CN108303401A - A kind of fluorescence nano composite material and its application in metal ion detection - Google Patents
A kind of fluorescence nano composite material and its application in metal ion detection Download PDFInfo
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- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
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Abstract
The invention belongs to technical field of nanometer material preparation, and in particular to the patent application of a kind of fluorescence nano composite material and its application in metal ion detection.The material by prepare Au NCs@THPC/GSH/MUA solution, synthesis Au NCs@GSH, the compound gold nanoclusters of synthesis and etc. be prepared, the material can, for the Pb in specific identification sample2+And/or Cu2+.Fluorescence nano composite material provided herein, technology of preparing is more mature, easily operated.Preliminary Applications show prepared fluorescence nano composite material, can specificity while detection sample in Pb2+And Cu2+.And detection method, simple and effective, high sensitivity, preferable application effect is shown, thus there is important application value for the identification of metal ion sample.
Description
Technical field
The invention belongs to technical field of nanometer material preparation, and in particular to a kind of fluorescence nano composite material and its in metal
The patent application of application in ion detection.
Background technology
Using lead as some heavy metal elements of representative, due to very strong bio-toxicity, for a huge sum of money in environment
Belong to pollution, Accumulation of heavy metals problem needs especially to pay attention to.In the prior art, for content of beary metal detection technique in water have compared with
Multi-method, wherein fluorescence nano clustered materials have having great advantage in terms of detection of heavy metal ion, therefore have obtained very fast development.
In the prior art, it when being identified to metal ion using nano-cluster and then carrying out assay, typically utilizes single
Nano-cluster carries out specific recognition to a certain metal ion species, to realize the detection to Gold Samples category ion.But it is this
Due to can only be detected every time to a metal ion species, thus when facing various metals detection demand, just face multiple weight
The drawbacks of operating again.Therefore, exploitation is a kind of efficient, cheap, easily and efficiently, can simultaneously be identified to various metals ion
Method has highly important application value.
Invention content
The main purpose of the present invention is to provide a kind of fluorescence nano composite material, which can be to various metals ion simultaneously
Detection is identified, there is in terms of metal ion detection preferable application value in the sample.
Details are as follows for technical scheme of the present invention.
A kind of fluorescence nano composite material, is made by the steps：
（1）Au NCs@THPC/GSH/MUA solution is prepared, the specific steps are：
（1.1）The THPC for being 80% by the NaOH solution of a concentration of 1 M of 125 μ L and 3 μ L mass fractions（Tetra methylol chlorination
Phosphorus）Solution is added in the aqueous solution of 10 mL, and the HAuCl that 5.52 μ L mass fractions are 41.8% is rapidly added after stirring evenly4
（Tetra chlorauric acid）Solution obtains Au NCs@THPC solution, and solution colour becomes dark-brown by faint yellow at this time；
（1.2）The GSH of a concentration of 100 mM of 58.72 μ L is added（Glutathione）Solution is aged 12 h under the conditions of 4 DEG C, makes
GSH displacement competition package Au NCs@THPC form Au NCs@THPC/GSH；
（1.3）Take step（1.2）The phosphate that the pH of a concentration of 0.1 M of 800 μ L is 9.0 is added in 4 mL solution after middle ageing
The MUA of buffer solution and a concentration of 0.1 M of 200 μ L（11- Mercaptoundecanoic acids）Ethanol solution, stir 6 h, at this time solution
Become faint yellow from dark-brown, obtains Au NCs@THPC/GSH/MUA solution, this solution is under the irradiation of ultraviolet lamp (365 nm)
Show green light；
The Au NCs@THPC/GSH/MUA can be referred to as NCs1；
（2）The synthesis of Au NCs@GSH, is as follows：
The HAuCl that 8.12 μ L mass fractions are 41.8% is added into the GSH aqueous solutions of a concentration of 50 μM of 4.50 mL4Solution；
Fully reaction after stirring evenly（It is to react 24 h in the shaking table that 70 DEG C of rotating speeds are 300 rpm to be specifically for example put into temperature）；
The nano-cluster shows feux rouges under the irradiation of ultraviolet lamp (365 nm)；
The Au NCs@GSH can be referred to as NCs2；
（3）The synthesis of compound gold nanoclusters,
By step（1）In prepared NCs1（Au NCs@THPC/GSH/MUA are nanometer crystal druse form）And step（2）In it is made
Standby NCs2（Au NCs@GSH）After being sufficiently mixed（It specifically can be by NCs1：NCs2=1:2 volume ratio is mixed）, in room temperature（18
~ 25 DEG C or so）Lower completion hybrid experiment can prepare compound gold nanoclusters solution；
The nano-cluster sends out green-yellow light under the irradiation of ultraviolet lamp (365 nm)；
Prepared compound gold nanoclusters can be referred to as NCs3.
Application of the prepared fluorescence nano composite material in sample metal ion detection, in specific identification sample
Pb2+And/or Cu2+；
It is for Pb2+Lowest detection is limited to 0.60 nM, for Cu2+Lowest detection be limited to 0.42 nM.
Using the fluorescence nano composite material to the detection method of Gold Samples category ion, the metal ion is Pb2+
And/or Cu2+, include the following steps：
（1）First the lead ion and copper ion of fluorescence nano composite material solution and normal concentration are uniformly mixed, measure it 512
nm（Excitation wavelength 381）With 612 nm（Excitation wavelength 461）Fluorescence signal, draw relative intensity of fluorescence and ion concentration mark
Directrix curve；(612 nm correspond to Cu2+, 512 nm correspond to Pb2+)
（2）Unknown sample and fluorescence nano composite material are mixed again, measure its fluorescence intensity；
（3）Bring its relative intensity of fluorescence into standard curve, you can obtain Pb in unknown sample2+And/or Cu2+Specific concentration
Value.
In general, fluorescence nano composite material provided herein, technology of preparing is more mature, easily operated.
Preliminary Applications show prepared fluorescence nano composite material, can specificity while detection sample in Pb2+And Cu2+.And
And detection method, simple and effective, high sensitivity show preferable application effect, thus for the knowledge of metal ion sample
Application value that Ju You be unimportant.
Description of the drawings
Fig. 1 is the fluorescence spectra of Au NCs@THPC/GSH/MUA (figure A) and Au NCs@GSH (figure B), maximum excitation
Wavelength is 381 nm and 417 nm respectively, and maximum emission wavelength is respectively 512 nm and 612 nm；
Fig. 2 is the fluorescence spectrum of NCs3；Wherein lines indicate emission spectrum of the NCs3 under 381 nm and 417 nm excitations respectively
Figure；
Fig. 3 be the NCs1 solution that various concentration of metal ions are 10 μM I/I0 figure (I0- be added metal ion before fluorescence it is strong
The fluorescence intensity after metal ion is added in degree, I-)；Picture above it is the gold nanoclusters of above-mentioned corresponding different metal ions
Fluorescence photo of the solution under ultraviolet lamp (nm of λ=365) irradiation (is from left to right followed successively by：Blank、K+、Mg2+、Al3+、Co2 +、Cd2+、Ni2+、Cu2+、Fe3+、Cr3+、Zn2+、Ca2+、Pb2+、Mn2+、Na+、Hg2+)
Fig. 4 is that (metal ion includes for the I/I0 figures of the NCs2 solution that various concentration of metal ions are 14 μM：K+、Mg2+、Al3+、
Co2+、Cd2+、Ni2+、Cu2+、Fe3+、Cr3+、Zn2+、Ca2+、Pb2+、Mn2+、Na+、Hg2+)；Draw above piece is its corresponding difference
Fluorescence photo of the gold nanoclusters solution of metal ion under ultraviolet lamp (nm of λ=365) irradiation；
Fig. 5 is the Pb of various concentration2+With the relational graph of NCs3 solution fluorescence quenching rates；It is Pb to be inserted into figure2+Concentration 60 nM ~
7.0×103 Response curve within the scope of nM；
Fig. 6 is the Cu of various concentration2+With the relational graph of NCs3 solution fluorescence quenching rates；It is Cu to be inserted into figure2+Concentration 60 nM ~
7.0×103Response curve within the scope of nM.
Specific implementation mode
With reference to embodiment to itself being further explained explanation, before introducing specific embodiment, with regard to following implementations
Part experiment reagent and briefly introducing situations such as experimental facilities is described as follows in example.
Experiment reagent：
Mercaptoundecanoic acid (MUA), tetramethylol chloride (THPC), sodium hydroxid (NaOH), gold chloride (HAuCl4), paddy Guang
Sweet peptide (GSH) etc. is purchased from Sigma Aldriches；
Cu2+、Pb2+Equal metal ion solutions are by metal nitrates such as copper nitrate, plumbi nitras（Associated metal salt is purchased from traditional Chinese medicines public affairs
Department）It is formulated；
Experimental facilities：
LS-55 sepectrophotofluorometers, (excitation and transmite slit width are set as 5.0 for platinum Ai Ermo Instrument Ltd.
Nm) product.
Embodiment 1
The fluorescence nano composite material that the present embodiment is provided, is made by the steps.
（1）Au NCs@THPC/GSH/MUA solution is prepared, the specific steps are：
（1.1）The THPC for being 80% by the NaOH solution of a concentration of 1 M of 125 μ L and 3 μ L mass fractions（Tetra methylol chlorination
Phosphorus）Solution is added in the aqueous solution of 10 mL, and the HAuCl that 5.52 μ L mass fractions are 41.8% is rapidly added after stirring evenly4
（Tetra chlorauric acid）Solution obtains Au NCs@THPC solution, and solution colour becomes dark-brown by faint yellow at this time；
（1.2）The GSH of a concentration of 100 mM of 58.72 μ L is added（Glutathione）Solution makes GSH displacement competition packages Au
NCs@THPC form Au NCs@THPC/GSH；
It is aged 12 h under the conditions of 4 DEG C；
（1.3）Take step（1.2）The phosphate that the pH of a concentration of 0.1 M of 800 μ L is 9.0 is added in 4 mL solution after middle ageing
The MUA of buffer solution and a concentration of 0.1 M of 200 μ L（11- Mercaptoundecanoic acids）Ethanol solution, stir 6 h, at this time solution
Become faint yellow from dark-brown, obtains Au NCs@THPC/GSH/MUA solution, this solution is under the irradiation of ultraviolet lamp (365 nm)
Show green light；
For ease of description, the Au NCs@THPC/GSH/MUA can be referred to as NCs1；
（2）The synthesis of Au NCs@GSH, is as follows：
The HAuCl that 8.12 μ L mass fractions are 41.8% is added into the GSH aqueous solutions of a concentration of 50 μM of 4.50 mL4Solution；
Fully reaction after stirring evenly（It is to react 24 h in the shaking table that 70 DEG C of rotating speeds are 300 rpm to be specifically for example put into temperature）；
The nano-cluster shows feux rouges under the irradiation of ultraviolet lamp (365 nm)；
For ease of description, the Au NCs@GSH can be referred to as NCs2；
（3）The synthesis of compound gold nanoclusters,
By step（1）In prepared NCs1（Au NCs@THPC/GSH/MUA are nanometer crystal druse form）And step（2）In it is made
Standby NCs2（Au NCs@GSH）After being sufficiently mixed（It specifically can be by NCs1：NCs2=1:2 volume ratio is mixed）, at room temperature
Compound gold nanoclusters solution can be prepared by completing hybrid experiment；
The nano-cluster sends out green-yellow light under the irradiation of ultraviolet lamp (365 nm)；
Prepared compound gold nanoclusters can be referred to as NCs3.
Fluoroscopic examination is carried out respectively to NCs1, NCs2, NCs3, fluorescence spectrum difference is as shown in Figure 1 and Figure 2.
Embodiment 2
To Au NCs@THPC/GSH/MUA prepared in 1 reaction process of embodiment（NCs1）、Au NCs@GSH（NCs2）, it is multiple
Alloy nanocluster（NCs3）Specific assay has been carried out to the selectivity of different metal ions.Related experiment is briefly discussed below.
（One）Au NCs@THPC/GSH/MUA (NCs1) test the selectivity of metal ion
After the original solution of Au NCs@THPC/GSH/MUA (NCs1) is diluted 10 times with redistilled water（Stoste, that is, embodiment 1
The step of（1）In whole solution）, you can for being selectively measured to metal ion.Concrete operations are as follows：
Au NCs THPC/GSH/MUA (NCs1) solution after dilution is taken first, configures the standard of 200 μM of each metal ion species
Then gold nanoclusters solution is measured it with sepectrophotofluorometer.
Into the solution of gold nanoclusters NCs1（200 μL）The standard solution 10 of the different metal ions of comparable sodium is added
μ L investigate its influence to gold nanoclusters NCs1 fluorescence intensities（Fluorescence associated testing result is as shown in Figure 3）.
When there are micro Pb in gold nanoclusters NCs1 solution systems2+When, which just will appear stronger fluorescent quenching
Phenomenon (green fluorescence disappearance), and other metal ions influence smaller (there are green fluorescences) to the fluorescence of this system, wherein K+、
Mg2+、Al3+、Cu2+、Fe3+、Zn2+、Ca2+、Mn2+、Na+On the fluorescence intensity of the gold nanoclusters almost without influence, Jenner is illustrated
Rice cluster NCs1 is to Pb2+There is stronger selectivity.
（Two）Au NCs@GSH (NCs2) test the selectivity of metal ion
By Au NCs@GSH (NCs2) original solutions with redistilled water dilute 5 times, after according to it is above-mentioned "（One）Au NCs@THPC/
Method is measured metal ion in selectivity experiments of the GSH/MUA (NCs1) to metal ion ".
Different metal ions are added such as in NCs2 gold nanoclusters solution：K+、Mg2+、Al3+、Co2+、Cd2+、Ni2+、Cu2+、
Fe3+、Cr3+、Zn2+、Ca2+、Pb2+、Hg2+Deng to investigate it to the influence of the fluorescence intensity of gold nanoclusters NCs2（Fluorescence associated detects
The results are shown in Figure 4）.
As addition Cu2+Its red fluorescence disappears at a concentration of 14 μM of solution, illustrates Cu2+To the glimmering of gold nanoclusters NCs2
Light has quenching effect.And K+、Al3+、Co2+、Zn2+、Ca2+、Mn2+、Na+To the I/I0 of NCs2 solution in 90% or more, Mg2+、Fe3+、
Hg2+To the I/I0 of NCs2 solution between 78%-85%, and Cd2+、Ni2+、Cr3+、Pb2+To the I/I0 of NCs2 solution in 100%-
Between 110%, show that other metal ions are minimum to NCs2 solution fluorescence intensity effects.
（Three）Compound gold nanoclusters（NCs3）Selectivity experiment to metal ion
Assay method with it is above-mentioned "（One）Side in selectivity experiments of the Au NCs@THPC/GSH/MUA (NCs1) to metal ion "
Method.
By compound gold nanoclusters solution NCs3（The original solution redistilled water of Au NCs@THPC/GSH/MUA (NCs1)
After 10 times of dilution, 5 times of dilution Au NCs@GSH (NCs2) original solutions are mixed）Series of identical concentration is added（0~30 μM）Cu2+
And Pb2+Mixed solution（Fluorescence associated testing result is as shown in Figure 5, Figure 6）.
Under the excitation of the nm of Ex=381, fluorescence intensities of the NCs3 at 512 nm is with Cu2+The increase of concentration and subtract
It is small；Fluorescence intensity of the launch wavelength at 612 nm is with Pb2+The increase of concentration and reduce.The phenomenon shows that the composition metal is received
Rice cluster can identify Pb simultaneously2+And Cu2+Two kinds of substances
Pb2+Concentration is in 60 nM-7.00 × 103 Within the scope of nM, the Pb at the nm of launch wavelength Em=5122+Concentration is molten with NCs3
It is the E-05X+0.5972 of Y=4, phase that the quenching rate of the fluorescence intensity of liquid, which has good linear relationship, working curve equation,
Relationship number is R2=0.9727, and lowest detection is limited to 0.60 nM.
Under the excitation of 417 nm wavelength, fluorescence of the NCs3 solution at the nm of wavelength Em=612 is with Cu2+Concentration
Increase and weakens.At good linear relationship within the scope of the nM of 60 nM-7.00 × 103, meet the E- of Y=7 05X+0.4116
Working curve equation, related coefficient is R2=0.9772, and lowest detection is limited to 0.42 nM,
（Four）Detection to actual water sample
By water sample（Originally water sample）By filtering, the processing such as heat, boil, cool down, refilter, then respectively in 381 nm and
Pb is carried out to it under the exciting light of 417 nm2+And Cu2+It detects simultaneously, while and recovery testu is carried out to it.
As a result Tables 1 and 2, Cu are seen below2+And Pb2+The rate of recovery distinguish 98.69-115.65% and 94.08-105.86%,
It can be seen that its rate of recovery meets the requirements, to demonstrate the dependable with function of the method.
1 compound gold nanoclusters of table are to Cu2+Measurement
2 compound gold nanoclusters of table are to Pb2+Detection
。
Claims (5)
1. a kind of fluorescence nano composite material, which is characterized in that be made by the steps：
（1）Au NCs@THPC/GSH/MUA solution is prepared, the specific steps are：
（1-1）The THPC solution that the NaOH solution of a concentration of 1 M of 125 μ L and 3 μ L mass fractions are 80% is added to 10 mL
Aqueous solution in, be stirring evenly and then adding into 5.52 μ L mass fractions be 41.8% HAuCl4It is molten to obtain Au NCs@THPC for solution
Liquid；
（1-2）The GSH solution of a concentration of 100 mM of 58.72 μ L is added, is aged to form Au NCs@THPC/GSH；
（1-3）Take step（1-2）The phosphate that the pH of a concentration of 0.1 M of 800 μ L is 9.0 is added in 4 mL solution after middle ageing
The ethanol solution of the MUA of buffer solution and a concentration of 0.1 M of 200 μ L, are stirred to react, and it is molten to obtain Au NCs@THPC/GSH/MUA
Liquid；
The Au NCs@THPC/GSH/MUA are referred to as NCs1；
（2）The synthesis of Au NCs@GSH, is as follows：
The HAuCl that 8.12 μ L mass fractions are 41.8% is added into the GSH aqueous solutions of a concentration of 50 μM of 4.50 mL4Solution；It stirs
Fully reaction after mixing uniformly；
The Au NCs@GSH are referred to as NCs2；
（3）The synthesis of compound gold nanoclusters,
By step（1）In prepared NCs1 and step（2）In after prepared NCs2 is sufficiently mixed, complete hybridization, can get compound
Gold nanoclusters, referred to as NCs3, as fluorescence nano composite material.
2. fluorescence nano composite material as described in claim 1, which is characterized in that step（2）In, it is shaken in 70 DEG C, 300 rpm
24 h are reacted in bed, to ensure that reaction is abundant.
3. fluorescence nano composite material as described in claim 1, which is characterized in that step（3）In, by NCs1：NCs2=1:2
Volume ratio is mixed.
4. application of the fluorescence nano composite material described in claim 1 in sample metal ion detection, which is characterized in that be used for
Pb in specific identification sample2+And/or Cu2+。
5. using fluorescence nano composite material described in claim 1 to the detection method of Gold Samples category ion, which is characterized in that
The metal ion is Pb2+And/or Cu2+, include the following steps：
（1）It is first that fluorescence nano composite material solution, the lead ion of normal concentration and Ar ion mixing is uniform, it is measured in 512 nm
With the fluorescence signal of 612 nm, the standard curve of relative intensity of fluorescence and ion concentration is drawn；
（2）Unknown sample and fluorescence nano composite material are mixed again, measure its fluorescence intensity；
（3）Bring its relative intensity of fluorescence into standard curve, you can obtain Pb in unknown sample2+And/or Cu2+Specific concentration
Value.
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109520984A (en) * | 2018-12-06 | 2019-03-26 | 南通中国科学院海洋研究所海洋科学与技术研究发展中心 | The rapid detection method of sulfate reducing bacteria in a kind of briny environment |
| CN111504961A (en) * | 2020-03-31 | 2020-08-07 | 南昌大学 | Fluorescent sensor based on glutathione gold nanoclusters and application thereof |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103884701A (en) * | 2014-04-10 | 2014-06-25 | 中国烟草总公司郑州烟草研究院 | Mercury ion detection method |
| CN105352925A (en) * | 2015-10-26 | 2016-02-24 | 中国烟草总公司郑州烟草研究院 | Copper ions detection method based on nano-cluster |
| CN105548131A (en) * | 2016-03-03 | 2016-05-04 | 中国烟草总公司郑州烟草研究院 | Preparation method of array fluorescent nano-cluster sensor and application of array fluorescent nano-cluster sensor to metal ion recognition |
-
2017
- 2017-12-18 CN CN201711366189.6A patent/CN108303401A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103884701A (en) * | 2014-04-10 | 2014-06-25 | 中国烟草总公司郑州烟草研究院 | Mercury ion detection method |
| CN105352925A (en) * | 2015-10-26 | 2016-02-24 | 中国烟草总公司郑州烟草研究院 | Copper ions detection method based on nano-cluster |
| CN105548131A (en) * | 2016-03-03 | 2016-05-04 | 中国烟草总公司郑州烟草研究院 | Preparation method of array fluorescent nano-cluster sensor and application of array fluorescent nano-cluster sensor to metal ion recognition |
Non-Patent Citations (3)
| Title |
|---|
| ZHIQIN YUAN 等: "Functionalized fluorescent gold nanodots: synthesis and application for Pb2+ sensing", 《CHEMICAL COMMUNICATIONS》 * |
| 张浩琪 等: "荧光金纳米团簇的制备及其在铜离子检测中的应用", 《分析科学学报》 * |
| 李亚娟: "金纳米簇的合成及其应用", 《中国优秀博硕士学位论文全文数据库(硕士) 工程科技Ⅰ辑》 * |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109520984A (en) * | 2018-12-06 | 2019-03-26 | 南通中国科学院海洋研究所海洋科学与技术研究发展中心 | The rapid detection method of sulfate reducing bacteria in a kind of briny environment |
| CN109520984B (en) * | 2018-12-06 | 2021-04-06 | 南通中国科学院海洋研究所海洋科学与技术研究发展中心 | Method for rapidly detecting sulfate reducing bacteria in seawater environment |
| CN111504961A (en) * | 2020-03-31 | 2020-08-07 | 南昌大学 | Fluorescent sensor based on glutathione gold nanoclusters and application thereof |
| CN111504961B (en) * | 2020-03-31 | 2023-05-02 | 南昌大学 | Fluorescent phytic acid detection method based on glutathione gold nanoclusters |
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