the pulse detecting method includes the following steps：(A1) unbalanced pulse detector acquires original analog；(A2) analog signal is subjected to phase offset；(A3) analog signal is subjected to signal decaying；(A4) it is superimposed bias voltage, the bias voltage is greater than or equal to the maximum value of noise signal；(A5) original analog obtains number of pulses with through above-mentioned steps treated analog signal through step-by-step counting.The advantages that there is the present invention detection signal stabilization, no pulse to lose, and pulse detection automatically adjusts.
Description
Technical field
The present invention relates to mass spectral analysis fields, more particularly to a kind of pulse detection side applied to mass spectrograph pulse detector
Method and device.
Background technology
Pulse detector is widely used in mass spectrometric ion detection, by the analog pulse for detecting pulse detector output
Quantity reaches the amount of ions of detector entrance to obtain.When one ionic bombardment is to pulse detector, detector can be corresponding
A pulse low current signal is exported, usually tens nA to tens uA, pulse width is in tens nS.Under normal circumstances
One pulse signal, one ion generates, but in practical applications, not all ion is all to reach inspection in order
Device is surveyed, i.e., not all quasi-molecular ions is arranged in order, many times, when especially sample concentration is relatively high, very much
The time that ion reaches detector is very close, so the quasi-molecular ions formed is overlapping, a pulse signal represents not
It is an ion, prodigious difficulty is caused to the detection of signal and processing in this way.Also it is that quasi-molecular ions itself does not have to have a kind of situation
There is overlapping, but overlap peak is caused when carrying out signal enhanced processing, final or None- identified goes out two quasi-molecular ions, leads to pulse
It loses, testing result is inaccurate.
Invention content
In order to solve the deficiency in above-mentioned prior art, the present invention provides a kind of Ion Counting is accurate, it is ensured that arteries and veins
Punching is not lost, and detection signal stabilization, at low cost automatically adjusts the pulse detecting method and device of pulse detection.
The purpose of the present invention is what is be achieved through the following technical solutions：
A kind of pulse detecting method, the pulse detecting method include the following steps：
(A1) unbalanced pulse detector, acquires original analog, and the original analog is to convert and amplify through I-V
Analog signal afterwards；
(A2) analog signal is subjected to phase offset；
(A3) analog signal is subjected to signal decaying；
(A4) it is superimposed bias voltage, the bias voltage is greater than or equal to the maximum value of noise signal；
(A5) original analog obtains arteries and veins with through above-mentioned steps treated analog signal through step-by-step counting
Rush quantity.
According to above-mentioned pulse detecting method, it is preferable that the pulse detecting method is further comprising the steps of：
(B1) Regulate signal attenuation amplitude obtains maximum impulse quantity, completes automatic adjustment.
According to above-mentioned pulse detecting method, optionally, phase offset ranging from deviates to the right 1/4 analog signal peak width
To 1/2 analog signal peak width.
According to above-mentioned pulse detecting method, it is preferable that the bias voltage is obtained by following steps：
(C1) pulse detector is closed, bias voltage is gradually increased since 0V, voltage when number of pulses is 0 is biasing
Voltage；
Step (C1) is located at before step (A1).
According to above-mentioned pulse detecting method, optionally, (A3) step is located at before (A2) step.
According to above-mentioned pulse detecting method, optionally, (A4) step is between (A1) and (A2).
The present invention also provides a kind of pulse detecting equipment, the pulse detecting equipment includes：
Sequentially connected pulse detector, I-V conversion circuits, signal amplification circuit, impedance matching network, pulse counter
And display：
Phase offset circuit, the input terminal of the phase offset circuit connect the output end of the signal amplification circuit, use
In the phase offset of analog signal；
Signal attenuation circuit, the input terminal connection phase offset circuit of the signal attenuation circuit, output end connecting valve,
Decaying for analog signal；
Switch, the switch are arranged between the signal attenuation circuit and bias voltage output circuit；
Bias voltage output circuit, for exporting bias voltage, the bias voltage and the analog signal after offset, decaying
Analog-to-digital comparison circuit is transmitted to after superposition；
Analog-to-digital comparison circuit, the analog-to-digital comparison circuit are arranged in signal amplification circuit and impedance matching
Between network, for comparing original analog and the analog signal after offset, decaying, superposition bias voltage, and then obtain
Number of pulses；
Control unit, described control unit for control it is described switch on-off, the amplitude and mould of the bias voltage
The attenuation amplitude of quasi- signal.
According to above-mentioned pulse detecting equipment, optionally, the phase offset circuit is capacitance.
According to above-mentioned pulse detecting equipment, it is preferable that the attenuation amplitude of the signal attenuation circuit is adjustable, control unit
The number of pulses that pulse counter provides is received, the amplitude of signal decaying is adjusted, when number of pulses maximum, is completed certainly
It is dynamic to adjust.
According to above-mentioned pulse detecting equipment, optionally, the signal attenuation circuit includes digital analog converter, operation amplifier
Device and resistance.
Compared with prior art, the device have the advantages that being：
1, the present invention carries out phase offset, signal decaying and and DC offset voltage to amplified original analog
Overlap-add procedure after, then be compared counting with original analog, realize the counting to all ions, it is ensured that pulse is not lost
It loses.
2, number of pulses is fed back to control unit by pulse counter of the invention, by control unit to bias voltage,
Switch and signal attenuation circuit automatic adjustment are adjusted quick and precisely to obtain maximum impulse quantity.
3, pulse detecting method of the invention can reduce the bandwidth of pulse detector output signal amplification circuit, ensure letter
Number detection stability, reduce cost.
Description of the drawings
With reference to attached drawing, the disclosure will be easier to understand.Skilled addressee readily understands that be：This
A little attached drawings are used only for the technical solution illustrated the present invention, and are not intended to and are construed as limiting to protection scope of the present invention.
In figure：
Fig. 1 is the electrical block diagram of the pulse detecting equipment of the embodiment of the present invention 1；
Fig. 2 is the signal attenuation circuit structural schematic diagram of the pulse detecting equipment of the embodiment of the present invention 2；
Fig. 3 is the pulse detection automatic adjustment flow chart of the embodiment of the present invention 2.
Embodiment
Fig. 1-3 and following description describe the present invention optional embodiment to instruct how those skilled in the art implement
It is of the invention with reproducing.In order to instruct technical solution of the present invention, some conventional aspects are simplified or have been omitted.Those skilled in the art
It should be appreciated that modification or replacement from these embodiments will within the scope of the invention.Those skilled in the art should understand that
Following characteristics can be combined in various ways to form multiple modifications of the present invention.As a result, the invention is not limited in it is following can
Embodiment, and be only limited by the claims and their equivalents.
Embodiment 1
Fig. 1 schematically illustrates the circuit structure schematic diagram of the pulse detecting equipment of the present embodiment, as shown in Figure 1：It is described
Pulse detecting equipment includes：
Sequentially connected pulse detector, I-V conversion circuits, signal amplification circuit, impedance matching network, pulse counter
And display：
Phase offset circuit, the input terminal of the phase offset circuit connect the output end of the signal amplification circuit, use
In the phase offset of analog signal；
Signal attenuation circuit, the input terminal connection phase offset circuit of the signal attenuation circuit, output end connecting valve,
Decaying for analog signal；
Switch, the switch are arranged between the signal attenuation circuit and bias voltage output circuit；
Bias voltage output circuit, for exporting bias voltage, the bias voltage and the analog signal after offset, decaying
Analog-to-digital comparison circuit is transmitted to after superposition；
Analog-to-digital comparison circuit, the analog-to-digital comparison circuit are arranged in signal amplification circuit and impedance matching
Between network, for comparing original analog and the analog signal after offset, decaying, superposition bias voltage, and then obtain
Number of pulses；
Control unit, described control unit for control it is described switch on-off, the amplitude and mould of the bias voltage
The attenuation amplitude of quasi- signal.
Above-mentioned pulse detector, I-V conversion circuits, signal amplification circuit, impedance matching network, pulse counter and display
Device is the prior art, and details are not described herein.
In order to ensure pulse is not lost, the maximum count of number of pulses is realized, therefore：
Further, the attenuation amplitude of the signal attenuation circuit is adjustable, and control unit receives what pulse counter provided
The amplitude of signal decaying is adjusted in number of pulses, when number of pulses maximum, completes automatic adjustment.
The present embodiment also provides a kind of pulse detecting method of above-mentioned pulse detecting equipment, and the pulse detecting method includes
Following steps：
(A1) unbalanced pulse detector, acquires original analog, and the original analog is to turn through I-V conversion circuits
It changes, through the amplified analog signal of signal amplification circuit；
(A2) analog signal is subjected to phase offset；
(A3) analog signal is subjected to signal decaying；
(A4) it is superimposed bias voltage, the bias voltage is greater than or equal to the maximum value of noise signal；
(A5) original analog obtains arteries and veins with through above-mentioned steps treated analog signal through step-by-step counting
Rush quantity.
There are noise signals for pulse-detecting circuit itself, count noise signal when to avoid step-by-step counting, thus
Bias voltage is set, will be compared again with original analog after bias voltage and the analog signal superposition after offset, decaying
It counts, you can exclude noise signal.Therefore, bias voltage need to be more than the maximum value of noise signal, and minimum bias voltage in order is maximum
Noise signal.
The signal attenuation amplitude pulse count of analog signal impacts, to ensure that the analog signal of overlapping is not lost,
The counting of all pulses is realized, while in order to realize the automatic adjustment of pulse detection, in pulse counter and control unit, signal
Feedback regulation is set between attenuator circuit, therefore：
Further, the pulse detecting method is further comprising the steps of：
(B1) number of pulses of control unit reception pulse counter, the signal attenuation amplitude of Regulate signal attenuator circuit,
When obtaining maximum impulse quantity, automatic adjustment is completed.
The phase offset amplitude of analog signal cannot be excessive, it is necessary to assure same signal peak after offset there are still overlapping,
In order to improve the accuracy of step-by-step counting, therefore：
Further, phase offset ranging from deviates to the right 1/4 analog signal peak width to 1/2 analog signal peak width.
When to analog signal processing, it can first decay and deviate afterwards, therefore, (A3) step can be located at before (A2) step.Together
Sample, the offset and decaying of signal are carried out after can also being first superimposed original analog with bias voltage again, therefore, (A4) step
It suddenly can be between (A1) and (A2).
The present embodiment is had an advantage that：Phase offset, signal decaying and and direct current biasing are carried out to original analog
It is compared counting after the overlap-add procedure of voltage with original analog again, while number of pulses amount carries out feedback regulation, realizes
The automatic adjustment of pulse detection, step-by-step counting are accurate.
Embodiment 2
The present embodiment is application examples of the pulse detecting equipment of the embodiment of the present invention 1 on mass spectrograph.
In the application examples, circuit is impacted to avoid pulse detector from opening the instantaneous high pressure that moment generates,
Overvoltage crowbar is set between pulse detector and I-V conversion circuits；Phase offset circuit is capacitance, signal attenuation circuit packet
Digital analog converter, operational amplifier and resistance (as shown in Figure 2) are included, it can be to decaying by control unit (using MCU) control DAC
Amplitude is adjusted.
Fig. 3 schematically illustrates pulse detection automatic adjustment flow chart, as shown in figure 3, pulse detecting equipment is automatic
Regulation flow process is as follows：
S1. pulse detector is closed, switch is disconnected, bias voltage, electricity when number of pulses is 0 are gradually increased since 0V
Pressure is bias voltage；
S2. unbalanced pulse detector turns on the switch, and acquires original analog；
S3. analog signal is subjected to phase offset, signal decays, and is transmitted to analog-to-digital ratio after being superimposed bias voltage
Compared with circuit；
S4. number of pulses is fed back to control unit by pulse counter, and signal attenuation amplitude is adjusted in control unit；
S5. when number of pulses reaches maximum, automatic adjustment is completed.
Claims (10)
1. a kind of pulse detecting method, it is characterised in that：The pulse detecting method includes the following steps：
(A1) unbalanced pulse detector acquires original analog；
(A2) analog signal is subjected to phase offset；
(A3) analog signal is subjected to signal decaying；
(A4) it is superimposed bias voltage, the bias voltage is greater than or equal to the maximum value of noise signal；
(A5) original analog obtains umber of pulse with through above-mentioned steps treated analog signal through step-by-step counting
Amount.
2. pulse detecting method according to claim 1, it is characterised in that：The pulse detecting method further comprise with
Lower step：
(B1) Regulate signal attenuation amplitude obtains maximum impulse quantity, completes automatic adjustment.
3. pulse detecting method according to claim 2, it is characterised in that：Phase offset ranging from deviates to the right 1/4
Analog signal peak width is to 1/2 analog signal peak width.
4. pulse detecting method according to claim 1, it is characterised in that：The bias voltage is obtained by following steps
：
(C1) pulse detector is closed, bias voltage is gradually increased since 0V, voltage when number of pulses is 0 is biased electrical
Pressure；
Step (C1) is located at before step (A1).
5. pulse detecting method according to claim 1, it is characterised in that：(A3) step is located at before (A2) step.
6. pulse detecting method according to claim 1, it is characterised in that：(A4) step is between (A1) and (A2).
7. a kind of pulse detecting equipment, including sequentially connected pulse detector, I-V conversion circuits, signal amplification circuit, impedance
Matching network, pulse counter and display, it is characterised in that：The pulse detecting equipment further comprises：
Phase offset circuit, the input terminal of the phase offset circuit connect the output end of the signal amplification circuit, are used for mould
The phase offset of quasi- signal；
The input terminal of signal attenuation circuit, the signal attenuation circuit connects phase offset circuit, and output end connecting valve is used for
The decaying of analog signal；
Switch, the switch are arranged between the signal attenuation circuit and bias voltage output circuit；
Bias voltage output circuit, for exporting bias voltage, the bias voltage is superimposed with the analog signal after offset, decaying
After be transmitted to analog-to-digital comparison circuit；
Analog-to-digital comparison circuit, the analog-to-digital comparison circuit are arranged in signal amplification circuit and impedance matching network
Between, for comparing original analog and the analog signal after offset, decaying, superposition bias voltage, and then obtain pulse
Quantity；
Control unit, described control unit for control it is described switch on-off, the amplitude and simulation letter of the bias voltage
Number attenuation amplitude.
8. pulse detecting equipment according to claim 7, it is characterised in that：The phase offset circuit is capacitance.
9. pulse detecting equipment according to claim 7, it is characterised in that：The attenuation amplitude of the signal attenuation circuit can
It adjusts, control unit receives the number of pulses that pulse counter provides, and the amplitude of signal decaying is adjusted.
10. pulse detecting equipment according to claim 9, it is characterised in that：The signal attenuation circuit includes that digital-to-analogue turns
Parallel operation, operational amplifier and resistance.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201711486351.8A CN108333440B (en) | 2017-12-30 | 2017-12-30 | Pulse detection method and device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201711486351.8A CN108333440B (en) | 2017-12-30 | 2017-12-30 | Pulse detection method and device |
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| Publication Number | Publication Date |
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| CN108333440A true CN108333440A (en) | 2018-07-27 |
| CN108333440B CN108333440B (en) | 2021-02-12 |
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ID=62923807
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| CN201711486351.8A Active CN108333440B (en) | 2017-12-30 | 2017-12-30 | Pulse detection method and device |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114089036A (en) * | 2021-11-09 | 2022-02-25 | 许继集团有限公司 | Key phase pulse intelligent acquisition device and acquisition method thereof |
| CN117434820A (en) * | 2023-12-19 | 2024-01-23 | 杭州谱育科技发展有限公司 | Time-to-digital converter and time-of-flight mass spectrometer |
| CN117434820B (en) * | 2023-12-19 | 2024-08-27 | 杭州谱育科技发展有限公司 | Time-to-digital converter and time-of-flight mass spectrometer |
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| CN86103646A (en) * | 1985-05-31 | 1986-11-26 | 科特电子有限公司 | The clipping method and the device of the electric pulse that particle produces |
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114089036A (en) * | 2021-11-09 | 2022-02-25 | 许继集团有限公司 | Key phase pulse intelligent acquisition device and acquisition method thereof |
| CN114089036B (en) * | 2021-11-09 | 2024-04-16 | 许继集团有限公司 | Key phase pulse intelligent acquisition device and acquisition method thereof |
| CN117434820A (en) * | 2023-12-19 | 2024-01-23 | 杭州谱育科技发展有限公司 | Time-to-digital converter and time-of-flight mass spectrometer |
| CN117434820B (en) * | 2023-12-19 | 2024-08-27 | 杭州谱育科技发展有限公司 | Time-to-digital converter and time-of-flight mass spectrometer |
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| CN108333440B (en) | 2021-02-12 |
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Effective date of registration: 20210621 Address after: Hangzhou City, Zhejiang province Binjiang District 310052 shore road 760 Patentee after: Concentrating Technology (Hangzhou) Co.,Ltd. Patentee after: HANGZHOU PUYU TECHNOLOGY DEVELOPMENT Co.,Ltd. Patentee after: Hangzhou puju Medical Technology Co.,Ltd. Address before: Hangzhou City, Zhejiang province Binjiang District 310052 shore road 760 Patentee before: Concentrating Technology (Hangzhou) Co.,Ltd. Patentee before: HANGZHOU PUYU TECHNOLOGY DEVELOPMENT Co.,Ltd. |
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