CN108310804A - Solid phase microextraction pre-treatment component and solid-phase micro-extracting device - Google Patents
Solid phase microextraction pre-treatment component and solid-phase micro-extracting device Download PDFInfo
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- CN108310804A CN108310804A CN201810284374.9A CN201810284374A CN108310804A CN 108310804 A CN108310804 A CN 108310804A CN 201810284374 A CN201810284374 A CN 201810284374A CN 108310804 A CN108310804 A CN 108310804A
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/10—Selective adsorption, e.g. chromatography characterised by constructional or operational features
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/10—Selective adsorption, e.g. chromatography characterised by constructional or operational features
- B01D15/14—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to the introduction of the feed to the apparatus
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Abstract
The present invention provides solid phase microextraction pre-treatment component and solid-phase micro-extracting devices, belong to trace samplings processing and analysis of volatile components technical field, solid phase microextraction pre-treatment component includes extraction flask and sample bottle, the extrusion structure for being equipped with the sample extruding for will be placed in it in sample bottle and squeezing out the object to be extracted in it, extraction flask is connected to sample bottle and the object to be extracted being extruded is enable to enter in extraction flask from sample bottle, extraction flask has the bottleneck passed through for extraction needle, the bottle mouth position is equipped with for the extraction flask sealing structure when extracting needle and being inserted into extraction flask with extraction needle sealing cooperation, the extrusion structure includes extrusion head and is relatively fixed the spinning structure of setting in the direction of extrusion with extrusion head.Sample is squeezed by rotary squeezing head, so that the object to be extracted overflowed in sample is entered in extraction flask and is adsorbed by the syringe needle of extraction needle, solves the problems, such as volatile ingredient can be caused to lose when liquid relief in the prior art.
Description
Technical field
The present invention relates to solid phase microextraction pre-treatment component and solid-phase micro-extracting devices.
Background technology
Quick-fried pearl, also referred to as capsule, fragrant pearl, 2.6 ~ 3.6mm of diameter, a kind of pearl racked in quick-fried pearl cigarette filter squeeze
It is a kind of new cigarette flavoring mode with the feeling to pop when broken.By the quick-fried pearl of sealing, fragrance is avoided directly to be connect with the external world
It touches, maintains the stabilization of fragrance matter, reduce external environment and the influence essence with caused by for inhaling taste is lost, in quick-fried pearl solution
Volatile flavor compounds are quick-fried pearl cigarette fragrance style supportive material bases, therefore especially to the detection of quick-fried pearl fragrance matter
The detection of volatile ingredient is extremely important.
Solid phase microextraction（Solid-phase micro-extraction, SPME）It is that one kind being directed to analysis of volatile components
Very effective method, give using the vitreous silica fiber for being coated with stationary phase adsorb, the test substance in enriched sample,
Analyte is concentrated while extraction, the fiber for being enriched determinand is then transferred directly to liquid phase or gas-chromatography
In, it is parsed by way of Thermal desorption or solution parsing, carries out sample analysis.
The utility model patent that Authorization Notice No. is CN206593939U, authorized announcement date is 2017.10.27 discloses one
Device of the kind suitable for solid phase microextraction in-site detecting, including extraction needle and ground glass stoppered bottle will extract when using the device
Needle is inserted into ground glass stoppered bottle carries out situ extracting to the sample in ground glass stoppered bottle, but for analyzing quick-fried pearl using SPME
There are some outstanding problems when volatile fragrant components：Solution, which needs to be transferred in ground glass stoppered bottle, after quick-fried pearl is broken is adsorbed
Extraction, this process not only results in the loss of volatile ingredient, and is easy to cause pollution and the sample loss of sample（Such as it is quick-fried
It is splashed in pearl shattering process in container inner wall and is difficult to shift）, bring some inconvenience to operation.
Invention content
The purpose of the present invention is to provide a kind of solid phase microextraction pre-treatment component, meeting when solving liquid relief in the prior art
The problem of causing volatile ingredient to lose；The present invention also aims to provide a kind of solid phase microextraction dress using the component
It sets.
To achieve the above object, the technical solution of solid phase microextraction pre-treatment component of the present invention is：
Solid phase microextraction pre-treatment component includes extraction flask and sample bottle, and the sample for will be placed in it is equipped in sample bottle
The extrusion structure for squeezing and squeezing out the object to be extracted in it, extraction flask are connected to sample bottle and enable the object to be extracted being extruded
Enough to enter in extraction flask from sample bottle, there is extraction flask the bottleneck passed through for extraction needle, the bottle mouth position to be equipped with for extracting
When needle is inserted into extraction flask with extraction needle sealing cooperation extraction flask sealing structure, the extrusion structure include extrusion head and
It is relatively fixed and is arranged and with sample bottle threaded engagement and when rotated with sample bottle in the direction of extrusion in the direction of extrusion with extrusion head
The upper spinning structure relatively moved.
The beneficial effects of the invention are as follows：So that it is squeezed sample in sample bottle come rotary squeezing head using spinning structure, makes
The object to be extracted overflowed in sample enters in extraction flask and the syringe needle by extracting needle adsorbs, and then carries out subsequent analysis experiment,
It avoids the object to be extracted in sample from contacting or evaporate into air with air, solves that when liquid relief in the prior art volatility can be caused
The problem of component damages.
Further, the extraction flask is wholely set with sample bottle, compacter using integral structure, and occupied space is more
It is small, more convenient operation.
Further, the extraction flask and sample bottle bottleneck towards opposite and shared bottom of bottle, the extraction flask and sample
The bottom of bottle of product bottle is equipped with connecting hole so that extraction flask be connected to sample bottle, simplifies structure, easy to process and manufacture.
Further, the connecting hole is equipped with multiple, and the aperture of each connecting hole is respectively less than the size of sample, avoids smaller
Sample without squeeze be directly entered impact analysis result in extraction flask.
Further, the extrusion structure includes cylindrical base, and the cylindrical base constitutes the extrusion head, described
Spinning structure setting simplifies the structure of sample bottle, reduces the difficulty of processing of sample bottle on the peripheral surface of cylindrical base.
Further, the spinning structure is the external screw thread being arranged on cylindrical base peripheral surface, on the sample bottle
Equipped with the internal thread with the external screw thread threaded engagement on cylindrical base peripheral surface, easy to process and manufacture.
Further, the internal thread sealing cooperation on the external screw thread and sample bottle on the cylindrical base peripheral surface, keeps away
Exempt from gap of the object to be extracted in sample between extrusion head and sample bottle to overflow.
Further, the extraction flask sealing structure is that the bottle mouth position in extraction flask is arranged for extracting the rubber being needled into
Sealing element, because rubber has certain elasticity, it is close can be in rubber with extraction needle for rubber seal after extraction is needled into
Part sealing cooperation in sealing, after extraction needle is extracted, rubber seal restores deformation and remains to play sealing extraction flask
Effect.
Further, the rubber seal is rubber gasket, reduces the stroke that extraction is needled into rubber seal, more
Add laborsaving.
Further, the removable bottle being fixed with for rubber gasket to be fitted in extraction flask of the bottle mouth position of the extraction flask
Head cover at mouthful, convenient for carrying out dismounting cleaning to extraction flask.
Further, the head cover is threadedly coupled with the bottle mouth position of extraction flask so that the removable bottle for being fixed on extraction flask of head cover
At mouthful, the head cover is equipped with the head cover installed for the needle portion of extraction flask and perforates, and is fixed by the way of screwing head cover
Head cover, convenient for manual operation.
Further, the head cover perforation is stepped hole, includes being installed for extracting the extraction needle that the needle portion of needle installs
Section and the bottleneck linkage section being connect with the whorl of bottleneck of extraction flask, are convenient for the installation and sealing of head cover by the way of threaded engagement
The press fitting of pad.
The technical solution of solid-phase micro-extracting device of the present invention is：
Solid-phase micro-extracting device includes extraction needle and solid phase microextraction pre-treatment component, the solid phase microextraction pre-treatment component packet
Extraction flask and sample bottle are included, the sample for will be placed in it is installed in sample bottle and squeezes and squeezes out the object to be extracted in it
Extrusion structure, extraction flask is connected to sample bottle and the object to be extracted being extruded enable to enter in extraction flask from sample bottle, extracts
Take bottle to have for the bottleneck that passes through of extraction needle, the bottle mouth position be equipped with for when extracting needle and being inserted into extraction flask with extraction needle
The extraction flask sealing structure of cooperation is sealed, the extrusion structure includes extrusion head and is relatively fixed in the direction of extrusion with extrusion head
The spinning structure for being arranged and being relatively moved in a pressing direction with sample bottle when rotated with sample bottle threaded engagement.
The beneficial effects of the invention are as follows：So that it is squeezed sample in sample bottle come rotary squeezing head using spinning structure, makes
The object to be extracted overflowed in sample enters in extraction flask and the syringe needle by extracting needle adsorbs, and then carries out subsequent analysis experiment,
It avoids the object to be extracted in sample from contacting or evaporate into air with air, solves that when liquid relief in the prior art volatility can be caused
The problem of component damages.
Further, the extraction flask is wholely set with sample bottle, compacter using integral structure, and occupied space is more
It is small, more convenient operation.
Further, the extraction flask and sample bottle bottleneck towards opposite and shared bottom of bottle, the extraction flask and sample
The bottom of bottle of product bottle is equipped with connecting hole so that extraction flask be connected to sample bottle, simplifies structure, easy to process and manufacture.
Further, the connecting hole is equipped with multiple, and the aperture of each connecting hole is respectively less than the size of sample, avoids smaller
Sample without squeeze be directly entered impact analysis result in extraction flask.
Further, the extrusion structure includes cylindrical base, and the cylindrical base constitutes the extrusion head, described
Spinning structure setting simplifies the structure of sample bottle, reduces the difficulty of processing of sample bottle on the peripheral surface of cylindrical base.
Further, the spinning structure is the external screw thread being arranged on cylindrical base peripheral surface, on the sample bottle
Equipped with the internal thread with the external screw thread threaded engagement on cylindrical base peripheral surface, easy to process and manufacture.
Further, the internal thread sealing cooperation on the external screw thread and sample bottle on the cylindrical base peripheral surface, keeps away
Exempt from gap of the object to be extracted in sample between extrusion head and sample bottle to overflow.
Further, the extraction flask sealing structure is that the bottle mouth position in extraction flask is arranged for extracting the rubber being needled into
Sealing element, because rubber has certain elasticity, it is close can be in rubber with extraction needle for rubber seal after extraction is needled into
Part sealing cooperation in sealing, after extraction needle is extracted, rubber seal restores deformation and remains to play sealing extraction flask
Effect.
Further, the rubber seal is rubber gasket, reduces the stroke that extraction is needled into rubber seal, more
Add laborsaving.
Further, the removable bottle being fixed with for rubber gasket to be fitted in extraction flask of the bottle mouth position of the extraction flask
Head cover at mouthful, convenient for carrying out dismounting cleaning to extraction flask.
Further, the head cover is threadedly coupled with the bottle mouth position of extraction flask so that the removable bottle for being fixed on extraction flask of head cover
At mouthful, the head cover is equipped with the head cover installed for the needle portion of extraction flask and perforates, and is fixed by the way of screwing head cover
Head cover, convenient for manual operation.
Further, the head cover perforation is stepped hole, includes being installed for extracting the extraction needle that the needle portion of needle installs
Section and the bottleneck linkage section being connect with the whorl of bottleneck of extraction flask, are convenient for the installation and sealing of head cover by the way of threaded engagement
The press fitting of pad.
Description of the drawings
Fig. 1 is the structural schematic diagram of the specific embodiment 1 of the solid-phase micro-extracting device of the present invention；
Fig. 2 is the structural schematic diagram of the partition board of the specific embodiment 1 of the solid-phase micro-extracting device of the present invention；
Fig. 3 is the structural schematic diagram of the specific embodiment 14 of the solid-phase micro-extracting device of the present invention；
Fig. 4 is the structural schematic diagram of the specific embodiment 15 of the solid-phase micro-extracting device of the present invention；
Fig. 5 is the structural schematic diagram of the specific embodiment 16 of the solid-phase micro-extracting device of the present invention.
Specific implementation mode
Embodiments of the present invention are described further below in conjunction with the accompanying drawings.
The specific embodiment 1 of the solid phase microextraction pretreating device of the present invention, as shown in Figure 1 to Figure 2, the present invention is with to quick-fried
Liquid in pearl is further described embodiments of the present invention for being extracted, wherein quick-fried pearl constitutes sample, quick-fried pearl
Interior liquid constitutes object to be extracted, but does not limit the purposes of the present invention, and the present invention also can be applicable to vegetable in other embodiments
In the extraction of the liquid such as dish, fruit.
In the present embodiment, solid-phase micro-extracting device includes extraction needle and solid phase microextraction pre-treatment component, solid phase microextraction
Pre-treatment component includes bottle 4, and bottle 4 is cylindrical in shape, and the shape of bottle 4 can also be according to practical need in other embodiments certainly
It is changed.Bottle 4 is an integral structure including upper and lower two parts, wherein it is extraction flask 5 to be placed in top, is placed in extraction flask
5 lower sections are sample bottle 7, and the partition board 6 for keeping apart extraction flask 5 and sample bottle 7, partition board are equipped between extraction flask 5 and sample bottle 7
6 constitute the bottom of bottle of extraction flasks 5 and sample bottle 7, the bottleneck of the bottleneck and sample bottle 7 that make extraction flask 5 towards opposite and shared bottom of bottle,
Partition board 6 is equipped with several connecting holes 601, so that extraction flask 5 is connected with sample bottle 7 by connecting hole 601.In view of quick-fried pearl
Minimum diameter, therefore the aperture of connecting hole 601 is arranged in 2mm hereinafter, keeping the minimum that the aperture of connecting hole 601 is less than quick-fried pearl straight
Diameter avoids quick-fried pearl from being passed through out of connecting hole 601, and the capsule crust of quick-fried pearl has also stayed in sample bottle 7, convenient for complete in operation
At later by the taking-up of the capsule crust of quick-fried pearl.
In the present embodiment, since the liquid component in quick-fried pearl is mostly volatile materials, in order to ensure the accurate of experimental result
Property and avoid the loss of liquid in quick-fried pearl, therefore, also removable at extraction flask bottleneck 401 to be fixed with head cover 2, head cover 2 is equipped with
The head cover perforation 3 that needle portion for extracting needle 1 passes through makes the body sections of extraction needle can be placed on head cover 2 convenient for extraction
The support for taking needle 1, for the ease of the fixation of head cover 2, the head cover perforation 3 in the present embodiment is stepped hole, including is used for and extraction
The major diameter section 302 coordinated at bottle bottleneck 401 and the path section 301 for being installed for extracting the needle portion of needle 1, wherein path section
301 are arranged in the top of major diameter section 302, and the madial wall of major diameter section 302 is equipped with internal thread, is equipped at extraction flask bottleneck 401 outer
Screw thread makes head cover 2 be threaded togather with bottle 4, in order to further ensure to extract by internal thread and externally threaded screw
The leakproofness of bottle 5 is taken, rubber gasket 11 is additionally provided between the planar annular and extraction flask bottleneck 401 in head cover perforation 3, passes through
Head cover 2 makes rubber gasket 11 is removable to be fixed on extraction flask bottle with the compressing rubber gasket 11 that screws at extraction flask bottleneck 401
In the opening's edge of mouth 401, and when extraction needle 1 wears out rubber gasket 11,11 flexible deformation of rubber gasket makes rubber seal
Pad 11 and the extraction sealing cooperation of needle 1, achieve the purpose that extraction flask 5 seals.Wherein, the major diameter section 302 of head cover perforation 3 constitutes screw thread
The path section 301 of the bottleneck linkage section being connected at extraction flask bottleneck 401, head cover perforation 3 constitutes the needle portion for extracting needle 1
The extraction needle installed installs section, and rubber gasket 11 constitutes the rubber for being arranged at extraction flask bottleneck 401 and being pierced into for extraction needle 1
Sealing element, rubber seal constitute the extraction flask sealing structure for sealing extraction flask 5, and certainly, head cover 2 can also pass through buckle
It is installed at extraction flask bottleneck 401 to make head cover 2 is removable to be fixed on bottle 4.Wherein, described in the present embodiment and extraction needle
1 is a kind of tubular type acicular texture, extracts and is provided with extraction syringe needle on needle 1, be used for sorption extraction liquid or gaseous sample, because of extraction
Therefore needle 1 does not do for the prior art and excessively repeats herein.
In the present embodiment, 7 one end directed downwardly of sample bottle be equipped with for quick-fried pearl enter sample bottle bottleneck 402, sample bottle 7 it is interior
There is internal thread, it includes cylindric matrix and setting to go back threaded engagement to have extrusion head, extrusion head on the internal thread of sample bottle 7 on wall
On extrusion head peripheral surface with the external screw thread of the internal thread segment threaded engagement of sample bottle 7, by the rotation of extrusion head 8 and to moving up
The quick-fried pearl that the volume of dynamic pressure contracting sample bottle 7 and extruding are placed in sample bottle 7 makes the liquid in quick-fried pearl overflow and by connecting hole 601
Into in extraction flask 5, and the gap in order to avoid the liquid of quick-fried pearl spilling between extrusion head 8 and the internal chamber wall of sample bottle 7
Outflow, therefore the external screw thread on extrusion head 8 coordinates with the internal thread sealing on sample bottle 7.Wherein, the external screw thread structure of extrusion head 8
It is arranged and is being squeezed when rotated with sample bottle 7 with 7 threaded engagement of sample bottle at is relatively fixed in the direction of extrusion with extrusion head 8
The external screw thread of the spinning structure relatively moved on pressure direction, extrusion head and extrusion head 8 is constituted for will be placed in sample bottle 7
Sample squeeze and by sample bottle 7 object to be extracted squeeze out extrusion structure.Certainly in other embodiments, spinning structure can
With including being arranged the helicla flute at sample bottle bottleneck 402, corresponding extrusion head be equipped in rotary squeezing head along spiral shell
Spin slot slides and upward guide pin, by rotary squeezing head and in the work of guide pin and helicla flute being slidably matched
Under, extrusion head is made to move up simultaneously pressing materials.
When using the solid-phase micro-extracting device, first passes through head cover perforation 3 to be placed on head cover 2 on extraction needle 1, make extraction
The needle portion of needle 1 is inserted into extraction flask 5, and then quick-fried pearl is placed into sample bottle 7, and extrusion head 8 is then screwed into sample
In product bottle 7, rotation extrusion head makes extrusion head 8 move up and quick-fried pearl is fitted on partition board 6, in squeezing for extrusion head 8 and partition board 6
Pressure makes the capsules break outside quick-fried pearl and the liquid in the capsule of quick-fried pearl is made to overflow, and is rotated further extrusion head 8, and the liquid of spilling is logical
The connecting hole 601 crossed on partition board 6 enters in extraction flask 5, completes solid phase microextraction in situ, and the needle portion of needle 1 to be extracted is inhaled
After attached a period of time, extraction needle 1 can be directly inserted into gas phase or liquid chromatogram instrument carry out analysis test with that.
Above-mentioned specific embodiment 1 is the optimal embodiment of the solid-phase micro-extracting device of the present invention, can in other embodiment
Corresponding structure is adjusted or be simplified as needed：
The specific embodiment 2 of the solid-phase micro-extracting device of the present invention simplifies the structure of solid-phase micro-extracting device in the present embodiment,
Solid-phase micro-extracting device includes extraction needle and solid phase microextraction pre-treatment component, and the solid phase microextraction pre-treatment component includes extraction
Bottle and sample bottle are taken, the sample for will be placed in it is installed in sample bottle and squeezes and is squeezed what the object to be extracted in it squeezed out
Laminated structure, extraction flask are connected to sample bottle and the object to be extracted being extruded are enable to enter in extraction flask from sample bottle, extraction flask
With the bottleneck passed through for extracting needle, the bottle mouth position is equipped with for being sealed with extraction needle when extracting needle and being inserted into extraction flask
The extraction flask sealing structure of cooperation, the extrusion structure include that extrusion head and being relatively fixed in the direction of extrusion with extrusion head is set
Set and with sample bottle threaded engagement and the spinning structure that is relatively moved in a pressing direction with sample bottle when rotated, lead to
Rotation extrusion head is crossed in sample bottle to squeeze sample, the object to be extracted overflowed in sample is made to enter in extraction flask and passes through extraction
The syringe needle of needle adsorbs, and then carries out subsequent analysis experiment, and the object to be extracted in sample is avoided to contact or evaporate into air with air
In, it avoids volatile ingredient being caused to lose when liquid relief.
The specific embodiment 3 of the solid-phase micro-extracting device of the present invention, the tool as the solid-phase micro-extracting device to the present invention
Body embodiment 2 advanced optimizes, and the extraction flask is wholely set with sample bottle, keeps the structure of extraction flask and sample bottle tighter
It gathers.Certainly in other embodiments, extraction flask and sample bottle may be split structure.
The specific embodiment 4 of the solid-phase micro-extracting device of the present invention, the tool as the solid-phase micro-extracting device to the present invention
Body embodiment 3 advanced optimizes, the bottleneck of the extraction flask and sample bottle towards opposite and shared bottom of bottle, the extraction flask and
The bottom of bottle of sample bottle is equipped with connecting hole so that extraction flask is connected to sample bottle.Certainly, in other embodiments, bottle can also
Two parallel-segments for U-tube, U-tube respectively constitute sample bottle and extraction flask, and the bend loss of U-tube constitutes connection sample bottle and extraction
Take the interface channel of bottle.
The specific embodiment 5 of the solid-phase micro-extracting device of the present invention, the tool as the solid-phase micro-extracting device to the present invention
Body embodiment 4 advanced optimizes, the connecting hole be equipped with it is multiple, the aperture of each connecting hole is respectively less than the size of sample, by
Sample selection in this present embodiment is quick-fried pearl, and the minimum diameter of quick-fried pearl in the market is about 2.6mm, therefore uses and be less than
The connecting hole in the apertures 2mm avoids quick-fried pearl from being directly pierced by from connecting hole.Certainly, in other embodiments, not according to sample
Together, the aperture of connecting hole is arbitrary.
The specific embodiment 6 of the solid-phase micro-extracting device of the present invention, the tool as the solid-phase micro-extracting device to the present invention
Any of body embodiment 2 to 5 advanced optimizes, and the extrusion structure includes cylindrical base, the cylindrical base structure
At the extrusion head, the spinning structure setting is on the peripheral surface of cylindrical base.Certainly in other embodiments, spinning knot
Structure may also be arranged on sample bottle bottle mouth position.
The specific embodiment 7 of the solid-phase micro-extracting device of the present invention, the tool as the solid-phase micro-extracting device to the present invention
Body embodiment 6 advanced optimizes, and the spinning structure is the external screw thread being arranged on cylindrical base peripheral surface, the sample
Bottle is equipped with the internal thread with the external screw thread threaded engagement on cylindrical base peripheral surface.Certainly, in other embodiments, spinning
Structure can be the helicla flute being arranged at sample bottle bottleneck 402, and corresponding extrusion head is equipped in rotary squeezing head
Along helicla flute sliding and upward guide pin, pass through being slidably matched in rotary squeezing head and in guide pin and helicla flute
Under the action of, so that extrusion head is moved up simultaneously pressing materials.
The specific embodiment 8 of the solid-phase micro-extracting device of the present invention, the tool as the solid-phase micro-extracting device to the present invention
Body embodiment 7 advanced optimizes, and the internal thread sealing on the external screw thread and sample bottle on the cylindrical base peripheral surface is matched
It closes.
The specific embodiment 9 of the solid-phase micro-extracting device of the present invention, the tool as the solid-phase micro-extracting device to the present invention
Any of body embodiment 2 to 5 advanced optimizes, the extraction flask sealing structure be arranged the bottle mouth position in extraction flask for
Extract the rubber seal being needled into.Certainly, extraction flask sealing structure can also be on rubber seal in other embodiments
The seal and opening that a diameter is less than extraction needle and the mating part diameter of extraction flask sealing structure is opened up, is passed through in extraction needle close
When seal opening, rubber seal is extruded and flexible deformation occurs to realize the sealing of extraction flask.
The specific embodiment 10 of the solid-phase micro-extracting device of the present invention, the tool as the solid-phase micro-extracting device to the present invention
Body implementation 9 advanced optimizes, and the rubber seal is rubber gasket.Certainly, in other embodiments, rubber seal
Or plug is mounted in the extraction flask sealing-plug of extraction flask bottleneck.
The specific embodiment 11 of the solid-phase micro-extracting device of the present invention, the tool as the solid-phase micro-extracting device to the present invention
Body embodiment 10 advanced optimizes, and the bottle mouth position of the extraction flask is removable to be fixed with for rubber gasket to be fitted in extraction
The head cover of the bottle mouth position of bottle.Certainly, in other embodiments, rubber gasket can also be bonded in the opening's edge of extraction flask bottleneck
On.
The specific embodiment 12 of the solid-phase micro-extracting device of the present invention, the tool as the solid-phase micro-extracting device to the present invention
Body embodiment 11 advanced optimizes, and the head cover is threadedly coupled with the bottle mouth position of extraction flask so that head cover is removable to be fixed on extraction
The bottle mouth position of bottle, the head cover are equipped with the head cover installed for the needle portion of extraction flask and perforate.Certainly, in other embodiment
In, can also be arranged in the bottle mouth position of extraction flask and buckle, head cover be equipped with the notch or extension that are clasped, will by buckling
Head cover is connected to the bottle mouth position of extraction flask.
The specific embodiment 13 of the solid-phase micro-extracting device of the present invention, the tool as the solid phase microextraction sole duty to the present invention
Body embodiment 12 advanced optimizes, and the head cover perforation is stepped hole, includes the extraction installed for extracting the needle portion of needle
Needle installs section and the bottleneck linkage section with the bottleneck releasable connection of extraction flask.Certainly, in other embodiments, head cover perforation is logical
Hole, head cover peripheral surface are equipped with the external screw thread being threadedly coupled with extraction flask bottle mouth position.
The specific embodiment 14 of the solid-phase micro-extracting device of the present invention, the specific reality with the solid-phase micro-extracting device of the present invention
Apply differing only in for example 1：As shown in figure 3, sample bottle 27 and extraction flask 25 are separate structure, the bottom plate of sample bottle 27 and extraction
It is connected to by interface channel 26 between bottle 25.
The specific embodiment 15 of the solid-phase micro-extracting device of the present invention, the specific reality with the solid-phase micro-extracting device of the present invention
Apply differing only in for example 1：As shown in figure 4, the bottom wall of sample bottle 37 is fixed on the side wall of extraction flask 35, the side of extraction flask 35
The extraction flask perforation 36 for being connected to extraction flask 35 with sample bottle 37 is additionally provided on wall.
The specific embodiment 16 of the solid-phase micro-extracting device of the present invention, the specific reality with the solid-phase micro-extracting device of the present invention
Apply differing only in for example 1：As shown in figure 5, the peripheral surface of the bottle mouth position of sample bottle 47 is equipped with the spiral of upward spiral setting
Slot 49, the inner peripheral surface of corresponding extrusion head 48 are equipped with the guide pin being slidably matched with helicla flute 49 in rotary squeezing head 48
410, in rotary squeezing head 48, guide pin 410 slides in helicla flute 49 so that extrusion head 48 moves up to which realization is squeezed
The purpose of pressure-like product.
The specific embodiment 17 of the solid-phase micro-extracting device of the present invention, the specific reality with the solid-phase micro-extracting device of the present invention
Apply differing only in for example 1：The cavity wall of sample bottle is equipped with the material inlet for entering sample bottle for quick-fried pearl.
The specific embodiment 18 of the solid-phase micro-extracting device of the present invention, the specific reality with the solid-phase micro-extracting device of the present invention
Apply differing only in for example 1：Extrusion head include spiro rod section and be placed in spiro rod section upper end and with screw rod end it is hinged for squeeze it is quick-fried
The platen section of pearl, sample bottle opening are equipped with end cap, and end cap is equipped with the end cap passed through for the screw rod end of extrusion head and perforates, end cap
The hole wall of perforation is equipped with the internal thread with spiro rod section screw-thread fit.
The specific embodiment 19 of the solid-phase micro-extracting device of the present invention, the specific reality with the solid-phase micro-extracting device of the present invention
Apply differing only in for example 1：On the lower face of partition board and/or extrusion head compressive plane is equipped with the dentate body of protrusion, is convenient for quick-fried pearl
Crust is crushed.
The specific embodiment of the solid phase microextraction pre-treatment component of the present invention, the tool with the solid-phase micro-extracting device of the present invention
Solid phase microextraction pre-treatment component described in any one of body embodiment 1-19 is identical, repeats no more.
Claims (24)
1. solid phase microextraction pre-treatment component, it is characterised in that：Including extraction flask and sample bottle, it is equipped in sample bottle for inciting somebody to action
The sample placed in it squeezes and by the extrusion structure of the object to be extracted extrusion in it, and extraction flask is connected to sample bottle and makes to be squeezed
The object to be extracted gone out can enter from sample bottle in extraction flask, and extraction flask has the bottleneck passed through for extraction needle, the bottle mouth position
Equipped with for the extraction flask sealing structure when extracting needle and being inserted into extraction flask with extraction needle sealing cooperation, the extrusion structure
Including extrusion head and with extrusion head the direction of extrusion be relatively fixed setting and with sample bottle threaded engagement and when rotated with sample
The spinning structure that product bottle relatively moves in a pressing direction.
2. solid phase microextraction pre-treatment component according to claim 1, it is characterised in that：The extraction flask and sample bottle one
Body is arranged.
3. solid phase microextraction pre-treatment component according to claim 2, it is characterised in that：The extraction flask and sample bottle
Bottleneck towards opposite and shared bottom of bottle, the bottom of bottle of the extraction flask and sample bottle is equipped with connecting hole so that extraction flask and sample
Bottle connection.
4. solid phase microextraction pre-treatment component according to claim 3, it is characterised in that：The connecting hole be equipped with it is multiple,
The aperture of each connecting hole is respectively less than the size of sample.
5. the solid phase microextraction pre-treatment component according to any one of claim 1-4, it is characterised in that：The extruding knot
Structure includes cylindrical base, and the cylindrical base constitutes the extrusion head, and the spinning structure setting is in cylindrical base
On peripheral surface.
6. solid phase microextraction pre-treatment component according to claim 5, it is characterised in that：The spinning structure is that setting exists
External screw thread on cylindrical base peripheral surface, the sample bottle is equipped with matches with the external screw thread spiral on cylindrical base peripheral surface
The internal thread of conjunction.
7. solid phase microextraction pre-treatment component according to claim 6, it is characterised in that：The cylindrical base peripheral surface
On external screw thread and sample bottle on internal thread sealing cooperation.
8. the solid phase microextraction pre-treatment component according to any one of claim 1-4, it is characterised in that：The extraction flask
Sealing structure is that the bottle mouth position in extraction flask is arranged for extracting the rubber seal being needled into.
9. solid phase microextraction pre-treatment component according to claim 8, it is characterised in that：The rubber seal is rubber
Gasket.
10. solid phase microextraction pre-treatment component according to claim 9, it is characterised in that：The bottle mouth position of the extraction flask
The removable head cover for being fixed with the bottle mouth position for rubber gasket to be fitted in extraction flask.
11. solid phase microextraction pre-treatment component according to claim 10, it is characterised in that：The head cover and extraction flask
Bottle mouth position is threadedly coupled so that the removable bottle mouth position for being fixed on extraction flask of head cover, the head cover are equipped with the needle section for extraction flask
Divide the head cover perforation installed.
12. solid phase microextraction pre-treatment component according to claim 11, it is characterised in that：The head cover perforation is ladder
Hole includes installing section and the bottleneck being connect with the whorl of bottleneck of extraction flask connection for extracting the extraction needle that the needle portion of needle installs
Section.
13. solid-phase micro-extracting device, including extraction needle and solid phase microextraction pre-treatment component, it is characterised in that：The solid phase is micro-
Extract pre-treatment component include extraction flask and sample bottle, be equipped in sample bottle for will be placed it in sample extruding and by its
The extrusion structure that interior object to be extracted squeezes out, extraction flask are connected to sample bottle and enable the object to be extracted being extruded from sample bottle
Into in extraction flask, there is extraction flask the bottleneck passed through for extraction needle, the bottle mouth position to be equipped with for being inserted into extraction in extraction needle
Include extrusion head with the extraction flask sealing structure of extraction needle sealing cooperation, the extrusion structure when taking in bottle and exist with extrusion head
The direction of extrusion be relatively fixed setting and with sample bottle threaded engagement and occurs in a pressing direction with sample bottle when rotated relatively
Mobile spinning structure.
14. solid-phase micro-extracting device according to claim 13, it is characterised in that：The extraction flask is integrally set with sample bottle
It sets.
15. solid-phase micro-extracting device according to claim 14, it is characterised in that：The extraction flask and sample bottle bottle
Mouthful towards opposite and shared bottom of bottle, the bottom of bottle of the extraction flask and sample bottle is equipped with connecting hole so that extraction flask and sample bottle connect
It is logical.
16. solid-phase micro-extracting device according to claim 15, it is characterised in that：The connecting hole be equipped with it is multiple, each
The aperture of connecting hole is respectively less than the size of sample.
17. according to the solid-phase micro-extracting device described in any one of claim 13-16, it is characterised in that：The extrusion structure
Including cylindrical base, the cylindrical base constitutes the extrusion head, and the spinning structure setting is in the outer of cylindrical base
On circumferential surface.
18. solid-phase micro-extracting device according to claim 17, it is characterised in that：The spinning structure is to be arranged in cylinder
External screw thread on shape matrix peripheral surface, the sample bottle are equipped with and the external screw thread threaded engagement on cylindrical base peripheral surface
Internal thread.
19. solid-phase micro-extracting device according to claim 18, it is characterised in that：On the cylindrical base peripheral surface
External screw thread coordinates with the internal thread sealing on sample bottle.
20. according to the solid-phase micro-extracting device described in any one of claim 13-16, it is characterised in that：The extraction flask is close
Seal structure is that the bottle mouth position in extraction flask is arranged for extracting the rubber seal being needled into.
21. solid-phase micro-extracting device according to claim 20, it is characterised in that：The rubber seal is rubber seal
Pad.
22. solid-phase micro-extracting device according to claim 21, it is characterised in that：The bottle mouth position of the extraction flask is removable solid
Surely it is useful for for rubber gasket being fitted in the head cover of the bottle mouth position of extraction flask.
23. solid-phase micro-extracting device according to claim 22, it is characterised in that：The bottle mouth position of the head cover and extraction flask
It is threadedly coupled so that the removable bottle mouth position for being fixed on extraction flask of head cover, the head cover are installed equipped with the needle portion for extraction flask
Head cover perforation.
24. solid-phase micro-extracting device according to claim 23, it is characterised in that：The head cover perforation is stepped hole, packet
Include the bottleneck linkage section for installing section for extracting the extraction needle that the needle portion of needle installs and being connect with the whorl of bottleneck of extraction flask.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201810284374.9A CN108310804B (en) | 2018-04-02 | 2018-04-02 | Solid-phase microextraction pretreatment assembly and solid-phase microextraction device |
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| CN201810284374.9A CN108310804B (en) | 2018-04-02 | 2018-04-02 | Solid-phase microextraction pretreatment assembly and solid-phase microextraction device |
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| CN108310804B CN108310804B (en) | 2023-08-01 |
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Cited By (1)
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| CN112763633A (en) * | 2021-01-19 | 2021-05-07 | 云南中烟工业有限责任公司 | Device and method for determining heated migration components of filter stick additive by dynamic headspace method |
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| CN108310804B (en) | 2023-08-01 |
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