CN108324673A - A kind of face mesenchyma is against age method for customizing - Google Patents

A kind of face mesenchyma is against age method for customizing Download PDF

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Publication number
CN108324673A
CN108324673A CN201810115675.9A CN201810115675A CN108324673A CN 108324673 A CN108324673 A CN 108324673A CN 201810115675 A CN201810115675 A CN 201810115675A CN 108324673 A CN108324673 A CN 108324673A
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face
skin
filler
facial
collagen
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Inventor
邵利
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Ningbo Dongqian Lake Holiday Resort Jingrui Medical Beauty Clinic Co Ltd
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Ningbo Dongqian Lake Holiday Resort Jingrui Medical Beauty Clinic Co Ltd
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Priority to CN201810115675.9A priority Critical patent/CN108324673A/en
Publication of CN108324673A publication Critical patent/CN108324673A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64Proteins; Peptides; Derivatives or degradation products thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64Proteins; Peptides; Derivatives or degradation products thereof
    • A61K8/65Collagen; Gelatin; Keratin; Derivatives or degradation products thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
    • A61K8/735Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/81Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
    • A61K8/8141Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides or nitriles thereof; Compositions of derivatives of such polymers
    • A61K8/8152Homopolymers or copolymers of esters, e.g. (meth)acrylic acid esters; Compositions of derivatives of such polymers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/99Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from microorganisms other than algae or fungi, e.g. protozoa or bacteria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/08Anti-ageing preparations

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Birds (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Gerontology & Geriatric Medicine (AREA)
  • Dermatology (AREA)
  • Materials For Medical Uses (AREA)
  • Medicinal Preparation (AREA)

Abstract

The invention discloses a kind of facial mesenchymas against age method for customizing, includes the following steps:Step 1:Face is detected using skin detection instrument, the state of skin is detected, then orients position to be processed, step 2 needed for skin:Face is scanned using 3D scanning techniques, records the data information of face, step 3:Compared with the inverse age face template recorded according to the data information at each position of face, find most close to template planned.The present invention can not only quickly detect the skin of face, and the three-dimensional image of scanning face, contrast mould finds the minimum template of immediate filling and carries out comparison filling, and extra fat can not only be cut down and placenta CD106 positives mescenchymal stem cell can promote angiogenesis using botulin toxin by filling, the reparation of cell, avoid cutis laxa, the stimulating method of last electroacupumcture can promote stem cell to discharge, keep skin younger, really realizes skin against age growth.

Description

A kind of face mesenchyma is against age method for customizing
Technical field
The present invention relates to facial mesenchymas against age method for customizing field, more particularly to a kind of facial mesenchyma is against age customization side Method.
Background technology
The reduction of fibroblast number, deterioration after skin aging, skin collagen, hyaluronic acid synthesis are reduced, collagen, Elastic fibrosis aging is that skin aging atrophy is thinning, the main reason for wrinkle occurs.For wrinkle of skin, mainly have at present Two kinds of approach, operation smoothing wrinkle and injection smoothing wrinkle.Wrinkle improvement effect of performing the operation is definite, but risk is high, complication is more, common people's receptance It is low.Injection smoothing wrinkle mainly has two methods of injection botulinum toxin and injection molding process object, but in existing fill method, for very More people have facial stiff or facial filling excessive, cause facial unnatural, the case where not liking of consumer.
Therefore, a kind of facial mesenchyma of invention solves the above problems necessary against age method for customizing.
Invention content
The purpose of the present invention is to provide a kind of facial mesenchymas against age method for customizing, to solve to carry in above-mentioned background technology The problem of going out.
To achieve the above object, the present invention provides the following technical solutions:It is a kind of face mesenchyma against age method for customizing, including Following steps:
Step 1:Face is detected using skin detection instrument, detects the state of skin, then orients place required for skin The position of reason;
Step 2:Face is scanned using 3D scanning techniques, records the data information of face;
Step 3:It is compared according to the inverse age face template of the data information and record at each position of face, finds and most paste Close template is planned;
Step 4:The numerical value at each position and the wanted gap of template is calculated using computer technology, and produces gap Numerical value;
Step 5:Doctor is planned according to data difference to be filled or the position cut down and thickness, by face into Line flag, and record the disposition done required for the position;
Step 6:Rational filler is proposed according to the position of required adjustment, for the position that needs are cut down, is prepared Filler one prepares filler two for the position that needs are filled;
Step 7:Prepare filler one:Prepare placenta CD106 positives mescenchymal stem cell, botulin toxin, collagen egg In vain, poly (methyl methacrylate) micro-sphere, lidocaine and hyaluronic acid, botulin toxin are diluted with sterile saline, are mixed Injection needs the facial cut down after conjunction;
Step 8:Prepare filler two:Prepare placenta CD106 positives mescenchymal stem cell, fibroblast growth factor, collagen egg In vain, poly (methyl methacrylate) micro-sphere, lidocaine, elastomer, epidermal growth factor, tyrosinase inhibiting factor, sheep placenta Element, sodium hyaluronate, FOXO3a and FOXO1, the facial that injection needs are filled after then mixing;
Step 9:After the completion of injection, the method that the position of a crease in the skin recycles electroacupuncture stimulates brain, promotes prosthetic Mescenchymal stem cell be discharged into blood, to excite the curative of stem cell, electroacupuncture stem cell can be made at 9 to 22 minutes Interior activation hypothalamus, and be discharged into blood within 2 hours.
Preferably, placenta CD106 positive mescenchymal stem cells in the filler one:Botulin toxin:Collagen:It is poly- Methyl methacrylate microballoon:Lidocaine:Hyaluronic acid=6-8:10-12:2:0.5:0.007:3-5.
Preferably, prepare placenta CD106 positive mescenchymal stem cells in the filler two:Fibroblast growth factor:Collagen Albumen:Poly (methyl methacrylate) micro-sphere:Lidocaine:Elastomer:Epidermal growth factor:Tyrosinase inhibiting factor:Sheep Tire element:Sodium hyaluronate:FOXO3a:FOXO1=10-12:1-3:2-4:0.5:0.007:0.6-0.8:0.4-0.6:0.02:0.8-1: 1.2-1.4:0.4-0.6:0.5-0.8.
The technique effect and advantage of the present invention:By such method for customizing, the skin shape of face can not only be quickly detected Condition, and the three-dimensional image of face is scanned, contrast mould finds the minimum template of immediate filling and carries out comparison filling, And extra fat and placenta CD106 positive mescenchymal stem cell energy can not only be cut down using botulin toxin by filling Angiogenesis, the reparation of cell is enough promoted to avoid cutis laxa, collagen, poly (methyl methacrylate) micro-sphere and benefit card The setting of cause can play a supporting role to collagen, so that filling is held time longer, and FOXO3a and FOXO1 can speed up original Beginning ovarian follicle activate and granulosa cell proliferation, the stimulating method of last electroacupumcture stem cell can be promoted to discharge, filling effect more preferably, Keep skin younger, really realizes skin against age growth.
Specific implementation mode
Below in conjunction with the embodiment of the present invention, technical solution in the embodiment of the present invention is clearly and completely retouched It states, it is clear that described embodiments are only a part of the embodiments of the present invention, instead of all the embodiments.Based on the present invention In embodiment, every other implementation obtained by those of ordinary skill in the art without making creative efforts Example, shall fall within the protection scope of the present invention.
Embodiment 1:
The present invention provides a kind of facial mesenchymas against age method for customizing, includes the following steps:
Step 1:Face is detected using skin detection instrument, detects the state of skin, then orients place required for skin The position of reason;
Step 2:Face is scanned using 3D scanning techniques, records the data information of face;
Step 3:It is compared according to the inverse age face template of the data information and record at each position of face, finds and most paste Close template is planned;
Step 4:The numerical value at each position and the wanted gap of template is calculated using computer technology, and produces gap Numerical value;
Step 5:Doctor is planned according to data difference to be filled or the position cut down and thickness, by face into Line flag, and record the disposition done required for the position;
Step 6:Rational filler is proposed according to the position of required adjustment, for the position that needs are cut down, is prepared Filler one prepares filler two for the position that needs are filled;
Step 7:Prepare filler one:Prepare placenta CD106 positives mescenchymal stem cell, botulin toxin, collagen egg In vain, poly (methyl methacrylate) micro-sphere, lidocaine and hyaluronic acid, botulin toxin are diluted with sterile saline, are mixed Injection needs the facial cut down after conjunction, placenta CD106 positive mescenchymal stem cells in the filler one:Clostridium botulinum poison Element:Collagen:Poly (methyl methacrylate) micro-sphere:Lidocaine:Hyaluronic acid=6:12:2:0.5:0.007:5;
Step 8:Prepare filler two:Prepare placenta CD106 positives mescenchymal stem cell, fibroblast growth factor, collagen egg In vain, poly (methyl methacrylate) micro-sphere, lidocaine, elastomer, epidermal growth factor, tyrosinase inhibiting factor, sheep placenta Element, sodium hyaluronate, FOXO3a and FOXO1 inject the facial for needing to fill, prepare placenta in the filler two after then mixing CD106 positive mescenchymal stem cells:Fibroblast growth factor:Collagen:Poly (methyl methacrylate) micro-sphere:Lidocaine: Elastomer:Epidermal growth factor:Tyrosinase inhibiting factor:Sheep placenta:Sodium hyaluronate:FOXO3a:FOXO1=10:3:2: 0.5:0.007:0.8:0.4:0.02:1:1.2:0.6:0.5, collagen, poly (methyl methacrylate) micro-sphere and lidocaine Setting can play a supporting role to collagen, so that filling is held time longer, FOXO3a and FOXO1 can speed up original Ovarian follicle activates and granulosa cell proliferation;
Step 9:After the completion of injection, the method that the position of a crease in the skin recycles electroacupuncture stimulates brain, promotes prosthetic Mescenchymal stem cell be discharged into blood, to excite the curative of stem cell, electroacupuncture stem cell can be made at 9 to 22 minutes Interior activation hypothalamus, and be discharged into blood within 2 hours.
Embodiment 2:
The present invention provides a kind of facial mesenchymas against age method for customizing, includes the following steps:
Step 1:Face is detected using skin detection instrument, detects the state of skin, then orients place required for skin The position of reason;
Step 2:Face is scanned using 3D scanning techniques, records the data information of face;
Step 3:It is compared according to the inverse age face template of the data information and record at each position of face, finds and most paste Close template is planned;
Step 4:The numerical value at each position and the wanted gap of template is calculated using computer technology, and produces gap Numerical value;
Step 5:Doctor is planned according to data difference to be filled or the position cut down and thickness, by face into Line flag, and record the disposition done required for the position;
Step 6:Rational filler is proposed according to the position of required adjustment, for the position that needs are cut down, is prepared Filler one prepares filler two for the position that needs are filled;
Step 7:Prepare filler one:Prepare placenta CD106 positives mescenchymal stem cell, botulin toxin, collagen egg In vain, poly (methyl methacrylate) micro-sphere, lidocaine and hyaluronic acid, botulin toxin are diluted with sterile saline, are mixed Injection needs the facial cut down after conjunction, placenta CD106 positive mescenchymal stem cells in the filler one:Clostridium botulinum poison Element:Collagen:Poly (methyl methacrylate) micro-sphere:Lidocaine:Hyaluronic acid=7:11:2:0.5:0.007:4;
Step 8:Prepare filler two:Prepare placenta CD106 positives mescenchymal stem cell, fibroblast growth factor, collagen egg In vain, poly (methyl methacrylate) micro-sphere, lidocaine, elastomer, epidermal growth factor, tyrosinase inhibiting factor, sheep placenta Element, sodium hyaluronate, FOXO3a and FOXO1 inject the facial for needing to fill, prepare placenta in the filler two after then mixing CD106 positive mescenchymal stem cells:Fibroblast growth factor:Collagen:Poly (methyl methacrylate) micro-sphere:Lidocaine: Elastomer:Epidermal growth factor:Tyrosinase inhibiting factor:Sheep placenta:Sodium hyaluronate:FOXO3a:FOXO1=11:2:3: 0.5:0.007:0.7:0.5:0.02:0.9:1.3:0.5:0.65, collagen, poly (methyl methacrylate) micro-sphere and benefit card The setting of cause can play a supporting role to collagen, so that filling is held time longer, and FOXO3a and FOXO1 can speed up original Beginning ovarian follicle activates and granulosa cell proliferation;
Step 9:After the completion of injection, the method that the position of a crease in the skin recycles electroacupuncture stimulates brain, promotes prosthetic Mescenchymal stem cell be discharged into blood, to excite the curative of stem cell, electroacupuncture stem cell can be made at 9 to 22 minutes Interior activation hypothalamus, and be discharged into blood within 2 hours.
Embodiment 3:
The present invention provides a kind of facial mesenchymas against age method for customizing, includes the following steps:
Step 1:Face is detected using skin detection instrument, detects the state of skin, then orients place required for skin The position of reason;
Step 2:Face is scanned using 3D scanning techniques, records the data information of face;
Step 3:It is compared according to the inverse age face template of the data information and record at each position of face, finds and most paste Close template is planned;
Step 4:The numerical value at each position and the wanted gap of template is calculated using computer technology, and produces gap Numerical value;
Step 5:Doctor is planned according to data difference to be filled or the position cut down and thickness, by face into Line flag, and record the disposition done required for the position;
Step 6:Rational filler is proposed according to the position of required adjustment, for the position that needs are cut down, is prepared Filler one prepares filler two for the position that needs are filled;
Step 7:Prepare filler one:Prepare placenta CD106 positives mescenchymal stem cell, botulin toxin, collagen egg In vain, poly (methyl methacrylate) micro-sphere, lidocaine and hyaluronic acid, botulin toxin are diluted with sterile saline, are mixed Injection needs the facial cut down after conjunction, placenta CD106 positive mescenchymal stem cells in the filler one:Clostridium botulinum poison Element:Collagen:Poly (methyl methacrylate) micro-sphere:Lidocaine:Hyaluronic acid=8:10:2:0.5:0.007:5;
Step 8:Prepare filler two:Prepare placenta CD106 positives mescenchymal stem cell, fibroblast growth factor, collagen egg In vain, poly (methyl methacrylate) micro-sphere, lidocaine, elastomer, epidermal growth factor, tyrosinase inhibiting factor, sheep placenta Element, sodium hyaluronate, FOXO3a and FOXO1 inject the facial for needing to fill, prepare placenta in the filler two after then mixing CD106 positive mescenchymal stem cells:Fibroblast growth factor:Collagen:Poly (methyl methacrylate) micro-sphere:Lidocaine: Elastomer:Epidermal growth factor:Tyrosinase inhibiting factor:Sheep placenta:Sodium hyaluronate:FOXO3a:FOXO1=12:1:4: 0.5:0.007:0.6:0.6:0.02:0.8:1.4:0.4:0.8, collagen, poly (methyl methacrylate) micro-sphere and benefit card The setting of cause can play a supporting role to collagen, so that filling is held time longer, and FOXO3a and FOXO1 can speed up original Beginning ovarian follicle activates and granulosa cell proliferation;
Step 9:After the completion of injection, the method that the position of a crease in the skin recycles electroacupuncture stimulates brain, promotes prosthetic Mescenchymal stem cell be discharged into blood, to excite the curative of stem cell, electroacupuncture stem cell can be made at 9 to 22 minutes Interior activation hypothalamus, and be discharged into blood within 2 hours.
Learnt according to embodiment 1-3, each component ratio is relatively mild in embodiment 2, will not cause the waste of material and Filling effect is preferable, will not fill it is excessive or very few, cause face it is stiff, facial line is not smooth soft.
Finally it should be noted that:The foregoing is only a preferred embodiment of the present invention, is not intended to restrict the invention, Although the present invention is described in detail referring to the foregoing embodiments, for those skilled in the art, still may be used With technical scheme described in the above embodiments is modified or equivalent replacement of some of the technical features, All within the spirits and principles of the present invention, any modification, equivalent replacement, improvement and so on should be included in the present invention's Within protection domain.

Claims (3)

1. a kind of face mesenchyma is against age method for customizing, it is characterised in that:Include the following steps:
Step 1:Face is detected using skin detection instrument, the state of skin is detected, then orients to be processed needed for skin Position;
Step 2:Face is scanned using 3D scanning techniques, records the data information of face;
Step 3:Compared with the inverse age face template recorded according to the data information at each position of face, find most close to Template is planned;
Step 4:The numerical value at each position and the wanted gap of template is calculated using computer technology, and produces gap numerical value;
Step 5:Doctor is planned according to data difference to be filled or the position cut down and thickness, by face into rower Note, and record the disposition done required for the position;
Step 6:Rational filler is proposed according to the position of required adjustment, for the position that needs are cut down, prepares filler One, for the position that needs are filled, prepare filler two;
Step 7:Prepare filler one:Prepare placenta CD106 positives mescenchymal stem cell, botulin toxin, collagen, gather Methyl methacrylate microballoon, lidocaine and hyaluronic acid, botulin toxin are diluted with sterile saline, are noted after mixing Enter to need the facial cut down;
Step 8:Prepare filler two:Prepare placenta CD106 positives mescenchymal stem cells, fibroblast growth factor, collagen, Poly (methyl methacrylate) micro-sphere, lidocaine, elastomer, epidermal growth factor, tyrosinase inhibiting factor, sheep placenta, Sodium hyaluronate, FOXO3a and FOXO1, the facial that injection needs are filled after then mixing;
Step 9:After the completion of injection, the method that the position of a crease in the skin recycles electroacupuncture stimulates brain, promotes between prosthetic Mesenchymal stem cells are discharged into blood, to excite the curative of stem cell, electroacupuncture that stem cell can be made to swash in 9 to 22 minutes Hypothalamus living, and be discharged into blood within 2 hours.
2. a kind of facial mesenchyma according to claim 1 is against age method for customizing, it is characterised in that:Tire in the filler one Disk CD106 positive mescenchymal stem cells:Botulin toxin:Collagen:Poly (methyl methacrylate) micro-sphere:Lidocaine: Hyaluronic acid=6-8:10-12:2:0.5:0.007:3-5.
3. a kind of facial mesenchyma according to claim 1 is against age method for customizing, it is characterised in that:It is accurate in the filler two Spare tyre disk CD106 positive mescenchymal stem cells:Fibroblast growth factor:Collagen:Poly (methyl methacrylate) micro-sphere:Benefit Cacaine:Elastomer:Epidermal growth factor:Tyrosinase inhibiting factor:Sheep placenta:Sodium hyaluronate:FOXO3a:FOXO1=10- 12:1-3:2-4:0.5:0.007:0.6-0.8:0.4-0.6:0.02:0.8-1:1.2-1.4:0.4-0.6:0.5-0.8.
CN201810115675.9A 2018-02-06 2018-02-06 A kind of face mesenchyma is against age method for customizing Pending CN108324673A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111419780A (en) * 2020-05-07 2020-07-17 南京恒奥源医疗器械有限公司 Facial composition and application thereof

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111419780A (en) * 2020-05-07 2020-07-17 南京恒奥源医疗器械有限公司 Facial composition and application thereof

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Application publication date: 20180727